CN102940739A - Chinese medicinal composition for treating vernal keratoconjunctivitis - Google Patents

Abstract

The invention relates to a Chinese medicinal composition for treating vernal keratoconjunctivitis. The Chinese medicinal composition is prepared from the following components of carissa macrocarpa, all-grass of climbing violet, root of Chinese hibiscus, radix clematidis, pepperweed seed, groundsel, pagoda tree fruit, horsetail, cuscuta chinensis, semen plantaginis and borneol. The Chinese medicinal composition for treating the vernal keratoconjunctivitis, disclosed by the invention, can be clinically applied to treating the keratoconjunctivitis.

Description

A kind of Chinese medicine composition for the treatment of keratoconjunctivitis

Technical field

The invention belongs to technical field of Chinese medicines, especially relate to a kind of Chinese medicine composition for the treatment of keratoconjunctivitis.

Background technology

Keratoconjunctivitis is a kind of strong communicable contagious disease, is caused by adenovirus.Onset is anxious, severe symptoms, many eyes morbidities.Cardinal symptom has hyperemia, pain, photophobia and with watery secretion.Fall ill after a couple of days, the infringement of disc of confusion point columnar epithelium appears in cornea.The preauricular lymph nodes enlargement often occurs, and tenderness is arranged.Doctor trained in Western medicine often uses bark ketone or oral quinidine of intravenous injection cedilanid or verapamil, ethamine iodine to control etc., but side effect is very large, and can not effect a radical cure.Drug therapy keratoconjunctivitis of the present invention has reached good effect.

Summary of the invention

The Chinese medicine composition of the treatment keratoconjunctivitis that the object of the present invention is to provide that a kind of therapeutic effect is good, effective percentage is high, human body is had no side effect.

The object of the present invention is achieved like this, according to Chinese medical theory, utilize the property of medicine of Chinese medicine uniqueness, adopt thorn youth fruit, Herba Violae diffusae, Radix Hibisci Rosae-Sinensis, Radix Clematidis, Semen Lepidii (Semen Descurainiae), Herba Senecionis Scandentis, the Fructus Sophorae, Herba Equiseti Hiemalis, Semen Cuscutae, Semen Plantaginis, borneol according to certain compatibility requirement, through being processed into.

Prepare Chinese medicine composition of the present invention and make thorn youth fruit 40-70 part, Herba Violae diffusae 30-50 part, Radix Hibisci Rosae-Sinensis 20-40 part, Radix Clematidis 20-40 part, Semen Lepidii (Semen Descurainiae) 20-40 part, Herba Senecionis Scandentis 20-40 part, Fructus Sophorae 10-30 part, Herba Equiseti Hiemalis 10-30 part, Semen Cuscutae 10-30 part, Semen Plantaginis 10-30 part, borneol 10-30 part by following raw material medicaments.

Optimum weight part of traditional Chinese medicinal composition raw materials of the present invention is: 50 parts of thorn youth fruits, 40 parts of Herba Violae diffusaes, 30 parts of Radix Hibisci Rosae-Sinensiss, 30 parts of Radix Clematidis, 30 parts of Semen Lepidii (Semen Descurainiae)s, 30 parts of Herba Senecionis Scandentiss, 20 parts of the Fructuss Sophorae, 20 parts of Herba Equiseties Hiemalis, 20 parts of Semen Cuscutae, 20 parts of Semen Plantaginiss, 20 parts of borneol.

The pharmacological action of Chinese medicine of the present invention is as follows:

Thorn youth fruit: bitter, hot, flat.Heat-clearing and toxic substances removing, anti-inflammatory analgetic.Be used for icterohepatitis, stomachache, rheumatic arthritis, acute conjunctivitis, pharyngolaryngitis, periodontitis, the diseases such as lymphadenitis.

Herba Violae diffusae: bitter, hot, cold.Return lung, Liver Channel.Heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, cough-relieving.Sore swollen toxin, eye conjunctivitis, cough due to lung-heat, pertussis, icterohepatitis, herpes zoster, burn due to hot liquid or fire, traumatic injury, fracture, the diseases such as venom.

Radix Hibisci Rosae-Sinensis: sweet, puckery, flat.Return liver, spleen, lung meridian.Regulating menstruation, dampness removing, detoxifcation.Be used for menoxenia, metrorrhagia, acute conjunctivitis, leucorrhea, nebulousurine, carbuncle pyogenic infections from tumour or sore, the diseases such as urinary tract infection.

Radix Clematidis: hot, salty, warm.Return urinary bladder channel.Wind-damp dispelling, the meridian dredging, a fishbone or other bone caught in the throat disappears.Be used for rheumatic arthralgia, all bones are choked with sobs etc.Semen Lepidii (Semen Descurainiae): hot, bitter, cold.Return lung, the heart, liver, stomach, urinary bladder channel.The eliminating the pathogens from the lung sending down the abnormal ascending QI, eliminating phlegm and relieving asthma, inducing diuresis to remove edema.Be used for sputum and stop up the dyspnea and cough with excessive sputum of lung, lung abscess, edema, breast abdomen hydrops, dysuria, chronic pulmonary heart disease, breathing heavily of heart failure is swollen, scrofula tuberculosis etc.

Herba Senecionis Scandentis: bitter in the mouth, suffering, cold in nature.Heat-clearing and toxic substances removing, improving acuity of vision and removing nebula, killing parasites for relieving itching.Be used for influenza, upper respiratory tract infection, pneumonia, acute tonsillitis etc.

The Fructus Sophorae: hardship, cold.Cooling blood for hemostasis, liver heat removing and eyesight improving.Be used for bleeding hemorrhoids, discharging fresh blood stool, dysentery, metrorrhagia, stranguria with blood, heat in blood is told nosebleed, poliosis, liver-heat conjunctival congestion, the disease such as have a dizzy spell.

Herba Equiseti Hiemalis: sweetness and bitterness, flat.Return lung, liver, gallbladder meridian.Wind and heat dispersing, cooling blood for hemostasis, improving acuity of vision and removing nebula.Be used for the wind heat conjunctival congestion, order is given birth to nebula, discharging fresh blood stool, hemorrhoidal bleeding, dysentery, married woman's metrorrhagia, proctoptosis etc.

Semen Cuscutae: hot, sweet, put down, return the liver,kidney,spleen warp.The kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the tire stopping leak.Be used for soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst stranguria with turbid discharge, the enuresis etc.

Semen Plantaginis: sweet, cold, return lung, kidney, Liver Channel.Inducing diuresis for treating stranguria syndrome, eliminating dampness by diuresis antidiarrheal, liver heat removing and eyesight improving, removing heat from the lung and dissipating phlegm.It is puckery to be used for urine leaching, diarrhea due to summer heat and dampness, phlegm-heat cough etc.

Borneol: hot, bitter, cool.GUIXIN, lung meridian.The refreshment of having one's ideas straightened out, the heat radiation pain relieving, removing nebula makes eye bright.Be used for the apoplexy locked mouth, calentura coma, infantile convulsion expectorant fan, deafness with qi stagnation, conjunctivitis, sore throat, aphtha, carbuncle, hemorrhoid, enterobiasis etc.

The traditional Chinese medical science thinks that keratoconjunctivitis is outer to be subjected to ailment said due to cold or exposure, priming liver-fire, wind heat is fought mutually, on attack in order.The thorn youth is monarch drug really among the present invention, has heat-clearing and toxic substances removing, the effect of anti-inflammatory analgetic; Herba Violae diffusae, Radix Hibisci Rosae-Sinensis, Radix Clematidis are ministerial drug, have the effect of heat-clearing and toxic substances removing, dampness removing collateral dredging; Semen Lepidii (Semen Descurainiae), Herba Senecionis Scandentis, the Fructus Sophorae, Herba Equiseti Hiemalis, Semen Cuscutae, Semen Plantaginis, borneol have the effect of liver heat removing and eyesight improving, improving acuity of vision and removing nebula.Find that through clinical practice keratoconjunctivitis is had unique curative effect, all medicines are played altogether heat-clearing and toxic substances removing, are dispersed the epidemic disease poison, the effect of promoting blood circulation to remove obstruction in the collateral, dispelling wind nebula removing, reach the purpose for the treatment of keratoconjunctivitis.

Chinese medicine composition of the present invention was in 2008 to 2011 clinical observation keratoconjunctivitis 33 routine patients, and clinical report is as follows:

1, physical data

Among the 33 routine patients, age 17-65 year, the course of disease is many in 1 week to 6 month, 52 years old mean age.

2, diagnostic criteria

2.1 carry out clinical diagnosis with reference to the diagnosis basis in " traditional Chinese medical science disease Standardization of diagnosis and curative effect ":

Hyperemia of the bulbar conjunctiva, or see that subconjunctival ecchymosis is and a little be sheet that born of the same parents' eyelid is red and swollen, the black visible punctate keratitis of eyeball.Can lay one's hand on and examine before the ear or under the chin.Eye is husky puckery, causalgia, and photophobia is shed tears, very person's hot tears such as soup, or a lot of secretion in the eye is rare clearly.

3, Therapeutic Method

3.1 prescription: thorn youth fruit 50g, Herba Violae diffusae 40g, Radix Hibisci Rosae-Sinensis 30g, Radix Clematidis 30g, Semen Lepidii (Semen Descurainiae) 30g, Herba Senecionis Scandentis 30g, Fructus Sophorae 20g, Herba Equiseti Hiemalis 20g, Semen Cuscutae 20g, Semen Plantaginis 20g, borneol 20g.

3.2 method of preparation and use: said medicine routinely technique is made decoction, and 1 dose of every day, every day 2 times, 5 days was 1 course for the treatment of.

4, therapeutic outcome:

4.1 the treatment evaluation criteria, judge according to " traditional Chinese medical science disease Standardization of diagnosis and curative effect " that State Administration of Traditional Chinese Medicine formulates: cure: clinical symptoms and sign all disappear, vision restoration normal (or vision restoration is to premorbid vision);

Produce effects: vision improves, and clinical symptoms and sign all disappear;

Effectively: clinical symptoms and sign all disappear or part disappears or improvement, and vision is without improve;

Invalid: vision without raising or clinical symptoms and sign without taking a turn for the better or increasing the weight of.

4.2 result: among the 33 routine patients, cure 20 examples (60.7%), produce effects is imitated 10 examples (30.3%), effectively imitates 3 examples (9%), invalid 0 example, and total effective rate is 100%.

Model case

1, Wang, the man, 39 years old, right eye was red red, and photophobia pain is shown effect more than the moon repeatedly, examines and sees that right eye is red red, and photophobia is shed tears, and blurred vision is made constipation when bitter taste, headache.Red tongue, thick, yellow and greasy fur, stringy pulse is number slightly.Check: hyperemia of the bulbar conjunctiva, black eyeball central authorities and periphery have the punctate opacity of the cornea of several Semen Sesami sizes.Vision: right eye 0.12, left eye 1.2 is examined and is keratoconjunctivitis.Taking medicine, above-mentioned symptom alleviates after rear 2 courses for the treatment of, and eye is red redly slightly to go down, and checks that right vision promotes to 0.8.Continue to take medicine of the present invention, after 1 course for the treatment of, transference cure is followed up a case by regular visits to after 1 year without recurrence.

2, grandson, the woman, 33 years old, eyes are red, bitterly, shed tears, existing with headache, heating.Check: binocular vision is 1.0, the Dual-eyelid mild swelling, and palpebral conjunctiva is obviously congested, and lower eyelid fornix section has folliculus to form, and cornea of left eye has point-like inflammatory infiltration, red tongue, thick, yellow and greasy fur.Take 1 course for the treatment of of medicine of the present invention, 1 dose of every day, transference cure is followed up a case by regular visits to after 1 year without recurrence.

The specific embodiment

The present invention is further illustrated below in conjunction with embodiment, and following this embodiment only for explanation the present invention to the present invention without limits.

Embodiment 1, a kind of Chinese medicine composition for the treatment of keratoconjunctivitis is to be made by thorn youth fruit 40g, Herba Violae diffusae 30g, Radix Hibisci Rosae-Sinensis 20g, Radix Clematidis 20g, Semen Lepidii (Semen Descurainiae) 20g, Herba Senecionis Scandentis 20g, Fructus Sophorae 10g, Herba Equiseti Hiemalis 10g, Semen Cuscutae 10g, Semen Plantaginis 10g, borneol 10g.

Embodiment 2, a kind of Chinese medicine composition for the treatment of keratoconjunctivitis is to be made by thorn youth fruit 50g, Herba Violae diffusae 40g, Radix Hibisci Rosae-Sinensis 30g, Radix Clematidis 30g, Semen Lepidii (Semen Descurainiae) 30g, Herba Senecionis Scandentis 30g, Fructus Sophorae 20g, Herba Equiseti Hiemalis 20g, Semen Cuscutae 20g, Semen Plantaginis 20g, borneol 20g.

Embodiment 3, a kind of Chinese medicine composition for the treatment of keratoconjunctivitis is to be made by thorn youth fruit 70g, Herba Violae diffusae 50g, Radix Hibisci Rosae-Sinensis 40g, Radix Clematidis 40g, Semen Lepidii (Semen Descurainiae) 40g, Herba Senecionis Scandentis 40g, Fructus Sophorae 30g, Herba Equiseti Hiemalis 30g, Semen Cuscutae 30g, Semen Plantaginis 30g, borneol 30g.

Claims (2)

1. Chinese medicine composition for the treatment of keratoconjunctivitis is characterized in that it is to be made by following raw material medicaments:

Thorn youth fruit 40-70 part, Herba Violae diffusae 30-50 part, Radix Hibisci Rosae-Sinensis 20-40 part, Radix Clematidis 20-40 part, Semen Lepidii (Semen Descurainiae) 20-40 part, Herba Senecionis Scandentis 20-40 part, Fructus Sophorae 10-30 part, Herba Equiseti Hiemalis 10-30 part, Semen Cuscutae 10-30 part, Semen Plantaginis 10-30 part, borneol 10-30 part.

2. Chinese medicine composition according to claim 1 is characterized in that it is to be made by following raw material medicaments:

50 parts of thorn youth fruits, 40 parts of Herba Violae diffusaes, 30 parts of Radix Hibisci Rosae-Sinensiss, 30 parts of Radix Clematidis, 30 parts of Semen Lepidii (Semen Descurainiae)s, 30 parts of Herba Senecionis Scandentiss, 20 parts of the Fructuss Sophorae, 20 parts of Herba Equiseties Hiemalis, 20 parts of Semen Cuscutae, 20 parts of Semen Plantaginiss, 20 parts of borneol.