CN101804167B - Chinese drug for calming endopathic wind and reducing blood pressure and preparation method thereof - Google Patents

Chinese drug for calming endopathic wind and reducing blood pressure and preparation method thereof Download PDF

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CN101804167B
CN101804167B CN2010101788907A CN201010178890A CN101804167B CN 101804167 B CN101804167 B CN 101804167B CN 2010101788907 A CN2010101788907 A CN 2010101788907A CN 201010178890 A CN201010178890 A CN 201010178890A CN 101804167 B CN101804167 B CN 101804167B
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radix
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杨贞利
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Abstract

The invention relates to a Chinese drug for calming endopathic wind and reducing blood pressure and a preparation method thereof. The Chinese drug is used for treating hypertension, encephalemia, hemiparalysis, limb and trunk paralysis, slurred speech or facial hemiparalysis, and is prepared as pills with cinnamon, achyranthes root, prepared rehmannia root, fructus toosendan, tortoise plastron, selfheal spike, capillary artemisia, white peony root, radix scrophulariae, asparagus root, malt, liquorice, oyster, leech 5, fossil teeth, skunk bush, goldthread root, medcinal evodia fruit, white atractylodes rhizome, uncaria, tuckahoe, gastrodia elata, ruddle, cortex eucommiae and parasitic loranthus. When being taken, the Chinese drug is boiled for 35-40 minutes in clean water, and the supernatant is used for preparing soup; or the Chinese drug is boiled for 5-10 minutes in clean water, dried and ground to powder, mixed in a tile basin, and stirred thoroughly and made into pills or capsules. The weight of each pill is about 6g, and the weight of each capsule is about 1g. The Chinese drug has the function of treating the hypertension, encephalemia, hemiparalysis, limb and trunk paralysis, slurred speech and facial hemiparalysis. The preparation method has the advantages of low manufacturing cost, simple process, fast absorption, high cure rate, less recurrence and no toxic side effect.

Description

A kind of Chinese hypotensor and preparation method thereof that relieves dizziness, high fever, infantile convulsions, epilepsy, etc.
Technical field
The present invention relates to a kind of Chinese medicine,, belong to medicine and medicine manufacture field in particular for treatment hypertension, cerebral hemorrhage, hemiplegia, quadriplegia, slurred speech, facial hemiparalysis etc.
Background technology
Hypertension is the modal cardiovascular disease in the world, also is one of maximum epidemic diseases, often causes the complication of internal organs such as the heart, brain, kidney, and human beings'health in serious harm.Its cause of disease is multifactor, and now many tendencies think that primary disease is genetic predisposition and environmental factors results of interaction, and the clinical manifestation of primary disease is many based on headache, dizzy, dizzy, cardiopalmus, insomnia, uncomfortable in chest, irritated and easy tired etc.Its pathogenesis is mainly the hepatic and renal YIN deficiency, excessive rising of liver-YANG, and it is also arranged in view of Sheng and deficiency of both YIN and YANG, upward floating of YANG in deficiency condition person in congestion internal resistance, the phlegm-damp.
The medicament categories of existing treatment high blood pressure disease is various, as publication number is that the patent application of CN1269238A discloses a kind of compound hypertension medicine, adopt the bonded mode in Chinese and Western, it is rapid to have blood pressure lowering, the advantage of taking convenience, but Western medicine has side effect to human body, and take the dependence that can cause for a long time to medicine, can only take stopgap measures, can not effect a permanent cure.Publication number is that the patent application of CN1660217 discloses a kind of Chinese patent medicine, and this medication effect is remarkable, and is with low cost, and is nontoxic, have no side effect, but its manufacturing process complexity.
Summary of the invention
The present invention is based on the shortcoming of said medicine, the Chinese medicine of a kind of treatment hypertension, cerebral hemorrhage, hemiplegia, quadriplegia, slurred speech, facial hemiparalysis has been proposed, its cost of manufacture is low, technology is simple, rapid-action, cure rate is high, be difficult for recurrence, and diseases such as treatment hypertensive cerebral hemorrhage are had significant curative effect.
Chinese Traditional Medicines provided by the invention are pills of being made by following proportion raw material medicine combination, are expressed as by weight:
Cortex Cinnamomi 1-3 weight portion, Radix Achyranthis Bidentatae 8-12 weight portion, Radix Rehmanniae Preparata 1-3 weight portion, a river 2-4 weight portion,
Carapax et Plastrum Testudinis 3-5 weight portion, Spica Prunellae 2-4 weight portion, Herba Artemisiae Scopariae 4-6 weight portion, Radix Paeoniae Alba 3-5 weight portion,
Radix Scrophulariae 3-5 weight portion, Radix Asparagi 3-5 weight portion, Fructus Hordei Germinatus 3-5 weight portion, Radix Glycyrrhizae 3-5 weight portion,
Concha Ostreae 4-6 weight portion, Hirudo 4-6 weight portion, Dens Draconis 4-6 weight portion, Fructus Corni 3-5 weight portion,
Rhizoma Coptidis 3-5 weight portion, Fructus Evodiae 1-2 weight portion, Rhizoma Atractylodis Macrocephalae 1-3 weight portion, Ramulus Uncariae Cum Uncis 3-5 weight portion,
Poria 3-5 weight portion, Rhizoma Gastrodiae 3-5 weight portion, Haematitum 8-12 weight portion, Cortex Eucommiae 8-11 weight portion,
Herba Taxilli 8-11 weight portion
The optimal proportion that each Chinese medicine is formed in this programme is:
Cortex Cinnamomi 2 weight portions, Radix Achyranthis Bidentatae 10 weight portions, Radix Rehmanniae Preparata 2 weight portions, river 3 weight portion,
Carapax et Plastrum Testudinis 4 weight portions, Spica Prunellae 3 weight portions, Herba Artemisiae Scopariae 5 weight portions, the Radix Paeoniae Alba 4 weight portions,
Radix Scrophulariae 4 weight portions, Radix Asparagi 4 weight portions, Fructus Hordei Germinatus 4 weight portions, Radix Glycyrrhizae 4 weight portions,
Concha Ostreae 5 weight portions, Hirudo 5 weight portions, Dens Draconis 5 weight portions, Fructus Corni 4 weight portions,
Rhizoma Coptidis 4 weight portions, Fructus Evodiae 1 weight portion, the Rhizoma Atractylodis Macrocephalae 2 weight portions, Ramulus Uncariae Cum Uncis 4 weight portions,
Poria 4 weight portions, Rhizoma Gastrodiae 4 weight portions, Haematitum 10 weight portions, the Cortex Eucommiae 10 weight portions,
Herba Taxilli 10 weight portions
Its preparation method is, this pharmaceutical composition was put in the clear water steaming and decocting 35-40 minute, gets supernatant and make decoction, perhaps be put in the clear water after the sterilization in steaming and decocting 5-10 minute, take out and dry grind into fine powder, put into and make pill or capsule after earthen basin mixes, stirs.Heavily about 6 grams of every ball, each heavily about 1 gram of capsule.
Hypertension is not to be to be caused by single factors, but the result of multiple factor interaction.The traditional Chinese medical science thinks that hypertension is to be caused a disease by factors such as wind, fire, expectorant, void, the stasis of bloods, and sick position is at liver, kidney, the heart, spleen, and the cause of disease is feelings will internal injury, depression of liver-QI, the hepatic and renal YIN deficiency, excessive rising of liver-YANG, fire-transformation wind-transformation; Or because of eating and drinking without temperance, give birth in expectorant is turbid and disturb key and worn with age clearly, imbalance of YIN and YANG, QI and blood deficiency checks blood vessels, causes congestion resistance network.It is relevant that the heart that hypertension causes, brain, kidney target organ damage and nature unusual weather conditions, the stimulation of feelings will, improper diet and overtiredness or phlegm retention congestion destroy human body relative balance state associated diseases.When six climate exopathogens seven emotions, phlegm retention congestion, when improper diet and overtiredness is caused a disease, upset the human body negative and positive from steady regulating action, cause QI and blood disorderly contrary, function is unbalance.The disease model of Chinese medicine is the change of the deficiency and excess of " institute of heresy gathers, and its gas must be empty ".Must catch whole this important step of medical treatment.
Hypertension is the disease of deficiency in origin and excess in superficiality, and its pathological changes internal organs are attached most importance to liver, spleen, the heart, kidney, and again based on liver, the vital organs of the human body are an integral body, and often influence each other transforms mutually, can not make this genus of sun deficiency of YIN as deficiency of kidney-essence, can transfer the disease of deficiency in both YIN and YANG to; Stagnation of phlegm-damp in middle-JIAO is contained partially from the beginning of many damp-phlegm, but stagnation of phlegm converting into fire with the passing of time forms phlegm-fire for suffering from.Therefore need detailed survey carefully to distinguish, anxious person is how real partially, can select for use relieve dizziness, high fever, infantile convulsions, epilepsy, etc., YANG hyperactivity suppressing, relieve inflammation or internal heat, suppressing the hyperactive liver, reduce phlegm, invigorate blood circulation, ruling by law such as collateral dredging its be designated as the master, how partially slow person void, when with methods such as QI and blood regulating, kidney tonifying, nourishing the liver, easing the affected liver, spleen invigorating to effect a permanent cure.
Ramulus Uncariae Cum Uncis among the we, the cool liver of Radix Asparagi heat clearing away, relieving spasm by subduing liver-wind are we's principal agent, and Rhizoma Gastrodiae, Spica Prunellae, river, Radix Scrophulariae, Herba Artemisiae Scopariae are accessory drugs, and auxiliary principal agent liver heat removing relieves dizziness, high fever, infantile convulsions, epilepsy, etc., makes eye bright, and ends headache; Fire and wind stirring up each other, the easiest consumption impairment of YIN liquid, so with Cortex Cinnamomi, the Radix Paeoniae Alba, Radix Glycyrrhizae YIN supplementing and fluids increasing with easing the affected liver blood; The prolonged illness deficiency of kidney yin can not be made sun, causes flaming up of liver-fire prosperous partially, thus with Carapax et Plastrum Testudinis, Fructus Hordei Germinatus, Fructus Corni,, Poria, Herba Taxilli grow the water kidney tonifying; Disturbing upward of liver-fire is held wind-phlegm again under the arm, it is descending to ignite, relieving dizziness, high fever, infantile convulsions, epilepsy, etc. reduces phlegm ends dizzy effect so reach with Radix Achyranthis Bidentatae, Fructus Evodiae, Concha Ostreae, Haematitum, Spica Prunellae, Fructus Hordei Germinatus, Hirudo, Fructus Corni, Rhizoma Coptidis, Fructus Evodiae, Ramulus Uncariae Cum Uncis, Radix Achyranthis Bidentatae, the Cortex Eucommiae etc., all have to bring high blood pressure down preferably and the effect of blood fat reducing, Radix Glycyrrhizae has the coordinating the actions of various ingredients in a prescription effect again in addition.Therefore symptoms such as the hypertension that a variety of causes is caused, cerebral hemorrhage, hemiplegia, quadriplegia, slurred speech, facial hemiparalysis all have good curative effect.
Clinical test results is after 300 routine patients take this medicine, and cure rate is 87.6%, and effective percentage is 95%, is a kind of cure rate height, the efficient oral medicine that has no side effect.
Model case:
1. Zhang, man, 44 years old, first visit on October 14 in 2005
The main suit: headache ophthalmic bloated 2 years is surplus, swells to the measuring blood pressure 200/120mmHg of hospital because of eyes at that time, has the soreness of waist, edema of lower limbs, urine foam many during one's sickness.No family history of hypertension.
Check result: blood pressure 210/140mmHg, heart rate 96 times/minute, rule is neat, routine urinalysis albumen +++, erythrocyte 0~2/H, creatinine 224.3umol/L, two kidneys and adrenal gland's B ultrasonic no abnormality seen.
Dialectical: the headache ophthalmic bloated is an excessive rising of liver-YANG, heat-transformation impairment of YIN, hyperactivity of YANG due to deficiency of YIN, due to disturbing on the wind-phlegm, original kidney is impaired, the prolonged illness hepatic and renal YIN deficiency, internal organs are not normal, thus the time face, edema of lower limbs arranged, the soreness of waist, urine show bubble, stringy and rolling pulse is that liver-wind is held wind under the arm, the gesture of disturbing on the expectorant, card belongs to excess of liver-YANG, liver-wind stirring up internally, kidney yin is deficient, the kidney failing to nourish the liver.
The clothes we, every day 2 times, sooner or later respectively once, after continuous 14 days, headache ophthalmic bloated symptom sees all and alleviates that blood pressure is reduced to 160/100mmHg, urine examination: urine protein (±), occult blood (+~++), blood urea nitrogen 9.1mmol/L, creatinine 142.7umol/L, continued to take this medicine 3 months, as a means of consolidation, renal function takes a turn for the better so far to some extent, and various functional rehabilitations are normal.
2. Liu, woman, 62 years old, December in 2005 first visit on the 24th.
The main suit: uncomfortable 3 months of distending pain in the head (with the crown for very), vertigo, ophthalmic bloated, facial paroxysm is warmed, dysphoria with feverish sensation in the chest palms and soles, irritated irritability, constipation with dry stool.No family history of hypertension.
Check result: blood pressure: 170/100mmHg
Clothes we, every day 2 times, sooner or later each once, two days later, distending pain in the head obviously alleviates, free movement of the bowels, dimly red tongue, stringy and thready pulse, blood pressure 156/96mmHg continues to take this medicine January, distending pain in the head is not sent out, blood pressure and every function are all in normal range.
3. Zhao, woman, 50 years old, first visit on January 3 in 2006.
Concise and to the point medical history: 2004 because of inarticulateness, slobbering, left hemiplegia, dull expression, bradykinesia, blood pressure 160/96mmHg.Family history of hypertension.
Check result: cerebral infarction, take medicine and do not feel any better, can only keep.
The clothes we are cancellation support medicine after one month, continues to take bad sensation complete obiteration after 3 months, and various inspections are all normal, and are healthy so far.
The specific embodiment
Embodiment 1
Get this medicine Cortex Cinnamomi 2g, Radix Achyranthis Bidentatae 10g, Radix Rehmanniae Preparata 2g, a river 3g, Carapax et Plastrum Testudinis 4g, Spica Prunellae 3g, Herba Artemisiae Scopariae 5g, Radix Paeoniae Alba 4g, Radix Scrophulariae 4g, Radix Asparagi 4g, Fructus Hordei Germinatus 4g, Radix Glycyrrhizae 4g, Concha Ostreae 5g, Hirudo 5g, Dens Draconis 5g, Fructus Corni 4g, Rhizoma Coptidis 4g, Fructus Evodiae 1g, Rhizoma Atractylodis Macrocephalae 2g, Ramulus Uncariae Cum Uncis g, Poria 4g, Rhizoma Gastrodiae 4g, Haematitum 10g, Cortex Eucommiae 10g, Herba Taxilli 10g.During use, get Chinese medicinal components and be put in the clear water after steaming and decocting 5-10 minute, take out and dry grind into fine powder, put into and make pill after earthen basin mixes, stirs, heavily about 6 grams of every ball, service once every day sooner or later.

Claims (9)

1. Chinese hypotensor that relieves dizziness, high fever, infantile convulsions, epilepsy, etc. is characterized in that the crude drug of this Chinese medicine consists of:
Cortex Cinnamomi 1-3 weight portion, Radix Achyranthis Bidentatae 8-12 weight portion, Radix Rehmanniae Preparata 1-3 weight portion, a river 2-4 weight portion, Carapax et Plastrum Testudinis 3-5 weight portion, Spica Prunellae 2-4 weight portion, Herba Artemisiae Scopariae 4-6 weight portion, Radix Paeoniae Alba 3-5 weight portion, Radix Scrophulariae 3-5 weight portion, Radix Asparagi 3-5 weight portion, Fructus Hordei Germinatus 3-5 weight portion, Radix Glycyrrhizae 3-5 weight portion, Concha Ostreae 4-6 weight portion, Hirudo 4-6 weight portion, Dens Draconis 4-6 weight portion, Fructus Corni 3-5 weight portion, Rhizoma Coptidis 3-5 weight portion, Fructus Evodiae 1-2 weight portion, Rhizoma Atractylodis Macrocephalae 1-3 weight portion, Ramulus Uncariae Cum Uncis 3-5 weight portion, Poria 3-5 weight portion, Rhizoma Gastrodiae 3-5 weight portion, Haematitum 8-12 weight portion, Cortex Eucommiae 8-11 weight portion, Herba Taxilli 8-11 weight portion
2. Chinese medicine as claimed in claim 1 is characterized in that, this Chinese medicine weight proportion is:
Cortex Cinnamomi 2 weight portions, Radix Achyranthis Bidentatae 10 weight portions, Radix Rehmanniae Preparata 2 weight portions, river 3 weight portion, Carapax et Plastrum Testudinis 4 weight portions, Spica Prunellae 3 weight portions, Herba Artemisiae Scopariae 5 weight portions, the Radix Paeoniae Alba 4 weight portions, Radix Scrophulariae 4 weight portions, Radix Asparagi 4 weight portions, Fructus Hordei Germinatus 4 weight portions, Radix Glycyrrhizae 4 weight portions, Concha Ostreae 5 weight portions, Hirudo 5 weight portions, Dens Draconis 5 weight portions, Fructus Corni 4 weight portions, Rhizoma Coptidis 4 weight portions, Fructus Evodiae 1 weight portion, the Rhizoma Atractylodis Macrocephalae 2 weight portions, Ramulus Uncariae Cum Uncis 4 weight portions, Poria 4 weight portions, Rhizoma Gastrodiae 4 weight portions, Haematitum 10 weight portions, the Cortex Eucommiae 10 weight portions, Herba Taxilli 10 weight portions.
3. Chinese medicine as claimed in claim 1 or 2 is characterized in that, is used for the treatment of hypertension.
4. Chinese medicine as claimed in claim 3 is characterized in that, this Chinese medicine is made any medicament in decoction, capsule and the pill.
5. as preparation method of Chinese medicine as described in the claim 3, it is characterized in that, get the component of described Chinese medicine by weight, be put in and boil 35-40 minute in the clear water, get supernatant and make decoction.
6. as preparation method of Chinese medicine as described in the claim 4, it is characterized in that, get the component of described Chinese medicine by weight, be put in boil sterilization in 5-10 minute in the clear water after, take out and dry grind into fine powder, put into and make pill after earthen basin mixes, stirs.
7. as preparation method of Chinese medicine as described in the claim 6, it is characterized in that the every ball of described pill weighs 6 grams.
8. as preparation method of Chinese medicine as described in the claim 4, it is characterized in that, get the component of described Chinese medicine by weight, be put in boil sterilization in 5-10 minute in the clear water after, take out and dry grind into fine powder, put into and make capsule after earthen basin mixes, stirs.
9. preparation method as claimed in claim 8 is characterized in that, each heavy 1 gram of described capsule.
CN2010101788907A 2010-05-21 2010-05-21 Chinese drug for calming endopathic wind and reducing blood pressure and preparation method thereof Expired - Fee Related CN101804167B (en)

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Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103169797B (en) * 2011-12-23 2014-04-02 天津市乐草堂生物科技开发有限公司 Traditional Chinese medicine hypotensive paste
CN103239539B (en) * 2013-05-30 2014-08-06 陈洪凯 Compound medicine for external use for treating hypertension and application thereof
CN104257803A (en) * 2014-09-16 2015-01-07 四川圣湖生物科技有限公司 Pharmaceutical composition for treating snore as well as preparation method and application of pharmaceutical composition
CN104922440A (en) * 2015-06-05 2015-09-23 李跃 Anti-hypertension lavipeditum foot-soaking traditional Chinese medicine for treating heart-kidney imbalance type hypertension
CN106344694A (en) * 2016-10-26 2017-01-25 杨保荣 Medicine for treating hypertension and hyperlipidemia and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1092666A (en) * 1993-03-19 1994-09-28 杨诗琴 A kind of hypotensive palsy-treating preparation and preparation method thereof
CN1546118A (en) * 2003-12-10 2004-11-17 郭松政 Chinese traditional medicine prescription for treating hypertension
CN1628760A (en) * 2004-10-13 2005-06-22 于云龙 Traditional Chinese medicinal formulation for treating cardiovascular and cerebrovascular disease

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1092666A (en) * 1993-03-19 1994-09-28 杨诗琴 A kind of hypotensive palsy-treating preparation and preparation method thereof
CN1546118A (en) * 2003-12-10 2004-11-17 郭松政 Chinese traditional medicine prescription for treating hypertension
CN1628760A (en) * 2004-10-13 2005-06-22 于云龙 Traditional Chinese medicinal formulation for treating cardiovascular and cerebrovascular disease

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