CN103232405A - 一种新头孢侧链中间体的合成方法 - Google Patents
一种新头孢侧链中间体的合成方法 Download PDFInfo
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- CN103232405A CN103232405A CN2013101571532A CN201310157153A CN103232405A CN 103232405 A CN103232405 A CN 103232405A CN 2013101571532 A CN2013101571532 A CN 2013101571532A CN 201310157153 A CN201310157153 A CN 201310157153A CN 103232405 A CN103232405 A CN 103232405A
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Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105585539A (zh) * | 2015-12-21 | 2016-05-18 | 山东金城医药化工股份有限公司 | 一锅法合成头孢他啶侧链酸乙酯的方法 |
CN105601510A (zh) * | 2015-12-21 | 2016-05-25 | 山东金城医药化工股份有限公司 | 利用阳离子交换树脂催化合成α-溴代异丁酸叔丁酯的方法 |
CN113372292A (zh) * | 2021-06-29 | 2021-09-10 | 山东昌邑四方医药化工有限公司 | 头孢他啶侧链酸的制备方法 |
CN114805394A (zh) * | 2022-05-27 | 2022-07-29 | 山东普洛得邦医药有限公司 | 一种头孢克肟的合成方法 |
CN115260213A (zh) * | 2022-05-27 | 2022-11-01 | 山东普洛得邦医药有限公司 | 一种头孢地尼的合成方法 |
Citations (3)
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US6214997B1 (en) * | 1998-06-01 | 2001-04-10 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline (Z)-2-(2-tert.-butoxycarbonylprop-2-oxyimino)-2-(2-triphenylmethylaminothiazol-4-yl) acetic acid in association with N,N-dimethylformamide |
CN102452999A (zh) * | 2010-10-25 | 2012-05-16 | 许婧 | 一种头孢他啶中间体的合成工艺 |
CN102516198A (zh) * | 2011-11-22 | 2012-06-27 | 太仓市运通化工厂 | 一种头孢他啶侧链酸的合成方法 |
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- 2013-04-28 CN CN201310157153.2A patent/CN103232405B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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US6214997B1 (en) * | 1998-06-01 | 2001-04-10 | Ranbaxy Laboratories Limited | Process for the preparation of crystalline (Z)-2-(2-tert.-butoxycarbonylprop-2-oxyimino)-2-(2-triphenylmethylaminothiazol-4-yl) acetic acid in association with N,N-dimethylformamide |
CN102452999A (zh) * | 2010-10-25 | 2012-05-16 | 许婧 | 一种头孢他啶中间体的合成工艺 |
CN102516198A (zh) * | 2011-11-22 | 2012-06-27 | 太仓市运通化工厂 | 一种头孢他啶侧链酸的合成方法 |
Non-Patent Citations (3)
Title |
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傅德才等: "头孢他啶侧链酸活性硫酯的合成", 《中国医药工业杂志》 * |
吴春雁等: "新法合成头孢他定中间产品", 《黑龙江医药》 * |
项宗伟等: "酸烯加成酯化制备丙烯酸叔丁酯的进展与研究", 《化工中间体》 * |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105585539A (zh) * | 2015-12-21 | 2016-05-18 | 山东金城医药化工股份有限公司 | 一锅法合成头孢他啶侧链酸乙酯的方法 |
CN105601510A (zh) * | 2015-12-21 | 2016-05-25 | 山东金城医药化工股份有限公司 | 利用阳离子交换树脂催化合成α-溴代异丁酸叔丁酯的方法 |
CN113372292A (zh) * | 2021-06-29 | 2021-09-10 | 山东昌邑四方医药化工有限公司 | 头孢他啶侧链酸的制备方法 |
CN114805394A (zh) * | 2022-05-27 | 2022-07-29 | 山东普洛得邦医药有限公司 | 一种头孢克肟的合成方法 |
CN115260213A (zh) * | 2022-05-27 | 2022-11-01 | 山东普洛得邦医药有限公司 | 一种头孢地尼的合成方法 |
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