CN101537147B - Anaesthetic prescription for treating pulmonary tuberculosis and preparation method thereof - Google Patents
Anaesthetic prescription for treating pulmonary tuberculosis and preparation method thereof Download PDFInfo
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Abstract
The invention discloses an anaesthetic prescription for treating pulmonary tuberculosis and a preparation method thereof. Potentilla discolor, rhizoma polygonati, radix codonopsitis, colla asini, deerhorn glue, self-heal, schizonepeta, Chinese holly leaf, bletilla, stemona root, mugwort leaf, gallus domesticus brisson and liquorice taken as raw materials are subjected to the treatment of crushing, alcohol extraction, water extraction and the like respectively according to different characteristics of each gout of medicament to form capsules, tablets, pills or granules. The anaesthetic prescription has unique formula and obvious treatment effect, improves the immunity of the organism, and has no adverse reaction.
Description
Technical field
(illiteracy) medicine formulation art specifically relates to a kind of method for preparing of treating phthisical mongolian medicine and solid preparation thereof in the invention belongs to.
Background technology
Pulmonary tuberculosis is a kind of chronic disease, frequently-occurring disease, commonly encountered diseases, is that tubercule bacillus is immersed a kind of disease that lung tissue causes.The traditional Chinese medical science is claimed pulmonary's consumptive disease, is to immerse due to the pulmonary because of the consumptive disease worm.
At present, in clinical medicine, the treatment pulmonary tuberculosis mostly adopts Western medicine west coupling method to suppress the purpose that tubercule bacillus reaches treatment.Oral drugs commonly used have isoniazid, rifampicin, ethambutol, pyrazinamide, the intravenous drip sodium aminosalicylate, and the intramuscular injection streptomycin changes two kinds of medications the continuous use 4-6 month later on into, omnidistance medication 1-2.Though tubercule bacillus is had the inhibition killing action, and the course of treatment is long, resistant rate is high, and toxic and side effects is big, and long-term prescription all has infringement in various degree to digestive system, liver, brain, kidney, nervus centralis.Common clinically to not adhering to whole-course treatment strongly because of adverse effect, cause treating not thorough and the case of recurrence; Also some patient's tuberculosis is not cured as yet, and drug intoxication property disease is quite serious.Therefore, development is not only pressing for of treatment than safer, the more effective new drug of chemical drugs, and has great social significance.
Summary of the invention
One, medicine of the present invention is the phthisical mongolian medicine of a kind of treatment, and its prescription is made up of the following weight proportion raw material:
The present invention has following characteristics: choice of drug natural plants of the present invention is a raw material, has the effect that suppresses tubercule bacillus, enhancing human body immunity power.This medicine can be united use separately or with the tuberculosis Western medicine according to the concrete situation of patient, and evident in efficacy, the course of treatment is shorter, does not have any untoward reaction, can alleviate or eliminate complication significantly.This medicine each item technical specification meets from the quality standard of intending, and meets the regulation of solid preparation under the version Chinese Pharmacopoeia item in 2005.
1, immunological testing proves: this medicine can improve the lymphocytic immunologic function of T.The immune indexes data of low dose group and positive controls LINGZHI JIAONANG are approaching basically, are respectively 27% and 26.9%; Middle dose groups immune indexes is 30.6%, is higher than the data of matched group.Low dose group and middle dose groups make mice strengthen the conversion reaction of phytohaemagglutinin, and lymphoblast percentage rate and matched group do not have significant difference.This medicine phagocytosis is more stable, and the phagocytosis enhancing of low dosage and middle dose groups all is higher than matched group, and high dose group and matched group are suitable.
2, the experiment in vitro result shows: this medicine has certain antibacterial, a bacteriostasis external.This medicine has certain statistical significance to the mouse model of infection due to Mycobacterium tuberculosis on organ weights index (middle dose groups) and two indexs of lung bacterium separation number (high meter dose groups).
3, The acute toxicity tests shows: this poison of drug property is lower.Give mouse stomach with adult's (60kg) clinical consumption per day (0.19g/kg), can't measure LD50; Content suspension with Cmax (30%) is given mouse stomach 0.5ml/10g, and 3 times/day, observed continuously 14 days, the result shows that mice oral maximum dosage-feeding every day is 45g/kg, is equivalent to 237 times of clinical adult's dosage.
4, the long term toxicity test result shows: long-term this medicine of large dose oral administration is to equal free of toxic effects such as the behavioral activity of animal, growth promoter, organ-tissue, hepatic and renal function, blood system, so this medicine is safe with the dosage use of clinical recommendation.Serve as test rat 26 weeks of successive administration with 6.0g/kg.d (be equivalent to be grown up clinical consumption every day 30 times), 3.0g/kg.d (be equivalent to be grown up clinical consumption every day 15 times), 2.0g/kg.d (be equivalent to be grown up clinical consumption every day 10 times) dose groups respectively, the result: none example is dead; Each organizes general state, food-intake, body weight, hematology and blood biochemical each item index, the equal no abnormality seen of main organs index of rat; System's postmortem and pathological tissue inspection, administration group rat is examined organ and matched group does not have obvious difference yet.After 2 all drug withdrawals recoveries, administration is respectively organized each item index and is compared no evident difference with matched group.
5, clinical practice situation
This prescription is on the basis of handed down from the older generations of the family proved recipe, is guidance with Mongolian medicine's mongolian medicine theory, absorb to use for reference theory of Chinese medical science and treatment experience, in conjunction with clinical observation for many years, further improves and confirms.Clinical observation confirms that this medicine (medicine is called the anti-consumptive disease ball of compound recipe) treatment pulmonary tuberculosis is compared with chemotherapy, has significant advantage, mainly shows: the one, have no untoward reaction, drug safety; The 2nd, the course of treatment is shorter, and morbidity example just just can be cured through 2-4 month fully, can cure basically in recurrent cases and critical case 4-6 month; The 3rd, recurrent cases evident in efficacy, invalid to chemotherapy, and the critical case that serious complication is arranged all have definite curative effect.Some cases brief introduction (this medicine anti-consumptive disease ball of compound recipe by name in clinical):
One of case: Sai Jierfu, the man, the herdsman lives white tone stannum and reins in 7 another arenaes, pasture, and on August 25th, 1996 examined, and 34 years old, telephone number: 0479-8826512, Huang Hu changes Sai Jierfu.
According to stating, the patient suffers from cough, chest pain at the beginning of 1991, be diagnosed as infiltrative pulmonary tuberculosis in hospital of stannum alliance, and is apparent through the hospitalization curative effect, after hospital, Chifeng City tuberculosis hospital fail to respond to any medical treatment in the Linxi County again.On April 8th, 1996, the Inner Mongol chest hospital hospitalization of transferring from one hospital to another, the left lung epimere excision of row on August 23 was left hospital to JIUYUE 18, and the x mating plate shows the full lung TB focus that extensively distributes when leaving hospital.Nikkei was told cloth and stepped on to introduce and examine first visit JIUYUE 21: cough, expectorant are thick, apoplexy due to phlegm has blood, chest pain, stomachache, abdominal distention, inappetence.Every meal can only be eaten gruel one little bowl, hyperhidrosis, and general weakness, big dry stool, yellow urine, red tip of the tongue, yellow fur is thick, thready and rapid pulse, auscultation is fine rale, palpation, liver is 2cm under arcus costarum, and abdominal part is swollen full, transaminase 89 Ц (Lai Shi).
The diagnosis: active stage pulmonary tuberculosis.
Treatment: the anti-consumptive disease ball of (1) compound recipe, 19 of every clothes, 2 times/day.
(2) raise with transaminase due to the Western medicine for a long time to it, stomachache, flatulence, symptoms such as inappetence add that dried feces of Sus scrofa L. ten flavors loose, the wooden Sa Si flavor of letter soup, the white ball of manna, Flos Carthami 13 flavors are diffusing.
Examine on October 15 two, stomachache, flatulence disappears, inappetence, chest pain, cough alleviates, and satisfies dried feces of Sus scrofa L. ten flavors of stopping using and looses, and pricks wooden Sa Si flavor soup, the white ball of manna, red medicine 13 flavors and looses, continue with anti-consumptive disease pill for curing, consumption increase to 31/inferior, 2 times/day.To transference cure on January 10th, 1997, obey anti-consumptive disease ball after 3 months, the x mating plate shows the whole calcifications of focus and drug withdrawal, follows up a case by regular visits to so far not recurrence, and participates in various physical works as ordinary person always.
Two of case: its wooden lattice, the woman, the herdsman, the Mongols lives Abaga Banner white tone Guo Le Lignum Sappan antiperspirant crow and draws loud, high-pitched sound to look into, December was examined on the 11st in 1999, the time 32 years old year, no telephone number.
In household generation, tell, and postinfectious cough at the beginning of 1992, chest pain, night sweat are more than, and hospital is diagnosed as and invades profit type pulmonary tuberculosis to the Abaga Banner, and half a year, symptom disappeared basically in hospital.After several times recurrence, several times hospitalization state of an illness day is heavy.The hospital of stannum alliance of transferring from one hospital to another in November, 1999 is diagnosed as the infiltrative type cavernous pulmonary tuberculosis of holding concurrently, and hospitalization is seen massive hemoptysis to beginning November 23; The about 250ml-350ml of spitting of blood amount every day, vomiting can not be had a meal and drink water; As have a meal to drink water and then cause strong vomiting, lean on liquid-retentive entirely, school sent the notice of being critically ill on the 8th in December; Do not feel any better through rescuing the state of an illness, left hospital in 11st in December and examine.Examine and see that whole body is worn to a shadow, scaly dry skin, dim complexion is unable to leave the bed, and head and extremity can not autonomic activitieses, the low not audible of language, cough is panted, weak breathing in critical.Yellow fur is thick, and root is burned black, and prickle is arranged, six deep-hidden pulse.Satisfy and suddenly to cast medicine in case sudden cardiac arrest, hemostasis, emesis are recovered gastric qi.
Take following decoction according to above symptom:
(1) Radix Ginseng 10g, Radix Ophiopogonis 12g, Fructus Schisandrae Chinensis 8g, Placenta Hominis dry powder 10 (grind into powder and take after mixing it with water), Flos Caryophylli 3g, Fructus Amomi Rotundus 6g, Caulis Perillae 10g, Rhizoma Pinelliae 6g, Pericarpium Citri Reticulatae 6g, fresh ginger 10g, Massa Medicata Fermentata 10g, Endothelium corneum 10g, Radix Stemonae 10g, Bulbus Lilii 10g, Herba Schizonepetae 10g, Pseudobulbus Bletillae (Rhizoma Bletillae) 10g, Colla Corii Asini 10g, Radix Platycodonis 8g, Fructus Perillae 8g, Semen Lepidii 12g, Radix Glycyrrhizae 6g.
(2) YUNNAN BAIYAO 10g divides and takes after mixing it with water for three times.
Cause vomiting for preventing to take medicine, chew one of fresh ginger before taking medicine earlier, the soup of slowly taking medicine after 5 minutes.
December was examined in 14 days two, and three doses of prodrugs spitting of blood is ended, and vomiting stops, one bowl in the gruel of taking food, and YUNNAN BAIYAO is removed in medicine-feeding, adds with the anti-consumptive disease ball of compound recipe, 17 of every clothes, 2 times/day.
December was examined in 20 days three, and appetite is cumulative, and cough alleviates, and satisfied the decoction of stopping using, and only obeyed the multiple anti-consumptive disease ball of compound recipe, 31 of every clothes, 2 times/day.
On January 1st, 2000, can out-of-bed activity, symptom subtracts again, satisfies to change the multiple anti-consumptive disease ball consumption of compound recipe into 31 of every clothes, 3 times/day.
On April 15th, 2000, symptom disappears basically, the most of calcification of X-ray sheet focus, and fleshiness, life can be taken care of oneself, and continues to take the anti-consumptive disease ball of compound recipe two weeks to consolidate curative effect, follows up a case by regular visits to so far not recurrence.
Three of case: Li Dongli, the woman, 25 years old, the job-waiting youth lived Xi Wuqi, telephone number: 0479-3522619.
Readme is suffered from cough, night sweat, chest pain, is diagnosed as pulmonary tuberculosis through western Wu Qi hospital at the bottom of nineteen ninety-five, hospitalization two months, curative effect is not obvious, after successively use mongolian medicine, Western medicine, treatment by Chinese herbs in Xi Wuqi Mongolian medicine hospital, Linxi County hospital again; State of an illness day is heavy, forwards Chifeng City tuberculosis hospital again to, is diagnosed as pulmonary tuberculosis late period, fails to respond to any medical treatment; And send the notice of being critically ill, year in October, 2000 makes referrals to the Xilin Hot through other people and goes to a doctor, and according to aforementioned each hospital diagnosis result, satisfies and gives with the anti-consumptive disease ball of compound recipe; 31 of every clothes, 3 times/day, the back 30 days diet of taking medicine are cumulative; Each symptom day by day alleviates, and in May calendar year 2001, the X-ray sheet shows the complete calcification of focus; Expectorant inspection (one) is satisfied to accuse and is cured, and begin to do manual work to Huhehaote June calendar year 2001.
Four of case: Li Mei, the woman 78 years old, lives the Kulun Banner, Tongliao City, telephone number: 0475-4915313.May calendar year 2001, suffer from cough, chest pain, apoplexy due to phlegm have the blood streak, and it is surplus that hospital is diagnosed as miliary tuberculosis, the hospitalization moon through the Kulun Banner, and cough, chest pain increase the weight of, concurrent hepatalgia (being diagnosed as hepatic cyst), stomachache, vomiting, loss of appetite, fever.Then leave hospital and see a doctor.According to hospital diagnosis, give the clothes compound recipe anti-consumptive disease ball, 31 of every clothes, 2 times/day, and to hepatoprotective and the same clothes of stomachic.Medication was had a stomachache after one month, symptoms of emesis disappears, and satisfied the stomachic of stopping using, and continued to take the anti-consumptive disease ball of compound recipe, and instructions about how to take medicine are the same.Calendar year 2001, the December lung symptoms disappeared, and the X-ray sheet shows all calcifications of focus, expectorant inspection ().
Five of case: precious wooden Su Rong, woman, Meng ethnic group, 36 years old, the eastern Su Qi cadre of Administration of State Bureau, telephone number: 0479-2525991.Calendar year 2001 first visit on November 5, rickets is sent out in this patient dysplasia since the childhood in the time of 7 years old, fail to cure.The pulmonary tuberculosis that starts in 1993 fails to cure through chemotherapy all the time, to October calendar year 2001 at the Dong Suqi tuberculosis in late period that is diagnosed as hospitalized to have a thorough examination, bottom right lung lung atrophy, concurrent emphysema, pulmonary heart disease, heart failure II °.X-ray sheet podiod shows beaker shape, vertical diaphragm displacement, and costa sternales is parallel, intercostal space broadening, breather gas is forced, and is on the point of dying.School informs that the household hangs by a hair, and can't treat, and leaves hospital then and.November 5 calendar year 2001, its household was with above-mentioned diagnosis to come Xi Meng to see a doctor, and saw that its suction prolongs the lingering breath of life.To sum up state the complicated critical state of an illness, probably obey pill and be difficult to quick-actingly,, be decocted in water for oral dose so add and subtract with anti-consumptive disease ball side, every day potion.17 days two November of calendar year 2001 examines, and the place ahead 10 doses of all diseases of taking medicine subtract greatly, can get up.Its household comes stannum to ask medicine once more, still controls it with anti-consumptive disease ball plus-minus side.Calendar year 2001, December was examined in 1 day three, and prodrug is obeyed 10 doses again, and various symptoms greatly alleviate, and life can be taken care of oneself, and the Xi Shi that comes in person then sees a doctor, and still with anti-consumptive disease ball side plus-minus, administration is 10 doses again.The four diagnostic methods on January 31 in 2002, prodrug are various transference cures after 10 doses again, and drug withdrawal is after 20 days, because of Changes in weather feel again cardiopalmus, breathe hard, cough, examined once more January 31, still with 10 doses of anti-consumptive disease ball plus-minus administrations, all diseases in clothes back disappear, muscle is gradually rich.So far, should continue medication, in the hope of thorough healing.Do not have discomfort but it is thought, can not ask medicine in the Lai Xi city because of intemperance again, so a medication 40 days.Until on JIUYUE 8th, 2003 feel again breathe hard, uncomfortable in chest and examine, use what medicine during asking about again, claim its medicine after health feel uncomfortable always, once caught a cold 2 times during just, used coldrex, do not use other medicines again.
Six of case: Huo Chunguang, man, Han nationality, 20 years old; Postinfectious cough in 1997, chest pain, night sweat, Coritab is failed to respond to any medical treatment; Chest hospital is diagnosed as infiltrative pulmonary tuberculosis through the Inner Mongol, and chemotherapy is many half a year, and symptoms such as cough, chest pain disappear basically, but abdominal distention is suffered from abdominal pain in treatment; Inappetence, symptoms such as dull pain in liver day by day increase the weight of, and compelled drug withdrawal.Pulmonary tuberculosis several times recurs later on; To in November, 2000 state of an illness increase the weight of, hospital is diagnosed as pulmonary tuberculosis through the Shenzhen, still uses the treatment of medicines such as isoniazid, rifampicin, pyrazine acyl ammonia; Curative effect does not show; Come the Xilin Hot for buying the anti-consumptive disease ball of compound recipe in January, 2002 according to relatives Wang Yonghe (the positive retired cadre of Lan Qi water conservancy bureau), mail Shenzhen to, front and back are taken the anti-consumptive disease ball of compound recipe 1.6kg altogether away.Treat nearly one hundred days, instructions about how to take medicine, each 31 (crude drug 4.6kg) takes three every day, shows the whole calcifications of focus through the X-ray examination result, follows up a case by regular visits to so far not recurrence, and married and given birth to babies.
Seven of case: Li Dongmei, the woman 27 years old, lives Xi Wuqi, telephone number 0479-3522619.Suffer from cough, chest pain in the end of the year 1992 of patient's readme, be diagnosed as pulmonary tuberculosis through western Wu Qi hospital, hospitalization two months, curative effect does not show; After again in Xi Wuqi Mongolian medicine hospital, Linxi County hospital, woods east county hospital is successively used mongolian medicine, Western medicine, treatment by Chinese herbs; The state of an illness increases the weight of day by day, and Chifeng City tuberculosis hospital of transferring from one hospital to another again is diagnosed as the pulmonary tuberculosis in late period; Merge chronic nephritis, fail to respond to any medical treatment, and send and be critically ill notice and leave hospital.Make referrals to the Xilin Hot through other people and go to a doctor in October, 2000. according to aforementioned each hospital diagnosis result, give with the anti-consumptive disease ball of compound recipe.Instructions about how to take medicine: each 31 (being equivalent to crude drug 4.6kg), to take every day three times, the back month surplus appetite of taking medicine increases, and body constitution makes moderate progress, and symptom day by day alleviates, inspection in May calendar year 2001, all calcifications of pulmonary's TB focus are married at present.
Eight of case: Cai new people, man, 35 years old, the police of municipal public security bureau, Xilin Hot.Be diagnosed as infiltrative pulmonary tuberculosis from being set forth in 1998 through hospital of alliance of stannum alliance, bad during fashion after the chemotherapy, outbreak repeatedly, the state of an illness day by day increases the weight of; Chest pain, cough, apoplexy due to phlegm have the blood streak sometimes, have no appetite general weakness; Day by day become thin, and medicamentous liver lesion and gastrointestinal dysfunction symptom also are on the rise blood count ALT87u (Lai Shi); So other people introduced and examine in December in 2002 17 days, according to preceding addressing hospital diagnosis, satisfy and add with the anti-consumptive disease ball of compound recipe that dried feces of Sus scrofa L.-ten flavor looses and golden Fructus Chebulae-five tastes loose: to regulate hepatogastric function; Treat that sb.'s illness took a favorable turn after three months, the X-ray sheet shows the most of calcification of focus, continues again later on the anti-consumptive disease pill for curing of compound recipe 5 months; The X-ray sheet shows the whole calcifications of focus, and weight increase 6kg follows up a case by regular visits to so far not recurrence.
Nine of case: Ulan, woman, the Mongols, 19 years old; The east Wu Qi middle school student of the Mongols, catch a cold in May, 2002, cough; After with the Coritab treatment, cold symptoms disappears, and cough only is coughed, the chest pain a few days is more than; Fever in the afternoon, night sweat, eastern black flag examination in hospital is diagnosed as foxtail millet grain type pulmonary tuberculosis, eats mongolian medicine.Have an injection, more than 50 day state of an illness of infusion treatment do not felt any better, and seeks medical advice in the Xilin Hot of coming, and according to aforementioned diagnosis, with the anti-consumptive disease pill for curing of compound recipe two months, the X-ray sheet showed the complete calcification of focus, recurrence so far, and the Huhehaote of at present having transferred to another school to studies vocal music.
Ten of case: flower draws woman, 28 years old, the Mongols; The positive blue bannerman of Xi Meng finds to suffer from pulomonary hilar lymphoid tuberculosis in April, 2003 during health check-up before Lan Qi hospital goes abroad, see a doctor to the Xilin Hot; Give with the anti-consumptive disease pill for curing of compound recipe after two months, the X-ray sheet shows the whole calcifications of focus, has gone to Japan to study abroad at present.
Two, the another one technical problem of the present invention's solution is the method for preparing that works out above-mentioned tuberculosis medicine.Its preparation method is: Herba Potentillae Discoloris, Radix Glycyrrhizae, Spica Prunellae, Herba Schizonepetae, Folium Ilicis Cornutae, the Radix Stemonae, the Folium Artemisiae Argyi assistant of getting recipe quantity are broken with section, measure soak with ethanol 2 hours with 10 times, reflux 1.5 hours; 10 times of medicinal residues reuse 60% ethanol amount refluxed 1.5 hours, collected backflow, reclaimed ethanol and was concentrated into the thick paste of relative density 1.30～1.35 (60 ℃); Above medicinal residues and Rhizoma Polygonati, Radix Codonopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) add 10 times of water gagings and decoct 2 times, and each 1 hour, it was subsequent use to be concentrated into relative density 1.25～1.30 (80 ℃) thick paste; Ovum Gallus domesticus crusta superfine powder in the prescription is broken into fine powder and adds the water boiling concentration thick paste and merge dryly, adds Colla cornus cervi, Colla Corii Asini powder coarse powder and alcohol after the pulverizing again and concentrates thick paste, and is dry below 75 ℃, pulverize, cross 80 mesh sieves and process.
The specific embodiment
Embodiment 1:
Prescription: Herba Potentillae Discoloris 20g Rhizoma Polygonati 50g Radix Codonopsis 50g Colla Corii Asini 10g Colla cornus cervi 10g
Spica Prunellae 50g Herba Schizonepetae 50g Folium Ilicis Cornutae 30g Pseudobulbus Bletillae (Rhizoma Bletillae) 50g Radix Stemonae 50g
Folium Artemisiae Argyi 50g Ovum Gallus domesticus crusta 20g Radix Glycyrrhizae 10g
Preparation: Herba Potentillae Discoloris, Radix Glycyrrhizae, Spica Prunellae, Herba Schizonepetae, Folium Ilicis Cornutae, the Radix Stemonae, the Folium Artemisiae Argyi assistant of getting recipe quantity are broken with section, measure soak with ethanol 2 hours with 10 times, reflux 1.5 hours; 10 times of amounts of medicinal residues reuse 60% ethanol refluxed 1.5 hours; Collect backflow; Reclaim ethanol and be concentrated into the thick paste of relative density 1.30～1.35 (60 ℃); Above medicinal residues and Rhizoma Polygonati, Radix Codonopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) add 10 times of water gagings and decoct 2 times, and each 1 hour, it was subsequent use to be concentrated into relative density 1.25～1.30 (80 ℃) thick paste; Ovum Gallus domesticus crusta superfine powder in the prescription is broken into fine powder and adds the water boiling concentration thick paste and merge dryly, adds Colla cornus cervi, Colla Corii Asini powder coarse powder and alcohol after the pulverizing again and concentrates thick paste, and is dry below 75 ℃, pulverize, cross 80 mesh sieves and process.
Embodiment 2:
Prescription: Herba Potentillae Discoloris 30g Rhizoma Polygonati 60g Radix Codonopsis 60g Colla Corii Asini 20g Colla cornus cervi 20g
Spica Prunellae 60g Herba Schizonepetae 60g Folium Ilicis Cornutae 40g Pseudobulbus Bletillae (Rhizoma Bletillae) 50g Radix Stemonae 50g
Folium Artemisiae Argyi 60g Ovum Gallus domesticus crusta 30g Radix Glycyrrhizae 20g
Preparation: Herba Potentillae Discoloris, Radix Glycyrrhizae, Spica Prunellae, Herba Schizonepetae, Folium Ilicis Cornutae, the Radix Stemonae, the Folium Artemisiae Argyi assistant of getting recipe quantity are broken with section, measure soak with ethanol 3 hours with 9 times, reflux 1 hour; 10 times of amounts of medicinal residues reuse 60% ethanol refluxed 1.5 hours; Collect backflow; Reclaim ethanol and be concentrated into the thick paste of relative density 1.30～1.35 (60 ℃); Above medicinal residues and Rhizoma Polygonati, Radix Codonopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) add 10 times of water gagings and decoct 2 times, and each 1.5 hours, it was subsequent use to be concentrated into relative density 1.25～1.30 (80 ℃) thick paste; Ovum Gallus domesticus crusta superfine powder in the prescription is broken into fine powder and adds the water boiling concentration thick paste and merge dryly, adds Colla cornus cervi, Colla Corii Asini powder coarse powder and alcohol after the pulverizing again and concentrates thick paste, and is dry below 80 ℃, pulverize, cross 80 mesh sieve systems.
Embodiment 3:
Prescription: Herba Potentillae Discoloris 40g Rhizoma Polygonati 70g Radix Codonopsis 70g Colla Corii Asini 30g Colla cornus cervi 30g
Spica Prunellae 70g Herba Schizonepetae 60g Folium Ilicis Cornutae 50g Pseudobulbus Bletillae (Rhizoma Bletillae) 70g Radix Stemonae 60g
Folium Artemisiae Argyi 50g Ovum Gallus domesticus crusta 40g Radix Glycyrrhizae 30g
Preparation: with embodiment 2.
Embodiment 4:
Prescription: Herba Potentillae Discoloris 50g Rhizoma Polygonati 80g Radix Codonopsis 80g Colla Corii Asini 40g Colla cornus cervi 40g
Spica Prunellae 80g Herba Schizonepetae 70g Folium Ilicis Cornutae 60g Pseudobulbus Bletillae (Rhizoma Bletillae) 80g Radix Stemonae 70g
Folium Artemisiae Argyi 60g Ovum Gallus domesticus crusta 50g Radix Glycyrrhizae 40g
Preparation: with embodiment 2.
Embodiment 5:
Prescription: Herba Potentillae Discoloris 60g Rhizoma Polygonati 90g Radix Codonopsis 90g Colla Corii Asini 50g Colla cornus cervi 50g
Spica Prunellae 90g Herba Schizonepetae 80g Folium Ilicis Cornutae 70g Pseudobulbus Bletillae (Rhizoma Bletillae) 90g Radix Stemonae 80g
Folium Artemisiae Argyi 70g Ovum Gallus domesticus crusta 60g Radix Glycyrrhizae 50g
Preparation: with embodiment 2.
Embodiment 6:
Prescription: Herba Potentillae Discoloris 60g Rhizoma Polygonati 120g Radix Codonopsis 120g Colla Corii Asini 30g Colla cornus cervi 30g
Spica Prunellae 120g Herba Schizonepetae 120g Folium Ilicis Cornutae 90g Pseudobulbus Bletillae (Rhizoma Bletillae) 120g Radix Stemonae 120g
Folium Artemisiae Argyi 120g Ovum Gallus domesticus crusta 90g Radix Glycyrrhizae 30g
Preparation: Herba Potentillae Discoloris, Radix Glycyrrhizae, Spica Prunellae, Herba Schizonepetae, Folium Ilicis Cornutae, the Radix Stemonae, the Folium Artemisiae Argyi assistant of getting recipe quantity are broken with section, measure soak with ethanol 3 hours with 9 times, reflux 1 hour; 10 times of amounts of medicinal residues reuse 60% ethanol refluxed 1.5 hours; Collect backflow; Reclaim ethanol and be concentrated into the thick paste of relative density 1.30～1.35 (60 ℃); Above medicinal residues and Rhizoma Polygonati, Radix Codonopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) add 10 times of water gagings and decoct 2 times, and each 1.5 hours, it was subsequent use to be concentrated into relative density 1.25～1.30 (80 ℃) thick paste; Ovum Gallus domesticus crusta superfine powder in the prescription is broken into fine powder and adds the water boiling concentration thick paste and merge dryly, adds Colla cornus cervi, Colla Corii Asini powder coarse powder and alcohol after the pulverizing again and concentrates thick paste, and is dry below 80 ℃, pulverize, cross 80 mesh sieve systems.
Embodiment 7:
Prescription: Herba Potentillae Discoloris 70g Rhizoma Polygonati 80g Radix Codonopsis 90g Colla Corii Asini 30g Colla cornus cervi 20g
Spica Prunellae 80g Herba Schizonepetae 80g Folium Ilicis Cornutae 70g Pseudobulbus Bletillae (Rhizoma Bletillae) 80g Radix Stemonae 70g
Folium Artemisiae Argyi 80g Ovum Gallus domesticus crusta 50g Radix Glycyrrhizae 30g
Preparation: with embodiment 6.
Embodiment 8:
Prescription: Herba Potentillae Discoloris 80g Rhizoma Polygonati 90g Radix Codonopsis 100g Colla Corii Asini 30g Colla cornus cervi 30g
Spica Prunellae 110g Herba Schizonepetae 120g Folium Ilicis Cornutae 80g Pseudobulbus Bletillae (Rhizoma Bletillae) 100g Radix Stemonae 120g
Folium Artemisiae Argyi 110g Ovum Gallus domesticus crusta 50g Radix Glycyrrhizae 30g
Preparation: with embodiment 6.
Embodiment 9:
Prescription: Herba Potentillae Discoloris 80g Rhizoma Polygonati 120g Radix Codonopsis 110g Colla Corii Asini 30g Colla cornus cervi 40g
The white 120g Radix Stemonae of Spica Prunellae 100g Herba Schizonepetae 120g Folium Ilicis Cornutae 100g 100g
Folium Artemisiae Argyi 120g Ovum Gallus domesticus crusta 60g Radix Glycyrrhizae 40g
Preparation: with embodiment 6.
Claims (3)
1. treat phthisical mongolian medicine for one kind, it is characterized in that it is the preparation of being processed by the following weight proportion raw material:
2. mongolian medicine according to claim 1 is characterized in that this mongolian medicine can be made into the solid preparation that comprises granule, tablet, capsule or pill.
3. the method for preparing of the said mongolian medicine of claim 1; It is characterized in that; May further comprise the steps: Herba Potentillae Discoloris, Radix Glycyrrhizae, Spica Prunellae, Herba Schizonepetae, Folium Ilicis Cornutae, the Radix Stemonae, the Folium Artemisiae Argyi assistant of getting said weight proportion are broken with section, measure soak with ethanol 2 hours with 10 times, reflux 1.5 hours; 10 times of amounts of medicinal residues reuse 60% ethanol refluxed 1.5 hours, collected backflow, and relative density is 1.30～1.35 thick paste when reclaiming ethanol and being concentrated into 60 ℃; Above medicinal residues and Rhizoma Polygonati, Radix Codonopsis, Pseudobulbus Bletillae (Rhizoma Bletillae) add 10 times of water gagings and decoct 2 times, and each 1 hour, relative density was that 1.25～1.30 thick paste is subsequent use when being concentrated into 80 ℃; The Ovum Gallus domesticus crusta superfine powder is broken into fine powder and adds the water boiling concentration thick paste and merge dryly, adds Colla cornus cervi, Colla Corii Asini powder coarse powder and alcohol after the pulverizing again and concentrates thick paste, and is dry below 75 ℃, pulverize, cross 80 mesh sieves and process preparation.
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