CN102698040A - Medicament for treating porcine respiratory disease and preparation method of medicament - Google Patents
Medicament for treating porcine respiratory disease and preparation method of medicament Download PDFInfo
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- CN102698040A CN102698040A CN2012102017686A CN201210201768A CN102698040A CN 102698040 A CN102698040 A CN 102698040A CN 2012102017686 A CN2012102017686 A CN 2012102017686A CN 201210201768 A CN201210201768 A CN 201210201768A CN 102698040 A CN102698040 A CN 102698040A
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Abstract
The invention discloses a medicament for treating a porcine respiratory disease and a preparation method of the medicament. The medicament for treating the porcine respiratory disease consists of the following Chinese medicinal herb raw materials: rhubarb, coptis root, baikal skullcap root, amur corktree bark, asiatic moonseed rhizome, dandelion, liquoric root, gypsum, airpotato yam, virgate wormwood herb, purpleflower holly leaf, Chinese thorowax root and Chinese ephedra. The preparation method of the medicament for treating the porcine respiratory disease comprises the following steps of: weighing a certain amount of each Chinese medicinal herb raw material; and smashing, sieving and mixing into powder. The medicament for treating the porcine respiratory disease is suitable for symptoms such as porcine triple warmer and high fire, cough with lung heat, jaundice with damp-heat pathogen, swelling and pain in throat, aphtha of the mouth and tongue and the like. As proved by large-scale application, the curative ratio is over 82 percent, and the effective ratio is over 95 percent. The medicament disclosed by the invention belongs to a pure Chinese medicinal preparation; and compared with a western medicament, the medicament has the advantages of freeness from medicinal residues and toxic and side effects.
Description
Technical field
The present invention relates to treat the pharmaceutical composition of domestic animal respiratory tract disease, particularly relating to a kind of is the medicine of the treatment porcine respiratory disease processed of raw material with the Chinese herbal medicine, the invention still further relates to the method for preparing of this medicine.
Background technology
The porcine respiratory disease is to be one type of disease of principal character with cough, asthma and dyspnea; It is the one type of normal property sent out disease on pig farm; Become pig industry and veterinary's diagnosis and treatment personnel one of stubborn problem very clinically, respiratory tract disease nearly all takes place in large-scale pig farm, and its sickness rate is 30%-60%; Mortality rate is 5%-30%, and difficult anti-difficult control.Respiratory tract disease comprises acute pneumonia and chronic mildness pneumonia, can cause death when acute pneumonia is serious; Chronic mildness pneumonia make the pig rate of growth slowly with the reduction of price of deed rate, it is more serious to cause swinery to fatten the inconsistent problem that makes of rate.Therefore respiratory tract disease is still the principal disease that influences Swine Production, and concerning pig industry, respiratory tract disease is to cause the disease of maximum economic loss.It is reported that all there is mycoplasma pneumonia in the pig farm of U.S. 70%-80%; Pig after inspection is butchered, about 50% lung has the mycoplasma pneumonia pathological changes.In clinical treatment, because the life-time service antibiotic causes endurance strain constantly to increase; Seriously influenced therapeutic effect; It is more to add secondary infection clinically again, has increased the treatment difficulty to porcine respiratory disease, clinically by the western medicine DeGrain of routine.Using herbal control porcine respiratory disease has long history in China, and it still has important practical significance to the control of porcine respiratory disease so far.In recent years, the broad research to Chinese herbal medicine shows that the Chinese herbal medicine toxic and side effects is little; Can not produce drug resistance; Stress to regulate allomeric function during application, improve the resistance against diseases and the enhancing immunity of body self, prolonged application is safe and reliable; Can also improve efficiency of feed utilization and conversion ratio, produce the growth promotion effect.
Summary of the invention
The purpose of this invention is to provide a kind of medicine of treating the porcine respiratory disease, fast with this Drug therapy porcine respiratory curative effect of disease, good effect, and do not have significant side effects, the present invention also extracts the method for preparing of this medicine.
The medicine of treatment porcine respiratory disease of the present invention is to be processed by the raw material of Chinese medicine medicine of following mass parts: Radix Et Rhizoma Rhei 55 ~ 65, Rhizoma Coptidis 15 ~ 20, Radix Scutellariae 40 ~ 45, Cortex Phellodendri 25 ~ 35, Rhizoma Menispermi 25 ~ 35, Herba Taraxaci 70 ~ 80, Radix Glycyrrhizae 55 ~ 65, Gypsum Fibrosum 50 ~ 60, Rhizoma Dioscoreae Bulbiferae 20 ~ 30, Herba Artemisiae Scopariae 20 ~ 30, Ilex purpurea Hassk.[I.chinensis Sims 15 ~ 20, Radix Bupleuri 20 ~ 25, Herba Ephedrae 15 ~ 25.
Further, the raw material of Chinese medicine medicine of the preferred following mass parts of medicine of treatment porcine respiratory disease of the present invention is processed: Radix Et Rhizoma Rhei 60, Rhizoma Coptidis 18, Radix Scutellariae 45, Cortex Phellodendri 30, Rhizoma Menispermi 30, Herba Taraxaci 75, Radix Glycyrrhizae 60, Gypsum Fibrosum 60, Rhizoma Dioscoreae Bulbiferae 24, Herba Artemisiae Scopariae 24, Ilex purpurea Hassk.[I.chinensis Sims 18, Radix Bupleuri 21, Herba Ephedrae 20.
Can said medicine be processed oral liquid on the pharmaceutics, powder etc., consider be reluctant to search for food after the animal morbidity, clinical practice is easy to use and practical situation such as product stability, preferred dosage form is a powder.
The method for preparing of the drug powder of treatment porcine respiratory disease of the present invention is following:
Take by weighing each raw material of Chinese medicine by above-mentioned mass parts, through pulverizing, sieve, be mixed and made into powder.
The method for using that the present invention treats the drug powder of porcine respiratory disease is: dosage, the piglet of powder of the present invention by the adult pig of 20g/ head reduced by half, reconstitute with boiled water, wait temperature and irritate clothes, once a day, taking 7 days continuously is a course of treatment.
The card of all excess-heat fire-toxin three warmers intenseness of heat, big heat is fidgety, mouth is made an uproar pharyngalgia, or intenseness of heat is sent out speckle, the cough due to lung-heat; Be born in stomach aphtha of the mouth and tongue stagnant heat on burning hot and steam to smoke and more then be jaundice outward, though to sum up the discrimination we to control card many, how its cause of disease then is by the endogenous fire excessive noxious heat; Be full of three warmers, so the side uses the Rhizoma Coptidis eliminating heart-fire to be monarch, Jiao's fire in double the rushing down, the fire of the Radix Scutellariae lung heat clearing diarrhea of heat type part of the body cavity above the diaphragm housing the heart and lungs; The fire that Cortex Phellodendri is rushed down the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is a minister, and we are at clinical application, and constipation person adds Radix Et Rhizoma Rhei to rush down excess-heat down, Rhizoma Menispermi, Herba Taraxaci, Gypsum Fibrosum, Rhizoma Dioscoreae Bulbiferae, Folium Ilicis Purpureae; With clear sore-throat relieving at a distance from and subside a swelling, Radix Bupleuri, Herba Ephedrae be with relieving the exterior syndrome by diaphoresis, expelling wind and clearing away heat, Radix Glycyrrhizae is to separate hundred poison with all medicines; All because of in the fire-toxin superinverse, give birth to all cards outward more, through pathogenic fire purging, the agent that expels the heat-evil, the then all disease self-balancing that descends of its fire-toxin.
The medicine of treatment porcine respiratory disease of the present invention is applicable to pig three warmers fire Sheng, cough due to lung-heat, jaundice due to damp-heat, laryngopharynx swelling and pain, aphtha of the mouth and tongue.Etc. disease, large-scale application proves that cure rate is more than 82%, and effective percentage is more than 95%.Medicine of the present invention belongs to pure Chinese medicinal preparation, compares no drug residue with Western medicine, has no side effect.
The clinical treatment test report
The cough due to lung-heat appears to 90, jaundice due to damp-heat, and the pig of clinical symptoms such as laryngopharynx swelling and pain has carried out therapeutic test with medicine of the present invention, and matched group is the Xiaohuang granule that certain company produces.
Ill pig is from Changzhi City suburb, Shanxi Province and small towns, and totally 90, be big yorker, wherein sow 58 examples are bred pig 22 examples, piglet 10 examples.Course of disease weak point person went to a doctor in 1-2 days, and the elder went to a doctor about 5 days.Clinical symptoms shows as disease pig limbs tip and visual mucosa cyanosis, becomes thin, coughs, pants, and there is the stickiness exudate in dyspnea in various degree and nostril, and appetite reduces or is useless exhausted.In 90 sick pigs, be diagnosed as 44 examples that have of pig lung plague, be diagnosed as 26 examples that have of mycoplasma pneumoniae of swine, be diagnosed as 20 examples that have of swine flue, the sick pigs of various diseases each half are treated with medicine of the present invention and control drug.
Medicine of the present invention is got 6 parts of Radix Et Rhizoma Rhei, 1.8 parts of Rhizoma Coptidis, 4.5 parts of Radix Scutellariaes, 3 parts of Cortex Phellodendris, 3 parts of Rhizoma Menispermis, 7.5 parts of Herba Taraxacis, 6 parts in Radix Glycyrrhizae, 6 parts in Gypsum Fibrosum, 2.4 parts of Rhizoma Dioscoreae Bulbiferaes, 2.4 parts of Herba Artemisiae Scopariaes, 1.8 parts of Ilex purpurea Hassk.[I.chinensis Sims, 2.1 parts of Radix Bupleuri, 2 parts in Herba Ephedrae; Through pulverizing, sieving, mix; Be prepared into powder, dosage, the piglet of powder of the present invention by the adult pig of 20g/ head reduced by half, the Xiaohuang granule agent reduces by half with dosage, the piglet of the adult pig of 20 g/ heads respectively; Reconstitute with boiled water; Wait temperature and irritate clothes, once a day, took continuously 7 days.Effective percentage=healing number+significant figure/treatment sum.Result of the test is seen table 1.
The therapeutic outcome of table 1 medicine of the present invention and control drug
Result of the test shows that medicine of the present invention is 82.2% to the respiratory tract disease cure rate of pig, and effective percentage is 95.6%; And the cure rate of contrast is 44.4%; Effective percentage is 62.2%, and through statistical analysis, the cure rate of medicine of the present invention and effective percentage comparison all are utmost point significant difference (P ﹤ 0.01) according to medicine.Medicine of the present invention is described from clinical efficacy, the treatment of respiratory diseases effect of pig obviously is better than control drug, and has fast, the eutherapeutic characteristics of curative effect.
Embodiment 1
Get Radix Et Rhizoma Rhei 6 kg, Rhizoma Coptidis 1.8 kg, Radix Scutellariae 4.5 kg, Cortex Phellodendri 3 kg, Rhizoma Menispermi 3 kg, Herba Taraxaci 7.5 kg, Radix Glycyrrhizae 6 kg, Gypsum Fibrosum 6 kg, Rhizoma Dioscoreae Bulbiferae 2.4 kg, Herba Artemisiae Scopariae 2.4 kg, Ilex purpurea Hassk.[I.chinensis Sims 1.8 kg, Radix Bupleuri 2.1 kg, Herba Ephedrae 2 kg, with said medicine mix to pulverize, sieving is the drug powder of treatment porcine respiratory disease.
Embodiment 2
Get Radix Et Rhizoma Rhei 5.5 kg, Rhizoma Coptidis 1.5 kg, Radix Scutellariae 4 kg, Cortex Phellodendri 2.5 kg, Rhizoma Menispermi 2.5kg, Herba Taraxaci 7kg, Radix Glycyrrhizae 5.5kg, Gypsum Fibrosum 5kg, Rhizoma Dioscoreae Bulbiferae 2kg, Herba Artemisiae Scopariae 2kg, Ilex purpurea Hassk.[I.chinensis Sims 1.5 kg, Radix Bupleuri 2kg, Herba Ephedrae 2 kg, with said medicine mix to pulverize, sieving is the drug powder of treatment porcine respiratory disease.
Embodiment 3
Get Radix Et Rhizoma Rhei 6.5kg, Rhizoma Coptidis 2kg, Radix Scutellariae 4.5kg, Cortex Phellodendri 3.5kg, Rhizoma Menispermi 3.5kg, Herba Taraxaci 8kg, Radix Glycyrrhizae 6.5kg, Gypsum Fibrosum 6kg, Rhizoma Dioscoreae Bulbiferae 3kg, Herba Artemisiae Scopariae 3kg, Ilex purpurea Hassk.[I.chinensis Sims 2kg, Radix Bupleuri 2.5kg, Herba Ephedrae 2.5kg, with said medicine mix to pulverize, sieving is the drug powder of treatment porcine respiratory disease.
Embodiment 4
Get Radix Et Rhizoma Rhei 6.2kg, Rhizoma Coptidis 1.7kg, Radix Scutellariae 4.1kg, Cortex Phellodendri 2.8kg, Rhizoma Menispermi 3.3kg, Herba Taraxaci 7.3kg, Radix Glycyrrhizae 6.2kg, Gypsum Fibrosum 6.1kg, Rhizoma Dioscoreae Bulbiferae 2.4kg, Herba Artemisiae Scopariae 2.5kg, Ilex purpurea Hassk.[I.chinensis Sims 1.6kg, Radix Bupleuri 2.2kg, Herba Ephedrae 2kg, with said medicine mix to pulverize, sieving is the drug powder of treatment porcine respiratory disease.
Claims (3)
1. the medicine of treatment porcine respiratory disease is characterized in that being processed by the raw material of Chinese medicine medicine of following mass parts: Radix Et Rhizoma Rhei 55 ~ 65, Rhizoma Coptidis 15 ~ 20, Radix Scutellariae 40 ~ 45, Cortex Phellodendri 25 ~ 35, Rhizoma Menispermi 25 ~ 35, Herba Taraxaci 70 ~ 80, Radix Glycyrrhizae 55 ~ 65, Gypsum Fibrosum 50 ~ 60, Rhizoma Dioscoreae Bulbiferae 20 ~ 30, Herba Artemisiae Scopariae 20 ~ 30, Ilex purpurea Hassk.[I.chinensis Sims 15 ~ 20, Radix Bupleuri 20 ~ 25, Herba Ephedrae 15 ~ 25.
2. the medicine of treatment porcine respiratory disease according to claim 1 is characterized in that being processed by the raw material of Chinese medicine medicine of following mass parts: Radix Et Rhizoma Rhei 60, Rhizoma Coptidis 18, Radix Scutellariae 45, Cortex Phellodendri 30, Rhizoma Menispermi 30, Herba Taraxaci 75, Radix Glycyrrhizae 60, Gypsum Fibrosum 60, Rhizoma Dioscoreae Bulbiferae 24, Herba Artemisiae Scopariae 24, Ilex purpurea Hassk.[I.chinensis Sims 18, Radix Bupleuri 21, Herba Ephedrae 20.
3. the method for preparing of the medicine of claim 1 treatment porcine respiratory disease, it is characterized in that the raw material of Chinese medicine medicated powder of said mass parts is broken, sieve, be mixed and made into powder.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142859A (en) * | 2013-04-02 | 2013-06-12 | 河北工程大学 | Medicine for controlling swine plague |
| CN106177755A (en) * | 2016-07-15 | 2016-12-07 | 朱广双 | A kind of processing technology of the Chinese medicine formula treating porcine respiratory disease |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101810717A (en) * | 2009-11-09 | 2010-08-25 | 天津瑞贝特科技发展有限公司 | Livestock traditional Chinese medicine composition with function of clearing heat and detoxicating, preparation method and application |
-
2012
- 2012-06-19 CN CN2012102017686A patent/CN102698040A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810717A (en) * | 2009-11-09 | 2010-08-25 | 天津瑞贝特科技发展有限公司 | Livestock traditional Chinese medicine composition with function of clearing heat and detoxicating, preparation method and application |
Non-Patent Citations (3)
| Title |
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| 朱连勤等: "中药防治鸡传染性呼吸道疾病的研究现况与展望", 《中兽医学杂志》 * |
| 杨河清: "四季青片治疗鸡传染性支气管炎病例观察", 《今日种业》 * |
| 杨辉等: "含黄药子制剂的临床应用及不良反应综述", 《临床误诊误治》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103142859A (en) * | 2013-04-02 | 2013-06-12 | 河北工程大学 | Medicine for controlling swine plague |
| CN103142859B (en) * | 2013-04-02 | 2014-09-03 | 河北工程大学 | Medicine for controlling swine plague |
| CN106177755A (en) * | 2016-07-15 | 2016-12-07 | 朱广双 | A kind of processing technology of the Chinese medicine formula treating porcine respiratory disease |
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Application publication date: 20121003 |