CN101518635A - Traditional Chinese medicine for treating gynecological inflammation, capable of removing heat and drying damp, activating blood and dissolving stasis - Google Patents

Traditional Chinese medicine for treating gynecological inflammation, capable of removing heat and drying damp, activating blood and dissolving stasis Download PDF

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Publication number
CN101518635A
CN101518635A CN200810101163A CN200810101163A CN101518635A CN 101518635 A CN101518635 A CN 101518635A CN 200810101163 A CN200810101163 A CN 200810101163A CN 200810101163 A CN200810101163 A CN 200810101163A CN 101518635 A CN101518635 A CN 101518635A
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parts
rhizoma
chinese medicine
clear paste
gynecological inflammation
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CN200810101163A
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吴士彬
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BEIJING ZHONGTAI TIANHE SCIENCE AND TECHNOLOGY Co Ltd
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BEIJING ZHONGTAI TIANHE SCIENCE AND TECHNOLOGY Co Ltd
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Abstract

The invention discloses a traditional Chinese medicine for treating gynecological inflammation, which is capable of removing heat and drying damp, activating blood and dissolving stasis; the traditional Chinese medicine consists of active components and/or carriers which are acceptable pharmaceutically, wherein the active components are extracted and prepared from the following raw materials: chinaberry fruits, processed rhizome of corydalis, sophora flavescens, caulis lonicerae, angelica, radices curcumae zedoariae, rhizoma smilacis glabrae, semen coicis, radices salviae miltiorrhizae, rhizoma atractylodis, rhizoma ligustici wallichii, rhizoma alismatis, perfoliate knotweed herb, cortex phellodendri and the like. The traditional Chinese medicine is capable of removing heat and drying damp, activating blood and dissolving stasis, thus being used for treating cervicitis, colpitis, irregular menstruation, leukorrhea with reddish discharge, appendagitis and the like. The invention also discloses a preparation method of the traditional Chinese medicine.

Description

A kind of heat clearing and damp drying, blood circulation promoting and blood stasis dispelling are used for the Chinese medicine of gynecological inflammation
Technical field:
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to the Chinese medicine that a kind of heat clearing and damp drying, blood circulation promoting and blood stasis dispelling are used for gynecological inflammation, the invention still further relates to this preparation method of Chinese medicine.
Technical background
The most common in the gynecological inflammation with vaginitis, cervicitis, pelvic inflammatory disease.Wherein, cervicitis sickness rate in married women is the highest, often shows as cervical erosion, and cervical erosion is as can not in time finding, reaching early treatment, and hatefulness turns to cervical cancer.And symptoms such as the women who suffers from pelvic inflammatory disease has low grade fever, lassitude, the whole body is uncomfortable, hypogastric region weighs down and expands, pain and menoxenia, as untimely treatment, tend to become chronic pelvic inflammatory disease from acute pelvic inflammatory disease, cause infertile, cause the women repent forever, " sunlight " expert reminds especially: because the female pathology structure, it is concurrent that a kind of inflammation tends to cause multiple inflammation! Therefore, female friends must not adopt a casual attitude to inflammation, and answer active treatment with trouble without offspring.
The especially married women of women usually can be subjected to the invasion of gynecological inflammation; according to World Health Organization (WHO) China women's a investigation is shown: in China women at reproduction age; about 41% women suffers from gynecological inflammation disease in various degree, and married women's sickness rate is more so high up to 70%. gynecological inflammation sickness rate.
The present invention is selected from folk remedy, in conjunction with the modern Chinese medicine pharmaceutical technology, is made into multiple dosage form, makes things convenient for the patient to carry and takes, and further satisfies and ensured people's medication demand.
Efficacy component of the present invention has heat clearing and damp drying, blood circulation promoting and blood stasis dispelling.Be used for cervicitis, vaginitis, menoxenia, leucorrhea with red and white discharge, dysmenorrhea, adnexitis etc.
Summary of the invention:
One of purpose of the present invention provides the Chinese medicine that a kind of heat clearing and damp drying, blood circulation promoting and blood stasis dispelling are used for gynecological inflammation.
Another purpose of the present invention provides this preparation method of Chinese medicine.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
110-330 parts of 130-390 parts of Radix Sophorae Flavescentiss of 130-390 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
130-390 parts of 130-390 parts of Rhizoma Curcumae of 110-330 parts of Radix Angelicae Sinensis of Caulis Lonicerae
110-330 parts of 130-390 parts of Radix Salviae Miltiorrhizaes of 110-330 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
110-330 parts of 80-240 parts of Rhizoma Alismatis of 80-240 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
110-330 parts of 80-240 parts of Cortex Phellodendris of Herba Polygoni cymosi
The active component that preferred following raw materials according is made, curative effect is better:
150 parts of 200 parts of Radix Sophorae Flavescentiss of 200 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
200 parts of 200 parts of Rhizoma Curcumae of 150 parts of Radix Angelicae Sinensis of Caulis Lonicerae
150 parts of 200 parts of Radix Salviae Miltiorrhizaes of 150 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
150 parts of 120 portions of Rhizoma Alismatis of 120 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
150 parts of 120 portions of Cortex Phellodendris of Herba Polygoni cymosi
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
Preparation technology:
(1) get Rhizoma Corydalis (processed) with 80% alcohol reflux 2 times, 2 hours for the first time, filtered in 1 hour for the second time, filtrate recycling ethanol, clear paste is standby;
(2) getting Fructus Toosendan, Radix Sophorae Flavescentis, Caulis Lonicerae, Radix Angelicae Sinensis, Rhizoma Curcumae, Rhizoma Smilacis Glabrae, Semen Coicis, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Rhizoma Chuanxiong, Rhizoma Alismatis, Herba Polygoni cymosi, Cortex Phellodendri adds 10 times of water gagings and decocts 2 times, 2 hours for the first time, 1 hour for the second time, filter merging filtrate, be condensed into clear paste, in clear paste, add ethanol and make the alcohol amount of containing reach 70% (V/V), cold preservation 12 hours, filter the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature at 60-75 ℃ be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) clear paste such as Rhizoma Corydalis (processed) clear paste and Fructus Toosendan, Radix Sophorae Flavescentis are merged, both be ground into dry powder behind stirring and evenly mixing, the vacuum drying.
Effective ingredient of the present invention can be prepared into oral formulations such as granule, tablet, capsule with acceptable accessories.
The effective ingredient of drug regimen of the present invention has heat clearing and damp drying, blood circulation promoting and blood stasis dispelling.Be used for cervicitis, vaginitis, menoxenia, leucorrhea with red and white discharge, dysmenorrhea, adnexitis etc.
The specific embodiment
Embodiment 1: the preparation of granule
1, prescription
150 parts of 200 parts of Radix Sophorae Flavescentiss of 200 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
200 parts of 200 parts of Rhizoma Curcumae of 150 parts of Radix Angelicae Sinensis of Caulis Lonicerae
150 parts of 200 parts of Radix Salviae Miltiorrhizaes of 150 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
150 parts of 120 portions of Rhizoma Alismatis of 120 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
150 parts of 120 portions of Cortex Phellodendris of Herba Polygoni cymosi
2, preparation technology
(1) get Rhizoma Corydalis (processed) with 80% alcohol reflux 2 times, 2 hours for the first time, filtered in 1 hour for the second time, filtrate recycling ethanol, clear paste is standby;
(2) getting Fructus Toosendan, Radix Sophorae Flavescentis, Caulis Lonicerae, Radix Angelicae Sinensis, Rhizoma Curcumae, Rhizoma Smilacis Glabrae, Semen Coicis, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Rhizoma Chuanxiong, Rhizoma Alismatis, Herba Polygoni cymosi, Cortex Phellodendri adds 10 times of water gagings and decocts 2 times, 2 hours for the first time, 1 hour for the second time, filter merging filtrate, be condensed into clear paste, in clear paste, add ethanol and make the alcohol amount of containing reach 70% (V/V), cold preservation 12 hours, filter the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature at 60-75 ℃ be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) clear paste such as Rhizoma Corydalis (processed) clear paste and Fructus Toosendan, Radix Sophorae Flavescentis are merged, be ground into dry powder behind stirring and evenly mixing, the vacuum drying and add right amount of auxiliary materials again, mixing is granulated, promptly.
Embodiment 2: the preparation of tablet
1, prescription:
150 parts of 200 parts of Radix Sophorae Flavescentiss of 200 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
200 parts of 200 parts of Rhizoma Curcumae of 150 parts of Radix Angelicae Sinensis of Caulis Lonicerae
150 parts of 200 parts of Radix Salviae Miltiorrhizaes of 150 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
150 parts of 120 portions of Rhizoma Alismatis of 120 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
150 parts of 120 portions of Cortex Phellodendris of Herba Polygoni cymosi
2, preparation technology:
(1) Rhizoma Corydalis (processed) is with 80% alcohol reflux 2 times, and 2 hours for the first time, filtered in 1 hour for the second time, filtrate recycling ethanol, clear paste is standby;
(2) getting Fructus Toosendan, Radix Sophorae Flavescentis, Caulis Lonicerae, Radix Angelicae Sinensis, Rhizoma Curcumae, Rhizoma Smilacis Glabrae, Semen Coicis, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Rhizoma Chuanxiong, Rhizoma Alismatis, Herba Polygoni cymosi, Cortex Phellodendri adds 10 times of water gagings and decocts 2 times, 2 hours for the first time, 1 hour for the second time, filter merging filtrate, be condensed into clear paste, in clear paste, add ethanol and make the alcohol amount of containing reach 70% (V/V), cold preservation 12 hours, filter the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature at 60-75 ℃ be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) clear paste such as Rhizoma Corydalis (processed) clear paste and Fructus Toosendan, Radix Sophorae Flavescentis are merged, be ground into dry powder behind stirring and evenly mixing, the vacuum drying and add right amount of auxiliary materials again, mixing is granulated, compacting in flakes, promptly.
Embodiment 3: the preparation of capsule
1, prescription
150 parts of 200 parts of Radix Sophorae Flavescentiss of 200 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
200 parts of 200 parts of Rhizoma Curcumae of 150 parts of Radix Angelicae Sinensis of Caulis Lonicerae
150 parts of 200 parts of Radix Salviae Miltiorrhizaes of 150 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
150 parts of 120 portions of Rhizoma Alismatis of 120 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
150 parts of 120 portions of Cortex Phellodendris of Herba Polygoni cymosi
2, preparation technology:
(1) get Rhizoma Corydalis (processed) with 80% alcohol reflux 2 times, 2 hours for the first time, filtered in 1 hour for the second time, filtrate recycling ethanol, clear paste is standby;
(2) getting Fructus Toosendan, Radix Sophorae Flavescentis, Caulis Lonicerae, Radix Angelicae Sinensis, Rhizoma Curcumae, Rhizoma Smilacis Glabrae, Semen Coicis, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Rhizoma Chuanxiong, Rhizoma Alismatis, Herba Polygoni cymosi, Cortex Phellodendri adds 10 times of water gagings and decocts 2 times, 2 hours for the first time, 1 hour for the second time, filter merging filtrate, be condensed into clear paste, in clear paste, add ethanol and make the alcohol amount of containing reach 70% (V/V), cold preservation 12 hours, filter the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature at 60-75 ℃ be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) clear paste such as Rhizoma Corydalis (processed) clear paste and Fructus Toosendan, Radix Sophorae Flavescentis are merged, be ground into dry powder behind stirring and evenly mixing, the vacuum drying and add right amount of auxiliary materials again, mixing is granulated, and is encapsulated, promptly.

Claims (5)

1, a kind of heat clearing and damp drying, blood circulation promoting and blood stasis dispelling are used for the Chinese medicine of gynecological inflammation, it is characterized in that by active ingredient and/or pharmaceutically acceptable
Carrier form, wherein said active ingredient is made by following raw materials according:
110-330 parts of 130-390 parts of Radix Sophorae Flavescentiss of 130-390 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
130-390 parts of 130-390 parts of Rhizoma Curcumae of 110-330 parts of Radix Angelicae Sinensis of Caulis Lonicerae
110-330 parts of 130-390 parts of Radix Salviae Miltiorrhizaes of 110-330 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
110-330 parts of 80-240 parts of Rhizoma Alismatis of 80-240 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
110-330 parts of 80-240 parts of Cortex Phellodendris of Herba Polygoni cymosi.
2, a kind of heat clearing and damp drying according to claim 1, blood circulation promoting and blood stasis dispelling are used for the Chinese medicine of gynecological inflammation, it is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
150 parts of 200 parts of Radix Sophorae Flavescentiss of 200 parts of Rhizoma Corydalis (processed)s of Fructus Toosendan
200 parts of 200 parts of Rhizoma Curcumae of 150 parts of Radix Angelicae Sinensis of Caulis Lonicerae
150 parts of 200 parts of Radix Salviae Miltiorrhizaes of 150 parts of Semen Coiciss of Rhizoma Smilacis Glabrae
150 parts of 120 portions of Rhizoma Alismatis of 120 parts of Rhizoma Chuanxiongs of Rhizoma Atractylodis
150 parts of 120 portions of Cortex Phellodendris of Herba Polygoni cymosi.
3, be used for the Chinese medicine of gynecological inflammation according to the described a kind of heat clearing and damp drying of claim 1-2, blood circulation promoting and blood stasis dispelling, it is characterized in that adopting following method to make:
(1) get Rhizoma Corydalis (processed) with 80% alcohol reflux 2 times, 2 hours for the first time, filtered in 1 hour for the second time, filtrate recycling ethanol, clear paste is standby;
(2) getting Fructus Toosendan, Radix Sophorae Flavescentis, Caulis Lonicerae, Radix Angelicae Sinensis, Rhizoma Curcumae, Rhizoma Smilacis Glabrae, Semen Coicis, Radix Salviae Miltiorrhizae, Rhizoma Atractylodis, Rhizoma Chuanxiong, Rhizoma Alismatis, Herba Polygoni cymosi, Cortex Phellodendri adds 10 times of water gagings and decocts 2 times, 2 hours for the first time, 1 hour for the second time, filter merging filtrate, be condensed into clear paste, in clear paste, add ethanol and make the alcohol amount of containing reach 70% (V/V), cold preservation 12 hours, filter the filtered solution decompression recycling ethanol; To be concentrated into relative density under the temperature at 60-75 ℃ be 1.12-1.20 clear paste with reclaiming concentrated solution behind the ethanol;
(3) clear paste such as Rhizoma Corydalis (processed) clear paste and Fructus Toosendan, Radix Sophorae Flavescentis are merged, both be ground into dry powder behind stirring and evenly mixing, the vacuum drying.
4, be used for the Chinese medicine of gynecological inflammation according to any one described a kind of heat clearing and damp drying, blood circulation promoting and blood stasis dispelling among the claim 1-3, it is characterized in that being oral formulations.
5, be used for the Chinese medicine of gynecological inflammation according to the described a kind of heat clearing and damp drying of claim 5, blood circulation promoting and blood stasis dispelling, it is characterized in that granule, capsule, tablet.
CN200810101163A 2008-02-28 2008-02-28 Traditional Chinese medicine for treating gynecological inflammation, capable of removing heat and drying damp, activating blood and dissolving stasis Pending CN101518635A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526399A (en) * 2012-02-02 2012-07-04 李坤 Chinese medicine preparation for treating chronic pelvic inflammation
CN103536840A (en) * 2013-11-05 2014-01-29 孙丽 Traditional Chinese medicine for treating leukorrheal diseases of syndrome of phlegm and blood stasis
CN104740528A (en) * 2015-03-06 2015-07-01 河南中医学院 Traditional Chinese medicine powder for treating cervicitis
CN106620075A (en) * 2016-12-23 2017-05-10 深圳市佳泰药业股份有限公司 Preparation method of drug for treating gynecologic inflammation
CN106728542A (en) * 2016-12-23 2017-05-31 深圳市佳泰药业股份有限公司 Treat the medicine of gynaecological imflammation

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102526399A (en) * 2012-02-02 2012-07-04 李坤 Chinese medicine preparation for treating chronic pelvic inflammation
CN102526399B (en) * 2012-02-02 2013-10-16 李坤 Chinese medicine preparation for treating chronic pelvic inflammation
CN103536840A (en) * 2013-11-05 2014-01-29 孙丽 Traditional Chinese medicine for treating leukorrheal diseases of syndrome of phlegm and blood stasis
CN103536840B (en) * 2013-11-05 2015-07-29 青岛市海慈医疗集团 A kind of Chinese medicine for the treatment of phlegm and blood stasis pattern of syndrome leukorrheal diseases
CN104740528A (en) * 2015-03-06 2015-07-01 河南中医学院 Traditional Chinese medicine powder for treating cervicitis
CN104740528B (en) * 2015-03-06 2018-06-26 河南中医学院 A kind of traditional Chinese medicine powder for treating cervicitis
CN106620075A (en) * 2016-12-23 2017-05-10 深圳市佳泰药业股份有限公司 Preparation method of drug for treating gynecologic inflammation
CN106728542A (en) * 2016-12-23 2017-05-31 深圳市佳泰药业股份有限公司 Treat the medicine of gynaecological imflammation

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Open date: 20090902