CN103260410A - Pesticidal mixtures - Google Patents

Pesticidal mixtures Download PDF

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CN103260410A
CN103260410A CN201180058398.9A CN201180058398A CN103260410A CN 103260410 A CN103260410 A CN 103260410A CN 201180058398 A CN201180058398 A CN 201180058398A CN 103260410 A CN103260410 A CN 103260410A
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mixture
compound
plant
present
propagation material
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M·格韦尔
A·哈泽
E·哈登
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BASF SE
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BASF SE
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/50—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids the nitrogen atom being doubly bound to the carbon skeleton
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines

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  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Synergistic mixtures are provided, which comprise, as active components, one fungicidal compound IA selected from the group consisting of dodemorph, carboxin, propineb, ziram, benodanil, pentachlorphenol, pthalid, or one biological compound IB selected from the Bacillus subtilis var. amyloliquefaciens FZB24, chitosan, Pythium oligandrum DV74, and Reynoutria, sachlinensis; and one fungicidal compound II selected from the group of strobilurines in synergistic effective amounts.

Description

Pesticide combination
The present invention relates to using the Synergistic effective dose and comprise the Synergistic mixture of following component as active component:
1) a kind ofly be selected from following Fungicidal compounds IA: carboxin (carboxin), dodemorfe (dodemorph), spiroxamine (spiroxamin), prodiamine (procymidon), valifenalat, sulphur, 2-(4-chlorphenyl)-N-[4-(3, the 4-Dimethoxyphenyl) different azoles-5-yl]-2-third-2-alkynyloxy group acetamide, 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(1, 2, 3, 4-naphthane-1-yl) acid amides, propineb (propineb), ziram (ziram), tolyfluanid (tolylfluanid), the chloro-1-(4 of 5-, 6-dimethoxypyridin-2-yl)-2-methyl isophthalic acid H-benzimidazole, 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(R)-1, 2, 3, 4-naphthane-1-base acid amides, benodanil (benodanil), pentachlorophenol (pentachlorphenol), Rabcide (phthalid) and guanidine, or
2) a kind of biologic artifact IB that is selected from bacillus subtilis liquefying starch mutation (Bacillus subtilis var.amyloliquefaciens) FZB24, chitosan, pythium oligandrum (Pythium oligandrum) DV74 and giant knotweed (Reynoutria sachlinensis); And
3) a kind ofly be selected from following Fungicidal compounds II: nitrile Fluoxastrobin (azoxystrobin), the fragrant bacterium ester (coumethoxystrobin) of first, SYP-3375 (coumoxystrobin), dimoxystrobin (dimoxystrobin), Enestroburin (enestroburin), fluoxastrobin (fluoxastrobin), imines bacterium (kresoxim-methyl), fork phenalgin acid amides (metominostrobin), orysastrobin (orysastrobin), ZEN 90160 (picoxystrobin), pyraclostrobin (pyraclostrobin), pyrametostrobin, azoles bacterium ester (pyraoxystrobin), pyribencarb, oxime bacterium ester (trifloxystrobin), 2-(o-((2, 5-dimethyl phenoxy methylene) phenyl)-3-methoxy-methyl acrylate, ((3-(2 for 2-for 2-, the 6-dichlorophenyl)-1-methyl acrol amino oxygen ylmethyl) phenyl)-2-methoxyimino-N-methylacetamide.
The mixture of mentioning above these is hereinafter also referred to as " mixture of the present invention ".Compound I A and Compound I B also are referred to as Compound I hereinafter.
In addition, the present invention relates to a kind of method and Compound I and the purposes of Compound I I in such mixture of preparation of using mixture control plant-pathogenic harmful fungoid of the present invention, also relate to the composition that comprises such mixture.
In addition; the present invention relates to a kind of method of preventing and treating the plant-pathogenic harmful fungoid, the method comprises to be made plant-pathogenic harmful fungoid, its habitat, ,Qi place, breeding spot or will protect in case the plant of fungal attack, soil or plant propagation material contact with the mixture as defined above of effective dose.
Extraly, the present invention also comprises a kind of protective plant propagating materials in case the method for plant-pathogenic harmful fungoid, and the method comprises makes plant propagation material contact with the antifungal effective dose with mixture of the present invention.
Term " plant propagation material " is interpreted as meaning that all breedings parts of plant are as seed, and can be for the asexual vegetable material of breeding plant for example, as rice shoot and stem tuber (potato).This comprises seed, root, fruit, stem tuber, bulb, subterranean stem, spray, bud and other plant part, is included in after sprouting or rice shoot and the seedling after emerging, by soil, transplanted.These seedling can also the protection before transplanting by the processing wholly or in part via dipping or pouring.In particularly preferred embodiments, the term propagating materials means seed.
The invention further relates to plant protective mixture of active principles and a kind of method that such mixture of the present invention is applied to plant with the Synergistic raising effect that improves plant health.
Compound I A and II and fungicidal action thereof and their production method are normally known.For example, commercial compound especially can be at The Pesticide Manual, the 14th edition, in British Crop Protection Council (2006), finds.
The chloro-1-of 5-(4,6-dimethoxypyridin-2-yl)-2-methyl isophthalic acid H-benzimidazole and fungicidal action thereof are disclosed in WO2000029404.2-(4-chlorphenyl)-N-[4-(3,4-Dimethoxyphenyl) is different Azoles-5-yl]-2-third-2-alkynyloxy group acetamide and fungicidal action known by WO2004083193.2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(1; 2; 3; 4-naphthane-1-yl) acid amides and 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(R)-1; 2; 3,4-naphthane-1-base acid amides and fungicidal action thereof are disclosed in WO07/14290 and WO08/13622.
Compound I B is commercially available, and bacillus subtilis liquefying starch mutation (Bacillus subtilis var.amyloliquefaciens) FZB24 is for example (Novozyme Biologicals, Inc., USA), chitosan is for example commercial as ARMOUR-ZEN (BotriZen Ltd., New Zealand), and DV74 is for example for pythium oligandrum (Pythium oligandrum)
Figure BDA00003297632600032
(Remeslo SSRO, Biopreparaty, Chez Republic) commercial and giant knotweed (Reynoutria sachlinensis) for example, as Produkt
Figure BDA00003297632600033
(Marrone BioInnovations, USA) is commercial.
The typical problem occurred in the fungi prevention and control field is to need the dose rate that reduces active component to reduce or to avoid hostile environment or toxicity effect, still allows effective fungi control simultaneously.
For the present invention, term plant-pathogenic harmful fungoid is abbreviated as " harmful fungoid " hereinafter.
Another problem run into is need to have the effective available fungi control agent of the harmful fungoid of wide region.
Still need to combine and knock down active and prevent and treat for a long time, be i.e. the fungi control agent of snap action and long-acting.
Another difficulty relevant to the use of fungicide is repetition and uses separately independent Fungicidal compounds and cause in many cases the quick selection of the harmful fungoid of or the tolerance that adapt to natural to described active ingredient deposits yields.Therefore, need to contribute to prevent or overcome the fungi control agent of tolerance.
Another problem that the present invention faces is to improve the composition of plant, usually a kind of and be called hereinafter the method for " plant health ".
The term plant health comprises that each Plants irrelevant with the fungi control improves.For example, the advantageous property that can mention is the crop characteristic of improving, comprise and emerging, crop yield, protein content, oil content, content of starch, the root system (root growth of improvement) of more growing, the stress tolerance of improving is (for example, for arid, heat, salt, UV, water, cold), the ethene (generation of reduction and/or the inhibition of reception) reduced, the increase of tillering, plant height increases, larger blade, dead base leaf still less, stronger tillers, greener leaf look, pigment content, photosynthetic activity, need supply (as fertilizer or water) still less, need seed still less, more voluminous tillers, blooming more early, early stage grain maturity, plant joint (lodging) still less, the spray growth increased, the plant vigor improved, the plant associations that increase and early stage and better sprouting, or any other advantage of knowing of those skilled in the art.
Therefore, the purpose of this invention is to provide and solved the depressant dose rate and/or improved activity profile and/or will knock down that active and long-term control combines and/or the Fungicidal mixture of the problem of tolerance management and/or promotion plant health.
We find that this purpose partially or completely realizes by comprising the compound mixture that starts defined reactive compound.
Especially find that control rate that the defined mixture of beginning and independent compound may reach compares fungi and demonstrates the effect that significantly improves and/or be applicable to improving plant health when being applied to when plant, plant part, plant propagation material (preferred seed) or its are grown place.
Have been found that independent antifungal and/or the plant health improvement effect of reactive compound existed in far super this mixture of effect of mixture of the present invention.
In addition, we find simultaneously, associating or separate administration Compound I with Compound I I or the control rate that administered compound I may reach with individually oriented compound with Compound I I successively compare the control allowed fungi and improve (Synergistic fungicidal mixtures).
In addition, we find simultaneously, associating or separate administration Compound I with Compound I I or the plant health effect that administered compound I may reach with individually oriented compound with Compound I I successively compare the plant health of enhancing effect (Synergistic mixture that wherein the Synergistic phenomenon is plant health Synergistic phenomenon) be provided.
Mixture of the present invention is with the Synergistic effective dose, and the weight ratio of Compound I and component I I of for example take is 500:1-1:500, preferably 100:1-1:100, more preferably 50:1-1:50, even more preferably 20:1-1:20,10:1-1:10 particularly preferably, especially 5:1-1:5 comprises active substance.
In another preferred embodiment, the present invention relates to the mixture of inclusion compound IA and Compound I I.
Preferred mixture inclusion compound IA of the present invention and as nitrile Fluoxastrobin, dimoxystrobin, Enestroburin, fluoxastrobin, imines bacterium, fork phenalgin acid amides, orysastrobin, ZEN 90160, pyraclostrobin, pyribencarb or the oxime bacterium ester of Compound I I.More preferably mixture inclusion compound IA of the present invention and as nitrile Fluoxastrobin, imines bacterium, orysastrobin, ZEN 90160, pyraclostrobin or the oxime bacterium ester of Compound I I.Mixture inclusion compound IA of the present invention and as nitrile Fluoxastrobin, pyraclostrobin or the oxime bacterium ester of Compound I I most preferably.Inclusion compound IA and as the mixture of the pyraclostrobin of Compound I I extremely preferably.
Same preferably mixture inclusion compound IB of the present invention and as nitrile Fluoxastrobin, dimoxystrobin, Enestroburin, fluoxastrobin, imines bacterium, fork phenalgin acid amides, orysastrobin, ZEN 90160, pyraclostrobin, pyribencarb or the oxime bacterium ester of Compound I I.More preferably mixture inclusion compound IB of the present invention and as nitrile Fluoxastrobin, imines bacterium, orysastrobin, ZEN 90160, pyraclostrobin or the oxime bacterium ester of Compound I I.Mixture inclusion compound IB of the present invention and as nitrile Fluoxastrobin, pyraclostrobin or the oxime bacterium ester of Compound I I most preferably.Inclusion compound IB and as the mixture of the pyraclostrobin of Compound I I extremely preferably.
In the mixture of the present invention of inclusion compound IA and Compound I I, preferred Compound I A is selected from carboxin, dodemorfe, spiral shell
Figure BDA00003297632600054
Luxuriant amine, prodiamine, valifenalat, propineb, ziram, tolyfluanid, the chloro-1-(4 of 5-, 6-dimethoxypyridin-2-yl)-2-methyl isophthalic acid H-benzimidazole, 2-(4-chlorphenyl)-N-[4-(3,4-Dimethoxyphenyl) are different
Figure BDA00003297632600052
Azoles-5-yl]-2-third-2-alkynyloxy group acetamide, 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(1; 2; 3; 4-naphthane-1-yl) acid amides and 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(R)-1; 2; 3,4-naphthane-1-base acid amides, preferred Compound I A is selected from carboxin, dodemorfe, spiral shell Luxuriant amine, prodiamine, valifenalat, 2-(4-chlorphenyl)-N-[4-(3,4-Dimethoxyphenyl) are different
Figure BDA00003297632600053
Azoles-5-yl]-2-third-2-alkynyloxy group acetamide and 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-4-thiazolecarboxylic acid methyl-(1; 2; 3; 4-naphthane-1-yl) acid amides, most preferred Compound I A is selected from carboxin, dodemorfe, ziram, benodanil, pentachlorophenol and Rabcide.Extremely preferably comprise as dodemorfe, propineb and the ziram of Compound I A and the mixture of Compound I I.
Also extremely preferred antifungal component is limited to the mixture of sulphur and Compound I I, wherein in these mixtures, Compound I I is preferably selected from nitrile Fluoxastrobin, dimoxystrobin, Enestroburin, fluoxastrobin, imines bacterium, fork phenalgin acid amides, orysastrobin, ZEN 90160, pyraclostrobin, pyribencarb or oxime bacterium ester, be preferably selected from nitrile Fluoxastrobin, imines bacterium, orysastrobin, ZEN 90160, pyraclostrobin or oxime bacterium ester, most preferably be selected from nitrile Fluoxastrobin, pyraclostrobin or oxime bacterium ester, extremely be preferably pyraclostrobin.
Another preferred embodiment of the present invention relates to listed composition in Table A, and wherein a line of Table A is in each case corresponding to comprising a kind of Compound I A of being compiled in corresponding line and the Fungicidal composition of a kind of component I I.Mixture of the present invention is with the Synergistic effective dose, and the weight ratio of Compound I A and component I I of for example take is 500:1-1:500, preferably 100:1-1:100, more preferably 50:1-1:50, even more preferably 20:1-1:20,10:1-1:10 particularly preferably, especially 5:1-1:5 comprises active substance.
In Table A, this paper is used following abbreviation:
I is Compound I 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-thiophene
II is Compound I I azoles-4-formic acid methyl-(1,2,3,4-naphthane-1-yl) acid amides=V1
P=pyraclostrobin 2-(4-the chlorphenyl)-different azoles of N-[4-(3,4-Dimethoxyphenyl)-5-yl]-2-third-2-
T=oxime bacterium ester alkynyloxy group acetamide=V2
A=nitrile Fluoxastrobin propineb=Pne
KM=imines bacterium ziram=Z
PIC=ZEN 90160 tolyfluanid=Toly
The chloro-1-of O=orysastrobin 5-(4,6-dimethoxypyridin-2-yl)-2-methyl isophthalic acid H-benzimidazole=V3
Carboxin=C 2-{1-[2-(5-methyl-3-trifluoromethyl pyrazol-1-yl) acetyl group] piperidin-4-yl }-thiophene
Bacterium=D azoles-4-formic acid methyl-(R)-1,2,3,4-naphthane-1-base acid amides=V4
Spiroxamine=S benodanil=Beno
Prodiamine=Pro pentachlorophenol=Penta
Valifenalat=Vali Rabcide=Pth
Guanidine=Gua
Table A
Figure BDA00003297632600061
Figure BDA00003297632600071
In the mixture of Table A, even more preferably following mixture: A-2, A-8, A-9, A-13, A-14, A-15, A-18, A-24, A-25, A-29, A-30, A-31, A-34, A-40, A-41, A-45, A-46, A-47, more preferably following mixture: A-2, A-8, A-9, A-18, A-24, A-25, A-34, A-40, A-41, most preferably following mixture: A-2, A-8, A-9, A-18, A-24, A-25.Extremely preferred A-2, A-8 and A-9.
Another embodiment of the present invention relates to table B listed composition, and a line of wherein showing B is in each case corresponding to comprising a kind of Compound I B of being compiled in corresponding line and the Fungicidal composition of a kind of component I I.Mixture of the present invention is with the Synergistic effective dose, and the weight ratio of Compound I B and component I I of for example take is 500:1-1:500, preferred 100:1-1:100, and more preferably 10:1-1:100, most preferably 20:1-1:40 (IB:II) comprises active substance.
In table B, this paper is used following abbreviation:
I is Compound I B PIC=ZEN 90160
II is Compound I I O=orysastrobin
P=pyraclostrobin bacillus subtilis liquefying starch mutation (Bacillus subtilis var.
T=oxime bacterium ester amyloliquefaciens) FZB24=B1
A=nitrile Fluoxastrobin chitosan=B2
KM=imines bacterium pythium oligandrum (Pythium oligandrum) DV74=B3
Giant knotweed (Reynoutria sachlinensis)=B4
Table B
Figure BDA00003297632600081
In the mixture of table B, preferred following mixture: B-1, B-2, B-3, B-4, B-5, B-6, B-7, B-8, B-9, B-10, B-11 and B-12, more preferably following mixture: B-1, B-2, B-3 and B-4.
Therefore, the mixture of Table A and table B most preferably, but the more preferably mixture of Table A.
The invention described above mixture (except usining the mixture of sulphur as Compound I A) separately can further comprise one or more insecticides, fungicide, weed killer herbicide.
For purposes of the present invention, mixture of the present invention can change into the normal compound agent, for example solution, emulsion, suspension, pulvis, powder, paste and particle.Type of service depends on and specifically is intended to purpose; Should guarantee in each case the meticulous of mixture of the present invention and be uniformly distributed.Prepared in a known way (referring to US3 by preparaton, 060, 084, EP-A707445 (liquid concentrate), Browning: " Agglomeration ", Chemical Engineering, on December 4th, 1967, 147-48, Perry ' s Chemical Engineer ' s Handbook, the 4th edition, McGraw-Hill, New York, 1963, the 8-57 page reaches each page subsequently, WO91/13546, US4, 172, 714, US4, 144, 050, US3, 920, 442, US5, 180, 587, US5, 232, 701, US5, 208, 030, GB2, 095, 558, US3, 299, 566, Klingman:Weed Control as a Science (J.Wiley& Sons, New York, 1961), Hance etc.: Weed Control Handbook (the 8th edition, Blackwell Scientific, Oxford, 1989) and Mollet, H. and Grubemann, A.:Formulation Technology (Wiley VCH Verlag, Weinheim, 2001).
Agrochemical formulation can also comprise the auxiliary agent in the chemical preparaton that is often used in agriculture.Adjuvant used specific administration form and the active substance of depending on respectively.
The example of suitable auxiliary agents is solvent, solid carrier, dispersant or emulsifier (for example other solubilizers, protective colloid, surfactant and adhesive); organic and inorganic thickening agent, bactericide, antifreezing agent, defoamer, suitable words also have colouring agent and tackifier or adhesive (for example, for the seed treatment preparaton).
Suitable solvent is water, organic solvent, for example, in to high boiling mineral oil fractions as kerosene or diesel oil, also has in addition coal tar, and the oil of plant or animal origin, aliphatic series, ring-type and aromatic hydrocarbons, for example toluene, dimethylbenzene, paraffin, tetrahydronaphthalene, alkylated naphthalene or derivatives thereof, alcohols is as methyl alcohol, ethanol, propyl alcohol, butanols and cyclohexanol, dihydroxylic alcohols, ketone is as cyclohexanone and gamma-butyrolacton, the fatty acid dimethylformamide, fatty acid and fatty acid ester and intensive polar solvent, for example amine is as 1-METHYLPYRROLIDONE.
Solid carrier is that ore deposit soil is as silicate, silica gel, talcum, kaolin, lime stone, lime, chalk, bole, loess, clay, dolomite, diatomite, calcium sulphate, magnesium sulfate, magnesia; The synthetic material ground; Fertilizer is as ammonium sulfate, ammonium phosphate, ammonium nitrate, ureas; And the product of plant origin is as flour, bark powder, wood powder and shuck powder, cellulose powder and other solid carriers.
Suitable surfactant (auxiliary agent, wetting agent, tackifier, dispersant or emulsifier) be aromatic sulfonic acid as lignosulphonic acid (
Figure BDA00003297632600101
type, Norway Borregaard), phenolsulfonic acid, naphthalene sulfonic acids ( type, Akzo Nobel, USA), the dibutyl naphthalene sulfonic acids (
Figure BDA00003297632600103
type, Germany BASF) and the alkali metal salt of fatty acid, alkali salt and ammonium salt, alkylsulfonate, alkylaryl sulfonates, alkyl sulfate, lauryl ether sulfate, aliphatic alcohol sulfate, and sulphation 16-, 17-and the octadecanol compound, the sulphated fatty alcohol glycol ether, also has in addition the condensation product of naphthalene or naphthalene sulfonic acids and phenol and formaldehyde, NONIN HS 240, the ethoxylation isooctylphenol, octyl phenol, nonyl phenol, the alkyl phenyl polyglycol ether, tributyl phenyl polyglycol ether, three stearyl phenyl polyglycol ethers, alkyl aryl polyether alcohol, alcohol and fatty alcohol/ethylene oxide condensation product, ethoxylated castor oil, polyoxyethylene alkyl ether, the ethoxylation polyoxypropylene, laruyl alcohol polyglycol ether acetal, sorbitol ester, the lignin sulfite waste liquor, and protein, albuminate, polysaccharide (for example methylcellulose), hydrophobically modified starch, polyvinyl alcohol (
Figure BDA00003297632600104
type, Switzerland Clariant), polycarboxylate (
Figure BDA00003297632600105
type, German BASF), the poly-alkoxylation thing, polyvinylamine ( type, German BASF), polyvinylpyrrolidone and copolymer thereof.
The example of thickener (giving the mobile performance of preparaton with modification, i.e. high viscosity under quiescent conditions and the low viscous compound in agitation) be polysaccharide and organic and inorganic clay as xanthans (
Figure BDA00003297632600107
CP Kelco, USA),
Figure BDA00003297632600108
23 (French Rhodia),
Figure BDA00003297632600109
(R.T.Vanderbilt, USA) or
Figure BDA000032976326001010
(Engelhard Corp., NJ, USA).
Can add bactericide to preserve and stablize this preparaton.The example of suitable antiseptic agent be based on antiphen (dichlorophene) and benzylalcohol hemiformal those (ICI's
Figure BDA000032976326001011
Or Thor Chemie
Figure BDA000032976326001012
RS and Rohm& Haas's
Figure BDA000032976326001013
MK), and isothiazolinone derivatives as alkyl isothiazole quinoline ketone and BIT class (Thor Chemie
Figure BDA000032976326001014
MBS).
The example of suitable antifreezing agent is ethylene glycol, propane diols, urea and glycerine.
The defoamer example be polysiloxane emulsion (for example
Figure BDA00003297632600111
SRE, German Wacker or France Rhodia), long-chain alcohol, fatty acid, soap, organofluorine compound and composition thereof.
Suitable colouring agent is low aqueous solubility pigment and water-soluble dye.The example that can mention is to have with those of following title: rhodamine B, C.I. pigment red 112, C.I. solvent red 1, pigment blue 15: 4, pigment blue 15: 3, pigment blue 15: 2, pigment blue 15: 1, alizarol saphirol 80, pigment yellow 1, pigment yellow 13, pigment red 112, pigment red 4 8:2, pigment red 4 8:1, paratonere 57:1, paratonere 53:1, pigment orange 43, pigment orange 34, pigment orange 5, pigment green 36, pigment Green 7, Pigment white 6, pigment brown 25, alkaline purple 10, alkalescence purple 49, CI 45430, acid red 52, azogeramine 4, acid blue 9, acid yellow 23, alkali red 1:1 0, alkali red 1:1 08.
The example of tackifier or adhesive be polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and cellulose ether (
Figure BDA00003297632600113
Japan Shin-Etsu).
Powder, broadcasting sowing material and pulvis can be by being present in compound the respective active compounds in mixture of the present invention and suitable other active substances mix with at least one solid carrier or prepared by simultaneous grinding.
Particle can be by preparing active substance and solid carrier adhesion as coated particle, impregnated granules and homogeneous particle.The example of solid carrier is that ore deposit soil is as silica gel, silicate, talcum, kaolin, activated clay (attaclay), lime stone, lime, chalk, bole, loess, clay, dolomite, diatomite, calcium sulphate, magnesium sulfate, magnesia; The synthetic material ground; Fertilizer is as ammonium sulfate, ammonium phosphate, ammonium nitrate, urea; And the product of plant origin is as flour, bark powder, wood powder and shuck powder, cellulose powder and other solid carriers.
The example of preparaton type is suspension (SC, OD, FS), emulsifiable concentrate (EC), emulsion (EW, EO, ES), paste, lozenge, wettable powder or pulvis (WP, SP, SS, WS, DP, DS) can be maybe water-soluble or wettable particle (GR, FG, GG, MG), and for the treatment of plant propagation material the gel formulation (GF) as seed, this paper further exemplifies below in detail:
1. the types of compositions of dilute with water
I) water-soluble concentrate (SL, LS)
The compound of 10 weight portion mixture of the present invention is dissolved in 90 weight parts waters or water-soluble solvent.As an alternative, add wetting agent or other auxiliary agents.Active substance dissolves when dilute with water.Obtain in this way the preparaton that activity substance content is 10 % by weight.
Ii) dispersed concentrate (DC)
Be dissolved in 70 weight portion cyclohexanone by the compound of 20 weight portion mixture of the present invention and add 10 weight portion dispersants as polyvinylpyrrolidone.Dilute with water obtains dispersion.Activity substance content is 20 % by weight.
Iii) emulsifiable concentrate (EC)
Be dissolved in 75 weight portion dimethylbenzene by the compound of 15 weight portion mixture of the present invention and add calcium dodecyl benzene sulfonate and castor oil ethoxylate (5 weight portions in each case).Dilute with water obtains emulsion.The activity substance content of said composition is 15 % by weight.
Iv) emulsion (EW, EO, ES)
Be dissolved in 35 weight portion dimethylbenzene by the compound of 25 weight portion mixture of the present invention and add calcium dodecyl benzene sulfonate and castor oil ethoxylate (5 weight portions in each case).Introduce in 30 weight parts waters by this mixture and make equal phase emulsion by mulser (Ultraturrax).Dilute with water obtains emulsion.The activity substance content of said composition is 25 % by weight.
V) suspension (SC, OD, FS)
The compound of 20 weight portion mixture of the present invention pulverized and added 10 weight portion dispersants and wetting agent and 70 weight parts waters or organic solvent in the ball mill stirred, obtaining active substance suspension in small, broken bits.Dilute with water obtains stable active substance suspension.The activity substance content of said composition is 20 % by weight.
Vi) water-dispersible granule and water-soluble granular (WG, SG)
By the compound grinding in small, broken bits of 50 weight portion mixture of the present invention and add 50 weight portion dispersant and wetting agents, for example, by commercial plant (extruder, spray tower, fluid bed), be made into water dispersible or water-soluble granular.Dilute with water obtains stable active substance dispersion or solution.The activity substance content of said composition is 50 % by weight.
Vii) water dispersible pow-ders and water-soluble powder (WP, SP, SS, WS)
The compound of 75 weight portion mixture of the present invention is ground in the rotor-stator grinding machine and add 25 weight portion dispersants, wetting agent and silica gel.Dilute with water obtains stable active substance dispersion or solution.The activity substance content of said composition is 75 % by weight.
Viii) gel (GF)
The compound of 20 weight portion mixture of the present invention is obtained to the delicate suspensions of active substance in agitating ball mill adding grinding under 10 weight portion dispersants, 1 weight portion gelling agent wetting agent and 70 weight parts waters or organic solvent.Dilute with water obtains the stable suspension of active substance, obtains thus having the composition of 20% (weight) active substance.
2. the types of compositions of using without dilution
Ix) but dusting powder (DP, DS)
By the compound grinding in small, broken bits of 5 weight portion mixture of the present invention and with 95 weight portion kaolin in small, broken bits, fully mix.But this obtains the dusting composition that activity substance content is 5 % by weight.
X) particle (GR, FG, GG, MG)
By the compound grinding in small, broken bits of 0.5 weight portion mixture of the present invention and in conjunction with 99.5 weight portion carriers.Common methods be extrude, atomized drying or bed process.This obtains the particle of using without dilution that activity substance content is 0.5 % by weight.
Xi) ULV solution (UL)
The compound of 10 weight portion mixture of the present invention is dissolved in to 90 weight portion organic solvents as in dimethylbenzene.This obtains the composition of using without dilution that activity substance content is 10 % by weight.
Agrochemical formulation comprises the 0.01-95 % by weight usually, preferably 0.1-90 % by weight, the most preferably active substance of 0.5-90 % by weight.The compound of mixture of the present invention is with 90-100%, and preferably the purity (according to NMR spectrum) of 95-100% is used.
The compound of mixture of the present invention can be directly or with its composition forms (but but for example with Direct spraying solution, powder, suspension, dispersion, emulsion, oil dispersion, paste dusting product, broadcast sowing by material or particle form) by spraying, atomization, dusting, broadcast sowing, brush, flood or water and use.Administration form depends on the purpose be intended to fully; The best that is intended to guarantee in each case the compound that exists in mixture of the present invention may distribute.
Can by emulsion concentrates, paste or wettable powder (sprayable powder, oil dispersion), be prepared by adding water by moisture administration form.For preparation emulsion, paste or oil dispersion, can by wetting agent, tackifier, dispersant or emulsifier by this material directly or after being dissolved in oil or solvent in water homogenizing.Perhaps, can prepare the concentrate and such concentrate that are formed by active substance, wetting agent, tackifier, dispersant or emulsifier and suitable solvent or oil and be suitable for dilute with water.
With the active material concentration in preparation, can in relative broad range, change.They are generally the 0.0001-10 % by weight, preferably the compound of the mixture of the present invention of 0.001-1 % by weight.
The compound of mixture of the present invention also can wherein can be used and comprise the composition that surpasses 95 % by weight active substances successfully for ultra low volume method (ULV), or even uses the active substance that does not contain additive.
Various types of oil, wetting agent, adjuvant, weed killer herbicide, fungicide, other insecticide or bactericide all can add in reactive compound, and suitable words are until just add (bucket mixes) before being close to use.These reagent can be with the compound of mixture of the present invention with 1:100-100:1, and preferably the weight ratio of 1:10-10:1 is mixed.
Composition of the present invention can also contain fertilizer as ammonium nitrate, urea, potash and superphosphate, phytotoxin and plant growth regulator and safener.These can with above-mentioned composition successively or be combined with, suitable words also only add (the mixed thing of bucket) before being close to use.For example can be before or after processing with fertilizer with the present composition plant of spraying.
In mixture, contained compound can be as defined above simultaneously, combine or separate administration, or use successively, wherein select the time interval of each time between using still with q.s, to be present in active position with the active substance of guaranteeing at first to use when using other active substances.Order of administration is usually unimportant to enforcement of the present invention.
According to the present invention; Compound I and Compound I I are interpreted as being illustrated in the active position (harmful fungoid that will prevent and treat or its habitat plant as infected; plant propagation material, especially seed, surface; material or soil and will protect in case the plant of fungal attack; plant propagation material, especially seed, soil; surface, material or space) there are Compound I and Compound I I with effective dose at least simultaneously.
This can pass through with simultaneously, combine (for example, as the mixed thing of bucket) or separate, or administered compound I and Compound I I and realize successively, wherein select the time interval of each time between using still with q.s, to be present in active position with the active substance of guaranteeing at first to use when using other active substances.The order of using is unimportant to enforcement of the present invention.
In mixture of the present invention, the weight ratio of compound depends on the compounds property of mixture of the present invention usually.
The compound of mixture of the present invention can be separately with or partially or completely mutually mixed and prepared the present composition.Can also pack as the multicomponent packaging kit them as binding compositions and further use.
In one embodiment of the invention, packaging kit can comprise that one or more (comprising all) can be for the preparation of the component of agrochemical composition of the present invention.For example, packaging kit can comprise Compound I and Compound I I and/or adjuvant component and/or other agricultural chemical compounds (for example insecticide or weed killer herbicide) and/or growth regulator component.One or more components may be combined or preformulation.Two or more components are provided in those embodiments in packaging kit therein, and independent container may be combined and directly be packaged in to each component as in tank, bottle, bucket, bag, capsule or case.In other embodiments, two or more components of packaging kit can separately be packed, i.e. preformulation not.Packaging kit can directly comprise that one or more containers that separate are as tank, bottle, bucket, bag, capsule or case, the independent component that wherein each container comprises agrochemical composition.In two kinds of forms, a kind of component of packaging kit can separate with other components or together with or as a kind of component of binding compositions of the present invention for the preparation of the present composition.
The user is used for predose device, musette bag sprayer, aerosol can or spraying airplane by the present composition usually.Here this agrochemical composition water and/or buffer are prepared to required application concentration, wherein suitable words can add other auxiliary agents, thereby obtain with spray liquid or agrochemical composition of the present invention.Per hectare agricultural use district uses the 50-500 liter usually, and preferably 100-400 rises and uses spray liquid.
According to an embodiment, the user can own be hybridly prepared into each compound of the mixture of the present invention of composition (or preparaton) in aerosol can, and for example the each several part of the each several part of packaging kit or mixture of the present invention and suitable words can add other auxiliary agents (bucket mixes).
In another embodiment, the user can be hybridly prepared into each compound of mixture of the present invention of composition or partly-premixed component in aerosol can, the for example component of inclusion compound I and Compound I I, and suitable words can add other auxiliary agents and additive (bucket mixes).
In another embodiment, can combine (for example, after bucket mixes) or use successively each component of the present composition or partly-premixed component, for example the component of inclusion compound I and Compound I I.
As mentioned above; the present invention includes a kind of method for harmful fungoid, wherein maybe will protect in case the plant of fungal attack, soil or plant propagation material (preferred seed) with mixture process fungi, its habitat, the ,Qi place, breeding spot of antifungal effective dose.
Advantageously mixture of the present invention is applicable to the following harmful fungoid of control: for example, Albugo (Albugo) (white blister) on ornamental plant, vegetables (white rust (A.candida)) and sunflower (salsify white rust (A.tragopogonis)); For example, for example, for example, Alternaria (Alternaria) (chain lattice spore leaf spot) on vegetables, rape (rape gives birth to chain lattice spores (A.brassicola) or alternaria brassica (A.brassicae)), sugar beet (A.tenuis), fruit, rice, soybean, potato (early epidemic chain lattice spore (A.solani) or chain lattice spore (A.alternata)), tomato (early epidemic chain lattice spore or chain lattice spore) and wheat; Aphanomyces on sugar beet and vegetables (Aphanomyces); Ascochyta on Cereal and vegetables (Ascochyta), for example large wheat husk two spores (A.hordei) on the A.tritici on wheat (anthracnose) and barley; Bipolaris (Bipolaris) and Drechslera (Drechslera) (epigamous: cochliobolus belongs to (Cochliobolus)), the for example helminthosporium maydis on corn (Bipolaris maydis (D.maydis)) or leaf blight (Bipolaris zeicola (B.zeicola)), for example (wheat root-rot Bipolaris (B.sorokiniana) and the rice Bipolaris (B.oryzae) on rice and lawn for example of the spot blight on Cereal; For example, wheat powdery mildew on Cereal (wheat or barley) (Blumeria (old name: Erysiphe) graminis) (powdery mildew); For example, for example, Botrytis cinerea (Botrytis cinerea) (epigamous: Botrytis cinerea (Botryotinia fuckeliana): gray mold) on fruit and berry (strawberry), vegetables (lettuce, carrot, celeriac and cabbage), rape, flowers, grapevine, forest plants and wheat; Lettuce dish stalk mould (Bremia lactucae) (downy mildew) on lettuce; Long beak shell on broad leaf tree and evergreen tree belongs to (Ceratocystis) (synonym line mouth shell belongs to (Ophiostoma)) (rot or droop), for example elm wilt (C.ulmi) (Dutch elm disease) on elm; Corn tail spore bacterium (C.zeae-maydis)), for example, for example, Cercospora (Cercospora) (tail spore leaf spot) on rice, sugar beet (beet is given birth to tail spore (C.beticola)), sugarcane, vegetables, coffee, soybean (Germ To Soybean Frogeye Leaf Spot (C.sojina) or Cercospora kikuchii (C.kikuchii)) and rice corn (gray leaf spot for example:; Leaf mold) and the Cladosporium on Cereal (Cladosporium), for example careless bud branch spore (C.herbarum) (ear rot) on wheat tomato (Cladosporium fulvum (C.fulvum) for example:; Ergot on Cereal (Claviceps purpurea) (ergot); Corn (grey length wriggle spore (C.carbonum)), Cereal (standing grain cochliobolus (C.sativus) for example, phorozoon: wheat root-rot Bipolaris) and rice (palace section cochliobolus (C.miyabeanus) for example, phorozoon: the cochliobolus the long spore (H.oryzae) of wriggling of paddy rice) belongs to (phorozoon: Helminthosporium (Helminthosporium) or Bipolaris) (leaf spot); Droop), for example, for example, perverse dish spore genus (Colletotrichum) (epigamous: enclose small cluster shell Pseudomonas (Glomerella)) (anthracnose) on Kidney bean (bean anthrax bacteria (C.lindemuthianum)) and soybean (Colletotrichum truncatum (C.truncatum) or colletotrichum gloeosporioides Penz (C.gloeosporioides)) cotton (for example cotton anthracnose bacterium (C.gossypii)), corn (for example standing grain is given birth to anthrax bacteria (C.graminicola): anthracnose, stem rot), berry, potato (watermelon anthrax bacteria (C.coccodes) for example:; Corticium (Corticium), for example rice Shang De Bamboo grass wood photovoltaicing leather bacteria (C.sasakii) (banded sclerotial blight); Cucumber Target Leaf Spot bacterium on soybean and ornamental plant (Corynespora cassiicola) (leaf spot); The rust staining germ belongs to (Cycloconium), for example C.oleaginum on Chinese olive tree; Fruit tree, grapevine (C.liriodendri for example, epigamous: Neonectria liriodendri: Blackfoot Disease) and the ginseng on ornamental plant give birth to Ramularia (Cylindrocarpon) (for example fruit tree putrefaction disease or grapevine seedling Blackfoot Disease, epigamous: Nectria (Nectria) or lady's slipper mycorhiza Pseudomonas (Neonectria)); Lineae ablicantes plumage bacterium on soybean (Dematophora (epigamous: Rosellinia) necatrix) (root rot/stem rot); North stem canker Pseudomonas (Diaporthe), for example north of the soybean on soybean stem canker (D.phaseolorum) (vertical withered ulcer); Corn, Cereal for example, as barley (the navel spore (D.teres) of wriggling in the barley filigree, net blotch) and wheat (D.tritici-repentis for example: brown spot), Drechslera (synonym Helminthosporium, epigamous: nuclear cavity Pseudomonas (Pyrenophora)) on rice and lawn; Eschka (Esca) (grapevine droop, die back disease) on the grapevine caused by the brown pore fungi of spot (Formitiporia (synonym Phellinus) punctata), F.mediterranea, Phaeomoniella chlamydospora (old Phaeoacremonium chlamydosporum by name), Phaeoacremonium aleophilum and/or grape seat chamber bacterium (Botryosphaeria obtusa); Anthracnose) and grapevine (grape Elsinochrome (E.ampelina): the Elsinoe anthracnose) (Elsinoe) a kind of fruit, such as apple, pear, etc. (E.pyri), berry (raspberry Elsinochrome (E.veneta):; Rice leaf smut (Entyloma oryzae) (leaf smut) on rice; Epicoccum on wheat (Epicoccum) (smut); Sugar beet (beet powdery mildew (E.betae)), vegetables (for example pea powdery mildew (E.pisi)) for example, for example, as the Erysiphe (Erysiphe) (powdery mildew) on cucurbitaceous plant (two spore powdery mildews (E.cichoracearum)), cabbage, rape (E.cruciferarum); Fruit tree, grapevine and view and admire the side Curvularia lunata (Eutypa lata) (Eutypa canker or droop, phorozoon: Cytosporina lata, synonym Libertella blepharis) on tree; For example, prominent navel Helminthosporium (Exserohilum) (synonym Helminthosporium) on corn (Exserohilum turcicum (E.turcicum)); Fusarium on each Plants (Fusarium) (epigamous: Gibberella (Gibberella)) (droop, root rot or stem rot), for example for example, fusarium graminaria (F.graminearum) on Cereal (wheat or barley) or machete sickle spore (F.culmorum) (root rot, powdery scab or silver point are sick), sharp sickle spore (F.oxysporum) on tomato, the eggplant sickle spore (F.solani) on soybean and the wheel branch sickle spore (F.verticillioides) on corn; For example, gaeumannomyce (Gaeumannomyces graminis) (full rot) on Cereal (wheat or barley) and corn; Cereal (for example Gibberella zeae (G.zeae)) and rice (gibberella fujikuroi (G.fujikuroi) for example: the Gibberella bakanae disease); Cotton anthracnose bacterium (G.gossypii) on apple anthrax bacteria on grapevine, a kind of fruit, such as apple, pear, etc. and other plant (Glomerella cingulata) and cotton; Grainstaining complex on rice; Black rot of grape bacterium on grapevine (Guignardia bidwellii) (black rot); Rust on rosaceous plant and Chinese juniper (Gymnosporangium), for example G.sabinae on pears (rust of pear); Helminthosporium on corn, Cereal and rice (synonym Drechslera, epigamous: cochliobolus belongs to); Camel spore Rust (Hemileia), for example coffee rust on coffee (H.vastatrix) (coffee leaf rust); Foxiness on grapevine is intended Isaria (Isariopsis clavispora) (synonym Cladosporium vitis); Kidney bean shell ball spore on soybean and cotton (Macrophomina phaseolina (synonym phaseoli)) (root rot/stem rot); For example, the withered bacterium of the mould leaf of snow (Microdochium (synonym Fusarium) nivale (snow mold) on Cereal (wheat or barley); Diffusion cross hair shell (Microsphaera diffusa) (powdery mildew) on soybean; Monilia (Monilinia), for example drupe chain sclerotinia sclerotiorum (M.laxa), peach brown rot fungus (M.fructicola) and the M.fructigena on drupe and other rosaceous plants (blossom rot and branch maize ear rot, brown rot); Mycosphaerella on Cereal, banana, berry and peanut (Mycosphaerella), the Fijian ball chamber bacterium (M.fijiensis) (Sigatoka black spot) on the standing grain green-ball chamber bacterium (M.graminicola) on wheat (phorozoon: wheat septoria (Septoria tritici), septoria musiva leaf spot) or banana for example; For example, for example, for example, for example, Peronospora (Peronospora) (downy mildew) on cabbage (rape downy mildew (P.brassicae)), rape (parasitic downy mildew (P.parasitica)), onion (shallot downy mildew (P.destructor)), tobacco (tobacco downy mildew (P.tabacina)) and soybean (downy mildew bacterium (P.manshurica)); Yam bean layer rest fungus (Phakopsora pachyrhizi) and mountain horseleech layer rest fungus (P.Meibomiae) (soybean rust) on soybean; Grapevine (for example P.Tracheiphila and P.tetraspora) and soybean (brown stem rot bacterium (P.gregata) for example: the Phialophora stem rot) (Phialophora) for example; Black shin stem on rape and cabbage is selected the beet stem point mould (P.betae) (root rot, leaf spot and damping-off) on mould (Phoma lingam) (root rot and stem rot) and sugar beet; Sunflower, grapevine (for example black rot of grape bacterium (P.viticola): dead arm and leaf spot) and soybean (stem rot: P.phaseoli for example, epigamous: the Phomopsis (Phomopsis) soybean north stem canker (Diaporthe phaseolorum)); Maize brown spot bacterium on corn (Physoderma maydis) (brown spot); Each Plants for example, for example, as green pepper and cucurbitaceous plant (Phytophthora capsici (P.capsici)), soybean (soybean phytophthora (P.megasperma), late blight) and for example, Phytophthora (Phytophthora) (droop on broad leaf tree (robur sudden death pathogen (P.ramorum): Oak Tree is anxious dead sick) synonym P.sojae), potato and tomato (phytophthora infestans (P.infestans) for example:, root rot, leaf rot, stem rot and fruit tree putrefaction disease); Plasmodiophora brassica bacteria on cabbage, rape, radish and other plant (Plasmodiophora brassicae) (clubroot); Peronospora (Plasmopara), for example the grape on grapevine is given birth to the Plasmopara Halstedll (P.halstedii) on single shaft mould (P.viticola) (grapevine downy mildew) and sunflower; Podosphaera on rosaceous plant, hops, a kind of fruit, such as apple, pear, etc. and berry (Podosphaera) (powdery mildew), for example the apple mildew bacterium (P.leucotricha) on apple; The virus disease that Cereal belongs to (Polymyxa) and propagates thus as the many Acarasiales on barley and wheat (Polymyxa Graminis (P.graminis)) and sugar beet (Polymyxa betae (P.betae)); Cereal is as wheat-based maize ear rot bacterium (Pseudocercosporella herpotrichoides) (eye spot, epigamous: Tapesia yallundae) on wheat or barley; Pseudoperonospora on each Plants (Pseudoperonospora) (downy mildew), for example the humulus false frost of grass (P.humili) on the false downy mildew (P.cubensis) of the Cuba on Curcurbitaceae or hops; Pseudopezicula tracheiphila on grapevine (the burnt germ of grape angle variegated leaf or ' rotbrenner ', phorozoon: Saksenaea (Phialophora)); Puccinia on each Plants (Puccinia) (rust), for example Cereal is as wheat, wheat handle rest fungus (P.triticina) (leaf rust or leaf rust) on barley or rye, bar shaped handle rust (P.striiformis) (stripe rust or yellow rust), barley handle rust (P.hordei) (barley yellow dwarf leaf rust), puccinia graminis (P.graminis) (stem rust or stalk rust) or puccinia triticinia (P.recondita) (leaf rust or leaf rust), Asparagus handle rust (P.asparagi) on Puccinia kuehnii on sugarcane (P.Kuehnii) (orange rust) and asparagus, wheat yellow blothch bacterium on wheat (Pyrenophora (phorozoon: Drechslera) tritici-repentis) the navel spore (P.teres) (net blotch) of wriggling in the barley filigree on (brown spot) or barley, Pyricularia Sacc. (Pyricularia), for example piricularia oryzae (P.grisea) on the Pyricularia oryzae on rice (P.oryzae) (epigamous: Magnaporthe grisea, rice blast) and lawn and Cereal, for example, pythium (Pythium) (damping-off) on lawn, rice, corn, wheat, cotton, rape, sunflower, soybean, sugar beet, vegetables and various other plant (Pythium ultimum bacterium (P.ultimum) or melon and fruit corruption mould (P.aphanidermatum)), Ramularia (Ramularia), for example the beet leaf spot fungi (R.Beticola) on the R.collo-cygni on barley (post every the spore leaf spot, physiology leaf spot) and sugar beet, Rhizoctonia (Rhizoctonia) on cotton, rice, potato, lawn, corn, rape, potato, sugar beet, vegetables and various other plant, the Rhizoctonia solani Kuhn on soybean (R.solani) (root rot/stem rot) for example, the Rhizoctonia cerealis (R.cerealis) (wheat sharp eyespot) on the R.solani on rice (banded sclerotial blight) or wheat or barley, Rhizopus stolonifer on strawberry, carrot, cabbage, grapevine and tomato (Rhizopus stolonifer) (black points, soft rot), rye beak spore (Rhynchosporium secalis) (powdery scab) on barley, rye and triticale, rice broom branch on rice mould (Sarocladium oryzae) and S.attenuatum (sheath rot disease), vegetables and field crop for example, for example, as the Sclerotinia (Sclerotinia) (stem rot or southern blight) on rape, sunflower (sclerotinite (Sclerotinia sclerotiorum)) and soybean (S.rolfsii or rape sclerotinite (S.sclerotiorum)), Septoria on each Plants (Septoria), the soybean septoria musiva (S.glycines) (brown spot) on soybean for example, the many spores of the withered shell of grain husk on the wheat septoria on wheat (S.tritici) (septoria musiva leaf spot) and Cereal (S. (synonym Stagonospora) nodorum) (spot blight), grape snag shell on grapevine (Uncinula (synonym Erysiphe) necator) (powdery mildew, phorozoon: Oidium tuckeri), for example, leaf blight Pseudomonas (Setosphaeria) (leaf spot) on corn (Exserohilum turcicum (S.turcicum), the large spot Exserohilum of synonym (Helminthosporium turcicum)) and lawn, head smut), the axle Ustilago (Sphacelotheca) (smut) on Chinese sorghum and sugarcane corn (silk axle smut (S.reiliana) for example:, monofilament shell powdery mildew (Sphaerotheca fuliginea) (powdery mildew) on cucurbitaceous plant, powder scab bacterium (Spongospora subterranea) (powdery scab) on potato and the virus disease of propagating thus, Stagonospora on Cereal (Stagonospora), for example (spot blight has condition to the many spores of the withered shell of the grain husk on wheat (S.nodorum): clever withered ball chamber bacterium (Leptosphaeria[synonym Phaeosphaeria] nodorum)), synchytrium endobioticum percival on potato (Synchytrium endobioticum) (potato canker), Exoascus (Taphrina), for example lopsided external capsule bacterium (T.Deformans) (leaf-curl) on peach and Lee's external capsule bacterium (T.pruni) (cystocarp Lee) on Lee, Thiclaviopsis on tobacco, a kind of fruit, such as apple, pear, etc., vegetables, soybean and cotton (Thielaviopsis) (black root rot), for example black root rot bacterium (T.basicola) (synonym Chalara elegans), Tilletia on Cereal (Tilletia) (bunt or the bunt smut of wheat), for example T.tritici on wheat (synonym T.caries, the bunt of wheat) and T.controversa (dwarf bunt), meat spore core coral bacterium (Typhula incarnata) (grey snow mold) on barley or wheat, Ustilago (Urocystis), for example hidden the smut (U.occulta) (bar smut) on rye, vegetables for example, for example, belong to (Uromyces) (rust) as the rust of the monospore on Kidney bean (wart top uromyce (U.appendiculatus), synonym U.phaseoli) and sugar beet (rust of beet (U.betae)), Cereal (for example wheat loose smut (U.nuda) and U.avaenae), smut of maize) and the Ustilago on sugarcane (Ustilago) (smut) corn (Ustilago maydis (U.maydis) for example:, for example, Venturia (Venturia) (scab) on apple (scab of apple (V.inaequalis)) and pears, and the Verticillium (Verticillium) (droop) on each Plants if tree and ornamental plant, grapevine, berry, vegetables and field crop, for example the eggplant verticillium wilt pathogen (V.dahliae) on strawberry, rape, potato and tomato.
Mixture of the present invention for example also is applicable to preventing and treating, in material (timber, paper, paint dispersion, fiber or fabric) protection and the fungal disease occurred in the protection of stored prod.Term " material protection " be interpreted as meaning safeguard industries and non-living body material as adhesive, glue, timber, paper and cardboard, textile, leather, paint dispersion, plastics, cooling lubricant, fiber or fabric in case harmful microorganism infecting and destroying as fungus and bacterium.Protection for timber and other materials, should note following harmful fungoid especially: Ascomycetes (Ascomycetes) fungi, for example line mouth shell belongs to, long beak shell belongs to, Aureobasidium pullulans (Aureobasidium pullulans), and Sclerophoma belongs to, Chaetomium (Chaetomium spp.), Humicola (Humicola spp.), Peter's shell belongs to (Petriella spp.), the mould genus of pieces (Trichurus spp.), Basidiomycetes (Basidiomycetes) fungi, for example cellar fungus belongs to (Coniophora spp.), Coriolus Qu61 (Coriolus spp.), sticky gill fungus belongs to (Gloeophyllum spp.), Lentinus (Lentinus spp.), Pleurotus (Pleurotus spp.), sleeping hole belongs to (Poria spp.), Merulius (Serpula spp.) and Tyromyces (Tyromyces spp.), deuteromycetes (Deutero-mycetes) fungi, aspergillus (Aspergillus spp.) for example, Cladosporium, Penicillium (Penicillium spp.), trichoderma (Trichorma spp.), Alternaria, paecilomyces (Paecilomyces spp.) and Zygomycetes (Zygomycetes) fungi, mucor (Mucor spp.) for example, should note following yeast fungus in this external stored prod protection: candida (Candida spp.) and saccharomyces cerevisiae (Saccharomyces cerevisae).
" antifungal effective dose " typically refers to the amount of the composition that growth is obtained the required mixture of the present invention of observable effect or comprises this mixture, described effect comprises necrosis, death, retardance, prevention and removal effect, execution or the appearance of minimizing target organism and movable effect.For the various mixtures/combinations of using in the present invention, the antifungal effective dose can change.The antifungal effective dose of mixtures/combinations also can change as required fungicidal effect and duration, weather, target species, place, mode of administration etc. according to essential condition.
Mixture of the present invention for various cultivated plants as Cereal, for example wheat, rye, barley, triticale, oat or rice; Beet, for example sugar beet or fodder beet; Fruit is as a kind of fruit, such as apple, pear, etc., drupe or berry, for example apple, pears, Lee, peach, almond, cherry, strawberry, raspberry, blackberry, blueberry or dayberry; Leguminous plant, for example French beans, pea, clover or soybean; Oil plants, for example rape, leaf mustard, olive, sunflower, coconut, cocoa bean, castor oil plant, oil palm, peanut or soybean; Cucurbitaceous plant, for example pumpkin, cucumber or muskmelon; Fibre plant, for example cotton, flax, hemp or jute; Cedra fruits, for example orange, lemon, grapefruit or tangerine; Vegetables, for example spinach, lettuce, asparagus, cabbage, carrot, onion, tomato, potato, cucurbit or green pepper; Bay class plant, for example avocado, Chinese cassia tree or camphor; Energy and material plant, for example corn, soybean, rape, sugarcane or oil palm; Corn; Tobacco; Nut; Coffee; Tea; Banana; Grape vine (table grapes and wine brewing grape); Lupulus; Lawn; Stevia (also claiming stevia rebaudianum (Stevia)); Natural rubber plant or view and admire and forest plants, for example flowers, shrub, broad-leaved tree or evergreen tree, for example coniferous tree; And plant propagation material is as a large amount of harmful fungoids of control or insect particular importance in the crop material of seed and these plants.
Preferably mixture of the present invention is used for to control in field crop, for example potato, sugar beet, tobacco, wheat, rye, barley, oat, rice, corn, cotton, soybean, rape, leguminous plant, sunflower, coffee or sugarcane; Fruit; Grape vine; Ornamental plants or vegetables are as a large amount of fungies on cucumber, tomato, Kidney bean or pumpkin.More preferably mixture of the present invention is used for to control fruits and vegetables, as a large amount of fungies on cucumber, tomato, Kidney bean or pumpkin.
Preferably by mixture of the present invention, the processing to plant propagation material is used at Cereal, as wheat, rye, barley and oat, and a large amount of fungies of control on rice, corn, cotton and soybean.
As mentioned above, the present invention includes a kind of method of improving plant health, wherein with the place of the mixture process plant of the present invention of plant health effective dose, wherein plant growth or expection growth or grow the plant propagation material of plant by it.
Term " plant health effective dose " means to be enough to realize the hereinafter mixture amount of the present invention of defined plant health effect.More exemplary information of amount, method of application and proper ratio about using have below been provided.Yet those of skill in the art fully know this amount may change and depend on various factors in wide region, as processed cultivated plant or material and this fact of weather conditions.
Term " effective dose " comprises term " plant health effective dose " and/or " antifungal effective dose " surely with situation.
" place " refers to conk or possibility growing plants, plant propagation material (preferred seed), soil, zone, material or environment.
When preparing mixture, preferably use pure reactive compound, can add wherein as required other reactive compounds that resist insect, as Insecticides (tech) & Herbicides (tech), fungicide or weeding or growth regulating-activity compound or fertilizer as other active components.
Mixture of the present invention is processed fungi by the reactive compound by the antifungal effective dose and maybe will be protected in case the plant of fungal attack, plant propagation material (preferred seed), material or soil are used.Using can be at material, plant or plant propagation material (preferred seed) by before fungal infection and carry out afterwards.
Mixture of the present invention is preferably processed fungi by the reactive compound by the antifungal effective dose via foliage applying and maybe will be protected in case the plant of fungal attack or soil are used.Now use also and can carry out before plant is by fungal infection and afterwards.
In the method for control harmful fungoid, depend on type of compounds and required effect, the rate of application of mixture of the present invention is 0.1-10000g/ha, preferably 2-2500g/ha, more preferably 5-1000g/ha, most preferably 10-750g/ha, especially 20-500g/ha.
For the present invention, the term plant refers to the propagating materials of whole plant, plant part or plant.
Can comprise all genetically modified plants or genetically modified plants with the plant of mixture process of the present invention and the propagating materials of described plant, the crop of the effect of herbicide-tolerant or fungicide or insecticide due to breeding (comprising gene engineering method) for example, or compare the plant of the characteristic with modified with existing plant, they for example can and/or produce mutant or produce by the restructuring program by traditional breeding way.
For example, mixture of the present invention also can (as in seed treatment, spraying processing, ditch dug with a plow or by any other measure) be applied to the plant of having modified by breeding, mutagenesis or gene engineering, includes but not limited to the agricultural biotechnologies product (referring to http://www.bio.org/speeches/pubs/er/agri_products.asp) of list marketing or exploitation.Genetically modified plant is that its genetic material is difficult for the plant of modifying by the recombinant DNA technology of hybridizing, suddenling change or restructuring obtaining naturally under field conditions (factors) by using.Usually by one or more gene integrations in the genetic material of genetically modified plant to improve some performance of plant.This genoid is modified the target posttranslational modification that also includes but not limited to protein, oligopeptides or polypeptide, for example by glycosylation or polymer addition as isoprenylation, acetylization or farnesylation structure division or PEG structure division.
The plant of having modified by breeding, sudden change or gene engineering for example tolerates the herbicide application of special category because of conventional breeding or gene engineering method, these weed killer herbicides as the auximone weed killer herbicide as dicamba (dicamba) or 2,4-D; The bleaching agent weed killer herbicide is as medical midbodies of para (ortho)-hydroxybenzoic acetone acid dioxygenase enzyme (HPPD) inhibitor or phytoene desaturase (PDS) inhibitor; Acetolactate synthestase (ALS) inhibitor, for example sulfonylurea or imidazolone type; Enol pyruvylshikimate 3-phosphate synthase (EPSPS) inhibitor, for example glyphosate (glyphosate); Glutamine synthelase (GS) inhibitor, for example careless ammonium phosphine (glufosinate); Protoporphyrinogen-IX oxidase inhibitor; The lipoid biosynthesis inhibitor is as acetyl group CoA carboxylase (ACCase) inhibitor; Or oxynil (being Brominal (bromoxynil) or ioxynil (ioxynil)) weed killer herbicide.In addition, by genetic modification repeatedly, make Plant Tolerance plurality of classes weed killer herbicide, as tolerance glyphosate and careless ammonium phosphine the two or tolerance glyphosate and be selected from another classification as the weed killer herbicide of ALS inhibitor, HPPD inhibitor, auximone weed killer herbicide or ACCase inhibitor the two.These herbicide tolerant technology for example are described in Pest Managem.Sci.61,2005,246; 61,2005,258; 61,2005,277; 61,2005,269; 61,2005,286; 64,2008,326; 64,2008,332; Weed Sci.57,2009,108; Austral.J.Agricult.Res.58,2007,708; Science316,2007,1185; And in the document of wherein quoting.Several cultivated plants, by conventional breeding (mutagenesis) method herbicide-tolerant, for example tolerate imidazolone type as imazamox (imazamox)
Figure BDA00003297632600241
Summer sowing rape (Canola, German BASF SE) or tolerance sulfonylurea, for example tribenuron-methyl (tribenuron) Sunflower (DuPont, USA).With gene engineering method give cultivated plant as soybean, cotton, corn, beet and rape to weed killer herbicide the tolerance as glyphosate and careless ammonium phosphine, some in them can be with trade name
Figure BDA00003297632600243
(tolerance glyphosate, Monsanto, U.S.A.), (tolerance imidazolone, German BASF SE) and
Figure BDA00003297632600245
(tolerating careless ammonium phosphine, German Bayer CropScience) obtains.
In addition, also comprise by using recombinant DNA technology and can synthesize one or more insecticidal proteins, especially by bacillus (Bacillus) bacterial isolates, the plant of known those of bacillus thuringiensis (Bacillus thuringiensis) particularly, described insecticidal proteins is as delta-endotoxin, CryIA (b) for example, CryIA (c), CryIF, CryIF (a2), CryIIA (b), CryIIIA, CryIIIB (b1) or Cry9c; Asexual insecticidal proteins (VIP), for example VIP1, VIP2, VIP3 or VIP3A; Nematode is settled down the insecticidal proteins of bacterium, for example Photobacterium (Photorhabdus) or Xenorhabdus (Xenorhabdus); The toxin that animal produces is as scorpion toxin, spider toxin, wasp toxin or other insect-specific neurotoxins; Mycetogenetic toxin, for example streptomyces (Streptomycetes) toxin; Phytolectin, for example pea or barley lectin element; Agglutinin; Protease inhibitors, trypsin inhibitor for example, serpin, patatin, cystatin or antipain; Ribosome inactivating protein (RIP), for example ricin, corn-RIP, abrin, Seeds of Luffa cylindrica albumen, saporin or different strain diarrhoea toxalbumin (bryodin); Steroid metabolism enzyme, for example 3-hydroxy steroid oxidase, ecdysteroids-IDP glycosyl transferase, cholesterol oxidase, moulting hormone inhibitor or HMG-CoA reductase; Ion channel blocking agent, for example sodium channel or calcium channel blocker; Juvenile hormone esterase; Diuretic hormone acceptor (helicokinin acceptor);
Figure BDA00003297632600258
Synzyme, bibenzyl synzyme, chitinase or dextranase.For the present invention, these insecticidal proteins or toxin also should specifically be interpreted as front toxin, hybrid protein, albumen brachymemma or other aspect modifications.Hybrid protein is characterised in that the novel combination (for example, referring to WO02/015701) in albumen territory.Other examples that this toxoid maybe can synthesize the genetically modified plant of these toxin for example are disclosed in EP-A374753, WO93/007278, WO95/34656, EP-A427529, EP-A451878, WO03/18810 and WO03/52073.Produce the method for these genetically modified plants normally known to those skilled in the art and for example be described in above-mentioned publication.These are contained in insecticidal proteins in genetically modified plant and give the plant that produces these albumen and take to being the tolerance of arthropodan insect, especially beetle (coleoptera (Coleoptera)), dipteran (diptera (Diptera)) and moth (Lepidoptera (Lepidoptera)) and nematode (Nematoda (Nematoda)) on all taxonomy.The genetically modified plant that can synthesize one or more insecticidal proteins for example is described in above-mentioned publication, and some in them are commercially available, for example
Figure BDA00003297632600251
(producing the corn variety of toxin C ry1Ab), Plus (producing the corn variety of toxin C ry1Ab and Cry3Bb1), (producing the corn variety of toxin C ry9c),
Figure BDA00003297632600254
RW (producing the corn variety of toxin C ry34Ab1, Cry35Ab1 and enzyme phosphinothricin-N-acetyl-transferase [PAT]),
Figure BDA00003297632600255
33B (producing the cotton variety of toxin C ry1Ac),
Figure BDA00003297632600256
I (producing the cotton variety of toxin C ry1Ac), II (producing the cotton variety of toxin C ry1Ac and Cry2Ab2),
Figure BDA00003297632600261
(producing the cotton variety of VIP toxin),
Figure BDA000032976326002610
(producing the potato kind of toxin C ry3A),
Figure BDA00003297632600262
Figure BDA00003297632600263
Figure BDA00003297632600264
Figure BDA00003297632600266
Bt11 (for example
Figure BDA00003297632600267
CB) and the Bt176 of French Syngenta Seeds SAS (producing the corn variety of toxin C ry1Ab and PAT enzyme), the MIR604 of France Syngenta Seeds SAS (produces the corn variety of the modification translation of toxin C ry3A, referring to WO03/018810), the MON863 (producing the corn variety of toxin C ry3Bb1) of Belgium Monsanto Europe S.A., the IPC531 (producing the cotton variety of the modification translation of toxin C ry1Ac) of Belgium Monsanto Europe S.A. and 1507 (the producing the corn variety of toxin C ry1F and PAT enzyme) of Belgian Pioneer Overseas Corporation.
In addition, also comprise by using recombinant DNA technology and can synthesize one or more albumen to increase its plant to resistance or the tolerance of bacterium, virus or fungal pathogens.The example of this plastein is so-called " albumen relevant to pathogenesis " (PR albumen, for example see EP-A392225), Plant Genes Conferring Resistance To Pathogens (for example expressing the potato cultivar for the resistant gene of the phytophthora infestans (Phytophthora infestans) from wild Mexico potato Solanum bulbocastanum) or T4 Lysozyme (for example can synthesize and bacterium be strengthened to the potato cultivar of these albumen of resistance as Erwinia amylvora has).It is known and for example be described in above-mentioned publication that the method for producing this genoid modified plant is generally those skilled in the art.
In addition, for example also comprise, by using recombinant DNA technology can synthesize the output (yield of biomass, Grain Yield, content of starch, oil content or protein content) of one or more protein to improve these plants, to the tolerance of arid, salt or other growth restriction environmental factors or to the plant of the tolerance of insect and fungi, bacterium or its viral pathogen.
In addition, also comprise especially and contain the content of material of the amount of changing or the plant of novel substance content in order to improve the mankind or Animal nutrition by the use recombinant DNA technology, (for example for example produce the oil crop of sanatory long-chain omega-fatty acid or unsaturated ω-9 fatty acid
Figure BDA00003297632600268
Rape, Canadian DOW Agro Sciences).
In addition, also comprise especially and contain the content of material of the amount of changing or the plant of novel substance content in order to improve raw material production by the use recombinant DNA technology, (for example for example produce the potato of the amylopectin content increased
Figure BDA00003297632600269
Potato, German BASF SE).
In other embodiments of the present invention, root and spray by mixture of the present invention for the protection of seed and rice shoot, preferred seed.
Seed treatment can be carried out planting before large Tanaka in seed-box.
In order to process seed, the weight ratio in mixture of the present invention depends on the compounds property of mixture of the present invention usually.
Especially can be for example for the composition of seed treatment:
The A solubility concentrates thing (SL, LS)
D emulsion (EW, EO, ES)
E suspension (SC, OD, FS)
F water-dispersible granule and water-soluble granular (WG, SG)
G water dispersible pow-ders and water-soluble powder (WP, SP, WS)
H gel formulation (GF)
But I dusting powder (DP, DS)
These compositions can or be applied to without dilution on plant propagation material, particularly seed through dilution.These compositions can or be applied to without dilution on plant propagation material, particularly seed through dilution.Described composition is doubly rear in sight with obtaining the 0.01-60 % by weight in preparation at dilution 2-10, preferably the active material concentration of 0.1-40 % by weight.Use can the sowing before or during carry out.Respectively agrochemistry mixture and composition thereof are applied to plant propagation material, especially on seed or be known by the method for its processing in this area and comprise seed dressing, dressing, granulation, dusting and the immersion application process (and also having processing in ditch dug with a plow) of propagating materials.In preferred embodiments, by not bringing out the method for sprouting, for example seed dressing, granulation, dressing and dusting are applied to compound or its composition on plant propagation material respectively respectively.
In the processing of plant propagation material (preferred seed), the rate of application of mixture of the present invention is usually for formulated product (usually comprising the 10-750g/l active matter).
The invention still further relates to the breeding product of plant, especially seed, it comprises, and scribbles and/or the composition of the mixture that contains mixture as defined above or comprise two or more active components or two or more provide the mixture of the composition of one of active component separately.Plant propagation material (preferred seed) is with 0.1g-10kg/100kg plant propagation material (preferred seed), and preferably the amount of 0.1g-1kg/100kg plant propagation material (preferred seed) comprises mixture of the present invention.
For example, the weight ratio of Compound I I is preferably 0.5-200g/100kg plant propagation material (preferred seed) at this paper, more preferably 1-50g/100kg plant propagation material (preferred seed), most preferably 1-20g/100kg plant propagation material (preferred seed).
For example, the weight ratio of Compound I is preferably 1-2000g/100kg plant propagation material (preferred seed) at this paper, more preferably 10-1000g/100kg plant propagation material (preferred seed), 25-750g/100kg plant propagation material (preferred seed) most preferably, extremely preferably 50-500g/100kg plant propagation material (preferred seed).
Separately or the compound of co-administered mixture of the present invention by before or after plant seeding or before or after plant emerges, seed, rice shoot, plant or soil spraying or dusting being carried out.
The present invention is further illustrated by the following example, but not limited by the following example.
In methyl-sulfoxide, reactive compound is mixed with separately to the stock solution that concentration is 10000ppm.
Embodiment 1-to the activity of late blight pathogene phytophthora infestans (Phytin)
Stock solution is mixed according to ratio, move on to titer plate (MTP) and go up and be diluted with water to described concentration.Then the spore suspension that adds the phytophthora infestans that contains the moisture nutrient medium of pea juice base or DDC medium.Each plate is put at the temperature of 18 ° of C to the steam-laden chamber.Inoculating used absorption spectrophotometry to measure MTP under 405nm after 7 days.
The results are shown in following table 1.By the parameter measured with containing the growth (=100%) of the scheme that contrasts of reactive compound and the blank value that do not contain fungi and reactive compound, do not compare, to determine the relative growth percentage of pathogene in each reactive compound.The expection effect of active compound combinations is used Colby formula [R.S.Colby, " calculate Synergistic and the antagonism response of combinations of herbicides ", Weeds15,20-22 (1967)] determine and compare to show the synergistic function of mixture of the present invention with the effect of observing.
Table 1
Figure BDA00003297632600281
*) according to Colby
Embodiment 2-to the activity of the leaf spot that caused by wheat septoria (Septtr) on wheat
Stock solution is mixed according to ratio, move on to titer plate (MTP) and go up and be diluted with water to described concentration.Then add the spore suspension of wheat septoria in biological malt water solution or yeast-bacto peptone-glycerite.Each plate is put at the temperature of 18 ° of C to the steam-laden chamber.Inoculating used absorption spectrophotometry to measure MTP under 405nm after 7 days.
The results are shown in following table 2.By the parameter measured with containing the growth (=100%) of the scheme that contrasts of reactive compound and the blank value that do not contain fungi and reactive compound, do not compare, to determine the relative growth percentage of pathogene in each reactive compound.The expection effect of active compound combinations is used Colby formula [R.S.Colby, " calculate Synergistic and the antagonism response of combinations of herbicides ", Weeds15,20-22 (1967)] determine and compare to show the synergistic function of mixture of the present invention with the effect of observing.
Table 2
Figure BDA00003297632600291
*) according to Colby
Embodiment 3-to the activity of the stem rot that caused by Rhizoctonia solani Kuhn (Rhizso)
Stock solution is mixed according to ratio, move on to titer plate (MTP) and go up and be diluted with water to described concentration.Then add the spore suspension of Rhizoctonia solani Kuhn in biological malt water solution or yeast-bacto peptone-glycerite.Each plate is put at the temperature of 18 ° of C to the steam-laden chamber.Inoculating used absorption spectrophotometry to measure MTP under 405nm after 7 days.
The results are shown in following table 3.By the parameter measured with containing the growth (=100%) of the scheme that contrasts of reactive compound and the blank value that do not contain fungi and reactive compound, do not compare, to determine the relative growth percentage of pathogene in each reactive compound.The expection effect of active compound combinations is used Colby formula [R.S.Colby, " calculate Synergistic and the antagonism response of combinations of herbicides ", Weeds15,20-22 (1967)] determine and compare to show the synergistic function of mixture of the present invention with the effect of observing.
Table 3
Figure BDA00003297632600301
*) according to Colby

Claims (15)

1. the Synergistic effective dose of usining comprises the mixture of following component as active component:
1) a kind of Fungicidal compounds IA that is selected from dodemorfe (dodemorph), carboxin (carboxin), propineb (propineb), ziram (ziram), benodanil (benodanil), pentachlorophenol (pentachlorphenol) and Rabcide (pthalid); Or
2) a kind of biologic artifact IB that is selected from bacillus subtilis liquefying starch mutation (Bacillus subtilis var.amyloliquefaciens) FZB24, chitosan, pythium oligandrum (Pythium oligandrum) DV74 and giant knotweed (Reynoutria sachlinensis); With
3) a kind of Fungicidal compounds II that is selected from the strobilurins class.
2. according to the mixture of claim 1, its inclusion compound IA and Compound I I, wherein Compound I I is selected from dodemorfe, carboxin, propineb, ziram, benodanil, pentachlorophenol and Rabcide.
3. according to the mixture of claim 1 or 2, wherein Compound I A is dodemorfe.
4. according to the mixture of claim 1 or 2, wherein Compound I A is propineb.
5. according to the mixture of claim 1 or 2, wherein Compound I A is ziram.
6. according to the mixture of claim 1, its inclusion compound IB and Compound I I.
7. according to the mixture of any one in claim 1-6, wherein Fungicidal compounds II is selected from nitrile Fluoxastrobin (azoxystrobin), pyraclostrobin (pyraclostrobin) and oxime bacterium ester (trifloxystrobin).
8. according to the mixture of any one in claim 1-6, wherein Fungicidal compounds II is pyraclostrobin.
9. according to the mixture of any one in claim 1-8, wherein wt is than being 1:500-500:1.
10. a Fungicidal composition, comprise liquid or solid carrier and mixture as defined as any one in claim 1-9.
11. a method of preventing and treating fungi, wherein with mixture process fungi as defined as any one in claim 1-9, its habitat of effective dose, ,Qi place, breeding spot maybe will protect in case the plant of fungal attack, soil or plant propagation material.
12. a method of improving plant health, wherein with the place of the mixture process plant as defined as any one in claim 1-9 of effective dose, wherein plant growth or expection growth or grow the plant propagation material of plant.
13. a protective plant propagating materials in case the method for fungi comprise plant propagation material contacted with the antifungal effective dose with mixture as defined as any one in claim 1-5.
14. method as desired as any one in claim 11-13, wherein simultaneously, combine or separate, or using successively compound as defined as any one in claim 1-9.
15. plant propagation material, comprise mixture as defined as any one in claim 1-9 with the amount of 0.01g-10kg/100kg plant propagation material.
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UA125210C2 (en) 2016-03-16 2022-02-02 Басф Се Use of tetrazolinones for combating resistant phytopathogenic fungi on cereals
EP3429358A1 (en) 2016-03-16 2019-01-23 Basf Se Use of tetrazolinones for combating resistant phytopathogenic fungi on fruits
WO2017157916A1 (en) 2016-03-16 2017-09-21 Basf Se Use of tetrazolinones for combating resistant phytopathogenic fungi on soybean
US11331356B2 (en) 2016-07-01 2022-05-17 Bio Agens Research And Development—Bard, S.R.O. Preparation with the mycoparasitic microorganism pythium oligandrum for the treatment of dermaphytoses and yeast infections on the skin and mucouses, method of determing the cell's viability of the microorganism pythium oligandrum and method of applying the preparation

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3060084A (en) 1961-06-09 1962-10-23 Du Pont Improved homogeneous, readily dispersed, pesticidal concentrate
US3299566A (en) 1964-06-01 1967-01-24 Olin Mathieson Water soluble film containing agricultural chemicals
US4144050A (en) 1969-02-05 1979-03-13 Hoechst Aktiengesellschaft Micro granules for pesticides and process for their manufacture
US3920442A (en) 1972-09-18 1975-11-18 Du Pont Water-dispersible pesticide aggregates
US4172714A (en) 1976-12-20 1979-10-30 E. I. Du Pont De Nemours And Company Dry compactible, swellable herbicidal compositions and pellets produced therefrom
GB2095558B (en) 1981-03-30 1984-10-24 Avon Packers Ltd Formulation of agricultural chemicals
BR8600161A (en) 1985-01-18 1986-09-23 Plant Genetic Systems Nv CHEMICAL GENE, HYBRID, INTERMEDIATE PLASMIDIO VECTORS, PROCESS TO CONTROL INSECTS IN AGRICULTURE OR HORTICULTURE, INSECTICIDE COMPOSITION, PROCESS TO TRANSFORM PLANT CELLS TO EXPRESS A PLANTINIDE TOXIN, PRODUCED BY CULTURES, UNITED BY BACILLA
US5180587A (en) 1988-06-28 1993-01-19 E. I. Du Pont De Nemours And Company Tablet formulations of pesticides
EP0374753A3 (en) 1988-12-19 1991-05-29 American Cyanamid Company Insecticidal toxines, genes coding therefor, antibodies binding them, transgenic plant cells and plants expressing these toxines
EP0392225B1 (en) 1989-03-24 2003-05-28 Syngenta Participations AG Disease-resistant transgenic plants
ZW13690A1 (en) 1989-08-30 1990-11-21 Aeci Ltd Active ingredient dosage device
DK0427529T3 (en) 1989-11-07 1995-06-26 Pioneer Hi Bred Int Larval killing lactins and plant insect resistance based thereon
PL167613B1 (en) 1990-03-12 1995-09-30 Du Pont Ater dispersible or water soluble pesticide granules with thermally activated binders
DE69122201T2 (en) 1990-10-11 1997-02-06 Sumitomo Chemical Co Pesticides composition
UA48104C2 (en) 1991-10-04 2002-08-15 Новартіс Аг Dna fragment including sequence that codes an insecticide protein with optimization for corn, dna fragment providing directed preferable for the stem core expression of the structural gene of the plant related to it, dna fragment providing specific for the pollen expression of related to it structural gene in the plant, recombinant dna molecule, method for obtaining a coding sequence of the insecticide protein optimized for corn, method of corn plants protection at least against one pest insect
DE4322211A1 (en) 1993-07-03 1995-01-12 Basf Ag Aqueous, multi-phase, stable ready-to-use formulation for crop protection agents and processes for their preparation
US5530195A (en) 1994-06-10 1996-06-25 Ciba-Geigy Corporation Bacillus thuringiensis gene encoding a toxin active against insects
DE19739982A1 (en) * 1996-12-10 1998-06-18 Bayer Ag Fungicidal active ingredient combinations
NZ511311A (en) 1998-11-17 2002-10-25 Kumiai Chemical Industry Co Pyrimidinylbenzimidazole and triazinylbenzimidazole derivatives useful as agricultural, horticultural bactericides
CA2419029A1 (en) 2000-08-25 2002-02-28 Syngenta Participations Ag Bacillus thuringiensis crystal protein hybrids
US7230167B2 (en) 2001-08-31 2007-06-12 Syngenta Participations Ag Modified Cry3A toxins and nucleic acid sequences coding therefor
AU2002361696A1 (en) 2001-12-17 2003-06-30 Syngenta Participations Ag Novel corn event
WO2004083193A1 (en) 2003-03-17 2004-09-30 Sumitomo Chemical Company, Limited Amide compound and bactericide composition containing the same
DE102004049761A1 (en) * 2004-10-12 2006-04-13 Bayer Cropscience Ag Fungicidal drug combinations
BRPI0519236A2 (en) * 2004-12-23 2009-01-06 Basf Ag fungicidal mixtures, agent, process to combat phytopathogenic harmful fungi, seed, and, use of compounds
BRPI0519235A2 (en) * 2004-12-23 2009-01-06 Basf Ag fungicidal mixtures, agent, process to combat phytopathogenic harmful fungi, seed, and, use of compounds
PE20060801A1 (en) * 2004-12-23 2006-10-03 Basf Ag FUNGICIDE MIXTURES
BRPI0519234A2 (en) * 2004-12-23 2009-01-06 Basf Ag fungicidal mixtures to combat phytopathogenic harmful fungi, agent, process to combat phytopathogenic harmful fungi, seeds, and, use of compounds
TW200738701A (en) 2005-07-26 2007-10-16 Du Pont Fungicidal carboxamides
DE102005057837A1 (en) * 2005-12-03 2007-06-06 Bayer Cropscience Ag Fungicidal combination of active ingredients
WO2008013622A2 (en) 2006-07-27 2008-01-31 E. I. Du Pont De Nemours And Company Fungicidal azocyclic amides
EP2183969A3 (en) * 2008-10-29 2011-01-05 Basf Se Method for increasing the number of seedlings per number of sowed grains of seed
CN101584330B (en) * 2009-04-15 2012-05-23 陕西蒲城县美邦农药有限责任公司 Propineb and azoxystrobin-containing antiseptic composition
WO2010139653A1 (en) * 2009-06-04 2010-12-09 Basf Se Fungicidal mixtures comprising heteraromatic sulfonamides
CN101703058A (en) * 2009-11-18 2010-05-12 青岛海利尔药业有限公司 germicide composite containing azoxystrobin and propineb
CN101816305A (en) * 2010-05-09 2010-09-01 海南正业中农高科股份有限公司 Bactericide pesticide composite containing oligochitosan

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105309488A (en) * 2014-06-25 2016-02-10 陕西美邦农药有限公司 Bactericidal composition containing polygonum cuspidatum extract and azoxystrobin or kresoxim-methyl
CN105265493A (en) * 2014-06-25 2016-01-27 陕西美邦农药有限公司 Composition comprising polygonum cuspidatum extract
CN105211118A (en) * 2014-06-28 2016-01-06 陕西美邦农药有限公司 A kind of bactericidal composition containing Gentrin Knotweed P.E and ZJ0712 or azoles bacterium ester
CN105309489A (en) * 2014-06-30 2016-02-10 陕西美邦农药有限公司 Bactericidal composition containing polygonum cuspidatum extract and pyraclostrobin
CN105309490A (en) * 2014-07-03 2016-02-10 陕西美邦农药有限公司 Bactericidal composition containing polygonum cuspidatum extract, trifloxystrobin or benzene kresoxim-methyl
CN105309494A (en) * 2014-07-07 2016-02-10 陕西美邦农药有限公司 Sterilization composition containing Rhizoma Polygoni Cuspidati extract and fluoxastrobin or picoxystrobin
CN104286031A (en) * 2014-09-22 2015-01-21 江苏省绿盾植保农药实验有限公司 Biological compound bactericidal composition and application thereof
CN110150306A (en) * 2014-11-05 2019-08-23 江苏龙灯化学有限公司 A kind of active ingredient compositions
CN110150306B (en) * 2014-11-05 2021-12-14 江苏龙灯化学有限公司 Active ingredient composition
CN104770398A (en) * 2015-01-28 2015-07-15 中国水稻研究所 Biocontrol bacterium and trifloxystrobin composition
CN104770398B (en) * 2015-01-28 2018-04-10 中国水稻研究所 A kind of composition of biocontrol bacteria and trifloxystrobin
CN105145602A (en) * 2015-09-25 2015-12-16 安徽美兰农业发展股份有限公司 Pyraclostrobin and propineb compound wettable powder and preparation method thereof
CN106719751A (en) * 2016-11-24 2017-05-31 山东省果树研究所 A kind of apple anthrax leaf blight special sterilizing composition and its application

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