CN102526391A - Livestock Chinese medicinal composition with refrigerating function and preparation method thereof - Google Patents
Livestock Chinese medicinal composition with refrigerating function and preparation method thereof Download PDFInfo
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- CN102526391A CN102526391A CN2010105906387A CN201010590638A CN102526391A CN 102526391 A CN102526391 A CN 102526391A CN 2010105906387 A CN2010105906387 A CN 2010105906387A CN 201010590638 A CN201010590638 A CN 201010590638A CN 102526391 A CN102526391 A CN 102526391A
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Abstract
The invention relates to a livestock Chinese medicinal composition with a refrigerating function and a preparation method thereof. The Chinese medicinal composition comprises the following components in parts by weight: 30-60 parts of Chinese thorowax root, 30-60 parts of baikal skullcap root, 20-50 parts of pinellia, 30-60 parts of dangshen, 10-30 parts of liquoric root, 30-60 parts of spina date seed, 60-150 parts of an effervescing agent and 20-60 parts of a lubricating agent. The livestock Chinese medicinal composition has the advantages of quick response, freeness from toxic and side effect as well as medicament residues, simplified operation, saving in cultivating cost, convenience for using and high bioavailability.
Description
Technical field
The invention belongs to field of veterinary, especially a kind of poultry with analgesic function is with Chinese medicine composition and preparation method thereof.
Background technology
The domestic animal pathogen is the principal contradiction of disease, the common flu that arrives, constipation, tumor enclosed mass or the like disease, and their morbidity is to be main with pathogen mostly.There is very big drawback again in the mode of conventional companion's material dispensing, causes the medicine responding time to prolong, problems such as treatment cost rising.
Summary of the invention
The object of the present invention is to provide a kind of poultry with analgesic function to use Chinese medicine composition, this Chinese medicine composition onset speed is fast, have no side effect and drug residue, simplifies the operation, and practices thrift aquaculture cost, and easy to use, bioavailability is high.
Another object of the present invention is to provide a kind of method for preparing with poultry of analgesic function with Chinese medicine composition.
The present invention realizes through following technical scheme:
A kind of poultry with analgesic function is used Chinese medicine composition, and its this Chinese medicinal composition and ratio of weight and number thereof are:
Radix Bupleuri 30-60 part;
Radix Scutellariae 30-60 part;
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20-50 part;
Radix Codonopsis 30-60 part;
Radix Glycyrrhizae 10-30 part;
Semen Ziziphi Spinosae 30-60 part;
Effervescent 60-150 part;
Lubricant 20-60 part.
And described effervescent is combined by the wherein a kind of and sodium bicarbonate weight ratio in tartaric acid, citric acid, the adipic acid at 1: 1.
And described lubricant is wherein a kind of in sucralose, erythritol, magnesium stearate, the dodecyl sodium sulfate.
A kind of method for preparing with poultry of analgesic function with Chinese medicine composition, the step of its preparation method is:
(1) take by weighing Radix Bupleuri, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Codonopsis, Radix Glycyrrhizae, Semen Ziziphi Spinosae according to weight proportion, pulverize and mix back decocte with water 3 times, 2 hours for the first time, the second time and each 1 hour for the third time; Merge decoction liquor, filter, filtrating is concentrated into relative density to be 1.20～1.25 and in the time of 80 ℃, to add the 2mol/L hydrochloric acid solution and regulate pH value to 1.0～2.0, is incubated 1 hour; Left standstill 11～13 hours, and filtered, obtain deposition, in deposition, add 6～8 times of water gagings; Form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, adding with the isopyknic concentration of mixed liquor is 90～95% alcoholic solution again; Stirring makes dissolving, filters, and filtrating is with 2mol/L hydrochloric acid solution adjust pH to 2.0; Be incubated 25～35 minutes down at 55～65 ℃, left standstill 10～14 hours, filter; Deposition is washed till pH value to 7.0 with ethanol, waves most ethanol, and it is subsequent use to obtain extract behind the concentrate drying;
(2) extract that takes by weighing in effervescent, lubricant and the step (1) according to weight proportion is pulverized respectively, and the raw material of pulverizing respectively all through abundant mix homogeneously behind 80 mesh sieves, is obtained mixture A;
(3) be binding agent system soft material with mixture A with 50～60% alcoholic solution of 2～4%PVP; Soft material is all processed granule through 10～15 mesh sieves; Under 50～60 ℃, carry out aeration-drying; All process granulate through 20～30 mesh sieves then, the poultry with analgesic function that gets product is used Chinese medicine composition.
Advantage of the present invention and beneficial effect are:
1. originally have Radix Bupleuri, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Codonopsis, Radix Glycyrrhizae, the Semen Ziziphi Spinosae conduct effective Chinese medicinal ingredients of the poultry of analgesic function, have good strengthening vital QI to eliminate pathogenic factors, antipyretic effect with Chinese medicine composition.As the natural Chinese medicines extract, do not have any poisonous and harmful substance simultaneously, can not produce toxic and side effects, more can not exert an influence health to animal body.
2. the poultry that originally has an analgesic function is introduced the effervescent technology in the granulate preparation of this medicine into Chinese medicine composition cleverly; Can make the dispensing treatment more handy; Save a large amount of manpower and materials, the effective ingredient in the medicine is dissolved rapidly and uniformly, be convenient to domestic animal and absorb; Improve bioavailability, can significantly improve the clinical efficacy of medicine.
3. onset speed of the present invention is fast, have no side effect and drug residue, simplifies the operation, and practices thrift aquaculture cost, and easy to use, bioavailability is high.
The specific embodiment
The present invention further details through following examples.Need to prove: following embodiment is illustrative, is not determinate, can not limit protection scope of the present invention with following embodiment.
Radix Bupleuri among the present invention, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Codonopsis, Radix Glycyrrhizae, Semen Ziziphi Spinosae, tartaric acid, citric acid, adipic acid, sodium bicarbonate, sucralose, erythritol, magnesium stearate, dodecyl sodium sulfate all can be bought on market and obtain.
Embodiment 1
A kind of poultry with analgesic function is used Chinese medicine composition, and its Chinese medicinal composition and weight are respectively Radix Bupleuri 30kg; Radix Scutellariae 30kg; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20kg; Radix Codonopsis 30kg; Radix Glycyrrhizae 10kg; Semen Ziziphi Spinosae 30kg; Effervescent 60kg; Lubricant 20kg; Above-mentioned effervescent is made up of citric acid 30Kg and sodium bicarbonate 30Kg, and lubricant is a magnesium stearate.
A kind of method for preparing with poultry of analgesic function with Chinese medicine composition, the step of its preparation method is:
(1) take by weighing Radix Bupleuri, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Codonopsis, Radix Glycyrrhizae, Semen Ziziphi Spinosae according to weight proportion, pulverize and mix back decocte with water 3 times, 2 hours for the first time, the second time and each 1 hour for the third time; Merge decoction liquor, filter, filtrating is concentrated into relative density to be 1.20 and in the time of 80 ℃, to add the 2mol/L hydrochloric acid solution and regulate pH value to 1.0, is incubated 1 hour; Left standstill 11 hours, and filtered, obtain deposition, in deposition, add 6 times of water gagings; Form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, adding with the isopyknic concentration of mixed liquor is 90% alcoholic solution again, and stirring makes dissolving; Filter, filtrating is incubated 25 minutes with 2mol/L hydrochloric acid solution adjust pH to 2.0 down at 55 ℃, leaves standstill 10 hours; Filter, deposition is washed till pH value to 7.0 with ethanol, waves most ethanol, and it is subsequent use to obtain extract behind the concentrate drying;
(2) extract that takes by weighing in effervescent, lubricant and the step (1) according to weight proportion is pulverized respectively, and the raw material of pulverizing respectively all through abundant mix homogeneously behind 80 mesh sieves, is obtained mixture A;
(3) be binding agent system soft material with mixture A with 50% alcoholic solution of 2%PVP; Soft material is all processed granule through 10 mesh sieves; Under 50 ℃, carry out aeration-drying, all process granulate through 20 mesh sieves then, the poultry with analgesic function that gets product is used Chinese medicine composition.
Embodiment 2
A kind of poultry with analgesic function is used Chinese medicine composition, and its Chinese medicinal composition and weight are respectively Radix Bupleuri 60kg; Radix Scutellariae 60kg; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 50kg; Radix Codonopsis 60kg; Radix Glycyrrhizae 30kg; Semen Ziziphi Spinosae 60kg; Effervescent 150kg; Lubricant 60kg; Above-mentioned effervescent is made up of tartaric acid 75Kg and sodium bicarbonate 75Kg, and lubricant is a dodecyl sodium sulfate.
A kind of method for preparing with poultry of analgesic function with Chinese medicine composition, the step of its preparation method is:
(1) take by weighing Radix Bupleuri, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Codonopsis, Radix Glycyrrhizae, Semen Ziziphi Spinosae according to weight proportion, pulverize and mix back decocte with water 3 times, 2 hours for the first time, the second time and each 1 hour for the third time; Merge decoction liquor, filter, filtrating is concentrated into relative density to be 1.25 and in the time of 80 ℃, to add the 2mol/L hydrochloric acid solution and regulate pH value to 2.0, is incubated 1 hour; Left standstill 13 hours, and filtered, obtain deposition, in deposition, add 8 times of water gagings; Form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, adding with the isopyknic concentration of mixed liquor is 95% alcoholic solution again, and stirring makes dissolving; Filter, filtrating is incubated 35 minutes with 2mol/L hydrochloric acid solution adjust pH to 2.0 down at 65 ℃, leaves standstill 14 hours; Filter, deposition is washed till pH value to 7.0 with ethanol, waves most ethanol, and it is subsequent use to obtain extract behind the concentrate drying;
(2) extract that takes by weighing in effervescent, lubricant and the step (1) according to weight proportion is pulverized respectively, and the raw material of pulverizing respectively all through abundant mix homogeneously behind 80 mesh sieves, is obtained mixture A;
(3) be binding agent system soft material with mixture A with 50～60% alcoholic solution of 4%PVP; Soft material is all processed granule through 15 mesh sieves; Under 60 ℃, carry out aeration-drying, all process granulate through 30 mesh sieves then, the poultry with analgesic function that gets product is used Chinese medicine composition.
Embodiment 3
A kind of poultry with analgesic function is used Chinese medicine composition, and its Chinese medicinal composition and weight are respectively Radix Bupleuri 40kg; Radix Scutellariae 40kg; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 30kg; Radix Codonopsis 40kg; Radix Glycyrrhizae 20kg; Semen Ziziphi Spinosae 40kg; Effervescent 100kg; Lubricant 40kg; Above-mentioned effervescent is made up of adipic acid 50Kg and sodium bicarbonate 50Kg, and lubricant is a sucralose.
The step of its preparation method is with embodiment 1.
Embodiment 4
A kind of poultry with analgesic function is used Chinese medicine composition, and its Chinese medicinal composition and weight are respectively Radix Bupleuri 50kg; Radix Scutellariae 50kg; Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 40kg; Radix Codonopsis 50kg; Radix Glycyrrhizae 25kg; Semen Ziziphi Spinosae 50kg; Effervescent 120kg; Lubricant 30kg; Wherein effervescent is made up of adipic acid 60Kg and sodium bicarbonate 60Kg, and lubricant is an erythritol.
The step of its preparation method is with embodiment 1.
The present invention does not need dissolving in advance in application, directly drop into and culture in the domestic animal drinking water, and the per kilogram water body gets final product with the present invention's 1 gram-10 grams.
The clinical practice experiment
1, experimental technique
At the beginning of 2009, my company is that certain cultivation base of periphery, Tianjin provides free the ill domestic animals and fowls of Drug therapy, and follows the tracks of the statistics therapeutic outcome.The domestic animal that alternate attack of chill and fever loss of appetite symptom is arranged is adopted two cover therapeutic schemes and adds up respectively: one group with the present invention's dispensing treatment of drinking water; One group is adopted common Chinese companion material to treat.
2, experimental result
Obtain the result through primary part observation record morbidity rehabilitation situation, therapeutic effect of the present invention is obvious, adopts experimental group cure rate of the present invention than the experimental group that adopts common Chinese companion material and improves 43%, and the treatment cost reduces by 38%.With SPSS12.0 statistics software analysis, behind the administration 3d, treatment group of the present invention and common Chinese companion material matched group cure rate significant difference (p＜0.05).
Claims (4)
1. the poultry with analgesic function is used Chinese medicine composition, it is characterized in that: this Chinese medicinal composition and ratio of weight and number thereof are:
Radix Bupleuri 30-60 part;
Radix Scutellariae 30-60 part;
Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens) 20-50 part;
Radix Codonopsis 30-60 part;
Radix Glycyrrhizae 10-30 part;
Semen Ziziphi Spinosae 30-60 part;
Effervescent 60-150 part;
Lubricant 20-60 part.
2. the poultry with analgesic function according to claim 1 is used Chinese medicine composition, it is characterized in that: described effervescent is combined by the wherein a kind of and sodium bicarbonate weight ratio in tartaric acid, citric acid, the adipic acid at 1: 1.
3. the poultry with analgesic function according to claim 1 is used Chinese medicine composition, it is characterized in that: described lubricant is wherein a kind of in sucralose, erythritol, magnesium stearate, the dodecyl sodium sulfate.
4. method for preparing with poultry of analgesic function with Chinese medicine composition as claimed in claim 1, it is characterized in that: the step of this method for preparing is:
(1) take by weighing Radix Bupleuri, Radix Scutellariae, Rhizoma Pinelliae (processed with Rhizoma Zingiberis Recens), Radix Codonopsis, Radix Glycyrrhizae, Semen Ziziphi Spinosae according to weight proportion, pulverize and mix back decocte with water 3 times, 2 hours for the first time, the second time and each 1 hour for the third time; Merge decoction liquor, filter, filtrating is concentrated into relative density to be 1.20～1.25 and in the time of 80 ℃, to add the 2mol/L hydrochloric acid solution and regulate pH value to 1.0～2.0, is incubated 1 hour; Left standstill 11～13 hours, and filtered, obtain deposition, in deposition, add 6～8 times of water gagings; Form mixed liquor, with 40% sodium hydroxide solution adjust pH to 7.0, adding with the isopyknic concentration of mixed liquor is 90～95% alcoholic solution again; Stirring makes dissolving, filters, and filtrating is with 2mol/L hydrochloric acid solution adjust pH to 2.0; Be incubated 25～35 minutes down at 55～65 ℃, left standstill 10～14 hours, filter; Deposition is washed till pH value to 7.0 with ethanol, waves most ethanol, and it is subsequent use to obtain extract behind the concentrate drying;
(2) extract that takes by weighing in effervescent, lubricant and the step (1) according to weight proportion is pulverized respectively, and the raw material of pulverizing respectively all through abundant mix homogeneously behind 80 mesh sieves, is obtained mixture A;
(3) be binding agent system soft material with mixture A with 50～60% alcoholic solution of 2～4%PVP; Soft material is all processed granule through 10～15 mesh sieves; Under 50～60 ℃, carry out aeration-drying; All process granulate through 20～30 mesh sieves then, the poultry with analgesic function that gets product is used Chinese medicine composition.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105906387A CN102526391A (en) | 2010-12-16 | 2010-12-16 | Livestock Chinese medicinal composition with refrigerating function and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2010105906387A CN102526391A (en) | 2010-12-16 | 2010-12-16 | Livestock Chinese medicinal composition with refrigerating function and preparation method thereof |
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| CN102526391A true CN102526391A (en) | 2012-07-04 |
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- 2010-12-16 CN CN2010105906387A patent/CN102526391A/en active Pending
Patent Citations (13)
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|---|---|---|---|---|
| JP3155271B2 (en) * | 1989-08-03 | 2001-04-09 | 武田薬品工業株式会社 | Yellow containing liquid |
| CN1044760A (en) * | 1989-11-11 | 1990-08-22 | 黑龙江中医学院 | Preparation of injection of Chinese medicines |
| JPH03155271A (en) * | 1989-11-14 | 1991-07-03 | Matsushita Graphic Commun Syst Inc | Image communication equipment |
| JPH0624954A (en) * | 1992-07-08 | 1994-02-01 | Kao Corp | Cosmetic |
| CN1362246A (en) * | 2001-01-08 | 2002-08-07 | 杨孟君 | Nano Bupleuric medicine for regulating Shaoyang and it spreparation |
| CN1493308A (en) * | 2002-07-17 | 2004-05-05 | 江苏康缘药业股份有限公司 | Preparation technology of sugarless small radix bupleuri granular agent |
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Application publication date: 20120704 |