CN101095794A - Chinese traditional medicine preparations for treating drug-induced nephritis - Google Patents
Chinese traditional medicine preparations for treating drug-induced nephritis Download PDFInfo
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- CN101095794A CN101095794A CNA2007101183175A CN200710118317A CN101095794A CN 101095794 A CN101095794 A CN 101095794A CN A2007101183175 A CNA2007101183175 A CN A2007101183175A CN 200710118317 A CN200710118317 A CN 200710118317A CN 101095794 A CN101095794 A CN 101095794A
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Abstract
The invention relates to a Chinese medicinal combination for treating nephritis which is prepared from more than ten kinds of Chinese medicinal herbs including dodder seed, motherwort, codonopsis pilosula and glutinous rehmannia. The medicament has the advantages of assured curative effect, safe and convenient application, no toxic and side effects, and low price.
Description
Technical field
The present invention relates to the Chinese medicine preparation of medicine nephritis, is that a kind of medicine nephritis is the Chinese medicine preparation of raw material with the Chinese herbal medicine.Belong to the field of Chinese medicines.
Background technology
The kidney damage that is caused by all kinds of Chinese and western drugses is called the medicine renal damage.Kidney is the main Excretory organ of body, and except the drainage of bearing body substance metabolism end-product, the various drug mains that human body is taken will also be to excrete with original shape or its metabolite by kidney.The discharge process of medicine comprises that glomerular filtration, tubular secretion and renal tubules heavily absorb three links, so the whether normal of renal function will directly influence the curative effect of medicine.Simultaneously, medicine contacts with renal tissue in discharge process, also can cause the toxicity damage to nephridial tissue.Drug-induced renal damage increases at present day by day, mainly shows as nephrotoxicity reaction and anaphylaxis.Along with growth in the living standard, the randomness of taking medicine increases, and the generation of medicine renal damage also has the tendency that more and more increases.Not only Western medicine antibiotic, immunosuppressant, contrast agent, analgesics etc. can cause renal damage, and the renal damage due to the Chinese medicine improper use also constantly is found.Still do not have corresponding name of disease in the Chinese medicine, generally can be familiar with reference to " blood disorder ", " stranguria ", " lumbago ", " difficulty in urination ", " obstruction and rejection ".
The traditional Chinese medical science divides poison of drug to hinder the resistance of network, kidney network numbness, feeble and exhausted, the obstruction of QI of kidney yang clinically, disease type Coryza Treated by Syndrome Differentiation such as closes in the turbid damp, obtains very good effect.Invent a kind of not only safety but also effective Chinese medicine preparation, be significant.
Summary of the invention
The present invention develops in conjunction with the latest modern technological scientific achievement on the basis of traditional tcm syndrome differentiation and treatment.The Chinese medicine preparation that the purpose of this invention is to provide the medicine nephritis.Have determined curative effect, safe ready, have no side effect, cheap characteristics.
The present invention is made by the following weight proportion raw material:
0.1～2 part of 1.0～4 portions of Cortex Cinnamomi of 1.5～6 parts of Poria of Herba Leonuri
0.1～2 part of 1.0～4 parts of Fructus Corni of 1.5～6 portions of Rhizoma Alismatis of Semen Cuscutae
0.1～2 part of 1.0～4 portions of Radix Cyathulae of 1.0～4 parts of Radix Codonopsis of Radix Rehmanniae
0.1～1 part of 1.0～4 parts of Radix Aconiti Lateralis Preparata of 1.0～4 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
The weight proportion of each raw material of optimization formula of the present invention is:
0.5～1.5 part of 1.5～2.5 portions of Cortex Cinnamomi of 2.5～3.5 parts of Poria of Herba Leonuri
0.5～1.5 part of 1.5～2.5 parts of Fructus Corni of 2.5～3.5 portions of Rhizoma Alismatis of Semen Cuscutae
0.5～1.5 part of 1.5～2.5 portions of Radix Cyathulae of 1.5～2.5 parts of Radix Codonopsis of Radix Rehmanniae
0.3～0.7 part of 1.5～2.5 parts of Radix Aconiti Lateralis Preparata of 1.5～2.5 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
The weight proportion of each raw material of optimum formula of the present invention is:
1 part of 2 portions of Cortex Cinnamomi of 3 parts of Poria of Herba Leonuri
1 part of 2 parts of Fructus Corni of 3 portions of Rhizoma Alismatis of Semen Cuscutae
1 part of 2 portions of Radix Cyathulae of 2 parts of Radix Codonopsis of Radix Rehmanniae
0.5 part of 2 parts of Radix Aconiti Lateralis Preparata of 2 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
Drug action mechanism among the present invention is as follows:
Herba Leonuri property of medicine suffering, hardship are slightly cold.Return liver, kidney, pericardium channel.Has promoting blood flow to regulate menstruation, inducing diuresis to remove edema, the effect of heat-clearing and toxic substances removing.Can treat menoxenia, amenorrhea, vaginal bleeding during pregnancy difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, traumatic injury, dysuria, edema, carbuncle skin infection etc.(the 2697th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Semen Cuscutae property of medicine suffering, sweet, flat.Return the liver,kidney,spleen warp.Have the kidney invigorating and essence nourishing, Gu nourishing the liver to improve visual acuity is the effect of tire stopping leak.Can treat soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, miscarriage is had loose bowels etc.(the 2896th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Rehmanniae nature and flavor are sweet, cold.GUIXIN, liver, kidney channel.Has clearing away heat and cooling blood, yin nourishing, the effect of promoting the production of body fluid.Can treat that calentura crimson tongue excessive thirst, interior-heat caused by deficiency of YIN, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, haematemesis, epistaxis, send out speckle dermexanthesis etc.(Ji Yubin chief editor " Chinese medicine medicine for preventing pharmacology and application " Heilungkiang science tech publishing house 1999 version the 514th page).
The Rhizoma Dioscoreae property of medicine is sweet, flat.Return spleen, lung, kidney channel.Have spleen reinforcing, support lung, reinforce the kidney, the effect that benefit is smart.Can treat diarrhea due to hypofunction of the spleen, the lack of appetite edema, cough and asthma due to lung deficiency is quenched one's thirst, seminal emission, leukorrhagia, the frequent micturition of suffering from a deficiency of the kidney.Carbuncle is controlled in external, scrofula etc.(the 218th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Poria property of medicine is sweet, light, and is flat.GUIXIN, spleen, lung, kidney channel.Has promoting diuresis to eliminate damp pathogen, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Can treat dysuria, the edema distension, is had loose bowels at phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, palpitation and restlessness, insomnia forgetfulness, seminal emission nebulousurine etc.(the 2154th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Rhizoma Alismatis property of medicine is sweet, light, and is cold.Return kidney, urinary bladder channel.Have promoting diuresis to eliminate damp pathogen, treating stranguria effect expels the heat-evil.Can treat dysuria, the puckery pain of pyretic stranguria, the edema distension is had loose bowels, dizziness due to fluid-retention, seminal emission etc.(the 2067th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The Radix Codonopsis property of medicine is sweet, and is flat.Return spleen, lung meridian.Has strengthening the spleen and tonifying the lung, the effect of supplementing QI for promoting the production of body fluid.Can treat weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung is breathed with cough, the spontaneous perspiration of breathing hard, deficiency of both QI and blood etc.(the 2579th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little suffering of the Cortex Eucommiae property of medicine, temperature.Return liver, kidney channel.Has invigorating the liver and kidney, bone and muscle strengthening, antiabortive effect.Can treat soreness of waist and knee joint, sexual impotence, frequent micturition, dribbling urination, rheumatic arthralgia, frequent fetal movement, habitual abortion etc.(the 1514th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Cortex Cinnamomi property of medicine suffering, sweet, heat.Return kidney, spleen, the heart, Liver Channel.It is supporing yang to have the fire of benefit, dispersing cold for relieving pain, the effect of warming the meridian and promoting blood circulation.Can treat insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, the dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, the flushed complexion cold foot, dizziness and tinnitus, dispute is rotten broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain; Cold womb is infertile, the dysmenorrhea amenorrhea, and the stasis of blood stagnated and suffered from abdominal pain puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting etc.(the 1223rd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The acid of the Fructus Corni property of medicine, tepor.Return liver, kidney channel.Has liver and kidney tonifying, the effect that convergence is taken off admittedly.Can treat and have a dizzy spell, deafness and tinnitus, soreness of the waist and knees, emission and spermatorrhea, frequent micturition, incessant sweating due to debility, woman uterine bleeding etc.(the 248th page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Sweet, the little hardship of the Radix Cyathulae property of medicine, flat.Return liver, kidney channel.Has blood circulation promoting and blood stasis dispelling, the effect of expelling wind and removing dampness.Can treat the blood stasis amenorrhea, difficult labour, retention of placenta, postnatal blood stasis stomachache, pyretic stranguria, stranguria caused by urinary stone, dysmenorrhea, rheumatism lumbocrural pain, traumatic injury etc.(the 301st page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
Radix Aconiti Lateralis Preparata property of medicine suffering, sweet, heat, poisonous.GUIXIN, kidney, spleen channel.Has recuperating depleted YANG and rescuing the patient from collapse, the effect of dispelling cold and removing dampness.Can treat excessive YIN keeping YANG externally, loss of YANG due to profuse perspiration, vomiting and diarrhoea is fainted contrary, trusted subordinate's cold type of pain, cold-dysentery, beriberi edema, anemofrigid-damp arthralgia, the disease of the leakage of carbuncle of yin nature skin ulcer and all chronic diseaseses etc.(the 1672nd page of Shanghai science tech publishing house second edition write by " Chinese medicine voluminous dictionary " Nanjing University of Traditional Chinese Medicine).
The present invention follows the principles of formulating prescriptions of the traditional Chinese medical science " monarch ", is monarch drug with Cortex Cinnamomi, Radix Aconiti Lateralis Preparata, Radix Codonopsis and Semen Cuscutae; With Radix Rehmanniae, Rhizoma Dioscoreae, Fructus Corni, Poria and the Cortex Eucommiae is ministerial drug; With Rhizoma Alismatis, Radix Cyathulae and Herba Leonuri is adjuvant.All medicines are harmonious, and are total to the tool warming YANG and invigorating QI, the effect of invigorating kidney to promote diuresis.The medicine nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
Clinical drug of the present invention uses the result to show that following advantage is arranged:
1, the Chinese herbal medicine each component selected for use of the present invention meets the regulation of Pharmacopoeia of People's Republic of China, utilizes the comprehensive function medicine nephritis of the Chinese medicine of respectively distinguishing the flavor of, and is nontoxic to human body.Show that through the acute and chronic toxicity test of animal the animal of being tested does not see any toxic reaction, its main organs does not have tangible change yet, and safety of medicine is reliable.
2, rich in proteins in the medicine of the present invention, glucose, glucuronic acid, volatile oil, pectin, fructose, organic acid, lecithin, vitamin, aminoacid also contains various trace elements such as Saponin, plant sterol and calcium, is beneficial to absorption of human body, health invigorating.
3, the present invention's effective medicine nephritis not only also has good effect to the prevention of drug-induced nephritis, and the medicine nephritis has determined curative effect, has no side effect taking convenience, cheap characteristics.
For showing the therapeutic effect of medicine of the present invention, as follows through clinical test results to the medicine nephritis; Medicine nephritis patient 16 examples.Take the embodiment decoction, each 1 bag, two to three times on the one, take half an hour ante cibum.Three months is a course of treatment, take continuously three the course of treatment observe the curative effect.7 examples of fully recovering account for 43.75%, and 7 examples that take a turn for the better account for 43.75%, and invalid 2 examples account for 12.5%, and total effective rate reaches 87.5%.After three course of therapy, patient does not have any untoward reaction, and three big routine tests and hepatic and renal function detect no abnormal.
The specific embodiment
The embodiment decoction takes by weighing raw material by following weight:
1 part of 2 portions of Cortex Cinnamomi of 3 parts of Poria of Herba Leonuri
1 part of 2 parts of Fructus Corni of 3 portions of Rhizoma Alismatis of Semen Cuscutae
1 part of 2 portions of Radix Cyathulae of 2 parts of Radix Codonopsis of Radix Rehmanniae
0.5 part of 2 parts of Radix Aconiti Lateralis Preparata of 2 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
Preparation method is to get above-mentioned raw materials to clean roguing, dries, and is ground into granule, soaks 1 hour, puts and decocts with water secondary in the multi-function extractor, adds up the water of 10 times of amounts of medical material for the first time, decocts 1.5～2 hours, gets decocting liquid, filters.Add up for the second time the water of 7 times of amounts of medical material, decocted 1～1.2 hour, get decocting liquid twice, filter, in the heat-sealing bag, 105 ℃ of high temperature sterilizes, packing is promptly.The decoction of the medicine nephritis that the present invention makes is that plastic packaging is packed, and every bag of 210ml is oral, one time one bag, every day two to three times.Three months is a course of treatment.
Claims (3)
1, the Chinese medicine preparation of medicine nephritis is characterized in that it is made by the following weight proportion raw material:
0.1～2 part of 1.0～4 portions of Cortex Cinnamomi of 1.5～6 parts of Poria of Herba Leonuri
0.1～2 part of 1.0～4 parts of Fructus Corni of 1.5～6 portions of Rhizoma Alismatis of Semen Cuscutae
0.1～2 part of 1.0～4 portions of Radix Cyathulae of 1.0～4 parts of Radix Codonopsis of Radix Rehmanniae
0.1～1 part of 1.0～4 parts of Radix Aconiti Lateralis Preparata of 1.0～4 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
2, the Chinese medicine preparation of medicine nephritis according to claim 1, wherein the weight proportion of each raw material is:
0.5～1.5 part of 1.5～2.5 portions of Cortex Cinnamomi of 2.5～3.5 parts of Poria of Herba Leonuri
0.5～1.5 part of 1.5～2.5 parts of Fructus Corni of 2.5～3.5 portions of Rhizoma Alismatis of Semen Cuscutae
0.5～1.5 part of 1.5～2.5 portions of Radix Cyathulae of 1.5～2.5 parts of Radix Codonopsis of Radix Rehmanniae
0.3～0.7 part of 1.5～2.5 parts of Radix Aconiti Lateralis Preparata of 1.5～2.5 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
3, the Chinese medicine preparation of medicine nephritis according to claim 1, wherein the weight proportion of each raw material is:
1 part of 2 portions of Cortex Cinnamomi of 3 parts of Poria of Herba Leonuri
1 part of 2 parts of Fructus Corni of 3 portions of Rhizoma Alismatis of Semen Cuscutae
1 part of 2 portions of Radix Cyathulae of 2 parts of Radix Codonopsis of Radix Rehmanniae
0.5 part of 2 parts of Radix Aconiti Lateralis Preparata of 2 parts of Cortexs Eucommiae of Rhizoma Dioscoreae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2007101183175A CN101095794A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating drug-induced nephritis |
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| Application Number | Priority Date | Filing Date | Title |
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| CNA2007101183175A CN101095794A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating drug-induced nephritis |
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| Publication Number | Publication Date |
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| CN101095794A true CN101095794A (en) | 2008-01-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CNA2007101183175A Pending CN101095794A (en) | 2007-07-05 | 2007-07-05 | Chinese traditional medicine preparations for treating drug-induced nephritis |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103006979A (en) * | 2012-11-23 | 2013-04-03 | 王先忠 | Chinese medicinal composition for treating nephrotic edema |
| CN103623288A (en) * | 2013-12-06 | 2014-03-12 | 侯青兰 | Medication for treating chronic nephritis and preparation method of medication |
-
2007
- 2007-07-05 CN CNA2007101183175A patent/CN101095794A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103006979A (en) * | 2012-11-23 | 2013-04-03 | 王先忠 | Chinese medicinal composition for treating nephrotic edema |
| CN103006979B (en) * | 2012-11-23 | 2014-09-24 | 都丽平 | Chinese medicinal composition for treating nephrotic edema |
| CN103623288A (en) * | 2013-12-06 | 2014-03-12 | 侯青兰 | Medication for treating chronic nephritis and preparation method of medication |
| CN103623288B (en) * | 2013-12-06 | 2015-11-25 | 侯青兰 | A kind of medicine for the treatment of chronic nephritis and preparation method thereof |
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Open date: 20080102 |