CN201020402Y - Detachable utility type magnetic separating rack - Google Patents
Detachable utility type magnetic separating rack Download PDFInfo
- Publication number
- CN201020402Y CN201020402Y CNU2006200492721U CN200620049272U CN201020402Y CN 201020402 Y CN201020402 Y CN 201020402Y CN U2006200492721 U CNU2006200492721 U CN U2006200492721U CN 200620049272 U CN200620049272 U CN 200620049272U CN 201020402 Y CN201020402 Y CN 201020402Y
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- CN
- China
- Prior art keywords
- magnetic
- detachable
- model
- utility
- main frame
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/025—High gradient magnetic separators
- B03C1/031—Component parts; Auxiliary operations
- B03C1/033—Component parts; Auxiliary operations characterised by the magnetic circuit
- B03C1/0332—Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L9/00—Supporting devices; Holding devices
- B01L9/06—Test-tube stands; Test-tube holders
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/28—Magnetic plugs and dipsticks
- B03C1/288—Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C1/00—Magnetic separation
- B03C1/02—Magnetic separation acting directly on the substance being separated
- B03C1/30—Combinations with other devices, not otherwise provided for
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
- B01L2200/0652—Sorting or classification of particles or molecules
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
- B03C2201/00—Details of magnetic or electrostatic separation
- B03C2201/26—Details of magnetic or electrostatic separation for use in medical applications
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- Health & Medical Sciences (AREA)
- Clinical Laboratory Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Centrifugal Separators (AREA)
Abstract
A dismountable practical type magnetic knock-out bracket, which belongs to the biomedical technical field, comprises a main frame and a dismountable type magnetic plate. The main frame is composed of an upper base, a lower base, a left base and a right base, and a chute, in which the dismountable type magnetic plate is inserted, is arranged between the upper and the lower bases. Compared with the known magnetic separator, the utility model is provided with simple structure, practicality and convenience. Moreover, the utility model can be used as a normal knock-out bracket and magnetic knock-out bracket simultaneously, and can separate centrifuge tubes with various volumes. By using the utility model, the convenience and practicality of the magnetic separation operating process are promoted, the multi-purpose bracket is realized, the using cost is reduced and the working efficiency is improved.
Description
Technical field
The utility model relates to a kind of device of field of biomedicine technology, specifically is the practical magnetic separation rack of a kind of detachable.
Background technology
The application of magnetic separation technique in the separating of cell biology, immunology, acology, diagnostics and pharmacy etc. more and more widely, for example protein and enzyme is fixing, immunoassay, the purifying of RNA and DNA, cell separation and pharmaceutical carrier or the like.Compare with separation method such as the precipitation method, centrifugal process, ion-exchange and various chromatography methods commonly used, convenient and swift, characteristics such as equipment needed thereby is simple, separating rate is fast, extraction efficiency height that magnetic separation technique has, help keeping advantages such as properties of samples, particularly biologically active.
The magnetic separator frame is a kind of magnetic separating apparatus simple in structure, easy to use.The biomagnetism isolation technics of nano magnetic particle needs will have by externally-applied magnetic field the biomolecule absorption of magnetic mark in application.The centrifuge tube that sample and magnetic material will be housed during use is usually put into magnetic separator frame sample well, magnetic material in the sample can be enriched in the tube wall near magnetic separator frame one side under the effect of externally-applied magnetic field, with pipettor or aspiration pump liquid is siphoned away then and can realize separating of magnetic material and fluid sample.
Various types of magnetic separation rack specificitys are stronger on the existing market, the magnetic separation rack of general a kind of model only is applicable to that a kind of centrifuge tube of volume specification uses, so in use just restricted to the volume and the separation container of sample, and the consumer will increase use cost at the different different magnetic separator frames of sample volume outfit.In addition, the magnetic separating plate of existing magnetic separator frame product generally connects together with separator frame, when the consumer carries out the separation of a plurality of samples at the same time like this, will after separating end, repeatedly wash each magnetic, constantly repeat from the magnetic separator frame, to pipette the operation of centrifuge tube during operations such as wash-out, increased the inconvenience and the operating time of operating process to other rack for test tubes.
Summary of the invention
The purpose of this utility model is to overcome the not strong and not strong problem of practicality of existing magnetic separation rack versatility, provides a kind of simple in structure, easy and simple to handle, is fit to the practical magnetic separation rack of detachable that multiple volume centrifuge tube uses.
The utility model is achieved through the following technical solutions, and the utility model comprises: main frame and in be provided with the detachable magnetic sheet of magnet.Main frame is surrounded by top base, bottom base, left pedestal, right pedestal, is provided with chute in the centre of described top base, bottom base, can insert the detachable magnetic sheet in the chute.Wherein, respectively be provided with the hole that at least one diameter is 10.5 ± 0.1mm in the chute both sides of described top base.In a side of described left pedestal, right pedestal the hole of diameter 28mm and diameter 16mm is arranged, be used for placing when edge-on the centrifuge tube of 50ml and 15ml.
Described detachable magnetic sheet can be the magnet plate of ndfeb magnet, electromagnet, alnico magnetic material making, or is a monoblock or several magnet plates that magnet plate is spliced.
When carrying out Magnetic Isolation, in the middle of bottom base chute on the detachable magnetic sheet insertion main frame.Under the effect of magnetic field, the magnetic-particle in the centrifuge tube all is adsorbed on a side in close magnetic field in the centrifuge tube.With liquid-transfering gun or vacuum air pump supernatant is extracted out, can be finished separation.After separating end, the detachable magnetic sheet is extracted out the bottom base chute from main frame, promptly be can be used as common rack for test tube and carry out subsequent operation.
The present utility model has following advantage: (1) is simple and easy to usefulness, can simplify the operation course, and increases work efficiency.The magnetic separator frame that the utility model provides can use as magnetic separator frame and common non magnetic rack for test tube simultaneously by control detachable magnetic sheet.Use is simple to operate, and is convenient, needn't be after each goes on foot lock out operation mobile centrifuge tube and directly on same shelf, carry out subsequent operation, simplified operating process greatly, thereby improved operating efficiency.(2) be applicable to the centrifuge tube of multiple different volumes simultaneously.Can be suitable for the 1.5ml of smaller size smaller and the centrifuge tube of 2.0ml, also go for the 15ml and the 50ml centrifuge tube of large volume.(3) can be used for the lock out operation of a plurality of samples simultaneously.
The utility model device is simple and easy to usefulness, can be applicable to the centrifuge tube (1.5-50ml) of multiple volume simultaneously, has improved the versatility of magnetic separation rack; Have simultaneously the function of magnetic separation rack and common rack for test tube again concurrently, realized " using one " more, reduced use cost, improved operating efficiency.
Description of drawings
Fig. 1 is the structural representation of magnetic separator frame of the present utility model.
Fig. 2 is the schematic diagram of each base assembly of main frame in the magnetic separator frame of the present utility model.
Fig. 3 is the generalized section of top base, bottom base in the magnetic separator frame of the present utility model.
The specific embodiment
Below embodiment of the present utility model is elaborated: present embodiment is being to implement under the prerequisite with technical solutions of the utility model; provided detailed embodiment and concrete operating process, but protection domain of the present utility model is not limited to following embodiment.
Magnetic Nano material is an example with the liquid sample that contains nucleic acid in the 1.5ml centrifuge tube to separate:
As shown in Figure 1 and Figure 2, present embodiment is made up of main frame 1 and detachable magnetic sheet 2.Main frame 1 is surrounded by top base 3, bottom base 4 and left pedestal 5, right pedestal 6.There is chute 7 (Fig. 3) centre of bottom base 3,4, the interior detachable magnetic sheet 2 that inserts on described.Wherein, respectively be provided with the hole that at least more than one diameter is 10.5 ± 0.1mm, can carry out separating of a plurality of 1.5ml and 2.0ml centrifuge tube simultaneously in chute 7 both sides of described top base 3.Be provided with the hole of diameter 16mm and 28mm diameter in a side of described left and right sides pedestal 5,6, be used for placing when edge-on the centrifuge tube of 15ml and 50ml.
With left and right sides pedestal 5,6 in porose same side is set, the outer rim of described detachable magnetic sheet 2 is provided with a hole, diameter can be between 12-40mm.During use, the centrifuge tube that magnetic-particle and sample are housed is positioned in the hole of top base 3, one refers to fasten detachable magnetic sheet 2 outer edge side apertures then, and detachable magnetic sheet 2 is pushed in the main frame 1 along chute.Magnetic-particle in the centrifuge tube or the magnetic material that is adsorbed with nucleic acid are inhaled then and are gone can finish separation process after the supernatant being adsorbed on centrifugal tube wall under the effect of externally-applied magnetic field near on that side in magnetic field.Detachable magnetic sheet 2 is extracted out from main frame 1, centrifuge tube promptly can be placed on and repeatedly wash on the same separator frame and operation such as wash-out, can repeat the Magnetic Isolation operating procedure again after inserting detachable magnetic sheet 2 again.
The present utility model is particularly suitable for applied magnetic nano material separation and Extraction nucleic acid, in addition, also can be applied to protein, the Magnetic Isolation of other biological molecules such as cell.
Claims (5)
1. practical magnetic separation rack of detachable, comprise: main frame, detachable magnetic sheet, it is characterized in that: described main frame is surrounded by top base, bottom base and left pedestal, right pedestal, is provided with chute in the centre of described upper and lower pedestal, inserts the detachable magnetic sheet in the chute.
2. the practical magnetic separation rack of detachable according to claim 1 is characterized in that the chute both sides of described top base respectively are provided with the hole that at least more than one diameter is 10.5 ± 0.1mm.
3. the practical magnetic separation rack of detachable according to claim 1 is characterized in that, a side of described left pedestal, right pedestal is respectively equipped with the hole of diameter 28mm and diameter 16mm, is used for placing when edge-on the centrifuge tube of 50ml and 15ml.
4. according to claim 1 or the practical magnetic separation rack of 4 described detachables, it is characterized in that the outer rim of described detachable magnetic sheet is provided with a hole, this bore dia is between 12-40mm.
5. according to claim 1 or the practical magnetic separation rack of 4 described detachables, it is characterized in that described detachable magnetic sheet is the magnet plate of ndfeb magnet, electromagnet, alnico magnetic material making, or be a monoblock magnet plate, or several magnet plates that magnet plate is spliced.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2006200492721U CN201020402Y (en) | 2006-12-21 | 2006-12-21 | Detachable utility type magnetic separating rack |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2006200492721U CN201020402Y (en) | 2006-12-21 | 2006-12-21 | Detachable utility type magnetic separating rack |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201020402Y true CN201020402Y (en) | 2008-02-13 |
Family
ID=39087809
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2006200492721U Expired - Lifetime CN201020402Y (en) | 2006-12-21 | 2006-12-21 | Detachable utility type magnetic separating rack |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN201020402Y (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102417902A (en) * | 2011-09-16 | 2012-04-18 | 广西出入境检验检疫局检验检疫技术中心 | Kit for extracting nucleic acid by magnetic bead-microtiter plate method and method for extracting nucleic acid by same |
| CN103667049A (en) * | 2013-11-30 | 2014-03-26 | 成都欣华源科技有限责任公司 | Magnetic separation tool |
| CN105916972A (en) * | 2013-12-09 | 2016-08-31 | 株式会社百奥尼 | Magnetic particle separating device, and method of separating and purifying nucleic acid or protein using same |
| CN109277980A (en) * | 2018-10-16 | 2019-01-29 | 孔子龙 | A kind of reversed magnetic moment device of separation |
-
2006
- 2006-12-21 CN CNU2006200492721U patent/CN201020402Y/en not_active Expired - Lifetime
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102417902A (en) * | 2011-09-16 | 2012-04-18 | 广西出入境检验检疫局检验检疫技术中心 | Kit for extracting nucleic acid by magnetic bead-microtiter plate method and method for extracting nucleic acid by same |
| CN103667049A (en) * | 2013-11-30 | 2014-03-26 | 成都欣华源科技有限责任公司 | Magnetic separation tool |
| CN105916972A (en) * | 2013-12-09 | 2016-08-31 | 株式会社百奥尼 | Magnetic particle separating device, and method of separating and purifying nucleic acid or protein using same |
| CN105916972B (en) * | 2013-12-09 | 2018-12-21 | 株式会社百奥尼 | The separation and method of purification of magnetic particle separator and nucleic acid or protein using the device |
| CN109277980A (en) * | 2018-10-16 | 2019-01-29 | 孔子龙 | A kind of reversed magnetic moment device of separation |
| CN109277980B (en) * | 2018-10-16 | 2021-04-30 | 孔子龙 | Reverse magnetic moment separating device |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term |
Granted publication date: 20080213 |
|
| EXPY | Termination of patent right or utility model |