CL2007003108A1 - Compuestos derivados de n-hidroxiamida sustituida con heterociclos, inhibidores de histona desacetilasa; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad del grupo que consiste en enfermedad de huntington, - Google Patents

Compuestos derivados de n-hidroxiamida sustituida con heterociclos, inhibidores de histona desacetilasa; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad del grupo que consiste en enfermedad de huntington,

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Publication number
CL2007003108A1
CL2007003108A1 CL200703108A CL2007003108A CL2007003108A1 CL 2007003108 A1 CL2007003108 A1 CL 2007003108A1 CL 200703108 A CL200703108 A CL 200703108A CL 2007003108 A CL2007003108 A CL 2007003108A CL 2007003108 A1 CL2007003108 A1 CL 2007003108A1
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CL
Chile
Prior art keywords
disease
compounds
heterocicles
hydroxyamide
huntington
Prior art date
Application number
CL200703108A
Other languages
English (en)
Inventor
Deziel Silvana Leit Pat Robert
Original Assignee
Methylgene Inc Envivo Pharmace
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Publication date
Application filed by Methylgene Inc Envivo Pharmace filed Critical Methylgene Inc Envivo Pharmace
Publication of CL2007003108A1 publication Critical patent/CL2007003108A1/es

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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
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    • A—HUMAN NECESSITIES
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