CN100377738C - Medicine and food dual purpose Chinese medicine for preventing and treating wind cold diarrhea and its manufacturing method - Google Patents

Medicine and food dual purpose Chinese medicine for preventing and treating wind cold diarrhea and its manufacturing method Download PDF

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CN100377738C
CN100377738C CNB2005101364010A CN200510136401A CN100377738C CN 100377738 C CN100377738 C CN 100377738C CN B2005101364010 A CNB2005101364010 A CN B2005101364010A CN 200510136401 A CN200510136401 A CN 200510136401A CN 100377738 C CN100377738 C CN 100377738C
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chinese medicine
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medicinal residues
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CN1824230A (en
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颜怀伟
颜怀玮
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Abstract

The present invention relates to a traditional Chinese medicine and a making method thereof, wherein the traditional Chinese medicine is used as both a medicine and food for preventing and treating cold diarrhea, and is made from traditional Chinese medicines as both a medicine and food, such as cassia bark, radish seed, villous amomun fruit, wrinkled gianthyssop herb, purple common perilla, galingale, common yam rhizome, haricot bean, gordon euryale seed, semen nelumbinis, pepper, Chinese date, pricklyash peel, sour orange, siberian solomonseal rhizome, etc. The present invention has the advantages of low production cost, no environmental pollution, no difference in people and age, good mouth feel, small dosage, affirmative effect and easy acceptance by patients. The combined medicinal materials of the traditional Chinese medicine and the medicine properties have the functions of function protection and coordination to the heart, the lungs, the spleen, the kidneys, etc., and embody the whole concept and advantages of the traditional Chinese medicine sufficiently so as to complete medicine effects and functions to treat both a manifestation cause and a root cause of a disease, reaching a very high bourn that the whole medicine properties of the traditional Chinese medicines tend to be mild and raise medicine effect mutually. Furthermore, as all the medicinal materials are both official medicines and food, the effect is affirmative without toxic or side effect. The present invention is suitable for any crowd with wide service range; the used variety and the functions of the medicines are simple and clear; prescriptions are flexible and various and adapt to various states of illness with suitable medication selection; the particular content and the application range of the determination of treatment based on different symptoms and signs of the traditional Chinese medicine and pharmacy are widened.

Description

Control diarrhea due to wind-cold medicinal and edible Chinese medicine and manufacture method
Chinese medicine and western modern medicine disease preventing and treating theory one significantly difference be that the former does not rest on analysis to the concrete cause of disease to pathological knowledge, show the nonantagonistic latter and then be antagonism, that is the former emphasizes is human body integral and the ability that how improves the antagonism disease from integral body, the latter then is that " sitting in the right seat " is as what microorganism, malnutrition or surplus, poisonous and harmful substance (comprising medicine) and effect etc. cause any disease, though theoretic dispute is very big, even opposition and antagonism, whom shows under a lot of situations whom does not persuade, mutual contradiction or do not have public opinion even, undisputable fact really but they can both be cured the disease and/or reach a cure, this also proved human to medicine especially in, cognitive level and ability between western modern medicine is mutual are also very limited, and arbitrarily in the dogmatize about, the western modern medicine theory who to whose mistake, can not declare that more which is right and which is wrong, because both sides do not have enough conclusive evidences to prove that the other side is wrong, so do not meet the view of science, so should advocate the pardon scientific research of promptly taking facts as the basis and deepen continuously progressively gets and improves relevant theoretical dispute clear with practice and argue, thereby in constantly enriching, the theoretical treasure-house of western modern medicine, make the two can both more effectively be human good health and a long life service, but not argue for arguement, even be negative arbitrarily even attack the other side, not science and responsible attitude and behavior because do like this by lack of evidence ground to argue, all be unfavorable for ensureing and developing human medical and health care system.
At present this class disease of control in, Western medicine product substantially all be lay particular stress on treat and effect single, though also can solve some problems but ignored globality and balance and the rapport and the importance of relevant organ dysfunction, and easily therefore cover other problem or even question of substance, cause more serious consequence on the contrary; Chinese medicine is normal to be used rare or/and contain the animality medical material of hormone and relevant various toxicity, side effects, makes its resource and service group limited, and not only side effect is big and very easy formation dependency and very expensive, and Western medicine is no exception; In no matter the more important thing is, the all rarer officinal food dual purpose product of Western medicine, this is to forbid unauthorized medicine to use food (comprising health product) in any form because consider all to make laws from drug safety in China and a lot of countries and regions, otherwise investigate civil and even criminal responsibility in accordance with the law, and that disease reaches the degree of essential treatment is very serious, say on the clinical meaning often to have missed the optimal treatment period and often be difficult to and cure or increase greatly treatment and cure difficulty, medical expense is also very high, many patients and family are difficult to bear, especially developing country is even more serious, the ratio that accounts for total population as China peasant is up to there not being medical care insurance more than 70% substantially, also has the expensive medical fee of same very important laid-off worker and indigent family's financial insolvency, let alone puted prevention first, even if also just can sell medicine as the U.S. because of the prescription drugs pharmacy that must the doctor prescribes in developed country and area, otherwise it is illegal, consumer then must pay expenses such as high prescription takes and surpass medicine valency itself outward, and nonprescription drugs, health food is that the dietotherapeutic product then need not prescription and expensive expense thereof, has alleviated consumer's financial burden greatly and made to buy to consume simple and direct and increase purchasing power, fulfill thereby making puts prevention first.Therefore unique legal effectively, economically feasible, to put prevention first, prevent and treat the scheme of taking into account just can only be screening, combination and design relevant new departure and new product in view of the above in legal dietotherapeutic medicine scope, because of such product could really accomplish good and cheap and meet the inveteracy consumption habit of consumer's " Diet cures more than the doctors ", consumer channel is unblocked, service group is extensive, its disease preventing and treating function and curative effect, safety and crowd's general applicability could also must gain public acceptance and serial relevant law such as state food health legislation is approved and protect.Total be exactly the present invention at prior art not enough, for one for solve an above-mentioned serial difficult problem inventive concept the control diarrhea due to wind-cold medicinal and edible Chinese medicine and the manufacture method that design, its health that adopts officinal food promulgated by the ministries or commissions of the Central Government main Chinese medicine principle and function, advantage dual-purpose and parts by weight of traditional Chinese medicines and the property of medicine and foundation are described below.
Hot, the kind promoting blood circulation of Cortex Cinnamomi, stomachache deficiency and coldness, temperature compensation can get.Cortex Cinnamomi acrid-sweet flavor, extremely hot in nature have the effect of YANG invigorating dispersing cold for relieving pain, are good at warm promoting blood circulation, are applicable to insufficiency of kidney-YANG, aversion to cold and cold limbs, chills and pain of the waist and kness, women's cold in blood amenorrhea, and diseases such as the coldness and pain in the epigastrium of deficiency and coldness, cold diarrhea, all can play the effect of temperature compensation.
Semen Raphani suffering, the therapeutic method to keep the adverse QI flowing downwards of breathing with cough, fall wall towards wall, distension cancellation.Semen Raphani acrid-sweet flavor, property are put down, and its sending down the abnormal ascending QI removes expectorant, the long-pending strength that helps digestion is very big, so have the cough and asthma of excess pathogen and diseases such as the intestines and stomach accumulation of food in the stomach and intes tine due to indigestion, distension and fullness of the chest and abdomen or stomachache dysentery all can eliminate to lung.
Fructus Amomi is warm in nature, nourishing the stomach feed, pain relieving are antiabortive, regulating the flow of vital energy brokenly stagnates.Fructus Amomi acrid in the mouth, warm in nature, the appetite stimulator that can whet the appetite, be applicable to stagnation of QI in spleen and stomach, appetite do not open, and dyspeptic vomiting have loose bowels, and control chest and abdomen swelling and pain, control that the stagnation of QI must not circulate and the frequent fetal movement that causes.These all are the effects that has the removing mass of regulating the flow of vital energy to stagnate because of it.
The hot temperature of Herba Pogostemonis, can preventing or arresting vomiting tell, dispersing wind-cold, cholera be main.Herba Pogostemonis acrid in the mouth, slightly warm in nature, the effect that removing dampness by means of aromatics is arranged, regulate the flow of vital energy and deliver, thus can tell by preventing or arresting vomiting, also can dispersing wind-cold.This product cures mainly and has been subjected to heat-damp in summer, incoordination between the spleen and stomach summer, diseases such as vomiting and dirarrhea occur.The leaves of pulse plants disorderly is the chaotic for the moment vomiting and dirarrhea that causes of gas pure and impure in the human body, summer pilosity.
All gas, elimination distension are down delivered, obstructed to Folium Perillae acrid in the mouth, wind and cold.Folium Perillae acrid in the mouth, warm in nature, diseases such as leaf is delivered the dispersing wind and cold effect, can be controlled anemofrigid cold, aversion to cold is lossless, nasal obstruction cough, stalk has the sending down the abnormal ascending QI effect, can eliminate the distension and fullness of the chest and abdomen that gas does not circulate, stalk has antiabortive effect concurrently, can control diseases such as flatulence period of pregnancy Ai gas uncomfortable in chest, use a large amount of (10 parts) to fry in shallow oil the soup clothes again, can control the poisoning of ichthyophagy Eriocheir sinensis, chest and abdomen swelling and pain, vomiting and have loose bowels.
Rhizoma Alpiniae Officinarum is hot in nature, hematochezia warming middle-JIAO, the convulsion leaves of pulse plants disorderly, food and drink can attack.Rhizoma Alpiniae Officinarum acrid in the mouth, hot in nature, the effect that has the warming the middle warmer and descending qi pain relieving to help digestion, kind the catch cold cold type of pain, vomit and diarrhoea convulsion and food and drink of stomach of controlling do not disappear etc.This product seed be called Fructus Galangae, performance function identical, be good at the alcoholic intoxication that helps digestion.
Rhizoma Dioscoreae (potato) Gan Wen, reason spleen antidiarrheal, kidney tonifying invigorating middle warmer, all void can be controlled.Potato sweet in the mouth, warm in nature has tonifying the spleen and stomach, stopping leak to rush down effect with nourishing kidney, is applicable to weakness of the spleen and stomach, inappetence, the chronic dysentery of having loose bowels and the something lost of suffering from a deficiency of the kidney. diseases such as essence, leukorrhagia, and control and quench one's thirst, all can treat the insufficient disease of weakness.
Seem Lablab Album tepor, convulsion vomiting and diarrhoea, the therapeutic method to keep the adverse QI flowing downwards and in, alcoholism can change.Seem Lablab Album sweet in the mouth, slightly warm in nature have the invigorating the spleen for eliminating dampness effect, be applicable to the heat-damp in summer disorder of the spleen and stomach caused by internal damage so that in gas discord, cause vomiting and dirarrhea, the anxious diseases such as (convulsions) of Calf muscle contraction, and control that the women is insufficiency of the spleen a wet leucorrhea disease.Give birth to and grind the effect that strand juice clothes have heat-clearing and toxic substances removing again, but and alcoholic intoxication.
Semen Euryales sweet in the mouth, the beneficial vital essence of energy, waist knee joint epidemic disease pain, all main wet spleen.Semen Euryales sweet-puckery flavor, property are put down, and the effect of the kidney invigorating and essence nourishing is arranged, and can control the waist knee joint epidemic disease pain of suffering from a deficiency of the kidney, and the energy removing dampness, so also effective to arthralgia chiefly caused by damp pathogen arthralgia.This product more has the effect of controlling nocturnal emission with astringent drugs and invigorating the spleen to arrest diarrhea, the seminal emission that can only suffer from a deficiency of the kidney and women's leucorrhea and insufficiency of the spleen chronic dysentery etc. of having loose bowels.This product is the Gorgon fruit.
Semen Nelumbinis sweet in the mouth, spleen invigorating are managed stomach, antidiarrheal arresting seminal emission, are cleared away heart-fire and foster the spirit of nobility.Semen Nelumbinis sweet in the mouth, property are flat, have that tonifying the spleen and stomach, stopping leak rush down, an effect of kidney tonifying arresting seminal emission and benefiting heart-QI, are applicable to insufficiency of the spleen chronic dysentery of having loose bowels, the emission of suffering from a deficiency of the kidney and diseases such as women's leukorrhagia and palpitation and insomnia.Plumula Nelumbinis is embryo tooth, the bitter in the mouth, cold in nature of this product, and the effect of the heat that clears away heart-fire is arranged, and can control the epidemic febrile disease pathogenic heat pericardium that caves in, and the coma of appearance, says paste etc.
Fructus Piperis acrid in the mouth, trusted subordinate's cold type of pain, therapeutic method to keep the adverse QI flowing downwards warming middle-JIAO, fall benefit and may use.Fructus Piperis acrid in the mouth, hot in nature has the effect of warming stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, can control that breast abdomen cold is had a pain and gastrofrigid vomiting or dysentery, injury from falling down etc. also can be used.
Fructus Jujubae sweet in the mouth, mediation hundred medicines, QI invigorating are supported spleen, fullness in the epigastrium and abdomen is not chewed.Fructus Jujubae sweet in the mouth, warm in nature, function are in harmonious proportion writes a prescription, and the effect of QI invigorating spleen reinforcing is arranged, and can control weakness of the spleen and stomach, diseases such as the chronic dysentery of having loose bowels and cardiopalmus stomachache.This product is a tonics.Help humidogene expectorant easily, therefore the distension in the heart that is caused by phlegm-damp is not obeyed.
Pericarpium Zanthoxyli is hot, uncharm by the parasite killing of trembling with fear, make eye bright, temperature and not violent.The Pericarpium Zanthoxyli acrid in the mouth is warm in nature, the warming the spleen stomach is arranged, by cold-damp, parasiticidal effect, be applicable to diseases such as breast abdomen cold type of pain or dysentery stomachache and vomiting ascarid, fiercely can also not make eye bright so it is warm in nature.
CitrusaurantiumL.Var.amara Engl. regulate the flow of vital energy the chest stuffiness relieving, the appetizing preventing or arresting vomiting.Cure mainly uncomfortable in chestly do not relax, anorexia, abdominal distention, vomiting are felt sick etc.
The Rhizoma Polygonati sweet in the mouth, can pacify internal organs, five kinds of strain and seven kinds of impairment, the big benefit of this medicine.Rhizoma Polygonati sweet in the mouth, property are flat, the spleen reinforcing lung moistening, and it is sick as weakness of the spleen and stomach, cough due to deficiency of the lung and disease such as quench one's thirst to control the deficient impairment caused by overstrain of internal organs.Five kinds of strain and seven kinds of impairment: hepatic asthenia, the impairment of the heart caused by overstrain, the impairment of the spleen due to overstrain, impairment of the kidney caused by overstrain; The big full impairment of the spleen, rage QI rising in reverse order impairing the liver, powerful weight lifting sitting wetland are impairment of the kidney, cold physique drink cold injury lung, sorrow are pondered over sad, wind and rain abnormal weather changes being apt to injure configuration of the body, big fear does not save the impairment of mentality.
Product of the present invention is by legal dietotherapeutic Chinese crude drug Cortex Cinnamomi 0.3-1 part, Semen Raphani 2-4 part, Fructus Amomi 0.5-1.5 part, Herba Pogostemonis 1.5-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Rhizoma Dioscoreae 3-6 part, Seem Lablab Album 3-5 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Piperis 0.3-1 part, Fructus Jujubae 3-10 part, Pericarpium Zanthoxyli 0.5-3 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Rhizoma Polygonati 3-5 part are that raw material of Chinese medicine is formed.
The manufacture method of product of the present invention is as follows;
A. decoction pieces type Chinese crude drug Cortex Cinnamomi 0.3-1 part, Semen Raphani 2-4 part, Fructus Amomi 0.5-1.5 part are on the waiting list in the choosing of raw material Chinese medicine, Herba Pogostemonis 1.5-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Rhizoma Dioscoreae 3-6 part, Seem Lablab Album 3-5 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Piperis 0.3-1 part, Fructus Jujubae 3-10 part, Pericarpium Zanthoxyli 0.5-3 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Rhizoma Polygonati 3-5 part joins in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage (solubilized many be insoluble in the material of water and significantly improve drug effect) and adds the dilution of room temperature drinking water that to make ethanol (dense) degree be that alcohol content is the organic mixed solvent (mixed solution for extraction object Chinese medicinal ingredients material different liquids still can be considered solvent) with inorganic two kinds of solvent compositions of the sterilization type of 55-75% (V/V is a volume ratio), and alcoholic strength is lower than 55% or be higher than 75% equal difficulty and reach optimum extraction and sterilization effect;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of ethanol boiling point (to reduce evaporation of water and distillation as far as possible) vaporization ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, ensure that extracting solution utmost point low organic solvent is the high-quality of alcohol content, used cooling water extracts water as preheating, these measure and ensures the low energy consumption of production and product, low water consumption, low-cost, and avoided the pollution of organic solvent to environment and product, the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container room temperature (because of contain the few breeding of bacterium limited guarantee not putrid and deteriorated) soaked Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded to add (height) warm extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, add simultaneously (height) temperature (so the time contain bacterium may be than d for high) lower the temperature slowly naturally after 3-5 minute to boiling that (summer high temperature was lowered the temperature and can suitably be aided with the room temperature water-cooled too slowly in about 20-30 minute, the same recyclable described preheating water of c of incorporating into of cooling water) continues stripping and energy-saving and water-saving to 60-70 ℃ in order to pharmaceutical compositions, extract and must high temperature could propose and low temperature is not carried most material composition, and make and heat rapidly and evenly, reduce material damage and loss, with further raising drug effect and recovery rate, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, the medicinal residues that discard behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed are the acyclic dirts of agricultural soil high-quality fertilizer of returning crop stocks to the field, and medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product of the present invention is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, lactose is added Chinese medicine extraction liquid, is the solution dry matter content that concentration promotes and to be 35-40%, be spray dried into water content and get product below 3%, host or additive as food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP; Any shape such as the sheet of compacting (lactose is compression moulding very easily) one-tenth 0.2-0.4 gram, grain, ball as food, nutriment, health product and medicine, are advised oral every day 2-3 time, each 0.4-0.8 gram, need not the branch of crowd and dosage.
The purposes of product of the present invention, usage and consumption: as food, nutriment, health product and medicine, oral every day 2-3 time, each 0.4-0.8 restrain, and need not the branch of crowd and dosage; As the host or the additive of food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP.
Embodiment:
1, drinks 0.3 part of sheet type Chinese crude drug Cortex Cinnamomi, 2 parts of Semen Raphanis, 0.5 part of Fructus Amomi, 1.5 parts of Herba Pogostemoniss, 1 part of Folium Perillae, 0.8 part of Rhizoma Alpiniae Officinarum, 3 parts of Rhizoma Dioscoreaes, 3 parts in Seem Lablab Album, 2 parts of Semen Euryaless, 2 parts in Semen Nelumbinis, 0.3 part in Fructus Piperis, 3 parts in Fructus Jujubae, 0.5 part in Pericarpium Zanthoxyli, 1 part of CitrusaurantiumL.Var.amara Engl., 3 parts of Rhizoma Polygonatis, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the daily life health food that puts prevention first.
2, drink 0.5 part of sheet type Chinese crude drug Cortex Cinnamomi, 3 parts of Semen Raphanis, 1 part of Fructus Amomi, 2 parts of Herba Pogostemoniss, 2 parts of Folium Perillaes, 1 part of Rhizoma Alpiniae Officinarum, 4 parts of Rhizoma Dioscoreaes, 4 parts in Seem Lablab Album, 2 parts of Semen Euryaless, 3 parts in Semen Nelumbinis, 0.6 part in Fructus Piperis, 5 parts in Fructus Jujubae, 1 part in Pericarpium Zanthoxyli, 2 parts of CitrusaurantiumL.Var.amara Engl.s, Rhizoma Polygonati is a raw material of Chinese medicine for 4 parts, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the light patient of the their early stage or the state of an illness.
3, drink 1 part of sheet type Chinese crude drug Cortex Cinnamomi, 4 parts of Semen Raphanis, 1.5 parts of Fructus Amomis, 3 parts of Herba Pogostemoniss, 3 parts of Folium Perillaes, 1.5 parts of Rhizoma Alpiniae Officinarum, 6 parts of Rhizoma Dioscoreaes, 5 parts in Seem Lablab Album, 3 parts of Semen Euryaless, 4 parts in Semen Nelumbinis, 1 part in Fructus Piperis, 10 parts in Fructus Jujubae, 3 parts in Pericarpium Zanthoxyli, 2 parts of CitrusaurantiumL.Var.amara Engl.s, Rhizoma Polygonati is a raw material of Chinese medicine for 5 parts, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, the Any shape such as sheet, grain, ball that product of the present invention are pressed into 0.2-0.4 gram get product.Be mainly used in the long or heavier patient of the state of an illness of the course of disease.
Supplementary copy inventive principle and advantage are as follows:
1, the present invention adopts the low lactose of water absorption to do complexion changed and easy preservation that filler can reduce duration of storage, so storage life is that the commodity shelf life is long, economic worth is high, and constitute most crowds with little sweet taste of lactose and like " little sweet " the popular taste products of eating and easily be accepted, so service face and service group are the most extensive, its society and economic benefit are also just apparent naturally.
2; the property of medicine of Chinese prescription medical material is with flat; Wen Weizhu; also take into account simultaneously and liver (gallbladder); relevant other organ of order after one's own heart; lung; spleen; the protection of the function of kidney and coordination; Chinese medicine organic conception and advantage have been demonstrated fully; make drug effect and function more comprehensive and mark; this double controlling; realized that Chinese medicine property of medicine general inclination is in gentle and promote the high boundary of drug effect mutually; and because of the legal dietotherapeutic of all medical materials; effect certainly and do not have a toxic and side effects; be suitable for any crowd and serve wide, these just the present invention to the imbody of the wide main advantages of Chinese medicine adaptive surface.
3, medicine variety and function all are legal medicine-food two-purposes and simple and clear and do not have a dispute, and the multiple state of an illness of prescription adaptation versatile and flexible and select medication properer has been opened up out Chinese medicine and debated disease and execute tool body content and range of application.
4, all medical materials all are conventional varieties and do not have hormone and toxic and side effects, so quality, the source is secure and aboundresources is cheap, product of the present invention can be consumed by vast general patient because of no patient crowd's branch event and obtain and afford to consume, and the realization new and high technology is served lofty aim for the most numerous common people.
5, innovate organic and inorganic mixed solvent and extract at room temperature and reclaim organic solvent and recycle molten and water-soluble substances and energy-conservation joint (cooling) water of Extraction oil with being beneficial to synchronously high-quality and high recovery rate, again with inorganic solvent and room temperature and high temperature combined extractive technique, scheme and technology, ensured extraction overall process asepticize, can carry substantially many to the greatest extent be insoluble in water or be insoluble in oil material and significantly improve drug effect and extract quality and content, and extraction ratio from, with short production cycle, energy-saving and water-saving, product cost is low, do not have (organic solvent) and pollute, its serial comprehensive advantage is traditional decocting and single with organic solvent or water or some other is because of expensive, highly difficult, the product of receiving single (fact proved and the generally acknowledged both at home and abroad compound composition extract of Chinese medicine than single composition extract good effect, this was exactly the essence and the inherent feature place of Chinese medicine originally and was determined by it), recovery rate low and short-term even long duration are difficult to that so-called modern Chinese medicine extractive technique that penetration and promotion uses is difficult to mention in the same breath.
6, become the favorable factor of the defective of China and Asia average 80% above population Lactose enzyme indigestibility absorption for want of (as milk) lactose into disease preventing and treating, can significantly slow down the medicine slow release speed and avoid taking the very big and beyond affordability historic difficult problem of traditional decocting Chinese medicine dose because adopt lactose to replace the starch easily digested and assimilated and dextrin to make adsorbent, adhesive and filler, thereby significantly prolong the efficacy of a drug persistent period and improve curative effect and possible medicine irritation is relieved to bottom line.
More than these also are the great novelty and the practicality of the legal approval of Patent Law.
Test method, data and presentation of results and prompting: disease that product of the present invention is controlled belongs to common frdquently encountered disease so tool is extensively representative, experimenter's voluntary participation.Product of the present invention because of good effect and have no side effect and crowd's branch, so treatment cycle is short and cure rate is high, make test be easy to just satisfactorily be finished, now further be explained as follows (only for reference) with allow keeping in Patent Law about situation under the prerequisite of necessary KNOW-HOW and business secret and please understand: it is 2 groups that totally 40 of the test patients at different sexes, age, 20 people are divided into for one group: one group with product of the present invention and usage and dosage prevent and treat, one group of not medication compares; Test number and time on test reach the equal tool statistical significance of 2 first quarter moons, test number and experimental period so suitable representativeness and credibility are arranged.The result is as follows: none the routine state of an illness of test group personnel with product of the present invention is deepened, and 5 people's no changes are arranged, and has 15 people to improve; The state of an illness promptly was significantly improved than the lighter the same day; The matched group experimenter finds the state of an illness person of increasing the weight of 16 people, and 4 people feel no significant change, the remarkable improver of none state of an illness on the same day.Prompting: the state of an illness does not deepen just to prove absolutely that the state of an illness is controlled, is that product of the present invention is effective that the direction that the state of an illness improvement explanation state of an illness is become better reverses, is that product efficacy of the present invention is remarkable.
To sum up state, raw material of the present invention, product and method belong to a total inventive concept, economic environmental protection good effect, be suitable for the crowd and market is all very wide, helpfulness and the degree of association are also very high.

Claims (2)

1. prevent and treat the manufacture method of diarrhea due to wind-cold medicinal and edible Chinese medicine, it is characterized in that:
A. drink sheet type Chinese crude drug Cortex Cinnamomi 0.3-1 part, Semen Raphani 2-4 part, Fructus Amomi 0.5-1.5 part, Herba Pogostemonis 1.5-3 part, Folium Perillae 1-3 part, Rhizoma Alpiniae Officinarum 0.8-1.5 part, Rhizoma Dioscoreae 3-6 part, Seem Lablab Album 3-5 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Piperis 0.3-1 part, Fructus Jujubae 3-10 part, Pericarpium Zanthoxyli 0.5-3 part, CitrusaurantiumL.Var.amara Engl. 1-2 part, Rhizoma Polygonati 3-5 part join in the nonmetallic surface container of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage and is added the dilution of room temperature drinking water and makes the organic and inorganic mixed solvent that alcohol content is 55-75%V/V;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, heater accurately is heated to 78-80 ℃ of vaporization of ethanol boiling point ethanol respectively with medicinal residues and medicinal liquid, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, used cooling water extracts water as preheating, and the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container soak at room temperature Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. water is proceeded high temperature extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, being warmed to boiling simultaneously slowly lowered the temperature about 20-30 minute to 60-70 ℃ after 3-5 minute naturally, the summer high temperature cooling suitably is aided with the room temperature water-cooled too slowly, cooling water reclaims incorporates the described preheating water of c into, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, discard medicinal residues behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, and lactose is added Chinese medicine extraction liquid, is the solution dry matter content that concentration promotes and to be 35-40%, be spray dried into water content below 3% promptly.
2. prevent and treat the product of the manufacture method manufacturing of diarrhea due to wind-cold medicinal and edible Chinese medicine according to claim 1.
CNB2005101364010A 2005-12-29 2005-12-29 Medicine and food dual purpose Chinese medicine for preventing and treating wind cold diarrhea and its manufacturing method Expired - Fee Related CN100377738C (en)

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CN106491748A (en) * 2016-12-17 2017-03-15 郑州郑先医药科技有限公司 A kind of treat Chinese and western medicinal composition of chronic diarrhea and preparation method thereof
CN108432922B (en) * 2018-04-17 2021-10-22 辽宁和泉堂药业有限公司 Honeysuckle and chrysanthemum tea for clearing pestilence and removing epidemic disease

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CN1100905A (en) * 1993-10-04 1995-04-05 高福星 Flavorous nutrient seasoning and health-keeping medicine
CN1145193A (en) * 1995-09-13 1997-03-19 美国鸿利国际公司北京办事处 Powdered compound condiment and its prepn. method
CN1183289A (en) * 1996-11-26 1998-06-03 许君寿 Instant particle for gastrosis
CN1302645A (en) * 2000-12-22 2001-07-11 张志祥 Medical capsule for invigorating function of spleen and its preparing process
CN1695675A (en) * 2005-05-19 2005-11-16 李春光 Chinese traditional medicine for treating diarrhea of infant and preparation method

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CN1100905A (en) * 1993-10-04 1995-04-05 高福星 Flavorous nutrient seasoning and health-keeping medicine
CN1145193A (en) * 1995-09-13 1997-03-19 美国鸿利国际公司北京办事处 Powdered compound condiment and its prepn. method
CN1183289A (en) * 1996-11-26 1998-06-03 许君寿 Instant particle for gastrosis
CN1302645A (en) * 2000-12-22 2001-07-11 张志祥 Medical capsule for invigorating function of spleen and its preparing process
CN1695675A (en) * 2005-05-19 2005-11-16 李春光 Chinese traditional medicine for treating diarrhea of infant and preparation method

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