CN101396548B - Medicine composition for treating chronic gastritis - Google Patents

Medicine composition for treating chronic gastritis Download PDF

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Publication number
CN101396548B
CN101396548B CN2007101755390A CN200710175539A CN101396548B CN 101396548 B CN101396548 B CN 101396548B CN 2007101755390 A CN2007101755390 A CN 2007101755390A CN 200710175539 A CN200710175539 A CN 200710175539A CN 101396548 B CN101396548 B CN 101396548B
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weight portion
radix
weight
rhizoma
pharmaceutical composition
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CN101396548A (en
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杨勤
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Abstract

The invention discloses a pharmaceutical composition for treating gastritis and gastric cancer, and the pharmaceutical composition is composed of pharmaceutical raw materials of membranous milk vetch root, radix rehmanniae preparata, to the maximum extent, common yam rhizome, white paeony root, tree peony bark, cassia twig, Indian buead, Chinese date, cassia bark, prepared common monkshood daughter root, barbary wolfberry fruit, oriental waterplantain rhizome, liquoric root, largehead atractylodes rhizome, dried ginger and common macrocarpium fruit. The pharmaceutical composition has significant efficacy on treating the chronic gastritis without any side effects.

Description

A kind of pharmaceutical composition for the treatment of chronic gastritis
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of pharmaceutical composition for the treatment of chronic gastritis.
Background technology
Chronic gastritis is the chronic inflammatory disease of the gastric mucosa that caused by the multiple different causes of disease.After its essence is that gastric epithelial is subjected to damaging repeatedly, because the special regeneration capacity of mucosa, so that mucosa reconstructs, and finally causes the atrophy of irreversible intrinsic gastric gland body, even disappearance, is a kind of commonly encountered diseases and frequently-occurring disease clinically.Chronic gastritis is divided three kinds of shallow, atrophic and plumpnesses, sees with atrophic more.Chronic gastritis is lacked the medicine of produce effects at present, is symptomatic treatment both at home and abroad basically, though Western medicine more on probation in recent years and Chinese medicine, its unsatisfactory curative effect.
Summary of the invention
The object of the invention is to provide a kind of pharmaceutical composition for the treatment of chronic gastritis.
The present invention is achieved through the following technical solutions:
The crude drug of pharmaceutical composition of the present invention consists of:
Radix Astragali 50-180 weight portion Radix Rehmanniae Preparata 5-15 weight portion Radix Codonopsis 30-100 weight portion
Rhizoma Dioscoreae 20-60 weight portion Radix Paeoniae Alba 5-15 weight portion Cortex Moutan 5-15 weight portion
Ramulus Cinnamomi 3-9 weight portion Poria 7-23 weight portion Fructus Jujubae 3-9 weight portion
Cortex Cinnamomi 7-23 weight portion Radix Aconiti Lateralis Preparata 7-23 weight portion Fructus Lycii 15-45 weight portion
Rhizoma Alismatis 3-9 weight portion Radix Glycyrrhizae 5-15 weight portion Rhizoma Atractylodis Macrocephalae 7-23 weight portion
Rhizoma Zingiberis 5-15 weight portion Fructus Corni 15-45 weight portion.
The crude drug of pharmaceutical composition of the present invention is preferably:
The Radix Astragali 115 weight portion Radix Rehmanniaes Preparata 10 weight portion Radix Codonopsis 60 weight portions
The Rhizoma Dioscoreae 40 weight portion Radix Paeoniae Albas 10 weight portion Cortex Moutans 10 weight portions
Ramulus Cinnamomi 6 weight portion Poria 15 weight portion Fructus Jujubaes 6 weight portions
Cortex Cinnamomi 15 weight portion Radix Aconiti Lateralis Preparatas 15 weight portion Fructus Lyciis 30 weight portions
The Rhizoma Alismatis 6 weight portion Radix Glycyrrhizaes 10 weight portion Rhizoma Atractylodis Macrocephalaes 15 weight portions
Rhizoma Zingiberis 10 weight portion Fructus Corni 30 weight portions.
The crude drug of pharmaceutical composition of the present invention is preferably:
The Radix Astragali 170 weight portion Radix Rehmanniaes Preparata 6 weight portion Radix Codonopsis 90 weight portions
The Rhizoma Dioscoreae 25 weight portion Radix Paeoniae Albas 14 weight portion Cortex Moutans 6 weight portions
Ramulus Cinnamomi 8 weight portion Poria 8 weight portion Fructus Jujubaes 8 weight portions
Cortex Cinnamomi 8 weight portion Radix Aconiti Lateralis Preparatas 20 weight portion Fructus Lyciis 20 weight portions
The Rhizoma Alismatis 8 weight portion Radix Glycyrrhizaes 6 weight portion Rhizoma Atractylodis Macrocephalaes 20 weight portions
Rhizoma Zingiberis 6 weight portion Fructus Corni 40 weight portions.
The crude drug of pharmaceutical composition of the present invention is preferably:
The Radix Astragali 70 weight portion Radix Rehmanniaes Preparata 14 weight portion Radix Codonopsis 40 weight portions
The Rhizoma Dioscoreae 50 weight portion Radix Paeoniae Albas 6 weight portion Cortex Moutans 14 weight portions
Ramulus Cinnamomi 4 weight portion Poria 20 weight portion Fructus Jujubaes 5 weight portions
Cortex Cinnamomi 20 weight portion Radix Aconiti Lateralis Preparatas 8 weight portion Fructus Lyciis 40 weight portions
The Rhizoma Alismatis 4 weight portion Radix Glycyrrhizaes 14 weight portion Rhizoma Atractylodis Macrocephalaes 8 weight portions
Rhizoma Zingiberis 14 weight portion Fructus Corni 20 weight portions.
Wherein, the described Radix Astragali is preferably Radix Astragali Preparata, and the Rhizoma Atractylodis Macrocephalae is preferably Rhizoma Atractylodis Macrocephalae (parched).
The conventional adjuvant that pharmaceutical composition of the present invention adds is pharmaceutically made clinical acceptable forms, as decoction, pill, powder, tablet, oral liquid, capsule or granule.
Pharmaceutical composition of the present invention has rapid healing, recovers fast, and the advantage that expense is lower has significant curative effect to treatment atrophic gastritis, superficial gastritis.
Following experimental example and embodiment are used to further specify the present invention:
Clinical treatment atrophic gastritis of the present invention, superficial gastritis disease 30 examples obtain promising result, now are reported as follows:
1, clinical data
30 examples are all through provincial hospital and the diagnosis of County Hospital gastroscope, wherein male 12 examples, women 18 examples; The oldest 72 years old, minimum 20 years old; The course of disease had 5 examples in the longest 12 years, and 2 examples were arranged in the shortest 1 year; Atrophic gastritis 19 examples, superficial gastritis 5 examples, intestinal moderate 6 examples.
2, Therapeutic Method
Medicine is formed: Radix Astragali 115g, Radix Rehmanniae Preparata 10g, Radix Codonopsis 60g, Rhizoma Dioscoreae 40g, Radix Paeoniae Alba 10g, Cortex Moutan 10g, Ramulus Cinnamomi 6g, Poria 15 g, Fructus Jujubae 6g, Cortex Cinnamomi 15g, Radix Aconiti Lateralis Preparata 15g, Fructus Lycii 30g, Rhizoma Alismatis 6g, Radix Glycyrrhizae 10g, Rhizoma Atractylodis Macrocephalae 15g, Rhizoma Zingiberis 10g, Fructus Corni 30g;
Preparation method: technology is made pill routinely, every 9g;
Instructions of taking: use warm boiled water, service once every day sooner or later ante cibum, and each 1,3 of serious symptoms.
3, therapeutic outcome
Among the above-mentioned 30 routine patients, produce effects 28 examples account for 94%, and effective 1 example accounts for 3.00%, and invalid 1 example accounts for 3.00%; Total effective rate 97%;
4, model case
Case 1: Zhao * *, woman, 27 years old, Lintao County Pan Jiaji township, Gansu Province Dan Jiashan people from group.1991 are invalid through multi-treatment through Lintao County hospital gastroscope inspection trouble atrophic gastritis, after kith and kin introduce the here treatment, take bolus of drug of the present invention, every 9g, and service once every day sooner or later ante cibum, obeys 1 at every turn.Patient fully recovered in two months, visited in recent years, and existing patient body health does not have recurrence.
Case 2: Du *, the man, 40 years old, Lintao County Xi Ping township Liu Jiawan people from village, this patient second half year in 1992 is because stomachache is diagnosed as the moderate atrophic gastritis to the gastroscopy of the People's Hospital, Gansu Province incessantly, it is also invalid to drink multiple stomach medicine, here treatment is afterwards taken bolus of drug of the present invention, every 9g, sooner or later service once every day ante cibum, and first week was obeyed 3 at every turn.Obey 1 subsequently, recovery from illness in three months is followed up a case by regular visits to and is not had recurrence at every turn.
Case 3: open * *, the man, 50 years old, Lintao County Xi Ping township Zhang Jiaping people from village, this patient is diagnosed as superficial atrophic gastritis through the Lintao County hospital gastroscope.Through multi-treatment invalid here afterwards treatment, take medicament capsule of the present invention, recovery from illness in three months is followed up a case by regular visits to and is not had recurrence.
Case 4: poplar *, the man, 46 years old, Lintao County Xi Ping township Yang Jia people from village is diagnosed as moderate atrophic gastritis intestinal moderate through Gansu Province's San Jia large hospital, and be invalid orchid doctor Second Academy hospitalization three months, after fail to respond to any medical treatment to the Zong Yuan of northwest ground force again and leave hospital, come here to take oral liquid of the present invention after multi-treatment is invalid, recovery from illness in three months is followed up a case by regular visits to and is not had recurrence.
Case 5: Zhu * *, the man, 70 years old, Jinchang two ore deposit workers, atrophic gastritis is suffered from retirement, and in the treatment of ground such as Jinchang, Lanzhou, multiple medicine is invalid, comes the here treatment on April 7th, 2006, takes medicinal granule of the present invention, recovery from illness in two months.
Following embodiment all can realize the effect of above-mentioned experimental example.
The specific embodiment
Embodiment 1: the preparation of pill
Radix Astragali 115kg Radix Rehmanniae Preparata 10kg Radix Codonopsis 60kg
Rhizoma Dioscoreae 40kg Radix Paeoniae Alba 10kg Cortex Moutan 10kg
Ramulus Cinnamomi 6kg Poria 15kg Fructus Jujubae 6kg
Cortex Cinnamomi 15kg Radix Aconiti Lateralis Preparata 15kg Fructus Lycii 30kg
Rhizoma Alismatis 6kg Radix Glycyrrhizae 10kg Rhizoma Atractylodis Macrocephalae 15kg
Rhizoma Zingiberis 10kg Fructus Corni 30kg
Said medicine technology routinely adds conventional adjuvant and makes pill, every 9g, and service once every day sooner or later ante cibum, each 1 of light disease, each 3 of serious symptom.
Embodiment 2: the preparation of decoction
Radix Astragali 170kg Radix Rehmanniae Preparata 6kg Radix Codonopsis 90kg
Rhizoma Dioscoreae 25kg Radix Paeoniae Alba 14kg Cortex Moutan 6kg
Ramulus Cinnamomi 8kg Poria 8kg Fructus Jujubae 8kg
Cortex Cinnamomi 8kg Radix Aconiti Lateralis Preparata 20kg Fructus Lycii 20kg
Rhizoma Alismatis 8kg Radix Glycyrrhizae 6kg Rhizoma Atractylodis Macrocephalae 20kg
Rhizoma Zingiberis 6kg Fructus Corni 40kg
Said medicine technology routinely adds conventional adjuvant and makes decoction.
Embodiment 3: the preparation of powder
Radix Astragali 70kg Radix Rehmanniae Preparata 14kg Radix Codonopsis 40kg
Rhizoma Dioscoreae 50kg Radix Paeoniae Alba 6kg Cortex Moutan 14kg
Ramulus Cinnamomi 4kg Poria 20kg Fructus Jujubae 5kg
Cortex Cinnamomi 20kg Radix Aconiti Lateralis Preparata 8kg Fructus Lycii 40kg
Rhizoma Alismatis 4kg Radix Glycyrrhizae 14kg Rhizoma Atractylodis Macrocephalae 8kg
Rhizoma Zingiberis 14kg Fructus Corni 20kg
Said medicine technology routinely adds conventional adjuvant and makes powder.
Embodiment 4: the preparation of tablet
Radix Astragali Preparata 115kg Radix Rehmanniae Preparata 10kg Radix Codonopsis 60kg
Rhizoma Dioscoreae 40kg Radix Paeoniae Alba (parched) 10kg Cortex Moutan 10kg
Ramulus Cinnamomi 6kg Poria 15kg Fructus Jujubae 6kg
Cortex Cinnamomi 15kg Radix Aconiti Lateralis Preparata 15kg Fructus Lycii 30kg
Rhizoma Alismatis 6kg Radix Glycyrrhizae 10kg Rhizoma Atractylodis Macrocephalae 15kg
Rhizoma Zingiberis 10kg Fructus Corni 30kg
Said medicine technology routinely adds conventional adjuvant and makes tablet.
Embodiment 5: the preparation of oral liquid
Radix Astragali Preparata 170kg Radix Rehmanniae Preparata 6kg Radix Codonopsis 90kg
Rhizoma Dioscoreae 25kg Radix Paeoniae Alba (parched) 14kg Cortex Moutan 6kg
Ramulus Cinnamomi 8kg Poria 8kg Fructus Jujubae 8kg
Cortex Cinnamomi 8kg Radix Aconiti Lateralis Preparata 20kg Fructus Lycii 20kg
Rhizoma Alismatis 8kg Radix Glycyrrhizae 6kg Rhizoma Atractylodis Macrocephalae 20kg
Rhizoma Zingiberis 6kg Fructus Corni 40kg
Said medicine technology routinely adds conventional adjuvant and makes oral liquid.
Embodiment 6: the preparation of capsule
Radix Astragali 70kg Radix Rehmanniae Preparata 14kg Radix Codonopsis 40kg
Rhizoma Dioscoreae 50kg Radix Paeoniae Alba 6kg Cortex Moutan 14kg
Ramulus Cinnamomi 4kg Poria 20kg Fructus Jujubae 5kg
Cortex Cinnamomi 20kg Radix Aconiti Lateralis Preparata 8kg Fructus Lycii 40kg
Rhizoma Alismatis 4kg Radix Glycyrrhizae 14kg Rhizoma Atractylodis Macrocephalae 8kg
Rhizoma Zingiberis 14kg Fructus Corni 20kg
Said medicine technology routinely adds conventional adjuvant and makes capsule.
Embodiment 7: the preparation of granule
Radix Astragali 115kg Radix Rehmanniae Preparata 10kg Radix Codonopsis 60kg
Rhizoma Dioscoreae 40kg Radix Paeoniae Alba 10kg Cortex Moutan 10kg
Ramulus Cinnamomi 6kg Poria 15kg Fructus Jujubae 6kg
Cortex Cinnamomi 15kg Radix Aconiti Lateralis Preparata 15kg Fructus Lycii 30kg
Rhizoma Alismatis 6kg Radix Glycyrrhizae 10kg Rhizoma Atractylodis Macrocephalae 15kg
Rhizoma Zingiberis 10kg Fructus Corni 30kg
Said medicine technology routinely adds conventional adjuvant and makes granule.

Claims (9)

1. pharmaceutical composition for the treatment of atrophic gastritis or superficial gastritis is characterized in that the crude drug of said composition consists of:
Radix Astragali 50-180 weight portion Radix Rehmanniae Preparata 5-15 weight portion Radix Codonopsis 30-100 weight portion
Rhizoma Dioscoreae 20-60 weight portion Radix Paeoniae Alba 5-15 weight portion Cortex Moutan 5-15 weight portion
Ramulus Cinnamomi 3-9 weight portion Poria 7-23 weight portion Fructus Jujubae 3-9 weight portion
Cortex Cinnamomi 7-23 weight portion Radix Aconiti Lateralis Preparata 7-23 weight portion Fructus Lycii 15-45 weight portion
Rhizoma Alismatis 3-9 weight portion Radix Glycyrrhizae 5-15 weight portion Rhizoma Atractylodis Macrocephalae 7-23 weight portion
Rhizoma Zingiberis 5-15 weight portion Fructus Corni 15-45 weight portion.
2. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of said composition consists of:
The Radix Astragali 115 weight portion Radix Rehmanniaes Preparata 10 weight portion Radix Codonopsis 60 weight portions
The Rhizoma Dioscoreae 40 weight portion Radix Paeoniae Albas 10 weight portion Cortex Moutans 10 weight portions
Ramulus Cinnamomi 6 weight portion Poria 15 weight portion Fructus Jujubaes 6 weight portions
Cortex Cinnamomi 15 weight portion Radix Aconiti Lateralis Preparatas 15 weight portion Fructus Lyciis 30 weight portions
The Rhizoma Alismatis 6 weight portion Radix Glycyrrhizaes 10 weight portion Rhizoma Atractylodis Macrocephalaes 15 weight portions
Rhizoma Zingiberis 10 weight portion Fructus Corni 30 weight portions.
3. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of said composition consists of:
The Radix Astragali 170 weight portion Radix Rehmanniaes Preparata 6 weight portion Radix Codonopsis 90 weight portions
The Rhizoma Dioscoreae 25 weight portion Radix Paeoniae Albas 14 weight portion Cortex Moutans 6 weight portions
Ramulus Cinnamomi 8 weight portion Poria 8 weight portion Fructus Jujubaes 8 weight portions
Cortex Cinnamomi 8 weight portion Radix Aconiti Lateralis Preparatas 20 weight portion Fructus Lyciis 20 weight portions
The Rhizoma Alismatis 8 weight portion Radix Glycyrrhizaes 6 weight portion Rhizoma Atractylodis Macrocephalaes 20 weight portions
Rhizoma Zingiberis 6 weight portion Fructus Corni 40 weight portions.
4. pharmaceutical composition as claimed in claim 1 is characterized in that the crude drug of said composition consists of:
The Radix Astragali 70 weight portion Radix Rehmanniaes Preparata 14 weight portion Radix Codonopsis 40 weight portions
The Rhizoma Dioscoreae 50 weight portion Radix Paeoniae Albas 6 weight portion Cortex Moutans 14 weight portions
Ramulus Cinnamomi 4 weight portion Poria 20 weight portion Fructus Jujubaes 5 weight portions
Cortex Cinnamomi 20 weight portion Radix Aconiti Lateralis Preparatas 8 weight portion Fructus Lyciis 40 weight portions
The Rhizoma Alismatis 4 weight portion Radix Glycyrrhizaes 14 weight portion Rhizoma Atractylodis Macrocephalaes 8 weight portions
Rhizoma Zingiberis 14 weight portion Fructus Corni 20 weight portions.
5. according to the arbitrary described pharmaceutical composition of claim 1-4, it is characterized in that the described Radix Astragali is a Radix Astragali Preparata, the Rhizoma Atractylodis Macrocephalae is a Rhizoma Atractylodis Macrocephalae (parched).
6. according to the arbitrary described pharmaceutical composition of claim 1-4, it is characterized in that said composition adds conventional adjuvant by practice of pharmacy and makes the decoction of clinical acceptance, pill, powder, tablet, oral liquid, capsule or granule.
7. pharmaceutical composition according to claim 5 is characterized in that said composition adds conventional adjuvant by practice of pharmacy and makes the decoction of clinical acceptance, pill, powder, tablet, oral liquid, capsule or granule.
8. according to the application of the arbitrary described pharmaceutical composition of claim 1-4 in the medicine of preparation treatment atrophic gastritis or superficial gastritis.
9. the application of pharmaceutical composition according to claim 5 in the medicine of preparation treatment atrophic gastritis or superficial gastritis.
CN2007101755390A 2007-09-30 2007-09-30 Medicine composition for treating chronic gastritis Expired - Fee Related CN101396548B (en)

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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103182059B (en) * 2013-03-18 2014-10-08 上海中医药大学附属岳阳中西医结合医院 Traditional Chinese medicine composition for treating chronic gastritis, and application thereof
CN103341140B (en) * 2013-07-05 2015-10-28 张海英 A kind of Chinese patent medicine promoting gastrointestinal function and preparation method thereof
CN103386110B (en) * 2013-08-01 2015-06-03 中国药材公司 Chinese medicine composition, and preparation method and applications thereof
CN103977379A (en) * 2014-05-29 2014-08-13 蚌埠明日欣医药有限公司 Traditional Chinese medicine preparation for treating bile reflux gastritis
CN106490558A (en) * 2016-09-19 2017-03-15 陈亚杰 A kind of health-care honey and preparation method thereof
CN110898202A (en) * 2019-12-04 2020-03-24 淮安市淮安医院 Biological medicine and medical food for digestive tract diseases and preparation method thereof
CN112220910A (en) * 2020-11-26 2021-01-15 璧电户 Traditional Chinese medicine composition containing monkshood and preparation method thereof
CN113117043A (en) * 2021-05-26 2021-07-16 张家港市中医医院 Traditional Chinese medicine composition for treating metastatic gastric cancer

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094959A (en) * 1993-05-13 1994-11-16 山东省医学科学院基础医学研究所 A kind of Chinese medicine for the treatment of gastropathy
CN1146908A (en) * 1995-11-24 1997-04-09 何亚长 Chinese medicine preparation for treatment of gastric ulcer, duodenal ulcer and gastritis
CN1864727A (en) * 2006-02-07 2006-11-22 彭安泽 A medicine for treating chronic gastritis
CN101041047A (en) * 2007-04-19 2007-09-26 于振鹏 Chinese traditional medicine compound took orally for treating chronic superficial gastritis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1094959A (en) * 1993-05-13 1994-11-16 山东省医学科学院基础医学研究所 A kind of Chinese medicine for the treatment of gastropathy
CN1146908A (en) * 1995-11-24 1997-04-09 何亚长 Chinese medicine preparation for treatment of gastric ulcer, duodenal ulcer and gastritis
CN1864727A (en) * 2006-02-07 2006-11-22 彭安泽 A medicine for treating chronic gastritis
CN101041047A (en) * 2007-04-19 2007-09-26 于振鹏 Chinese traditional medicine compound took orally for treating chronic superficial gastritis

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