CN103252264A - Multichannel liquid sample injector - Google Patents

Multichannel liquid sample injector Download PDF

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Publication number
CN103252264A
CN103252264A CN2013101601788A CN201310160178A CN103252264A CN 103252264 A CN103252264 A CN 103252264A CN 2013101601788 A CN2013101601788 A CN 2013101601788A CN 201310160178 A CN201310160178 A CN 201310160178A CN 103252264 A CN103252264 A CN 103252264A
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China
Prior art keywords
liquid sample
lifting platform
sample injector
support column
multichannel liquid
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CN2013101601788A
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Chinese (zh)
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CN103252264B (en
Inventor
谢伟胜
张科之
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Li Shulan
Qidong Kaierda Electric Appliance Co ltd
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SUZHOU JIENUOMANBO BIOTECHNOLOGY CO Ltd
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Priority to CN201310160178.8A priority Critical patent/CN103252264B/en
Publication of CN103252264A publication Critical patent/CN103252264A/en
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Abstract

The invention discloses a multichannel liquid sample injector which comprises a rack body, a lifting table and a sampling device, wherein the rack body comprises a bottom plate and a pair of support pillars which are symmetrically arranged on the bottom plate; the pair of support pillars respectively pass through holes formed in the lifting table, so that the lifting table can move up and down along the support pillars, and is fixed on the support pillars by lifting locking knobs arranged on the lifting table; the sampling device comprises a funnel-shaped liquid storage groove and an inverted T-shaped liquid discharge channel, wherein the top of the inverted T-shaped liquid discharge channel is communicated with a close up end of the liquid storage groove; a liquid discharge switch is arranged at the part of the liquid storage groove, which is close to the close up end; the bottom of the inverted T-shaped liquid discharge channel is provided with a plurality of sampling needles; and each sampling needle passes through the lifting table and is fixed on the lifting table. The multichannel liquid sample injector can be used for sampling liquid sample into multiple channels at the same time, thus being time-saving and labor-saving, reducing the error and the error probability, and being especially suitable for sampling liquid in a centrifuge tube; and two switches are arranged on the multichannel liquid sample injector, so that the liquid sampling flow speed is effectively controlled, and the different liquids are avoided being mixed when being added into the same tube.

Description

Multichannel liquid sample injector
Technical field
The present invention relates to a kind of sample injector, especially relate to a kind of sample injector a plurality of application of sample passages and that be applicable to the fluid sample application of sample that has.
Background technology
As everyone knows, in the experimentation in fields such as cell biology, molecular biology, microbiology, generally need to adopt tubular containers such as test tube or centrifuge tube to participate in experiment, especially when using centrifuge tube to carry out density gradient centrifugation, usually adopt medium in centrifuge tube, to form continuous or discrete density gradient solution earlier, this medium is generally cesium chloride, sucrose or saccharoSan, clasmatosis suspension or homogenate are placed the top of medium, the effect by gravity or centrifugal force field makes cell layering, separation again.In this operating process, the bottom to centrifuge tube adds above-mentioned medium earlier, and then carefully adds clasmatosis suspension or homogenate in medium upper surface place slowly.Prior art generally is that single channel namely adopts single teat glass or stainless steel needle tubing single to carry out application of sample; so not only waste time and energy; inefficiency and be difficult to repeatedly many application of samples that carry out simultaneously in batches; and error or error appear in manual operations easily; especially as in twice application of sample process of above-mentioned medium and clasmatosis suspension front and back; usually can mix mutually with clasmatosis suspension contact-making surface owing to the big or small bad control of application of sample speed and application of sample amount causes medium; thereby cause follow-up cell layering; centrifugal effect is bad; further waste raw material such as cell, influence the experiment process.
Summary of the invention
The objective of the invention is to solve a kind of sample injector of technical problems such as above-mentioned application of sample inefficiency, sum of errors error are bigger, specifically relate to a kind of multichannel of can realizing repeatedly and stablize sample injector application of sample, that be applicable to the fluid sample application of sample.Technical solution of the present invention is:
A kind of multichannel liquid sample injector, comprise passive support body, be installed in lifting platform and the sample adding device that is arranged on the described lifting platform on the described support body, described support body comprises base plate and the symmetrical a pair of support column that is arranged on the described base plate, a pair of described support column passes the hole of offering on the lifting platform respectively, described lifting platform is moved up and down along support column, and be fixed on the described support column by the lifting locking knob that is arranged on the described lifting platform, described sample adding device comprises the funnel-form reservoir, be communicated with the inverted T shape apocenosis passage that reservoir closes up and holds with the top, on described reservoir, be provided with the tapping switch near its closing in end place, be provided with several sample needles in described inverted T shape apocenosis passage bottom, every described sample needle passes described lifting platform and is fixed on the lifting platform.
The present invention further, described sample adding device also comprises the corresponding separatory passage that is arranged between described apocenosis passage and the described sample needle, each described separatory passage is provided with the separatory switch.
The present invention further, described support body also comprises one with the vertically disposed backboard of base plate and is arranged on the fixed head that plays fixation of described backboard upper end, described support column upper end.
The present invention further, described fixed head is the U-type strip plate of aluminum alloy material.
The present invention further, the distance that a pair of described support column branch is clipped to described backboard equates.
The present invention further, described support column is the cylinder of aluminum alloy material or stainless steel.
The present invention comprises at least one described reservoir further.
The present invention further, described reservoir is the transparent or semitransparent cell body of PC material.
The present invention further, described lifting platform is the cuboid of aluminum alloy material.
Beneficial effect of the present invention is mainly reflected in:
1. the present invention can realize fluid sample multichannel application of sample simultaneously, and is time saving and energy saving, reduces sum of errors and reduces the error probability; 2. the present invention especially is fit to the liquid application of sample of centrifuge tube, by the setting of twice switch, effectively controls liquid application of sample flow velocity, avoids different liquids to add and occurs mixing mutually phenomenon in the same pipe.3. the present invention also has the shatter-resistant antidetonation, light firm characteristics.
Description of drawings
Fig. 1 is the structural representation of multi-channel loading device of the present invention.
The specific embodiment
The present invention will be described below in conjunction with accompanying drawing and specific embodiment, for embodiment product of the present invention or method are made the generality illustration, help to understand better the present invention, but can't limit the scope of the invention.Experimental technique described in the following embodiment if no special instructions, is conventional method; Described material if no special instructions, all can obtain from commercial channels.
See also Fig. 1, a kind of multichannel liquid of the present invention sample injector, its agent structure comprises passive support body, be installed in the lifting platform 2 on the described support body and be arranged on sample adding device on the described lifting platform 2, described sample adding device by lifting platform 2 moving up and down on described support body realize the liquid application of sample, sample adding device is in diverse location when finishing different conditions such as application of sample.
Wherein, described support body comprises base plate 11 and the symmetrical a pair of support column 12 that is arranged on the described base plate 11, a pair of described support column 12 passes the hole of offering on the lifting platform 2 respectively, described lifting platform 2 is moved up and down along support column 12, and be fixed on the described support column 12 by the lifting locking knob 21 that is arranged on the described lifting platform 2, the present invention preferably, described support body also comprises one and base plate 11 vertically disposed backboards 13, with be arranged on described backboard 13 upper ends, the fixed head 14 that plays fixation of described support column 12 upper ends, particularly, fixed head 14 is the U-type strip plate of aluminum alloy material, the distance that a pair of described support column was clipped to described backboard 13 in 12 minutes equates, therefore, the integrative-structure of this U-type strip plate can be reinforced the rectangular frame that is connected to form by support column 12 upper ends and backboard 13 upper ends, further make whole frame body structure of the present invention firm, be difficult for rocking.
As shown in Figure 1, sample adding device described in the present invention comprises that funnel-form reservoir 31 and top are communicated with the inverted T shape apocenosis passage 41 that reservoir 31 closes up and holds, on described reservoir 31, near its closing in end place, be provided with tapping switch 32, be provided with several sample needles 44 in described inverted T shape apocenosis passage 41 bottoms, every described sample needle 44 passes described lifting platform 2 and is fixed on the lifting platform 2.Particularly, comprise at least one described reservoir 31, the quantity of reservoir 31 is relevant according to the required fluid sample species number that uses in the application of sample process, in general, the quantity of reservoir 31 is greater than the fluid sample species number, because between different liquids sample pipetting volume process, also need carry out the flushing of sample needle at the reservoir 31 that cleaning fluid is equipped with in use.
The present invention in use is rotatably provided in the lifting locking knob 21 on the described lifting platform 2, lifting platform 2 is risen and adjusts to correct position, and the centrifuge tube shelf 5 that centrifuge tube is housed is placed on the base plate 11, makes the opening part of centrifuge tube aim at sample needle 44 respectively.Then, in the reservoir 31 that is fixed on the apocenosis passage 41, add the fluid sample that is about to carry out application of sample, or behind reservoir 31 interior adding fluid samples, be fixed on again on the apocenosis passage 41 earlier.After being ready to above-mentioned work, by lifting locking knob 21 lifting platform 2 is slowly moved down, the syringe needle that drives sample needle 44 drops in each centrifuge tube, locking lifting locking knob 21, with this moment lifting platform 2 fixed-site on support column 12.At last, can slowly open tapping switch 32, the fluid sample in the reservoir 31 is flow to respectively in each sample needle 44 through inverted T shape apocenosis passage 41, fluid sample is joined in the centrifuge tube.After application of sample finishes, in the time of need carrying out the application of sample of another fluid sample continuously, only need to take out centrifuge tube, add cleaning fluid at reservoir 31, T type apocenosis passage 41 and sample needle are cleaned up repeat aforesaid operations later and get final product.
As shown in Figure 1, sample adding device described in the preferred embodiment of the present invention also can comprise the corresponding separatory passage 42 that is arranged between described apocenosis passage 41 and the described sample needle 44, and each described separatory passage 42 is provided with separatory switch 43.By this design, can better adapt to the requirement of different experiments, design the different sample loading mode that adds.So, can realize fluid sample multichannel application of sample simultaneously by multichannel liquid sample injector of the present invention, time saving and energy saving, reduce sum of errors and reduce the error probability.The present invention especially is fit to the liquid application of sample of centrifuge tube, by the setting of twice switch, effectively controls liquid application of sample flow velocity, avoids different liquids to add and occurs mixing mutually phenomenon in the same pipe.Because described support column 12 makes the present invention have the shatter-resistant antidetonation, light firm characteristics for cylinder, the described reservoir 31 of aluminum alloy material or stainless steel are cuboids of aluminum alloy material for the transparent or semitransparent cell body of PC material, described lifting platform 2.
The above only is preferred embodiment of the present invention; should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the technology of the present invention principle; can also make some improvement and modification, these improve and modification also should be considered as protection scope of the present invention.

Claims (9)

1. multichannel liquid sample injector comprises passive support body, is installed in the lifting platform (2) on the described support body and is arranged on sample adding device on the described lifting platform (2), it is characterized in that:
Described support body comprises base plate (11) and the symmetrical a pair of support column (12) that is arranged on the described base plate (11), a pair of described support column (12) passes the hole of offering on the lifting platform (2) respectively, makes described lifting platform (2) move up and down and be fixed on the described support column (12) by the lifting locking knob (21) that is arranged on the described lifting platform (2) along support column (12);
Described sample adding device comprises that funnel-form reservoir (31) and top are communicated with the inverted T shape apocenosis passage (41) that reservoir (31) closes up and holds, go up at described reservoir (31), be provided with tapping switch (32) near its closing in end place, be provided with several sample needles (44) in described inverted T shape apocenosis passage (41) bottom, every described sample needle (44) passes described lifting platform (2) and is fixed on the lifting platform (2).
2. multichannel liquid sample injector according to claim 1, it is characterized in that: described sample adding device also comprises the corresponding separatory passage (42) that is arranged between described apocenosis passage (41) and the described sample needle (44), and each described separatory passage (42) is provided with separatory switch (43).
3. multichannel liquid sample injector according to claim 1 is characterized in that: described support body also comprises one with the vertically disposed backboard of base plate (11) (13) and is arranged on the fixed head (14) of a fixation of described backboard (13) upper end, described support column (12) upper end.
4. multichannel liquid sample injector according to claim 3, it is characterized in that: described fixed head (14) is the U-type strip plate of aluminum alloy material.
5. multichannel liquid sample injector according to claim 3 is characterized in that: a pair of described support column (12) divides the distance that is clipped to described backboard (13) to equate.
6. multichannel liquid sample injector according to claim 1 is characterized in that: described support column (12) is the cylinder of aluminum alloy material or stainless steel.
7. multichannel liquid sample injector according to claim 1 is characterized in that: comprise at least one described reservoir (3).
8. multichannel liquid sample injector according to claim 1, it is characterized in that: described reservoir (3) is the transparent or semitransparent cell body of PC material.
9. multichannel liquid sample injector according to claim 1, it is characterized in that: described lifting platform (2) is the cuboid of aluminum alloy material.
CN201310160178.8A 2013-05-03 2013-05-03 Multichannel liquid sample injector Active CN103252264B (en)

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CN103252264B CN103252264B (en) 2016-03-30

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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105754840A (en) * 2016-04-22 2016-07-13 常州英德生物科技有限公司 Liquid culture medium subpackaging device
CN107398359A (en) * 2017-06-26 2017-11-28 中国农业科学院农业资源与农业区划研究所 Multifunctional layered instrument and centrifugal liquid layered approach for ultracentrifugation liquid
CN107976553A (en) * 2017-12-18 2018-05-01 置展生物医疗科技(深圳)有限公司 Multi-channel loading mechanical arm
CN108254235A (en) * 2018-01-10 2018-07-06 福州大学 Array sample injector
CN111175090A (en) * 2020-03-12 2020-05-19 徐州蓝湖信息科技有限公司 Liquid sample equant instrument
CN112221545A (en) * 2020-12-10 2021-01-15 天津德祥生物技术有限公司 Multi-channel microfluidic sample adding device and application thereof
CN114324958A (en) * 2022-03-17 2022-04-12 天津德祥生物技术有限公司 Application of sample card and application of sample subassembly

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Publication number Priority date Publication date Assignee Title
US20030107738A1 (en) * 2001-12-12 2003-06-12 Curtis Richard H. Photometric calibration of liquid volumes
CN101596469A (en) * 2009-07-03 2009-12-09 烟台艾德康生物科技有限公司 Multi-channel loading device
CN202207603U (en) * 2011-07-19 2012-05-02 烟台艾德康生物科技有限公司 Gas-liquid replacing and liquid charging pump of automatic sample loading gun
CN203264746U (en) * 2013-05-03 2013-11-06 苏州杰诺曼博生物科技有限公司 Multi-channel liquid sample injector

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030107738A1 (en) * 2001-12-12 2003-06-12 Curtis Richard H. Photometric calibration of liquid volumes
CN101596469A (en) * 2009-07-03 2009-12-09 烟台艾德康生物科技有限公司 Multi-channel loading device
CN202207603U (en) * 2011-07-19 2012-05-02 烟台艾德康生物科技有限公司 Gas-liquid replacing and liquid charging pump of automatic sample loading gun
CN203264746U (en) * 2013-05-03 2013-11-06 苏州杰诺曼博生物科技有限公司 Multi-channel liquid sample injector

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105754840A (en) * 2016-04-22 2016-07-13 常州英德生物科技有限公司 Liquid culture medium subpackaging device
CN105754840B (en) * 2016-04-22 2018-06-26 常州英德生物科技有限公司 Fluid nutrient medium packaging device
CN107398359A (en) * 2017-06-26 2017-11-28 中国农业科学院农业资源与农业区划研究所 Multifunctional layered instrument and centrifugal liquid layered approach for ultracentrifugation liquid
CN107976553A (en) * 2017-12-18 2018-05-01 置展生物医疗科技(深圳)有限公司 Multi-channel loading mechanical arm
CN108254235A (en) * 2018-01-10 2018-07-06 福州大学 Array sample injector
CN108254235B (en) * 2018-01-10 2020-03-17 福州大学 Array type sample injector
CN111175090A (en) * 2020-03-12 2020-05-19 徐州蓝湖信息科技有限公司 Liquid sample equant instrument
CN112221545A (en) * 2020-12-10 2021-01-15 天津德祥生物技术有限公司 Multi-channel microfluidic sample adding device and application thereof
CN112221545B (en) * 2020-12-10 2021-03-16 天津德祥生物技术有限公司 Multi-channel microfluidic sample adding device and application thereof
WO2022121394A1 (en) * 2020-12-10 2022-06-16 天津德祥生物技术有限公司 Multi-channel microfluidic sample adding device, assembly, and use thereof
CN116490281A (en) * 2020-12-10 2023-07-25 天津德祥生物技术股份有限公司 Multichannel microfluidic sample adding device, component and application thereof
CN114324958A (en) * 2022-03-17 2022-04-12 天津德祥生物技术有限公司 Application of sample card and application of sample subassembly

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Effective date of registration: 20151110

Address after: 226251 Jiangsu city of Nantong province Qidong City Yin Yang Town Industrial Park

Applicant after: QIDONG KAIERDA ELECTRIC APPLIANCE CO.,LTD.

Address before: 266000 Shandong province Qingdao city Licang District Road No. 1020 Laoshan two unit 302

Applicant before: Li Shulan

Effective date of registration: 20151110

Address after: 266000 Shandong province Qingdao city Licang District Road No. 1020 Laoshan two unit 302

Applicant after: Li Shulan

Address before: Suzhou City, Jiangsu Province, Suzhou Industrial Park 215123 Xinghu Street No. 218 Biological Park A2-310

Applicant before: SUZHOU TIB BIOTECHNOLOGY Co.,Ltd.

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