CN101711852B - Traditional Chinese medicine composition for treating injury symptoms of liver cells and preparation method - Google Patents
Traditional Chinese medicine composition for treating injury symptoms of liver cells and preparation method Download PDFInfo
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Abstract
The invention discloses a novel traditional Chinese medicine composition for treating the injury symptoms of liver cells and a preparation method thereof. The traditional Chinese medicine composition mainly comprises the following raw materials of medicines: ganoderma lucidum, radix salviae miltiorrhizae, red peony root, tree peony bark, radix curcumae, safflower, peach kernel, motherwort, draconis sanguis, curcuma, tangerine peel, medicated leaven, malt, rice sprout, fructus amomi, lignum aloe, rosa banksiae, stinkbug, ginseng, American ginseng, crude astragalus root, radix codonopsis pilosulae, white peony root, angelica, radix notoginseng, carapax amydae, tortoise plastron, prepared rehmannia root, tuber fleeceflower, antler, radix polygonati officinalis, noble dendrobium, medlar, schisandra fruit and dogwood. The traditional Chinese medicine composition can be prepared into any common oral preparation according to a conventional traditional Chinese medicine preparation method. The invention can obviously improve the symptoms of liver function abnormity, hepatocirrhosis, hepatic cyst, the pathological changes of the blood vessels of the liver, the internal hemorrhage of the liver, the activity degradation of liver cells, even ascites, edema and the like caused by the injury of stem cells and has definite clinical curative effect, obvious curative effect and quick acting. Because of basically adopting medicine-food homologous medicines specified by the national dispensatory for combination, the traditional Chinese medicine composition has the advantages of low cost, no toxic or side effect basically and the like.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of injury symptoms of liver cells.Relating in particular to a kind of is the Chinese medicine composition and preparation method thereof of the treatment injury symptoms of liver cells of crude drug with the Chinese herbal medicine.
Background technology
Various hepatic disease, poisoning (medicine and chemical toxicant), infection parasite, disturbance of blood circulation, ethanol etc. all can cause injury symptoms of liver cells.As not controlled timely and effectively and being treated, to produce infringement greatly to liver function, as: liver organization hyperemia, edema take place, ooze out, a series of variations such as hepatocellular degeneration and necrosis, and can cause nervous system and cardiovascular infringement, severe patient causes bilirubin encephalopathy or threat to life, and the clinical onset rate has the trend of continuous rising in recent years.
Modern medicine is at clinical a certain symptom treatment, often fall flat, can not find suitable Therapeutic Method, in order to overcome above-mentioned defective, the present invention is based on the differential diagnosis of diseases and the dialectical principle that combines of Chinese traditional treatment injury symptoms of liver cells, treating both the principal and secondary aspects of a disease, deficiency and excess is also controlled, inside and outside logical accent, emergency is taken in concurrently, filter out the natural plant of easing the affected liver yin nourishing, heat-clearing and toxic substances removing, depressed liver-energy dispersing and function of gallbladder promoting,, be prepared from according to certain weight proportion according to the theory of Chinese medical science prescription.A kind of Chinese medicine composition of evident in efficacy, with low cost, treatment injury symptoms of liver cells that toxic and side effects is minimum is provided.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage forms, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be: pill, capsule, tablet, powder, granule or oral liquid etc.
Summary of the invention
Technical problem to be solved by this invention is assorted to overcome above-described shortcoming, and a kind of Chinese medicine composition of treatment injury symptoms of liver cells of evident in efficacy, with low cost, almost non-toxic side effect is provided.
The technical problem of the desired solution of the present invention realizes by following technological approaches.
A kind of Chinese medicine composition for the treatment of injury symptoms of liver cells of the present invention, the component of main following weight portion is formed:
Ganoderma 1～50 gram, Radix Salviae Miltiorrhizae 1～40 gram, Radix Paeoniae Rubra 1～40 gram, Cortex Moutan 1～40 gram, Radix Curcumae 1～40 gram, Flos Carthami 1～30 gram, Semen Persicae 1～30 gram, Herba Leonuri 1～50 gram, Lignum Sappan 1～40 gram, Olibanum 1～30 gram, Myrrha 1～30 gram, Sanguis Draxonis 1～20 gram, Rhizoma Curcumae Longae 1～40 gram, Pericarpium Citri Reticulatae 1～50 gram, Massa Medicata Fermentata 1～50 gram, Fructus Hordei Germinatus 1～50 gram, Fructus Setariae Germinatus 1～50 gram, Fructus Amomi 1～30 gram, Lignum Aquilariae Resinatum 1～30 gram, the Radix Aucklandiae 1～40 gram, Aspongopus 1～30 gram, the Radix Linderae 1～50 gram.
Be preferably:
Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams.
The weight portion consumption of each component of Chinese medicine composition of the present invention can also be:
Radix Ginseng 1～30 gram, Radix Panacis Quinquefolii 1～30 gram, Radix Astragali 1～50 gram, Radix Codonopsis 1～40 gram, the Radix Paeoniae Alba 1～50 gram, Radix Angelicae Sinensis 1～50 gram, Fructus Rosae Laevigatae 1～40 gram, Fructus Alpiniae Oxyphyllae 1～40 gram, Radix Rubiae 1～40 gram, Radix Notoginseng 1～30 gram, Carapax Trionycis 1～30 gram, Carapax et Plastrum Testudinis 1～30 gram, Radix Rehmanniae Preparata 1～40 gram, Radix Polygoni Multiflori 1～50 gram, Colla Corii Asini 1～40 gram, Cornu Cervi Pantotrichum 1～30 gram, Radix Adenophorae (Radix Glehniae) 1～40 gram, Rhizoma Polygonati Odorati 1～40 gram, Herba Dendrobii 1～50 gram, Radix Asparagi 1～50 gram, Radix Ophiopogonis 1～50 gram, Fructus Lycii 1～40 gram, Fructus Schisandrae Chinensis 1～40 gram, Fructus Chebulae's 1～30 gram, Fructus Corni 1～40 gram, Arillus Longan 1～40 gram.
Be preferably:
Radix Ginseng 10 gram, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 gram.
Above-mentioned Chinese medicine composition of the present invention adds various conventional adjuvant required when preparing different dosage form, for example disintegrating agent, lubricant, adhesive etc. are prepared into any oral formulations commonly used with the method for Chinese medicinal of routine, for example can be pill, capsule, tablet, powder, granule or oral liquid etc.
Chinese medicine composition of the present invention is opened one's minds based on traditional Chinese medical science the five internal organs differentiation of syndromes of YIN and YANG guiding principle, in conjunction with safe one and Pu innovation theory system " ten thousand diseases ascent theory ", " the five internal organs differentiation of syndromes of YIN and YANG guiding principle ", " three-dimensional conservation regulation and control rule " and clinical treatment " pairing principle " are as instructing, take place in conjunction with disease, development and the rule that changes, classify according to the original new drug system, formation is monarch with " the five internal organs basic function is adjusted; equilibrium between yin and yang coordination side ", " the main pathogenesis of the five internal organs adjustment side " is minister, " therapy of serious disease side " is assistant, " clinical fundamental symptoms symptomatic treatment side " Chinese medicine patent medicine " original new drug system " for making.
The used herbal raw material medicine of the present invention all can be buied from the Chinese medicine shop, and its specification meets national medical standard.
Usage and dosage: dosage of the present invention depends on concrete dosage form, factors such as patient age, body weight, health status.As guidance: for oral administration: 1) capsule: obey 2～5 every day three times at every turn, every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The treatment that the present invention is directed to the injury symptoms of liver cells patient is very effective, various crude drug are coordinated mutually can play together and are at utmost brought into play drug effect, can effectively improve the self-coordination ability of patient's body, significantly improve function and clinical subjective symptoms, have advantage such as have no side effect, expense is lower in addition.
The specific embodiment
Further describe the present invention by the following examples, it should be understood that these embodiment only are used for the purpose of illustration, never are limited to the present invention.
The preparation of [embodiment 1] capsule
Take by weighing each raw material by following weight portion: Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams, Radix Ginseng 10 grams, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 grams.
Grind into after each component mixing with above-mentioned weight and incapsulate promptly after fine powder is crossed 1500 mesh sieves.
The preparation of [embodiment 2] granule
Take by weighing each raw material by following weight portion: Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams, Radix Ginseng 10 grams, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 grams.
Each raw material of above-mentioned weight fraction is mixed, after grinding into fine powder and crossing 1500 mesh sieves, add ethanol and make adhesive, add starch and do filler, be pressed into granule.
The preparation of [embodiment 3] tablet
Take by weighing each raw material according to following weight portion: Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams, Radix Ginseng 10 grams, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 grams.
Each raw material of above-mentioned weight portion is mixed, after grinding into fine powder and crossing 800～1200 order dusting covers, make tablet promptly.
The preparation of [embodiment 4] pill
Take by weighing each raw material according to following weight portion: Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams, Radix Ginseng 10 grams, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 grams.
Each raw material of above-mentioned weight is mixed, grind into cross 600～1000 mesh sieves behind the fine powder after, make pill promptly.
The preparation of [embodiment 5] oral liquid
Take by weighing each raw material according to following weight portion: Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams, Radix Ginseng 10 grams, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 grams.
Each raw material of above-mentioned weight is mixed, after three decoctions, three filtrates are mixed, filter, be concentrated into rule
Fixed concentration, put cold, the stock solution embedding, irradiation sterilization, after the check, packed products is made oral liquid promptly.
[experimental example] traditional Chinese medicine composition for treating injury symptoms of liver cells of the present invention patient's clinical observation on the therapeutic effect experiment
One, the physical data of experimental subject: adopt Chinese medicine composition of the present invention to treat 37 routine patients altogether, wherein male 24 examples, women 13 examples; The oldest person 65 years old, the age reckling has only 3 years old.
Therapeutic Method:
Usage and dosage: adopt the prepared medicament of the embodiment of the invention, its usage and consumption are as follows: 1) capsule: obey 2～5 every day three times at every turn, and every content of dispersion 0.4 gram, warm water takes.2) tablet: every day three times, each 2～4, every content of dispersion 0.5 gram, warm water takes.3) pill: every day three times, each 5 grams, warm water takes.4) granule: every day three times.Each 5 grams, warm water takes.
The course of treatment: one month is a course of treatment, treats for 9 courses of treatment altogether.
The therapeutic evaluation standard
Cure: sign and symptom are improved fully, and liver function recovery is normal, and each index of correlation is normal, and the patient does not have any bad sensation.
Produce effects: sign and symptom are significantly improved, and liver function recovery is normal substantially, and each index of correlation is near normal, and patient's spirit is fine.
Effectively: the sign change that take a favorable turn, liver function is recovered to some extent, and each index of correlation changes, and random thoughts have discomfort slightly, but can accept, spiritual improvement.
Invalid: sign does not have any change, symptom such as preceding, and liver function does not have improvement, each index of correlation no change.
Model case:
1, Lee, man, 47 years old, cadre.
Suffered from chronic hepatitis before 5 years, through long-term treatment, liver power recovery is normal, but occurs the flushing flushing in zygomatic region recently, continue the low grade fever, pain in the hepatic region, liver function test: glutamate pyruvate transaminase 970U, glutamate-oxaloacetate transaminase 024U, appetite is poor, and abdomen is acute to expand, dizzy, very easily tired, body weight significantly alleviates, loose stool; oliguria with yellow urine, and foul smell is arranged, deep red tongue; white and dry fur like powder gathered, left wiry and frequent pulse, and right stringy pulse is slow.
Take Chinese medicine composition of the present invention after 10 days, the low grade fever removes, and pain in the hepatic region alleviates gradually, surplus disease all alleviates, check liver function: glutamate pyruvate transaminase 750U, glutamic oxaloacetic transaminase, GOT 810U, took Chinese medicine composition of the present invention again 2 months, skin ecchymosis, hepatalgia disappear substantially, and symptom is greatly taken on a new look, check liver function: glutamate pyruvate transaminase 92U, glutamic oxaloacetic transaminase, GOT 78U, continuous clothes Chinese medicine composition of the present invention is surplus March, and symptom all disappears, and it is normal that liver function is recovered fully.
2, become so-and-so, man, 26 years old, office worker.
The patient found the appearance yellowing of the skin before 2 years, food is received not good, is diagnosed as viral icterohepatitis through examination in hospital, and after the treatment, subjective symptoms takes a turn for the better, i.e. stopped treatment.Sclera before February, the little Huang of skin, conscious tired, hepatalgia, aching pain in waist and back, tired postemphasis, complexion does not have the pool, thin white fur of tongue, deep-slow pulse.Western medicines in treatment does not all have significant curative effect, on inspection: icteric index 20U, glutamate pyruvate transaminase 947U, glutamic oxaloacetic transaminase, GOT 740U.
Take Chinese medicine composition of the present invention after 10 days, jaundice disappears, and surplus disease is all to be subtracted, took Chinese medicine composition of the present invention again 15, icteric index 5U, glutamate pyruvate transaminase 650U, glutamic oxaloacetic transaminase, GOT 731U continued clothes Chinese medicine composition of the present invention 1 month, received to increase, icteric index 5U, glutamate pyruvate transaminase 97U, glutamic oxaloacetic transaminase, GOT 68U, continuous clothes Chinese medicine composition of the present invention 3 months, symptom all disappears, and once checks liver function 4 times, all belongs to normal range.
3, Yang, man, 38 years old, cadre.
The hepatitis disease made in 7 years.The bimester before two orders, skin, face xanthochromia appear, the more normal little about 3cm of liver,, icteric index 80U, pain in the hepatic region, face foot edema, dizzy, appetite is poor, feel sick, vomiting, tired, ridge is sent out cold, spontaneous perspiration has creeping chill around umbilicus, and interventral play is expanded under the stomach, desire for hot drinks, big loose stool is thin, oliguria with yellow urine, enlarged tongue is tender, thick fur and be bored with relaxed and soft pulse.
Take Chinese medicine composition of the present invention after 15 days, face foot edema significantly alleviates the hepatic region hypodynia, jaundice goes down, and takes Chinese medicine composition of the present invention again 1 month, and spirit is gradually shaken, the about 1cm of the check more preceding increase of liver, appetite increases, icteric index 25U, continuous clothes Chinese medicine composition of the present invention 1 month, symptom is greatly taken on a new look, and often has a meeting to unit, unconsciously tired, obeyed Chinese medicine composition of the present invention again 1 month, check liver size and every index are all normal, resume work.
4, Zhang, woman, 48 years old, workman.
The patient was diagnosed as the trouble chronic hepatitis before 7 years, multi-treatment does not all have and is clearly better, and the state of an illness repeatedly and increase the weight of the liver function persistent anomaly.When examining, liver function test: glutamate pyruvate transaminase 1180U, glutamate-oxaloacetate transaminase 241U, purpura appears in two lower limb and buttocks, and hepatalgia is felt sick sometimes, is vomitted, the urine frowziness, the complexion HUANGBAI(sic), fatigue and weak, food is received not fragrant, and tongue fur is white slightly, and pulse condition is heavy carefully unable.
Take Chinese medicine composition of the present invention after 20 days, hepatalgia is significantly alleviated, the food of receiving still can, check liver function: glutamate pyruvate transaminase 768U, glutamic oxaloacetic transaminase, GOT 840U took Chinese medicine composition of the present invention again 1 month, and tired symptom is got better, food is received increase, two lower limb and buttocks purpura occurs and obviously reduce, continuous clothes Chinese medicine composition of the present invention 2 months, and purpura, pain disappear substantially; urine is normal; liver function: glutamate pyruvate transaminase 37U, glutamic oxaloacetic transaminase, GOT 64U, it is surplus April to obey Chinese medicine composition of the present invention again; symptom all disappears, and the every index of liver function is all normal on inspection.
5, Feng, man, 50 years old, peasant.
The patient because of abnormal liver function, through " liver is worn ", was diagnosed as chronic hepatitis http://www.haodf.com/jibing/ganya and does not heal before 11 years, and the state of an illness increases the weight of gradually.Self-induction fatigue and weak closely over the past half year, insomnia and dreamful sleep, depressed, hepatalgia, waist soreness is felt sick, vomiting, appetite descends, yellow urine, liver function check: the turbid 16U of Moschus moschiferous, Moschus moschiferous wadding (++), glutamate pyruvate transaminase 960U, glutamic oxaloacetic transaminase, GOT 780U, lusterless complexion, lip is light red dried slightly, deep pulse is counted accurately, and red tongue with thin fur is greasy.
Took Chinese medicine composition of the present invention 15 days, hepatalgia is alleviated, and spirit is gradually shaken, continuous clothes Chinese medicine composition of the present invention 1 month, pain disappears substantially, the turbid 6U of Moschus moschiferous, Moschus moschiferous wadding (+), glutamate pyruvate transaminase 130U, glutamic oxaloacetic transaminase, GOT 97U, it is surplus March to obey Chinese medicine composition of the present invention again, have rosy cheeks, energetic, above-mentioned symptom all disappears, and the check liver function is all normal.
6, grandson so-and-so, woman, 19 years old.
The patient began to suffer from hepatitis before 9 years, once certain hospital's hospitalization 1 year, also once took the treatment by Chinese herbs several months liver function persistent anomaly.So far 9 years surplus, when examining, liver function test: glutamate pyruvate transaminase 580U, glutamic oxaloacetic transaminase, GOT 465U, the turbid 13U of Moschus moschiferous, Moschus moschiferous wadding (+++), food is received general, feels sick sometimes, and loose stool, shallow complexion is simple and unadorned, fatigue and weak, xerostomia, food is received not fragrant, and soreness of waist drowsiness, tongue fur are white slightly, and pulse condition is heavy carefully unable.
Take Chinese medicine composition of the present invention after 20 days, body is tired still to exist, and the food of receiving still can, check liver function: glutamate pyruvate transaminase 268U, glutamate-oxaloacetate transaminase 96U, the turbid 8U of Moschus moschiferous, the Moschus moschiferous wadding (+++), took Chinese medicine composition of the present invention again 1 month, tired symptom is got better, and food is received increase, and the soreness of waist is alleviated gradually, continuous clothes Chinese medicine composition of the present invention 2 months, soreness of waist symptom greatly takes a turn for the better, and stool is normal, liver function: glutamate pyruvate transaminase 58U, glutamic oxaloacetic transaminase, GOT 73U, the turbid 8U of Moschus moschiferous, Moschus moschiferous wadding (++), it is surplus April to obey Chinese medicine composition of the present invention again, symptom all disappears, and the every index of liver function is all normal on inspection.
7, field, woman, 63 years old, retired cadre.
The conscious hepatalgia of beginning before the life-time service anticarcinogen methotrexate, first quarter moon, low grade fever, idol has hematemesis, two lower limbs edema, dysuria, anorexia http://www.aliyiyao.com/food/, food back distension is felt sick, fatigue and weakness, appetite is relatively poor, detests oil white, and pulse condition is heavy carefully unable, liver function test: glutamate pyruvate transaminase 1240U, glutamate-oxaloacetate transaminase 360U.
Took Chinese medicine composition of the present invention 15 days, heating disappears, and hepatalgia is alleviated, continuous clothes Chinese medicine composition of the present invention 1 month, pain disappears substantially, and spirit is gradually shaken, check liver function: glutamate pyruvate transaminase 630U, glutamic oxaloacetic transaminase, GOT 497U, it is surplus March to obey Chinese medicine composition of the present invention again, has rosy cheeks, energetic, above-mentioned symptom all disappears, and the check liver function is all normal.
8, fourth, man, 30 years old, peasant.
Do not have clear and definite inducement and appetite occurs and obviously go down, detest oil, the time nauseating, abdominal distention is arranged, shallow complexion is felt sick, vomiting, appetite descends, and obviously becomes thin, and lethargy is depressed, hepatalgia, the often visible spontaneous oozing of blood of gingiva, two just are with blood, can not be engaged in general physical work.Liver function test: glutamate pyruvate transaminase 720U, glutamic oxaloacetic transaminase, GOT 840U, B ultrasonic is looked into: hepatomegaly, echo is inhomogeneous, a large amount of opaques dark area of fluid of intraperitoneal, abdominal paracentesis is faint yellow glue.
Take Chinese medicine composition of the present invention after 15 days, hepatalgia is alleviated, the spontaneous oozing of blood of gingiva, two just is with blood significantly to alleviate, took Chinese medicine composition of the present invention again 1 month, appetite increases, and spirit takes a turn for the better, and has rosy cheeks, can be engaged in simple physical work, liver function test: glutamate pyruvate transaminase 113U, glutamate-oxaloacetate transaminase 47U, B ultrasonic is looked into: hepatomegaly is little of normal, echo is even, the intraperitoneal opaque dark area of fluid is obviously less, obeys Chinese medicine composition of the present invention again 3 months, and symptom all disappears, can normally work, check: liver size, function are all normal.
Five, therapeutic outcome:
In the 37 routine cases of being accepted for medical treatment,, wherein cure 11 examples through treatment in 9 months, produce effects 15 examples, effective 7 examples, invalid 4 examples, total effective rate reaches 89%.The result shows that Chinese medicine composition of the present invention has extremely significant curative effect to treatment injury symptoms of liver cells patient.
Claims (4)
1. Chinese medicine composition for the treatment of injury symptoms of liver cells, it is characterized in that: its crude drug is made up of following weight portion Chinese medicine:
Ganoderma 30 grams, Radix Salviae Miltiorrhizae 30 grams, Radix Paeoniae Rubra 30 grams, Cortex Moutan 20 grams, Radix Curcumae 20 grams, Flos Carthami 15 grams, Semen Persicae 15 grams, Herba Leonuri 30 grams, Lignum Sappan 15 grams, Olibanum 15 grams, Myrrha 15 grams, Sanguis Draxonis 6 grams, Rhizoma Curcumae Longae 20 grams, Pericarpium Citri Reticulatae 30 grams, Massa Medicata Fermentata 30 grams, Fructus Hordei Germinatus 30 grams, Fructus Setariae Germinatus 30 grams, Fructus Amomi 15 grams, Lignum Aquilariae Resinatum 10 grams, the Radix Aucklandiae 20 grams, Aspongopus 20 grams, the Radix Linderae 30 grams, Radix Ginseng 10 grams, Radix Panacis Quinquefolii 15 grams, Radix Astragali 30 grams, Radix Codonopsis 20 grams, the Radix Paeoniae Alba 30 grams, Radix Angelicae Sinensis 30 grams, Fructus Rosae Laevigatae 20 grams, Fructus Alpiniae Oxyphyllae 30 grams, Radix Rubiae 25 grams, Radix Notoginseng 20 grams, Carapax Trionycis 15 grams, Carapax et Plastrum Testudinis 15 grams, Radix Rehmanniae Preparata 20 grams, Radix Polygoni Multiflori 30 grams, Colla Corii Asini 15 grams, Cornu Cervi Pantotrichum 15 grams, Radix Adenophorae (Radix Glehniae) 25 grams, Rhizoma Polygonati Odorati 20 grams, Herba Dendrobii 20 grams, Radix Asparagi 20 grams, Radix Ophiopogonis 20 grams, Fructus Lycii 30 grams, Fructus Schisandrae Chinensis 30 grams, Fructus Chebulae's 20 grams, Fructus Corni 20 grams, Arillus Longan 15 grams.
2. according to the described Chinese medicine composition of claim 1, it is characterized in that: described Chinese medicine composition is the oral formulations any commonly used that the method for Chinese medicinal according to routine is prepared into.
3. according to claim 1 or 2 described Chinese medicine compositions, it is characterized in that: described oral formulations is pill, capsule, tablet, powder, granule or oral liquid.
4. the application of any described Chinese medicine composition of claim 1～3 in preparation treatment injury symptoms of liver cells medicine.
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| CN103690892A (en) * | 2013-12-23 | 2014-04-02 | 青岛安信医疗器械有限公司 | Traditional Chinese medicine preparation for treating chronic liver diseases |
| CN105943798A (en) * | 2016-06-24 | 2016-09-21 | 胡炜彦 | Application of resina draconis to preparation of medicine for treating acute liver injury caused by hepatectomy |
| US10744173B2 (en) * | 2017-04-14 | 2020-08-18 | Infinitus (China) Company Ltd. | Traditional Chinese medicine compositions for alleviating stress |
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| CN1772257A (en) * | 2005-10-21 | 2006-05-17 | 云南省玉溪望子隆生物制药有限公司 | Fatty liver treating notoginseng prepn and its prepn process |
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Non-Patent Citations (2)
| Title |
|---|
| 郭伟.脂肪肝中医治疗研究进展.《中医药临床杂志》.2007,第19卷(第4期),417-419. * |
| 陈晓莉,等.灵芝及其与丹参、五味子、柴胡配伍对小鼠实验性肝损伤的影响.《第三军医大学学报》.2001,第23卷(第5期),567-570. * |
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