CN102258043A - Germicide composition containing protioconazole - Google Patents
Germicide composition containing protioconazole Download PDFInfo
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- CN102258043A CN102258043A CN201110237522XA CN201110237522A CN102258043A CN 102258043 A CN102258043 A CN 102258043A CN 201110237522X A CN201110237522X A CN 201110237522XA CN 201110237522 A CN201110237522 A CN 201110237522A CN 102258043 A CN102258043 A CN 102258043A
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- prochloraz
- carbendazim
- thiophanate
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Abstract
The invention relates to a germicide composition containing protioconazole. The germicide composition comprises an active component A and an active component B, wherein the active component A is protioconazole, the active component B is one of thiophanatemethyl, carbendazim and prochloraz, the weight ratio of the active component A to the active component B is (1:80): (80:1), and the germicide composition can be prepared into wettable powder, water dispersible granules, suspending agents, suspending emulsion, EW (emulsion in water), and microemulsion for preventing and curing diseases such as powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust disease, sclerotiniose, virus disease, anthracnose, gray mold, ring spot, bakanae disease, rice blast, early blight, green mold, stem-end rot, blue mold, helminthosporium leaf spot, banana freckle, damping off and the like, and has the characteristics of less application quantity, rain water washout resistance and obvious synergism.
Description
Technical field
The invention belongs to technical field of pesticide, relate to a kind of application of bactericidal composition on crop pest that contains prothioconazoles.
Technical background
Prothioconazoles, English name: prothioconazole molecular formula: C
14H
15Cl
2N
3The OS chemical name: (RS)-2-[2-(1-chlorine cyclopropyl)-3-(2-chlorphenyl)-2-hydroxypropyl]-2,4-dihydro-1,2,4-triazole-3-thioketones.
Prothioconazoles is a kind of new triazolinones systemic fungicide, as a kind of demethylation inhibitor (DMI), plays the demethylation effect on 14-or-24 methylene lanostenols of precursor-lanosterol of suppressing sterol in the fungi.By a large amount of field control effectiveness tests, the result shows that prothioconazoles not only has good safety to crop, and preventing disease theraping effect is good, and volume increase is obvious, compares with the triazole type biocide agent, and prothioconazoles has the more sterilization of wide spectrum lives in, and the lasting period is long.
Thiophanate-methyl (thiophanate-methyl), molecular formula: C
12H
14N
4O
4S
2, chemical name: 1,2-pair-(3-carbethoxyl group-α-ghiourea group) benzene, thiophanate-methyl belongs to benzimidazole, is a kind of broad spectrum activity systemic fungicide, can prevent and treat the various crop disease, has interior suction, prevention and therapeutic action.It is converted into carbendazim in plant corpus, the formation of spindle influences cell division in the mitosis of interference bacterium.
Carbendazim (carbendazim), molecular formula: C
9H
9N
3O
2, chemical name: N-(2-benzimidazolyl) methyl carbamate, the carbendazim high-efficiency low-toxicity, effective to sac fungi and imperfect fungus, invalid to oomycetes and bacterial disease, have protection and therapeutic action.The mechanism of action is the formation of imitative hammer body in the mitosis of disturbing bacterium, thereby influences cell division.
Prochloraz (prochloraz), molecular formula: C
15H
16Cl
3N
3O
2, chemical name: N-propyl group-N-[α-(2,4, the 6-Trichlorophenoxy)-1H-imidazoles-1-formamide, Prochloraz belongs to the imidazoles broad-spectrum germicide.The various crop disease that causes for sac fungi and imperfect fungus has special efficacy.Cause effect by the biosynthesis that suppresses sterol.Though do not have a systemic action, it has certain conductive performance.
In the real process of agricultural production, preventing and treating the problem that disease is easy to generate most is the drug-fast generation of germ.The different cultivars composition carries out composite, is to prevent and treat the very common method of resistance germ.Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism.In most cases, the composite effect of agricultural chemicals all is an additive effect, and the seldom composite of synergistic effect really arranged, especially synergistic effect very obviously, synergy ratio very high composite just still less.Through inventor research, find prothioconazoles and active component B is composite mutually, good synergistic effect is arranged within the specific limits, and relevant composite about prothioconazoles and thiophanate-methyl, carbendazim, Prochloraz, do not see relevant report at present at home and abroad as yet.
Summary of the invention
The objective of the invention is to propose a kind of have synergistic function, use cost is low, preventive effect the is good bactericidal composition that contains prothioconazoles.
The present invention is achieved through the following technical solutions:
A kind of bactericidal composition that contains prothioconazoles is characterized in that: the weight ratio of active components A and active component B is 1: 80～80: 1, and described active components A is a prothioconazoles, and active component B is selected from a kind of in thiophanate-methyl, carbendazim, the Prochloraz.
The described bactericidal composition that contains prothioconazoles is characterized in that: the weight ratio of prothioconazoles and active component B is 1: 60～60: 1.
The described bactericidal composition that contains prothioconazoles is characterized in that: the weight ratio of prothioconazoles and active component B is 32: 1～1: 32.
The described bactericidal composition that contains prothioconazoles is characterized in that: the weight ratio of prothioconazoles and thiophanate-methyl is 8: 1～1: 16.
The described bactericidal composition that contains prothioconazoles is characterized in that: the weight ratio of prothioconazoles and carbendazim is 8: 1～1: 16.
The described bactericidal composition that contains prothioconazoles is characterized in that: the weight ratio of prothioconazoles and Prochloraz is 8: 1～1: 16.
The described bactericidal composition that contains prothioconazoles is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
The described bactericidal composition that contains prothioconazoles is used to prevent and treat the application of disease on grass family class crop, vegetables, rape, legume crop and the fruit tree.
Described application, it is characterized in that described disease comprises: powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust, stalk break, virus disease, anthracnose, gray mold, ring spot, bakanae disease, rice blast, early blight, green mould, blossom-end rot, penicilliosis, helminthosporium leaf spot, scab, damping off.
Amount of application when the content of active component depends on independent use in the present composition also depends on the mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with the target fungi.Usually active weight percentage is 0.5%～90% of a gross weight in the composition, and preferable is 5%～85%.According to different preparation types, the active component content scope is different.Usually, liquid preparation contains 1%～70% active substance by weight, preferably is 5%～50%; Solid pharmaceutical preparation contains 5%～85% active substance by weight, preferably is 10%～80%.
At least contain a kind of surfactant in the bactericidal composition of the present invention, the dispersion of active component in water when being beneficial to use.Surface-active contents is 5%～30% of a total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of bactericidal composition of the present invention is known in those skilled in the art: can be selected from dispersant, wetting agent, thickener or the defoamer one or more.According to different dosage form, can also contain stabilizing agent known in those skilled in the art, antifreeze etc. in the preparation.
Bactericidal composition of the present invention can be processed into acceptable forms on any agricultural chemicals on demand.Wherein preferred dosage form is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
When making wetting powder, composition comprises following constituent content: prothioconazoles 1%～80%, active component B1%～80%, dispersant 5%～10%, wetting agent 2%～10%, filler 8%～91%.
The former medicine of prothioconazoles, the former medicine of active component B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, promptly can be made into the wetting powder product of the present composition.
When making water dispersible granules, composition comprises following constituent content: prothioconazoles 1%～80%, active component B1%～80%, dispersant 3%～12%, wetting agent 1%～8%, disintegrant 1%～10%, binding agent 1%～8%, filler 10%～92%.
The former medicine of prothioconazoles, the former medicine of active component B, dispersant, wetting agent, disintegrant, filler etc. are obtained the particle diameter that needs through comminution by gas stream together, add other auxiliary agents such as binding agent again, obtain the preparation materials.It is interior through after granulation and the drying to expect that product are quantitatively sent the fluidized bed granulation dryer to, makes the water dispersible granules product of the present composition.
When making suspending agent, composition comprises following constituent content: prothioconazoles 1%～40%, active component B1%～40%, dispersant 2%～10%, wetting agent 2%～10%, defoamer 0.1%～1%, thickener 0.1%～2%, antifreeze 0.1%～8%, stabilizing agent 0.05%～3%, deionized water adds to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in the above-mentioned prescription are mixed through high speed shear, add the former medicine of prothioconazoles, the former medicine of active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make the suspending agent product of the present composition.
Comprise following constituent content when composition is made suspension emulsion: prothioconazoles 1%～40%, active component B1%～40%, emulsifier 2%～10%, dispersant 2%～10%, defoamer 0.1%～2%, thickener 0.1%～2%, antifreeze 0.1%～8%, stabilizing agent 0.05%～3%, water add to 100%.
Dispersant, defoamer, thickener, antifreeze, stabilizing agent in the above-mentioned prescription are mixed through high speed shear, add the former medicine of active component B, ball milling is 2～3 hours in ball mill, make diameter of particle all below 5 μ m, make active component B suspending agent, then with the former medicine of prothioconazoles, emulsifier and various auxiliary agent with the direct emulsification of high speed agitator in suspending agent, make the suspension emulsion product of the present composition.
When making aqueous emulsion, composition comprises following constituent content: prothioconazoles 1%～40%, active component B1%～40%, solvent 2%～10%, emulsifier 2%～12%, dispersant 2%～10%, co-emulsifier 0.2%～5%, antifreeze 0.1%～8%, defoamer 0.1%～2%, thickener 0.1%～2%, deionized water adds to 100%.
Be dissolved into even oil phase with having former medicine, solvent, emulsifier, co-emulsifier to add together in the above-mentioned prescription, making.With deionized water, dispersant, antifreeze,, defoamer, thickener mix, and becomes the homogeneous water, under high-speed stirred, water slowly splashed into oil phase, makes the finely disseminated aqueous emulsion product of the present composition.
When making microemulsion, composition comprises following constituent content: prothioconazoles 1%～40%, active component B 1%～40%, and emulsifier 5%～15%, solvent 2%～10%, antifreeze 5%～10%, stabilizing agent 0.5%～3%, deionized water adds to 100%.
Above-mentioned prescription Central Plains medicine, solvent, emulsifier are added in the mother liquor modulation kettle, make even oil phase, deionized water, antifreeze etc. is mixed injection product modulation kettle,, mix and make the transparent or semitransparent microemulsion product of the present composition through high-speed stirred.
Beneficial effect of the present invention: (1) present composition active component prothioconazoles and effective active composition B belong to the bactericide of two kinds of different mechanisms of action, and both are mixed mutually and can produce conflict; (2) present composition has good synergistic effect within the specific limits, and preventive effect is higher than single agent, and dosage is little; (3) with an organic solvent dosage is little in the present invention, is difficult for producing poisoning, is convenient to transportation and storage; (4) present composition has enlarged fungicidal spectrum, and diseases such as crop powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust, stalk break, virus disease, anthracnose, gray mold, ring spot, bakanae disease, rice blast, early blight, green mould, blossom-end rot, penicilliosis, helminthosporium leaf spot, scab, damping off are all had special efficacy.
Embodiment
To further instruction of the present invention, the percentage among the embodiment is weight ratio below in conjunction with embodiment, but the present invention is not limited thereto.
Application Example one
Example 1 70% prothioconazoles thiophanate-methyl wetting powder
Prothioconazoles 5%, thiophanate-methyl 65%, lignosulfonates 5.6%, spaonin powder 5%, diatomite add to 100%, and mixture carries out comminution by gas stream, make 70% prothioconazoles thiophanate-methyl wetting powder.
Example 2 80% prothioconazoles thiophanate-methyl wetting powders
Prothioconazoles 5%, thiophanate-methyl 75%, lignosulfonates 5%, soapberry powder 5%, white carbon add to 100%, and mixture carries out comminution by gas stream, make 80% prothioconazoles thiophanate-methyl wetting powder.
Example 3 60% prothioconazoles thiophanate-methyl water dispersible granules
Prothioconazoles 10%, thiophanate-methyl 50%, naphthalene sulfonic acid-formaldehyde condensation product 6%, Nekal BX 4.5%, sodium bicarbonate 2%, kaolin add to 100%, the mixed 60% prothioconazoles thiophanate-methyl water dispersible granules that gets.
Example 4 75% prothioconazoles thiophanate-methyl water dispersible granules
Prothioconazoles 5%, thiophanate-methyl 70%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, spaonin powder 5%, bentonite add to 100%, the mixed 75% prothioconazoles thiophanate-methyl water dispersible granules that gets.
Example 5 50% prothioconazoles thiophanate-methyl suspending agents
Prothioconazoles 10%, thiophanate-methyl 40%, aryl phenol polyoxyethylene succinate sulfonate 4%, lauryl sodium sulfate 5%, C
10～20Saturated fat acids 1.5%, gum Arabic 3.5%, ethylene glycol 1.5%, deionized water add to 100%, the mixed 50% prothioconazoles thiophanate-methyl suspending agent that gets.
Example 6 35% prothioconazoles thiophanate-methyl suspending agents
Prothioconazoles 5%, thiophanate-methyl 30%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 5.5%, lauryl sodium sulfate 6%, C
10～20Saturated fat acids 1.2%, sodium phosphate trimer 1.8%, propane diols 1.5%, deionized water add to 100%, the mixed 35% prothioconazoles thiophanate-methyl suspending agent that gets.
Example 7 40% prothioconazoles thiophanate-methyl suspension emulsions
Prothioconazoles 4%, thiophanate-methyl 36%, naphthalene sulfonic acid-formaldehyde condensation product 5%, soapberry powder 4%, polyvinylpyrrolidone 2%, OP series 5%, glycerine 3%, C
10～20Saturated fat acids 0.8%, water add to 100%, through the mixed 40% prothioconazoles thiophanate-methyl suspension emulsion that gets.
Example 8 45% prothioconazoles thiophanate-methyl suspension emulsions
Prothioconazoles 9%, thiophanate-methyl 36%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, lauryl sodium sulfate 4%, gum Arabic 1.5%, By series 5%, ethylene glycol 1.6%, silicone oil 0.5%, water add to 100%, through the mixed 45% prothioconazoles thiophanate-methyl suspension emulsion that gets.
Example 9 24% prothioconazoles thiophanate-methyl microemulsions
Prothioconazoles 3%, thiophanate-methyl 21%, tween 6%, alkylbenzenesulfonate 5%, phenethyl phenol polyethenoxy ether phosphate 6%, xanthans 3%, propane diols 5%, silicone oil 1.5%, deionized water supplies 100%, the mixed 24% prothioconazoles thiophanate-methyl microemulsion that gets.
Example 10 10% prothioconazoles thiophanate-methyl microemulsions
Prothioconazoles 9%, thiophanate-methyl 1%, N-pyrrolidones 4%, ethylene glycol 5%, polyvinyl alcohol 4%, tween series 4%, alkylbenzenesulfonate 3%, silicone oil 1.5%, deionized water supplies 100%, makes 10% prothioconazoles thiophanate-methyl microemulsion.
Example 11 16% prothioconazoles thiophanate-methyl aqueous emulsions
Prothioconazoles 4%, thiophanate-methyl 12%, phenethyl phenol polyethenoxy ether 5%, alkylbenzenesulfonate 5%, OP series 5%, glycerine 4%, gum Arabic 5%, silicone oil 1.5%, deionized water supplies 100%, makes 16% prothioconazoles thiophanate-methyl aqueous emulsion.
Example 12 12% prothioconazoles thiophanate-methyl aqueous emulsions
Prothioconazoles 11%, thiophanate-methyl 1%, castor oil polyoxyethylene ether 5%, OP series 5%, gelatin 1.5%, glycerine 5%, sodium chloride 2%, C
8～10Aliphatic alcohols 0.5%, deionized water supplies 100%, makes 12% prothioconazoles thiophanate-methyl aqueous emulsion.
Example 13 78% prothioconazoles carbendazol wettable powders
Prothioconazoles 6%, carbendazim 72%, aryl phenol polyoxyethylene succinate sulfonate 6%, silkworm excrement 4%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 78% prothioconazoles carbendazol wettable powder.
Example 14 65% prothioconazoles carbendazol wettable powders
Prothioconazoles 5%, carbendazim 60%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 5%, spaonin powder 4%, diatomite add to 100%, and mixture carries out comminution by gas stream, makes 65% prothioconazoles carbendazol wettable powder.
Example 15 64% prothioconazoles carbendazim water dispersing granules
Prothioconazoles 8%, carbendazim 56%, polycarboxylate 6%, lauryl sodium sulfate 5%, ammonium sulfate 3%, diatomite add to 100%, the mixed 64% prothioconazoles carbendazim water dispersing granule that gets.
Example 16 70% prothioconazoles carbendazim water dispersing granules
Prothioconazoles 10%, carbendazim 60%, lignosulfonates 6%, neopelex 6%, bentonite add to 100%, the mixed 70% prothioconazoles carbendazim water dispersing granule that gets.
Example 17 40% prothioconazoles carbendazim suspending agents
Prothioconazoles 10%, carbendazim 30%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 6%, silkworm excrement 5%, C
10～20Saturated fat acids 1.8%, xanthans 1.8%, propane diols 3%, deionized water add to 100%, the mixed 40% prothioconazoles carbendazim suspending agent that gets.
Example 18 45% prothioconazoles carbendazim suspending agents
Prothioconazoles 9%, carbendazim 36%, the phonetic formaldehyde condensation products sulphate 6% of alkylphenol-polyethenoxy, lauryl sodium sulfate 5%, silicone compound 1.5%, gum Arabic 2.5%, ethylene glycol 3%, deionized water add to 100%, the mixed 45% prothioconazoles carbendazim suspending agent that gets.
Example 19 45% prothioconazoles carbendazim suspension emulsions
Prothioconazoles 5%, carbendazim 40%, naphthalene sulfonic acid-formaldehyde condensation product 6%, Nekal BX 6%, silicone compound 2%, triphenyl phosphite 2%, polyvinylpyrrolidone 2%, Nongru-700 #5%, ethylene glycol 1.5%, water add to 100%, the aforementioned formula material is mixed, promptly make 45% prothioconazoles carbendazim suspension emulsion.
Example 20 38% prothioconazoles carbendazim suspension emulsions
Prothioconazoles 8%, carbendazim 30%, alkylphenol-polyethenoxy are phonetic 5%, neopelex 5%, silicone oil 1.5%, polyvinylpyrrolidone 1.5%, tween series 5%, polyethylene glycol 3%, water add to 100%, the aforementioned formula material is mixed, promptly make 38% prothioconazoles carbendazim suspension emulsion.
Example 21 20% prothioconazoles carbendazim microemulsions
Prothioconazoles 19%, carbendazim 1%, styrene polyoxyethylene ether ammonium sulfate salt 6%, cyclohexanone 3%, glycerine 8%, silicone 1.5%, deionized water adds to 100%, through the mixed 20% prothioconazoles carbendazim microemulsion that gets.
Example 22 18% prothioconazoles carbendazim microemulsions
Prothioconazoles 15%, carbendazim 3%, By series 8%, ethylene glycol monomethyl ether 3%, polyethylene glycol 5%, C
8～10Aliphatic alcohols 1%, deionized water adds to 100%, through the mixed 18% prothioconazoles carbendazim microemulsion that gets.
Example 23 45% prothioconazoles carbendazim aqueous emulsions
Prothioconazoles 44%, carbendazim 1%, N-octylpyrrolidone 5%, farming breast 1800
#6%, calcium chloride 3%, glycerine 4%, silicone 1.5%, deionized water adds to 100%, through the mixed 45% prothioconazoles carbendazim aqueous emulsion that gets.
Example 24 22% prothioconazoles carbendazim aqueous emulsions
Prothioconazoles 11%, carbendazim 11%, N, dinethylformamide 5%, alkyl biphenyl ether disulfonic acid magnesium salts 5%, butanols 3%, ethylene glycol 5%, C
8～10Aliphatic alcohols 1.5%, deionized water adds to 100%, through the mixed 22% prothioconazoles carbendazim aqueous emulsion that gets.
Example 25 78% prothioconazoles Prochloraz wetting powders
Prothioconazoles 1%, Prochloraz 77%, polycarboxylate 7%, soapberry powder 4%, attapulgite add to 100%, and mixture carries out comminution by gas stream, make 78% prothioconazoles Prochloraz wetting powder.
Example 26 56% prothioconazoles Prochloraz wetting powders
Prothioconazoles 6%, Prochloraz 50%, naphthalene sulfonic acid-formaldehyde condensation product 6%, silkworm excrement 5%, starch add to 100%, and mixture carries out comminution by gas stream, make 56% prothioconazoles Prochloraz wetting powder.
Example 27 65% prothioconazoles Prochloraz water dispersible granules
Prothioconazoles 10%, Prochloraz 55%, polyoxyethylene carboxylate 6%, neopelex 5%, bentonite add to 100%, the mixed 65% prothioconazoles Prochloraz water dispersible granules that gets.
Example 28 48% prothioconazoles Prochloraz water dispersible granules
Prothioconazoles 6%, Prochloraz 42%, lignosulfonates 6%, lauryl sodium sulfate 6%, sodium bicarbonate 2%, kaolin add to 100%, the mixed 48% prothioconazoles Prochloraz water dispersible granules that gets.
Example 29 40% prothioconazoles Prochloraz suspending agents
Prothioconazoles 10%, Prochloraz 30%, polycarboxylate 6%, lauryl sodium sulfate 5%, silicone oil 1.5%, gum Arabic 1.5%, glycerine 1.5%, deionized water adds to 100%, the mixed 40% prothioconazoles Prochloraz suspending agent that gets.
Example 30 25% prothioconazoles Prochloraz suspending agents
Prothioconazoles 20%, Prochloraz 5%, aryl phenol polyoxyethylene succinate sulfonate 6%, lauryl sodium sulfate 6%, silicone compound 1.5%, polyvinylpyrrolidone 1.5%, polyethylene glycol 1.5%, deionized water adds to 100%, the mixed 25% prothioconazoles Prochloraz suspending agent that gets.
Example 31 45% prothioconazoles Prochloraz suspension emulsions
Prothioconazoles 15%, Prochloraz 30%, polyoxyethylene carboxylate 6%, lauryl sodium sulfate 5%, polyvinylpyrrolidone 1.5%, polyethylene glycol 2%, C
10～20Saturated fat acids 0.8%, agricultural newborn 600#6%, water add to 100%, the mixed 45% prothioconazoles Prochloraz suspension emulsion that gets.
Example 32 28% prothioconazoles Prochloraz suspension emulsions
Prothioconazoles 21%, Prochloraz 7%, aryl phenol polyoxyethylene succinate sulfonate 7%, soapberry powder 5%, sodium phosphate trimer 1.5%, ethylene glycol 1.5%, C
10～20Saturated fat acids 0.5%, OP series 6%, water add to 100%, the mixed 28% prothioconazoles Prochloraz suspension emulsion that gets.
Example 33 40% prothioconazoles Prochloraz microemulsions
Prothioconazoles 2%, Prochloraz 38%, alkylphenol polyoxyethylene phosphate 6%, N-pyrrolidones 5%, castor oil polyoxyethylene ether 5%, gelatin 2%, glycerine 3%, silicone oil 0.5%, deionized water supplies 100%, the mixed 40% prothioconazoles Prochloraz microemulsion that gets.
Example 34 30% prothioconazoles Prochloraz microemulsions
Prothioconazoles 15%, Prochloraz 15%, N-pyrrolidones 5%, ethylene glycol 5%, polyvinyl alcohol 2%, tween series 5%, alkylbenzenesulfonate 3%, silicone oil 0.8%, deionized water supplies 100%, makes 30% prothioconazoles Prochloraz microemulsion.
Example 35 48% prothioconazoles prochloraz aqueous emulsions
Prothioconazoles 47%, Prochloraz 1%, alkylbenzenesulfonate 4%, alkylphenol polyoxyethylene 5%, OP series 7%, propane diols 4%, polyvinyl alcohol 2%, silicone oil 0.8%, deionized water supplies 100%, makes 48% prothioconazoles prochloraz aqueous emulsion.
Example 36 36% prothioconazoles prochloraz aqueous emulsions
Prothioconazoles 9%, Prochloraz 27%, fatty alcohol-polyoxyethylene ether 6%, alkylbenzenesulfonate 4%, agricultural newborn 33#5%, polyethylene glycol 5%, gelatin 2%, silicone oil 0.8%, deionized water supplies 100%, makes 36% prothioconazoles prochloraz aqueous emulsion.
Wetting powder the key technical indexes of the present invention:
Water dispersible granules the key technical indexes of the present invention:
Suspending agent the key technical indexes of the present invention:
Suspension emulsion the key technical indexes of the present invention:
Aqueous emulsion the key technical indexes of the present invention:
Microemulsion the key technical indexes of the present invention:
The embodiment of the invention is the method that adopts Toxicity Determination and field trial to combine.Pass through Toxicity Determination earlier, the synergy ratio (SR) after clear and definite two kinds of medicaments are composite by a certain percentage, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect, on this basis, carry out field trial again.
Prothioconazoles and active component B (B be selected from thiophanate-methyl, carbendazim, the Prochloraz a kind of) are composite to the crop pest Toxicity Determination.
After the effective inhibition concentration scope of each medicament was determined in prerun, each medicament was established 5 dosage respectively by active constituent content and is handled, and established the clear water contrast.Carry out with reference to " agricultural chemicals indoor bioassay test rule bactericide ", adopt the mycelial growth rate method to measure the virulence of medicament the crop germ.Measure colony diameter with the right-angled intersection method behind the 72h, calculate and respectively handle clean amount of growth, mycelial growth inhibition rate.
Clean amount of growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, tries to achieve virulence regression equation (y=a+bx) with method of least squares, and calculates the EC of every kind of medicament thus
50Value.Calculate the different proportioning synergy ratios (SR) of two medicaments according to the Wadley method simultaneously, SR＜0.5 is an antagonism, and 0.5≤SR≤1.5 are summation action, and SR＞1.5 are synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively active component prothioconazoles and active component B (thiophanate-methyl, carbendazim, Prochloraz) shared ratio in combination;
A is a prothioconazoles;
B is a kind of in thiophanate-methyl, carbendazim, the Prochloraz.
Implementation of an application example two:
Prothioconazoles and thiophanate-methyl are composite to the stalk break Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of prothioconazoles and thiophanate-methyl and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 1 prothioconazoles and thiophanate-methyl and composite toxicity test analysis of results table thereof to stalk break
As shown in Table 1, prothioconazoles and thiophanate-methyl are to the EC of stalk break
50Be respectively 4.05mg/L and 13.65mg/L.Prothioconazoles and thiophanate-methyl proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that prothioconazoles and thiophanate-methyl were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, especially when the two proportioning during at 4: 1 to 1: 16, wherein prothioconazoles and thiophanate-methyl proportioning were at 4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: the 10 pair of stalk break and virus disease synergistic effect are more remarkable, synergy ratio SR maximum when prothioconazoles and thiophanate-methyl weight ratio are 1: 4 wherein, synergistic effect is the most obvious.
Implementation of an application example three:
Prothioconazoles and carbendazim are composite to the wheat powdery mildew Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining prothioconazoles and carbendazim active compound and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 2 prothioconazoles and carbendazim and composite toxicity test analysis of results table thereof to wheat powdery mildew
As shown in Table 2, prothioconazoles and carbendazim are to the EC of wheat powdery mildew
50Be respectively 3.98mg/L and 13.57mg/L.Prothioconazoles and carbendazim proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that prothioconazoles and carbendazim were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, especially working as prothioconazoles and carbendazim proportioning is that synergistic effect in 4: 1 to 1: 16 is the most obvious, wherein the two proportioning was at 4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: 10 o'clock more remarkable to powdery mildew and smut synergistic effect, especially when the proportioning of prothioconazoles and carbendazim during at 1: 4, synergy ratio SR maximum, synergistic effect is the most remarkable.
Implementation of an application example four
Prothioconazoles and Prochloraz are composite to the citrus common green mold Toxicity Determination.
Test medicine provides by Shaanxi agricultural chemicals Co., Ltd of U.S. nation.
Experimental scheme: effective inhibition concentration scope of determining the former medicine of prothioconazoles and Prochloraz and the two different proportioning mixture through preliminary experiment.
Toxicity test result
Table 3 prothioconazoles and Prochloraz and composite toxicity test analysis of results table thereof to citrus common green mold
As shown in Table 3, prothioconazoles and Prochloraz are to the EC of citrus common green mold
50Be respectively 3.87mg/L and 6.24mg/L.Prothioconazoles and Prochloraz proportioning were at 80: 1 to 1: 80 o'clock, synergy ratio SR is all greater than 1.5, illustrating that prothioconazoles and Prochloraz were mixed in the scope at 80: 1 to 1: 80 all shows synergistic effect, especially synergistic effect is the most remarkable when prothioconazoles and Prochloraz proportioning are 8: 1 to 1: 16, wherein the two proportioning was at 4: 1,3: 1,2: 1,1: 1,1: 2,1: 3,1: 4,1: 5,1: 6,1: 7,1: 8,1: 9,1: the 10 pair of green mould and penicilliosis preventive effect are best, especially when the proportioning of prothioconazoles and Prochloraz during at 1: 2, synergy ratio SR maximum, synergistic effect is the most obvious.
Application Example five prothioconazoles and thiophanate-methyl and the composite control rice blast test of pesticide effectiveness thereof
This experimental establishment is in suburb, Jingzhou City, Hebei province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 40% prothioconazoles wetting powder (autogamy), 36% thiophanate-methyl suspending agent (commercial).
The investigation rice blast state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 4 prothioconazoles and thiophanate-methyl and the composite control rice blast test of pesticide effectiveness thereof
As can be seen from Table 4, can effectively prevent and treat rice blast after prothioconazoles and thiophanate-methyl are composite, control efficiency all is better than the preventive effect of single agent, find through the test people, the composite back of prothioconazoles and thiophanate-methyl is better to preventing and treating the rice sheath blight disease preventive effect, 30 days preventive effects reach 85% behind the medicine, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example six prothioconazoles and carbendazim and the composite early blight of tomato test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Weinan City suburb, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 40% prothioconazoles wetting powder (autogamy), 80% carbendazim water dispersing granule (commercial).
The investigation early blight of tomato state of an illness before the medicine, in the dispenser for the first time of state of an illness initial stage, dispenser in per 7 days once is total to dispenser 2 times.Investigated disease index respectively and calculated preventive effect in 3 days, 14 days, 30 days after the dispenser for the second time.Experimental result is as follows:
Table 5 prothioconazoles and carbendazim and the composite early blight of tomato test of pesticide effectiveness of preventing and treating thereof
As can be seen from Table 5, can effectively prevent and treat early blight of tomato after prothioconazoles and carbendazim are composite, control efficiency all is better than the preventive effect of single agent, find through the test people, the melon anthracnose preventive effect of the composite back control of prothioconazoles and carbendazim is also better, and 30 back preventive effects reach more than 85% behind the medicine, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Application Example seven prothioconazoles and Prochloraz and the composite bakanae disease of rice test of pesticide effectiveness of preventing and treating thereof
This experimental establishment is in Mianyang City suburb, Sichuan Province, and test medicine is researched and developed, provided by Shaanxi agricultural chemicals Co., Ltd of U.S. nation, contrast medicament 40% prothioconazoles wetting powder (autogamy), 25% prochloraz aqueous emulsion (commercial).
Investigation bakanae disease of rice disease index before the medicine, in the their early stage dispenser, every dispenser on the 7th once, dispenser is 2 times altogether, investigates disease indexs in 3 days, 14 days, 30 days after the dispenser for the second time and calculates preventive effect.Experimental result is as follows:
Table 6 prothioconazoles, the composite bakanae disease of rice test of pesticide effectiveness of preventing and treating of Prochloraz
As can be seen from Table 6, can effectively prevent and treat bakanae disease of rice after prothioconazoles and Prochloraz are composite, control efficiency all is better than the preventive effect of single agent, find through the test people, the composite back of prothioconazoles and Prochloraz is better to preventing and treating the Hemintho-sporum leaf spot of rice plants preventive effect, and 30 days preventive effects reach 85% behind the medicine, and the preventive effect phase is long.In the test scope of medication, the target crop is had no adverse effects.
Claims (8)
1. bactericidal composition that contains prothioconazoles, it is characterized in that: the weight ratio of active components A and active component B is 1: 80～80: 1, and described active components A is a prothioconazoles, and active component B is selected from a kind of in thiophanate-methyl, carbendazim, the Prochloraz.
2. the bactericidal composition that contains prothioconazoles according to claim 1 is characterized in that: the weight ratio of prothioconazoles and active component B is 1: 60～60: 1.
3. the bactericidal composition that contains prothioconazoles according to claim 2 is characterized in that: the weight ratio of prothioconazoles and thiophanate-methyl is 8: 1～1: 16.
4. the bactericidal composition that contains prothioconazoles according to claim 2 is characterized in that: the weight ratio of prothioconazoles and carbendazim is 8: 1～1: 16.
5. the bactericidal composition that contains prothioconazoles according to claim 2 is characterized in that: the weight ratio of prothioconazoles and Prochloraz is 8: 1～1: 16.
6. according to each described bactericidal composition that contains prothioconazoles in the claim 1 to 5, it is characterized in that: composition is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion.
7. the bactericidal composition that contains prothioconazoles according to claim 6 is used to prevent and treat the application of disease on grass family class crop, vegetables, rape, legume crop and the fruit tree.
8. application according to claim 7, it is characterized in that described disease comprises: powdery mildew, banded sclerotial blight, fusarium wilt, leaf spot, rust, stalk break, virus disease, anthracnose, gray mold, ring spot, bakanae disease, rice blast, early blight, green mould, blossom-end rot, penicilliosis, helminthosporium leaf spot, scab, damping off.
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| CN102669114A (en) * | 2012-04-23 | 2012-09-19 | 广东中迅农科股份有限公司 | Pesticide combination containing prothioconazole and hymexazol |
| CN102823609A (en) * | 2012-09-03 | 2012-12-19 | 江苏辉丰农化股份有限公司 | Purpose of sterilization agent composition for preventing and treating rice diseases |
| CN103168785A (en) * | 2013-03-22 | 2013-06-26 | 江苏七洲绿色化工股份有限公司 | Ternary compound sterilizing composition containing trifloxystrobin and application of sterilizing composition |
| CN103609596A (en) * | 2013-12-05 | 2014-03-05 | 京博农化科技股份有限公司 | Sterilizing composition of prothioconazole and pyrimidine nucleoside antibiotic |
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| CN104604906A (en) * | 2015-01-13 | 2015-05-13 | 江苏省农业科学院 | Application of prothioconazole/carbendazim compound bactericide in controlling gibberellic disease |
| CN104621160A (en) * | 2013-11-15 | 2015-05-20 | 南京华洲药业有限公司 | Sterilization composition containing prothioconazole and carbendazim and application thereof |
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| CN1642423A (en) * | 2002-03-21 | 2005-07-20 | 巴斯福股份公司 | Fungicidal mixtures |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1642423A (en) * | 2002-03-21 | 2005-07-20 | 巴斯福股份公司 | Fungicidal mixtures |
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| CN102669114B (en) * | 2012-04-23 | 2015-12-16 | 广东中迅农科股份有限公司 | A kind of prothioconazoles that contains is with the composition pesticide of hymexazo |
| CN102669114A (en) * | 2012-04-23 | 2012-09-19 | 广东中迅农科股份有限公司 | Pesticide combination containing prothioconazole and hymexazol |
| CN102823609A (en) * | 2012-09-03 | 2012-12-19 | 江苏辉丰农化股份有限公司 | Purpose of sterilization agent composition for preventing and treating rice diseases |
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| CN104604920A (en) * | 2013-11-05 | 2015-05-13 | 南京华洲药业有限公司 | Sterilization composition containing prochloraz nantokite and triazole bactericide as well as application thereof |
| WO2015070567A1 (en) * | 2013-11-12 | 2015-05-21 | 南京华洲药业有限公司 | Fungicidal composition containing prothioconazole and prochloraz manganese salt and use thereof |
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| CN104642367A (en) * | 2013-11-15 | 2015-05-27 | 南京华洲药业有限公司 | Bactericidal composition containing prothioconazole and prochloraz and application thereof |
| CN103609596A (en) * | 2013-12-05 | 2014-03-05 | 京博农化科技股份有限公司 | Sterilizing composition of prothioconazole and pyrimidine nucleoside antibiotic |
| CN103651562A (en) * | 2013-12-30 | 2014-03-26 | 孙蒙蒙 | Sterilization insecticidal combination containing prothioconazole |
| CN103651562B (en) * | 2013-12-30 | 2016-08-17 | 青岛青知企业管理咨询有限公司 | A kind of Fungicidal insecticidal composition containing prothioconazoles |
| CN103918693A (en) * | 2014-03-31 | 2014-07-16 | 海利尔药业集团股份有限公司 | Bactericidal composition containing prothioconazole and prochloraz |
| CN104604906A (en) * | 2015-01-13 | 2015-05-13 | 江苏省农业科学院 | Application of prothioconazole/carbendazim compound bactericide in controlling gibberellic disease |
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| CN106417343A (en) * | 2016-09-13 | 2017-02-22 | 江苏丘陵地区镇江农业科学研究所 | Application of fungicidal composition containing prochloraz |
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