CN102532140B - 一种美罗培南三水合物的制备方法 - Google Patents
一种美罗培南三水合物的制备方法 Download PDFInfo
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- CN102532140B CN102532140B CN201010614524.1A CN201010614524A CN102532140B CN 102532140 B CN102532140 B CN 102532140B CN 201010614524 A CN201010614524 A CN 201010614524A CN 102532140 B CN102532140 B CN 102532140B
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- meropenem trihydrate
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- 0 C*C*NCC(CC*I)SC(C)(C(*)C1C2*(C)O)S(*)N1C2=O Chemical compound C*C*NCC(CC*I)SC(C)(C(*)C1C2*(C)O)S(*)N1C2=O 0.000 description 1
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- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
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CN201010614524.1A CN102532140B (zh) | 2010-12-21 | 2010-12-21 | 一种美罗培南三水合物的制备方法 |
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CN201010614524.1A CN102532140B (zh) | 2010-12-21 | 2010-12-21 | 一种美罗培南三水合物的制备方法 |
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CN102532140A CN102532140A (zh) | 2012-07-04 |
CN102532140B true CN102532140B (zh) | 2015-03-11 |
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Families Citing this family (2)
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CN103044429B (zh) * | 2013-01-28 | 2015-04-01 | 苏州二叶制药有限公司 | 一种美罗培南的制备方法 |
CN108191869A (zh) * | 2018-01-22 | 2018-06-22 | 重庆天地药业有限责任公司 | 美罗培南的纯化方法 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4888344A (en) * | 1986-07-30 | 1989-12-19 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compound in crystalline form, and its production and use |
WO2006035300A2 (en) * | 2004-09-30 | 2006-04-06 | Ranbaxy Laboratories Limited | A process for the preparation of meropenem |
CN1948312A (zh) * | 2006-03-14 | 2007-04-18 | 深圳市海滨制药有限公司 | 美罗培南的制备方法 |
CN101348486A (zh) * | 2008-08-29 | 2009-01-21 | 深圳市海滨制药有限公司 | 一种美罗培南的制备方法 |
US20090299057A1 (en) * | 2008-07-15 | 2009-12-03 | Khemka Ashwin A | Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem |
WO2010104336A2 (ko) * | 2009-03-13 | 2010-09-16 | 주식회사 대웅제약 | 아연 분말을 이용한 메로페넴의 개선된 제조방법 |
CN101914098A (zh) * | 2010-07-20 | 2010-12-15 | 深圳市海滨制药有限公司 | 美罗培南三水合物结晶的制备方法 |
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2010
- 2010-12-21 CN CN201010614524.1A patent/CN102532140B/zh active Active
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4888344A (en) * | 1986-07-30 | 1989-12-19 | Sumitomo Pharmaceuticals Company, Limited | Carbapenem compound in crystalline form, and its production and use |
WO2006035300A2 (en) * | 2004-09-30 | 2006-04-06 | Ranbaxy Laboratories Limited | A process for the preparation of meropenem |
CN1948312A (zh) * | 2006-03-14 | 2007-04-18 | 深圳市海滨制药有限公司 | 美罗培南的制备方法 |
US20090299057A1 (en) * | 2008-07-15 | 2009-12-03 | Khemka Ashwin A | Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem |
CN101348486A (zh) * | 2008-08-29 | 2009-01-21 | 深圳市海滨制药有限公司 | 一种美罗培南的制备方法 |
WO2010104336A2 (ko) * | 2009-03-13 | 2010-09-16 | 주식회사 대웅제약 | 아연 분말을 이용한 메로페넴의 개선된 제조방법 |
CN101914098A (zh) * | 2010-07-20 | 2010-12-15 | 深圳市海滨制药有限公司 | 美罗培南三水合物结晶的制备方法 |
Non-Patent Citations (1)
Title |
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β-Lactams.3.Asymmetric Total Synthesis of New Non-Natural 1β-Methylcarbapenems Exhibiting Strong Antimicrobial Activities and Stability against Human Renal Dehydropeptidase-I;Yoshimitsu Nagao 等;《J. Org. Chem.》;19921231;第57卷(第15期);第4243-4249页 * |
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Address after: 100871, Beijing, Haidian District Cheng Fu Road 298, founder building, 9 floor Patentee after: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee after: PKU HEALTHCARE Corp.,Ltd. Patentee after: PKU HEALTHCARE INDUSTRY Group Address before: 100871, Beijing, Haidian District, Cheng Fu Road, No. 298, Zhongguancun Fangzheng building, 5 floor Patentee before: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee before: SOUTHWEST SYNTHETIC PHARMACEUTICAL Corp.,Ltd. Patentee before: Pku Healthcare Industry Group Co.,Ltd. |
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Effective date of registration: 20221011 Address after: 3007, Hengqin international financial center building, No. 58, Huajin street, Hengqin new area, Zhuhai, Guangdong 519031 Patentee after: New founder holdings development Co.,Ltd. Patentee after: PKU HEALTHCARE Corp.,Ltd. Patentee after: Peking University Medical Management Co.,Ltd. Address before: 100871, Beijing, Haidian District Cheng Fu Road 298, founder building, 9 floor Patentee before: PEKING UNIVERSITY FOUNDER GROUP Co.,Ltd. Patentee before: PKU HEALTHCARE Corp.,Ltd. Patentee before: PKU HEALTHCARE INDUSTRY Group |
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