CN104255756B - A kind of bactericidal composition that contains pyraclostrobin and chitosan and application thereof - Google Patents
A kind of bactericidal composition that contains pyraclostrobin and chitosan and application thereof Download PDFInfo
- Publication number
- CN104255756B CN104255756B CN201410458665.7A CN201410458665A CN104255756B CN 104255756 B CN104255756 B CN 104255756B CN 201410458665 A CN201410458665 A CN 201410458665A CN 104255756 B CN104255756 B CN 104255756B
- Authority
- CN
- China
- Prior art keywords
- chitosan
- pyraclostrobin
- bactericidal composition
- contains pyraclostrobin
- dispersant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of bactericidal composition that contains pyraclostrobin and chitosan, described bactericidal composition contains pyraclostrobin and two kinds of active components of chitosan, and wherein the weight ratio of pyraclostrobin and chitosan is 30:1～1:30. The invention also discloses a kind of bactericidal composition that contains pyraclostrobin and chitosan in the application preventing and treating in downy mildew of garpe and Strawberry anthracnose. After the combination of pyraclostrobin of the present invention and chitosan, form the effect of having complementary advantages, existing efficient bacteriostasis, can delaying drug resistance produce, reduce consumption, improves security quality, reduce production costs again.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of agricultural bactericidal composition, especially one contains pyraclostrobinBactericidal composition and application thereof with chitosan.
Background technology
In agricultural production, use chemical agent to prevent and treat, producing resistance is inevitably, and has desinsection, sterilizationThe research and development of active noval chemical compound, cost is high, the cycle is long, does not especially catch up with the speed of disease generation resistance. Adopt and doCarrying out composite with mechanism difference, composite two kinds of compounds with synergistic effect is good selection.
Pyraclostrobin:
Pyraclostrobin sterling is that white is to the tasteless crystalline solid of oldlace; The former medicine rat acute of pyraclostrobin per osLD505000mg/kg, acute through skin LD502000mg/kg, Acute inhalation LC50(4h) > 0.3lmg/L; To lagophthalmos eyeball, skinSkin nonirritant: guinea pig skin sensitization test (STT) result is without sensitization: 3 months sub-chronic feeding tests of rat are maximum without doingWith dosage: male rat is 9.2mg/ (kgd), and female rats is 12.9mg/ (kgd). Three mutagenicity tests:Salmonella reversion test, mouse marrow cell micro nuclear test, Germ cells Chromosome aberration are tested all negative. Having no mutagenesis doesWith, Teratogenicity test has no teratogenesis: 2 years chronic feeding test maximum no-effect doses of rat: male rat is3.4mg/ (kgd), female rats is 4.6mg/ (kgd); Rat, mouse carcinogenic test result have no carcinogenicity.
Pyraclostrobin is New-type wide-spectrum bactericide. The mechanism of action is mitochondrial respiratory inhibitor. Pass through at cytochromesIn synthetic, stop electronics to shift. There is protection, treatment, blade infiltration conduction. Pyraclostrobin missible oil is through field medicineEffect result of the test shows that powdery mildew of cucumber, downy mildew and banana freckle, leaf spot, sclerotiniose etc. are had to good controlEffect. To cucumber, banana safety, have no poisoning and occur.
Chitosan:
Chitosan is white, slightly pearly luster, and chip solid is translucent. Chitosan is cationic polymer,Chemical stability is good, and approximately 185 DEG C of decomposition are nontoxic, and water insoluble and alkali lye, is dissolvable in water sulfuric acid, organic acid (as 1%Acetum) and weakly acidic aqueous solution. Rat acute per os LD50> 5000mg/kg (preparation), rat acute is through skin LD50> 5000mg/kg (preparation).
Chitosan (English common name: chltosan) has another name called chitin, Hai Liyuan, chemical name: N-second phthalein aminoGlucose polymer, molecular formula: (C6H11O4N) n. Chitosan is that a class is extracted from practical insect and marine organismsThe natural cationic polysaccharide of one that chitin obtains through deacetylation, has degradability, well film forming and biologyCompatibility and the biologically active such as antibacterial, antitumor, be widely used in the industries such as medicine, food and chemical industry. In agricultural productionIn, chitosan is a kind of good biogenic crop protection agents, has and induces the function of making object resistance factor, again canInfect and the erosion injury of pernicious gas with the pathogenic bacteria drift in film forming protection air. Chitosan is nontoxic, is toolThere is the biological regulator of fertile medicine double effects; Also be non-toxic and non-pollution thickener, can reduce preparation produce in thickenerEffect.
Summary of the invention
Goal of the invention: produce the defect of resistance problem in order to overcome pyraclostrobin and chitosan single dose, the invention providesThe one that a kind of delaying drug resistance produces, reduces consumption, improve security quality, reduce production costs contain pyraclostrobin andThe bactericidal composition of chitosan. The present invention also provides the application of above-mentioned bactericidal composition.
Technical scheme: for solving the problems of the technologies described above, the invention provides a kind of pyraclostrobin and chitosan of containingBactericidal composition, described bactericidal composition contains pyraclostrobin and two kinds of active components of chitosan, wherein pyrazoles ether bacteriumThe weight ratio of ester and chitosan is 30:1～1:30.
Wherein, above-mentioned bactericidal composition also comprises other auxiliary agents and filler.
Wherein, the weight ratio of above-mentioned pyraclostrobin and chitosan is 20:1～1:5.
Wherein, to account for the percentage by weight of bactericidal composition be 6～42% for above-mentioned pyraclostrobin and chitosan.
Wherein, the formulation of above-mentioned bactericidal composition is the one in wettable powder, missible oil, suspending agent or water dispersible granules.
Wherein, above-mentioned auxiliary agent be cornstarch, sodium lignin sulfonate, octyl phenol polyglycol ether, xanthans, ethylene glycol,Dodecyldimethylammonium hydroxide inner salt, dispersing agent NNO, perfluoroalkyl ethyoxyl ether alcohol, azone, potassium dihydrogen phosphate, low gettingFor hydroxypropyl cellulose, dispersant D9, polyvinylpyrrolidone, dispersant D-425, neopelex, recessedOne or more in protruding rod soil, hydroxypropyl cellulose, urea.
Wherein, above-mentioned filler is water, bentonite, white carbon or kaolin.
Above-mentioned a kind of bactericidal composition that contains pyraclostrobin and chitosan is being prevented and treated downy mildew of garpe and strawberry charcoalApplication in subcutaneous ulcer disease.
Beneficial effect: after the combination of pyraclostrobin of the present invention and chitosan, form the effect of having complementary advantages, existingBacteriostasis efficiently, can delaying drug resistance produce, reduce consumption, improves security quality, reduce production costs again.
Detailed description of the invention
Embodiment 1
6.2% pyraclostrobin chitosan water dispersible granules, takes each component raw material according to following proportioning:
Reagent agent:
Said components is mixed, through pulverizing the female powder of preparation, female powder is mixed with suitable quantity of water solution, then squeezePress granulation, dry, analytical control warehouse-in obtains the water dispersible granules of 6.2% pyraclostrobin chitosan.
Embodiment 2
6.3% pyraclostrobin chitosan suspending agent, takes each component raw material according to following proportioning:
By the suspending agent that said components mixes, sand milling, analytical control warehouse-in obtains 6.3% pyraclostrobin chitosan.
Embodiment 3
6% pyraclostrobin chitosan wettable powder, takes each component raw material according to following proportioning:
Said components is mixed, and process is crushed to suitable fineness, analytical control warehouse-in obtains 6% pyraclostrobin and chitin is poly-The wettable powder of sugar.
Embodiment 4
33% pyraclostrobin chitosan water dispersible granules, takes each component raw material according to following proportioning:
Said components is mixed, through pulverizing the female powder of preparation, female powder is mixed with suitable quantity of water solution, then flowChange a bed granulation, dry, screening, analytical control warehouse-in obtain the water dispersible granules of 33% pyraclostrobin and chitosan.
Embodiment 5
42% pyraclostrobin chitosan suspending agent takes each component raw material according to following proportioning:
By the suspending agent that said components mixes, sand milling, analytical control warehouse-in obtains 42% pyraclostrobin chitosan.
Embodiment 6
42% pyraclostrobin chitosan water dispersible granules takes each component raw material according to following proportioning
Said components is mixed, through pulverizing the female powder of preparation, female powder is mixed with suitable quantity of water solution, then flowChange a bed granulation, dry, screening, analytical control warehouse-in obtain the water dispersible granules of 42% pyraclostrobin and chitosan.
Embodiment 7
31% pyraclostrobin chitosan water dispersible granules, takes each component raw material according to following proportioning:
Said components is mixed, through pulverizing the female powder of preparation, female powder is mixed with suitable quantity of water solution, then flowChange a bed granulation, dry, screening, analytical control warehouse-in obtain the water dispersible granules of 31% pyraclostrobin and chitosan.
Experimental example 1:
This experimental example is field efficacy Application Example.
Pyraclostrobin and chitosan series proportioning are prevented and treated downy mildew of garpe and Strawberry anthracnose field control effectiveness test.
1, test is processed: this experimental pharmacy dosage is according to table 1, and contrast medicament is respectively commercially available 25% pyraclostrobin breastOil and 2% chitosan aqua. Blank is tested with clear water.
2, processing method: trial zone is at downy mildew of garpe, Strawberry anthracnose early stage
3,, in trial zone and clear area (CK), choose at random 50 of Different sites of leaf investigation.
4, divide sick level according to the percentage of the shared whole organ of scab (blade, petiole, the stem of crawling) area:
0 grade: without scab;
1 grade: lesion area accounts for below 5% of whole organ area;
3 grades: lesion area accounts for 6%～25% of whole organ area;
5 grades: lesion area accounts for 26%～50% of whole organ area;
7 grades: lesion area accounts for 51%～75% of whole organ area;
9 grades: lesion area accounts for the more than 75% of whole organ area.
5, drug effect is calculated
Disease index=[∑ (the sick number of sheets × relative level numerical value at different levels)/investigate the total number of sheets × 9] × 100
Prevention effect (%)=[1-(contrast disease index × medicine post processing disease index before medicine)/(contrast disease index × medicine after medicinePre-treatment disease index)] × 100
Pyraclostrobin and the chitosan field test results table to downy mildew of garpe, Strawberry anthracnose
Can be found out by result of the test in table, the prevention effect of the complex preparation embodiment of pyraclostrobin and chitosan is equalBe better than single dose, therefore, the weight ratio that pyraclostrobin and chitosan are accumulated shared preparation is 30:1～1:30, more excellent heavyAmount is than being 20:1～1:5. Pyraclostrobin of the present invention and chitosan composition are to downy mildew of garpe, Strawberry anthracnoseThere is good prevention effect, and fungicidal spectrum spectrum is wide, effect is remarkable, cost is low, has reached the object of expection.
The above is only the preferred embodiment of the present invention, is noted that for those skilled in the art,Under the premise without departing from the principles of the invention, can also make some improvements and modifications, these improvements and modifications also should be considered asProtection scope of the present invention.
Claims (5)
1. a bactericidal composition that contains pyraclostrobin and chitosan, it is characterized in that: described bactericidal composition contains pyraclostrobin and two kinds of active components of chitosan, wherein the weight ratio of pyraclostrobin and chitosan is 20:1～1:5, described bactericidal composition also comprises other auxiliary agents and filler, and the percentage by weight that described pyraclostrobin and chitosan account for bactericidal composition is 6～42%.
2. according to a kind of bactericidal composition that contains pyraclostrobin and chitosan claimed in claim 1, it is characterized in that, the formulation of described bactericidal composition is the one in wettable powder, missible oil, suspending agent or water dispersible granules.
3. a kind of bactericidal composition that contains pyraclostrobin and chitosan according to claim 1, it is characterized in that, described auxiliary agent is one or more in cornstarch, sodium lignin sulfonate, octyl phenol polyglycol ether, xanthans, ethylene glycol, dodecyldimethylammonium hydroxide inner salt, dispersing agent NNO, perfluoroalkyl ethyoxyl ether alcohol, dispersant D9, polyvinylpyrrolidone, dispersant D-425, neopelex, attapulgite, hydroxypropyl cellulose, urea.
4. a kind of bactericidal composition that contains pyraclostrobin and chitosan according to claim 2, is characterized in that, described filler is water, bentonite, white carbon or kaolin.
5. a kind of bactericidal composition that contains pyraclostrobin and chitosan claimed in claim 1 is in the application preventing and treating in downy mildew of garpe and Strawberry anthracnose.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410458665.7A CN104255756B (en) | 2014-09-10 | 2014-09-10 | A kind of bactericidal composition that contains pyraclostrobin and chitosan and application thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410458665.7A CN104255756B (en) | 2014-09-10 | 2014-09-10 | A kind of bactericidal composition that contains pyraclostrobin and chitosan and application thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104255756A CN104255756A (en) | 2015-01-07 |
| CN104255756B true CN104255756B (en) | 2016-05-18 |
Family
ID=52147442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410458665.7A Active CN104255756B (en) | 2014-09-10 | 2014-09-10 | A kind of bactericidal composition that contains pyraclostrobin and chitosan and application thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104255756B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110150306B (en) * | 2014-11-05 | 2021-12-14 | 江苏龙灯化学有限公司 | Active ingredient composition |
| CN104886094B (en) * | 2015-05-26 | 2017-05-24 | 青岛沃林蓝莓果业有限公司 | Ointment applied to pruning wounds of diseased branches of blueberry plants |
| CN105994303B (en) * | 2016-08-12 | 2019-01-18 | 李祥英 | A kind of bactericidal composition containing fluoxastrobin and chitosan |
| CN106889092A (en) * | 2017-05-02 | 2017-06-27 | 芮城华农生物化学有限公司 | Bactericidal composition of the pyraclostrobin-containing with Xinjunan acetate and its application |
| CN107156156A (en) * | 2017-05-15 | 2017-09-15 | 杨新兰 | A kind of bactericidal composition |
| CN108835134A (en) * | 2018-07-24 | 2018-11-20 | 句容市茅山镇介文葡萄专业合作社 | A kind of grape disease pest target pesticide control and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012076563A1 (en) * | 2010-12-08 | 2012-06-14 | Basf Se | Fungicidal mixtures |
| CN102939977A (en) * | 2012-11-26 | 2013-02-27 | 海南正业中农高科股份有限公司 | Sterilization combination containing oligosaccharide and methoxy acrylic ester ingredient |
| CN103392737A (en) * | 2013-07-26 | 2013-11-20 | 海南正业中农高科股份有限公司 | Agricultural composition taking oligosaccharide and sulphur as synergistic components |
-
2014
- 2014-09-10 CN CN201410458665.7A patent/CN104255756B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012076563A1 (en) * | 2010-12-08 | 2012-06-14 | Basf Se | Fungicidal mixtures |
| CN102939977A (en) * | 2012-11-26 | 2013-02-27 | 海南正业中农高科股份有限公司 | Sterilization combination containing oligosaccharide and methoxy acrylic ester ingredient |
| CN103392737A (en) * | 2013-07-26 | 2013-11-20 | 海南正业中农高科股份有限公司 | Agricultural composition taking oligosaccharide and sulphur as synergistic components |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104255756A (en) | 2015-01-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104255756B (en) | A kind of bactericidal composition that contains pyraclostrobin and chitosan and application thereof | |
| CN103875916B (en) | Chinese herbal medicine type feed mould inhibitor | |
| CN101171919B (en) | Bactericide agent composition containing active ingredient of epoxiconazole | |
| CN102113511B (en) | Sterilization composite containing azoxystrobin and application | |
| CN104137833A (en) | Complex biological fungicide for preventing and treating wheat scab and application thereof | |
| CN102084862B (en) | Insecticidal composition containing ethiprole | |
| CN103651472A (en) | Bactericidal composition containing penthiopyrad | |
| CN101971860A (en) | Insecticidal composition containing dinotefuran and triazophos | |
| CN104255755B (en) | A kind of bactericidal composition containing pyraclostrobin and Wuyiencin and application thereof | |
| CN105918336A (en) | Bactericidal composition containing prothioconazole and prothioconazole | |
| CN104186550A (en) | Sterilizing composition containing pyrimidine nucleoside antibiotics and eugenol and application thereof | |
| CN101940216A (en) | Water dispersible granule compounded by difenoconazole and propineb | |
| CN101601388A (en) | A kind of bactericidal composition that contains Flutriafol and fluorine bacterium azoles | |
| CN103355303A (en) | Bactericidal composition containing picoxystrobin and amino-oligosaccharin, usage and application thereof | |
| CN104186475A (en) | Sterilizing composition containing fluopyram and validamycin and application thereof | |
| CN106614668A (en) | Sterilization composition containing thifluzamide and cinnamic acid | |
| CN106234364A (en) | A kind of kill spiral shell granule with what wood sawdust made main carriers | |
| CN106305779A (en) | Microbicide composition containing benziothiazolinone and copper hydroxide and applications thereof | |
| CN101601386A (en) | The bactericidal composition of a kind of fluorine-containing bacterium azoles and tpn | |
| CN110170064A (en) | A kind of garbage disposal antibacterial deodorant and its preparation process | |
| CN104585180B (en) | A kind of Pesticidal combination of containing pyriminostrobin | |
| CN101617669A (en) | Sterilization composite containing triflumizole and tebuconazole | |
| CN104585176B (en) | A kind of Pesticidal combination of containing pyriminostrobin | |
| CN101601389A (en) | The bactericidal composition of a kind of fluorine-containing bacterium azoles and Difenoconazole | |
| CN103109845B (en) | Sterilization composition containing azoxystrobin and flusilazole and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20160325 Address after: 212400 Zhenjiang city of Jiangsu province Jurong City Huayang town Hongjing Road No. 1 Applicant after: Zhenjiang Institute of Agricultural Sciences, Jiangsu Hilly Region Address before: 212400 Zhenjiang City, Jiangsu Province Hangzhou Ning Jurong City No. 112 Applicant before: Jiangsu Lvdun Plant Protection Pesticide Experiment Co., Ltd. |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180528 Address after: 231622 Feidong Hefei circular economy demonstration garden, Hefei, Anhui Patentee after: Anhui Fengle Agrochemical Co., Ltd. Address before: 212400 1 Hong Jing Road, Huayang Town, Jurong, Zhenjiang, Jiangsu Patentee before: Zhenjiang Institute of Agricultural Sciences, Jiangsu Hilly Region |
|
| TR01 | Transfer of patent right |