CN101700358A - Medicine for treating acute and chronic nonspecific ulcerative colitis and preparation method thereof - Google Patents
Medicine for treating acute and chronic nonspecific ulcerative colitis and preparation method thereof Download PDFInfo
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Abstract
The invention relates to a medicine for treating acute and chronic nonspecific ulcerative colitis and a preparation method thereof, wherein the medicine is a traditional Chinese medicinal preparation for both oral administration and clyster. The medicine is characterized by comprising the following compositions in parts by weight: 15 to 30 parts of ginseng, 25 to 40 parts of astragalus, 15 to 30 parts of myrobalan flesh, 25 to 40 parts of pomegranate rind, 15 to 25 parts of rhizoma corydalis, 15 to 25 parts of tangerine peel, 15 to 25 parts of costustoot, 15 to 25 parts of liquorice, 20 to 30 parts of lightyellow sophora root, 10 to 20 parts of golden thread, 15 to 25 parts of baical skullcap root, 20 to 30 parts of amur cork-tree bark, 15 to 25 parts of sanchi, 15 to 25 parts of white peony root, 15 to 25 parts of common bletilla rubber, 15 to 25 parts of Chinese gall, 25 to 35 parts of palmy charcoal, and 25 to 35 parts of charred sanguisorba. The traditional Chinese medicines have complementary and synergic effects, and play roles in invigorating qi and strengthening the spleen, astringing intestine and stopping diarrhea, and healing wounds and relieving swelling. The medicine has a total effective rate reaching 98 percent in treating the acute and chronic nonspecific ulcerative colitis.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of acute and chronic nonspecific ulcerative colitis and preparation method thereof.Particularly relate to the Chinese medicine preparation that a kind of coloclysis of holding concurrently for oral administration is used.
Background technology
Acute and chronic nonspecific ulcerative colitis belongs to categories such as Chinese medicine is had loose bowels, spouting bleeding from anus, dysentery, chronic dysentery.How, with the passing of time injure taste because of diseases caused by exogenous pathogenic factor seasonal pathogen, eating and drinking without temperance, disorder of emotion or overstrain, transformation failure of spleen, so that endogenous damp formation, strongly fragrant and heat-transformation, it is rotten and be pus and blood that the large intestine of making a bet, coagulation of QI-blood, blood lose meat, forms the deficiency in origin and excess in superficiality card.The course of disease is longer, and outbreak is frequent, and touching difficulty more.Clinical medicine commonly used has XIANGLIAN ball, Spleen Invigorating and Intestine Tonifying Pill, YUNNAN BAIYAO etc., medicine of the treatment acute and chronic nonspecific ulcerative colitis of describing in the Chinese patent 95100455.7,02116813.X, 200410011206.0,200810104568.2,02104050.8,200810015699.3 etc. and preparation method thereof has certain effect to relief of symptoms or control recurrence.However, the curative effect of these medicines still can not be satisfactory.So still there is demand in the medicine that people better treat acute and chronic nonspecific ulcerative colitis to curative effect.Up to now, the report that does not also have the medicine of the relevant treatment acute and chronic nonspecific ulcerative colitis of the present invention of discovery.The inventor is through research repeatedly for many years, and the checking repeatedly by clinical trial, has found the medicine that the treatment of better curative effect acute and chronic nonspecific ulcerative colitis is arranged finally, thereby has finished the present invention.
Summary of the invention
Purpose of the present invention just provides a kind of medicine for the treatment of acute and chronic nonspecific ulcerative colitis.
Another object of the present invention has provided the preparation method of the medicine of this treatment acute and chronic nonspecific ulcerative colitis.
The choice of drug Radix Ginseng of treatment acute and chronic nonspecific ulcerative colitis of the present invention, the Radix Astragali, QI invigorating ridging, holder skin ulcer granulation promoting add terminalia flesh, Pericarpium Granati, and the dysentery relieving astringing intestine to stop diarrhea is as monarch drug; Selected Rhizoma Corydalis, Pericarpium Citri Reticulatae, the Radix Aucklandiae, Radix Glycyrrhizae again for use, the dissipating blood stasis of regulating the flow of vital energy, solid intestinal pain relieving are as ministerial drug; Also selected Radix Sophorae Flavescentis, Rhizoma Coptidis, Radix Scutellariae, Cortex Phellodendri for use, heat clearing and damp drying, removing pathogenic heat from blood and toxic substance from the body are as adjuvant drug; At last, selected Radix Notoginseng, the Radix Paeoniae Alba, Pseudobulbus Bletillae (Rhizoma Bletillae), Galla Chinensis, charred Petiolus Trachycarpi, charred Radix Sanguisorbae for use, astringing to arrest bleeding, detumescence and promoting granulation are as messenger drug.Act on cooperative compensating between each Chinese medicine, play the effect of air making-up and spleen enlivening, relieving diarrhea with astringents, muscle-growing and detumescence altogether.
The consumption of the drug component of treatment acute and chronic nonspecific ulcerative colitis of the present invention also is to grope to sum up each compositional range that draws in a large number through the inventor to have better curative effect.
According to a kind of medicine for the treatment of acute and chronic nonspecific ulcerative colitis of the present invention, it is characterized in that Chinese medicinal components presses row weight portion proportioning and form: Radix Ginseng 15-30, Radix Astragali 25-40, terminalia flesh 15-30, Pericarpium Granati 25-40, Rhizoma Corydalis 15-25, Pericarpium Citri Reticulatae 15-25, Radix Aucklandiae 15-25, Radix Glycyrrhizae 15-25, Radix Sophorae Flavescentis 20-30, Rhizoma Coptidis 10-20, Radix Scutellariae 15-25, Cortex Phellodendri 20-30, Radix Notoginseng 15-25, Radix Paeoniae Alba 15-25, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-25, Galla Chinensis 15-25, charred Petiolus Trachycarpi 25-35, charred Radix Sanguisorbae 25-35.
Preparation method according to the medicine of described treatment acute and chronic nonspecific ulcerative colitis of the present invention, it is characterized in that taking by weighing the Chinese medicinal components of pressing row weight portion proportioning composition: Radix Ginseng 15-30, Radix Astragali 25-40, terminalia flesh 15-30, Pericarpium Granati 25-40, Rhizoma Corydalis 15-25, Pericarpium Citri Reticulatae 15-25, Radix Aucklandiae 15-25, Radix Glycyrrhizae 15-25, Radix Sophorae Flavescentis 20-30, Rhizoma Coptidis 10-20, Radix Scutellariae 15-25, Cortex Phellodendri 20-30, Radix Notoginseng 15-25, Radix Paeoniae Alba 15-25, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-25, Galla Chinensis 15-25, charred Petiolus Trachycarpi 25-35, charred Radix Sanguisorbae 25-35, with described Chinese medicinal components water extraction 2-3 time extraordinarily by weight, for the first time adding water 1.5-3 doubly measures, soak after 5-12 hour and extracted 1.5 hours, for the second time and add water 1-1.5 for the third time and doubly measure, extracted 1 hour, merge twice or three extracting solution, filter to get filtrate, again filtrate is condensed into 0.5-1 and doubly measures.
Chinese medicinal components according to the amount of drug scope of treatment acute and chronic nonspecific ulcerative colitis of the present invention can also be according to the method for Chinese medicinal of routine, or add required various conventional adjuvant, be prepared into any peroral dosage form commonly used, as pill, tablet, powder, capsule, slow-releasing microcapsule agent etc., or be prepared into any enema commonly used, suppository etc.
The specific embodiment
The following examples and clinical trial can illustrate in greater detail the present invention, but do not limit the present invention in any form.
Embodiment 1:
Chinese medicinal components and consumption: 20 kilograms of Radix Ginsengs, 30 kilograms of the Radixs Astragali, 20 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 25 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 20 kilograms of the Radix Paeoniae Albas, 20 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 30 kilograms of charred Petiolus Trachycarpi, 30 kilograms of charred Radix Sanguisorbae;
Preparation method: above-mentioned Chinese medicinal components is put into extraction pot, extracting in water 3 times, for the first time add 800 kilograms in water, soak after 10 hours, extracted 1.5 hours, collect extracting solution, respectively add 400 kilograms in water for the second time, for the third time, extracted respectively 1 hour, collect extracting solution, the extracting solution concentrating under reduced pressure that merges three times becomes 300 kilograms, is distributed into every bag 100 gram.
Embodiment 2:
Chinese medicinal components and consumption: 25 kilograms of Radix Ginsengs, 30 kilograms of the Radixs Astragali, 25 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 15 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 20 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 15 kilograms of Radix Scutellariaes, 15 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 25 kilograms of the Radix Paeoniae Albas, 25 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 30 kilograms of charred Petiolus Trachycarpi, 30 kilograms of charred Radix Sanguisorbae;
Preparation method: with embodiment 1.
Embodiment 3:
Chinese medicinal components and consumption: 20 kilograms of Radix Ginsengs, 20 kilograms of the Radixs Astragali, 25 kilograms of terminalia flesh, 20 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 25 kilograms of Pericarpium Citri Reticulataes, 25 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 25 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 25 kilograms of Radix Notoginseng, 25 kilograms of the Radix Paeoniae Albas, 20 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 25 kilograms of charred Petiolus Trachycarpi, 25 kilograms of charred Radix Sanguisorbae;
Preparation method: with embodiment 1.
Embodiment 4:
Chinese medicinal components and consumption: 30 kilograms of Radix Ginsengs, 40 kilograms of the Radixs Astragali, 25 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 20 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 25 kilograms of the Radix Paeoniae Albas, 15 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 kilograms of Galla Chinensiss, 20 kilograms of charred Petiolus Trachycarpi, 20 kilograms of charred Radix Sanguisorbae;
Preparation method: with embodiment 1.
Clinical trial
1, clinical data
(1), physical data: observe case totally 308 examples, wherein 260 examples are organized in treatment, male 194 examples, women 66 examples; Matched group 48 examples, male 29 examples, women 19 examples; Age 18-67 year; The course of disease is the longest 18 years, the shortest half a year.
(2), diagnostic criteria: the equal intestinal fiberscopy of all cases, and can the ulcerative colitis academic research can pass through " chronic non-specific ulcerative colitis diagnosis typing and criterion of therapeutical effect " according to national analogy in 1987 and determine.Clinical manifestation is suffered from diarrhoea with lumbago, and mucosanguineous feces is main, and abdominal part especially left lower quadrant has tenderness in various degree, bowel sound hyperaction.Stool is checked pus cell and erythrocyte, and specific pathogen is not found in continuous 3 excrement inspection.Intestinal fiberscopy is found intestinal mucosa hyperemia, edema, hemorrhage, a plurality of ulcer surfaces that as seen vary in size, and there are pus and blood and inflammatory exudate in the surface, narrow, the pseudopolyp of visible enteric cavity in late period etc.The visible diseased region haustra of colon of X line barium enema examination disappears, and intestinal tube is stiff, and the later stage colon shortens, luminal stenosis, and false polyp performance can be arranged.Biopsy is that nonspecific inflammation changes or fibrous scar.
(3), Chinese medical discrimination: according to " the ulcerative colitis diagnostic criteria " of analogy meeting ulcerative colitis scientific seminar of All-China Association of Traditional Chinese Medicine in 1987 formulation.The state of an illness meets the retention of damp-heat in the interior card.
2, Therapeutic Method and usage and dosage
The pharmaceutical preparation that all cases all adopt embodiment of the invention 1-4 method preparation is organized in treatment, and during for oral administration the use 3 times on the 1st, promptly 1 bag of each 100 gram; When coloclysis uses 100 gram medicinal liquids are heated to 37-38 ℃, every day, 1-2 was inferior to morning and evening emptying retention enema greatly after an action of the bowels, retention time 4-8 hour at least.10 days was 1 course of treatment, serve on 3-4 the course of treatment.Finish the course of treatment to check fibro-colonoscope in back 15 days, and drug withdrawal was observed 6 months.The Spleen Invigorating and Intestine Tonifying Pill that matched group adopts Guangzhou old Li Ji pharmaceutical factory to produce, 2 times on the 1st, each 1 ball, and, add 100 milliliters of normal saline, every night 1 retention enema with YUNNAN BAIYAO 10 grams.The course of treatment is the same.
3, criterion of therapeutical effect
Curative effect judging standard according to nineteen ninety-five Ministry of Public Health " the new Chinese medicine clinical research guideline " issued.Recovery from illness: clinical symptom disappearance, colonoscope etc. check that intestinal mucosa recovers normal, observe after the drug withdrawal and do not have recurrence in 6 months.Produce effects: clinical symptoms disappears substantially, and colonoscope etc. check that reaction of intestinal mucosa mild inflammation and part pseudopolyp form.Effectively: inspection mucosa infections such as clinical symptoms and colonoscope take a turn for the better to some extent.Invalid: clinical symptoms and colonoscope etc. inspections do not have improvement.
4, therapeutic outcome
Treatment group clinical recovery 127 examples, produce effects 103 examples, effective 27 examples, invalid 3 examples, total effective rate 98%.Therapeutic process finds no the toxicity of medicine, also do not meet quick reaction takes place.Matched group clinical recovery 9 examples, produce effects 13 examples, effective 9 examples, invalid 17 examples, total effective rate 65%.Both learn by statistics and handle relatively, and difference has highly significant meaning (P＜0.01).
Should be noted that in therapeutic process the state of an illness is alleviated the conditioning that back or convalescent period will be careful in one's diet, avoid cold and uncooked food, Fructus Citri tangerinae, pungent, wine, rich product, avoid clothes milk and milk product, should take food and lack the food of stimulation, easy digestion, high nutrition, keep spiritual optimistic, avoid abdominal part to suffer from cold.
Claims (7)
1. medicine for the treatment of acute and chronic nonspecific ulcerative colitis is characterized in that Chinese medicinal components presses row weight portion proportioning and form: Radix Ginseng 15-30, Radix Astragali 25-40, terminalia flesh 15-30, Pericarpium Granati 25-40, Rhizoma Corydalis 15-25, Pericarpium Citri Reticulatae 15-25, Radix Aucklandiae 15-25, Radix Glycyrrhizae 15-25, Radix Sophorae Flavescentis 20-30, Rhizoma Coptidis 10-20, Radix Scutellariae 15-25, Cortex Phellodendri 20-30, Radix Notoginseng 15-25, Radix Paeoniae Alba 15-25, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-25, Galla Chinensis 15-25, charred Petiolus Trachycarpi 25-35, charred Radix Sanguisorbae 25-35.
2. the medicine of treatment acute and chronic nonspecific ulcerative colitis according to claim 1 is characterized in that Chinese medicinal components presses row weight portion proportioning and form: 20 kilograms of Radix Ginsengs, 30 kilograms of the Radixs Astragali, 20 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 25 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 20 kilograms of the Radix Paeoniae Albas, 20 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 30 kilograms of charred Petiolus Trachycarpi, 30 kilograms of charred Radix Sanguisorbae.
3. the medicine of treatment acute and chronic nonspecific ulcerative colitis according to claim 1 is characterized in that Chinese medicinal components presses row weight portion proportioning and form: 25 kilograms of Radix Ginsengs, 30 kilograms of the Radixs Astragali, 25 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 15 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 20 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 15 kilograms of Radix Scutellariaes, 15 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 25 kilograms of the Radix Paeoniae Albas, 25 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 30 kilograms of charred Petiolus Trachycarpi, 30 kilograms of charred Radix Sanguisorbae
4. the medicine of treatment acute and chronic nonspecific ulcerative colitis according to claim 1 is characterized in that Chinese medicinal components presses row weight portion proportioning and form: 20 kilograms of Radix Ginsengs, 20 kilograms of the Radixs Astragali, 25 kilograms of terminalia flesh, 20 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 25 kilograms of Pericarpium Citri Reticulataes, 25 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 25 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 25 kilograms of Radix Notoginseng, 25 kilograms of the Radix Paeoniae Albas, 20 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 25 kilograms of charred Petiolus Trachycarpi, 25 kilograms of charred Radix Sanguisorbae.
5. the medicine of treatment acute and chronic nonspecific ulcerative colitis according to claim 1 is characterized in that Chinese medicinal components presses row weight portion proportioning and form: 30 kilograms of Radix Ginsengs, 40 kilograms of the Radixs Astragali, 25 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 20 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 25 kilograms of the Radix Paeoniae Albas, 15 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 15 kilograms of Galla Chinensiss, 20 kilograms of charred Petiolus Trachycarpi, 20 kilograms of charred Radix Sanguisorbae.
6. the preparation method of the medicine of the described treatment acute and chronic nonspecific ulcerative colitis of claim 1, it is characterized in that taking by weighing the Chinese medicinal components of pressing row weight portion proportioning composition: Radix Ginseng 15-30, Radix Astragali 25-40, terminalia flesh 15-30, Pericarpium Granati 25-40, Rhizoma Corydalis 15-25, Pericarpium Citri Reticulatae 15-25, Radix Aucklandiae 15-25, Radix Glycyrrhizae 15-25, Radix Sophorae Flavescentis 20-30, Rhizoma Coptidis 10-20, Radix Scutellariae 15-25, Cortex Phellodendri 20-30, Radix Notoginseng 15-25, Radix Paeoniae Alba 15-25, Pseudobulbus Bletillae (Rhizoma Bletillae) 15-25, Galla Chinensis 15-25, charred Petiolus Trachycarpi 25-35, charred Radix Sanguisorbae 25-35, with described Chinese medicinal components water extraction 2-3 time extraordinarily by weight, for the first time adding water 1.5-3 doubly measures, soak after 5-12 hour and extracted 1.5 hours, for the second time and add water 1-1.5 for the third time and doubly measure, extracted 1 hour, merge twice or three extracting solution, filter to get filtrate, again filtrate is condensed into 0.5-1.5 and doubly measures.
7. the preparation method of the medicine of treatment acute and chronic nonspecific ulcerative colitis according to claim 6, it is characterized in that taking by weighing the Chinese medicinal components of pressing row weight portion proportioning composition: 20 kilograms of Radix Ginsengs, 30 kilograms of the Radixs Astragali, 20 kilograms of terminalia flesh, 30 kilograms of Pericarpium Granatis, 20 kilograms of Rhizoma Corydalis, 20 kilograms of Pericarpium Citri Reticulataes, 20 kilograms of the Radix Aucklandiae, 20 kilograms in Radix Glycyrrhizae, 25 kilograms of Radix Sophorae Flavescentiss, 15 kilograms of Rhizoma Coptidis, 20 kilograms of Radix Scutellariaes, 20 kilograms of Cortex Phellodendris, 20 kilograms of Radix Notoginseng, 20 kilograms of the Radix Paeoniae Albas, 20 kilograms of Pseudobulbus Bletillae (Rhizoma Bletillae), 20 kilograms of Galla Chinensiss, 30 kilograms of charred Petiolus Trachycarpi, 30 kilograms of charred Radix Sanguisorbae, described Chinese medicinal components is put into extraction pot, extracting in water 3 times, add for the first time 800 kilograms in water, soak after 10 hours, extracted 1.5 hours, collect extracting solution, for the second time, respectively add 400 kilograms in water for the third time, extracted respectively 1 hour, collect extracting solution, the extracting solution concentrating under reduced pressure that merges three times becomes 300 kilograms, is distributed into every bag 100 gram.
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Cited By (10)
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| CN102988559A (en) * | 2012-12-04 | 2013-03-27 | 娄长丽 | Chinese medicinal enema for treating ulcerative colitis |
| CN103341152A (en) * | 2013-07-31 | 2013-10-09 | 刘建飞 | Traditional Chinese medicine preparation for treating rectocele |
| CN103495031A (en) * | 2013-09-09 | 2014-01-08 | 白石根 | Medicament for treating ulcerative colitis |
| CN103494942A (en) * | 2013-08-20 | 2014-01-08 | 许其树 | Traditional Chinese medicine composition for treating hemorrhoid |
| CN104758763A (en) * | 2015-03-12 | 2015-07-08 | 刘亮 | Qi-regulating and intestine-soothing medicament for treating ulcerative colitis and preparation method thereof |
| CN104857070A (en) * | 2014-02-24 | 2015-08-26 | 贺平 | Pharmaceutical composition used for resisting intestinal tract inflammatory injuries, and preparation method and applications thereof |
| CN104984065A (en) * | 2015-07-10 | 2015-10-21 | 吴斌 | Traditional Chinese medicine for treating ulcerative colitis |
| CN105250821A (en) * | 2015-11-27 | 2016-01-20 | 辽宁中医药大学 | Traditional Chinese medicine compound preparation for treating ulcerative colitis and preparation method thereof |
| CN106334010A (en) * | 2016-10-25 | 2017-01-18 | 孙光周 | Traditional Chinese medicine potion mainly for treating acute and chronic ulcerative colitis and preparation method thereof |
| CN114377071A (en) * | 2022-01-06 | 2022-04-22 | 宋易昕 | Traditional Chinese medicine enema and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102988559B (en) * | 2012-12-04 | 2013-10-30 | 娄长丽 | Chinese medicinal enema for treating ulcerative colitis |
| CN102988559A (en) * | 2012-12-04 | 2013-03-27 | 娄长丽 | Chinese medicinal enema for treating ulcerative colitis |
| CN103341152A (en) * | 2013-07-31 | 2013-10-09 | 刘建飞 | Traditional Chinese medicine preparation for treating rectocele |
| CN103341152B (en) * | 2013-07-31 | 2015-05-27 | 五河县鑫茂种养殖农民专业合作社 | Traditional Chinese medicine preparation for treating rectocele |
| CN103494942A (en) * | 2013-08-20 | 2014-01-08 | 许其树 | Traditional Chinese medicine composition for treating hemorrhoid |
| CN103495031B (en) * | 2013-09-09 | 2016-06-01 | 白石根 | The medicine for the treatment of ulcerative colitis |
| CN103495031A (en) * | 2013-09-09 | 2014-01-08 | 白石根 | Medicament for treating ulcerative colitis |
| CN104857070A (en) * | 2014-02-24 | 2015-08-26 | 贺平 | Pharmaceutical composition used for resisting intestinal tract inflammatory injuries, and preparation method and applications thereof |
| CN104758763A (en) * | 2015-03-12 | 2015-07-08 | 刘亮 | Qi-regulating and intestine-soothing medicament for treating ulcerative colitis and preparation method thereof |
| CN104984065A (en) * | 2015-07-10 | 2015-10-21 | 吴斌 | Traditional Chinese medicine for treating ulcerative colitis |
| CN105250821A (en) * | 2015-11-27 | 2016-01-20 | 辽宁中医药大学 | Traditional Chinese medicine compound preparation for treating ulcerative colitis and preparation method thereof |
| CN105250821B (en) * | 2015-11-27 | 2019-02-26 | 辽宁中医药大学 | A kind of compound Chinese medicinal preparation and preparation method thereof for treating ulcerative colitis |
| CN106334010A (en) * | 2016-10-25 | 2017-01-18 | 孙光周 | Traditional Chinese medicine potion mainly for treating acute and chronic ulcerative colitis and preparation method thereof |
| CN114377071A (en) * | 2022-01-06 | 2022-04-22 | 宋易昕 | Traditional Chinese medicine enema and preparation method thereof |
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