CN102946862A - 含有肝素的局部药物组合物 - Google Patents
含有肝素的局部药物组合物 Download PDFInfo
- Publication number
- CN102946862A CN102946862A CN2011800292644A CN201180029264A CN102946862A CN 102946862 A CN102946862 A CN 102946862A CN 2011800292644 A CN2011800292644 A CN 2011800292644A CN 201180029264 A CN201180029264 A CN 201180029264A CN 102946862 A CN102946862 A CN 102946862A
- Authority
- CN
- China
- Prior art keywords
- heparin
- preparation
- fistula
- graft
- polyalkylene oxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
时间(月) | 溶液ViatrombTM | 溶液A | 抗血小板药 |
1 | 19/20 | 19/20 | 18/20 |
3 | 18/20 | 19/20 | 17/20 |
6 | 18/20 | 19/20 | 16/20 |
Claims (13)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2010A000816 | 2010-05-07 | ||
ITMI2010A000816A IT1400232B1 (it) | 2010-05-07 | 2010-05-07 | Composizione farmaceutica topica comprendente eparina |
US34762610P | 2010-05-24 | 2010-05-24 | |
US61/347,626 | 2010-05-24 | ||
PCT/EP2011/056931 WO2011138262A1 (en) | 2010-05-07 | 2011-05-02 | Topical pharmaceutical composition comprising heparin |
Publications (1)
Publication Number | Publication Date |
---|---|
CN102946862A true CN102946862A (zh) | 2013-02-27 |
Family
ID=43567710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2011800292644A Pending CN102946862A (zh) | 2010-05-07 | 2011-05-02 | 含有肝素的局部药物组合物 |
Country Status (17)
Country | Link |
---|---|
US (1) | US20130102564A1 (zh) |
EP (1) | EP2566457A1 (zh) |
JP (1) | JP2013525505A (zh) |
KR (1) | KR20130054286A (zh) |
CN (1) | CN102946862A (zh) |
AR (1) | AR082653A1 (zh) |
AU (1) | AU2011250005B2 (zh) |
BR (1) | BR112012028434A2 (zh) |
CA (1) | CA2798116A1 (zh) |
CL (1) | CL2012003090A1 (zh) |
EA (1) | EA026568B1 (zh) |
IL (1) | IL222790A0 (zh) |
IT (1) | IT1400232B1 (zh) |
MX (1) | MX2012012930A (zh) |
NZ (1) | NZ603476A (zh) |
WO (1) | WO2011138262A1 (zh) |
ZA (1) | ZA201208949B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106163498A (zh) * | 2014-02-10 | 2016-11-23 | 特罗伊卡药品有限公司 | 肝素的局部制剂 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120009136A1 (en) * | 2010-07-09 | 2012-01-12 | The Dial Corporation | Antiperspirant products comprising natural phospholipids and methods for manufacturing the same |
PL229532B1 (pl) * | 2014-05-29 | 2018-07-31 | Lipolek Spolka Z Ograniczona Odpowiedzialnoscia | Żelowy preparat soli sodowej heparyny do podawania naskórnego |
Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000133A1 (de) * | 1977-06-17 | 1979-01-10 | Ciba-Geigy Ag | Pharmazeutische Präparate mit einem Gehalt an sulfatierten Polysacchariden oder Polymeren und Zinkionen zur topischen Behandlung von Virusinfektionen. |
US5620687A (en) * | 1993-02-25 | 1997-04-15 | Zymogenetics, Inc. | Inhibition of intimal hyperplasia using antibodies to PDGF beta receptors |
CN1238693A (zh) * | 1996-11-27 | 1999-12-15 | 罗纳·布朗克罗尔药制品有限公司 | 含有抗-Xa活性化合物和血小板聚集拮抗化合物的药物组合物 |
WO2002064148A2 (en) * | 2001-02-16 | 2002-08-22 | Shimizu Pharmaceutical Co., Ltd. | Oral formulations containing mucopolysaccharide for small intestine delivery and their use in the treatment circulatory disorders |
WO2002083086A1 (en) * | 2001-04-17 | 2002-10-24 | Cristália Produtos Químicos e Farmacêuticos Ltda. | Pharmaceutical compositions of topic use, applied in treatment of skin and/or mucous injuries; use of compositions in treatment of skin and/or mucous injuries and use of compounds in treatment of skin and/or mucous injuries |
CN1378472A (zh) * | 1999-03-11 | 2002-11-06 | 杜邦药品公司 | 通过低分子量肝素与血小板聚集抑制剂间协同作用防治各种血栓栓塞疾病的联合治疗方法 |
CN1492759A (zh) * | 2001-01-16 | 2004-04-28 | Ѫ�������������ι�˾ | 预防或治疗血液透析中血管通路和其它血管移植物故障的装置及方法 |
US20050136103A1 (en) * | 2003-09-17 | 2005-06-23 | Ben-Sasson Shmuel A. | Compositions capable of facilitating penetration across a biological barrier |
US20060251713A1 (en) * | 2002-02-07 | 2006-11-09 | Chiasma, Inc. | Amino acid sequences capable of facilitating penetration across a biological barrier |
WO2010029374A1 (en) * | 2008-09-12 | 2010-03-18 | Critical Pharmaceuticals Limited | Improvements in the absorption of therapeutic agents across mucosal membranes or the skin |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0704206B1 (de) | 1994-09-30 | 2002-09-04 | MIKA Pharma Gesellschaft für die Entwicklung und Vermarktung pharmazeutischer Produkte mbH | Pharmazeutische Zusammensetzung |
US5668119A (en) | 1996-02-22 | 1997-09-16 | Medenica; Rajko D. | Topical pharmaceutical containing heparin and method of treatment |
US8152750B2 (en) | 2003-09-12 | 2012-04-10 | Marine Polymer Technologies, Inc. | Vascular access preservation in hemodialysis patients |
-
2010
- 2010-05-07 IT ITMI2010A000816A patent/IT1400232B1/it active
-
2011
- 2011-05-02 WO PCT/EP2011/056931 patent/WO2011138262A1/en active Application Filing
- 2011-05-02 JP JP2013509494A patent/JP2013525505A/ja not_active Withdrawn
- 2011-05-02 MX MX2012012930A patent/MX2012012930A/es unknown
- 2011-05-02 KR KR1020127031825A patent/KR20130054286A/ko not_active Application Discontinuation
- 2011-05-02 EA EA201291191A patent/EA026568B1/ru not_active IP Right Cessation
- 2011-05-02 CA CA2798116A patent/CA2798116A1/en not_active Abandoned
- 2011-05-02 US US13/696,735 patent/US20130102564A1/en not_active Abandoned
- 2011-05-02 AU AU2011250005A patent/AU2011250005B2/en not_active Ceased
- 2011-05-02 BR BR112012028434A patent/BR112012028434A2/pt not_active IP Right Cessation
- 2011-05-02 CN CN2011800292644A patent/CN102946862A/zh active Pending
- 2011-05-02 NZ NZ603476A patent/NZ603476A/en not_active IP Right Cessation
- 2011-05-02 EP EP11716582A patent/EP2566457A1/en not_active Withdrawn
- 2011-05-06 AR ARP110101566A patent/AR082653A1/es unknown
-
2012
- 2012-11-01 IL IL222790A patent/IL222790A0/en unknown
- 2012-11-06 CL CL2012003090A patent/CL2012003090A1/es unknown
- 2012-11-27 ZA ZA2012/08949A patent/ZA201208949B/en unknown
Patent Citations (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0000133A1 (de) * | 1977-06-17 | 1979-01-10 | Ciba-Geigy Ag | Pharmazeutische Präparate mit einem Gehalt an sulfatierten Polysacchariden oder Polymeren und Zinkionen zur topischen Behandlung von Virusinfektionen. |
US5620687A (en) * | 1993-02-25 | 1997-04-15 | Zymogenetics, Inc. | Inhibition of intimal hyperplasia using antibodies to PDGF beta receptors |
CN1238693A (zh) * | 1996-11-27 | 1999-12-15 | 罗纳·布朗克罗尔药制品有限公司 | 含有抗-Xa活性化合物和血小板聚集拮抗化合物的药物组合物 |
CN1378472A (zh) * | 1999-03-11 | 2002-11-06 | 杜邦药品公司 | 通过低分子量肝素与血小板聚集抑制剂间协同作用防治各种血栓栓塞疾病的联合治疗方法 |
CN1492759A (zh) * | 2001-01-16 | 2004-04-28 | Ѫ�������������ι�˾ | 预防或治疗血液透析中血管通路和其它血管移植物故障的装置及方法 |
WO2002064148A2 (en) * | 2001-02-16 | 2002-08-22 | Shimizu Pharmaceutical Co., Ltd. | Oral formulations containing mucopolysaccharide for small intestine delivery and their use in the treatment circulatory disorders |
WO2002083086A1 (en) * | 2001-04-17 | 2002-10-24 | Cristália Produtos Químicos e Farmacêuticos Ltda. | Pharmaceutical compositions of topic use, applied in treatment of skin and/or mucous injuries; use of compositions in treatment of skin and/or mucous injuries and use of compounds in treatment of skin and/or mucous injuries |
US20060251713A1 (en) * | 2002-02-07 | 2006-11-09 | Chiasma, Inc. | Amino acid sequences capable of facilitating penetration across a biological barrier |
US20050136103A1 (en) * | 2003-09-17 | 2005-06-23 | Ben-Sasson Shmuel A. | Compositions capable of facilitating penetration across a biological barrier |
WO2010029374A1 (en) * | 2008-09-12 | 2010-03-18 | Critical Pharmaceuticals Limited | Improvements in the absorption of therapeutic agents across mucosal membranes or the skin |
Non-Patent Citations (1)
Title |
---|
刘金萍等: "低分子质量肝素预防糖尿病肾病动静脉内瘘血栓形成的观察与护理", 《齐鲁医学杂志》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106163498A (zh) * | 2014-02-10 | 2016-11-23 | 特罗伊卡药品有限公司 | 肝素的局部制剂 |
Also Published As
Publication number | Publication date |
---|---|
ITMI20100816A1 (it) | 2011-11-08 |
KR20130054286A (ko) | 2013-05-24 |
CL2012003090A1 (es) | 2014-01-03 |
CA2798116A1 (en) | 2011-11-10 |
IL222790A0 (en) | 2012-12-31 |
AU2011250005B2 (en) | 2015-08-13 |
EP2566457A1 (en) | 2013-03-13 |
BR112012028434A2 (pt) | 2019-09-24 |
NZ603476A (en) | 2014-10-31 |
ZA201208949B (en) | 2013-07-31 |
AR082653A1 (es) | 2012-12-26 |
MX2012012930A (es) | 2013-05-20 |
EA201291191A1 (ru) | 2013-04-30 |
JP2013525505A (ja) | 2013-06-20 |
AU2011250005A1 (en) | 2012-11-29 |
US20130102564A1 (en) | 2013-04-25 |
IT1400232B1 (it) | 2013-05-24 |
WO2011138262A1 (en) | 2011-11-10 |
EA026568B1 (ru) | 2017-04-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
ASS | Succession or assignment of patent right |
Owner name: LAKEDIO PHARMACEUTICALS DEVELOPMENT AND RESTORABIL Free format text: FORMER OWNER: ADVANCE HOLDINGS LTD. Effective date: 20130516 |
|
C10 | Entry into substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
SE01 | Entry into force of request for substantive examination | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20130516 Address after: Austria Klosterneuburg Applicant after: Lectio Pharmaentwicklungs- Und Verwertungs GmbH Address before: Malta Floriana Applicant before: Advance Holdings Ltd. |
|
C05 | Deemed withdrawal (patent law before 1993) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20130227 |