CN102658887A - Discharging device based on RABS (Restricted Access Barrier System) - Google Patents

Discharging device based on RABS (Restricted Access Barrier System) Download PDF

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Publication number
CN102658887A
CN102658887A CN2012101475174A CN201210147517A CN102658887A CN 102658887 A CN102658887 A CN 102658887A CN 2012101475174 A CN2012101475174 A CN 2012101475174A CN 201210147517 A CN201210147517 A CN 201210147517A CN 102658887 A CN102658887 A CN 102658887A
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CN
China
Prior art keywords
insulated chamber
upper strata
rabs
shielded box
lower floor
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012101475174A
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Chinese (zh)
Inventor
刘乾峰
贺建军
康峰
熊怒怀
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Truking Technology Ltd
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Truking Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Truking Technology Ltd filed Critical Truking Technology Ltd
Priority to CN2012101475174A priority Critical patent/CN102658887A/en
Publication of CN102658887A publication Critical patent/CN102658887A/en
Pending legal-status Critical Current

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Abstract

The invention discloses a discharging device based on an RABS (Restricted Access Barrier System). The discharging device comprises a discharging nozzle. The RABS is mounted at an outlet end of the discharging nozzle. The discharging device based on the RABS has a simple structure, can effectively prevent discharged materials from being polluted, and entirely meets requirements of a GMP (Good Manufacturing Practice).

Description

Drawing mechanism based on the RABS system
Technical field
The present invention relates to medicine, food packing machine technical field, relate in particular to drawing mechanism based on the RABS system.
Background technology
Drawing mechanism in the existing medical packaging machinery, the working environment of its discharging ozzle is the requirement of out of reach GMP (GMP) often, influences the safety of medicine.For example; Rubber plug cleaning machine is when work; Its whole equipment all places and has in the A level zone that the B level zone of laminar winds is perhaps opened from top to bottom, and it is regional that its discharging ozzle also is in the perhaps open A level in B level zone, contaminated easily when the plug discharging after the cleaning; Drug safety property can not get reliable guarantee, does not meet the requirement of GMP.
Summary of the invention
The technical matters that the present invention will solve is the deficiency that overcomes prior art, provides that a kind of material simple in structure, that can effectively avoid exporting is contaminated, the drawing mechanism based on the RABS system of complete GMP compatible.
For solving the problems of the technologies described above, the present invention adopts following technical scheme:
A kind of drawing mechanism based on the RABS system comprises the discharging ozzle, and the exit end of said discharging ozzle is equiped with the RABS system.
Said RABS system comprises shielded box and is used to said shielded box the hundred grade laminar flow hood of horizontal flow to laminar winds are provided that said hundred grades of laminar flow hood vertically are arranged in a side of said shielded box.
Said shielded box comprises upper strata insulated chamber and lower floor's insulated chamber, is provided with the isolating door that can be communicated with or separate the two between said upper strata insulated chamber and the lower floor insulated chamber, and the outlet of said upper strata insulated chamber and said discharging ozzle is joined.
Said shielded box is provided with at least one open and close door that is used to connect discharging ozzle and upper strata insulated chamber.
Be provided with Weighing mechanism and the supporting mechanism that extends to the upper strata insulated chamber in the said lower floor insulated chamber, be provided with the clamping bag openning body and the heat sealing mechanism that are installed on the said supporting mechanism in the insulated chamber of said upper strata.
Said upper strata insulated chamber and lower floor's insulated chamber are equipped with independently glass door, and the glass door that is positioned at insulated chamber zone, said upper strata is provided with the sterile working gloves.
Be equipped with the hook that is used to hang packaging bag in said upper strata insulated chamber and the lower floor's insulated chamber.
Offer on the sidewall relative on the said shielded box and let out the wind hole with said hundred grades of laminar flow hood.
Compared with prior art, the invention has the advantages that:
Drawing mechanism based on the RABS system of the present invention; Exit end at the discharging ozzle is equiped with the RABS system; RABS (Restricted Access Barrier System) is the bacterium manufacturing process isolated system that meets grade standard in the world; Receive the protection of A level laminar region when making the discharging of discharging ozzle in this system of the exit end of discharging ozzle installing, the material that actv. is avoided exporting is contaminated, fully GMP compatible.In the prior art; The influence that blocked by the discharge system of discharging ozzle top; The whole process that vertical laminar winds can not effectively protect material to accomplish to packing from discharging; The present invention adopts hundred grades of laminar flow hood to provide horizontal laminar flow wind to substitute vertical laminar flow wind of the prior art, has got around blocking of discharge system fully, and the whole process that material is accomplished to packing from discharging all receives effective protection of A level laminar region.Shielded box is divided into two-layer up and down, is provided with the isolating door that can be communicated with or separate the two between upper strata insulated chamber and the lower floor insulated chamber, normally during discharging; Isolating door is opened; When need taking out packaged material, isolating door is closed, the upper strata insulated chamber keeps shut; Open lower floor's insulated chamber and therefrom take out packaged material, the A level laminar flow zone to the upper strata insulated chamber in the time of can avoiding like this getting material pollutes.
Description of drawings
Fig. 1 is a main TV structure scheme drawing of the present invention.
Fig. 2 is a plan structure scheme drawing of the present invention.
Fig. 3 is the semi-sictional view structural representation of RABS system.
Fig. 4 is that the A of Fig. 3 is to structural representation.
Fig. 5 is the structural representation after the present invention opens glass door.
Fig. 6 is the perspective view after the present invention removes discharge system.
Fig. 7 is that Fig. 1 removes B behind the connecting mechanism for rotating to view.
Each label is represented among the figure:
1, RABS system; 2, discharging ozzle; 3, packaging bag; 4, washing system; 5, the bucket that connects material; 11, hundred grades of laminar flow hood; 12, shielded box; 13, connecting mechanism for rotating; 120, clamp bag openning body; 121, upper strata insulated chamber; 122, lower floor's insulated chamber; 123, isolating door; 124, glass door; 125, sterile working gloves; 126, hook; 127, open and close door; 128, Weighing mechanism; 129, supporting mechanism; 130, heat sealing mechanism; 131, let out the wind hole; 1231, operating handle.
The specific embodiment
Fig. 1 to Fig. 7 shows a kind of drawing mechanism embodiment based on the RABS system of the present invention; This drawing mechanism comprises discharging ozzle 2; The exit end of discharging ozzle 2 is equiped with RABS system 1; RABS (Restricted Access Barrier System) is the bacterium manufacturing process isolated system that meets grade standard in the world; Receive the protection of A level laminar region when making 2 dischargings of discharging ozzle in this system of the exit end of discharging ozzle 2 installing, the material that actv. is avoided exporting is contaminated, fully GMP compatible.
In the present embodiment; RABS system 1 comprises shielded box 12 and hundred grades of laminar flow hood 11; Hundred grades of laminar flow hood 11 vertically are arranged in a side of shielded box 12, and are used to shielded box 12 and provide horizontal flow to laminar winds, offer on the sidewall relative with hundred grades of laminar flow hood 11 on the shielded box 12 and let out wind hole 131.In the prior art; The influence that blocked by the discharge system of discharging ozzle 2 tops; The whole process that vertical laminar winds can not effectively protect material to accomplish to packing from discharging; Present embodiment adopts horizontal laminar flow wind to substitute vertical laminar flow wind of the prior art, has got around blocking of discharge system fully, and the whole process that material is accomplished to packing from discharging all receives effective protection of A level laminar region.
In the present embodiment, shielded box 12 comprises upper strata insulated chamber 121 and lower floor's insulated chamber 122, and upper strata insulated chamber 121 joins with the outlet of discharging ozzle 2; Be provided with the isolating door 123 that can be communicated with or separate the two between upper strata insulated chamber 121 and the lower floor insulated chamber 122, isolating door 123 is provided with the operating handle 1231 that may command isolating door 123 slides and opens and closes, during normal discharging; Isolating door 123 is opened; When need taking out packaged material, isolating door 123 is closed, upper strata insulated chamber 121 keeps shut; Open lower floor's insulated chamber 122 and therefrom take out packaged material, the A level laminar flow zone to upper strata insulated chamber 121 in the time of can avoiding like this getting material pollutes.
The present invention also can further be provided with at least one open and close door 127 that is used to connect discharging ozzle 2 and upper strata insulated chamber 121 on shielded box 12; Present embodiment is provided with two open and close doors 127; An open and close door 127 is positioned at upper strata insulated chamber 121 tops; Another open and close door 127 is positioned at a side of upper strata insulated chamber 121, and two open and close doors 127 are vertical each other, can be used for different directions on discharging ozzle 2 be connected.
In the present embodiment; Be provided with Weighing mechanism 128 and the supporting mechanism 129 that extends to upper strata insulated chamber 121 in lower floor's insulated chamber 122; Be provided with the clamping bag openning body 120 and heat sealing mechanism 130 that are installed on the supporting mechanism 129 in the upper strata insulated chamber 121; Clamp bag openning body 120 and be positioned at the top that clamps bag openning body 120, upper strata insulated chamber 121 is equipped with independently glass door 124 with lower floor's insulated chamber 122, and the glass door 124 that is positioned at upper strata insulated chamber 121 zones is provided with sterile working gloves 125; Can hang operations such as bag, keying isolating door 123 through sterile working gloves 125; Be equipped with the hook 126 that is used to hang packaging bag 3 in upper strata insulated chamber 121 and the lower floor's insulated chamber 122, also can establish the bucket 5 that connects material that is used for splendid attire packaging bag 3 usefulness, be equiped with connecting mechanism for rotating 13 in a side of shielded box 12 at Weighing mechanism 128 and 123 of isolating doors; This connecting mechanism for rotating 13 is connected with a washing system 4, and shielded box 12 connecting mechanism for rotating 13 is relatively made the rotation adjusting of certain angle.
Principle of work: before the discharging; At first open hundred grades of laminar flow hood 11; Open the open and close door 127 on the shielded box 12 then; Rotate to whole RABS system 1 below of discharge system then, at this moment discharging ozzle 2 just in time is inserted in the upper strata insulated chamber 121, and seals up the connecting bridge of open and close door 127 and upper strata insulated chamber 121.Then open the glass door 124 of lower floor's insulated chamber 122, on the hook 126 that is suspended to stacked package pack 3 in this zone, close the glass door 124 of unlatching then, realize self-cleaning.Then, draw back isolating door 123 backs through sterile working gloves 125 and be hanging to packaging bag 3 on the hook 126 in the top area, accomplish the preceding preparation of discharging, can avoid polluting the A level work environment of upper strata insulated chamber 121.
During discharging; At first the hook 126 of insulated chamber 121 is got next packaging bag 3 from the upper strata; Be clamped to the open end of this packaging bag 3 on the clamping bag openning body 120; Rely on bag function of opening of this mechanism to strut packaging bag 3 then, after packaging bag 3 clamps and struts its bottom is dropped on the Weighing mechanism 128 of below.At this moment, the 2 beginning dischargings of discharging ozzle, after the weight of material on the Weighing mechanism 128 reached systemic presupposition, system's control discharging ozzle 2 stopped the plug that falls, and clamps bag openning body 120 simultaneously and draws close each other, and at this moment heat sealing mechanism 130 is packaging bag 3 heat sealings.After sealing completion, clamp the packaging bag 3 that bag openning body 120 unclamps clamping, packaging bag 3 drops into lower region, close isolating door 123 after, open the glass door 124 of lower floor, the packaging bag 3 of taking out packing materials gets final product.
Drawing mechanism based on the RABS system of the present invention is applied widely, can be widely used in medicine, food packing machines such as rubber plug cleaning machine, bottle cap cleaning machine.
Above-mentioned is preferred embodiment of the present invention, is not the present invention is done any pro forma restriction.Though the present invention discloses as above with preferred embodiment, yet be not in order to limit the present invention.Any those of ordinary skill in the art, under the situation that does not break away from technical scheme scope of the present invention, all the technology contents of above-mentioned announcement capable of using is made many possible changes and modification to technical scheme of the present invention, or is revised as the equivalent embodiment of equivalent variations.Therefore, every content that does not break away from technical scheme of the present invention, all should drop in the scope of technical scheme protection of the present invention any simple modification, equivalent variations and modification that above embodiment did according to technical spirit of the present invention.

Claims (10)

1. the drawing mechanism based on the RABS system comprises discharging ozzle (2), it is characterized in that: the exit end of said discharging ozzle (2) is equiped with RABS system (1).
2. the drawing mechanism based on the RABS system according to claim 1; It is characterized in that: said RABS system (1) comprises shielded box (12) and is used to said shielded box (12) provides the hundred grade laminar flow hood (11) of horizontal flow to laminar winds, and said hundred grades of laminar flow hood (11) vertically are arranged in a side of said shielded box (12).
3. the drawing mechanism based on the RABS system according to claim 2; It is characterized in that: said shielded box (12) comprises upper strata insulated chamber (121) and lower floor's insulated chamber (122); Be provided with the isolating door (123) that can be communicated with or separate the two between said upper strata insulated chamber (121) and the lower floor's insulated chamber (122), said upper strata insulated chamber (121) joins with the outlet of said discharging ozzle (2).
4. the drawing mechanism based on the RABS system according to claim 3 is characterized in that: said shielded box (12) is provided with at least one open and close door (127) that is used to connect discharging ozzle (2) and upper strata insulated chamber (121).
5. the drawing mechanism based on the RABS system according to claim 4; It is characterized in that: be provided with Weighing mechanism (128) in the said lower floor insulated chamber (122) and extend to the supporting mechanism (129) of upper strata insulated chamber (121), be provided with the clamping bag openning body (120) and the heat sealing mechanism (130) that are installed on the said supporting mechanism (129) in the said upper strata insulated chamber (121).
6. according to claim 3 or 4 or 5 described drawing mechanisms based on the RABS system; It is characterized in that: said upper strata insulated chamber (121) and lower floor's insulated chamber (122) are equipped with independently glass door (124), and the glass door (124) that is positioned at said upper strata insulated chamber (121) zone is provided with sterile working gloves (125).
7. according to claim 3 or 4 described drawing mechanisms, it is characterized in that: be equipped with the hook (126) that is used to hang packaging bag (3) in said upper strata insulated chamber (121) and the lower floor's insulated chamber (122) based on the RABS system.
8. the drawing mechanism based on the RABS system according to claim 6 is characterized in that: be equipped with the hook (126) that is used to hang packaging bag (3) in said upper strata insulated chamber (121) and the lower floor's insulated chamber (122).
9. according to claim 2 or 3 or 4 or 5 described drawing mechanisms based on the RABS system, it is characterized in that: said shielded box (12) is gone up to offer on the sidewall relative with said hundred grades of laminar flow hood (11) and is let out wind hole (131).
10. the drawing mechanism based on the RABS system according to claim 8 is characterized in that: said shielded box (12) is gone up to offer on the sidewall relative with said hundred grades of laminar flow hood (11) and is let out wind hole (131).
CN2012101475174A 2012-05-14 2012-05-14 Discharging device based on RABS (Restricted Access Barrier System) Pending CN102658887A (en)

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CN2012101475174A CN102658887A (en) 2012-05-14 2012-05-14 Discharging device based on RABS (Restricted Access Barrier System)

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Application Number Priority Date Filing Date Title
CN2012101475174A CN102658887A (en) 2012-05-14 2012-05-14 Discharging device based on RABS (Restricted Access Barrier System)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105167998A (en) * 2015-08-20 2015-12-23 宜诺(天津)医药工程有限公司 Method for implementing whole process of extraction, concentration and extract collection of traditional Chinese medicines in unclean area

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137254A (en) * 1993-10-29 1996-12-04 袋装冰制造股份有限公司 Automatic ice bagger with self-contained sanitizing system
CN1322285A (en) * 1999-10-02 2001-11-14 罗伯特·博施有限公司 Method and device for introduction of air into processing chamber
WO2004071878A2 (en) * 2003-01-28 2004-08-26 Medical Instill Technologies, Inc. Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial
CN201309819Y (en) * 2008-12-11 2009-09-16 上海东富龙科技股份有限公司 Device for aseptically transporting rubber plug
CN102358512A (en) * 2011-10-28 2012-02-22 楚天科技股份有限公司 Automatic feeding device for capping machine
CN202529178U (en) * 2012-05-14 2012-11-14 楚天科技股份有限公司 Discharging device based on RABS (restricted access barrier system)

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1137254A (en) * 1993-10-29 1996-12-04 袋装冰制造股份有限公司 Automatic ice bagger with self-contained sanitizing system
CN1322285A (en) * 1999-10-02 2001-11-14 罗伯特·博施有限公司 Method and device for introduction of air into processing chamber
WO2004071878A2 (en) * 2003-01-28 2004-08-26 Medical Instill Technologies, Inc. Medicament vial having a heat-sealable cap, and apparatus and method for filling the vial
CN201309819Y (en) * 2008-12-11 2009-09-16 上海东富龙科技股份有限公司 Device for aseptically transporting rubber plug
CN102358512A (en) * 2011-10-28 2012-02-22 楚天科技股份有限公司 Automatic feeding device for capping machine
CN202529178U (en) * 2012-05-14 2012-11-14 楚天科技股份有限公司 Discharging device based on RABS (restricted access barrier system)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105167998A (en) * 2015-08-20 2015-12-23 宜诺(天津)医药工程有限公司 Method for implementing whole process of extraction, concentration and extract collection of traditional Chinese medicines in unclean area
CN105167998B (en) * 2015-08-20 2019-03-05 宜诺(天津)医药工程有限公司 The method that cream overall process is received in traditional Chinese medicine extraction concentration is realized in non-clean area

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Application publication date: 20120912