CN102742725A - Forage for alleviating chromium poisoning of animals - Google Patents
Forage for alleviating chromium poisoning of animals Download PDFInfo
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- CN102742725A CN102742725A CN2012102273038A CN201210227303A CN102742725A CN 102742725 A CN102742725 A CN 102742725A CN 2012102273038 A CN2012102273038 A CN 2012102273038A CN 201210227303 A CN201210227303 A CN 201210227303A CN 102742725 A CN102742725 A CN 102742725A
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Abstract
The invention relates to a forage for alleviating chromium poisoning of animals. The forage comprises, by weight, 10 to 30 of Indian bread, 15 to 45 of oyster shells, 4 to 8 of liquorice root, 3 to 10 of pseudostellaria root, 25 to 40 of licorice and 55 to 100 of seaweed.
Description
Technical field
The present invention relates to a kind of animal feed, particularly a kind ofly form, be used for a kind of feed of alleviating the animal chromium poisoning by compound plant medicine.
Background technology
Added the analyte of leather and fur products at present a lot of animal feeds; Owing to contain the chromium of high concentration in these analytes; Therefore, caused the incident of animal chromium poisoning often to take place, the animal of chromium poisoning is healthy through food chain approach harm humans; Therefore, the feed of exploitation alleviation animal chromium poisoning has realistic meaning very much.
Summary of the invention
The present invention is a kind of feed of alleviating the animal chromium poisoning.
Composition weight portion of the present invention is: Poria cocos 10～30, oyster 15～45, Radix Glycyrrhizae 4～8, radix pseudostellariae 3～10, Radix Glycyrrhizae 25～40, marine alga 55～100.
Each medicinal material put into be heated to 90-100 ℃ after water soaks into fully and extract 1-3 time, each 1-3 hour, the merging soup; The solution to be concentrated cold to room temperature, centrifugal (1000-2000 changes/min) 30-45min, remove deposition; Slowly add 50-75% ethanol in the concentrate; Leave standstill, concentrate, recovered alcohol does not get final product to there being the alcohol flavor.
The results showed that the present invention has and arranges the chromium effect preferably.
The specific embodiment 1
Composition weight portion of the present invention (gram) is: Poria cocos 10, oyster 15, Radix Glycyrrhizae 4, radix pseudostellariae 3, Radix Glycyrrhizae 25, marine alga 55.
Each medicinal material put into be heated to 90 ℃ after water soaks into fully and extract 2 times, each 2 hours, merge soup, the solution to be concentrated cold is to room temperature; Centrifugal 1500 commentaries on classics/min, 35min removes deposition, slowly adds 55% ethanol in the concentrate; Leave standstill, concentrate, recovered alcohol does not get final product to there being the alcohol flavor.
The specific embodiment 2
Composition weight portion of the present invention (gram) is: Poria cocos 30, oyster 45, Radix Glycyrrhizae 8, radix pseudostellariae 10, Radix Glycyrrhizae 40, marine alga 100.
Each medicinal material put into be heated to 100 ℃ after water soaks into fully and extract 1 time, each 1 hour, merge soup, the solution to be concentrated cold is to room temperature; Centrifugal 2000 commentaries on classics/min, 45min removes deposition, slowly adds 70% ethanol in the concentrate; Leave standstill, concentrate, recovered alcohol does not get final product to there being the alcohol flavor.
The specific embodiment 3
Get 40 of healthy rats, male and female half and half, physique amount are 200～220g, are divided into control group, chromium contamination group, positive control protection group, the specific embodiment 2 protection groups at random, 10 every group, and each 5 of male and female.Respectively to go physiological saline, potassium bichromate (4mg/mg), potassium bichromate (4mg/mg) and copper sulphate (4mg/mg), potassium bichromate (4mg/mg) and the specific embodiment 2 (0.5g/mg) to irritate stomach 30 days.Each is organized rat and all normally feeds.
After experiment finishes, collect blood, detect AST, ALT and LDH, take out liver, observe morphological changes of various tissue components, measure chromium content.
After 30 days; Tangible subacute chromium poisoning has appearred in chromium contamination group rat; Show as movable reduce, body weight gain receives to press down, the liver weight in wet base is obviously unusual, the visible significantly liver cell cloudy swelling of histopathologic examination, parts of fine karyon concentrate and dissolving and focal necrosis focus.The specific embodiment 2 protection groups have reduced chromium the accumulating of liver, and each damages index all has reduction in various degree than chromium contamination group treated animal.
| Dosage | Rat | ?ALT | ?AST | PLD | LDH | Chromium | Body weight | |
| Group | (mg/kg) | Number | ?(Karmen ?unit) | ?(Karmen ?unit) | (U/L) | (U/L) | μg/mg | g |
| Control group | Physiological saline | 10 | ?72±2 | ?105±31 | 235±59 | 2789±178 | 0.093±0.009 | 227±13 |
| Chromium contamination group | Potassium bichromate 4 | ?10 | ?637±112 4 | ?489±95 | 689±156 | 3532±236 | 0.479±0.023 | 168±24 |
| Positive control protection group | Potassium bichromate 4 and copper sulphate 4 | ?10 | ?419±43 | ?372±31 | 474±31 | 3121±245 | 0.256±0.037 | 179±31 |
| The specific embodiment 2 protection groups | The potassium bichromate 4 and the specific embodiment 2 (0.5) | ?10 | ?321±38 | ?224±21 | 351±73 | 2372±312 | 0.112±0.021 | 203±15 |
The specific embodiment 4
Get because of 6 of the pigs of dietary chromium contamination feed, chromium content overproof in the blood adopts the product of the embodiment of the invention 2, every days 50 g/mg, after 6 days, chromium contamination symptom all disappears, after 15 days in the blood chromium content recover.
Claims (2)
1. the present invention is a kind of feed of alleviating the animal chromium poisoning: composition weight portion of the present invention is: Poria cocos 10～30, oyster 15～45, Radix Glycyrrhizae 4～8, radix pseudostellariae 3～10, Radix Glycyrrhizae 25～40, marine alga 55～100.
2. the present invention is a kind of preparation method of alleviating the feed of animal chromium poisoning:
Each medicinal material put into be heated to 90-100 ℃ after water soaks into fully and extract 1-3 time, each 1-3 hour, the merging soup; The solution to be concentrated cold to room temperature, centrifugal (1000-2000 changes/min) 30-45min, remove deposition; Slowly add 50-75% ethanol in the concentrate; Leave standstill, concentrate, recovered alcohol does not get final product to there being the alcohol flavor.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN2012102273038A CN102742725B (en) | 2012-07-03 | 2012-07-03 | Forage for alleviating chromium poisoning of animals |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102273038A CN102742725B (en) | 2012-07-03 | 2012-07-03 | Forage for alleviating chromium poisoning of animals |
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| Publication Number | Publication Date |
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| CN102742725A true CN102742725A (en) | 2012-10-24 |
| CN102742725B CN102742725B (en) | 2013-10-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN2012102273038A Expired - Fee Related CN102742725B (en) | 2012-07-03 | 2012-07-03 | Forage for alleviating chromium poisoning of animals |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103330096A (en) * | 2013-07-17 | 2013-10-02 | 北京众开颜科技有限公司 | Traditional Chinese medicine feed supplement and application thereof |
| CN105902563A (en) * | 2016-06-24 | 2016-08-31 | 山东农业大学 | Hexavalent-chromium toxicity removal agent for chickens |
| CN113171389A (en) * | 2021-05-27 | 2021-07-27 | 尼腾(广州)生物科技有限公司 | Pharmaceutical composition with detoxification function and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1465285A (en) * | 2002-06-28 | 2004-01-07 | 中国科学院大连化学物理研究所 | Lead-removing health care food and preparation method thereof |
| CN101904917A (en) * | 2010-02-05 | 2010-12-08 | 封士兰 | Medicinal composition for removing lead and preparation method thereof |
| CN102091269A (en) * | 2011-03-05 | 2011-06-15 | 中国农业科学院兰州畜牧与兽药研究所 | Medicament for treating lead poisoning of ruminant |
-
2012
- 2012-07-03 CN CN2012102273038A patent/CN102742725B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1465285A (en) * | 2002-06-28 | 2004-01-07 | 中国科学院大连化学物理研究所 | Lead-removing health care food and preparation method thereof |
| CN101904917A (en) * | 2010-02-05 | 2010-12-08 | 封士兰 | Medicinal composition for removing lead and preparation method thereof |
| CN102091269A (en) * | 2011-03-05 | 2011-06-15 | 中国农业科学院兰州畜牧与兽药研究所 | Medicament for treating lead poisoning of ruminant |
Non-Patent Citations (2)
| Title |
|---|
| 《中国中医基础医学杂志》 20120331 王旭等 海藻配伍甘草古代方药运用与评述 第18卷, 第3期 * |
| 王旭等: "海藻配伍甘草古代方药运用与评述", 《中国中医基础医学杂志》, vol. 18, no. 3, 31 March 2012 (2012-03-31) * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103330096A (en) * | 2013-07-17 | 2013-10-02 | 北京众开颜科技有限公司 | Traditional Chinese medicine feed supplement and application thereof |
| CN103330096B (en) * | 2013-07-17 | 2014-11-26 | 北京众开颜科技有限公司 | Traditional Chinese medicine feed supplement and application thereof |
| CN105902563A (en) * | 2016-06-24 | 2016-08-31 | 山东农业大学 | Hexavalent-chromium toxicity removal agent for chickens |
| CN113171389A (en) * | 2021-05-27 | 2021-07-27 | 尼腾(广州)生物科技有限公司 | Pharmaceutical composition with detoxification function and application thereof |
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| Publication number | Publication date |
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| CN102742725B (en) | 2013-10-23 |
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Owner name: NINGBO YINZHOU FURUIDA BIOTECHNOLOGY CO., LTD. Free format text: FORMER OWNER: NINGBO YINZHOU HAOSI RUIPU BIOTECHNOLOGY CO., LTD. Effective date: 20131017 |
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Effective date of registration: 20131017 Address after: 315199 Zhejiang city of Ningbo province Yinzhou District Zhonggongmiao Street Tiantong Road No. 1388 room 3624 Patentee after: Ningbo Yinzhou Furuida Biotechnology Co., Ltd. Address before: 315100 Zhejiang city of Ningbo province Yinzhou District River Street 4 No. 11 Kaixuan tomorrow Patentee before: Ningbo Yinzhou Haosi Ruipu Biological Technology Co., Ltd. |
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