CN101574474A - Traditional Chinese medicine composition for curing purpura - Google Patents

Abstract

The invention relates to a traditional Chinese medicine composition for curing purpura, which takes more than ten types of Chinese herbal medicines as raw materials such as India madder root, Chinese arborvitae twig, yerbadetajo herb, hairyvein agrimonia herb and bud and the like. The traditional Chinese medicine composition has the functions of nourishing yin and reducing pathogenic fire, tranquilizing collaterals and stopping bleeding and is studied and prepared by combining the modern latest scientific research achievements on the basis of the dialectical treatment of the traditional Chinese medicine. The invention aims at providing a traditional Chinese medicine composition for curing purpura, which is characterized by accurate curing effect, safety, convenience, no toxic side effect and low price.

Description

A kind of Chinese medicine composition for the treatment of purpura

Technical field

The present invention relates to a kind of Chinese medicine composition for the treatment of purpura, is that a kind of to treat purpura be the Chinese medicine composition of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Purpura is by injury of small vessels, and blood oozes between skin, the disease of cutaneous manifestations point-like or the livid purple speckle of lamellar.Be equivalent to constitutional thrombocytopenia or vascular, anaphylactoid purpura.Cause that though the reason of purpura is many, study carefully its main person hot fertile, the labor of exteroreception exopathogen, surfeit wine heat to desire body void etc. not several, its pathological change can be summed up as that the gas fire is contrary disorderly, the absurd row of forcing blood and deficient QI failing to control, outer two classes of blood oozing from the body openings or subcuta neous tissue arteries and veins.Pathology character has the branch of deficiency and excess, and can Sthenia is transforming into asthenia.Generally speaking, from the beginning of mostly being wind heat, the high Sheng of gas fire; After the outbreak, cloudy blood consume or " fire is contained impairment of YIN " can be developed into syndrome of hyperactivity of fire due to deficiency of YIN repeatedly.If delay with the passing of time, the blood wound of degassing can transfer syndrome of deficiency of QI, yang deficiency syndrome to.Therefore, in treatment, should grasp and control blood (astringing to arrest bleeding, cooling blood for hemostasis, hemostasis by removing blood stasis), control fire (clearing away heat-fire, nourishing YIN to lower pathogenic fire), control gas (clearing heat in QI system, sending down the abnormal ascending QI, QI invigorating, wet) three big principles, and the first aid process during with massive hemorrhage.The branch wind heat is hindered the network card to the traditional Chinese medical science clinically, heat in blood is hindered disease type Coryza Treated by Syndrome Differentiation such as network card, syndrome of hyperactivity of fire due to deficiency of YIN, syndrome of qi failing to control blood, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of purpura.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

1.5～6 parts of 1.5～6 parts of Gypsum Fibrosum of 1.5～6 parts of Carapax Trionycis of Radix Rehmanniae

1.0～4 parts of 1.0～4 portions of Herba Ecliptaes of 1.0～4 portions of Radix Scrophulariaes of Cacumen Platycladi

1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.0～4 parts of Radix Angelicae Sinensis of Herba Agrimoniae

0.1～2 part of 0.1～2 part of Cortex Moutan of 0.1～2 part of Radix Paeoniae Rubra of Radix Rubiae.

The weight proportion of each crude drug of optimization formula of the present invention is:

2.5～3.5 parts of 2.5～3.5 parts of Gypsum Fibrosum of 2.5～3.5 parts of Carapax Trionycis of Radix Rehmanniae

1.5～2.5 parts of 1.5～2.5 portions of Herba Ecliptaes of 1.5～2.5 portions of Radix Scrophulariaes of Cacumen Platycladi

1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 1.5～2.5 parts of Radix Angelicae Sinensis of Herba Agrimoniae

0.5～1.5 part of 0.5～1.5 part of Cortex Moutan of 0.5～1.5 part of Radix Paeoniae Rubra of Radix Rubiae.

The weight proportion of each crude drug of optimum formula of the present invention is:

3 parts of 3 parts of Gypsum Fibrosum of 3 parts of Carapax Trionycis of Radix Rehmanniae

2 parts of 2 portions of Herba Ecliptaes of 2 portions of Radix Scrophulariaes of Cacumen Platycladi

2 parts of 2 parts of Radix Ophiopogonis of 2 parts of Radix Angelicae Sinensis of Herba Agrimoniae

1 part of 1 part of Cortex Moutan of 1 part of Radix Paeoniae Rubra of Radix Rubiae.

Drug action mechanism among the present invention is as follows:

The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).

The Carapax Trionycis property of medicine is salty, is slightly cold.Return liver, kidney channel.Has nourishing YIN and clearing away heat, suppressing hyper-yang to eliminate wind, the effect of hard masses softening and resolving.Can treat fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, consumption of YIN caused by febrile disease, stirring-up of pathogenic wind in the interior resulting from deficiency, pediatric epilepsy scared, chronic malaria, malaria with splenomegaly ， mass in the abdomen, amenorrhea etc.(the 3369th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Gypsum Fibrosum property of medicine suffering, sweet, cold.Return stomach, lung meridian.Has clearing away heat-fire, the effect that relieving restlessness is quenched the thirst.Can treat the calentura hyperpyrexia, excessive thirst, unconsciousness and delirium is gone mad, and sends out speckle, dyspnea and cough due to lung-heat, heatstroke, stomach-fire headache, toothache, aphtha of the mouth and tongue.Forge then promoting tissue regeneration and ulcer healing, control ulcer sores and burst and not close up burn etc.(the 826th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cacumen Platycladi property of medicine hardship, puckery is slightly cold.Return lung, liver, large intestine channel.Has cooling blood for hemostasis, expelling phlegm for arresting cough, the antidotal effect of dispeling the wind.Can treat haematemesis, epistaxis, hematuria, dysentery, hemorrhoidal hamorrhage, metrorrhagia, cough with copious phlegm, rheumatic arthralgia, alopecia, erysipelas, mumps is scalded etc.(the 1934th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Herba Agrimoniae property of medicine hardship, puckery, flat.Return lung, liver, spleen channel.Has astringing to arrest bleeding, removing food stagnancy dysentery relieving, the effect of removing toxic substances and promoting subsidence of swelling.Can treat spitting of blood, spit blood, epistaxis, hematuria is had blood in stool, metrorrhagia and traumatic hemorrhage, diarrhoea, dysentery is taken off the power impairment caused by overstrain, malaria, furuncle carbuncle, trichomonal vaginitis etc.(the 938th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Rubiae property of medicine hardship, cold.Return liver, heart channel.Has cooling blood for hemostasis, the effect of blood circulation promoting and blood stasis dispelling.Can treat heat in blood spitting of blood, haematemesis, epistaxis, hematuria, have blood in stool, metrorrhagia, amenorrhea, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia, jaundice, carbuncle sore, hemorrhoid are swollen etc.(the 2115th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Cortex Moutan property of medicine hardship, suffering are slightly cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, the effect of promoting blood circulation to remove blood stasis.Can treat the epidemic febrile disease pathogenic heat attacking blood system in febrile diseases, send out speckle, tell nosebleed, the calentura later stage, hot Fu Yin divided heating, osteopyrexia and fever, and amenorrhea due to stagnation of blood, dysmenorrhea, mass in the abdomen, carbuncle sore tumefacting virus falls and pounces on the pain of injury, rheumatic arthralgia etc.(the 1578th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, Carapax Trionycis and Gypsum Fibrosum; With Cacumen Platycladi, Herba Ecliptae, Radix Scrophulariae, Herba Agrimoniae, Radix Angelicae Sinensis and Radix Ophiopogonis is ministerial drug; With Radix Rubiae, Radix Paeoniae Rubra and Cortex Moutan is adjuvant.All medicines are harmonious, altogether tool nourishing YIN to lower pathogenic fire, rather network hemostatic effect.The treatment purpura has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment purpura of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat purpura, and the prevention of purpura is also had good effect, and the treatment purpura has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment purpura; Treatment purpura patient 40 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.30 examples of fully recovering account for 77%, and 6 examples that take a turn for the better account for 15%, and more 4 examples do not account for 10%, and total effective rate reaches 90%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

3 parts of 3 parts of Gypsum Fibrosum of 3 parts of Carapax Trionycis of Radix Rehmanniae

2 parts of 2 portions of Herba Ecliptaes of 2 portions of Radix Scrophulariaes of Cacumen Platycladi

2 parts of 2 parts of Radix Ophiopogonis of 2 parts of Radix Angelicae Sinensis of Herba Agrimoniae

1 part of 1 part of Cortex Moutan of 1 part of Radix Paeoniae Rubra of Radix Rubiae.

Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment purpura that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of purpura is characterized in that it is made by following raw materials by weight proportions:

1.5～6 parts of 1.5～6 parts of Gypsum Fibrosum of 1.5～6 parts of Carapax Trionycis of Radix Rehmanniae

1.0～4 parts of 1.0～4 portions of Herba Ecliptaes of 1.0～4 portions of Radix Scrophulariaes of Cacumen Platycladi

1.0～4 parts of 1.0～4 parts of Radix Ophiopogonis of 1.0～4 parts of Radix Angelicae Sinensis of Herba Agrimoniae

0.1～2 part of 0.1～2 part of Cortex Moutan of 0.1～2 part of Radix Paeoniae Rubra of Radix Rubiae.

2, a kind of Chinese medicine composition for the treatment of purpura according to claim 1, wherein the weight proportion of each crude drug is:

2.5～3.5 parts of 2.5～3.5 parts of Gypsum Fibrosum of 2.5～3.5 parts of Carapax Trionycis of Radix Rehmanniae

1.5～2.5 parts of 1.5～2.5 portions of Herba Ecliptaes of 1.5～2.5 portions of Radix Scrophulariaes of Cacumen Platycladi

1.5～2.5 parts of 1.5～2.5 parts of Radix Ophiopogonis of 1.5～2.5 parts of Radix Angelicae Sinensis of Herba Agrimoniae

0.5～1.5 part of 0.5～1.5 part of Cortex Moutan of 0.5～1.5 part of Radix Paeoniae Rubra of Radix Rubiae.

3, a kind of Chinese medicine composition for the treatment of purpura according to claim 1, wherein the weight proportion of each crude drug is:

3 parts of 3 parts of Gypsum Fibrosum of 3 parts of Carapax Trionycis of Radix Rehmanniae

2 parts of 2 portions of Herba Ecliptaes of 2 portions of Radix Scrophulariaes of Cacumen Platycladi

2 parts of 2 parts of Radix Ophiopogonis of 2 parts of Radix Angelicae Sinensis of Herba Agrimoniae

1 part of 1 part of Cortex Moutan of 1 part of Radix Paeoniae Rubra of Radix Rubiae.