CN101112513A - Chinese traditional medicine preparations for treating threatened abortion - Google Patents

Chinese traditional medicine preparations for treating threatened abortion Download PDF

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Publication number
CN101112513A
CN101112513A CNA2007101209118A CN200710120911A CN101112513A CN 101112513 A CN101112513 A CN 101112513A CN A2007101209118 A CNA2007101209118 A CN A2007101209118A CN 200710120911 A CN200710120911 A CN 200710120911A CN 101112513 A CN101112513 A CN 101112513A
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China
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radix
parts
chinese medicine
threatened abortion
traditional chinese
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CNA2007101209118A
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Chinese (zh)
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王信锁
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Beijing Yixintang Medicine Institute
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Beijing Yixintang Medicine Institute
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Priority to CNA2007101209118A priority Critical patent/CN101112513A/en
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Abstract

The present invention relates to a traditional Chinese medicine preparation for treating threatened abortion, which takes more than 10 Chinese herbal medicines of baical skullcap root, golden thread, carbonized lotus rhizome node, yerbadetajo herb etc. as the raw materials. The present invention has the effects of clearing heat, cooling blood and stopping bleeding for preventing miscarriage. Based on the differential treatment of the traditional Chinese medicine, the invention is developed by combining the latest scientific research results with the traditional Chinese medicine. The present invention aims at providing the traditional Chinese medicine preparation for treating threatened abortion. The present invention is characterized by accurate efficacy, safety, convenience, no toxicity or side effects and low price.

Description

A kind of Chinese medicine preparation of treatment threatened abortion
Technical field
The present invention relates to treat a kind of Chinese medicine preparation of threatened abortion, is that a kind of threatened abortion for the treatment of is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
Miscarriage is meant that the clinical manifestation of miscarriage is vaginal hemorrhage and the different stomachache of degree after the menolipsis gestation before 28 weeks, the not enough 1000g of fetal weight and termination person.Miscarriage is human reproduction's natural selection, account for 75% of germ cell, wherein only about 15% because of have the miscarriage symptom by clinical understanding, remaining then often shows as dysfunctional uterine bleeding, delayed period etc., germ cell in early days promptly by natural selection and not known, this is a kind of phenomenon of screening naturally that produces offspring, and miscarriage has play a part certain to option of species really.The cardinal symptom and the residing different phase thereof that are showed in the process according to miscarriage are divided into threatened abortion, habitual abortion, inevitable abortion, incomplete abortion, artificial abortion and missed abortion.The category such as " vaginal bleeding during pregnancy ", " frequent fetal movement ", " abdominal pain during pregnancy ", " habitual abortion ", " induced abortion ", " abortion ", " abortion within the first month of pregnancy ", " inevitable abortion ", " retention of dead fetus " that belongs to Chinese medicine respectively.Before threatened abortion is meant pregnant 28 weeks, occur a small amount of colporrhagia or (with) lower abdominal pain, palace strength mouth is not opened, fetal membrane is broken, pregnant thing is discharged as yet, gestation still is hopeful the continuator.The treatment threatened abortion main principle be antiabortive, prevent miscarriage.Antiabortive method should be based on the kidney invigorating, benefiting QI and nourishing blood.Kidney qi is contained, and tire has direct bearing; The prosperous then tire of gas has contained; Blood fills that then tire is foster to some extent, and its tire is from peace.Simultaneously, facing card should be in line with the principle of " treatment must aim at the pathogenesis of disease ", divides the cold and heat and asthenia and sthenia of differential diagnosis of diseases, according to the different causes of disease adopt the kidney invigorating, spleen invigorating, QI invigorating, the heat clearing away of nourishing blood respectively, the method such as antiabortive of regulating the flow of vital energy, invigorate blood circulation, detoxify, to reach antiabortive purpose.The side's of sending medication should notice that temperature compensation should not be too hot, and regulating QI should not be too hot dry, and too bitter cold is not wanted in heat clearing away, must not regulate the flow of vital energy and too dissipates.And the product of blood stasis dispelling, tonneau should be scrupulous, if really due to illness feelings need, should the ancestor principle of " decline its more than half and end ", middle disease is promptly ended.The traditional Chinese medical science divide clinically suffer from a deficiency of the kidney, disease type Coryza Treated by Syndrome Differentiation such as deficient qi and blood, heat in blood, stagnation of liver-QI, blood stasis, wound, obtain very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of threatened abortion.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by following raw materials by weight proportions:
1.0~4 parts of 1.0~4 portions of Rhizoma Dioscoreaes of 1.5~6 parts of Herba Taxillis of Radix Rehmanniae
0.1~2 part of 1.0~4 parts of Radix Dipsaci of 1.0~4 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
0.1~2 part of 0.1~2 part of Radix Scutellariae of 1.0~4 portions of Herba Ecliptaes of Radix Ophiopogonis
0.1~1 part of 0.1~2 portion of Rhizoma Coptidis of 1.0~4 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
The weight proportion of each crude drug of optimization formula of the present invention is:
1.5~2.5 parts of 1.5~2.5 portions of Rhizoma Dioscoreaes of 2.5~3.5 parts of Herba Taxillis of Radix Rehmanniae
0.5~1.5 part of 1.5~2.5 parts of Radix Dipsaci of 1.5~2.5 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
0.5~1.5 part of 0.5~1.5 part of Radix Scutellariae of 1.5~2.5 portions of Herba Ecliptaes of Radix Ophiopogonis
0.3~0.7 part of 0.5~1.5 portion of Rhizoma Coptidis of 1.5~2.5 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
The weight proportion of each crude drug of optimum formula of the present invention is:
2 parts of 2 portions of Rhizoma Dioscoreaes of 3 parts of Herba Taxillis of Radix Rehmanniae
1 part of 2 parts of Radix Dipsaci of 2 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
1 part of 1 part of Radix Scutellariae of 2 portions of Herba Ecliptaes of Radix Ophiopogonis
0.5 part of 1 portion of Rhizoma Coptidis of 2 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
Drug action mechanism among the present invention is as follows:
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Ophiopogonis property of medicine is slightly cold.Return lung, stomach, heart channel.Has nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, the effect of the relieving restlessness that clears away heart-fire.Can treat dryness of the lung dry cough, lung abscess, deficiency of YIN chronic cough, Tianjin wound is thirsty, quenches one's thirst, and vexed insomnia is had sore throat, the dryness of the intestine constipation, heat in blood is told nosebleed etc.(the 1430th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Paeoniae Alba (parched) property of medicine hardship, acid are slightly cold.Return liver, spleen channel.Have and nourish blood and seek relieving spasm to stop pain, the effect of yin fluid astringing suppressing the hyperactive liver.Can treat the blood deficiency cold and heat, epigastric pain, hypochondriac pain, limb spasm pain, dysmenorrhea, menoxenia, metrorrhagia, spontaneous perspiration, night sweat, dysentery is had loose bowels, and it is dizzy to have a headache etc.(the 948th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Herba Taxilli property of medicine hardship, sweet, flat.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, antiabortive effect.Can treat soreness of waist and knee joint, a little less than the muscles and bones flaccidity, limbs are hemiplegia, rheumatic arthralgia, and Light-headedness is had blood in stool, frequent fetal movement, metrostaxis, lack of lactation after delivery etc.(the 2789th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The charred Nodus Nelumbinis Rhizomatis property of medicine is sweet, puckery, and is flat.Return liver, lung, stomach warp.Has dissipating blood stasis hemostatic effect.Can treat haematemesis, spitting of blood, hematuria is had blood in stool, dysentery, metrorrhagia etc.(the 3799th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Herba Ecliptae property of medicine is sweet, sour, cold.Return liver, kidney channel.Has liver and kidney tonifying, cooling blood for hemostasis.Can treat deficiency of the liver and kindey, have a dizzy spell, early whitening of beard and hair is spitted blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage etc.(the 3690th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Boehmeriae property of medicine is sweet, and is cold.Return liver, the heart, urinary bladder channel.Has cooling blood for hemostasis, clearing heat and preventing abortion, diuresis, antidotal effect.Can treat spitting of blood, haematemesis, epistaxis, stranguria with blood due to the bleeding due to blood-heat, have blood in stool, metrorrhagia, purpura, frequent fetal movement, vaginal bleeding during pregnancy hematochezia, dribbling urination, carbuncle pyogenic infections from tumour or sore, worm venom etc.(the 1495th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Dipsaci property of medicine hardship, suffering, tepor.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, the effect of ending metrorrhagia.Can treat aching pain in waist and back, the podomere flaccidity syndrome and arthralgia syndrome falls and pounces on wound, decreases muscle folding bone, and fetal movement is leaked red, metrorrhagia, and seminal emission, leukorrhagia, the carbuncle skin ulcer is swollen etc.(the 3172nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Scutellariae property of medicine hardship, cold.Return lung, the heart, liver, gallbladder, large intestine channel.Has clearing away heat-fire, dampness detoxifcation, hemostasis, antiabortive effect.Can treat the cough due to lung-heat, the calentura unconsciousness due to high fever, the liver-fire headache, conjunctival congestion and swelling pain, jaundice due to damp-heat, dysentery, pyretic stranguria is told nosebleed, metrorrhagia, excessive fetal movement due to heat in pregnancy, carbuncle furuncle etc.(the 2808th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Rhizoma Coptidis nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine channel.Has clearing away heat-fire, dampness, antidotal effect.Can treat the calentura heresy and go into the hyperpyrexia of heart channel, agitation, delirium or the absurd row of intenseness of heat forcing blood tell nosebleed, the damp and hot feeling of stuffiness in chest is had loose bowels, dysentery, the vexed insomnia of hyperactivity of heart-fire, gastropyretic vomiting, rapid digestion of food and polyorexia, liver-fire conjunctival congestion and swelling pain, and pathopyretic ulcer, the furunculosis septicemia, gingival swelling and pain, aphtha of the mouth and tongue, hemorrhoidal bleeding, eczema is scalded etc.(the 2818th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Radix Rehmanniae, Radix Scutellariae and Rhizoma Coptidis; With Rhizoma Dioscoreae, Semen Cuscutae, Radix Ophiopogonis, Radix Paeoniae Alba (parched), Herba Taxilli and charred Nodus Nelumbinis Rhizomatis is ministerial drug; With Radix Dipsaci, Herba Ecliptae and Radix Boehmeriae is adjuvant.All medicines are harmonious, and are total to the tool clearing away heat and cooling blood, the effect of arresting bleeding and miscarriage prevention.The treatment threatened abortion has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of The Drug Administration Law of People's Republic of China, utilizes the comprehensive function treatment threatened abortion of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention not only can effectively treat threatened abortion, and the prevention of threatened abortion is also had good effect, and the treatment threatened abortion has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results: treatment threatened abortion patient 18 examples to the treatment threatened abortion.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.One month is a course of treatment, take continuously three the course of treatment observe the curative effect.8 examples of fully recovering account for 44.44%, and 8 examples that take a turn for the better account for 44.44%, and invalid 2 examples account for 11.11%, and total effective rate reaches 88.88%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction is pressed following weight weighting raw materials:
2 parts of 2 portions of Rhizoma Dioscoreaes of 3 parts of Herba Taxillis of Radix Rehmanniae
1 part of 2 parts of Radix Dipsaci of 2 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
1 part of 1 part of Radix Scutellariae of 2 portions of Herba Ecliptaes of Radix Ophiopogonis
0.5 part of 1 portion of Rhizoma Coptidis of 2 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
Preparation method is to get the above-mentioned raw materials medicine to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5~2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1~1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the treatment threatened abortion that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.One month is a course of treatment.

Claims (3)

1. a kind of Chinese medicine preparation of treatment threatened abortion is characterized in that it is made by following raw materials by weight proportions:
1.0~4 parts of 1.0~4 portions of Rhizoma Dioscoreaes of 1.5~6 parts of Herba Taxillis of Radix Rehmanniae
0.1~2 part of 1.0~4 parts of Radix Dipsaci of 1.0~4 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
0.1~2 part of 0.1~2 part of Radix Scutellariae of 1.0~4 portions of Herba Ecliptaes of Radix Ophiopogonis
0.1~1 part of 0.1~2 portion of Rhizoma Coptidis of 1.0~4 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
2. a kind of Chinese medicine preparation of treatment threatened abortion according to claim 1, wherein the weight proportion of each crude drug is:
1.5~2.5 parts of 1.5~2.5 portions of Rhizoma Dioscoreaes of 2.5~3.5 parts of Herba Taxillis of Radix Rehmanniae
0.5~1.5 part of 1.5~2.5 parts of Radix Dipsaci of 1.5~2.5 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
0.5~1.5 part of 0.5~1.5 part of Radix Scutellariae of 1.5~2.5 portions of Herba Ecliptaes of Radix Ophiopogonis
0.3~0.7 part of 0.5~1.5 portion of Rhizoma Coptidis of 1.5~2.5 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
3. a kind of Chinese medicine preparation of treatment threatened abortion according to claim 1, wherein the weight proportion of each crude drug is:
2 parts of 2 portions of Rhizoma Dioscoreaes of 3 parts of Herba Taxillis of Radix Rehmanniae
1 part of 2 parts of Radix Dipsaci of 2 parts of charred Nodus Nelumbinis Rhizomatis of Semen Cuscutae
1 part of 1 part of Radix Scutellariae of 2 portions of Herba Ecliptaes of Radix Ophiopogonis
0.5 part of 1 portion of Rhizoma Coptidis of 2 parts of Radix Boehmeriaes of Radix Paeoniae Alba (parched).
CNA2007101209118A 2007-08-29 2007-08-29 Chinese traditional medicine preparations for treating threatened abortion Pending CN101112513A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103285232A (en) * 2013-05-17 2013-09-11 周波 Traditional Chinese medicine for preventing habitual abortion
CN103536838A (en) * 2013-10-18 2014-01-29 李佃场 Traditional Chinese medicine preparation for treating threatened abortion and preparation method thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103285232A (en) * 2013-05-17 2013-09-11 周波 Traditional Chinese medicine for preventing habitual abortion
CN103536838A (en) * 2013-10-18 2014-01-29 李佃场 Traditional Chinese medicine preparation for treating threatened abortion and preparation method thereof
CN103536838B (en) * 2013-10-18 2016-03-09 霍军伟 A kind of Chinese medicine preparation for the treatment of threatened abortion and preparation method thereof

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Open date: 20080130