CN100473278C - Bactericide composition with synergistic effect - Google Patents
Bactericide composition with synergistic effect Download PDFInfo
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- CN100473278C CN100473278C CNB2006100396447A CN200610039644A CN100473278C CN 100473278 C CN100473278 C CN 100473278C CN B2006100396447 A CNB2006100396447 A CN B2006100396447A CN 200610039644 A CN200610039644 A CN 200610039644A CN 100473278 C CN100473278 C CN 100473278C
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- thiophanate
- agent
- methyl
- tebuconazole
- weight ratio
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- 230000002195 synergetic effect Effects 0.000 title claims abstract description 25
- 239000000203 mixture Substances 0.000 title claims description 41
- 230000000844 anti-bacterial effect Effects 0.000 title abstract description 6
- 239000003899 bactericide agent Substances 0.000 title abstract description 5
- 239000005842 Thiophanate-methyl Substances 0.000 claims abstract description 54
- QGHREAKMXXNCOA-UHFFFAOYSA-N thiophanate-methyl Chemical compound COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC QGHREAKMXXNCOA-UHFFFAOYSA-N 0.000 claims abstract description 54
- PXMNMQRDXWABCY-UHFFFAOYSA-N 1-(4-chlorophenyl)-4,4-dimethyl-3-(1H-1,2,4-triazol-1-ylmethyl)pentan-3-ol Chemical compound C1=NC=NN1CC(O)(C(C)(C)C)CCC1=CC=C(Cl)C=C1 PXMNMQRDXWABCY-UHFFFAOYSA-N 0.000 claims abstract description 53
- 239000005839 Tebuconazole Substances 0.000 claims abstract description 53
- 239000000945 filler Substances 0.000 claims abstract description 22
- 241000209140 Triticum Species 0.000 claims abstract description 9
- 235000021307 Triticum Nutrition 0.000 claims abstract description 9
- 240000007594 Oryza sativa Species 0.000 claims abstract description 8
- 235000007164 Oryza sativa Nutrition 0.000 claims abstract description 8
- 240000006365 Vitis vinifera Species 0.000 claims abstract description 8
- 235000014787 Vitis vinifera Nutrition 0.000 claims abstract description 8
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract description 8
- 235000013399 edible fruits Nutrition 0.000 claims abstract description 8
- 235000009566 rice Nutrition 0.000 claims abstract description 8
- 235000012828 Citrullus lanatus var citroides Nutrition 0.000 claims abstract description 7
- 201000010099 disease Diseases 0.000 claims abstract description 7
- 235000013311 vegetables Nutrition 0.000 claims abstract description 6
- 244000241235 Citrullus lanatus Species 0.000 claims abstract 2
- 230000003641 microbiacidal effect Effects 0.000 claims description 22
- 229940124561 microbicide Drugs 0.000 claims description 22
- 239000002855 microbicide agent Substances 0.000 claims description 22
- 239000002994 raw material Substances 0.000 claims description 22
- 239000000843 powder Substances 0.000 claims description 20
- 238000009736 wetting Methods 0.000 claims description 17
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 15
- -1 polyoxyethylene triphenylethylene Polymers 0.000 claims description 11
- 230000000855 fungicidal effect Effects 0.000 claims description 10
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 9
- 230000002528 anti-freeze Effects 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 9
- 239000002270 dispersing agent Substances 0.000 claims description 9
- 239000006185 dispersion Substances 0.000 claims description 9
- 239000000375 suspending agent Substances 0.000 claims description 9
- 239000002562 thickening agent Substances 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 239000012752 auxiliary agent Substances 0.000 claims description 8
- 239000000417 fungicide Substances 0.000 claims description 8
- 239000000080 wetting agent Substances 0.000 claims description 8
- 235000009754 Vitis X bourquina Nutrition 0.000 claims description 7
- 235000012333 Vitis X labruscana Nutrition 0.000 claims description 7
- 239000002518 antifoaming agent Substances 0.000 claims description 7
- 229920001296 polysiloxane Polymers 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 claims description 6
- 229920001285 xanthan gum Polymers 0.000 claims description 5
- 239000005995 Aluminium silicate Substances 0.000 claims description 4
- 150000004996 alkyl benzenes Chemical class 0.000 claims description 4
- 235000012211 aluminium silicate Nutrition 0.000 claims description 4
- WMGSQTMJHBYJMQ-UHFFFAOYSA-N aluminum;magnesium;silicate Chemical compound [Mg+2].[Al+3].[O-][Si]([O-])([O-])[O-] WMGSQTMJHBYJMQ-UHFFFAOYSA-N 0.000 claims description 4
- 229940077388 benzenesulfonate Drugs 0.000 claims description 4
- 239000011575 calcium Substances 0.000 claims description 4
- 229910052791 calcium Inorganic materials 0.000 claims description 4
- 239000013530 defoamer Substances 0.000 claims description 4
- 235000011187 glycerol Nutrition 0.000 claims description 4
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 4
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 4
- 239000011734 sodium Substances 0.000 claims description 4
- 229910052708 sodium Inorganic materials 0.000 claims description 4
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 3
- 239000004927 clay Substances 0.000 claims description 3
- 229940088417 precipitated calcium carbonate Drugs 0.000 claims description 3
- 229920001732 Lignosulfonate Polymers 0.000 claims description 2
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 239000002253 acid Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000002131 composite material Substances 0.000 abstract description 2
- 241000607479 Yersinia pestis Species 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 description 25
- 239000003814 drug Substances 0.000 description 11
- 239000004546 suspension concentrate Substances 0.000 description 11
- 238000002360 preparation method Methods 0.000 description 10
- 238000005303 weighing Methods 0.000 description 10
- 244000141359 Malus pumila Species 0.000 description 9
- 235000011430 Malus pumila Nutrition 0.000 description 9
- 235000015103 Malus silvestris Nutrition 0.000 description 9
- 239000007788 liquid Substances 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 7
- 239000006229 carbon black Substances 0.000 description 6
- 239000004576 sand Substances 0.000 description 6
- 241000219109 Citrullus Species 0.000 description 5
- 206010039509 Scab Diseases 0.000 description 4
- RNMDNPCBIKJCQP-UHFFFAOYSA-N 5-nonyl-7-oxabicyclo[4.1.0]hepta-1,3,5-trien-2-ol Chemical compound C(CCCCCCCC)C1=C2C(=C(C=C1)O)O2 RNMDNPCBIKJCQP-UHFFFAOYSA-N 0.000 description 2
- 240000002791 Brassica napus Species 0.000 description 2
- 235000006008 Brassica napus var napus Nutrition 0.000 description 2
- TWFZGCMQGLPBSX-UHFFFAOYSA-N Carbendazim Natural products C1=CC=C2NC(NC(=O)OC)=NC2=C1 TWFZGCMQGLPBSX-UHFFFAOYSA-N 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000221785 Erysiphales Species 0.000 description 2
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 2
- 241000221662 Sclerotinia Species 0.000 description 2
- 240000003768 Solanum lycopersicum Species 0.000 description 2
- GAMFEMAXLMWCRG-UHFFFAOYSA-N bis(dimethylcarbamothioylsulfanyl)arsanyl n,n-dimethylcarbamodithioate Chemical compound CN(C)C(=S)S[As](SC(=S)N(C)C)SC(=S)N(C)C GAMFEMAXLMWCRG-UHFFFAOYSA-N 0.000 description 2
- 239000006013 carbendazim Substances 0.000 description 2
- JNPZQRQPIHJYNM-UHFFFAOYSA-N carbendazim Chemical compound C1=C[CH]C2=NC(NC(=O)OC)=NC2=C1 JNPZQRQPIHJYNM-UHFFFAOYSA-N 0.000 description 2
- 235000020971 citrus fruits Nutrition 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000005764 inhibitory process Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 241001465180 Botrytis Species 0.000 description 1
- 244000241257 Cucumis melo Species 0.000 description 1
- 235000015510 Cucumis melo subsp melo Nutrition 0.000 description 1
- 241000221787 Erysiphe Species 0.000 description 1
- 206010034133 Pathogen resistance Diseases 0.000 description 1
- 241000228150 Penicillium chrysogenum Species 0.000 description 1
- 241000233614 Phytophthora Species 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- 241001361634 Rhizoctonia Species 0.000 description 1
- 241001515786 Rhynchosporium Species 0.000 description 1
- 241001533598 Septoria Species 0.000 description 1
- 241001674251 Serpula lacrymans Species 0.000 description 1
- 241001674391 Sphaerulina musiva Species 0.000 description 1
- 229930182558 Sterol Natural products 0.000 description 1
- 241000082085 Verticillium <Phyllachorales> Species 0.000 description 1
- FJJCIZWZNKZHII-UHFFFAOYSA-N [4,6-bis(cyanoamino)-1,3,5-triazin-2-yl]cyanamide Chemical compound N#CNC1=NC(NC#N)=NC(NC#N)=N1 FJJCIZWZNKZHII-UHFFFAOYSA-N 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229920005551 calcium lignosulfonate Polymers 0.000 description 1
- 159000000007 calcium salts Chemical class 0.000 description 1
- RYAGRZNBULDMBW-UHFFFAOYSA-L calcium;3-(2-hydroxy-3-methoxyphenyl)-2-[2-methoxy-4-(3-sulfonatopropyl)phenoxy]propane-1-sulfonate Chemical compound [Ca+2].COC1=CC=CC(CC(CS([O-])(=O)=O)OC=2C(=CC(CCCS([O-])(=O)=O)=CC=2)OC)=C1O RYAGRZNBULDMBW-UHFFFAOYSA-L 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 230000017858 demethylation Effects 0.000 description 1
- 238000010520 demethylation reaction Methods 0.000 description 1
- 230000002554 disease preventive effect Effects 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000004992 fission Effects 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- JEIPFZHSYJVQDO-UHFFFAOYSA-N iron(III) oxide Inorganic materials O=[Fe]O[Fe]=O JEIPFZHSYJVQDO-UHFFFAOYSA-N 0.000 description 1
- 230000011278 mitosis Effects 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 150000003432 sterols Chemical class 0.000 description 1
- 235000003702 sterols Nutrition 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
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- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
A composite bactericide with synergistic action for preventing and eliminating the diseases and pests of fruit tree, grapevine, vegetables, watermelon, wheat and rice is prepared from tebuconazole (2-25 Wt%), thiophanate-methyl (10-75), assistant (3-25) and filler (10-70).
Description
Technical field
What the present invention relates to is a kind of microbicide compositions with synergistic effect; show extremely strong antibiotic and bactericidal activity; be applied to agricultural plant chemoproection field; be mainly used in control fruit tree, grape, vegetables, watermelon, wheat, the harm of paddy rice germ; crops are had protective effect and therapeutic action, and the said composition bactericide is different from existing other microbicide compositions.
Background technology
As everyone knows, thiophanate-methyl, Tebuconazole all are effective bactericide.Thiophanate-methyl interference cell fission process; crop had interior inhale protection and therapeutic action; very easily infiltration is converted into carbendazim in plant corpus; disturb the formation of spindle in the mitosis; influence cell division; to botrytis, sickle-like bacteria, wither spore bacterium, Penicillium notatum, septoria musiva bacterium, sclerotinite, black star bacterium, verticillium sp, rhizoctonia control efficiency is good for a short time, but phycomycetes, bacterium there is not preventive effect.Tebuconazole is a systemic fungicide, suppresses the sterol demethylation, the disease that control Rust that can be fabulous, Erysiphe, Rhynchosporium spp, nuclear cavity Pseudomonas and Septoria cause, but to phytophthora, dry rot fungus weak effect.
Summary of the invention
The objective of the invention is at above-mentioned weak point, a kind of microbicide compositions with synergistic effect is provided: thiophanate-methyl and Tebuconazole are composite, has obvious synergistic effect, enlarged fungicidal spectrum simultaneously, good to fruit, grape, vegetables, watermelon, wheat, rice disease control efficiency, surpass thiophanate-methyl, two medicament lists of Tebuconazole usefulness, and do not have cross resistance between the two.
Microbicide compositions with synergistic effect takes following scheme to realize: composition fungicide is made up of two kinds of active ingredient thiophanate-methyls and Tebuconazole, add auxiliary agent and filler and can be made into wetting powder or suspending agent, composition fungicide prepares each accounting example of raw materials by weight and is: Tebuconazole 2～25%, thiophanate-methyl 10～75%, auxiliary agent 3～25%, filler 10～70%.
The auxiliary agent of wetting powder is made up of dispersant 2～20% and wetting agent 1～5%, and per distribution ratio is for accounting for composition fungicide raw material weight per distribution ratio.Dispersant adopts lignosulfonates (calcium salt or sodium salt), NNO, draws back a kind of or mixture in the powder in the wetting powder; Wetting agent adopts sodium alkyl benzene sulfonate or alkyl benzene calcium sulfonate; Filler adopts a kind of or mixture in potter's clay, kaolin, diatomite, precipitated calcium carbonate, the white carbon black.
The auxiliary agent of suspending agent is made up of dispersion moisture agent 1～11%, antifreeze 1～3%, thickener 0.9～8%, defoamer 0.1～3%, and per distribution ratio is for accounting for composition fungicide raw material weight per distribution ratio.Dispersion moisture agent in the suspending agent adopts a kind of or mixture in polyoxyethylene triphenyl phosphorus hydrochlorate, alkylnaphthalene sulfonate, the alkylphenol polyoxyethylene; Antifreeze adopts a kind of in propane diols, glycerine, the ethylene glycol; Thickener adopts xanthans or aluminium-magnesium silicate; Defoamer adopts silicone defoaming agent; Filler adopts a kind of or mixture in water, the white carbon black.
Microbicide compositions with synergistic effect is used in control fruit tree, grape, vegetables, watermelon, wheat, all kinds of diseases of paddy rice.
Microbicide compositions preparation technology method with synergistic effect: composition is by said ratio weighing Tebuconazole and thiophanate-methyl, according to the product form of wanting to make is wetting powder or suspending agent, and auxiliary agent and filler that employing is filled a prescription separately, fully mix, after airslide disintegrating mill or sand mill grind, mix, promptly obtain finished product, finished product meets the every index request of country to wetting powder or suspending agent.
Microbicide compositions with synergistic effect is used in all kinds of diseases such as control fruit tree (apple, pears, citrus), grape, vegetables, melon, wheat, paddy rice, to crop safety, cost is low, preventive effect good.Prove that after tested microbicide compositions chemical property of the present invention is stable, synergy is remarkable, and controlling object is shown tangible synergy and complementation.
The advantage of combined bactericide: 1, these two kinds of combination of active principles are used, and have enlarged fungicidal spectrum.2, have synergistic effect, through test determination: thiophanate-methyl, Tebuconazole use the inhibition correlation coefficient (SR to the ring rot of apple bacterium separately
50) being respectively 0.99,0.97, Tebuconazole, thiophanate-methyl have synergistic effect to be used in combination in weight percent proportioning Tebuconazole 2～25%, thiophanate-methyl 10～75% scopes, are used in combination the inhibition correlation coefficient (SR to the ring rot of apple bacterium
50) be 1.50.Especially with Tebuconazole 10%, thiophanate-methyl 50%, synergy is the most remarkable.3, use cost reduces, and the Tebuconazole cost is higher at present, and it is not again fine using the thiophanate-methyl effect separately, is used in combination preventive effect and improves, and has reduced agricultural basis again.
Embodiment
Embodiment:
Further narrate the present invention below in conjunction with embodiment.
Embodiment 1, preparation 77% thiophanate-methyl Tebuconazole wetting powder 100kg
Tebuconazole 2kg (weight ratio 2%)
Thiophanate-methyl 75kg (weight ratio 75%)
NNO (dispersant) 11kg (weight ratio 2%)
Sodium alkyl benzene sulfonate (wetting agent) 2kg (weight ratio 5%)
Kaolin (filler) 10kg (weight ratio 16%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after airslide disintegrating mill is pulverized, mixes again, promptly obtains 77% thiophanate-methyl Tebuconazole wetting powder finished product.
800～1000 times of liquid of the preparation that is made into according to the above ratio about 80%, are better than single usefulness to the preventive effect of apple tree ring spot.
Embodiment 2, preparation 77% thiophanate-methyl Tebuconazole wetting powder 100kg
Tebuconazole 2kg (weight ratio 2%)
Thiophanate-methyl 75kg (weight ratio 75%)
NNO (dispersant) 2kg (weight ratio 2%)
Sodium alkyl benzene sulfonate (wetting agent) 5kg (weight ratio 5%)
Kaolin (filler) 16kg (weight ratio 16%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after airslide disintegrating mill is pulverized, mixes again, promptly obtains 77% thiophanate-methyl Tebuconazole wetting powder finished product.
800～1000 times of liquid of the preparation that is made into according to the above ratio about 80%, are better than single usefulness to the preventive effect of apple tree ring spot.
77% thiophanate-methyl Tebuconazole WP prevents and treats 7 days preventive effects (%) (Shaanxi Yang Ling) behind the ring rot of apple medicine
| Handle | I | II | III | IV | On average |
| 800 times | 90.12 | 94.52 | 92.96 | 93.65 | 93.06 |
| 900 times | 85.38 | 86.82 | 85.32 | 87.21 | 86.18 |
| 1000 times | 78.47 | 77.21 | 76.89 | 77.88 | 77.61 |
| 600 times of 50% thiophanate-methyl SC | 72.38 | 73.52 | 72.42 | 73.60 | 72.98 |
| 100 times of 40% asomate WP | 58.81 | 57.93 | 56.88 | 60.12 | 58.44 |
77% thiophanate-methyl Tebuconazole WP prevents and treats fortnight preventive effect (%) (Shaanxi Yang Ling) behind the ring rot of apple medicine
| Handle | I | II | III | IV | On average |
| 800 times | 86.11 | 87.17 | 88.04 | 89.05 | 87.59 |
| 900 times | 73.86 | 75.33 | 78.18 | 76.54 | 75.98 |
| 1000 times | 70.08 | 71.33 | 68.54 | 69.24 | 69.79 |
| 600 times of 50% thiophanate-methyl SC | 63.88 | 62.58 | 68.07 | 67.44 | 65.49 |
| 40% asomate WP100 doubly | 54.13 | 50.09 | 54.76 | 52.38 | 52.84 |
Embodiment 3: prepare 65% thiophanate-methyl Tebuconazole wetting powder 100kg
Tebuconazole 15kg (weight ratio 15%)
Thiophanate-methyl 50kg (weight ratio 50%)
NNO (dispersant) 15kg (weight ratio 15%)
Draw back powder (dispersant) 5kg (weight ratio 5%)
Alkyl benzene calcium sulfonate (wetting agent) 1kg (weight ratio 1%)
White carbon black (filler) 5kg (weight ratio 5%)
Diatomite (filler) 9kg (weight ratio 9%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after airslide disintegrating mill is pulverized, mixes again, promptly obtains 65% thiophanate-methyl Tebuconazole wetting powder finished product.
600～800 times of liquid of the preparation that is made into according to the above ratio more than 70%, are better than single usefulness to the preventive effect of watermelon powdery mildew.
65% thiophanate-methyl Tebuconazole wetting powder control watermelon powdery mildew preventive effect (Yixing, Jiangsu)
Embodiment 4: prepare 12% thiophanate-methyl Tebuconazole wetting powder 100kg
Tebuconazole 2kg (weight ratio 15%)
Thiophanate-methyl 10kg (weight ratio 15%)
Calcium lignosulfonate (dispersant) 15kg (weight ratio 15%)
Alkyl benzene calcium sulfonate (wetting agent) 3kg (weight ratio 3%)
Potter's clay (filler) 25kg (weight ratio 25%)
Precipitated calcium carbonate (filler) 45kg (weight ratio 45%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after airslide disintegrating mill is pulverized, mixes again, promptly obtains 12% thiophanate-methyl Tebuconazole wetting powder finished product.
400～600 times of liquid of the preparation that is made into according to the above ratio more than 70%, are better than single usefulness to the preventive effect of fruit white rot of grape.
12% thiophanate-methyl Tebuconazole wetting powder is prevented and treated fruit white rot of grape preventive effect (Changli, Hebei)
Embodiment 5: prepare 63% thiophanate-methyl tebuconazole suspension concentrates 100kg
Tebuconazole 8kg (weight ratio 8%)
Thiophanate-methyl 55kg (weight ratio 55%)
Polyoxyethylene nonylphenol ether (NP-9) (dispersion moisture agent) 8kg (weight ratio 8%)
Propane diols (antifreeze) 2kg (weight ratio 2%)
Xanthans (thickener) 0.9kg (weight ratio 0.9%)
Silicone defoaming agent (SAG612) 3kg (weight ratio 3%)
Water (filler) 23.1kg (weight ratio 23.1%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after sand mill grinds, mixes again, promptly obtains 63% thiophanate-methyl tebuconazole suspension concentrates finished product.
600～1000 times of liquid of the preparation that is made into according to the above ratio more than 70%, are better than single usefulness to the preventive effect of wheat scab, ring rot of apple.
63% thiophanate-methyl Tebuconazole SC prevents and treats behind the wheat scab medicine 30 days investigation preventive effect tables behind 7 days preventive effect (%) (Sichuan double fluid) secondary medicines
63% thiophanate-methyl tebuconazole suspension concentrates is prevented and treated 15 days preventive effects (%) (Yantai, Shandong) behind the ring rot of apple medicine
| Handle | I | II | III | IV | On average |
| 800 times | 92.12 | 90.51 | 90.90 | 95.60 | 92.28 |
| 900 times | 84.32 | 87.08 | 85.40 | 86.68 | 85.87 |
| 1000 times | 79.50 | 74.26 | 78.82 | 75.98 | 77.14 |
| 600 times of 50% thiophanate-methyl SC | 71.82 | 74.53 | 73.40 | 74.21 | 73.49 |
| 1500 times of 25% Tebuconazole EC | 80.81 | 82.93 | 82.41 | 80.12 | 81.56 |
Embodiment 6: prepare 60% thiophanate-methyl tebuconazole suspension concentrates 100kg
Tebuconazole 25kg (weight ratio 25%)
Thiophanate-methyl 35kg (weight ratio 35%)
Polyoxyethylene triphenyl phosphoric acid calcium (dispersion moisture agent) 11kg (weight ratio 11%)
Ethylene glycol (antifreeze) 1kg (weight ratio 1%)
Aluminium-magnesium silicate (thickener) 3kg (weight ratio 3%)
Silicone defoaming agent (Sag518) 0.6kg (weight ratio 0.6%)
White carbon black (filler) 2kg (weight ratio 2%)
Water (filler) 22.4kg (weight ratio 22.4%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after sand mill grinds, mixes again, promptly obtains 60% thiophanate-methyl tebuconazole suspension concentrates finished product.
600～700 times of liquid of the preparation that is made into according to the above ratio more than 80%, are better than single usefulness to the preventive effect of graw mold of tomato.
10 days preventive effect tables behind three medicines of 60% thiophanate-methyl Tebuconazole SC control graw mold of tomato preventive effect (new capital, Sichuan)
Embodiment 7: prepare 55% thiophanate-methyl tebuconazole suspension concentrates 100kg
Tebuconazole 20kg (weight ratio 20%)
Thiophanate-methyl 35kg (weight ratio 35%)
Negel (soprophor FL) (dispersion moisture agent) 8kg (weight ratio 8%)
Glycerine (antifreeze) 2kg (weight ratio 2%)
Xanthans (thickener) 4kg (weight ratio 4%)
Silicone defoaming agent (Sag722) 2kg (weight ratio 2%)
Water (filler) 29kg (weight ratio 29%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after sand mill grinds, mixes again, promptly obtains 55% thiophanate-methyl tebuconazole suspension concentrates finished product.
800～1000 times of liquid of the preparation that is made into according to the above ratio more than 70%, are better than single usefulness to the preventive effect of wheat scab disease.
55% thiophanate-methyl Tebuconazole SC prevents and treats citrus scab drug effect (Fujian Nan Jing) 10 days preventive effect tables behind the medicine for the third time
Embodiment 8: prepare 30% thiophanate-methyl tebuconazole suspension concentrates 100kg
Tebuconazole 15kg (weight ratio 15%)
Thiophanate-methyl 15kg (weight ratio 15%)
Alkyl naphthalene sulfonic acid calcium (soprophor FL) (dispersion moisture agent) 8kg (weight ratio 8%)
Propane diols (antifreeze) 2kg (weight ratio 2%)
Xanthans (thickener) 8kg (weight ratio 8%)
Silicone defoaming agent (Sag72) 0.2kg (weight ratio 0.2%)
White carbon black (filler) 10kg (weight ratio 10%)
Water (filler) 41.8kg (weight ratio 41.8%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after sand mill grinds, mixes again, promptly obtains 30% thiophanate-methyl tebuconazole suspension concentrates finished product.
800～1000 times of liquid of the suspending agent that is made into according to the above ratio more than 70%, are better than single usefulness to the preventive effect of sclerotinia rot of colza.
7 days preventive effect tables behind 30% thiophanate-methyl Tebuconazole SC control sclerotinia rot of colza preventive effect (Nantong) medicine
Embodiment 9: prepare 40% thiophanate-methyl tebuconazole suspension concentrates 100kg
Tebuconazole 3kg (weight ratio 3%)
Thiophanate-methyl 37kg (weight ratio 37%)
Negel (soprophor FL) (dispersion moisture agent) 6kg (weight ratio 6%)
Glycerine (antifreeze) 3kg (weight ratio 3%)
Aluminium-magnesium silicate (thickener) 5kg (weight ratio 5%)
Silicone defoaming agent (Sag22) 0.1kg (weight ratio 0.1%)
White carbon black (filler) 2kg (weight ratio 2%)
Water (filler) 43.9kg (weight ratio 43.9%)
The microbicide compositions that has synergistic effect by above-mentioned weight proportion weighing prepares raw material, and load weighted above-mentioned raw materials is fully mixed, and after sand mill grinds, mixes again, promptly obtains 40% thiophanate-methyl tebuconazole suspension concentrates finished product.
600～800 times of liquid of the suspending agent that is made into according to the above ratio more than 80%, are better than the conventional carbendazim medicament that uses to the preventive effect of rice sheath blight disease.
40% thiophanate-methyl Tebuconazole SC prevents and treats 5 days preventive effect tables behind rice sheath blight disease preventive effect (Jiangdu, the Jiangsu) medicine
Claims (3)
1, a kind of microbicide compositions with synergistic effect, it is characterized in that composition fungicide is made up of active ingredient thiophanate-methyl and Tebuconazole, composition fungicide prepares raw material weight percentage and is respectively Tebuconazole 2～25%, thiophanate-methyl 10～75%, auxiliary agent 3～25%, filler 10～70%; Microbicide compositions with synergistic effect is made wetting powder or suspending agent; The auxiliary agent of wetting powder is made up of dispersant 2～20% and wetting agent 1～5%; The auxiliary agent of suspending agent is by dispersion moisture agent 1～11%, antifreeze 1～3%, and thickener 0.9～8%, defoamer 0.1～3% is formed, and per distribution ratio is for accounting for composition fungicide weight percent proportioning.
2, according to the described microbicide compositions of claim 1 with synergistic effect, it is characterized in that dispersant adopts lignosulfonates, draws back a kind of or its mixture among powder, the NNO, dispersion moisture agent adopts a kind of or its mixture in polyoxyethylene triphenylethylene phosphenylic acid salt, alkylnaphthalene sulfonate, the alkylphenol polyoxyethylene; Wetting agent adopts sodium alkyl benzene sulfonate or alkyl benzene calcium sulfonate; Antifreeze adopts a kind of in propane diols, glycerine, the ethylene glycol; Thickener adopts xanthans or aluminium-magnesium silicate; Defoamer adopts silicone defoaming agent; Filler adopts a kind of or its mixture in precipitated calcium carbonate, potter's clay, kaolin, diatomite, the water.
3, the described microbicide compositions with synergistic effect of claim 1 is used in control fruit tree, grape, vegetables, watermelon, wheat, all kinds of diseases of paddy rice.
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| CN1943350B (en) * | 2006-11-07 | 2011-08-31 | 深圳诺普信农化股份有限公司 | Composition with sterilizing function containing difenoconazole and thiophanate-methyl |
| WO2009098230A2 (en) * | 2008-02-05 | 2009-08-13 | Basf Se | Pesticidal mixtures |
| CN101999385A (en) * | 2010-12-05 | 2011-04-06 | 弥华锋 | Thiophanate methyl- and tebuconazole-containing water dispersible granules |
| CN103283746B (en) * | 2013-04-28 | 2015-10-28 | 山东省果树研究所 | One planting fruit-trees, forest trunk disease therapeutic agent |
| US9364001B2 (en) | 2013-11-07 | 2016-06-14 | Adama Makhteshim Ltd. | Quaternary fungicidal mixture |
| BR102013030596A2 (en) * | 2013-11-28 | 2015-09-22 | Rotam Agrochem Int Co Ltd | method of treating fungicidal infections, fungicidal compositions and their use |
| CN103783057B (en) * | 2014-01-26 | 2016-04-06 | 上海艳紫化工科技有限公司 | Thiophanate-methyl and the composite agricultural chemicals suspension agent of Tebuconazole |
| CN103891745A (en) * | 2014-03-28 | 2014-07-02 | 海南力智生物工程有限责任公司 | Germicide and application thereof |
| CN106922712A (en) * | 2015-12-30 | 2017-07-07 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
| CN106922701A (en) * | 2015-12-30 | 2017-07-07 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
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| Chemical control of angular leaf spot of common bean. Sartorato, Aloisio, Rava, Carlos A.Summa Phytopathologica,Vol.29 No.2. 2003 |
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