CN102293891B - Chinese medicine for treating cardiovascular disease and preparation method thereof - Google Patents
Chinese medicine for treating cardiovascular disease and preparation method thereof Download PDFInfo
- Publication number
- CN102293891B CN102293891B CN201110251722.0A CN201110251722A CN102293891B CN 102293891 B CN102293891 B CN 102293891B CN 201110251722 A CN201110251722 A CN 201110251722A CN 102293891 B CN102293891 B CN 102293891B
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- medicine
- cardiovarscular
- succinum
- salviae miltiorrhizae
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The invention provides a Chinese medicine for treating cardiovascular disease. The Chinese medicine is mainly characterized by being prepared from the following raw materials in part by weight: 10 to 20 parts of root of red-rooted salvia, 4 to 10 parts of notoginseng root, 3 to 10 parts of Chinese eaglewood, 3 to 10 parts of dragon's blood, 3 to 10 parts of amber and 1 to 3 parts of borneol. The Chinese medicine can be prepared into capsules and tablets, is used for treating coronary heart disease, angina, hyperlipaemia, and atherosclerosis, has the effects of increasing blood provided for heart and softening angiocarpy to radically prevent epidemic factors of cardiovascular disease and the like, and has a good curative effect, and is easy to prepare, and convenient to take.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to Chinese medicine of a kind of Cardiovarscular and preparation method thereof.
Background technology
Cardiovascular disease comprises coronary heart diseases and angina pectoris etc., and coronary heart diseases and angina pectoris is due to coronary insufficiency, and cardiac muscle ischemia sharply, temporary transient, anoxia is caused, belongs to the traditional Chinese medical science " thoracic obstruction " category.Since last century the fifties, the cardiovascular disease such as coronary heart diseases and angina pectoris have become the third-largest death factors of the mankind except cerebrovascular disease, malignant tumor, so, to its control and further investigation, be the emphasis problem in field of medicaments always.
At present, treat the method for coronary heart diseases and angina pectoris with blood vessel dilating, reduction blood glucose viscosity, antiplatelet aggregation, anticoagulations etc. are main, Chinese medicine and Western medicine are all being brought into play effect separately.Traditional Western medicine of application is nitric acid lipid, beta-receptor resistance preparation, calcium antagonist etc., though onset is rapid, all exists larger toxic and side effects, should not take for a long time, and these medicines mostly is symptomatic treatment, in the face of course advancement is without larger effect.Chinese medicine aspect, the effective ingredient onset of conventional tablet and capsule is slow, and bioavailability is lower; Injection is rapid-action, but is not suitable for long-term prescription.In recent years, the good drop pill of market reaction, as FUFANG DANSHEN DIWAN, SUXIAO JIUXIN WAN etc., has been obtained certain clinical application effect, but its indication is more single, cannot meet the needs of clinical various cardiovascular disease.Inventor is by the investigation of the treatment coronary heart diseases and angina pectoris medicine to selling on market, find the related capsule in market, tablet, injection, drop pill etc., main types of drugs mostly is blood circulation promoting and blood stasis dispelling, pain relieving class medicine, it is mainly for the treatment of congestion type coronary heart diseases and angina pectoris, medicine for qi stagnation and blood stasis type is less, therefore need clinically a kind of deficiency that makes up existing medicine for safe, quick-acting, the reliable medicine of qi stagnation and blood stasis type coronary heart diseases and angina pectoris.
Summary of the invention
Inventor is the existing treatment of perception above-mentioned defect as existing in cardiovascular disease such as coronary heart diseases and angina pectoris in the practice of being engaged in for many years Chinese traditional medical diagnose, through the Analysis on Mechanism that cardiovascular disease is produced, contrast traditional treatment cardiovascular disease method, technical problem to be solved by this invention is to provide the Chinese medicine of a kind of good effect, short treating period, the simple Cardiovarscular of making.
Another technical problem to be solved by this invention is to provide a kind of preparation method of Cardiovarscular Chinese medicine.
Solution of the present invention is the understanding to cardiovascular disease and Therapeutic Principle based on motherland's medical science, achieve with reference to modern pharmacological research, in conjunction with applicant's Chinese traditional medical diagnose practice for many years, from motherland's medicine treasure-house, filter out and can improve microcirculation function, increase heart blood supply, softening cardiovascular natural edible-plant medicine, by theory of Chinese medical science prescription, carries and selects the essence and make.
Medicine of the present invention is to be made up of following weight portion raw material Chinese medicine:
Radix Salviae Miltiorrhizae 10-20, Radix Notoginseng 4-10, Lignum Aquilariae Resinatum 3-10 Sanguis Draxonis 3-10, succinum 3-10, Borneolum Syntheticum 1-3.
Medicine of the present invention is preferred through inventor, is made up of following weight portion raw material Chinese medicine:
Radix Salviae Miltiorrhizae 12-16, Radix Notoginseng 6-8, Lignum Aquilariae Resinatum 5-8 Sanguis Draxonis 5-8, succinum 5-8, Borneolum Syntheticum 1-2.
Medicine of the present invention can be prepared into capsule and tablet, and its preparation method is:
By after said medicine mix homogeneously, directly wear into 200 object fine powders, in incapsulating, make the heavy 0.5g of each capsule, then by the capsule installing sterilizing 24 hours under sterilizing lamp, packaging capsule product; Or by after said medicine mix homogeneously, directly wear into 200 object fine powders, add starch, beta-schardinger dextrin-, the carboxymethyl starch sodium in tablet, used, stir, make soft material, put into pelleter and make every tablet of 0.3g tablet, then be dried 3 hours at the temperature of 60 °-70 °, with sterilizing lamp sterilizing 12 hours, packaging tablet product.
In medicine of the present invention, taking Radix Salviae Miltiorrhizae as monarch drug, Radix Salviae Miltiorrhizae, bitter, be slightly cold, GUIXIN, Liver Channel, Radix Salviae Miltiorrhizae activates yang, stasis-dispelling and pain-killing, nourishing blood and promoting blood circulation, blood circulation promoting and blood stasis dispelling.Taking Radix Notoginseng, Lignum Aquilariae Resinatum as ministerial drug, having invigorates blood circulation receives kidney qi effect, wherein, Radix Notoginseng, sweet, micro-hardship, temperature, returns liver, stomach warp, removing stasis to stop bleeding, the analgesic therapy of invigorating blood circulation; Lignum Aquilariae Resinatum, pungent, bitter, tepor, promoting the circulation of QI to relieve pain, during sending down the abnormal ascending QI is adjusted, the kidney warming improving inspiration by invigorating kidney-QI, for QI stagnated by cold, chest and abdomen swelling and pain.Taking Sanguis Draxonis, succinum as adjuvant drug, play promoting blood circulation and detumescence effect, wherein, and Sanguis Draxonis, sweet, salty, flat, GUIXIN, Liver Channel, the analgesic therapy of invigorating blood circulation, dissipating blood stasis for subsidence of swelling; Succinum, sweet, flat, arresting convulsion is calmed the nerves, blood circulation promoting and blood stasis dispelling, inducing diuresis for treating stranguria syndrome.With Borneolum Syntheticum for making medicine, Borneolum Syntheticum, pungent, bitter, be slightly cold, GUIXIN, spleen, lung meridian, the refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.
The present invention selects said medicine to carry out combination and compatibility, monarch synergism, and all medicines share, and have effect of activating YANG and eliminating stagnation, circulation of qi promoting blood stasis dispelling, can improve microcirculation function, increase heart blood supply, softening cardiovascular.Medicine of the present invention is on probation through developing, and coronary heart diseases and angina pectoris, hyperlipidemia, atherosclerosis disease is had to the effect for the treatment of and prevention.
Function cures mainly: for treatment and prevention to coronary heart diseases and angina pectoris, hyperlipidemia, atherosclerosis disease, have no side effect.
Dosage form: medicine of the present invention is capsule and Tabules.
Instructions of taking: medicine of the present invention is oral medicine, while taking capsule formulation medicine, every day 3 times, each 2, warm water delivery service, after the state of an illness is alleviated, day takes 2 times, each 2; While taking tablet form medicine, every day 3 times, each 4, after the state of an illness is alleviated, day takes 2 times, each 4.Medicine of the present invention 30 days is a course for the treatment of, and treatment needs 4-6 the course for the treatment of.
Taboo item: period in a medicine is avoided cold and uncooked food, maror and tobacco and wine.
Clinical trial data
The Chinese medicine of Cardiovarscular of the present invention, through long-time observation on Clinical Application, is accepted cardiovascular disease patient 216 examples for medical treatment, 62 years old patient's mean age, maximum patient is 87 years old, and minimum patient is 41 years old, and male patient has 139 examples, female patient 77 examples, 41-50 year 13 examples, 51-60 year 60 examples, 61-70 year 129 examples, 70 years old above 14 example, method of administration is: while taking capsule formulation medicine, every day 3 times, each 2, warm water delivery service, after the state of an illness is alleviated, day takes 2 times, each 2; While taking tablet form medicine, every day 3 times, each 4, after the state of an illness is alleviated, day takes 2 times, each 4.30 days courses for the treatment of, on average take continuously 4-6 the course for the treatment of, period in a medicine is avoided cold and uncooked food, maror and tobacco and wine.
Clinical criteria: all cases all disappears for diagnostic criteria substantially by clinical symptoms.
The clinical trial cycle: 3 months-6 months
Therapeutic Method: in the situation that patient is voluntary, patient is divided into two groups, treatment group 216 examples, take medicine of the present invention.Matched group 93 examples, are used existing Drug therapy.
Efficacy assessment standard (change and be as the criterion with cardiovascular disease transference cure, electrocardiogram ischemic CT-T):
Cure: clinical symptoms sign disappears, it is normal that ischaemic ECG change recovers, and it is normal that functional activity recovers.
Effective: clinical symptoms sign disappears substantially, electrocardiogram ischemic has obvious change, and it is normal that functional activity recovers.
Effective: the large portion of clinical symptoms sign disappears, and electrocardiogram ischemic changes, and it is normal that functional activity recovers substantially.
Invalid: clinical symptoms sign does not disappear, electrocardiogram ischemic is without obvious change.
Efficacy result: treatment group and matched group curative effect relatively see the following form.
| Group | Case load | Invalid | Effectively | Effective | Cure | Effective percentage | Cure rate |
| Treatment group | 216 | 4 | 21 | 154 | 37 | 98.1% | 17.1% |
| Matched group | 93 | 5 | 17 | 59 | 12 | 94.6% | 12.9% |
Prove by above clinical trial, medicine of the present invention has proved that cardiovascular disease is due to coronary insufficiency, due to cardiac muscle ischemia sharply, temporary transient, anoxia, medicine of the present invention is started with to the ill with this just, improve microcirculation function, increase heart blood supply, softening cardiovascular, fundamentally block the pathogenic factors of cardiovascular disease, obtained beyond thought therapeutic effect.
Detailed description of the invention
Embodiment 1
Medicine of the present invention is to be made up of following weight raw material Chinese medicine:
Radix Salviae Miltiorrhizae 30g, Radix Notoginseng 10, Lignum Aquilariae Resinatum 8g, Sanguis Draxonis 8g, succinum 8g, Borneolum Syntheticum 5g.
Preparation method: after aforementioned proportion Chinese medicine is mixed, directly wear into 200 object fine powders, in incapsulating, make the heavy 0.5g of each capsule, then by the capsule installing sterilizing 24 hours under sterilizing lamp, packaging capsule product; Or by after said medicine mix homogeneously, directly wear into 200 object fine powders, add starch, beta-schardinger dextrin-, the carboxymethyl starch sodium in tablet, used, stir, make soft material, put into pelleter and make every tablet of 0.3g tablet, then be dried 3 hours at the temperature of 60 °-70 °, with sterilizing lamp sterilizing 12 hours, packaging tablet product.
Embodiment 2
Medicine of the present invention is to be made up of following weight raw material Chinese medicine:
Radix Salviae Miltiorrhizae 50, Radix Notoginseng 20g, Lignum Aquilariae Resinatum 15g, Sanguis Draxonis 15g, succinum 15g, Borneolum Syntheticum 3g.
Preparation method: with embodiment 1.
Embodiment 3
Medicine of the present invention is to be made up of following weight raw material Chinese medicine:
Radix Salviae Miltiorrhizae 60g, Radix Notoginseng 35g, Lignum Aquilariae Resinatum 25g, Sanguis Draxonis 25g, succinum 25g, Borneolum Syntheticum 10g.
Preparation method: with embodiment 1.
From 216 cases, take passages some cases below, proof for reference determined curative effect of the present invention.
Case 1. Lu, man, 58 years old, driver, people from Nanyang City, Henan Province, suffers from coronary heart diseases and angina pectoris, cardiac blood supply deficiency disease for many years, though through multi-treatment, poor effect.Take medicine of the present invention after 1 month, on inspection, the related indexes such as whole blood viscosity, plasma viscosity and angina pectoris attacks number of times have remarkable improvement, after take again medicine of the present invention 3 months, clinical symptoms disappears substantially on inspection, indices reaches normal range substantially.
Case 2. Hus, female, 62 years old, people from Nanyang City, Henan Province, 2009 are medical, main suit: precordial pain, both sides of the chest distending pain, uncomfortable in chest, cardiopalmus 6 months, anxious state of mind or outbreak when tired, can alleviate containing disease after nitroglycerine tablets whenever, and health is weak, Mental fatigue drowsirness, uncomfortable in chest, abundant expectoration, dizziness, vomiting and nausea is often done.Electrocardiogram prompting coronary insufficiency, angina pectoris attacks is frequent, myocardium sensation of oppression over the chest with shortness of breath, dizziness and tinnitus, Western medicine diagnose: hypertension, coronary heart diseases and angina pectoris, Chinese medical discrimination is qi depression to blood stasis.Take Chinese medicine of the present invention after 20 days, remission, took after 3 months, and precordial pain, both sides of the chest distending pain, headache, dizzy transference cure, through paying a return visit, are not sent out so far.
Case 3. Lee, female, 71 years old, people from Nanyang City, Henan Province, Nanyang Yi Jia hospital is moved in patient and in JIUYUE, 2009 morbidity, through nuclear magnetic resonance check, show that heart coronary artery is atherosis, two lower limb atherosclerosis, underwent coronary contrast examination shows, heart anterior descending branch infraction, though carry out operative treatment, after this, occur unstable angina pectoris, blood pressure is high always.Through inventor's diagnosis and treatment, patient's deep-slow pulse is unable, hypertension, thick blood fat, angina pectoris, and with back cardiac reflex district's pain and asthma, through taking medicine of the present invention after 20 days, back cardiac reflex district's pain and symptoms of asthma disappear, take after 70 days, have rosy cheeks, repeatedly check blood pressure, pulse is all normal, mental attitude is good, after 100 days through nuclear magnetic resonance check, show heart hat structure, function is all normal, two lower limb atherosclerosis are also restored, coronarography inspection shows that heart anterior descending branch infraction obviously alleviates, rear return visit, so far more than 1 year, do not fall ill again.
Case 4. Zhangs, man, 67 years old, retired employees, Nanyang City, Henan Province watt people from shop, patient's private prosecution: nervous after tired, dyspnea, hypertension, hyperlipidemia is had a surplus for 10 years, show myocardial ischemia through Electrocardioscopy, coronarography shows sclerosis, according to clinical symptoms, diagnosis shows that patient suffers from coronary heart disease, myocardial ischemia, take medicine of the present invention after 60 days, blood pressure, blood fat is steady, nervous, dyspnea symptom is eliminated, take and reexamine for 120 days, Electrocardioscopy shows no longer ischemia of cardiac muscle, coronarography shows sclerosis elimination, pay a return visit so far 2 years state of an illness do not recur.
Case 5. grandsons, man, 62 years old, retired employees, people from Xinye County, Nanyang City, Henan Province, patient diagnosed before 5 years and suffers from coronary heart diseases and angina pectoris, and private prosecution her heart rate is uneven, nervous, cardiopalmus, though after one hospitalize of Xinye County the state of an illness alleviate, after again recurrence, daily medicine is continuous.Introduce through other people, take medicine of the present invention after 30 days, nervous, cardiopalmus symptom is eliminated, and heart rate is also neat steady, and angina pectoris symptom remarkable improvement after 60 days is taken angina pectoris symptom after 90 days and disappeared, and after 120 days, through checking, disease is eliminated, so far existing morbidity again for 3 years.
Case 6. rivers, man, 51 years old, people from Zhenping County, Nanyang City, Henan Province, private prosecution is nervous, cardiopalmus, arrhythmia, heart strand pain, breathes hard, unable, have a strong impact on working and learning, through taking medicine of the present invention 2 months, nervous, cardiopalmus, arrhythmia transference cure, after 4 months, heart strand pain disappears, and physical recovery is normal on inspection, and within 2 years so far, the state of an illness does not recur.
Above-described embodiment is described the preferred embodiment of the present invention; not scope of the present invention is limited; design under the prerequisite of spirit not departing from the present invention; various distortion and improvement that those of ordinary skill in the art have done technical scheme of the present invention, within all should falling into protection scope of the present invention.
Claims (6)
1. a Chinese medicine for Cardiovarscular, is characterized in that being made up of following weight portion raw material Chinese medicine:
Radix Salviae Miltiorrhizae 10-20, Radix Notoginseng 4-10, Lignum Aquilariae Resinatum 3-10 Sanguis Draxonis 3-10, succinum 3-10, Borneolum Syntheticum 1-3.
2. the Chinese medicine of Cardiovarscular as claimed in claim 1, is characterized in that being made up of following weight portion raw material Chinese medicine:
Radix Salviae Miltiorrhizae 12-16, Radix Notoginseng 6-8, Lignum Aquilariae Resinatum 5-8 Sanguis Draxonis 5-8, succinum 5-8, Borneolum Syntheticum 1-2.
3. the Chinese medicine of Cardiovarscular as claimed in claim 2, is characterized in that being made up of following weight raw material Chinese medicine:
Radix Salviae Miltiorrhizae 30g, Radix Notoginseng 10, Lignum Aquilariae Resinatum 8g, Sanguis Draxonis 8g, succinum 8g, Borneolum Syntheticum 5g.
4. the Chinese medicine of Cardiovarscular as claimed in claim 2, is characterized in that being made up of following weight raw material Chinese medicine:
Radix Salviae Miltiorrhizae 50, Radix Notoginseng 20g, Lignum Aquilariae Resinatum 15g, Sanguis Draxonis 15g, succinum 15g, Borneolum Syntheticum 3g.
5. the Chinese medicine of Cardiovarscular as claimed in claim 2, is characterized in that being made up of following weight raw material Chinese medicine:
Radix Salviae Miltiorrhizae 60g, Radix Notoginseng 35g, Lignum Aquilariae Resinatum 25g, Sanguis Draxonis 25g, succinum 25g, Borneolum Syntheticum 10g.
6. the preparation method of Cardiovarscular Chinese medicine as arbitrary in claim 1-5, it is characterized in that, by after said medicine mix homogeneously, directly wearing into 200 object fine powders, in incapsulating, make the heavy 0.5g of each capsule, again by the capsule installing sterilizing 24 hours under sterilizing lamp, packaging capsule product; Or by after said medicine mix homogeneously, directly wear into 200 object fine powders, add starch, beta-schardinger dextrin-, the carboxymethyl starch sodium in tablet, used, stir, make soft material, put into pelleter and make every tablet of 0.3g tablet, then be dried 3 hours at the temperature of 60 °-70 °, with sterilizing lamp sterilizing 12 hours, packaging tablet product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110251722.0A CN102293891B (en) | 2011-08-30 | 2011-08-30 | Chinese medicine for treating cardiovascular disease and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110251722.0A CN102293891B (en) | 2011-08-30 | 2011-08-30 | Chinese medicine for treating cardiovascular disease and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102293891A CN102293891A (en) | 2011-12-28 |
| CN102293891B true CN102293891B (en) | 2014-11-12 |
Family
ID=45354723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201110251722.0A Expired - Fee Related CN102293891B (en) | 2011-08-30 | 2011-08-30 | Chinese medicine for treating cardiovascular disease and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102293891B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102805814B (en) * | 2012-08-23 | 2014-02-12 | 北京修成药业有限公司 | Application of Qian mountain blood activating paste to preparation of medicines for preventing and treating atherosclerosis |
| CN111000894A (en) * | 2019-12-26 | 2020-04-14 | 广东罗浮山国药股份有限公司 | Application of compound red sage root preparation in treating metabolic syndrome |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1421242A (en) * | 2002-12-23 | 2003-06-04 | 北京采瑞医药有限公司 | Compound red sage capsule for treating cardiac and cerebral vascular diseases and its prepn process |
| CN102119962A (en) * | 2010-01-07 | 2011-07-13 | 天津天士力现代中药资源有限公司 | Extract for preventing and treating angina pectoris and preparation method and application thereof |
-
2011
- 2011-08-30 CN CN201110251722.0A patent/CN102293891B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1421242A (en) * | 2002-12-23 | 2003-06-04 | 北京采瑞医药有限公司 | Compound red sage capsule for treating cardiac and cerebral vascular diseases and its prepn process |
| CN102119962A (en) * | 2010-01-07 | 2011-07-13 | 天津天士力现代中药资源有限公司 | Extract for preventing and treating angina pectoris and preparation method and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 国家药典委员会编.复方丹参滴丸.《中国药典2000年版（一部）新增与修订内容汇编 （初稿）》.1999,97-98. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102293891A (en) | 2011-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100382839C (en) | Chinese-medicinal composition for treating coronary heart disease | |
| CN102293891B (en) | Chinese medicine for treating cardiovascular disease and preparation method thereof | |
| CN104013919A (en) | Traditional Chinese medicine for treating angina pectoris | |
| CN101816712B (en) | Chinese medicinal composition for treating trigeminal neuralgia | |
| CN102133288B (en) | Chinese herbal preparation for curing angina | |
| CN102908513A (en) | Application of traditional Chinese medicine composition in medicine for treating arrhythmia | |
| CN101596302A (en) | A kind of treatment treating coronary heart disease and angina pectoris and preparation method thereof | |
| CN101167838B (en) | Traditional Chinese medicinal preparation for treating coronary heart disease and angina pectoris and its preparing process | |
| CN102579804B (en) | Chinese medicine for treating stenocardia | |
| CN101991829B (en) | Medicament for treating stomach illness | |
| CN102008539B (en) | Medicinal composition for treating diseases such as viral myocarditis and dilated cardiomyopathy and preparation process thereof | |
| CN102210807B (en) | Application of traditional Chinese medicine composition in preparation of medicaments for treating angina pectoris | |
| CN101632783B (en) | Application of Chinese medicinal composition in preparing medicament for treating cor pulmonale | |
| CN103127413B (en) | Pharmaceutical preparation for treating coronary diseases | |
| CN111388623B (en) | Traditional Chinese medicine for treating coronary heart disease | |
| CN103028094A (en) | Chinese patent medicine for treating coronary heart disease | |
| CN102961540A (en) | Medicine for treating coronary heart disease and preparation method for same | |
| CN105770520A (en) | Medicine preparation used for treating coronary heart disease and application thereof | |
| CN103191326B (en) | Medicine preparation for treating coronary heart diseases | |
| CN105708989A (en) | Pharmaceutical preparation for treating and improving myocardial infarction and application of pharmaceutical preparation | |
| CN105168653A (en) | Traditional Chinese medicine composition used for treating coronary heart disease | |
| CN104042676B (en) | It is a kind of to treat Chinese medicine composition of coronary heart disease and preparation method thereof | |
| CN104800574A (en) | Chinese drug preparation for treating coronary heart disease | |
| CN104096112A (en) | Traditional Chinese medicine composition for treating angina pectoris | |
| CN103520468B (en) | A kind of Chinese medicine for the treatment of viral myocarditis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C53 | Correction of patent for invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Shi Xiuyan Inventor after: Ma Yongsheng Inventor after: Guo Pei Inventor before: Shi Xiuyan |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: SHI XIUYAN TO: SHI XIUYAN MA YONGSHENG GUO PEI |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141112 Termination date: 20190830 |