CN101112436A - Chinese medicine preparation for treating bacchia - Google Patents

Abstract

The present invention relates to a traditional Chinese medicine preparation for treating rosacea, which takes more than 10 Chinese herbal medicines of Chinese gentian, raw gypsum, lightyellow sophora root and fried gardenia etc. as the raw materials. The present invention has the effects of clearing fever and fire, dispelling wind and arresting itch. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results and the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine preparation for treating rosacea. The present invention is characterized by accurate efficacy, safety, convenience, low price and no toxicity or side effects.

Description

A kind of Chinese medicine preparation of treatment rosacea

Technical field

The present invention relates to treat a kind of Chinese medicine preparation of rosacea, is that a kind of rosacea for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.

Background technology

Rosacea has another name called acne rosacea, the schlempe acne.It is the chronic skin disease due to the long-term expansion of local skin blood capillary that causes of vasomotor nerve imbalance.The skin lesion characteristics are the diffusivity erubescence, with pimple, pustule and telangiectasis etc.Because of it betides face, the most remarkable with nose portion especially, so had a strong impact on facial appearance.The traditional Chinese medical science claims that primary disease is acne rosacea, wine Zha nose, acne rosacea etc., is commonly called as coppernose, brandy nose.The cause of disease of rosacea is still not exclusively clear, may be on seborrheal basis because the effect of the various injurious factors in the inside and outside boundary of body makes the imbalance of face vasomotor nerve, the long-term result who expands of blood capillary.Common various injurious factor comprises: be addicted to drink, demodex folliculorum parasitism etc. in pungent irritable food, strong tea, coffee, cocoa, gastrointestinal dysfunction, focal infection, high temperature or cold stimulation, Nervous and Mental Factors, dyshormonia, cardiovascular disease, the pore.The traditional Chinese medical science thinks, many being gone up by the long-pending heat of lung stomach of primary disease steamed, the exterior tightened by pathogenic windcold whenever, and blood stasis condenses and forms.Or the pungent stimulation food of diet, the people that is addicted to drink, fume is stifling, meets the heresy of wind and cold again, hands over due to the resistance skin.The traditional Chinese medical science is divided disease type Coryza Treated by Syndrome Differentiation clinically, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.

Summary of the invention

The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of rosacea.Have determined curative effect, safe ready, have no side effect, cheap characteristics.

The present invention is made by following raw materials by weight proportions:

0.1～2 part of 1.0～4 portions of Bombyx Batryticatus of 1.5～6 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

0.1～2 part of 1.0～4 parts of Radix Et Rhizoma Rhei of 1.0～4 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

0.1～2 part of 0.1～2 portion of Radix Gentianae of 1.0～4 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

0.1～2 part of 0.1～2 part of Radix Glycyrrhizae of 1.0～4 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.

The weight proportion of each crude drug of optimization formula of the present invention is:

0.5～1.5 part of 1.5～2.5 portions of Bombyx Batryticatus of 2.5～3.5 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

0.5～1.5 part of 1.5～2.5 parts of Radix Et Rhizoma Rhei of 1.5～2.5 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

0.5～1.5 part of 0.5～1.5 portion of Radix Gentianae of 1.5～2.5 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

0.5～1.5 part of 0.5～1.5 part of Radix Glycyrrhizae of 1.5～2.5 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.

The weight proportion of each crude drug of optimum formula of the present invention is:

1 part of 2 portions of Bombyx Batryticatus of 3 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

1 part of 2 parts of Radix Et Rhizoma Rhei of 2 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

1 part of 1 portion of Radix Gentianae of 2 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

1 part of 1 part of Radix Glycyrrhizae of 2 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.

Drug action mechanism among the present invention is as follows:

Gypsum Fibrosum property of medicine suffering, sweet, cold.Return stomach, lung meridian.Has clearing away heat-fire, the effect that relieving restlessness is quenched the thirst.Can treat the calentura hyperpyrexia, excessive thirst, unconsciousness and delirium is gone mad, and sends out speckle, dyspnea and cough due to lung-heat, heatstroke, stomach-fire headache, toothache, aphtha of the mouth and tongue.Forge then promoting tissue regeneration and ulcer healing, control ulcer sores and burst and not close up burn etc.(the 826th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Fructus Gardeniae (parched) property of medicine hardship, cold.GUIXIN, liver, lung, stomach, tri-jiao channel.Has the pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, the effect of removing pathogenic heat from blood and toxic substance from the body.It is vexed to treat calentura, the liver-fire conjunctival congestion, and headache, jaundice due to damp-heat, stranguria is spitted blood, epistaxis, dysentery, hematuria, aphtha of the mouth and tongue, sore swollen toxin is sprained and is swollen and ache etc.(the 2242nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Arnebiae (Radix Lithospermi) property of medicine hardship, cold.GUIXIN, Liver Channel.Has removing heat from blood and promoting blood circulation, the effect of detoxifcation rash.Can treat haematemesis, epistaxis, hematuria, purpura, macule, measles, jaundice, carbuncle is scalded etc.(the 3272nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Paeoniae Rubra property of medicine hardship is slightly cold.Return liver, spleen channel.Has clearing away heat and cooling blood, the effect of blood circulation promoting and blood stasis dispelling.Can treat maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, the carbuncle skin infection, amenorrhea, dysmenorrhea, the metrorrhagia and leukorrhagia stranguria with turbid discharge, the stasis of blood hypochondriac pain that stagnates, the hernia abdominal mass is gathered, injury from falling down etc.(the 1440th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Radix Angelicae Sinensis property of medicine is sweet, hot, bitter, temperature.Return liver, the heart, spleen channel.Having enriches blood invigorates blood circulation, menstruction regulating and pain relieving, the effect of moisturizing laxation.Can treat all cards of blood deficiency, menoxenia, amenorrhea, dysmenorrhea ， mass in the abdomen knot is poly-, metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, the dryness of the intestine dyschezia, heavy after the bloody dysentery, ulcer sores, injury from falling down etc.(the 1210th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The little hardship of the Herba Artemisiae Scopariae property of medicine, little suffering are slightly cold.Return spleen, stomach, urinary bladder channel.Has clearing away heat-damp and promoting diuresis, the effect of jaundice eliminating.Can treat jaundice, dysuria, eczema pruritus etc.(the 2146th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The Periostracum Cicadae property of medicine is sweet, salty, cold.Return lung, Liver Channel.Has dispelling wind-heat, rash sore-throat relieving, the effect of expellingging wind and relieving convulsion.Can treat anemopyretic cold, laryngopharynx swelling and pain, the cough hoarseness, measles without adequate eruption, the rubella pruritus, the conjunctival congestion cataracta, infantile convulsion is twitched, tetanus etc.(the 3599th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Sophorae Flavescentis property of medicine hardship, cold.GUIXIN, lung, kidney, large intestine channel.Has heat clearing and damp drying, the effect of wind dispelling insecticide.Can treat damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.(the 1758th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Bombyx Batryticatus property of medicine suffering, salty, flat.Return liver, lung, stomach warp.Have and expelling wind and relieving convulsion, dissipating phlegm and resolving masses, the effect of resolving toxin and disinhibiting the throat.Infantile convulsion be can treat and apoplexy facial hemiparalysis, migraine and general headache, laryngopharynx swelling and pain, scrofula, mumps, rubella, sore etc. twitched.(the 1021st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Et Rhizoma Rhei property of medicine hardship, cold.Return stomach, large intestine, liver, spleen channel.Have attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, antidotal effect.Can treat the food stagnation constipation, the accumulation of heat feeling of stuffiness in chest; Damp-heat dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria; Conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, gastropyretic vomiting; Spit blood, spitting of blood, epistaxis is had blood in stool, hematuria; Blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal ， lumps in the chest and abdomen, traumatic injury; Pyretic toxicity carbuncle and ulcer, erysipelas is scalded etc.(the 141st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

Radix Gentianae nature and flavor hardship, cold.Return liver, gallbladder meridian.Have eliminating pathogen in the liver gallbladder fire, the clear part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels is wet, relieving convulsion making eye bright, and the malaria protozoon is good for the stomach, the effect that protects the liver.Can treat that Liver Channel intenseness of heat, infantile convulsion are manic, encephalitis B, headache, conjunctival congestion, pharyngalgia, jaundice, hematodiarrhoea, the swollen skin infection of pain, scrotum swell and ache, pudendum pruritus due to damp pathogen, hypertension, dizziness and tinnitus, chest and hypochondrium, acute infectious hepatitis, cystitis, skin infection swell and ache etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 413rd page).

The Radix Glycyrrhizae property of medicine is sweet, and is flat.Return spleen, stomach, the heart, lung meridian.Have and middle emergency lung moistening, detoxifcation, the effect of coordinating the actions of various ingredients in a prescription.Can treat weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, hysteria, consumptive lung disease cough; Give birth to controlling laryngopharynx swelling and pain, the carbuncle pyogenic infections from tumour or sore, infantile carbuncle reaches medicine, alimentary toxicosis etc.(the 792nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).

The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Gypsum Fibrosum, Radix Gentianae and Radix Sophorae Flavescentis; With Radix Angelicae Sinensis, Radix Paeoniae Rubra, Periostracum Cicadae, Radix Arnebiae (Radix Lithospermi), Fructus Gardeniae (parched) and Herba Artemisiae Scopariae is ministerial drug; With Bombyx Batryticatus, Radix Et Rhizoma Rhei and Radix Glycyrrhizae is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat-fire, the effect of dispelling wind for relieving itching.The treatment rosacea has determined curative effect, has no side effect taking convenience, cheap characteristics.

Clinical drug of the present invention uses the result to show that following advantage is arranged:

1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment rosacea of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.

2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.

3, the present invention not only can effectively treat rosacea, and the prevention of rosacea is also had good effect, and the treatment rosacea has determined curative effect, has no side effect taking convenience, cheap characteristics.

For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the treatment rosacea; Treatment rosacea patient 18 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 44.44%, and 9 examples that take a turn for the better account for 50%, and more 1 example does not account for 5.55%, and total effective rate reaches 94.44%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.

The specific embodiment

The embodiment decoction is pressed following weight weighting raw materials:

1 part of 2 portions of Bombyx Batryticatus of 3 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

1 part of 2 parts of Radix Et Rhizoma Rhei of 2 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

1 part of 1 portion of Radix Gentianae of 2 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

1 part of 1 part of Radix Glycyrrhizae of 2 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.

Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment rosacea that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. a kind of Chinese medicine preparation of treatment rosacea is characterized in that it is made by following raw materials by weight proportions:

0.1～2 part of 1.0～4 portions of Bombyx Batryticatus of 1.5～6 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

0.1～2 part of 1.0～4 parts of Radix Et Rhizoma Rhei of 1.0～4 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

0.1～2 part of 0.1～2 portion of Radix Gentianae of 1.0～4 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

0.1～2 part of 0.1～2 part of Radix Glycyrrhizae of 1.0～4 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.

2. a kind of Chinese medicine preparation of treatment rosacea according to claim 1, wherein the weight proportion of each crude drug is:

0.5～1.5 part of 1.5～2.5 portions of Bombyx Batryticatus of 2.5～3.5 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

0.5～1.5 part of 1.5～2.5 parts of Radix Et Rhizoma Rhei of 1.5～2.5 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

0.5～1.5 part of 0.5～1.5 portion of Radix Gentianae of 1.5～2.5 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

0.5～1.5 part of 0.5～1.5 part of Radix Glycyrrhizae of 1.5～2.5 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.

3. a kind of Chinese medicine preparation of treatment rosacea according to claim 1, wherein the weight proportion of each crude drug is:

1 part of 2 portions of Bombyx Batryticatus of 3 parts of Radix Angelicae Sinensis of Gypsum Fibrosum

1 part of 2 parts of Radix Et Rhizoma Rhei of 2 portions of Herba Artemisiae Scopariaes of Fructus Gardeniae (parched)

1 part of 1 portion of Radix Gentianae of 2 portions of Periostracum Cicadaes of Radix Arnebiae (Radix Lithospermi)

1 part of 1 part of Radix Glycyrrhizae of 2 parts of Radix Sophorae Flavescentiss of Radix Paeoniae Rubra.