CL2018000155A1 - Composiciones de adyuvante liposomal - Google Patents

Composiciones de adyuvante liposomal

Info

Publication number
CL2018000155A1
CL2018000155A1 CL2018000155A CL2018000155A CL2018000155A1 CL 2018000155 A1 CL2018000155 A1 CL 2018000155A1 CL 2018000155 A CL2018000155 A CL 2018000155A CL 2018000155 A CL2018000155 A CL 2018000155A CL 2018000155 A1 CL2018000155 A1 CL 2018000155A1
Authority
CL
Chile
Prior art keywords
liposomal
adjuvant compositions
liposomal adjuvant
assistant
external membrane
Prior art date
Application number
CL2018000155A
Other languages
English (en)
Inventor
Paul Joseph Dominowski
Duncan Mwangi
Sharath K Rai
Dennis L Foss
Traci K Godbee
Laurel Mary Sly
Suman Mahan
Shaunak Vora
Original Assignee
Zoetis Services Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zoetis Services Llc filed Critical Zoetis Services Llc
Publication of CL2018000155A1 publication Critical patent/CL2018000155A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1273—Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

<p>LA INVENCIÓN PROPORCIONA UNA COMPOSICIÓN DE ADYUVANTE LIPOSOMAL QUE COMPRENDE UNA MEMBRANA EXTERNA Y UN COMPARTIMIENTO INTERNO, LA MEMBRANA EXTERNA COMPRENDE: UN COMPUESTO DE AMONIO CUATERNARIO; UN ESTEROL; UN FOSFOLÍPIDO Y UN GLICOLÍPIDO. TAMBIÉN SE PROPORCIONAN COMPOSICIONES DE VACUNA QUE COMPRENDEN EL ADYUVANTE LIPOSOMAL DE LA PRESENTE INVENCIÓN.</p>
CL2018000155A 2015-07-20 2018-01-19 Composiciones de adyuvante liposomal CL2018000155A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562194355P 2015-07-20 2015-07-20

Publications (1)

Publication Number Publication Date
CL2018000155A1 true CL2018000155A1 (es) 2018-06-08

Family

ID=56555804

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2018000155A CL2018000155A1 (es) 2015-07-20 2018-01-19 Composiciones de adyuvante liposomal

Country Status (28)

Country Link
EP (1) EP3325015B1 (es)
JP (1) JP6975132B2 (es)
KR (1) KR102085968B1 (es)
CN (1) CN107847603B (es)
AR (1) AR105393A1 (es)
AU (1) AU2016297529B2 (es)
BR (1) BR112018001318B1 (es)
CA (1) CA2992892C (es)
CL (1) CL2018000155A1 (es)
CO (1) CO2018000496A2 (es)
CY (1) CY1124319T1 (es)
DK (1) DK3325015T3 (es)
ES (1) ES2878475T3 (es)
HK (1) HK1250338A1 (es)
HR (1) HRP20210872T1 (es)
HU (1) HUE054422T2 (es)
LT (1) LT3325015T (es)
MX (1) MX2018000879A (es)
PH (1) PH12018500146A1 (es)
PL (1) PL3325015T3 (es)
PT (1) PT3325015T (es)
RS (1) RS62015B1 (es)
RU (1) RU2736642C2 (es)
SI (1) SI3325015T1 (es)
TW (1) TWI655002B (es)
UA (1) UA125017C2 (es)
WO (1) WO2017015252A1 (es)
ZA (1) ZA201800285B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW202206098A (zh) * 2020-08-11 2022-02-16 美商碩騰服務公司 抗冠狀病毒疫苗

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3521994A1 (de) * 1985-06-20 1987-01-02 Bayer Ag N-(2-aminoacylamido-2-desoxy-hexosyl)-amide-, -carbamate und -harnstoffe, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
US5556637A (en) * 1990-08-06 1996-09-17 A. Nattermann & Cie. Gmbh Water containing liposome system
EP0979100A1 (fr) * 1997-04-30 2000-02-16 Merieux OraVax SNC COMPOSITION VACCINALE ANTI-$i(HELICOBACTER) COMPRENANT UN ADJUVANT DE TYPE TH1
US8088388B2 (en) * 2002-02-14 2012-01-03 United Biomedical, Inc. Stabilized synthetic immunogen delivery system
EP1547581A1 (en) * 2003-12-23 2005-06-29 Vectron Therapeutics AG Liposomal vaccine for the treatment of human hematological malignancies
US7749520B2 (en) * 2004-07-07 2010-07-06 Statens Serum Institut Compositions and methods for stabilizing lipid based adjuvant formulations using glycolipids
PT1765289E (pt) * 2004-07-07 2008-12-05 Statens Seruminstitut Composições e processos para estabilizar formulações de adjuvantes à base de lípidos por meio de glicolípidos
MY159370A (en) * 2004-10-20 2016-12-30 Coley Pharm Group Inc Semi-soft-class immunostimulatory oligonucleotides
WO2007085962A2 (en) * 2006-01-26 2007-08-02 Pfizer Products Inc. Novel glycolipid adjuvant compositions
KR101333852B1 (ko) * 2008-06-27 2013-11-27 조에티스 엘엘씨 신규한 면역증강 조성물
DK2424562T3 (en) 2009-04-30 2015-12-07 Coley Pharm Group Inc Pneumococcal vaccine and uses thereof
MX2012002639A (es) * 2009-09-03 2012-03-14 Pfizer Vaccines Llc Vacuna de pcsk9.
LT2575878T (lt) * 2010-05-28 2018-11-12 Zoetis Belgium S.A. Vakcinos, apimančios cholesterolio ir cpg, kaip vienintelio adjuvanto-nešiklio, molekules
WO2013004234A2 (en) * 2011-07-04 2013-01-10 Statens Serum Institut Methods for producing liposomes
CN102973506B (zh) * 2011-09-05 2015-06-03 中国科学院深圳先进技术研究院 阳离子脂质体及其制备方法
HRP20211452T1 (hr) * 2013-05-14 2021-12-24 Zoetis Services Llc Novi cjepivni pripravci koji sadrže imunostimulacijske oligonukleotide
BR112016005948A2 (pt) * 2013-09-19 2017-09-26 Zoetis Services Llc adjuvantes com base em óleo
FR3012964A1 (fr) * 2013-11-12 2015-05-15 Seppic Sa Vaccins adjuves pour vaccination aviaire in ovo

Also Published As

Publication number Publication date
SI3325015T1 (sl) 2021-08-31
HK1250338A1 (zh) 2018-12-14
UA125017C2 (uk) 2021-12-29
CO2018000496A2 (es) 2018-04-19
BR112018001318A2 (pt) 2018-09-11
CA2992892C (en) 2019-12-31
CY1124319T1 (el) 2022-07-22
PT3325015T (pt) 2021-07-08
RS62015B1 (sr) 2021-07-30
HUE054422T2 (hu) 2021-09-28
LT3325015T (lt) 2021-08-10
JP2018524388A (ja) 2018-08-30
CN107847603A (zh) 2018-03-27
AU2016297529B2 (en) 2021-09-09
AU2016297529A1 (en) 2018-02-01
KR20180025977A (ko) 2018-03-09
NZ739040A (en) 2021-06-25
DK3325015T3 (da) 2021-07-05
EP3325015B1 (en) 2021-05-12
MX2018000879A (es) 2018-05-15
RU2018102114A (ru) 2019-08-20
JP6975132B2 (ja) 2021-12-01
WO2017015252A1 (en) 2017-01-26
RU2736642C2 (ru) 2020-11-19
ZA201800285B (en) 2019-07-31
CN107847603B (zh) 2021-05-11
CA2992892A1 (en) 2017-01-26
RU2018102114A3 (es) 2019-12-23
ES2878475T3 (es) 2021-11-18
TWI655002B (zh) 2019-04-01
BR112018001318B1 (pt) 2023-11-14
HRP20210872T1 (hr) 2021-07-09
PL3325015T3 (pl) 2021-10-25
KR102085968B1 (ko) 2020-03-06
EP3325015A1 (en) 2018-05-30
PH12018500146A1 (en) 2018-07-23
AR105393A1 (es) 2017-09-27
TW201711675A (zh) 2017-04-01

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