CN101095828A - Chinese traditional medicine composition for treating diabetes constipation - Google Patents

Chinese traditional medicine composition for treating diabetes constipation Download PDF

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Publication number
CN101095828A
CN101095828A CNA2007101183334A CN200710118333A CN101095828A CN 101095828 A CN101095828 A CN 101095828A CN A2007101183334 A CNA2007101183334 A CN A2007101183334A CN 200710118333 A CN200710118333 A CN 200710118333A CN 101095828 A CN101095828 A CN 101095828A
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parts
radix
constipation
chinese medicine
medicine composition
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CNA2007101183334A
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Abstract

The invention relates to a Chinese medicament for treating diabetic constipation which is prepared from more than ten kinds of Chinese medicinal herbs including broomrape, astragalus root, pseudostellaria root and fruit of citron. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.

Description

A kind of Chinese medicine composition for the treatment of diabetic constipation
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of diabetic constipation, is that a kind of diabetic constipation for the treatment of is the Chinese patent medicine of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Diabetic constipation is one of diabetes common complication, and sickness rate is 10%~20%.Pathological changes is in the clinical manifestation of large intestine based on constipation.Diabetic constipation has " difficulty in defecation " in Chinese medicine, " not defecating ", " no defecation ", " stercoroma ", titles such as " spleen-constipation ".Can be summarized as by its cause of disease and pathogenesis: excess syndrome of YANG MING FU-organ, dry stool accumulating in the intestine (functional constipation); Liver temper is strongly fragrant, and (constipation due to disorder of QI) etc. do not fall in the gas of lung stomach is the constipation of excess type card.Asthenia of pulmonosplenic qi, big enteroparesis (constipation due to insufficiency); Deficiency of spleen-YANG and kidneyYANG transmits unable (constipation due to accumulation of pathogenic cold); Blood deficiency is cloudy loses, and intestinal mistake profit (constipation due to insufficiency) etc. are the constipation due to insufficiency card.
The constipation that the constipation of deficiency of both the splenic and pulmonary QI and blood deficiency the moon lose all is called " constipation due to insufficiency " at gold dollar period, comprises blood deficiency and constipation and constipation due to deficiency of QI, is cloudy Tianjin of intestinal and deficiency of YIN-blood, and intestinal loses profit, and it is descending difficult to defecate; Constipation due to deficiency of QI is the large intestine muscular flaccidity, transmits unablely, belongs to the deficiency syndrome category.In a word, the traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation such as functional constipation, constipation due to disorder of QI, constipation due to insufficiency and constipation due to accumulation of pathogenic cold clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of diabetic constipation.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1~2 part of 1.0~4 parts of Radix Et Rhizoma Rhei of 1.5~6 parts of Radix Pseudostellariaes of the Radix Astragali
0.1~2 part in 1.0~4 parts of Natrii Sulfas of 1.5~6 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
0.1~2 part of 1.0~4 parts of Cortex Magnoliae Officinalis of 1.0~4 parts of Radix Rehmanniae of Radix Scrophulariae
0.1~2 part of 1.0~4 parts of Fructus Cannabis of 1.0~4 parts of Herba Cistanches of Fructus Aurantii.
The weight proportion of each raw material of optimization formula of the present invention is:
0.5~1.5 part of 1.5~2.5 parts of Radix Et Rhizoma Rhei of 2.5~3.5 parts of Radix Pseudostellariaes of the Radix Astragali
0.5~1.5 part in 1.5~2.5 parts of Natrii Sulfas of 2.5~3.5 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
0.5~1.5 part of 1.5~2.5 parts of Cortex Magnoliae Officinalis of 1.5~2.5 parts of Radix Rehmanniae of Radix Scrophulariae
0.5~1.5 part of 1.5~2.5 parts of Fructus Cannabis of 1.5~2.5 parts of Herba Cistanches of Fructus Aurantii.
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 parts of Radix Et Rhizoma Rhei of 3 parts of Radix Pseudostellariaes of the Radix Astragali
1 part in 2 parts of Natrii Sulfas of 3 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Rehmanniae of Radix Scrophulariae
1 part of 2 parts of Fructus Cannabis of 2 parts of Herba Cistanches of Fructus Aurantii.
Drug action mechanism among the present invention is as follows:
The Radix Astragali property of medicine is sweet, warm.Return lung, spleen channel.Has benefiting qi and raising yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema, the effect of promoting pus discharge and tissue regeneration strengthening.Can treat the card of all Qi and blood deficiencies, as diarrhea due to hypofunction of the spleen, the cough due to deficiency of the lung, proctoptosis, uterine prolapse, spontaneous perspiration, night sweat, edema, arthralgia due to stagnation of blood, carbuncle is difficult bursts or bursts for a long time and do not hold back etc.(the 2813rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea , mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Scrophulariae property of medicine is sweet, bitter, salty, is slightly cold.Return lung, stomach, kidney channel.Has removing heat from blood, nourishing YIN to lower pathogenic fire, antidotal effect.Can treat the warm febrile disease blood of joining the army, fever of the body, excessive thirst, crimson tongue is sent out speckle, the hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency is insomnia, and constipation is hindered in Tianjin, and order is puckery dim-sighted, laryngopharynx swelling and pain, tuberculous lymphadenitis, skin sore etc.(the 1062nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Fructus Aurantii property of medicine hardship, acid are slightly cold.Return lung, spleen, stomach, large intestine channel.Has the chest stuffiness relieving of regulating the flow of vital energy, the effect of the stagnant removing food stagnancy of row.Can treat the septum pectorale feeling of fullness, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy behind the dysentery, proctoptosis, uterine prolapse etc.(the 2227th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Pseudostellariae property of medicine is slightly cold.Return spleen, lung meridian.Has supplementing QI for promoting the production of body fluid, the effect of spleen reinforcing lung moistening.It is tired to treat insufficiency of the spleen body, inappetence, and impairment of both QI and YIN, dry cough expectorant is few, and spontaneous perspiration is breathed hard, and interior-heat is thirsty, the neurasthenia, palpitation and insomnia, dizzy forgetful, children's's summer fever etc.(the 534th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Herba Cistanches property of medicine is sweet, salty, temperature.Return kidney, large intestine channel.Has kidney-replenishing, benefiting essence-blood, the effect in intestine moistening road.Can treat the sexual impotence of kidney yang deficiency, asthenia of essence and blood, seminal emission, nebulousurine, the frequent micturition heeltap, the lumbago flaccidity of the lower limbs, tinnitus order flower, menstruation is spread out the phase, infertility, dryness of the intestine constipation etc.(the 1226th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal , lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Natrii Sulfas nature and flavor are salty, bitter, and are cold.Return stomach, large intestine channel.Has purging heat to relax the bowels, moistening for dryness and softening hard mass, the repercussive effect of relieving inflammation or internal heat.Can treat the excess-heat constipation, constipation due to dry stool, stagnant stomachache, acute appendicitis swells and ache; The external treatment acute mastitis, swelling and pain of hemorrhoid etc.(the 96th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
Cortex Magnoliae Officinalis property of medicine hardship, suffering, temperature.Return stomach, large intestine channel.Has the circulation of qi promoting intestinal stasis relieving, dampness, the effect of lowering the adverse QI to relieve asthma.Can treat stagnation of QI due to dyspepsia, abdominal distention constipation, retention of dampness in middle-JIAO, the gastral cavity painful abdominal mass is vomited and diarrhoea, and expectorant is stopped up QI rising in reverse order, and fullness in the chest is breathed with cough etc.(the 2284th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Fructus Cannabis nature and flavor are sweet, and are flat.Return spleen, stomach, large intestine channel.Effect with loosening bowel to relieve constipation.Can treat blood deficiency and depleted fluid, dryness of the intestine constipation etc.(the 60th page of Chemical Industry Press of Pharmacopoeia of the People's Republic of China version in 2000 is compiled by Chinese Pharmacopoeia Commission).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", with the Radix Astragali with when being classified as monarch drug; With Radix Pseudostellariae, Radix Scrophulariae, Radix Rehmanniae, Radix Ophiopogonis, Radix Et Rhizoma Rhei, Fructus Aurantii and Herba Cistanches is ministerial drug; With Natrii Sulfas, Cortex Magnoliae Officinalis and Fructus Cannabis is adjuvant.All medicines are harmonious, and are total to the tool supplementing QI and nourishing YIN, the effect of loosening bowel to relieve constipation.The treatment diabetic constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function treatment diabetic constipation of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat diabetic constipation, and the prevention of diabetic constipation is also had good effect, and the treatment diabetic constipation has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment diabetic constipation; Treatment diabetic constipation patient 25 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.10 examples of fully recovering account for 40%, and 13 examples that take a turn for the better account for 52%, and invalid 2 examples account for 8%, and total effective rate reaches 92%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
1 part of 2 parts of Radix Et Rhizoma Rhei of 3 parts of Radix Pseudostellariaes of the Radix Astragali
1 part in 2 parts of Natrii Sulfas of 3 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Rehmanniae of Radix Scrophulariae
1 part of 2 parts of Fructus Cannabis of 2 parts of Herba Cistanches of Fructus Aurantii.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment diabetic constipation that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.

Claims (3)

1, a kind of Chinese medicine composition for the treatment of diabetic constipation is characterized in that it is made by the following weight proportion raw material:
0.1~2 part of 1.0~4 parts of Radix Et Rhizoma Rhei of 1.5~6 parts of Radix Pseudostellariaes of the Radix Astragali
0.1~2 part in 1.0~4 parts of Natrii Sulfas of 1.5~6 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
0.1~2 part of 1.0~4 parts of Cortex Magnoliae Officinalis of 1.0~4 parts of Radix Rehmanniae of Radix Scrophulariae
0.1~2 part of 1.0~4 parts of Fructus Cannabis of 1.0~4 parts of Herba Cistanches of Fructus Aurantii.
2, a kind of Chinese medicine composition for the treatment of diabetic constipation according to claim 1, wherein the weight proportion of each raw material is:
0.5~1.5 part of 1.5~2.5 parts of Radix Et Rhizoma Rhei of 2.5~3.5 parts of Radix Pseudostellariaes of the Radix Astragali
0.5~1.5 part in 1.5~2.5 parts of Natrii Sulfas of 2.5~3.5 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
0.5~1.5 part of 1.5~2.5 parts of Cortex Magnoliae Officinalis of 1.5~2.5 parts of Radix Rehmanniae of Radix Scrophulariae
0.5~1.5 part of 1.5~2.5 parts of Fructus Cannabis of 1.5~2.5 parts of Herba Cistanches of Fructus Aurantii.
3, a kind of Chinese medicine composition for the treatment of diabetic constipation according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 parts of Radix Et Rhizoma Rhei of 3 parts of Radix Pseudostellariaes of the Radix Astragali
1 part in 2 parts of Natrii Sulfas of 3 parts of Radix Ophiopogonis of Radix Angelicae Sinensis
1 part of 2 parts of Cortex Magnoliae Officinalis of 2 parts of Radix Rehmanniae of Radix Scrophulariae
1 part of 2 parts of Fructus Cannabis of 2 parts of Herba Cistanches of Fructus Aurantii.
CNA2007101183334A 2007-07-05 2007-07-05 Chinese traditional medicine composition for treating diabetes constipation Pending CN101095828A (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101628056B (en) * 2009-08-05 2011-04-20 刘志美 Compound composition for treating diabetic constipation
CN104491710A (en) * 2014-12-10 2015-04-08 丁铁梅 Traditional Chinese medicine for treating constipation
CN104800582A (en) * 2015-05-13 2015-07-29 关庆玲 Traditional Chinese medicine for treating internal heat due to yin deficiency type diabetic constipation
CN104983980A (en) * 2015-07-10 2015-10-21 宋云飞 Traditional Chinese medicine for treating diabetic coprostasis
CN105831559A (en) * 2016-03-22 2016-08-10 王勇智 Hypoglycemic food and using method thereof
CN107496688A (en) * 2017-08-30 2017-12-22 胡杰红 A kind of Chinese medicine composition for treating diabetes treaitng Yin-deficiency constipation

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101628056B (en) * 2009-08-05 2011-04-20 刘志美 Compound composition for treating diabetic constipation
CN104491710A (en) * 2014-12-10 2015-04-08 丁铁梅 Traditional Chinese medicine for treating constipation
CN104800582A (en) * 2015-05-13 2015-07-29 关庆玲 Traditional Chinese medicine for treating internal heat due to yin deficiency type diabetic constipation
CN104983980A (en) * 2015-07-10 2015-10-21 宋云飞 Traditional Chinese medicine for treating diabetic coprostasis
CN105831559A (en) * 2016-03-22 2016-08-10 王勇智 Hypoglycemic food and using method thereof
CN107496688A (en) * 2017-08-30 2017-12-22 胡杰红 A kind of Chinese medicine composition for treating diabetes treaitng Yin-deficiency constipation
CN107496688B (en) * 2017-08-30 2020-12-01 胡杰红 Traditional Chinese medicine composition for treating diabetes yin deficiency constipation

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Open date: 20080102