CN102027987B - Metconazole-containing pesticide composition - Google Patents
Metconazole-containing pesticide composition Download PDFInfo
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- CN102027987B CN102027987B CN201010614877.1A CN201010614877A CN102027987B CN 102027987 B CN102027987 B CN 102027987B CN 201010614877 A CN201010614877 A CN 201010614877A CN 102027987 B CN102027987 B CN 102027987B
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Abstract
The invention discloses a pesticide composition, which comprises metconazole and one of triazole bactericides such as flusilazole, epoxiconazole, tetraconazole, tricyclazole and flutriafol, wherein the weight part ratio of the two active ingredients in the pesticide composition is 80:1-1:80. The pesticide composition at least comprises a surfactant to contribute to dispersing the active ingredients in water during application. The bactericide composition has protecting, treating and killing activities, can be used for various crops, such as wheat, rice, vegetables, fruit trees and the like, and prevents and controls various plant diseases caused by pathogenic bacteria of aseomycotina, basidiomycolina and deuteromycotina.
Description
Technical field
The invention belongs to disinfectant use in agriculture field, relate to a kind of preparation and application of the composition pesticide containing metconazole.
Background technology
Metconazole (Metconazole), for Japanese Wu Yu chemical company is in the trendy triazole bactericidal agent of early 1990s exploitation, molecular formula: C
17h
22clN
3o, structural formula:
Metconazole is C-14 demethylation enzyme inhibitor in ergosterol biosynthesis.Although the mechanism of action is the same with other triazole bactericidal agents, activity profile difference is larger.Two kinds of isomer have bactericidal activity, but cis activity is higher than trans.The antifungal spectrum of metconazole is very extensive, and active splendid.Metconazole field is used and cereal septoria musiva, fusarium and handle rest fungus are planted to disease is had remarkable effect.Metconazole is compared with traditional biocide agent, and dosage is extremely low and prevent and treat cereal to plant disease scope very wide.
Metconazole single dose is used for a long time, easily makes disease develop immunity to drugs, and causes the problem that dosage strengthens, preventive effect reduces, the lasting period shortens, and is unfavorable for environment sustainable development.And that the active ingredient of the different mechanisms of action is carried out is composite, be to delay the disease conventional method that develops immunity to drugs, and according to the effect in production application, judge this composite be synergistic effect or antagonism.Complex role is significantly filled a prescription, and can obviously improve preventive effect, greatly reduces the dosage of agricultural chemicals, also can expand fungicidal spectrum, improves germicidal efficiency.
Summary of the invention
The object of the invention is to propose a kind of generation or delaying drug resistance speed that can prevent disease drug resistance, the composition pesticide containing metconazole that use cost is low, preventive effect is good.
The composition pesticide that the present invention proposes contains A, two kinds of active components of B.
Active component A is metconazole.
Active component B is selected from following any one triazole bactericidal agent: Flusilazole, epoxiconazole, tetraconazole, tricyclazole, Flutriafol.
In triazole bactericidal agent chemical constitution, common feature is on main chain, to contain hydroxyl (ketone group), substituted-phenyl and 1,2,4-triazole group compound.This class medicament, except to oomycetes non-activity in Mastigomycotina, all has activity to the pathogen of Ascomycotina, Basidiomycotina and Deuteromycotina, and its mechanism of action, for to affect sterols biosynthesis, is damaged somatic cells film function.
Described Flusilazole (flusilazole), molecular formula is C
16h
15f
2n
3si, chemical name: two (4-fluorophenyl) methyl (1H-1, the support of 2,4-triazol-1-yl methylene) silane.Triazole bactericidal agent.This medicine is mainly the biosynthesis that destroys and stop the cell membrane important composition composition ergosterol of germ, causes cell membrane not form, and makes germ dead.In antithetical phrase, due to the germ of Gammaproteobacteria, Basidiomycetes and Fungi Imperfecti, disease is effective, invalid to oomycetes.
Described epoxiconazole (epoxiconazole), molecular formula is C
17h
13clFN
3o, chemical name: (2RS, 3SR)-3-(2-chlorphenyl)-2-(4-fluorophenyl)-2-[(1H1,2,4-triazol-1-yl) methyl] oxirane.
Described tetraconazole (tetraconazole), chemical name: 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl) propyl group 1,1,2,2-tetrafluoro ethyl ether.It is sterol demethylation inhibitor.Due to absorption in having well, therefore can promptly be absorbed by plants, and in conducted inside; There is good protection and therapeutic activity.
Described tricyclazole (tricyclazole), molecular formula: C
9h
7n
3s, chemical name: 5-methyl isophthalic acid, 2,4-triazol (3,4-b) benzothiazole.Be a kind of protectiveness triazole bactericidal agent that interior absorption is stronger that has, can by rice root, stem, leaf, be absorbed rapidly, and be transported to each portion of rice strain.Tricyclazole antiscour power is strong, and spray medicine is met rain after one hour do not need the medicine that fills spray.Be mainly to suppress spore germination and adhere to spore to form, thereby effectively stop germ to invade and reduce the generation of magnaporthe grisea spore.
Described Flutriafol (flutriafol), molecular formula is C
16h
13f
2n
3o, chemical name: α-(2-fluorophenyl)-α-(4-fluorophenyl)-1H-1,2,4-triazole-1-ethanol.There is interior absorption, in plant corpus, conduct, disease is had to protection and therapeutic action.Can prevent and treat cereal crop powdery mildew, Helminthosporium, Puccinia, shell pin Pseudomonas pathogen, also can be cooked seed treatment, prevents and treats soil-borne disease and seed-borne disease.Cereal powdery mildew is had to special efficacy.
The ratio of weight and number of A, two kinds of active components of B is 80: 1～1: 80, and preferred ratio of weight and number is 40: 1～1: 40, and preferred ratio of weight and number is: 20: 1～1: 20.
The described composition pesticide containing metconazole, is characterized in that: the ratio of weight and number of active component Flusilazole and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The described composition pesticide containing metconazole, is characterized in that: the ratio of weight and number of active component tetraconazole and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The described composition pesticide containing metconazole, is characterized in that: the ratio of weight and number of active component tricyclazole and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The described composition pesticide containing metconazole, is characterized in that: the ratio of weight and number of active component Flutriafol and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The described composition pesticide containing metconazole, is characterized in that: the ratio of weight and number of active component epoxiconazole and metconazole is 10: 1～1: 10, and further preferred ratio of weight and number is 5: 1～1: 5.
The amount of application when content of active component depends on independent use in the present composition, also depends on mixed ratio and the synergistic effect degree of a kind of compound and another kind of compound, and the while is also relevant with target fungi.Conventionally in composition, active weight percentage is gross weight 1～90%, is preferably 10%～80%.According to different preparation types, active component content scope is different.Conventionally, liquid preparation contains 1～70% active substance by weight, is preferably 5～50%; Solid pharmaceutical preparation contains 5～85% active substance by weight, is preferably 10～80%.
In composition pesticide of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use.Surface-active contents is 5～30% of total formulation weight amount, and surplus is solid or liquid diluent.
The selected surfactant of composition pesticide of the present invention is known in those skilled in the art: can be selected from one or more in dispersant, wetting agent, emulsifier or defoamer.According to different dosage form, in preparation, can also contain disintegrant known in those skilled in the art, antifreeze etc.
Composition of the present invention can be by user before use through dilution or directly use.Its preparation can be prepared by common processing method known in those skilled in the art, after being about to active substance and mixing with liquid flux or solid carrier, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, binding agent, defoamer etc.
Composition pesticide of the present invention, can be processed into acceptable formulation on any agricultural chemicals on demand, and wherein the excellent formulation of selecting is wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment.
When making wetting powder, composition comprises following constituent content: active constituent A 1～80%, active constituent B 1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%.
Active constituent A, active constituent B, dispersant, wetting agent, filler are mixed, in mixed cylinder, mix, after airslide disintegrating mill is pulverized, mix again, can be made into wetting powder product of the present invention.
When making water dispersible granules, composition comprises following constituent content: active constituent A1～80%, active constituent B1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～90%.
Active constituent A, active constituent B, dispersant, wetting agent, disintegrant, filler etc. are obtained to the particle diameter needing through air-flow crushing together, then add other auxiliary agents such as binding agent, obtain the materials of granulating.By item quantitatively send in fluidized bed granulation dryer through granulation and dry after, make water dispersible granules product of the present invention.
When making suspending agent, composition comprises following constituent content: active constituent A1～40%, active constituent B1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%.
Dispersant, wetting agent, defoamer, thickener, antifreeze in above-mentioned formulation material are mixed through high speed shear, add active constituent A, active constituent B, in ball mill, ball milling is 2～3 hours, makes diameter of particle all below 5 μ m, makes suspending agent product of the present invention.
When making aqueous emulsion, composition comprises following constituent content: active constituent A1～40%, active constituent B1～40%, solvent 1～30%, emulsifier 1～15%, co-emulsifier 0～8%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, deionized water are supplied surplus.
Above-mentioned formulation material is mixed, active ingredient, solvent, emulsifier, co-emulsifier are added together, make to be dissolved into even oil phase; Water, antifreeze, thickener, defoamer are mixed, become homogeneous water.Under high-speed stirred, water is added to oil phase, make aqueous emulsion product of the present invention.
When making microemulsion, composition comprises following constituent content: active constituent A1～40%, active constituent B1～40%, solvent 1～30%, emulsifier 3～20%, co-emulsifier 0～12%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, stabilizing agent 0～4%, deionized water is supplied surplus.
The former medicine of active constituent A and the former medicine of active constituent B are dissolved in the homogenizer that solvent and cosolvent are housed; After emulsifier, stabilizing agent and antifreeze, water being joined in the homogenizer that above-mentioned solution is housed, give strong mixing and homogenize, finally obtain the as clear as crystal microemulsion product of the present invention of outward appearance.
Described dispersant is selected from alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol-polyethenoxy is phonetic, aliphatic amine polyoxyethylene is phonetic, polyoxyethylene carboxylate, one or more during ester polyoxyethylene is phonetic.
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, soapberry powder.
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, aluminium chloride.
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol.
Described defoamer is selected from: silicone, C
8～10aliphatic alcohols, C
10～20one or more in saturated fat acids (as capric acid) and acid amides, silicone oil, silicone compound.
Described emulsifier is selected from one or more in alkyl benzene sulfonate calcium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 506#, 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80,602#;
Described co-emulsifier is one or more in butanols, isobutanol, dodecanol-1, tetradecanol-1, octadecanol-1;
Described solvent is selected from one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, vegetable oil, dimethyl formamide, acetonitrile, polyethylene glycol, pyrrolidones, solvent N-chain alkyl pyrrolidones;
Described preservative is selected from one or more in formaldehyde, sodium salicylate, Sodium Benzoate, dichlorophen;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, precipitated calcium carbonate.
Microbicide compositions of the present invention has protection concurrently, treats and roots out activity, can be used for various crop such as wheat, paddy rice, vegetables, fruit tree etc., the microbial plant disease of cause of disease of control capsule bacterium subphylum, Basidiomycotina and Deuteromycotina.Fallen leaves spot disease, anthracnose, leaf spot, white rot, powdery mildew, rust, banded sclerotial blight, rice blast are all had to special efficacy.
Composition of the present invention has following advantage:
(1) said composition shows significant synergistic effect in certain ratio range, has both improved protection effect, has reduced mu dosage and cost, has expanded again fungicidal spectrum;
(2), because each active component in said composition does not exist the problem of cross resistance, so the application of said composition can reach and delay the drug-fast generation of pathogen and development, the result of use that contributes to extend this medicament, reduces pesticide resistance and produces probability;
(3) improved safety, being mixed will be lower on the impact of environment, safer.
Embodiment
Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is ratio of weight and number, but the present invention is not limited thereto.
The embodiment of the present invention is the method that adopts Toxicity Determination and field trial to combine.
Implementation of an application example one: Toxicity Determination
Metconazole and active constituent B (B be selected from triazole bactericidal agent tetraconazole, Flusilazole, tricyclazole, Flutriafol, epoxiconazole a kind of) are composite to target fungus Toxicity Determination
Test medicine provides by Shaanxi Mei Bang agricultural chemicals Co., Ltd.
After the effective inhibition concentration scope of each medicament is determined in prerun, each medicament is established respectively 5 dosage by active constituent content and is processed, and establishes clear water contrast.With reference to < < farm-chemical indoor determination test rule bactericide > >, carry out, adopt mycelial growth rate method to measure the virulence of medicament to target fungus.After 72h, by right-angled intersection method, measure colony diameter, calculate and respectively process net growth, mycelial growth inhibition rate.
Net growth (mm)=measurement colony diameter-5
Mycelial growth inhibition rate is converted into probit value (y), and liquor strength (μ g/mL) converts logarithm value (x) to, with method of least squares, tries to achieve virulence regression equation (y=a+bx), and calculates thus the EC of every kind of medicament
50value.According to Wadley method, calculate the different proportioning synergy ratio (SR) of two medicaments, SR < 0.5 is antagonism simultaneously, and 0.5≤SR≤1.5 are summation action, and SR > 1.5 is synergistic effect.Computing formula is as follows:
Wherein: a, b are respectively metconazole and active constituent B (triazole bactericidal agent tetraconazole, Flusilazole, tricyclazole, Flutriafol, epoxiconazole) shared ratio in composition;
A is metconazole.
B is a kind of in triazole bactericidal agent tetraconazole, Flusilazole, tricyclazole, Flutriafol, epoxiconazole;
Result of the test is as shown in the table:
Toxicity test result one
Table 1 tetraconazole, metconazole and the composite toxicity test analysis of results table to wheat rust thereof
As shown in Table 1, tetraconazole, the EC of metconazole to wheat rust
50be respectively 0.89mg/L and 1.12mg/L.Tetraconazole and metconazole were mixed in scope and all show obvious synergistic effect at 80: 1～1: 80.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and in 10: 1～1: 10 scope, mixed synergies is particularly outstanding.
Toxicity test result two
Table 2 tricyclazole, metconazole and the composite toxicity test analysis of results table to fruit white rot of grape thereof
As shown in Table 2, tricyclazole, the EC of metconazole to fruit white rot of grape
50be respectively 1.95mg/L and 1.14mg/L.Tricyclazole and metconazole were mixed in scope and all show obvious synergistic effect at 80: 1～1: 80.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and in 10: 1～1: 10 scope, mixed synergies is particularly outstanding.
Toxicity test result three
Table 3 Flutriafol, metconazole and the composite toxicity test analysis of results table to pear scab thereof
As shown in Table 3, Flutriafol, the EC of metconazole to pear scab
50be respectively 1.45mg/L and 1.21mg/L.Flutriafol and metconazole were mixed in scope and all show obvious synergistic effect at 80: 1～1: 80.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and in 10: 1～1: 10 scope, mixed synergies is particularly outstanding.
Toxicity test result four
Table 4 epoxiconazole, metconazole and the composite toxicity test analysis of results table to barley powdery mildew thereof
As shown in Table 4, epoxiconazole, the EC of metconazole to barley powdery mildew
50be respectively 1.39mg/L and 1.25mg/L.Epoxiconazole and metconazole were mixed in scope and all show obvious synergistic effect at 80: 1～1: 80.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and in 10: 1～1: 10 scope, mixed synergies is particularly outstanding.
Toxicity test result five
Table 5 Flusilazole, metconazole and the composite toxicity test analysis of results table to rice sheath blight disease thereof
As shown in Table 5, Flusilazole, the EC of metconazole to rice sheath blight disease
50be respectively 1.18mg/L and 1.12mg/L.Flusilazole and metconazole were mixed in scope and all show obvious synergistic effect at 80: 1～1: 80.Wherein, both mixed synergies in 20: 1～1: 20 scope are comparatively desirable, and in 10: 1～1: 10 scope, mixed synergies is particularly outstanding.
Implementation of an application example two: field control effectiveness test
Embodiment 1 60% Flusilazole metconazole wetting powder is prevented and treated the pear scab test of pesticide effectiveness
Flusilazole 50%, metconazole 10%, polycarboxylate 5%, sodium lignin sulfonate 3%, silkworm excrement 2%, diatomite add to 100%, and mixture carries out air-flow crushing, make 60% Flusilazole metconazole wetting powder.This proportioning is by 6000 times of dilution sprayings, and in their early stage dispenser, once, dispenser is 3 times altogether, within after last dispenser 7 days, 14 days, investigates respectively disease index and calculates preventive effect in dispenser in every 7 days.Within after medicine 7 days, 14 days, prevent and treat pear scab effect and be respectively 90.8%, 96.2%, 40% Flusilazole and 60g/L metconazole water and milk according to same method, by 7500 times and 600 times of dilution uses, after medicine, 14 days preventive effects are respectively 71.8% and 72.5% respectively.
In the present embodiment Flusilazole replaceable be a kind of in tetraconazole, tricyclazole, Flutriafol, epoxiconazole, thereby form new embodiment.
The embodiment 2 60% tricyclazole metconazole water dispersible granules control rice blast tests of pesticide effectiveness
Tricyclazole 40%, metconazole 20%, alkyl benzene sulfonate calcium salt 4%, sodium phosphate trimer 3%, wetting and penetrating agent F 3%, ammonium sulfate 1%, bentonite add to 100%, mix and make 60% tricyclazole metconazole water dispersible granules.This proportioning is by 15 grams/acre of dilution sprayings, and in their early stage dispenser, once, dispenser is 2 times altogether, within after last dispenser 7 days, 14 days, investigates respectively disease index and calculates preventive effect in dispenser in every 7 days.After medicine, 7 days, 14 days control rice blast effects are respectively 91.2%, 96.8%, 20% tricyclazole wettable powder and 60g/L metconazole water and milk are according to same method, by 80 grams/acre and 75 grams/acre of dilution uses, after medicine, 14 days preventive effects are respectively 72.8% and 71.2% respectively.
In the present embodiment tricyclazole replaceable be a kind of in tetraconazole, Flusilazole, Flutriafol, epoxiconazole, thereby form new embodiment.
Embodiment 3 48% epoxiconazole metconazole microemulsions are prevented and treated the sigatoka test of pesticide effectiveness
Epoxiconazole 40%, metconazole 8%, acetone 10%, agriculture breast 500# 8%, isobutanol 5%, hydroxyethylcellulose 2%, sodium sorbate 2%, silicone defoaming agent 0.5%, deionized water adds to 100%, mixes and makes 48% epoxiconazole metconazole microemulsion.This proportioning is by 3500 times of dilution sprayings, and in their early stage dispenser, once, dispenser is 3 times altogether, within after last dispenser 7 days, 14 days, investigates respectively disease index and calculates preventive effect in dispenser in every 7 days.Within after medicine 7 days, 14 days, prevent and treat sigatoka effect and be respectively 90.3%, 95.3%, 12.5% epoxiconazole suspension concentrate and 60g/L metconazole water and milk are according to same method, dilute respectively 1000 times and 600 times of uses, after medicine, 14 days preventive effects are respectively 66.3% and 73.4%.
In the present embodiment epoxiconazole replaceable be a kind of in tetraconazole, Flusilazole, tricyclazole, Flutriafol, thereby form new embodiment.
The embodiment 4 50% tetraconazole metconazole aqueous emulsion control powdery mildew of strawberry tests of pesticide effectiveness
Tetraconazole 10%, metconazole 40%, acetone 8%, alkylphenol polyoxyethylene phosphate 5%, polyvinyl alcohol 3%, alkyl benzene calcium sulfonate 5%, sodium chloride 2%, deionized water add to 100%, mix and make 50% tetraconazole metconazole aqueous emulsion.This proportioning is by 18 grams/acre of dilution sprayings, and in their early stage dispenser, once, dispenser is 2 times altogether, within after last dispenser 7 days, 14 days, investigates respectively disease index and calculates preventive effect in dispenser in every 7 days.After medicine, 7 days, 14 days control powdery mildew of strawberry effects are respectively 91.9%, 95.4%, 4% tetraconazole aqueous emulsion and 60g/L metconazole aqueous emulsion are according to same method, by 100 grams/acre and 75 grams/acre of dilution spraying uses, after medicine, 14 days preventive effects are respectively 69.3% and 71.5% respectively.
In the present embodiment tetraconazole replaceable be a kind of in epoxiconazole, Flusilazole, tricyclazole, Flutriafol, thereby form new embodiment.
Embodiment 5 30% Flutriafol metconazole suspending agents are prevented and treated the powdery mildew of cucumber test of pesticide effectiveness
Flutriafol 20%, metconazole 10%, polycarboxylate 4%, sodium lignin sulfonate 3%, DBSA 4%, silicone oil 0.2%, polyvinyl alcohol 1%, deionized water adds to 100%, mixes and makes 30% Flutriafol metconazole suspending agent.This proportioning is by 20 grams/acre of dilution sprayings, and in their early stage dispenser, once, dispenser is 2 times altogether, within after last dispenser 7 days, 14 days, investigates respectively disease index and calculates preventive effect in dispenser in every 7 days.Within after medicine 7 days, 14 days, prevent and treat powdery mildew of cucumber drug effect and be really respectively 91.9%, 96.5%, 12.5% Flutriafol missible oil and 60g/L metconazole water and milk are according to same method, by 65 grams/acre and 75 grams/acre of dilution spraying uses, after medicine, 14 days preventive effects are respectively 68.5% and 71.3% respectively.
In the present embodiment Flutriafol replaceable be a kind of in tetraconazole, Flusilazole, tricyclazole, epoxiconazole, thereby form new embodiment.
Embodiment 6 40% epoxiconazole metconazole suspension emulsions are prevented and treated the rice sheath blight disease test of pesticide effectiveness
Epoxiconazole 30%, metconazole 10%, polycarboxylate 3%, lignosulfonates 3%, neopelex 4%, polyoxyethylene nonylphenol ether modified phosphate 3%, acetone 6%, xanthans 0.5%, propane diols 3%, deionized water add to 100%, mix and make 40% epoxiconazole metconazole suspension emulsion.This proportioning is by 15 grams/acre of dilution sprayings, and in their early stage dispenser, once, dispenser is 2 times altogether, within after last dispenser 7 days, 14 days, investigates respectively disease index and calculates preventive effect in dispenser in every 7 days.Within after medicine 7 days, 14 days, prevent and treat rice sheath blight disease drug effect and be really respectively 91.7%, 95.8%, 125g/L epoxiconazole suspension concentrate and 60g/L metconazole water and milk are according to same method, by 60 grams/acre and 80 grams/acre of dilution uses, after medicine, 14 days preventive effects are respectively 72.8% and 73.5% respectively.
In the present embodiment epoxiconazole replaceable be a kind of in tetraconazole, tricyclazole, Flutriafol, Flusilazole, thereby form new embodiment.
Embodiment 7 10% tricyclazole metconazole seed treatments are processed wheat seed test
Tricyclazole 5%, metconazole 5%, polycarboxylate 4%, sodium lignin sulfonate 3%, dichlorophen 3%, salicylate 2%, alkyl benzene sulfonate calcium salt 3%, deionized water adds to 100%, mixes and makes 10% tricyclazole metconazole seed treatment.This proportioning is pressed 40g/100kg seed seed dressing, in closed container, seed dressing is mixed 1 minute with seed jolting, by planting seed to experimental field, and in one day laggard row man-made irrigation.After planting 28 days calculate preventive effect is 100%, does not observe and infects.Contrast medicament 28% tricyclazole suspension seed-coating agent and 10% metconazole seed dressing are used by same method, within after planting 28 days, calculate preventive effect and are respectively 86.9%, 87.2%.
In the present embodiment tricyclazole replaceable be a kind of in tetraconazole, Flusilazole, Flutriafol, epoxiconazole, thereby form new embodiment.
In above-described embodiment, the ratio of A, two kinds of active components of B can be adjusted within the scope of the synergy of 80: 1～1: 80, thereby forms new embodiment.
Claims (5)
1. a composition pesticide that contains metconazole, is characterized in that: in composition, the ratio of weight and number of active constituent A and B is 80:1～1:80, and described active constituent A is metconazole; Active constituent B is selected from a kind of in triazole bactericidal agent Flusilazole, tetraconazole, tricyclazole, Flutriafol, and composition pesticide is made wetting powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, seed treatment;
When making wetting powder, composition comprises following constituent content: active constituent A 1～80%, active constituent B1～80%, dispersant 5～10%, wetting agent 2～10%, filler 8～90%;
When making water dispersible granules, composition comprises following constituent content: active constituent A1～80%, active constituent B1～80%, dispersant 3～12%, wetting agent 1～8%, disintegrant 1～10%, binding agent 1～8%, filler 10～90%;
When making suspending agent, composition comprises following constituent content: active constituent A1～40%, active constituent B1～40%, dispersant 2～10%, wetting agent 2～10%, defoamer 0.1～1%, thickener 0.1～2%, antifreeze 0.1～8%, deionized water add to 100%;
When making aqueous emulsion, composition comprises following constituent content: active constituent A1～40%, active constituent B1～40%, solvent 1～30%, emulsifier 1～15%, co-emulsifier 0～8%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, deionized water are supplied surplus;
When making microemulsion, composition comprises following constituent content: active constituent A1～40%, active constituent B1～40%, solvent 1～30%, emulsifier 3～20%, co-emulsifier 0～12%, antifreeze 0～10%, thickener 0.1～2%, defoamer 0.01～2%, stabilizing agent 0～4%, and deionized water is supplied surplus;
Described dispersant is selected from one or more in alkylnaphthalene sulfonate, two (alkyl) naphthalenesulfonate formaldehyde condensation compound, naphthalene sulfonic acid-formaldehyde condensation product, aryl phenol polyoxyethylene succinate sulfonate, octylphenol polyethylene oxyethylene group ether sulfate, polycarboxylate, lignosulfonates, the phonetic formaldehyde condensation products sulphate of alkylphenol-polyethenoxy, alkyl benzene sulfonate calcium salt, naphthalene sulfonic acid-formaldehyde condensation product sodium salt, polyoxyethylene carboxylate;
Described wetting agent is selected from: one or more in lauryl sodium sulfate, neopelex, Nekal BX, wetting and penetrating agent F, spaonin powder, silkworm excrement, soapberry powder;
Described disintegrant is selected from: one or more in bentonite, urea, ammonium sulfate, glucose, aluminium chloride;
Described antifreeze is selected from: one or more in ethylene glycol, propane diols, glycerine, polyethylene glycol;
Described defoamer is selected from: C
8～10aliphatic alcohols, C
10～20one or more in saturated fat acids and acid amides, silicone oil, silicone compound;
Described emulsifier is selected from one or more in alkyl benzene sulfonate calcium salt, styrene polyoxyethylene ether ammonium sulfate salt, alkyl biphenyl ether disulfonic acid magnesium salts, triethanolamine salt, phenethyl phenol polyethenoxy ether, 600#, 700#, NP-10 phosphate, OP-10 phosphate, castor oil polyoxyethylene ether, sorbester p17, Tween 80,602#;
Described co-emulsifier is one or more in butanols, isobutanol, dodecanol-1, tetradecanol-1, octadecanol-1;
Described solvent is selected from one or more in toluene, dimethylbenzene, methyl alcohol, ethanol, acetone, ether, cyclohexanone, vegetable oil, dimethyl formamide, acetonitrile, polyethylene glycol, pyrrolidones, solvent N-chain alkyl pyrrolidones;
Described filler is selected from: one or more in kaolin, diatomite, bentonite, attapulgite, white carbon, starch, precipitated calcium carbonate.
2. a kind of composition pesticide that contains metconazole according to claim 1, is characterized in that: the ratio of weight and number of two kinds of active component A and B is 20:1～1:20.
3. a kind of composition pesticide that contains metconazole according to claim 2, is characterized in that: the ratio of weight and number of active component Flusilazole and metconazole is 10:1～1:10;
The ratio of weight and number of active component tetraconazole and metconazole is 10:1～1:10;
The ratio of weight and number of active component tricyclazole and metconazole is 10:1～1:10;
The ratio of weight and number of active component Flutriafol and metconazole is 10:1～1:10.
4. a kind of composition pesticide that contains metconazole according to claim 1, is characterized in that: in composition, the weight percentage of active component is gross weight 5%～85%.
5. a kind of composition pesticide that contains metconazole according to claim 4, is characterized in that: in composition, the weight percentage of active component is gross weight 10%～80%.
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| CN201010614877.1A CN102027987B (en) | 2010-12-30 | 2010-12-30 | Metconazole-containing pesticide composition |
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| CN103609567A (en) * | 2013-12-11 | 2014-03-05 | 北京燕化永乐生物科技股份有限公司 | Pesticide composition containing metconazole |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101019535A (en) * | 2007-02-14 | 2007-08-22 | 山东省烟台市农业科学研究院 | Germicide composition containing captan and possessing synergy |
| CN101588718A (en) * | 2006-12-15 | 2009-11-25 | 先正达有限公司 | Formulation |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5714507A (en) * | 1994-07-01 | 1998-02-03 | Janssen Pharmaceutica, N.V. | Synergistic compositions containing metconazole and another triazole |
| EP2168434A1 (en) * | 2008-08-02 | 2010-03-31 | Bayer CropScience AG | Use of azols to increase resistance of plants of parts of plants to abiotic stress |
| CN101790992A (en) * | 2010-04-16 | 2010-08-04 | 陕西美邦农药有限公司 | Disinsection composite containing clothianidin and phoxim |
| CN101790986B (en) * | 2010-04-16 | 2013-11-27 | 陕西美邦农药有限公司 | Fungicide composite containing tricyclazole and hexaconazole |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101588718A (en) * | 2006-12-15 | 2009-11-25 | 先正达有限公司 | Formulation |
| CN101019535A (en) * | 2007-02-14 | 2007-08-22 | 山东省烟台市农业科学研究院 | Germicide composition containing captan and possessing synergy |
Non-Patent Citations (2)
| Title |
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| 戊唑醇与羟菌唑对小麦赤霉病的防治效果及对小麦产量的影响;韩青梅等;《西北农林科技大学学报( 自然科学版)》;20050731;第33卷(第7期);第40－44页 * |
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Address after: 715500 Pucheng County of Shaanxi Province agricultural base industrial park Applicant after: Shaanxi Meibang Pesticide Co., Ltd. Address before: 710075, C, 15 floor, Jinqiao International Plaza, science and technology road, hi tech Zone, Shaanxi, Xi'an Applicant before: Shaanxi Meibang Pesticide Co., Ltd. |
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