CN102232548A - Cordyceps militaris-American ginseng capsule health-care product and preparation process thereof - Google Patents

Cordyceps militaris-American ginseng capsule health-care product and preparation process thereof Download PDF

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CN102232548A
CN102232548A CN2011102254155A CN201110225415A CN102232548A CN 102232548 A CN102232548 A CN 102232548A CN 2011102254155 A CN2011102254155 A CN 2011102254155A CN 201110225415 A CN201110225415 A CN 201110225415A CN 102232548 A CN102232548 A CN 102232548A
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cordyceps militaris
american ginseng
temperature
health
capsule
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朱旭伟
虞利东
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ZHEJIANG TIANSHI BIOENGINEERING CO Ltd
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Abstract

The invention discloses a cordyceps militaris-American ginseng capsule health-care product. The health-care product consists of the following materials in percentage by weight: 50 to 90 percent of cordyceps militaris sporocarp, and 10 to 50 percent of American ginseng. The invention also discloses a process for preparing the cordyceps militaris-American ginseng capsule health-care product. The process comprises the following steps of: 1, picking fresh cordyceps militaris sporocarp, and immediately drying and sterilizing by using microwave at low temperature, wherein the temperature is 30 to 80 DEG C; 2, cleaning the American ginseng, slicing, and drying and sterilizing by using microwave, wherein the temperature is 30 to 80 DEG C; and 3, crushing the two kinds of materials obtained in step 1 and step 2, screening with a sieve of 60 to 80 meshes, weighing the two kinds of crushed materials, namely 50 to 90 weight percent of cordyceps militaris sporocarp and 10 to 50 weight percent of American ginseng, adding purified water, mixing uniformly to obtain a soft material, drying at the temperature of between 60 and 80 DEG C, granulating, blending, and filling capsules, polishing and internally packaging to obtain cordyceps militaris-American ginseng capsules. The cordyceps militaris-American ginseng capsule health-care product has the effects of strengthening immunity and alleviating physical fatigue, is convenient to eat and carry, and is suitable to be eaten by people who have low immunity and physical fatigue.

Description

A kind of Cordyceps militaris American ginseng capsule health products and preparation technology thereof
Technical field
The invention belongs to technical field of health care products, be specifically related to a kind of Cordyceps militaris American ginseng capsule health products and preparation technology thereof that can strengthen immunity, alleviating physical fatigue.
Background technology
Health food is the healthy food of 21 century.In recent years, after problem of food and clothing was solved substantially, people's living standard improved constantly, and increasing people begins to pay close attention to the health problem of self.Health investment has become the consumption hot spot, and " spending money on health " becomes consumption fashion gradually.Simultaneously, owing to the reasons such as the continuous deterioration of natural environment that modern society's people's rhythm of life is accelerated day by day, operating pressure constantly increases, market competition is growing more intense, depend on for existence, cause in current society, so huge sub-health state crowd occurs: they often feel physical fatigue, spirit is not good enough, muscle power " overdraw ", this class community immunity hypofunction, easily catch a cold, naturally-aged quickens, be in the heart, cranial vascular disease or other chronic disease in earlier stage, but all do not reach the clinical disease diagnosis level to all indexs of examination in hospital.For this class crowd, can obviously improve body reason function by replenishing corresponding health food, thereby increase work efficiency and make the life better quality.Therefore, the present invention provides a kind of health food that can strengthen immunity, alleviating physical fatigue based on this.
Cordyceps militaris (Cordyceps militaris): have another name called northern Chinese caterpillar Fungus, the north Chinese caterpillar fungus, northeast Chinese caterpillar fungus etc., belong to Ascomycotina (Asco mycotina) gang pyrenomycetes (pyrenomycetes) Sphaerials (Sphaerinles) Clavicipitaceae (claviticpitaceae) Cordyceps (Coedyceps), it is the fungi that colonizes on the insect pupal cells such as Lepidoptera and coleoptera, it is one of China's rare traditional Chinese medicine, Cordyceps militaris is the type sepecies of Cordyceps, with Cordyceps sinensis be Cordyceps belong to the xenogenesis fungi together, both chemical compositions, nutritional labeling and medicinal function are all closely similar, its main medicinal ingredient cordycepin equal size is far above wild cordyceps, and be easier to artificial cultivation than Cordyceps sinensis, therefore be chosen as the best substitute of Cordyceps sinensis and carry out a large amount of artificial cultures." national Chinese herbal medicine compilation " record: fruiting bodies of cordyceps militaris also can be used as Cordyceps sinensis and is used as medicine.Similar by the Cordyceps militaris effect discovered in recent years to Cordyceps sinensis, regulating the immune system test shows, Cordyceps militaris has regulating action to cellular immunity and the humoral immunity of mouse, and can strengthen the phagocytic activity of peritoneal macrophage, in addition, can also significantly improve the lethality of NK and the content of serum hemolysin, the formation of enhancing antibody.Irritate stomach with the Cordyceps militaris extract and can obviously prolong the swimming time of mouse, have antifatigue effect.Wild cordyceps now has been in critically endangered state, is put into " national key protected wild plants register " second class protection kind, and price has surpassed gold, and the strict restriction collection of the Chinese government, sale, purchase wild Chinese caterpillar fungus are used for medicine, edible way.Therefore, adopt tame Cordyceps militaris (having another name called northern Chinese caterpillar fungus) product as an alternative, both can effectively protect the resources of natural crude drugs, can satisfy the growing edible and medicinal requirements in market again Chinese caterpillar fungus.2009, Ministry of Public Health's issue bulletin (2009 No. 3), the approval Cordyceps militaris is a new resource food.Functional component main in the Cordyceps militaris has: adenosine, cordycepin, SOD, Cordyceps sinensis polysaccharide, cordycepic acid etc.
American Ginseng: be American ginseng, American ginseng, U.S.'s genseng etc. again, the dry root of Araliaceae herbaceos perennial American Ginseng Panax quinque folium L..Originate in the U.S. and Canada, be famous and precious medicine, eat dual-purpose medicinal material, in China's clinical practice the earliest, the applicating history in existing more than 300 year." property of medicine is examined " states note, and " American ginseng steeps fourth like the white skin of the Liao Dynasty's ginseng, and flavor class genseng is only cold in nature, sweetness and bitterness; Tonifying yin is brought down a fever, and the useful unit of ginger system sets upright gas ".Go into the heart, lung, kidney channel, function is boosting qi and nourishing yin, clearing heat and promoting fluid.A large amount of development tests show that American Ginseng can obviously prolong the mouse swimming with a load attached to the body time, serum urea nitrogen level when reducing motion, and the consumption of minimizing hepatic glycogen, the content of minimizing motion back high dose group lactic acid reaches antifatigue effect; American Ginseng compares by high low dose group and model control group, and phagocytic index has significant difference P<0.05, and explanation can significantly improve the phagocytic function of mouse, thereby improves body's immunity.The efficacy of American ginseng composition is mainly: ginsenoside.
Fruiting bodies of cordyceps militaris miscellaneous in recent years, American ginseng product flood market, and as health food or food such as fruiting bodies of cordyceps militaris, American ginseng pill, American Ginseng sheets, take mode but mostly be the difference that single makes, and rare both compatibilities use; The health products that have are taken inconvenience, add mixing in water for oral taking as need, as spirituosity, certain crowd such as driver are had certain limitation; The health products that have adopt preparation methods such as high temperature extraction or high-temperature sterilization, the influence bigger to remaining with of active ingredient; The health products that have have added the numerous food additive, and what have exists excessive interpolation situation, even illegal interpolation medicine, and its Product Safety causes anxiety, and as Taiwan " plasticiser " incident, the security of adding food additives in food and health products causes anxiety; Simultaneously, the advertisement that has propagates " omnipotent " health care tonic to Cordyceps militaris, American Ginseng, misleads the consumption, and tends to cause harmful effect.
Summary of the invention
In order to overcome existing fruiting bodies of cordyceps militaris, the defective of American Ginseng Related product on production technology and function, the invention provides a kind of Cordyceps militaris American ginseng capsule health products and preparation technology thereof.
The present invention takes following technical scheme: a kind of Cordyceps militaris American ginseng capsule health products, be made up of by weight following material: fruiting bodies of cordyceps militaris accounts for 50%~90%, and American Ginseng accounts for 10%~50%.
The present invention also provides a kind of preparation technology of Cordyceps militaris American ginseng capsule health products:
One, fruiting bodies of cordyceps militaris is after bright product are plucked, to carry out the low-temperature microwave dry sterilization immediately and handle, and temperature is 30~80 ℃;
Two, after the clean system of American Ginseng, section is carried out microwave drying sterilization and is handled, and temperature is 30~80 ℃;
Three, two kinds of materials of step 1, step 2 are pulverized, and 60~80 orders that sieve; Account for 50%~90% by fruiting bodies of cordyceps militaris, American Ginseng accounts for 10%~50% part by weight and takes by weighing above-mentioned two kinds of comminuting matters, and the adding purified water mixes, makes softwood, dry down at 60~80 ℃, total the mixing in whole grain back, through capsule filling, polishing, inner packing, make the Cordyceps militaris American ginseng capsule.
Certainly, among the above-mentioned preparation technology, step 1 and step 2 can be exchanged or be carried out synchronously.
The purified water that Cordyceps militaris American ginseng capsule health products of the present invention are used, do not contain other any auxiliary material and food additives in Capsules and processing.
Cordyceps militaris American ginseng capsule health products of the present invention are compared with existing like product, and it has following technique effect:
The present invention shows through Zhejiang Center For Disease Control and Prevention of health food function test mechanism function test of Ministry of Public Health's appointment: have the dual-use function that strengthens immunity, alleviating physical fatigue, be applicable to hypoimmunity, fatigable crowd.Fruiting bodies of cordyceps militaris, American Ginseng raw material adopt the low-temperature microwave disinfecting and drying method to sterilize, and temperature is low, has reduced the loss of active ingredient, has improved the curative effect of final products; Can reach better health-care effect; After technologies such as pulverizing, system softwood, do not add any auxiliary material (except that purified water) and food additives, can fill with automatic capsule filling machine and make capsule, saved resource, help sustainable development of resource, do not contain other auxiliary material and food additives in the product, do not have the security risk of food additives, strengthened security of products.Select capsule formulation simultaneously, be convenient to take, carry, and have high bioavailability.
1, the present invention selects to have the fruiting bodies of cordyceps militaris that strengthens functions such as immunity and the American Ginseng with effects such as antifatigues as raw material, and both combinations have reached the synergy that has complementary functions, and has reached comprehensively, effective health-care effect.
2, the used fruiting bodies of cordyceps militaris raw material of the present invention adopts the aquatic foods product after plucking, and carries out microwave low temperature sterilization technology immediately and carries out drying, guarantees not losing of active ingredient.Compare with the back oven drying that dries of routine, its temperature is lower, the time is shorter, the active ingredient loss is littler.Table 1 pair microwave low-temperature drying sterilization of the present invention and conventional drying, conventional sterilization compare test: the contrast of table 1 microwave low-temperature drying sterilization process and other technologies
Figure BDA0000081741050000031
Data by last table are as can be known: microwave low-temperature drying sterilization of the present invention is equal to aspect the bactericidal effect with conventional 121 ℃ of hot air sterilizations, but active ingredient differs one times on keeping; Behind conventional 80 ℃ of dry sterilizations with the microwave low-temperature drying sterilization after active ingredient similar, but the effect that does not reach killing microorganisms.So product of the present invention adopted advanced microwave low-temperature drying sterilization process, have and keep Chinese caterpillar fungus, American Ginseng effect thermally labile component.Simultaneously, the present invention adopts the microwave low-temperature drying sterilization process to shorten drying time, can save energy consumption more than 50%.
3, compare with the products of selling in the market such as fruiting bodies of cordyceps militaris capsule, the present invention has adopted low-temperature microwave sterilization and low temperature drying processing technology, and the functional component loss is little, and reservation is many, the health care better effects if.As everyone knows, the quality of the processing technology of product directly has influence on the quality of product.As one of functional component of fruiting bodies of cordyceps militaris is adenosine, it is first health board fruiting bodies of cordyceps militaris capsule that name of product is arranged on the market, authentication code is the strong word G20050879 of state's food, the every 100g of its labeled marker contains: adenosine 15mg, in embodiments of the invention 1, only adenosine has just reached 161mg/100g, is more than 10 times of this product.With the comparisons such as American ginseng buccal tablet of sale in the market, enhancing immunity of the present invention, the physical-fatigue-relieving health effect is better.
4, the present invention does not add any auxiliary material (removing the purified water of using in Capsules and the technology) and food additives, wherein purified water is a kind of water for pharmaceutical purposes, do not contain any additives, be to be raw material with the drinking water, make by state-of-the-art in the world reverse osmosis technology (the genus state of the art) at present.So security of the present invention is higher, what the consumer can be relieved takes.
5, the present invention selects capsule formulation, and following characteristics are arranged: (1) capsule outward appearance is clean and tidy, attractive in appearance, is convenient to take, carry.(2) can cover bad flavor and the raising health food stability of smelling of healthy food material.Be isolated from the outside because of healthy food material is contained in the capsule shells, avoided the influence of moisture, air, light, bad flavor or the unsettled medicine smelt had covering to a certain extent, protection and stabilization.(3) bioavailability of medicament is higher.Medicine in the capsule is directly to load in softgel shell with powder or graininess, the influence of factor such as be not stressed, so dispersion rapidly, stripping and absorption in intestines and stomach, its bioavilability will be higher than pill, tablets and other formulations.(4) be fit to industrialized production.
Cordyceps militaris American ginseng capsule health products of the present invention have enhancing immunity through the evidence of national authority body function, and the alleviating physical fatigue effect is edible easy to carry, and suitable hypoimmunity, physical fatigue person eat.
The specific embodiment
Embodiment 1
Fruiting bodies of cordyceps militaris is after bright product are plucked, to carry out low-temperature microwave dry sterilization (60 ℃) immediately and handle.After the clean system of American Ginseng, section is carried out microwave drying sterilization (80 ℃) and is handled.With two kinds of raw material pulverizing, (80 order) sieves; Account for heavyly by 70% by fruiting bodies of cordyceps militaris (dry product), American Ginseng accounts for heavy 30% and takes by weighing above-mentioned two kinds of raw materials, specifically presses table 1 weighing, add an amount of purified water and mix, make softwood, low temperature drying (60 ℃), total the mixing in whole grain back, through capsule filling, polishing, inner packing, promptly get the Cordyceps militaris American ginseng capsule.
The prescription consumption of table 2 implementation column 1
The supplementary material title Quantity Ratio
Fruiting bodies of cordyceps militaris (dry product) 2.94kg 70%
American Ginseng 1.26kg 30%
Adenosine content is 161mg/100g after testing, and general ginsenoside content is 1410mg/100g, and microbiological indicator is qualified.
Embodiment 2
Fruiting bodies of cordyceps militaris is after bright product are plucked, to carry out low-temperature microwave dry sterilization (30 ℃) immediately and handle.After the clean system of American Ginseng, section is carried out microwave drying sterilization (30 ℃) and is handled.With two kinds of raw material pulverizing, (80 order) sieves; Account for heavyly by 60% by fruiting bodies of cordyceps militaris, American Ginseng accounts for heavy 40% and takes by weighing above-mentioned two kinds of raw materials, adds that purified water is mixed, the system softwood, low temperature drying (60 ℃), and total the mixing in whole grain back through capsule filling, polishing, inner packing, promptly gets the Cordyceps militaris American ginseng capsule.
The prescription consumption of table 3 implementation column 2
The supplementary material title Quantity Ratio
Fruiting bodies of cordyceps militaris (dry product) 3.00kg 60%
American Ginseng 2.00kg 40%
Adenosine content is 139mg/100g after testing, and general ginsenoside content is 1880mg/100g, and microbiological indicator is qualified.
The like product and the functional component content of listing see Table 4 at present, compare as can be known respectively at embodiment 1, embodiment 2, the product that the present invention adopts above-mentioned preparation technology to produce, the functional component adenosine content can reach more than 4 times of similar listing product, has embodied this product characteristics.
Table 4 like product and this product efficacy component content
Name of product Functional component content
Vigor board Cordyceps militaris capsule Adenosine: 38mg/100g
The glad board Cordyceps militaris of cloud silk astragalus capsules Adenosine: 19mg/100g
Elder generation's health board fruiting bodies of cordyceps militaris capsule Adenosine: 15mg/100g
This product (example 1 of the present invention) Adenosine: 161mg/100g
This product (example 2 of the present invention) Adenosine: 139mg/100g
Embodiment 3
Tame fruiting bodies of cordyceps militaris is after bright product are plucked, to carry out low-temperature microwave dry sterilization (70 ℃) immediately and handle.After the clean system of American Ginseng, section is carried out microwave drying sterilization (60 ℃) and is handled.With two kinds of raw material pulverizing, (60 order) sieves; Account for heavyly by 85% by fruiting bodies of cordyceps militaris (dry product), American Ginseng accounts for heavy 15% and takes by weighing above-mentioned two kinds of raw materials, adds that an amount of purified water is mixed, the system softwood, low temperature drying (80 ℃), total the mixing in whole grain back through capsule filling, polishing, inner packing, promptly gets the Cordyceps militaris American ginseng capsule.
The prescription consumption of table 5 implementation column 3
The supplementary material title Quantity Ratio
Fruiting bodies of cordyceps militaris (dry product) 4.25kg 85%
American Ginseng 0.75kg 15%
Adenosine content is 196mg/100g after testing, and general ginsenoside content is 705mg/100g, and microbiological indicator is qualified.
Embodiment 4
Fruiting bodies of cordyceps militaris is after bright product are plucked, to carry out low-temperature microwave dry sterilization (50 ℃) immediately and handle.After the clean system of American Ginseng, section is carried out microwave drying sterilization (40 ℃) and is handled.With two kinds of raw material pulverizing, (70 order) sieves; Account for heavyly by 55% by fruiting bodies of cordyceps militaris, American Ginseng accounts for heavy 45% and takes by weighing above-mentioned two kinds of raw materials, adds that purified water is mixed, the system softwood, low temperature drying (70 ℃), and total the mixing in whole grain back through capsule filling, polishing, inner packing, promptly gets the Cordyceps militaris American ginseng capsule.
The prescription consumption of table 6 implementation column 4
The supplementary material title Quantity Ratio
Fruiting bodies of cordyceps militaris (dry product) 2.75kg 55%
American Ginseng 2.25kg 45%
Adenosine content is 128mg/100g after testing, and general ginsenoside content is 2115mg/100g, and microbiological indicator is qualified.
Certainly, among above-mentioned 4 embodiment, the treatment step of the treatment step of fruiting bodies of cordyceps militaris and American Ginseng can be exchanged or carry out synchronously, also can reach technique effect of the present invention, no longer describe in detail.
Those of ordinary skill in the art will be appreciated that the present invention is not limited to the foregoing description, any conversion of the present invention, modification is all fallen into protection scope of the present invention.

Claims (4)

1. Cordyceps militaris American ginseng capsule health products, it is characterized in that by following material by weight forming: fruiting bodies of cordyceps militaris accounts for 50%~90%, and American Ginseng accounts for 10%~50%.
2. the preparation technology of Cordyceps militaris American ginseng capsule health products is characterized in that as follows:
One, fruiting bodies of cordyceps militaris is after bright product are plucked, to carry out the low-temperature microwave dry sterilization immediately and handle, and temperature is 30~80 ℃;
Two, after the clean system of American Ginseng, section is carried out microwave drying sterilization and is handled, and temperature is 30~80 ℃;
Three, two kinds of materials of step 1, step 2 are pulverized, and 60~80 orders that sieve; Account for 50%~90% by fruiting bodies of cordyceps militaris, American Ginseng accounts for 10%~50% part by weight and takes by weighing above-mentioned two kinds of comminuting matters, and the adding purified water mixes, makes softwood, dry down at 60~80 ℃, total the mixing in whole grain back, through capsule filling, polishing, inner packing, make the Cordyceps militaris American ginseng capsule.
3. the preparation technology of Cordyceps militaris American ginseng capsule health products as claimed in claim 2 is characterized in that: step 1 and step 2 are exchanged.
4. the preparation technology of Cordyceps militaris American ginseng capsule health products as claimed in claim 2 is characterized in that: step 1 and step 2 are carried out synchronously.
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102783638A (en) * 2012-07-20 2012-11-21 章操 Mixed powder of Cordyceps sinensis fungal powder and American ginseng, and its preparation method
CN102987405A (en) * 2012-10-17 2013-03-27 徐州鸿宇农业科技有限公司 Method for preparing health food capsules by using cordyceps militaris and cocoon extracts
CN103404871A (en) * 2013-07-01 2013-11-27 吉林省宏久生物科技股份有限公司 Red ginseng and cordyceps militaris beverage and preparation method thereof
CN104825511A (en) * 2015-01-14 2015-08-12 李永江 Traditional Chinese medicine new-technology formula
CN105361171A (en) * 2015-12-08 2016-03-02 天津中新药业集团股份有限公司第六中药厂 Composition with physical fatigue-relieving effect
CN106177014A (en) * 2016-08-26 2016-12-07 成都润馨堂药业有限公司 A kind of Cordyceps militaris (L.) Link. granule of enhancing immunity and preparation method thereof
CN107744531A (en) * 2017-10-16 2018-03-02 安徽大别山南岳金蝉花开发农民专业合作社 A kind of processing method spent based on microwave ultrasonic wave to golden cicada
CN109646463A (en) * 2018-07-04 2019-04-19 吉林省中晟制药有限公司 A kind of Cordyceps militaris capsules and preparation method thereof
CN113712202A (en) * 2020-05-08 2021-11-30 山东蓝康药业股份有限公司 Preparation method of ginseng-lithospermum with anti-fatigue effect
CN114963700A (en) * 2022-05-26 2022-08-30 四川默森药业有限公司 Dried silkworm chrysalis cordyceps sinensis and preparation process thereof

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102783638A (en) * 2012-07-20 2012-11-21 章操 Mixed powder of Cordyceps sinensis fungal powder and American ginseng, and its preparation method
CN102987405A (en) * 2012-10-17 2013-03-27 徐州鸿宇农业科技有限公司 Method for preparing health food capsules by using cordyceps militaris and cocoon extracts
CN102987405B (en) * 2012-10-17 2013-11-06 徐州鸿宇农业科技有限公司 Method for preparing health food capsules by using cordyceps militaris and cocoon extracts
CN103404871A (en) * 2013-07-01 2013-11-27 吉林省宏久生物科技股份有限公司 Red ginseng and cordyceps militaris beverage and preparation method thereof
CN104825511A (en) * 2015-01-14 2015-08-12 李永江 Traditional Chinese medicine new-technology formula
CN105361171A (en) * 2015-12-08 2016-03-02 天津中新药业集团股份有限公司第六中药厂 Composition with physical fatigue-relieving effect
CN105361171B (en) * 2015-12-08 2018-08-03 天津中新药业集团股份有限公司第六中药厂 One kind having composition for relieving physical fatigue
CN106177014A (en) * 2016-08-26 2016-12-07 成都润馨堂药业有限公司 A kind of Cordyceps militaris (L.) Link. granule of enhancing immunity and preparation method thereof
CN107744531A (en) * 2017-10-16 2018-03-02 安徽大别山南岳金蝉花开发农民专业合作社 A kind of processing method spent based on microwave ultrasonic wave to golden cicada
CN109646463A (en) * 2018-07-04 2019-04-19 吉林省中晟制药有限公司 A kind of Cordyceps militaris capsules and preparation method thereof
CN113712202A (en) * 2020-05-08 2021-11-30 山东蓝康药业股份有限公司 Preparation method of ginseng-lithospermum with anti-fatigue effect
CN114963700A (en) * 2022-05-26 2022-08-30 四川默森药业有限公司 Dried silkworm chrysalis cordyceps sinensis and preparation process thereof

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Application publication date: 20111109