CN102292070A - 具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 - Google Patents
具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 Download PDFInfo
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- CN102292070A CN102292070A CN2009801550699A CN200980155069A CN102292070A CN 102292070 A CN102292070 A CN 102292070A CN 2009801550699 A CN2009801550699 A CN 2009801550699A CN 200980155069 A CN200980155069 A CN 200980155069A CN 102292070 A CN102292070 A CN 102292070A
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- amlodipine
- compositions
- losartan
- preparation
- stabilizing agent
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Landscapes
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Abstract
Description
时间(min) | 流动相A% | 流动相B% |
0 | 80 | 20 |
10 | 40 | 60 |
11 | 80 | 20 |
15 | 80 | 20 |
Claims (11)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201610294905.3A CN105998017A (zh) | 2009-01-23 | 2009-06-05 | 具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 |
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2009-0005840 | 2009-01-23 | ||
KR20090005840 | 2009-01-23 | ||
KR10-2009-0036011 | 2009-04-24 | ||
KR1020090036011A KR101232296B1 (ko) | 2009-01-23 | 2009-04-24 | 안정성이 향상된 암로디핀 및 로자탄을 함유하는 고형 약제학적 조성물 |
PCT/KR2009/003028 WO2010085027A1 (en) | 2009-01-23 | 2009-06-05 | Solid pharmaceutical composition comprising amlodipine and losartan with improved stability |
Related Child Applications (1)
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CN201610294905.3A Division CN105998017A (zh) | 2009-01-23 | 2009-06-05 | 具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 |
Publications (1)
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CN102292070A true CN102292070A (zh) | 2011-12-21 |
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CN200980155068.4A Active CN102292085B (zh) | 2009-01-23 | 2009-02-13 | 包含氨氯地平和氯沙坦的固体药物组合物及其制备方法 |
CN201610294905.3A Pending CN105998017A (zh) | 2009-01-23 | 2009-06-05 | 具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 |
CN2009801550699A Pending CN102292070A (zh) | 2009-01-23 | 2009-06-05 | 具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 |
CN200980155067.XA Expired - Fee Related CN102292084B (zh) | 2009-01-23 | 2009-12-28 | 包含氨氯地平和氯沙坦的固体药物组合物 |
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CN200980155068.4A Active CN102292085B (zh) | 2009-01-23 | 2009-02-13 | 包含氨氯地平和氯沙坦的固体药物组合物及其制备方法 |
CN201610294905.3A Pending CN105998017A (zh) | 2009-01-23 | 2009-06-05 | 具有提高的稳定性的包含氨氯地平和氯沙坦的固体药物组合物 |
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CN200980155067.XA Expired - Fee Related CN102292084B (zh) | 2009-01-23 | 2009-12-28 | 包含氨氯地平和氯沙坦的固体药物组合物 |
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US (3) | US9161933B2 (zh) |
EP (3) | EP2413931B1 (zh) |
JP (3) | JP5658172B2 (zh) |
KR (2) | KR101232296B1 (zh) |
CN (4) | CN102292085B (zh) |
AR (3) | AR070897A1 (zh) |
AU (3) | AU2009338267B2 (zh) |
BR (3) | BRPI0924136B8 (zh) |
CA (3) | CA2749903C (zh) |
CL (1) | CL2011001781A1 (zh) |
CO (3) | CO6361905A2 (zh) |
CR (3) | CR20110450A (zh) |
DO (3) | DOP2011000231A (zh) |
EA (3) | EA020103B1 (zh) |
EC (1) | ECSP11011253A (zh) |
ES (3) | ES2580777T3 (zh) |
HK (1) | HK1163539A1 (zh) |
HN (2) | HN2011002022A (zh) |
IL (3) | IL214146A0 (zh) |
JO (2) | JO2981B1 (zh) |
MA (3) | MA33056B1 (zh) |
MX (3) | MX349221B (zh) |
MY (3) | MY173823A (zh) |
NI (3) | NI201100145A (zh) |
NZ (3) | NZ594738A (zh) |
PE (4) | PE20100559A1 (zh) |
SA (1) | SA110310070B1 (zh) |
SG (3) | SG173044A1 (zh) |
TW (3) | TWI404534B (zh) |
UA (3) | UA102721C2 (zh) |
UY (2) | UY32388A (zh) |
WO (3) | WO2010085014A1 (zh) |
ZA (3) | ZA201106161B (zh) |
Cited By (6)
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CN104394865A (zh) * | 2012-04-17 | 2015-03-04 | 韩国联合制药株式会社 | 稳定性提高的并包含氨氯地平和氯沙坦的复合组合物 |
CN104610130A (zh) * | 2015-01-22 | 2015-05-13 | 华东理工常熟研究院有限公司 | 氨氯地平-棕榈酸离子液体及其制备方法和用途 |
CN107260735A (zh) * | 2017-07-25 | 2017-10-20 | 合肥华方医药科技有限公司 | 生物利用度提高的二氢吡啶类药物组合物 |
CN107308158A (zh) * | 2017-07-28 | 2017-11-03 | 合肥华方医药科技有限公司 | 一种提高非洛地平生物利用度的药物组合物 |
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CN108156807A (zh) * | 2015-06-30 | 2018-06-12 | 韩美药品株式会社 | 含有氨氯地平、氯沙坦和瑞舒伐他汀的药物复合制剂 |
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EA020103B1 (ru) | 2009-01-23 | 2014-08-29 | Ханми Сайенс Ко., Лтд. | Твердая фармацевтическая композиция, содержащая амлодипин и лозартан, и способ ее получения |
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JP6041591B2 (ja) * | 2011-09-13 | 2016-12-14 | 大日本住友製薬株式会社 | イルベサルタンとアムロジピンまたはその塩を含有する安定化された医薬組成物 |
KR101907881B1 (ko) * | 2011-12-30 | 2018-12-11 | 한미약품 주식회사 | 로자탄, 암로디핀 및 히드로클로로티아자이드를 포함하는 고정 용량 조합 제형 |
CN102600146B (zh) * | 2012-04-11 | 2014-10-08 | 兆科药业(合肥)有限公司 | 一种盐酸乐卡地平和氯沙坦钾复方制剂及其制备方法 |
JP6160263B2 (ja) * | 2012-06-07 | 2017-07-12 | 大正製薬株式会社 | ロキソプロフェン含有医薬組成物 |
KR101506148B1 (ko) * | 2013-09-24 | 2015-03-26 | 대봉엘에스 주식회사 | 직접 타정할 수 있는 암로디핀 및 로사르탄을 포함하는 약제학적 조성물, 및 이에 의해 제조된 정제 |
WO2015072700A1 (en) * | 2013-11-15 | 2015-05-21 | Hanmi Pharm. Co., Ltd. | Composite formulation comprising tadalafil and amlodipine |
KR20150056443A (ko) * | 2013-11-15 | 2015-05-26 | 한미약품 주식회사 | 타다라필 및 암로디핀을 포함하는 복합제제 |
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KR102369607B1 (ko) | 2014-09-30 | 2022-03-03 | 한미약품 주식회사 | 암로디핀 및 로잘탄을 포함하는 고형 약제학적 조성물 |
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CN104394865A (zh) * | 2012-04-17 | 2015-03-04 | 韩国联合制药株式会社 | 稳定性提高的并包含氨氯地平和氯沙坦的复合组合物 |
CN104394865B (zh) * | 2012-04-17 | 2016-11-09 | 韩国联合制药株式会社 | 稳定性提高的包含氨氯地平和氯沙坦的组合物 |
CN104610130A (zh) * | 2015-01-22 | 2015-05-13 | 华东理工常熟研究院有限公司 | 氨氯地平-棕榈酸离子液体及其制备方法和用途 |
CN108156807A (zh) * | 2015-06-30 | 2018-06-12 | 韩美药品株式会社 | 含有氨氯地平、氯沙坦和瑞舒伐他汀的药物复合制剂 |
CN107260735A (zh) * | 2017-07-25 | 2017-10-20 | 合肥华方医药科技有限公司 | 生物利用度提高的二氢吡啶类药物组合物 |
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