CL2008003202A1 - Composicion inmunogenica que comprende bacterias vivas de mycoplasma bovis atenuada avirulenta. - Google Patents

Composicion inmunogenica que comprende bacterias vivas de mycoplasma bovis atenuada avirulenta.

Info

Publication number
CL2008003202A1
CL2008003202A1 CL2008003202A CL2008003202A CL2008003202A1 CL 2008003202 A1 CL2008003202 A1 CL 2008003202A1 CL 2008003202 A CL2008003202 A CL 2008003202A CL 2008003202 A CL2008003202 A CL 2008003202A CL 2008003202 A1 CL2008003202 A1 CL 2008003202A1
Authority
CL
Chile
Prior art keywords
strain
bovis
immunogenic composition
mycoplasma bovis
live attenuated
Prior art date
Application number
CL2008003202A
Other languages
English (en)
Inventor
Michael Beck
Jeffrey KNITTEL
Original Assignee
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica Inc
Publication of CL2008003202A1 publication Critical patent/CL2008003202A1/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/36—Adaptation or attenuation of cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/0241—Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04—Inactivation or attenuation; Producing viral sub-units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/35—Mycoplasma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Otolaryngology (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)

Abstract

LA PRESENTE INVENCIÓN SE REFIERE A UNA VACUNA QUE COMPRENDE CEPAS BACTERIANAS DE MYCOPLASMA BOVIS ATENUADA AVIRULENTA, DONDE DICHA CEPA SE SELECCIONA DEL GRUPO QUE CONSISTE DE: A) LA CEPA BACTERIANA DE M. BOVIS ATENUADA DEPOSITADA EN LA ATCC CON EL NÚMERO DE ACCESO PTA-8694, B) CUALQUIER CEPA BACTERIANA DE M. BOVIS DESCENDIENTE DE LA CEPA DEPOSITADA EN LA ATCC CON EL NÚMERO DE ACCESO PTA-8694, CAPAZ DE INDUCIR UNA RESPUESTA INMUNE HUMORAL EN UN TERNERO DENTRO DE LOS 14 DIAS DESPUÉS DE LA ADMINISTRACIÓN DE UNA DOSIS VÍA SUBCUTÁNEA O RUTA INTRANASAL DE UN TERNERO, Y DE NO CAUSAR SIGNOS CLÍNICOS NORMALMENTE CAUSADOS POR UNA INFECCIÓN CON UNA CEPA SILVESTRE DE M. BOVIS.
CL2008003202A 2007-10-29 2008-10-28 Composicion inmunogenica que comprende bacterias vivas de mycoplasma bovis atenuada avirulenta. CL2008003202A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98348207P 2007-10-29 2007-10-29
US7555208P 2008-06-25 2008-06-25

Publications (1)

Publication Number Publication Date
CL2008003202A1 true CL2008003202A1 (es) 2009-11-27

Family

ID=40591728

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2008003202A CL2008003202A1 (es) 2007-10-29 2008-10-28 Composicion inmunogenica que comprende bacterias vivas de mycoplasma bovis atenuada avirulenta.

Country Status (14)

Country Link
US (1) US8652481B2 (es)
EP (1) EP2214702B1 (es)
JP (2) JP2011500093A (es)
KR (2) KR20160095185A (es)
CN (2) CN103667125A (es)
AR (1) AR069087A1 (es)
BR (1) BRPI0819149B1 (es)
CA (1) CA2699218C (es)
CL (1) CL2008003202A1 (es)
MX (1) MX2010003719A (es)
NZ (1) NZ585588A (es)
SG (1) SG185932A1 (es)
UY (1) UY31437A1 (es)
WO (1) WO2009058833A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110059437A1 (en) * 2006-09-07 2011-03-10 Boehringer Ingelheim Vetmedica, Inc. Pcr-based genotyping
AR069087A1 (es) 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
US8503527B2 (en) 2008-10-03 2013-08-06 Qualcomm Incorporated Video coding with large macroblocks
US8815255B2 (en) * 2008-10-31 2014-08-26 Boehringer Ingelheim Vetmedica, Inc. Use of Mycoplasma bovis antigen
UY32570A (es) * 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
AU2013370983B2 (en) 2012-12-28 2019-09-26 Boehringer Ingelheim Vetmedica Gmbh Method of making a mycoplasma vaccine
UA121097C2 (uk) * 2012-12-28 2020-04-10 Бьорінгер Інгельхайм Ветмедіка Гмбх Імуногенна композиція, що містить антигени мікоплазм
WO2017030901A1 (en) * 2015-08-14 2017-02-23 Zoetis Services Llc Mycoplasma bovis compositions
CN105441368B (zh) * 2016-01-19 2019-01-01 福清市默克兽医院 一株牛支原体及其应用
CN107118262A (zh) * 2016-02-24 2017-09-01 华中农业大学 一种牛支原体MbovP579蛋白及其应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
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US7007A (en) * 1850-01-08 Improvement in machinery for making cotton cordage
US2909462A (en) 1955-12-08 1959-10-20 Bristol Myers Co Acrylic acid polymer laxative compositions
WO1999002670A1 (en) * 1997-07-10 1999-01-21 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Method of attenuating pathogenic mycobacteria and strains of mycobacteria so attenuated
EP0965639A1 (en) 1998-06-05 1999-12-22 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
ES2322327T3 (es) * 1999-03-26 2009-06-19 Walter Reed Army Institute Of Research Vacuna multivalente contra el virus del dengue.
MXPA02004627A (es) 1999-11-08 2004-02-18 Biomune Vacunas contra el micoplasma bovis y sus metodos de uso.
US6548069B2 (en) 2001-02-03 2003-04-15 Hmv Associates, Inc. Multivalent Mycoplasma bacterin
JP2004537543A (ja) * 2001-07-02 2004-12-16 ファイザー・プロダクツ・インク マイコプラズマ・ハイオニューモニエ・ワクチンおよび牛におけるマイコプラズマ・ボビス低減方法
US20030147914A1 (en) 2001-07-02 2003-08-07 Pfizer Inc. Mycoplasma bovis vaccine and methods of reducing pneumonia in animals
WO2003017755A2 (en) 2001-08-28 2003-03-06 Pfizer Products Inc. Mycoplasma bovis challenge model, methods for administering m.bovis and methods for inducing pneumonic lung lesions
DE102004025452A1 (de) 2004-05-19 2006-01-19 Boehringer Ingelheim Vetmedica Gmbh Vakzine enthaltend BVDV
US20070009545A1 (en) * 2005-07-07 2007-01-11 Joachim Frey Mycoplasma subunit vaccine
US20110059437A1 (en) * 2006-09-07 2011-03-10 Boehringer Ingelheim Vetmedica, Inc. Pcr-based genotyping
US20090068231A1 (en) * 2007-09-11 2009-03-12 Wyeth Live attenuated mycoplasma strains
AR069087A1 (es) 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
WO2010002537A1 (en) 2008-07-03 2010-01-07 Iowa State University Research Foundation, Inc. Cattle vaccines
US8815255B2 (en) 2008-10-31 2014-08-26 Boehringer Ingelheim Vetmedica, Inc. Use of Mycoplasma bovis antigen
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada

Also Published As

Publication number Publication date
WO2009058833A2 (en) 2009-05-07
CN101827605A (zh) 2010-09-08
CA2699218A1 (en) 2009-05-07
AR069087A1 (es) 2009-12-30
KR101656301B1 (ko) 2016-09-12
JP2011500093A (ja) 2011-01-06
SG185932A1 (en) 2012-12-28
KR20160095185A (ko) 2016-08-10
AU2008318793A1 (en) 2009-05-07
US20090130148A1 (en) 2009-05-21
US8652481B2 (en) 2014-02-18
UY31437A1 (es) 2009-05-29
CN103667125A (zh) 2014-03-26
JP2013223511A (ja) 2013-10-31
BRPI0819149B1 (pt) 2021-11-23
EP2214702A2 (en) 2010-08-11
EP2214702B1 (en) 2018-07-04
KR20100084626A (ko) 2010-07-27
BRPI0819149A2 (pt) 2020-08-25
EP2214702A4 (en) 2010-12-22
CN101827605B (zh) 2016-05-04
MX2010003719A (es) 2010-04-27
WO2009058833A3 (en) 2009-06-18
NZ585588A (en) 2012-09-28
JP5789897B2 (ja) 2015-10-07
CA2699218C (en) 2019-09-10

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