CN102132766A - Application of potenline-containing licorice extract in preparing animal feed or drinking water - Google Patents
Application of potenline-containing licorice extract in preparing animal feed or drinking water Download PDFInfo
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- CN102132766A CN102132766A CN2011100542745A CN201110054274A CN102132766A CN 102132766 A CN102132766 A CN 102132766A CN 2011100542745 A CN2011100542745 A CN 2011100542745A CN 201110054274 A CN201110054274 A CN 201110054274A CN 102132766 A CN102132766 A CN 102132766A
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Abstract
The invention relates to an application of potenline-containing licorice extract in preparing an animal feed or drinking water. The feed or tonic is used for strengthening animal immunity and oxidization resistance.
Description
Technical field
The present invention relates to contain the purposes of licorice in making animal feed or drinking water tonic of glycyrrhizic acid.
Background technology
Piglet is very weak for the immunity of enteritis, so newborn piglet needs to obtain breast milk early, in addition, need regulate by food and improve its immune performance and non-oxidizability.Existing feed addictive main component is the antibiotics additive, and examples of such additives is used for a long time and had certain side effect, also may make animal produce the drug resistance and the residual property of medicine.Even have influence on human beings'health.For further improving growth in piglets speed, reduce the incidence of disease, reduce owing to the harm that antibiotic use brought, plant extracts becomes present nutrition scholar's research focus as additive.As everyone knows, contain many anti-oxidation active substances in the plant, but most just be proved external, this can only illustrate that polyphenoils can be used to protect feed to avoid oxidative damage; In addition, a powerful immune system is very important for keeping animal health.Nutriment that animal searches for food and composition thereof are by immune cell activated or change the immunocyte interaction and directly influence immune system, have thought now, have a kind of interaction between immunity and the nutrition.
The production performance of animal and its immune state are closely related.When body is in a good state of nutrition, body's immunological function also improves.The raising of the simultaneous body growth performance that immune system is improved, this may be to have strengthened the adaptive capacity of body to environmental stress because improve the immune system function for a long time, reduced stress level relatively, avoided immune system darker spread effect and movable the rolling up of immunity.Licorice provides body to participate in anti-oxidant and immune movable trophic factors.Participate in the anti-oxidant and immune response of excitating organism directly as nutrient substance on the one hand, on the other hand, participate in the activity of body Nutrition and Metabolism, promote the synthetic of nutriment.
The endogenic polyphenoils of body can be removed the polyradical of crossing of organism metabolism generation, common polyphenoils comprises VE, VC, beta carotene, the reduced glutathione (GSH) of non-enzyme etc., also has enzyme to comprise SOD, catalase (CAT) and GSH-Px etc.This test is added licorice and has been reduced activity in vivo oxygen vigor and mda content, activity and the TAC of GSH-Px, SOD have been improved, therefore, add licorice in the pig starter feed and may play the effect of safeguarding the normal oxidation resistance of body, to keeping normal physiological function of organism, it is significant to improve production performance.
Summary of the invention
An object of the present invention is to provide a kind of animal feed or drinking water tonic, the licorice that it contained has the animal immune of enhancing and antioxygenic property.
Another object of the present invention is to improve the animal palatability, improves feed intake, improves the speed of growth of animal.
According to the present invention, in making animal feed or drinking water tonic, realize by the licorice that contains glycyrrhizic acid that is used to strengthen animal immune and antioxygenic property that uses effective dose.Licorice preferably also contains glycyrrhizic acid, licoflavone is a kind of or its mixture.Preferred glycyrrhizic acid is a main component, and is no less than 50 dry weight %.Contain the glycyrrhizic acid of 1～90 dry weight %, the glycyrrhizic acid of 0.1～60 dry weight %, the licoflavone of 0.1～60 dry weight % in the extract, the total amount of these active components can change in very big limited field, but under the normal condition 1～700ppm, preferred 10-600ppm.Various active components all derive from natural plants.Animal feed and the drinking water tonic that contains active component of the present invention has significant effect to immunity and the antioxygenic property that strengthens animal.The existence of active component also can improve palatability and the feed intake of animal, improves the speed of growth.
The present invention relates to animal and desire used pre-composition and feed addictive in the preparation animal feed, this animal feed, pre-composition and feed addictive contain effective dose by glycyrrhizic acid, glycyrrhizic acid, licoflavone is a kind of or its mixture is formed, but does not have surface-active emulsifiers.
In the preferred embodiment of the present invention, animal feed can contain the licoflavone of 5-50ppm glycyrrhizic acid, 1-30ppm glycyrrhizic acid, 5-30ppm.In addition, animal feed preferably can also contain or not contain the chemical compound of other source plant.Active component is incorporated in the animal feed normally finishes by the pre-composition of preparation active component and other suitable additive.This pre-composition can contain other conventional additives of 2-10 dry weight % active mixture, 0-40 dry weight % and any conventional absorption carrier of 50-98 dry weight %.Carrier for example can contain that 40-50 dry weight % wood fibre, 8-10 dry weight % stearin, the curcuma powder of 4-5 dry weight %, 4-5 dry weight % lose face powder, 22-28 dry weight % lime stone, 1-3 dry weight % natural gum, for example gum arabic, 5-50 dry weight % sugar and/or starch and 5-15 dry weight % water.
Then, with this pre-composition and vitamin, enzyme, inorganic salts, capes thing, contain protein component, carbohydrate containing component, wheat time powder/or wheat bran mix, be prepared into the feed addictive that contains 0.5-5 dry weight % premix.Animal feed additive adds in the feed the most at last afterwards, and addition is to contain 1～700ppm in the feed, the active mixture of preferred 10-600ppm.Account for the 0.5-3 dry weight % of animal feed under the animal feed additive normal condition.Dry weight with feed is calculated, and animal feed of the present invention contains following composition usually:
A) 1-80%, preferred 10-70 dry weight % cereal,
B)-30%, preferred 1-15 dry weight % feed fat,
C)-85%, the non-cereal type of 10～50 dry weight % is outer contain the nutrient protein material and
D) 1～700ppm, preferred 10-600ppm mixture.A)-d) total amount is preferably at least 80 dry weight %.
When the preparation animal feed, animal feed additive can be mixed wheat, oat, barley, corn and rice that said dry ingredients is for example ground or pulverized by cereal with dry ingredients; With for example rape cake, soybean, cottonseed cake is the vegetable protein feed of base-material; The animal protein feed is fish meal, digested tankage, bone meal for example; Formed with for example blackstrap, milk powder and whey powder.After having mixed all additives of doing, can add the composition that becomes liquid after liquid component heats.Liquid component can be made up of lipid, and for example fat is as animal tallow and plant fat (can optionally liquefy by heating) and/or aliphatic acid.After mixing through geodetic, obtain the granular denseness of powdery, this depends on the degree that composition is pulverized.For preventing to separate, should preferably add water, the processing of the granulation that routinizes then, expansion or extrusion process to animal feed at storage period.Can remove any unnecessary water by drying.If desired, the granular animal feed of gained can also be milled to the smaller particles granularity.
Within the scope of the invention, can also produce the suspension of animal feed.If preparation is the feed of consumption immediately, will be especially easily.
The drinking water tonic can contain the licorice of 2-90 dry weight %, preferred 10-70 dry weight %.Preferred naturally contain glycyrrhizic acid, glycyrrhizic acid, licoflavone is a kind of or its mixture is formed, and preferred glycyrrhizic acid is the main component of mixture, first-selection is not less than 50 dry weight %.Contain the glycyrrhizic acid of 10～90 dry weight %, the glycyrrhizic acid of 0.1～60 dry weight %, the licoflavone of 0.1～60 dry weight % in the mixture.Wherein said amount is with the calculation of total of said component.Except that licorice, can also contain various other compositions of 10-98 dry weight % in the tonic.Composition commonly used is inorganic salts, vitamin, solubility or water dispersible property carrier.For example sugar, milk powder, whey powder and cellulose derivative and stabilizing agent such as water-soluble or water-dispersible polymers.When the preparation drinking water, be that tonic is added in the water under the normal condition, addition is to make the concentration of licorice become 1-700ppm, is preferably 10-200ppm.
Description of drawings
Fig. 1 is the preparation method of licorice.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is described in detail.
The biological experiment of 1 licorice
1 the preparation method with reference to the accompanying drawings of licorice obtains, and selects 20 of weanling pigs under the identical condition of feeding for use, is divided into 2 groups at random, and the common daily ration of feeding respectively adds 2% licorice, feeds 60 days.
Adopt corn flour-dregs of beans type daily ration, it is as follows specifically to fill a prescription:
Test group and control group are all fed under same animal house condition except that daily ration is different, freely drink water.Feed intake, body weight, haematogenic immunity index, the anti-oxidant indicator-specific statistics result of blood are as table 1-3.
(1) with respect to control group, experimental group can improve average feed intake and the daily gain of piglet.
Table 1 adds the influence of licorice to piglet feed intake and daily gain
(2) with respect to control group, licorice has improved the immune performance of piglet.
Become metabolism, improve body's immunity, thereby improve the body health degree.Licorice is added in this test significantly raises serum IgA, the trend that IgG is had increase; The ratio of rising of body T lymphocyte subsets CD4+ ratio and CD4+/CD8+ is improved.Illustrate that licorice can improve the humoral immunity and the cellular immune level of body.
Table 2 adds the influence of licorice to the piglet blood immune indexes
Table 3 adds the influence of licorice to the piglet oxidation resistance
2, the biological experiment of glycyrrhizic acid
The licorice process is further purified the acquisition glycyrrhizic acid, and detects its activity by experiment, and control group adopts corn flour-dregs of beans type daily ration, and experimental group is identical with the control group daily ration, but additionally adds the 600ppm glycyrrhizic acid.
1.4.1 piglet biochemical indicator testing result is shown in table 4-6, with respect to control group, glycyrrhizic acid has improved the immune performance of piglet.
Table 4 glycyrrhizic acid strengthens immunization
| Group | The PHA cell changes | Leukocytes phagocytic | The E-rosette rate | The C3b receptor garland | Red blood cell IC flower |
| The change rate | Ability | Rate | The ring rate | ||
| Control group | 50.11 | 24.67 | 42.01 | 8.23 | 6.78 |
| Test group | 59.03 | 30.12 | 45.47 | 9.76 | 5.48 |
Table 5 glycyrrhizic acid strengthens immunization
Table 6 glycyrrhizic acid strengthens immunization
Should be understood that, for those of ordinary skills, can be improved according to the above description or conversion, and all these improvement and conversion all should belong to the protection domain of claims of the present invention.
Claims (9)
1. contain the purposes of licorice in preparation animal feed or drinking water tonic of glycyrrhizic acid, said feed or tonic can be used for improving immune performance and/or the antioxygenic property of animal, the optional active component that contains or do not contain other plant extract.
2. the described purposes of claim 1, described licorice also contains glycyrrhizic acid, licoflavone or its mixture.
3. purposes according to claim 1, described licorice are that alcohol or water are carried and being obtained.
4. according to any described purposes of claim 1-3, wherein said animal is a pig.
5. any described purposes of claim 1-3 wherein contains the glycyrrhizic acid of 1～90 dry weight %, the glycyrrhizic acid of 0.1～60 dry weight %, the licoflavone of 0.1～60 dry weight % in the liquorice beverage extract.
6. feed that improves animal immune performance and/or antioxygenic property, wherein animal feed contains:
A) 10～70 dry weight % cereal,
B) 1～15 dry weight % feed fat,
C) the non-cereal type of 10～50 dry weight % is outer contain the nutrient protein material and
D) 1～700ppm contains the licorice of glycyrrhizic acid.
The optional active component that contains or do not contain other plant extract.
7. animal feed as claimed in claim 6, it is characterized in that calculating with the dry weight of animal feed, the licorice that contains 10～200ppm optionally in the said extract contains in glycyrrhizic acid, the licoflavone one or both, and does not contain any surface-active emulsifiers.
8. the animal feed of claim 7 is characterized in that mixture by being made up of the glycyrrhizic acid of 1～90 dry weight %, the glycyrrhizic acid of 0.1～60 dry weight %, the licoflavone of 0.1～60 dry weight %, and said quantity is with the calculation of total of said component.
9. drinking water that improves animal immune performance and/or antioxygenic property, it is characterized in that containing in the drinking water 1～700ppm and contain the licorice of glycyrrhizic acid and vitamin, amino acid, enzyme preparation, inorganic salts, soluble carrier as sugar, milk powder, milk byproduct and cellulose derivative and/or stabilizing agent, the optional active component that contains or do not contain other plant extract.
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Cited By (8)
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| CN103636948A (en) * | 2013-12-26 | 2014-03-19 | 重庆市优胜科技发展有限公司 | Liquorice extract feed additive |
| WO2014143116A1 (en) * | 2012-04-24 | 2014-09-18 | Purina Animal Nutrition Llc | Feeding methods and systems for young livestock animals using sensory compounds |
| CN107811119A (en) * | 2017-10-31 | 2018-03-20 | 广州骊加生物科技有限公司 | A kind of application of radix glycyrrhizae acid metal complex in animal feed additive |
| CN109619035A (en) * | 2019-01-15 | 2019-04-16 | 重庆美健达农业开发有限公司 | A kind of feeding method promoting live pig meat using herb extracts |
| CN111184132A (en) * | 2020-01-17 | 2020-05-22 | 李仁� | Method for extracting, preparing and using licorice flavonoids as feed additive |
| US10940172B2 (en) | 2017-01-03 | 2021-03-09 | Purina Animal Nutrition Llc | Methods of feeding animals phytogenic products |
| US11213051B2 (en) | 2014-07-02 | 2022-01-04 | Purina Animal Nutrition Llc | Milk replacer products containing halides and sources of hydrogen peroxide and methods of feeding same |
| CN115462464A (en) * | 2022-09-28 | 2022-12-13 | 湖南佛斯特萌宠科技股份有限公司 | Feed additive and functional feed for dog or cat dermatosis rehabilitation nutritional nursing and application thereof |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014143116A1 (en) * | 2012-04-24 | 2014-09-18 | Purina Animal Nutrition Llc | Feeding methods and systems for young livestock animals using sensory compounds |
| US9668500B2 (en) | 2012-04-24 | 2017-06-06 | Purina Animal Nutrition Llc | Feeding methods and systems for young livestock animals using sensory compounds |
| US11291220B2 (en) | 2012-04-24 | 2022-04-05 | Purina Animal Nutrition Llc | Feeding methods and systems for young livestock animals using sensory compounds |
| CN103636948A (en) * | 2013-12-26 | 2014-03-19 | 重庆市优胜科技发展有限公司 | Liquorice extract feed additive |
| US11213051B2 (en) | 2014-07-02 | 2022-01-04 | Purina Animal Nutrition Llc | Milk replacer products containing halides and sources of hydrogen peroxide and methods of feeding same |
| US10940172B2 (en) | 2017-01-03 | 2021-03-09 | Purina Animal Nutrition Llc | Methods of feeding animals phytogenic products |
| US11883451B2 (en) | 2017-01-03 | 2024-01-30 | Purina Animal Nutrition Llc | Methods of feeding animals phytogenic products |
| CN107811119A (en) * | 2017-10-31 | 2018-03-20 | 广州骊加生物科技有限公司 | A kind of application of radix glycyrrhizae acid metal complex in animal feed additive |
| CN109619035A (en) * | 2019-01-15 | 2019-04-16 | 重庆美健达农业开发有限公司 | A kind of feeding method promoting live pig meat using herb extracts |
| CN111184132A (en) * | 2020-01-17 | 2020-05-22 | 李仁� | Method for extracting, preparing and using licorice flavonoids as feed additive |
| CN115462464A (en) * | 2022-09-28 | 2022-12-13 | 湖南佛斯特萌宠科技股份有限公司 | Feed additive and functional feed for dog or cat dermatosis rehabilitation nutritional nursing and application thereof |
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