CN100394974C - Medicine and food dual purpose Chinese medicinal nutritive product for preventing and treating limp lumbus and knees and its manufacturing method - Google Patents

Medicine and food dual purpose Chinese medicinal nutritive product for preventing and treating limp lumbus and knees and its manufacturing method Download PDF

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CN100394974C
CN100394974C CNB2005101364364A CN200510136436A CN100394974C CN 100394974 C CN100394974 C CN 100394974C CN B2005101364364 A CNB2005101364364 A CN B2005101364364A CN 200510136436 A CN200510136436 A CN 200510136436A CN 100394974 C CN100394974 C CN 100394974C
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medicinal residues
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CN1824221A (en
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颜怀伟
颜怀玮
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Abstract

The present invention relates to a traditional Chinese medicine nutrition product used as both medicine and food for preventing and treating soreness and weakness of waist and knees, and a making method thereof. The traditional Chinese medicine product is prepared from traditional Chinese medicines officially used as both medicine and food: common yam rhizome, common floweringquince fruit, gordon euryale seed, coix seed, palmleaf raspberry fruit, etc. The present invention has the advantages of low production cost, no environmental pollution, no difference in people and age, good mouth feel, small dosage, good effect and easy acceptance by patients. The combined medicinal materials of the traditional Chinese medicine and the medicine properties have the functions of protection and coordination to the heart, the lungs, the spleen and the kidneys, and embody the whole concept and advantages of the traditional Chinese medicine sufficiently so as to complete medicine effects and functions to treat both a manifestation cause and a root cause of a disease and realize a very high bourn that the whole medicine properties of the traditional Chinese medicines tend to be mild and raise medicine effect mutually. Furthermore, as all the medicinal materials are both official medicines and food, the effect is affirmative without toxic or side effect. The present invention is suitable for any crowd with wide service range; the used variety and the functions of the medicines are simple and clear; formulas are flexible and various and adapt to various states of illness with suitable medication selection; the particular content and the application range of the determination of treatment based on different symptoms and signs of the traditional Chinese medicine and pharmacy are widened.

Description

The application of a kind of compositions in the medicine of preparation control soreness of the waist and knees
Chinese medicine and western modern medicine disease preventing and treating theory one significantly difference be that the former does not rest on analysis to the concrete cause of disease to pathological knowledge, show the nonantagonistic latter and then be antagonism, that is the former emphasizes is human body integral and the ability that how improves the antagonism disease from integral body, the latter then is that " sitting in the right seat " is as what microorganism, nutrient, poisonous and harmful substance (comprising medicine) and effect etc. cause any disease, though theoretic dispute is very big, even opposition and antagonism, whom shows under a lot of situations whom does not persuade, mutual contradiction or do not have public opinion even, undisputable fact really but they can both be cured the disease and/or reach a cure, this also proved human to medicine especially in, cognitive level and ability between western modern medicine is mutual are also very limited, and arbitrarily in the dogmatize about, the western modern medicine theory who to whose mistake, can not declare that more which is right and which is wrong, because both sides do not have enough conclusive evidences to prove that the other side is wrong, so do not meet the view of science, so should advocate the pardon scientific research of promptly taking facts as the basis and deepen continuously progressively gets and improves relevant theoretical dispute clear with practice and argue, thereby in constantly enriching, the theoretical treasure-house of western modern medicine, make the two can both more effectively be human good health and a long life service, but not argue for arguement, even be negative arbitrarily even attack the other side, not science and responsible attitude and behavior because do like this by lack of evidence ground to argue, all be unfavorable for the guarantee and the development of human medical and health care system; Chinese medicine is that with another remarkable difference of western modern medicine disease preventing and treating the cycle of the former general treatment disease is generally good than the latter than the long prognosis slow but after curing of promptly producing effects of the latter, this and its integrity attribute is closely related so do not have contradiction in itself and can yet be regarded as a good explanation with aforesaid first difference, therefore often to be used to prevent and treat many chronic disease western modern medicines then often opposite for Chinese medicine, and the present invention then can yet be regarded as and belongs to one of case of utilizing this generic attribute of Chinese medicine and characteristics.
Soreness of the waist and knees is person in middle and old age's commonly encountered diseases and frequently-occurring disease, particularly the China and even the whole world have faced aging society, and along with modern society's work and the quickening of rhythm of life and the increasing of pressure, many adolescent also too greatly obviously present the situation that becomes younger because of physical and energy overdraw, can recover and recover very fast voluntarily, but this is temporary improvement, do not influence ill and character, because of Here it is the early warning of body and the beginning of disease, even weight person's soreness of the waist and knees is to the awake difficult degree of sleeping and reaching several months a couple of days of pain, very big to healthy even life and security threat, therefore be worth providing for a rainy day, must take seriously and conscientiously control, can't be because of being that the careless or self-confident youth of chronic disease is not cared about in the least.
At present this class disease of control in, Western medicine product substantially all are to lay particular stress on to treat and function singleness, some Chinese medicines also use the animality medical material, well-known be so that many animality herb resources are few very expensive and unfavorable rare precious animal protection and ecological balance construction, and these products also often contain various hormones and relevant various side effect because of the reason of animality medical material etc., make its service group limited; It is just more common that Western medicine contains hormone, and what have is exactly single or the combination hormone purely, and not only side effect is big and very easy formation dependency; No matter, the all rarer officinal food dual purpose product of Western medicine, this is to forbid unauthorized medicine to use food (comprising health product) in any form because consider all to make laws from drug safety in China and a lot of countries and regions, otherwise call to account in accordance with the law, and that disease reaches the degree of essential treatment is very serious, say on the clinical meaning often to have missed the optimal treatment period and often be difficult to and cure or increase greatly treatment and cure difficulty, medical expense is also very high, many patients and family are difficult to bear, especially developing country is even more serious, the ratio that accounts for total population as China peasant is up to there not being medical care insurance more than 70% substantially, also has the expensive medical fee of same very important laid-off worker and indigent family's financial insolvency, let alone puted prevention first, even if also just can sell medicine as the U.S. because of the prescription drugs pharmacy that must the doctor prescribes in developed country and area, otherwise it is illegal, consumer then must pay expenses such as high prescription takes and surpass medicine valency itself outward, and nonprescription drugs, health food is that the dietotherapeutic product then need not prescription and expensive expense thereof, has alleviated consumer's financial burden greatly and made to buy to consume simple and direct and increase purchasing power, fulfill thereby making puts prevention first.Therefore unique legal effectively, economically feasible, to put prevention first, prevent and treat the scheme of taking into account just can only be screening, combination and design relevant new departure and new product in view of the above in legal dietotherapeutic medicine scope, because of such product could really accomplish good and cheap and meet the inveteracy consumption habit of consumer's " Diet cures more than the doctors ", consumer channel is unblocked, service group is extensive, its disease preventing and treating function and curative effect, safety and crowd's general applicability could also must gain public acceptance and serial relevant law such as state food health legislation is approved and protect.Total be exactly the present invention at prior art not enough, for one for solve an above-mentioned serial difficult problem the application of a kind of compositions in the medicine of preparation control soreness of the waist and knees that design of inventive concept, main Chinese medicine principle and function, advantage that its health that adopts officinal promulgated by the ministries or commissions of the Central Government is eaten dual-purpose raw material of Chinese medicine and the property of medicine and foundation are described below:
The sweet temperature of Fructus Lycii, add the smart marrow, the wind that makes eye bright, cloudy emerging sun mended and rise.Fructus Lycii sweet in the mouth, warm in nature has nourishing kidney to mend bone marrow, nourishing the liver to improve visual acuity and goes the wind effect, and it can yin nourishing, again can be supporing yang, so disease such as clinical impotence and seminal emission, the Yao Xi Acid that is usually used in insufficiency of kidney-YANG be soft also is used for the prosperous disease such as have a dizzy spell of deficiency of the kidney yin, liver-yang.
Rhizoma Dioscoreae (potato) Gan Wen, reason spleen antidiarrheal, kidney tonifying invigorating middle warmer, all void can be controlled.Potato sweet in the mouth, warm in nature has tonifying the spleen and stomach, stopping leak to rush down effect with nourishing kidney, is applicable to weakness of the spleen and stomach, inappetence, disease such as the chronic dysentery of having loose bowels and emission due to deficiency of the kidney, leukorrhagia, and controls and quench one's thirst, and all can treat the insufficient disease of weakness.
Fructus Chaenomelis sour in the mouth, damp-edema beriberi, the leaves of pulse plants be convulsion, the foot and knee being feeble disorderly.The Fructus Chaenomelis sour in the mouth, warm in nature, the effect of dehumidifying Shujin is arranged, kind control sufficient swelling and pain in knee or the numb vitamin B1 deficiency that damp causes, and the convulsion disease of the Calf muscle contraction urgency that can not nourishing muscle and tendon causes because of the consume of vomiting and diarrhoea body fluid, also have the effect of bone and muscle strengthening in addition, can control the foot and knee being feeble.Beriberi is a swelling of the feet pain, divides and does wet two kinds, and swollen person is a beriberi caused by pathogenic damp, pneumonedema but numb person is a dry beriberi.
Semen Euryales sweet in the mouth, the beneficial vital essence of energy, Yao Xi Acid pain, all main wet spleen.Semen Euryales sweet-puckery flavor, property are put down, and the effect of the kidney invigorating and essence nourishing is arranged, and can control the Yao Xi Acid pain of suffering from a deficiency of the kidney, and the energy removing dampness, so also effective to arthralgia chiefly caused by damp pathogen arthralgia.This product more has the effect of controlling nocturnal emission with astringent drugs and invigorating the spleen to arrest diarrhea, the seminal emission that can only suffer from a deficiency of the kidney and women's leucorrhea and insufficiency of the spleen chronic dysentery etc. of having loose bowels.This product is the Gorgon fruit.
The Semen Coicis sweet in the mouth, specially remove arthralgia chiefly caused by damp pathogen, muscles and joints-vital links in a speech contracture, lung abscess consumptive lung disease.Semen Coicis slightly sweet flavor, cold nature have the effect of the dehumidifying of strengthening the spleen and tonifying the lung, diuretic, clearing away heat and discharging pus, remove specially rheumatic arthralgia, joint contracture and water-damp retention edema, have loose bowels, oliguria, and control the lung carbunculosis of cough chest pain vomiting bloody pus and cough the consumptive lung disease of telling turbid sputum foam.
Hot, the kind promoting blood circulation of Cortex Cinnamomi, stomachache deficiency and coldness, temperature compensation can get.Cortex Cinnamomi acrid-sweet flavor, extremely hot in nature have the effect of YANG invigorating dispersing cold for relieving pain, are good at warm promoting blood circulation, are applicable to insufficiency of kidney-YANG, aversion to cold and cold limbs, chills and pain of the waist and kness, women's cold in blood amenorrhea, and diseases such as the coldness and pain in the epigastrium of deficiency and coldness, cold diarrhea, all can play the effect of temperature compensation.
Milk powder sweet in the mouth saltiness is flat, nourishing YIN Yiyang, please that face makes eye bright, vigorate qi and replenish the blood, controls the red and swollen puckery pain of binocular, makes eye bright, and curative effect is very good, and what can also promote important antioxidant glutathione synthesizes, is beneficial to the ability of improving body opposing aging and disease.Glutathion be one natural in the destructive antioxidant of opposing free radical, help the liver protecting to avoid the infringement of poisonous substance and some drugs.Yet directly take glutathion is not a wise move because its to belong to peptide class be the protein amino acid substance, most ofly during through digestive tract can seldom can be entered blood by gastric acid and digestive tract proteolytic enzyme digest.Therefore pharmacy seldom has the glutathion tonic to sell, but as taking the effect that the tonic that can make body produce more glutathion then can reach the compensation glutathion equally and remove free radical.Therefore the method for best raising body glutathion inside level is to take in the raw material of enough synthesizing glutathions, taking lactalbumin is to increase the synthetic effective ways of body glutathion inside: scientist has compared the influence to glutathion inside of 20 gram lactalbumins, placebo and 20 gram caseins in 20 health volunteers, found that lactalbumin can make glutathione level rising 20% in the blood, shows and can improve antioxidant status.One of them explanation is because contain a kind of sulfur-containing amino acid---cysteine in the milk surum, replenishes the glutathione level that nitrogen acetylcysteine (NAC) can improve human body.But the nitrogen acetylcysteine of long-term overdose might bring side effect, shows that because of experiment is arranged exacting practice (producing a large amount of free radicals) back takes the nitrogen acetylcysteine in conjunction with vitamin C and can make on the contrary that the interior free yl level raises, and the remarkable infringement degree of increase muscle! So the effect about it is also not too clear and definite.Do not recommend to be used for improving glutathione level.Therefore, lactalbumin is taken in recommendation rather than the nitrogen acetylcysteine stimulates body glutathion inside level, and that milk powder contains abundant lactalbumin, other nutrient substance is also very abundant, is undoubtedly superior choosing, adopts one of milk powder major reason so this also is the present invention.
Semen Pruni acid, dispelling the stagnated QI are moisturized, subsided a swelling convenient, obstruction and rejection admittance.Semen Pruni acrid in the mouth picric acid, property are put down, and the laxation of moisturizing, inducing diuresis to remove edema effect are arranged, and the energy removing blood stasis, can control the obstructed and diseases such as dysuria, edema distension of constipation due to dry stool, can make the joint tonneau.
Poria is lightly seasoned, the sharp key of eliminating dampness by diuresis, albefaction sputum, red waterway.Poria slightly sweet flavor, property are flat, sweet light can promoting diuresis to eliminate damp pathogen, so its effect is to make to rest on intravital water and drain from urethra, can control that the expectorant water stagnation is not changed and disease such as urinary obstruction.This product has red, white two kinds, the water that reduces phlegm is used Poria, diuresis always and is then used Poria.In addition, this product also is usually used in edema (use the skin) distension that causes because of water is wet and has loose bowels etc.
Fructus Rubi is sweet, kidney decreases that essence exhausts, blackly must make eye bright, tonify deficiency is continuous exhausted.The acid of Fructus Rubi sweet in the mouth, property are flat, the liver and the kidney tonifying controlling nocturnal emission with astringent drugs, control suffer from a deficiency of the kidney smart close not solid seminal emission, spermatorrhea, black beard and hair, are the active drugs of the kidney invigorating void.
The hot temperature of Fructus Alpiniae Oxyphyllae, the QI invigorating of calming the nerves, incontinence of urine seminal emission, vomiting are all controlled.The Fructus Alpiniae Oxyphyllae acrid in the mouth is warm in nature, and tranquilizing mind, the kidney invigorating gas are controlled the enuresis or the frequent micturition and the seminal emission of kidney qi deficiency and coldness, again can warming the spleen, control the nausea and vomiting disease of spleen-cold syndrome.
Sweet flat, the cough-relieving pus and blood of Colla Corii Asini, haematemesis tire collapse, empty win can be obeyed.The Colla Corii Asini sweet in the mouth is flat, enriches blood, hemostasis, nourishing YIN and moistening the lung, control cough due to consumptive disease, haematemesis, spit blood, have blood in stool and woman uterine bleeding or pregnant woman uterus hemorrhage etc., the dysphoria with smothery sensation in the heart that the deficiency of YIN also can be taken, also be controlled to body void disease such as must not sleep peacefully.Molten is used as medicine and is taken, goes into soup and fry in shallow oil and must fry use.
The Rhizoma Polygonati sweet in the mouth, can pacify internal organs, five kinds of strain and seven kinds of impairment, the big benefit of this medicine.Rhizoma Polygonati sweet in the mouth, property are flat, the spleen reinforcing lung moistening, and it is sick as weakness of the spleen and stomach, cough due to deficiency of the lung and disease such as quench one's thirst to control the deficient impairment caused by overstrain of internal organs.Five kinds of strain and seven kinds of impairment: hepatic asthenia, the impairment of the heart caused by overstrain, the impairment of the spleen due to overstrain, impairment of the kidney caused by overstrain; The big full impairment of the spleen, rage QI rising in reverse order impairing the liver, powerful weight lifting sitting wetland are impairment of the kidney, cold physique drink cold injury lung, sorrow are pondered over sad, wind and rain abnormal weather changes being apt to injure configuration of the body, big fear does not save the impairment of mentality.
Product of the present invention is by legal dietotherapeutic Chinese medicine Fructus Lycii 2-4 part, Rhizoma Dioscoreae 3-6 part, Fructus Chaenomelis 1.5-3 part, Semen Euryales 2-3 part, Semen Coicis 3-6 part, Cortex Cinnamomi 0-1 part, Semen Pruni 0-3 part, Poria 0-4 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part, Colla Corii Asini 2-4 part, Rhizoma Polygonati 3-5 part and milk powder are formed for raw material in right amount.
The manufacture method of product of the present invention is as follows:
A. decoction pieces type Chinese crude drug Fructus Lycii 2-4 part, Rhizoma Dioscoreae 3-6 part, Fructus Chaenomelis 1.5-3 part, Semen Euryales 2-3 part, Semen Coicis 3-6 part, Cortex Cinnamomi 0-1 part, Semen Pruni 0-3 part are on the waiting list in the choosing of raw material Chinese medicine, Poria 0-4 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part, Colla Corii Asini 2-4 part, Rhizoma Polygonati 3-5 part joins in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage (solubilized many be insoluble in the material of water and significantly improve drug effect) and adds the dilution of room temperature drinking water that to make ethanol (dense) degree be that alcohol content is the organic mixed solvent (mixed solution for extraction object Chinese medicinal ingredients material different liquids still can be considered solvent) with inorganic two kinds of solvent compositions of the sterilization type of 55-75% (V/V is a volume ratio), and alcoholic strength is lower than 55% or be higher than 75% equal difficulty and reach optimum extraction and sterilization effect;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of ethanol boiling point (to reduce evaporation of water and distillation as far as possible) vaporization ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, ensure that extracting solution utmost point low organic solvent is the high-quality of alcohol content, used cooling water extracts water as preheating, these measure and ensures the low energy consumption of production and product, low water consumption, low-cost, and avoided the pollution of organic solvent to environment and product, the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container room temperature (because of contain the few breeding of bacterium limited guarantee not putrid and deteriorated) soaked Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded to add (height) warm extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, add simultaneously (height) temperature (so the time contain bacterium may be than d for high) lower the temperature slowly naturally after 3-5 minute to boiling that (summer high temperature was lowered the temperature and can suitably be aided with the room temperature water-cooled too slowly in about 20-30 minute, the same recyclable described preheating water of c of incorporating into of cooling water) continues stripping and energy-saving and water-saving to 60-70 ℃ in order to pharmaceutical compositions, extract and must high temperature could propose and low temperature is not carried most material composition, and make and heat rapidly and evenly, reduce material damage and loss, with further raising drug effect and recovery rate, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, the medicinal residues that discard behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed are the acyclic dirts of agricultural soil high-quality fertilizer of returning crop stocks to the field, and medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product of the present invention is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, add Chinese medicine extraction liquid, be the solution dry matter content that concentration promotes and is 35-40% by milk powder 3-5 part and lactose 1-3 part part by weight, be spray dried into water content and get product below 3%, host or additive as food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP; Compacting (lactose and all very easily compression moulding of milk powder) becomes Any shape such as the sheet, grain, ball of 0.2-0.4 gram, as food, nutriment, health product and medicine, advises oral every day 2-3 time, 0.4-0.8 restrains at every turn, need not the branch of crowd and dosage.
The purposes of product of the present invention, usage and consumption: as food, nutriment, health product and medicine, oral every day 2-3 time, each 0.4-0.8 restrain, and need not the branch of crowd and dosage; As the host or the additive of food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP.
Embodiment:
1, drinks 2 parts of sheet type Chinese crude drug Fructus Lyciis, 3 parts of Rhizoma Dioscoreaes, 1.5 parts of Fructus Chaenomeliss, 2 parts of Semen Euryaless, 3 parts of Semen Coiciss, 1.5 parts of Fructus Rubies, 1 part of Fructus Alpiniae Oxyphyllae, 2 parts in Colla Corii Asini, 3 parts of Rhizoma Polygonatis, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the daily life health food that puts prevention first.
2, drink 2 parts of sheet type Chinese crude drug Fructus Lyciis, 3 parts of Rhizoma Dioscoreaes, 1.5 parts of Fructus Chaenomeliss, 2 parts of Semen Euryaless, 3 parts of Semen Coiciss, 0.5 part of Cortex Cinnamomi, 1 part of Semen Pruni, 1 part in Poria, 1.5 parts of Fructus Rubies, 1 part of Fructus Alpiniae Oxyphyllae, 2 parts in Colla Corii Asini, 3 parts of Rhizoma Polygonatis are made compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and are got raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the light patient of the their early stage or the state of an illness.
3, drink 4 parts of sheet type Chinese crude drug Fructus Lyciis, 6 parts of Rhizoma Dioscoreaes, 3 parts of Fructus Chaenomeliss, 3 parts of Semen Euryaless, 6 parts of Semen Coiciss, 1 part of Cortex Cinnamomi, 3 parts of Semen Prunis, 4 parts in Poria, 3 parts of Fructus Rubies, 3 parts of Fructus Alpiniae Oxyphyllaes, 4 parts in Colla Corii Asini, 5 parts of Rhizoma Polygonatis are made compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and are got raw produce, and the Any shape such as sheet, grain, ball that product of the present invention are pressed into 0.2-0.4 gram get product.Be mainly used in the long or heavier patient of the state of an illness of the course of disease.
Supplementary copy inventive principle and advantage are as follows:
1, the present invention adopts the low lactose of water absorption to do complexion changed and easy preservation that filler can reduce duration of storage, so storage life is that the commodity shelf life is long, economic worth is high; And form most crowds jointly with the acescency of little sweet taste of lactose and Fructus Lycii, Fructus Chaenomelis, Herba Portulacae and like the popular taste products of " little sweet little acid " of eating and easily be accepted, so service face and service group are the most extensive, its society and economic benefit are also just apparent naturally.
2; the property of medicine of Chinese prescription medical material is with flat; cool; it is main and cold with the torrid zone being slightly cold; with temperature; flat rubber belting is slightly cold etc.; also take into account simultaneously and liver (gallbladder); relevant other organ of order after one's own heart; lung; spleen; the protection of the function of kidney and coordination; Chinese medicine organic conception and advantage have been demonstrated fully; make drug effect and function more comprehensive and mark; this double controlling; realized that Chinese medicine property of medicine general inclination is in gentle and promote the high boundary of drug effect mutually; especially can regulate application simultaneously with the medicine of Yin Yang balancing strength; thereby make the moon; sun balance of force and mutual regulating power all can reach balance and gentle; all kinds of diseases and ailments are spontaneous recovery; and because of the legal dietotherapeutic of all medical materials; effect certainly and do not have a toxic and side effects; be suitable for any crowd and serve wide, this just the present invention to the imbody of the wide main advantages of Chinese medicine adaptive surface.
3, medicine variety and function all are legal medicine-food two-purposes and simple and clear and do not have a dispute, and the multiple state of an illness of prescription adaptation versatile and flexible and select medication properer has been opened up out Chinese medicine and debated disease and execute tool body content and range of application.
4, all medical materials all are conventional varieties and do not have hormone and toxic and side effects, so quality, the source is secure and aboundresources is cheap, product of the present invention can be consumed by vast general patient because of no patient crowd's branch event and obtain and afford to consume, and the realization new and high technology is served lofty aim for the most numerous common people.
5, innovate organic and inorganic mixed solvent and extract at room temperature and reclaim organic solvent and recycle molten and water-soluble substances and energy-conservation joint (cooling) water of Extraction oil with being beneficial to synchronously high-quality and high recovery rate, again with inorganic solvent and room temperature and high temperature combined extractive technique, scheme and technology, ensured extraction overall process asepticize, can carry substantially many to the greatest extent be insoluble in water or be insoluble in oil material and significantly improve drug effect and extract quality and content, and extraction ratio height, with short production cycle, energy-saving and water-saving, product cost is low, do not have (organic solvent) and pollute, its serial comprehensive advantage is traditional decocting and single with organic solvent or water or some other is because of expensive, highly difficult, the product of receiving single (fact proved and the generally acknowledged both at home and abroad compound composition extract of Chinese medicine than single composition extract good effect, this was exactly the essence and the inherent feature place of Chinese medicine originally and was determined by it), recovery rate low and short-term even long duration are difficult to that so-called modern Chinese medicine extractive technique that penetration and promotion uses is difficult to mention in the same breath.
6, become the favorable factor of the defective of China and Asia average 80% above population Lactose enzyme indigestibility absorption for want of (as milk) lactose into disease preventing and treating, because adopt lactose to replace the starch of easily digesting and assimilating and dextrin is made adsorbent and filler can significantly slow down the medicine slow release speed and avoid taking a very Peter Pans historic difficult problem beyond affordability of traditional decocting Chinese medicine amount, thereby significantly prolong the efficacy of a drug persistent period and improve curative effect and possible medicine irritation is relieved to bottom line.
More than these also are the great novelty and the practicality of the legal approval of Patent Law.
Test method, data and presentation of results and prompting:
Disease that product of the present invention is controlled belongs to common frdquently encountered disease so tool is extensively representative, experimenter's voluntary participation.Product of the present invention because of good effect and have no side effect and crowd's branch, so treatment cycle is short and cure rate is high, make test be easy to just satisfactorily be finished, now further be explained as follows (only for reference) with allow keeping in Patent Law about situation under the prerequisite of necessary KNOW-HOW and business secret and please understand: it is 2 groups that totally 40 of the test patients at different sexes, age, 20 people are divided into for one group: one group with product of the present invention and usage and dosage prevent and treat, one group of not medication compares; Test number and time on test reach the equal tool statistical significance of 2 first quarter moons, test number and experimental period so suitable representativeness and credibility are arranged.The result is as follows: none the routine state of an illness of test group personnel with product of the present invention is deepened, and 5 people's no changes are arranged, and has 15 people to improve; The state of an illness is than the lighter's promptly be significantly improved after one week, not only can stand up rapidly behind the especially dizzy person 2-3 days unlikely astasia and substantially unconsciously pupil is or/and have a dizzy spell, and this also belongs to more rare instant effect, eutherapeutic example in the chronic disease treatment by Chinese herbs; The matched group experimenter finds the state of an illness person of increasing the weight of 16 people, and 4 people feel no significant change, none state of an illness improver.Prompting: the state of an illness does not deepen just to prove absolutely that the state of an illness is controlled, is that product of the present invention is effective that the direction that the state of an illness improvement explanation state of an illness is become better reverses, is that product efficacy of the present invention is remarkable.
To sum up state, raw material of the present invention, product and method belong to a total inventive concept, economic environmental protection good effect, be suitable for the crowd and market is all very wide, helpfulness and the degree of association are also very high.

Claims (1)

1. the compositions application in the medicine of preparation control soreness of the waist and knees is characterized in that said composition makes by following step:
A. drink sheet type Chinese crude drug Fructus Lycii 2-4 part, Rhizoma Dioscoreae 3-6 part, Fructus Chaenomelis 1.5-3 part, Semen Euryales 2-3 part, Semen Coicis 3-6 part, Cortex Cinnamomi 0-1 part, Semen Pruni 0-3 part, Poria 0-4 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part, Colla Corii Asini 2-4 part, Rhizoma Polygonati 3-5 part joins in the nonmetallic surface container of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage and adds the dilution of room temperature drinking water that to make alcoholic strength be that alcohol content is the organic and inorganic mixed solvent of 55-75%V/V;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, heater accurately is heated to 78-80 ℃ of vaporization of ethanol boiling point ethanol respectively with medicinal residues and medicinal liquid, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, used cooling water extracts water as preheating, and the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container soak at room temperature Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. water is proceeded to heat to extract to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, being warmed to boiling simultaneously slowly lowered the temperature about 20-30 minute to 60-70 ℃ after 3-5 minute naturally, the summer high temperature cooling suitably is aided with the room temperature water-cooled too slowly, the same recyclable described preheating water of c of incorporating into of cooling water, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, discard medicinal residues behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, add Chinese medicine extraction liquid, be the solution dry matter content that concentration promotes and is 35-40% by milk powder 3-5 part and lactose 1-3 part part by weight, be spray dried into water content below 3% promptly.
CNB2005101364364A 2005-12-29 2005-12-29 Medicine and food dual purpose Chinese medicinal nutritive product for preventing and treating limp lumbus and knees and its manufacturing method Expired - Fee Related CN100394974C (en)

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CN100393348C (en) * 2005-12-29 2008-06-11 颜怀伟 Medicine and food dual purpose Chinese medicinal product for preventing and treating weak lumbus and legs and its manufacturing method
CN100394975C (en) * 2005-12-29 2008-06-18 颜怀伟 Medicine and food dual purpose Chinese medicinal product for preventing and treating painful swollen legs and feat and its manufacturing method
CN109511981A (en) * 2018-12-18 2019-03-26 湖南橘色科技有限责任公司 A kind of strengthening the muscles and bones composition and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1238197A (en) * 1998-05-15 1999-12-15 陈春森 Chinese-medicinal capsule (Shenyihuichun Dan) for treating male sexual disfunction
CN1824222A (en) * 2005-12-29 2006-08-30 颜怀伟 Medicine and food dual purpose Chinese medicinal product for preventing and treating painful swollen legs and feat and its manufacturing method
CN1824223A (en) * 2005-12-29 2006-08-30 颜怀伟 Medicine and food dual purpose Chinese medicinal product for preventing and treating weak lumbus and legs and its manufacturing method

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1238197A (en) * 1998-05-15 1999-12-15 陈春森 Chinese-medicinal capsule (Shenyihuichun Dan) for treating male sexual disfunction
CN1824222A (en) * 2005-12-29 2006-08-30 颜怀伟 Medicine and food dual purpose Chinese medicinal product for preventing and treating painful swollen legs and feat and its manufacturing method
CN1824223A (en) * 2005-12-29 2006-08-30 颜怀伟 Medicine and food dual purpose Chinese medicinal product for preventing and treating weak lumbus and legs and its manufacturing method

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