CN102772740A - Medicine for curing chronic respiratory disease of chicken - Google Patents

Abstract

The invention belongs to the technical field of medicine, and in particular relates to a medicine for curing chronic respiratory disease of chicken. The medicine is prepared by using Chinese medicinal herbs as raw materials, i.e. concha haliotidis, semen cassiae torae, rhizoma atractylodis, balloonflower root, Chinese rhubarb, Baikal skullcap root, dried orange peel, radix sophorae falvescentis, Glycyrrhiza uralensis, Gardenia, Curcuma aromatica, herba houttuyniae and perilla leaf; and powder is prepared by crashing, filtering and mixing according to conventional method. The medicine for curing chronic respiratory disease of chicken has the characteristics of becoming effective quickly and having good curative effect and no obvious side effect.

Description

A kind of medicine of treating the chicken chronic respiratory tract disease

Technical field

The invention belongs to a kind of technical field of pharmaceuticals, being specifically related to a kind of is the treatment chicken chronic respiratory tract disease medicine that raw material is processed with the Chinese herbal medicine.

Background technology

The chicken chronic respiratory tract disease can cause that growth of meat chicken speed significantly reduces, and feedstuff-meat ratio obviously improves; Laying hen reduces with the laying rate of planting chicken, abnormal-shape egg increases, the hatching of breeding eggs rate reduces, strong young rate descends.Respiratory tract disease taking place easily in the growth of meat chicken process, or when immune respiratory tract live-virus vaccine, be very easy to serious vaccine reaction takes place, causes the increase and the production loss of medicine expense.

Because Frustrate blood and mycoplasma and colibacillary mixed infection, cause around serious airsacculitis, the pericarditis regulating liver-QI inflammation etc., cause significantly improving of mortality rate and mortality.According to statistics, after the kind chicken infected Frustrate blood and mycoplasma, feed conversion rate reduced by 10%～20%, and death rate rises 10%～20%; Peak phase laying rate falls 5%～10%; The laying rate of laying hen descends 10%～20%; The weak young bird increase by 10% of hatching of breeding eggs rate reduction by 5%～10%, chickling, the body weight reduction about 38 of broiler, marketing time prolong, treat cost rising (how every broiler is with about 0.3 yuan).

Chronic respiratory disease is a kind of chronic respiratory infectious disease that is caused by mycoplasma gallisepticum.It is characterized in that cough, sneeze and tracheal rale, cheesy thing is arranged in upper respiratory tract infection and the trachea, adult chicken is inapparent infection.Primary disease is distributed in countries in the world, also is one of important infectious disease of harm poultry husbandry.Infect this after being ill, laying rate, incubation rate, rate of fertilization all reduce, weak young rate increases about 10%, and the pathology damage of respiratory system can appear in broiler, can cause body weight to reduce by 38%, and feedstuff-meat ratio, expenses for medicine improve, and cause enormous economic loss.

The chicken chronic respiratory tract disease is with cough, mouth breathing, shed tears, eye is wiped wing, pawl is grabbed eye, stream nose liquid, ataxia, respiratory tract gong sound, hole swelling under visible the facial area swelling, particularly socket of the eye of later stage.Kind of laying rate of chicken descends, the hatching egg qualification rate reduces, incubation rate reduces, death rate raises is one type of disease of principal character; Be one type of the chicken house normal property disease of sending out, become poultry husbandry and veterinary's diagnosis and treatment personnel one of stubborn problem very clinically, respiratory tract disease nearly all takes place in the scale chicken house; Its sickness rate is 30%-60%; Mortality rate is 5%-30%, and difficult anti-difficult control, gives to produce and causes enormous economic loss.In clinical treatment, because antibiotic life-time service causes endurance strain constantly to increase, seriously influenced therapeutic effect, it is more to add secondary infection clinically again, has more increased the treatment difficulty to the chicken respiratory disease, presses conventional therapy clinically and is difficult to.Imitate fowl disease and use herbal control, in China long history is arranged, so far, it still has important practical significance to the control of fowl disease.In recent years, the broad research to Chinese herbal medicine shows that it not only has effect disease-resistant, enhancing immunity, can also improve efficiency of feed utilization and conversion ratio, generation growth promotion effect.

The chicken chronic respiratory tract disease is mainly caused by combineds effect such as Frustrate blood and mycoplasma, escherichia coli, the wherein main effect of Frustrate blood and mycoplasma performance, and promptly factor such as mycoplasma, escherichia coli is under poor environment factor condition; Serious respiratory tract disease syndrome takes place, and mycoplasma mainly is present on trachea, the air bag, under the influence of stressors; Abwehrkraft des Koepers reduces, and mycoplasma can be bred in a large number, and quantity increases; Virulence strengthens, and destroys trachea, bronchus cilium, and the oscillatory forces of cilium is weakened; The ability of repelling foreign body reduces; Other bacillary, viral cause of disease is deposited to alveolar, bronchioles with dust more easily, or direct extension causes morbidity to air bag.Sometimes the startup effect of mycoplasma possibly be exactly escherichia coli or other cause of disease to the murderous main cause of chicken after accomplishing.

It mainly is nasal sinuses, trachea, air bag pathological changes that anatomy and pathology changes.Nasal sinuses has mucus, mucosa congestion; Eye conjunctiva congestion; Tracheal mucosa is congested, mucus is arranged; Lungs one or both sides nearly bronchus end congestion, later stage larynx are only, have canescence or faint yellow cheese thing in the trachea, bronchus.Air bag is muddy, filthy thickening, has yellow cheese thing to adhere to sometimes; The secondary escherichia coli fibrinous pericarditis, perihepatitis and peritonitis, salpingitis, oophoritis etc. occur after being ill.

The Chinese herbal medicine toxic and side effects is little, can not produce drug resistance, the resistance against diseases that stress to regulate allomeric function during application, improves body self, and prolonged application is safe and reliable.

Summary of the invention

The purpose of this invention is to provide a kind of instant effect, good effect, and the medicine of the treatment chicken chronic respiratory tract disease of non-evident effect.

The medicine of chicken chronic respiratory tract disease of the present invention is that the Chinese herbal medicine by following parts by weight is that raw material is processed:

Concha Haliotidis 45 ~ 50, Semen Cassiae 40 ~ 50, Rhizoma Atractylodis 45 ~ 50, Radix Platycodonis 45 ~ 50, Radix Et Rhizoma Rhei 30 ~ 40, Radix Scutellariae 30 ~ 40, Pericarpium Citri Reticulatae 30 ~ 40, Radix Sophorae Flavescentis 30 ~ 40, Radix Glycyrrhizae 30 ~ 40, Fructus Gardeniae 30 ~ 40, Radix Curcumae 30 ~ 40, Herba Houttuyniae 90 ~ 100, Folium Perillae 50 ~ 65.

Can said medicine be processed pill on the pharmaceutics, oral liquid, powder etc., consider that clinical practice is easy to use, be reluctant to search for food after the animal morbidity, practical situation such as product stability, preferred dosage form is a powder.

The method for preparing of drug powder of the present invention is:

Take by weighing the above-mentioned raw materials medicine according to weight portion, according to conventional method, through pulverizes, sieve, mixed must powder.

In the prescription of the present invention: Concha Haliotidis, Semen Cassiae liver heat removing and eyesight improving; The Fructus Gardeniae clearing away heat-fire, removing pathogenic heat from blood and toxic substance from the body; Radix Et Rhizoma Rhei, the detumescence of Radix Curcumae blood activating and trace dispersing; The Herba Houttuyniae heat-clearing and toxic substances removing is controlled lung abscess nose pus; Folium Perillae, Radix Glycyrrhizae are induced sweat and reduce phlegm, relieving cough and asthma; Radix Sophorae Flavescentis, Rhizoma Atractylodis, heat clearing and damp drying, strengthening the spleen to promote digestion; Spleen invigorating during Pericarpium Citri Reticulatae is regulated the flow of vital energy and transferred; The Radix Platycodonis medicine carrying is up, clearing throat.Full side has clearing away heat,cooling blood and removing toxin, relieving cough and asthma, the effect that suppressing the hyperactive liver makes eye bright.

The medicine of chicken chronic respiratory tract disease of the present invention is applicable to the chicken cough due to lung-heat, mouth breathing, and diseases such as respiratory tract rale, inappetence, large-scale application prove that curative effect is fast, good effect.Medicine of the present invention belongs to pure Chinese medicinal preparation, compares no drug residue with Western medicine, has no side effect.

The clinical treatment test report

The cough due to lung-heat appears to 180, mouth breathing, and the white plumage broiler of clinical symptoms such as respiratory tract rale, inappetence has carried out therapeutic test with medicine of the present invention, and matched group is the powder for clearing lung-heat that certain company produces.

Ill chicken is from Changzhi City suburb, Shanxi Province and small towns, totally 180 white plumage broiler.Course of disease weak point person went to a doctor in 1-2 days, and the elder went to a doctor about 5 days.Clinical symptoms shows as that the disease pertussis is coughed, mouth breathing, shed tears, eye is wiped wing, pawl is grabbed eye, stream nose liquid, ataxia, respiratory tract gong sound, hole swelling under visible the facial area swelling, particularly socket of the eye of later stage has mucus, mucosa congestion through the visible nasal sinuses of pathological anatomy; Eye conjunctiva congestion; Tracheal mucosa is congested, mucus is arranged; Lungs one or both sides nearly bronchus end congestion, later stage larynx are only, have canescence or faint yellow cheese thing in the trachea, bronchus.Air bag is muddy, filthy thickening, has yellow cheese thing to adhere to sometimes, finally is diagnosed as chronic respiratory disease.In 180 sick chickens, with sick chicken each half with medicine of the present invention and control drug treatment.Medicine of the present invention is got Concha Haliotidis, Semen Cassiae, Rhizoma Atractylodis, each 50 gram of Radix Platycodonis, Radix Et Rhizoma Rhei, Radix Scutellariae, Pericarpium Citri Reticulatae, Radix Sophorae Flavescentis, each 40 gram of Radix Glycyrrhizae, Fructus Gardeniae, each 35 gram of Radix Curcumae; Herba Houttuyniae 100 grams, Folium Perillae 60 grams are through pulverizing, sieving, mix; Be prepared into powder, powder of the present invention is reduced by half by only grow up dosage, the chick of chicken of 5g/, lung heat clearing powder reduces by half with only grow up dosage, the chick of chicken of 5g/ respectively; Reconstitute with boiled water, wait temperature and irritate clothes.

Result of the test see table 1,

The therapeutic outcome of table 1. medicine of the present invention and control drug

The chicken early-stage cases: sick pertussis is coughed, mouth breathing, shed tears

Chicken case in mid-term: ataxia, respiratory tract gong sound

Chicken later stage case: hole swelling under the facial area swelling, particularly socket of the eye

Result of the test shows that medicine of the present invention is 82.2% to the respiratory tract disease cure rate of chicken, and effective percentage is 95.6%; And the cure rate of contrast is 44.4%; Effective percentage is 62.2%, and through statistical analysis, the cure rate of medicine of the present invention and effective percentage comparison all are utmost point significant difference (P ﹤ 0.01) according to medicine.Medicine of the present invention is described from clinical efficacy, chicken chronic respiratory tract disease therapeutic effect obviously is better than control drug, and have that curative effect is fast, the characteristics of good effect (cure rate is 82.2%, and effective percentage is 95.6%).

The specific embodiment

Embodiment 1

Take by weighing according to weight:

Concha Haliotidis 45g, Semen Cassiae 40g, Rhizoma Atractylodis 45g, Radix Platycodonis 45g, Radix Et Rhizoma Rhei 30g, Radix Scutellariae 30g, Pericarpium Citri Reticulatae 30g, Radix Sophorae Flavescentis 30g, Radix Glycyrrhizae 30g, Fructus Gardeniae 30g, Radix Curcumae 30g, Herba Houttuyniae 90g, Folium Perillae 50g.

According to conventional method, pulverize, sieve, mixed powder.

Embodiment 2

Concha Haliotidis 50g, Semen Cassiae 50g, Rhizoma Atractylodis 50g, Radix Platycodonis 50g, Radix Et Rhizoma Rhei 40g, Radix Scutellariae 40g, Pericarpium Citri Reticulatae 40g, Radix Sophorae Flavescentis 40g, Radix Glycyrrhizae 40g, Fructus Gardeniae 40g, Radix Curcumae 40g, Herba Houttuyniae 100g, Folium Perillae 65g.

According to conventional method, pulverize, sieve, mixed powder.

Embodiment 3

Concha Haliotidis 46g, Semen Cassiae 45g, Rhizoma Atractylodis 46g, Radix Platycodonis 46g, Radix Et Rhizoma Rhei 35g, Radix Scutellariae 35g, Pericarpium Citri Reticulatae 35g, Radix Sophorae Flavescentis 35g, Radix Glycyrrhizae 35g, Fructus Gardeniae 35g, Radix Curcumae 35g, Herba Houttuyniae 95g, Folium Perillae 60g.

According to conventional method, pulverize, sieve, mixed powder.

Claims (1)

1. a medicine of treating the chicken chronic respiratory tract disease is pulverized, is sieved, is mixed and made into powder through conventional method, and it is characterized in that: the crude drug by following parts by weight is processed:

Concha Haliotidis 45 ~ 50, Semen Cassiae 40 ~ 50, Rhizoma Atractylodis 45 ~ 50, Radix Platycodonis 45 ~ 50, Radix Et Rhizoma Rhei 30 ~ 40, Radix Scutellariae 30 ~ 40, Pericarpium Citri Reticulatae 30 ~ 40, Radix Sophorae Flavescentis 30 ~ 40, Radix Glycyrrhizae 30 ~ 40, Fructus Gardeniae 30 ~ 40, Radix Curcumae 30 ~ 40, Herba Houttuyniae 90 ~ 100, Folium Perillae 50 ~ 65.