CN1695675A - Chinese traditional medicine for treating diarrhea of infant and preparation method - Google Patents

Abstract

A Chinese medicine for treating infantile diarrhea is prepared from 19 Chinese-medicinal materials including yam, plantain seed, etc. Its preparing process is also disclosed.

Description

Chinese medicine of treatment infantile diarrhea and preparation method thereof

Affiliated field: the present invention relates to a kind of Chinese medicine for the treatment of infantile diarrhea and preparation method thereof.

Background technology: infantile diarrhea is all generable commonly encountered diseases throughout the year.To see autumn and winter,, influence the healthy and growth of infant as untimely reverse more.Chinese medicine is thought: children's's internal organs are tender and lovely, and shape gas does not fill, and digestive function of spleen and stomach is low, are the body of the young sun of young the moon, and cold and heat can not self-regulated in addition, and diet is not known from joint, very easily diseases caused by exogenous pathogenic factor seasonal pathogen.Cause transporting and transforming function of the spleen and stomach not normal and bring out primary disease.As " A complete work on Pediatrics, a collection and arrangement of the chief contents from ancient pediatrics, written by Chen Fuzheng " cloud: " have loose bowels this, invariably because taste are impaired, then instead for wet, Gu Fanwei's water stagnates, dysfunction of the spleen in transportation and transformation." because the physiological characteristics of infant the spleen tending to insufficiency usually, weakness of the spleen and stomach, or body void after being ill, transporting and transforming function of the spleen and stomach is not normal; Or improper feeding, diseases caused by exogenous pathogenic factor wind, cold, summer-heat, wet heresy more makes taste sleepy, and digestion breast food, digesting food function are weak, cause water paddy and are regardless of, and walk large intestine and form and have loose bowels.Infantile diarrhea was fallen ill at most with interior children's with 1 years old, and not sound as yet with this age digestive system function, digestive enzyme lacks or reduces, thereby poor to the tolerance of breast food.Be children's's the spleen tending to insufficiency usually, its fortune is not entirely in the concentrated reflection of primary disease.Spleen is the dirty of wet soil, and it is wet to like dry evil, gets positive beginning fortune, and meeting wets then is stranded.Damp is the virulence factor and the pathological product of primary disease.The spleen tending to insufficiency usually then makes spleen soil be subject to kill wound, and causing the wet meat of spleen to steep is the delay sexually transmitted disease (STD) reason characteristics and the basic pattern of syndrome of primary disease.Modern medicine thinks that the main pathogeny of children's's diarrheal autumn and winter is rotavirus infection.Children's's immunologic function is low, and virus is invaded the Epithelium of intestinal villus cell, causes crypts and gland nest cell dysfunction, causes secretion and the disorder of Water-Electrolyte absorption function, causes infectious diarrhea.This type of diarrhoea uses antibiotic invalid.Bacterial infection (comprises rotten property breast food diarrhoea in addition, if use antibiotic improper, antibiotic is widely applied for a long time in addition, cause pathogenic bacteria to develop immunity to drugs in various degree, also be difficult to receive desired therapeutic effect, if long-term a large amount of antibiotic that uses, not only directly stimulate intestinal or vegetative nerve, cause the quickening of intestinal smooth muscle wriggling, glucose absorption is reduced, disaccharidase is active to be reduced, and suffer from diarrhoea, even can suppress non-pathogenic bacteria in the intestines and stomach, cause the gastrointestinal bacterial flora imbalance and suffer from diarrhoea, or make difficult the healing of original diarrhoea delay.Also some infantile diarrhea does not have tangible calendar variation and infectious feature, eats breast milk or dairy products (as milk, milk powder etc.) after the birth and promptly suffers from diarrhoea.Such diarrhoea is most to be that the infant lactose intolerance is suffered from diarrhoea.Its pathogeny is children's's intestinal mucosa lactase deficiency, can not catapepsis, decompose breast milk or lactose in milk, and cause the normal intestinal microbial population of lactose in enteric cavity to resolve into lactic acid, carbon dioxide and water, abdominal distention appears, stomachache, diarrhoea.Its clinical characters is promptly rushed down after eating.Some infantile diarrhea does not have the clear and definite cause of disease of bringing out in addition, and lab testing does not have positive the discovery more.This type of diarrhoea is called lienteric diarrhea.It is not perfect because of the growth of the spleen and stomach in children digestive function, and weakness of the spleen and stomach is not normal as diet, makes taste impaired, and digestive function weakness, malabsorption cause diarrhoea.Children's's body is real, and QI and blood is not filled, and easily empty easily real a little less than manner is dispelled, the rapid scaring of meeting makes the liver and gall mechanism of qi disorderly contrary, perverse and unreasonable manner taste, dysfunction of the spleen in transportation and suffering from diarrhoea.Be diarrhea induced by fright.The kidney being the origin of congenital constitution, and spleen is the day after tomorrow, and children's's body is unreal, and kidney qi is not filled.Waist is a house of kidney, because nurture is improper, turns round the body of spraining one's back, and kidney qi is impaired, unablely takes the day after tomorrow into account.The kidney qi wound is regulating fluid apssage normally, causes the defeated water distribution liquid functional disorder of spleen and causes diarrhoea.Wang Ang once said: " chronic diarrhea is all declined for a long time by the gate of vitality, can not specialize in taste." have cold, cool, summer-heat, wet contamination or drug use improper again, tried out gram cuts down taste, all can cause diarrhoea.This shows that infantile diarrhea can be by multi-pathogenesis, multifactor causing.As untimely reverse, but delay with the passing of time secondary water, electrolyte disturbance and acid base imbalance, cause chronic diarrhea or intractable diarrhoea, malnutrition and serious symptoms such as growth retardation, stagnation occur.Recent two decades causes domestic doctor scholar's attention gradually, but is devoted to the research of epidemiology, hereditism and clinical diagnosis aspect more, and the report of relevant treatment is few.At the multi-pathogenesis of infantile diarrhea, multifactor morbific complexity, also do not have a kind of medicine system clinically and control it.Children's's " gas is weak for its fragile muscle, insufficiency of blood " physiological characteristics in addition, difficult evil of appointing bias of medicine when treatment, its medication is stayed slightly then and is stagnated, and heavyly slightly then hinders.

Summary of the invention: the purpose of this invention is to provide a kind of curative effect certainly.And short treating period, cheap, the property of medicine is gentle, Chinese medicine of no side effects, safe and reliable treatment infantile diarrhea and preparation method thereof.The objective of the invention is to realize by following technology bill: the present invention is a kind of Chinese medicine for the treatment of infantile diarrhea, and the weight proportion of this drug component is: Rhizoma Dioscoreae 50--100g, Poria 50--100g, Semen Plantaginis 50--100g, Rhizoma Atractylodis Macrocephalae 40--65g, Semen Myristicae 40--65g, Rhizoma Atractylodis 40--65g, Semen Euryales 40--65g, Radix Ginseng 30--55g, Cortex Cinnamomi 30--55g, Radix Aucklandiae 30--55g, Seem Lablab Album 20-35g, Galla Chinensis 20-35g, Fructus Chebulae 20-35g, Fructus Amomi 30--40g, Flos Caryophylli 30--40g, Fructus Mume 30--40g, Catechu 30--50g, Radix Glycyrrhizae 10--20g, Scolopendra 9--15g.The preparation method of described this medicine is: A: get the raw materials ready: Semen Plantaginis is fried to half-done, Fructus Chebulae, Semen Myristicae: face is wrapped up in, charcoal fire is simmered and deoiled, with medicine invariant color degree of being, and Fructus Mume: enucleation, Scolopendra: decaptitate, foot; The low baking temperature roasting is yellow; B: above raw material and Rhizoma Dioscoreae, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Semen Euryales, Radix Ginseng, Cortex Cinnamomi, the Radix Aucklandiae, Seem Lablab Album, Galla Chinensis, Fructus Amomi, Flos Caryophylli, Catechu, Radix Glycyrrhizae, get clean amount, be ground into powder; C: be placed in the pressure vessel and pressurize, pressure is 2.0Kpa, temperature 140 degree Celsius, and 20 minutes, take out natural drying and be finished product, encapsulate standby.The present invention catches taste impaired according to the wet theory of the traditional Chinese medical science The spleen has the function to transport and transform nutrients water, the key of damp for suffering from.In the medication, prescription of treatment infantile diarrhea, must catch this emphasis of function of spleen and stomach regulating, invigorating the spleen for eliminating dampness, heat clearing away cold expelling, supplementing QI for promoting the production of body fluid, warming YANG and in, suppressing the hyperactive liver kidney tonifying, spasmolytic astringing intestine to stop diarrhea, take off antidiarrheal admittedly.Radix Ginseng tonifying QI to produce body fluid, wet and oiliness, tonify without causing stagnation among the present invention.Poria, Semen Plantaginis invigorating spleen to remove dampness, Rhizoma Dioscoreae spleen reinforcing lung kidney, QI invigorating is established the yang function, and is used for anorexia and loose stool.The chronic dysentery of having loose bowels; The Seem Lablab Album invigorating the spleen for eliminating dampness, clearing away summer-heat heat, emesis rushes down, Semen Myristicae warming middle-JIAO to promote flow of QI, relieving diarrhea with astringents; All kinds of diarrhoea all there is good effect.Rhizoma Atractylodis fragrance dampness, be amusing and help fortune, " spleen mending, is not valued for fortune." being just accord with the habit of spleen, activating the spleen is with the lucid yang sending up, and damp eliminating is to activate yang.The Radix Aucklandiae, Fructus Amomi spleen invigorating circulation of qi promoting; Fructus Mume, Galla Chinensis, the Fructus Chebulae astringing intestine to stop diarrhea of astringing the lung, the antidiarrheal of promoting the production of body fluid; It is supporing yang that Cortex Cinnamomi is mended fire; Wet main cloudy, get positive then change.Flos Caryophylli warming the kidney to activate YANG stopping nausea and vomiting by lowering the adverse flow of QI; The Catechu strengthening the spleen and stomach, clearing away damp-heat, spleen reinforcing antidiarrheal.Rhizoma Atractylodis Macrocephalae replenishing QI to invigorate the spleen, the damp eliminating of Semen Euryales kidney tonifying, spleen reinforcing antidiarrheal.Because of soil loses the Herba Equiseti Hiemalis, often there is liver-wind to sprout, Scolopendra relieving spasm by subduing liver-wind, detoxifcation, all medicines of Radix Glycyrrhizae detoxifcation blending are to separate the poison of Scolopendra.Through modern pharmacological research: Poria contains protein, fat, sterol, glucose, histidine, the poly-sour catabolic enzyme of B---, multiple nutrients material and ingredients such as protease.Also have mind tranquilizing and the heart calming, remove agitation, enhancing immunity and antibacterial action through clinical verification.Looking at it from this point of view, Poria is the ideal medicament of treatment infantile diarrhea.Cortex Cinnamomi is removed the visceral smooth muscle spasm; Alleviate the intestinal spasmic pain.Flos Caryophylli has the obvious suppression effect to escherichia coli, dysentery bacterium; Strengthen digestion power.Fructus Mume, Galla Chinensis all have tangible bacteriostasis and sterilization effect.Scolopendra spasmolytic, antibiotic, antiviral improve immunity.Catechu has antibacterial, antivirus action.The Fructus Chebulae all has antibacterial action to various dysentery bacteriums, escherichia coli etc.; The Radix Glycyrrhizae antivirus action.

Zhang Xichun says: " Rhizoma Dioscoreae defecates admittedly, diuresis; Semen Plantaginis diuresis and YIN nourishing is share capable enriching yin and nourishing kidney, the merit that treats diarrhea with diuretics." two medicines mutually 5, to control stagnation of dampness due to deficiency of the spleen and have loose bowels, diuretic is wet, deposits Kidney-Yinly, and hold concurrently anti-dampness removing and just hinder, Radix Ginseng, close Rhizoma Atractylodis Macrocephalae replenishing QI to invigorate the spleen, Poria, Flos Caryophylli, Fructus Amomi, the Cortex Cinnamomi warming middle-JIAO of calming the nerves, invigorating the spleen to arrest diarrhea, Deficiency and coldness of spleen and stomach rushed down special effect.Scolopendra, Cortex Cinnamomi, Flos Caryophylli are declared the gas that activates yang, and search by the blood network, improve intestinal mucosa blood fortune, recover the intestinal mucosa function.Rhizoma Dioscoreae, Semen Euryales, Semen Plantaginis tonifying speen and tonifying kidney dampness removing.Radix Aucklandiae regulating QI warming middle-JIAO to stop diarrhea removes the preventing or arresting vomiting that expands; Scolopendra, Radix Glycyrrhizae, Catechu detoxifcation, antibacterial, antiviral, good to children's antibacterial, alimentary toxicosis diarrhoea curative effect.All medicines share, invigorating the spleen for eliminating dampness, the heat clearing away cold expelling, warming YANG and in, suppressing the hyperactive liver kidney tonifying, supplementing QI to prevent collapse, relieving diarrhea with astringents.The process of preparing Chinese medicine of medicine heightens the effect of a treatment, and subtracts the toxic and side effects and the high strong property of falling or eliminating medicine.

The present invention verifies that through clinical observation the curative effect of powder is excellent than decoction.Powder is loosing in the intestinal, intestines and stomach is produced directly effect, and the time of staying is longer, more helps drug absorption, the utilization rate of raising medicine.By clinical comparison, the consumption of powder is about the 1/15------1/20 of decoction.Dosage is few, avoids infant is produced the fraud of poisoning.And feeding is convenient.

By clinical observation checking in surplus ten years, said preparation was treated various infantile diarrhea and be need not dialectically, and curative effect is sure.And short treating period, cheap, the property of medicine is gentle, no side effects.Medicine is purified without other technology, keeps original property of medicine.Every herbal medicine consumption is easy to grasp.Need not to carry out the clinical pharmacology toxicity test.Safe and reliable.According to the traditional Chinese medical science theory that The spleen has the function to transport and transform nutrients, catch taste impaired, the key of damp for suffering from.In the medication, prescription of treatment infantile diarrhea, must catch this emphasis of function of spleen and stomach regulating, invigorating the spleen for eliminating dampness, heat clearing away cold expelling, supplementing QI for promoting the production of body fluid, warming YANG and in, suppressing the hyperactive liver kidney tonifying, spasmolytic astringing intestine to stop diarrhea, take off antidiarrheal admittedly.

The specific embodiment:

The weight proportion of drug component of the present invention is: Rhizoma Dioscoreae 50--100g, Poria 50--100g, Semen Plantaginis 50--100g, Rhizoma Atractylodis Macrocephalae 40--65g, Semen Myristicae 40--65g, Rhizoma Atractylodis 40--65g, Semen Euryales 40--65g, Radix Ginseng 30--55g, Cortex Cinnamomi 30--55g, Radix Aucklandiae 30--55g, Seem Lablab Album 20-35g, Galla Chinensis 20--35g, Fructus Chebulae 20--35g, Fructus Amomi 30--40g, Flos Caryophylli 30--40g, Fructus Mume 30--40g, Catechu 30--50g, Radix Glycyrrhizae 10--20g, Scolopendra 9--15g.

Concrete weight proportion in the present embodiment is: Rhizoma Dioscoreae 60g, Poria 60g, Semen Plantaginis 60g, Rhizoma Atractylodis Macrocephalae 48g, Semen Myristicae 48g, Rhizoma Atractylodis 48g, Semen Euryales 48g, Radix Ginseng 40g, Cortex Cinnamomi 40g, Radix Aucklandiae 40g, Seem Lablab Album 24g, Galla Chinensis 24g, Fructus Chebulae 24g, Fructus Amomi 20g, Flos Caryophylli 20g, Fructus Mume 36g, Catechu 32g, Radix Glycyrrhizae 18g, Scolopendra 10g.

Preparation method of the present invention is:

A: get the raw materials ready: Semen Plantaginis is fried to half-done, Fructus Chebulae, Semen Myristicae: face is wrapped up in, charcoal fire is simmered and deoiled, with medicine invariant color degree of being, and Fructus Mume: enucleation, Scolopendra: decaptitate, foot; The low baking temperature roasting is yellow; B: above raw material and Rhizoma Dioscoreae, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Semen Euryales, Radix Ginseng, Cortex Cinnamomi, the Radix Aucklandiae, Seem Lablab Album, Galla Chinensis, Fructus Amomi, Flos Caryophylli, Catechu, Radix Glycyrrhizae, get clean amount, be ground into powder; C: be placed in the pressure vessel and pressurize, pressure is 2.0Kpa, temperature 140 degree Celsius, and 20 minutes, take out natural drying and be finished product, encapsulate standby.Technique effect of the present invention provides imbody by table 1.

--2 one full year of life 3.0--3.5g2 one full year of life of 6 months 1.5--2g 7 months-1 one full year of life 2.0--2.5g1 one full year of life--1.5 one full year of life of 1.5 one full year of life 2.5--3.0g--, above the meal with wine added consumption: birth.More than be daily dose, divide 2 times oral.All case is not given venous transfusion, all cures in 1 one full year of life.

Treatment infantile diarrhea Chinese medicine preparation curative effect index chart

The cause of disease distributes	The example number	Age	Wherein		Cure	Effectively	Invalid	Remarks
									The man	The woman
			Rotavirus	142							21 days-3 one full year of life	65	77	140	1	1
Lactose intolerance	58	4 days-4 first quarter moons			27	31	56	2
			Dyspepsia	131							7 days-3 one full year of life	60	71	124	7
Scaring property	45	9 days-21 months			19	26	45
			Being impairment of the kidney property	32							20 days-18 months	18	14	32
The unclean property of food	50 ?	18 days-3.5 one full year of life			18 ?	32 ?	47 ?	2 ?	1 ?
			Medicine	31							4 days-4 one full year of life	16	15	29	1	1
Agnogenio	6	2 months-15 months			2	4	4	1	1
			Add up to	495								276	269	277	14	4

The component of this medicine is: Rhizoma Dioscoreae, Poria, Semen Plantaginis, the Rhizoma Atractylodis Macrocephalae, Semen Myristicae, Rhizoma Atractylodis, Semen Euryales, Radix Ginseng, Cortex Cinnamomi, the Radix Aucklandiae, Seem Lablab Album, Galla Chinensis, Fructus Chebulae, Fructus Amomi, Flos Caryophylli, Fructus Mume, Catechu, Radix Glycyrrhizae, Scolopendra.

Claims (2)

1, a kind of Chinese medicine for the treatment of infantile diarrhea, it is characterized in that: the weight proportion of this drug component is: Rhizoma Dioscoreae 50--100g, Poria 50--100g, Semen Plantaginis 50--100g, Rhizoma Atractylodis Macrocephalae 40--65g, Semen Myristicae 40--65g, Rhizoma Atractylodis 40--65g, Semen Euryales 40--65g, Radix Ginseng 30--55 g, Cortex Cinnamomi 30--55 g, Radix Aucklandiae 30--55 g, Seem Lablab Album 20--35g, Galla Chinensis 20--35g, Fructus Chebulae 20--35g, Fructus Amomi 30--40g, Flos Caryophylli 30--40g, Fructus Mume 30--40g, Catechu 30--50g, Radix Glycyrrhizae 10--20g, Scolopendra 9--15g.

2, a kind of its preparation method for the treatment of infantile diarrhea Chinese medicine according to claim 1, it is characterized in that: A: get the raw materials ready: Semen Plantaginis is fried to half-done, Fructus Chebulae, Semen Myristicae: face is wrapped up in, charcoal fire is simmered and deoiled, with medicine invariant color degree of being, Fructus Mume: enucleation, Scolopendra: decaptitate, the foot; The low baking temperature roasting is yellow; B: above raw material and Rhizoma Dioscoreae, Poria, the Rhizoma Atractylodis Macrocephalae, Rhizoma Atractylodis, Semen Euryales, Radix Ginseng, Cortex Cinnamomi, the Radix Aucklandiae, Seem Lablab Album, Galla Chinensis, Fructus Amomi, Flos Caryophylli, Catechu, Radix Glycyrrhizae, get clean amount, be ground into powder; C: be placed in the pressure vessel and pressurize, pressure is 2.0Kpa, temperature 140 degree Celsius, and 20 minutes, take out natural drying and be finished product, encapsulate standby.