CL2007001467A1 - Uso de agentes antiepilepticos o anticonvulsivantes y un compuesto derivado de heterociclil-alquil-sulfamida para tratar la epilepsia o un trastorno relacionado. - Google Patents
Uso de agentes antiepilepticos o anticonvulsivantes y un compuesto derivado de heterociclil-alquil-sulfamida para tratar la epilepsia o un trastorno relacionado.Info
- Publication number
- CL2007001467A1 CL2007001467A1 CL200701467A CL2007001467A CL2007001467A1 CL 2007001467 A1 CL2007001467 A1 CL 2007001467A1 CL 200701467 A CL200701467 A CL 200701467A CL 2007001467 A CL2007001467 A CL 2007001467A CL 2007001467 A1 CL2007001467 A1 CL 2007001467A1
- Authority
- CL
- Chile
- Prior art keywords
- sulfamida
- anticonvulsiving
- heterociclil
- alquil
- antiepileptic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/22—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one naphthalene or hydrogenated naphthalene ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80200006P | 2006-05-19 | 2006-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2007001467A1 true CL2007001467A1 (es) | 2008-03-14 |
Family
ID=38561914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL200701467A CL2007001467A1 (es) | 2006-05-19 | 2007-05-22 | Uso de agentes antiepilepticos o anticonvulsivantes y un compuesto derivado de heterociclil-alquil-sulfamida para tratar la epilepsia o un trastorno relacionado. |
Country Status (11)
Country | Link |
---|---|
US (1) | US8853263B2 (es) |
EP (1) | EP2026790A2 (es) |
JP (1) | JP2009537635A (es) |
AR (1) | AR061067A1 (es) |
AU (1) | AU2007253814A1 (es) |
CL (1) | CL2007001467A1 (es) |
EA (1) | EA200870556A1 (es) |
PE (1) | PE20080716A1 (es) |
TW (1) | TW200812573A (es) |
UY (1) | UY30359A1 (es) |
WO (1) | WO2007137167A2 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11660275B2 (en) | 2018-03-20 | 2023-05-30 | Eisai R&D Management Co., Ltd. | Epilepsy treatment agent |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
CN101090896B (zh) * | 2004-08-24 | 2011-10-26 | 詹森药业有限公司 | 用作抗惊厥药的苯并稠合杂芳基氨基磺酰胺衍生物 |
WO2006127184A1 (en) | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
US8497298B2 (en) * | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US8716231B2 (en) * | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US8492431B2 (en) * | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US8691867B2 (en) * | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
US20070155823A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
US20070191474A1 (en) * | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
US8853263B2 (en) | 2006-05-19 | 2014-10-07 | Janssen Pharmaceutica Nv | Co-therapy for the treatment of epilepsy and related disorders |
US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
WO2009133107A1 (en) * | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
ATE522515T1 (de) * | 2008-04-29 | 2011-09-15 | Nsab Af Neurosearch Sweden Ab | Modulatoren der dopamin-neurotransmission |
EP2271635A1 (en) * | 2008-04-29 | 2011-01-12 | NSAB, Filial af NeuroSearch Sweden AB, Sverige | Modulators of dopamine neurotransmission |
EA018567B1 (ru) | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
US8815939B2 (en) | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
DE102009049662A1 (de) | 2009-10-13 | 2011-04-14 | Bayer Schering Pharma Aktiengesellschaft | 2,5-Disubstituierte 2H-Indazole als EP2-Rezeptor-Antagonisten |
CA2850513A1 (en) | 2011-09-29 | 2013-04-04 | Janssen Pharmaceutica Nv | Process for the preparation of sulfamide derivatives |
US8895762B2 (en) | 2011-09-29 | 2014-11-25 | Janssen Pharmaceutica Nv | Process for the preparation of sulfamide derivatives |
US8652527B1 (en) | 2013-03-13 | 2014-02-18 | Upsher-Smith Laboratories, Inc | Extended-release topiramate capsules |
US9101545B2 (en) | 2013-03-15 | 2015-08-11 | Upsher-Smith Laboratories, Inc. | Extended-release topiramate capsules |
US9937145B2 (en) * | 2013-12-12 | 2018-04-10 | Bio-Pharm Solutions Co., Ltd. | Sulfamate derivative compound for use in preventing or treating epilepsy |
EP3193862B1 (en) | 2014-09-16 | 2023-10-18 | Igc Pharma Ip, Llc | Topical cannabinoid composition for treating arthritic pain |
US10751300B2 (en) | 2015-01-25 | 2020-08-25 | India Globalization Capital, Inc. | Composition and method for treating seizure disorders |
WO2016160542A1 (en) * | 2015-04-01 | 2016-10-06 | India Globalization Capital, Inc. | Composition and method for treating seizure disorders |
US10596159B2 (en) | 2015-08-12 | 2020-03-24 | India Globalization Capital, Inc. | Method and composition for treating cachexia and eating disorders |
CA3027862A1 (en) | 2016-06-15 | 2017-12-21 | India Globalization Capital, Inc. | Method and composition for treating seizure disorders |
CN110072521B (zh) * | 2016-12-16 | 2022-11-29 | 爱杜西亚药品有限公司 | 包含t型钙通道阻断剂的药物组合 |
CN113234547A (zh) * | 2021-05-26 | 2021-08-10 | 德州竹洋洗涤科技有限公司 | 一种织物高效去污剂 |
Family Cites Families (123)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2527861A (en) * | 1948-05-07 | 1950-10-31 | Monsanto Chemicals | Mono alkyl sulfamides |
BE636655A (es) * | 1962-09-14 | |||
DE1211166B (de) | 1962-11-20 | 1966-02-24 | Ciba Geigy | Verfahren zur Herstellung neuer Sulfamide |
US3318952A (en) * | 1964-01-22 | 1967-05-09 | Sandoz Ag | Dibenzylsulfamides |
US3320314A (en) | 1964-01-22 | 1967-05-16 | Sandoz Ag | Chlorobenzyl sulfamides |
US3383414A (en) * | 1964-08-26 | 1968-05-14 | Sandoz Ag | Benzocycloalkyl sulfamides |
DE1542785A1 (de) | 1965-07-24 | 1970-05-06 | Bayer Ag | Insekten- und milbenabweisende Mittel |
US3539573A (en) * | 1967-03-22 | 1970-11-10 | Jean Schmutz | 11-basic substituted dibenzodiazepines and dibenzothiazepines |
US3621096A (en) * | 1969-04-03 | 1971-11-16 | Univ North Carolina | Antidepressant method and composition for same comprising a tricyclic antidepressant and a thyroid hormone |
DE2022370A1 (de) | 1970-05-08 | 1971-12-02 | Bayer Ag | N-Fluordichlormethylthio-sulfamidsaeure-Derivate,Verfahren zu ihrer Herstellung und ihre mikrobizide und fungizide Verwendung |
US5212326A (en) * | 1979-08-20 | 1993-05-18 | Abbott Laboratories | Sodium hydrogen divalproate oligomer |
FR2479825A1 (fr) * | 1980-04-04 | 1981-10-09 | Fabre Sa Pierre | Benzodioxanne 1,4 methoxy-2 propanolamines, leur preparation et leur application en tant que medicaments |
US4513006A (en) | 1983-09-26 | 1985-04-23 | Mcneil Lab., Inc. | Anticonvulsant sulfamate derivatives |
US4804663A (en) * | 1985-03-27 | 1989-02-14 | Janssen Pharmaceutica N.V. | 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles |
IE58370B1 (en) * | 1985-04-10 | 1993-09-08 | Lundbeck & Co As H | Indole derivatives |
GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
US4831031A (en) * | 1988-01-22 | 1989-05-16 | Pfizer Inc. | Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity |
US5158952A (en) * | 1988-11-07 | 1992-10-27 | Janssen Pharmaceutica N.V. | 3-[2-[4-(6-fluoro-1,2-benzisoxozol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9 tetrahydro-9-hydroxy-2-methyl-4H-pyrido [1,2-a]pyrimidin-4-one, compositions and method of use |
GB8908085D0 (en) * | 1989-04-11 | 1989-05-24 | Lundbeck & Co As H | New therapeutic use |
US5238945A (en) * | 1989-04-11 | 1993-08-24 | H. Lundbeck A/S | Method of treating psychoses |
US5194446A (en) * | 1989-06-12 | 1993-03-16 | A. H. Robins Company, Incorporated | Compounds having one or more aminosulfaonyloxy radicals useful as pharmaceuticals |
US5273993A (en) * | 1989-06-12 | 1993-12-28 | A. H. Robins Company, Incorporated | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals |
US5192785A (en) * | 1989-09-03 | 1993-03-09 | A. H. Robins Company, Incorporated | Sulfamates as antiglaucoma agents |
US5229382A (en) * | 1990-04-25 | 1993-07-20 | Lilly Industries Limited | 2-methyl-thieno-benzodiazepine |
US5189179A (en) | 1990-08-29 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | Serotonin 5ht1a agonists |
CA2054339C (en) | 1990-11-02 | 2002-12-24 | Francesco G. Salituro | 3-amidoindolyl derivatives |
GB9026998D0 (en) | 1990-12-12 | 1991-01-30 | Glaxo Group Ltd | Medicaments |
US5120758A (en) | 1991-02-08 | 1992-06-09 | Ciba-Geigy Corporation | Certain benzodioxole, benzodioxane and benzodioxepin derivatives useful as 5-lipoxygenase inhibitors |
GB9104890D0 (en) | 1991-03-08 | 1991-04-24 | Glaxo Group Ltd | Compositions |
IL103172A (en) * | 1991-09-19 | 1997-01-10 | Mcneilab Inc | Preparation of chlorosulfate and sulfamate derivatives of 2, 3:4, 5-bis-o-(1-methylethylidene)-beta-d-fructopyranose and (1-methylcyclohexyl) methanol |
US5242942A (en) * | 1992-04-28 | 1993-09-07 | Mcneilab, Inc. | Anticonvulsant fructopyranose cyclic sulfites and sulfates |
US5258402A (en) * | 1992-06-11 | 1993-11-02 | Mcneil-Ppc, Inc. | Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates |
US5312925A (en) * | 1992-09-01 | 1994-05-17 | Pfizer Inc. | Monohydrate of 5-(2-(4-(1,2-benzisothiazol-3-yl)-1-piperazinyl)-ethyl)-6-chloro-1,3-dihydro-2H-indol-2-one-hydrochloride |
US5384327A (en) | 1992-12-22 | 1995-01-24 | Mcneilab, Inc. | Anticonvulsant sorbopyranose sulfamates |
DK0736029T3 (da) | 1993-12-23 | 2006-05-15 | Ortho Mcneil Pharm Inc | Antikonvulsive pseudofructopyranosesulfamater |
GB9417532D0 (en) | 1994-08-31 | 1994-10-19 | Zeneca Ltd | Aromatic compounds |
CA2216648A1 (en) * | 1995-02-15 | 1996-08-22 | Bearsden Bio, Inc. | Alkylcarboxy amino acids-modulators of the kainate receptor |
JP3235448B2 (ja) * | 1995-03-24 | 2001-12-04 | ダイソー株式会社 | 1,4−ベンゾジオキサン誘導体の製法 |
US5998380A (en) * | 1995-10-13 | 1999-12-07 | New England Medical Center Hospitals, Inc. | Treatment of migraine |
WO1997019919A1 (fr) | 1995-11-30 | 1997-06-05 | C & C Research Laboratories | Derives de sulfamides |
AU1328197A (en) | 1995-12-01 | 1997-06-19 | Synaptic Pharmaceutical Corporation | Aryl sulfonamide and sulfamide derivatives and uses thereof |
EP0906104A4 (en) | 1996-03-25 | 2003-12-10 | Lilly Co Eli | PAIN TREATMENT PROCESS |
US5753694A (en) | 1996-06-28 | 1998-05-19 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating amyotrophic lateral sclerosis (ALS) |
WO1998000124A1 (en) | 1996-06-28 | 1998-01-08 | Ortho Pharmaceutical Corporation | Use of topiramate or derivatives thereof for the manufacture of a medicament for the treatment of postischemic neurodegeneration |
US5753693A (en) * | 1996-06-28 | 1998-05-19 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder |
CA2258893C (en) * | 1996-06-28 | 2005-06-14 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant sulfamate derivatives useful in treating obesity |
IL128255A (en) | 1996-08-14 | 2004-06-20 | Searle & Co | Crystal form of –4 [–5 methyl –– 3 phenylisoxazole ––4yl] benzenesulfonamide |
WO1998007447A1 (en) * | 1996-08-23 | 1998-02-26 | Algos Pharmaceutical Corporation | Anticonvulsant containing composition for treating neuropathic pain |
CZ296525B6 (cs) | 1996-10-08 | 2006-04-12 | Ortho-Mcneil Pharmaceutical, Inc. | Lécivo pro lécení neuropatické bolesti |
US20020015713A1 (en) * | 1996-10-24 | 2002-02-07 | Murdock Robert W. | Methods and transdermal compositions for pain relief |
US5935933A (en) * | 1997-07-16 | 1999-08-10 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating neuropathic pain |
US5760007A (en) * | 1997-07-16 | 1998-06-02 | Ortho Pharmaceutical Corporation | Anticonvulsant derivatives useful in treating neuropathic pain |
WO1999008669A1 (en) * | 1997-08-15 | 1999-02-25 | Carolyn Ann Fairbanks | Agmatine as a treatment for neuropathic pain |
GB9803536D0 (en) | 1998-02-19 | 1998-04-15 | Black James Foundation | Histamine H,receptor ligands |
UA65607C2 (uk) | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
DK72798A (da) | 1998-05-28 | 1998-05-28 | Novo Nordisk As | Treatment of GABA-uptake related disorders |
SK17492000A3 (sk) | 1998-05-29 | 2002-04-04 | Eli Lilly And Company | Liek na liečenie bipolárnych porúch a farmaceutický prostriedok |
JP2002519373A (ja) | 1998-07-02 | 2002-07-02 | エーザイ株式会社 | 製薬組成物及びそれらの使用 |
US6541520B1 (en) | 1998-08-05 | 2003-04-01 | Brookhaven Science Associates | Treatment of addiction and addiction-related behavior |
ES2228465T3 (es) * | 1999-01-19 | 2005-04-16 | Ortho-Mcneil Pharmaceutical, Inc. | Uso derivados anticonvulsionantes para el tratamiento de cefaleas en brotes. |
AU3582600A (en) | 1999-01-21 | 2000-08-07 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in treating transformed migraine |
GB9903784D0 (en) | 1999-02-18 | 1999-04-14 | Lilly Co Eli | Pharmaceutical compounds |
JP2002537326A (ja) * | 1999-02-24 | 2002-11-05 | ユニヴァーシティ・オブ・シンシナティ | 衝動調節障害の治療のためのスルファメート誘導体の使用 |
EP1124416A1 (en) | 1999-03-15 | 2001-08-22 | John Claude Krusz | Treatment of acute headaches and chronic pain using rapidly-cleared anesthetic drug at sub-anesthetic dosages |
MXPA01010217A (es) * | 1999-04-08 | 2005-09-08 | Johnson & Johnson | Derivados anticonvulsivos utiles en el tratamiento de trastornos neurodegenerativos cronicos. |
NZ514811A (en) | 1999-04-08 | 2005-01-28 | Ortho Mcneil Pharm Inc | Anticonvulsant derivatives useful in reducing blood glucose levels |
JP2002541199A (ja) | 1999-04-08 | 2002-12-03 | オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド | 脂質を下げることに有用な抗痙攣薬誘導体 |
WO2000061140A1 (en) | 1999-04-08 | 2000-10-19 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful in maintaining weight loss |
AU4703500A (en) | 1999-05-04 | 2000-11-17 | Keith R. Edwards | Intravenous valproate for acute treatment of migraine headache |
CA2377330C (en) | 1999-06-14 | 2009-11-24 | Thomas Najarian | Combination therapy for effecting weight loss and treating obesity |
ES2234651T3 (es) | 1999-08-20 | 2005-07-01 | Ortho-Mcneil Pharmaceutical, Inc. | Composicion que comprende una materia de tramadol y un farmaco anticonvulsivo. |
FR2803848B1 (fr) | 2000-01-19 | 2002-02-15 | Adir | Nouveaux derives de benzenesulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6322503B1 (en) * | 2000-02-17 | 2001-11-27 | G. Roger Sparhawk, Jr. | Method of diagnosing, tracking, and treating depression |
US20010036943A1 (en) | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
JP4920163B2 (ja) * | 2000-07-07 | 2012-04-18 | オーソーマクニール ファーマシューティカル, インコーポレイテッド | Ii型糖尿病およびx症候群の進行を防止するのに有用な鎮痙剤誘導体 |
DE10035227A1 (de) | 2000-07-20 | 2002-01-31 | Solvay Pharm Gmbh | Verfahren zum Auffinden von Verbindungen, welche zur Behandlung und/oder Prophylaxe von Fettleibigkeit geeignet sind |
AU2001280865A1 (en) | 2000-08-02 | 2002-02-13 | Ortho-Mcneil Pharmaceutical, Inc. | Anticonvulsant derivatives useful for the treatment of depression |
PE20021046A1 (es) | 2000-09-30 | 2002-12-14 | Gruenenthal Chemie | Sulfonilguanidina que tiene afinidad al punto de fijacion de gabapentina |
US7256184B2 (en) | 2000-10-16 | 2007-08-14 | Rodriguez Victorio C | Treatment of aging disorders in humans |
JP4181408B2 (ja) * | 2001-01-30 | 2008-11-12 | メルク エンド カムパニー インコーポレーテッド | 肥満、糖尿病及び脂質異常を治療するためのアシルスルファミド類 |
WO2002089785A1 (en) | 2001-05-07 | 2002-11-14 | Smithkline Beecham Corporation | Sulfonamides |
JP2004536071A (ja) | 2001-05-25 | 2004-12-02 | クイーンズ ユニバーシティ アット キングストン | 複素環ベータアミノ酸およびそれらの抗癲癇誘発剤としての使用 |
US20030100594A1 (en) | 2001-08-10 | 2003-05-29 | Pharmacia Corporation | Carbonic anhydrase inhibitor |
US6559293B1 (en) * | 2002-02-15 | 2003-05-06 | Transform Pharmaceuticals, Inc. | Topiramate sodium trihydrate |
US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
RU2246727C2 (ru) | 2003-02-12 | 2005-02-20 | Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М. Бехтерева (НИПИ) | Способ диагностики доклинической стадии эпилепсии |
RU2226357C1 (ru) | 2003-02-12 | 2004-04-10 | Санкт-Петербургский научно-исследовательский психоневрологический институт им. В.М.Бехтерева | Способ диагностики эпилепсии у пациентов с доклинической стадией болезни |
MXPA05010884A (es) | 2003-04-10 | 2007-01-15 | Amgen Inc | Compuestos biciclicos que tienen afinidad por receptores de bradicinina y composiciones farmaceuticas de los mismos. |
AU2003223634A1 (en) | 2003-04-16 | 2004-11-26 | Siegfried B. Christensen Iv | Peptide deformylase inhibitors |
WO2004093912A1 (ja) | 2003-04-23 | 2004-11-04 | Kyowa Hakko Kogyo Co. Ltd. | 好中球性炎症疾患の予防および/または治療剤 |
GB0309781D0 (en) | 2003-04-29 | 2003-06-04 | Glaxo Group Ltd | Compounds |
US6949518B1 (en) | 2003-06-25 | 2005-09-27 | Pao-Hsien Chu | Methods for treating macular degeneration with topiramate |
CA2537119A1 (en) | 2003-09-02 | 2005-03-10 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
CN1897950A (zh) * | 2003-10-14 | 2007-01-17 | 惠氏公司 | 稠合芳基和杂芳基衍生物及其使用方法 |
TW200612905A (en) * | 2004-06-16 | 2006-05-01 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
WO2006010008A1 (en) | 2004-06-22 | 2006-01-26 | Vertex Pharmaceuticals Incorporated | Heterocyclic derivatives for modulation of calcium channels |
WO2006010750A1 (en) | 2004-07-28 | 2006-02-02 | Janssen Pharmaceutica N.V. | Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
US20060276528A1 (en) * | 2004-08-24 | 2006-12-07 | Abdel-Magid Ahmed F | Novel benzo-fused heteroaryl sulfamide derivatives useful as anticonvulsant agents |
CN101090896B (zh) * | 2004-08-24 | 2011-10-26 | 詹森药业有限公司 | 用作抗惊厥药的苯并稠合杂芳基氨基磺酰胺衍生物 |
GT200600159A (es) * | 2005-04-22 | 2007-03-14 | Derivados benzodioxano y benzodioxolano y usos de los mismos | |
WO2006127184A1 (en) | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
US20070155823A1 (en) | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives as neuroprotective agents |
US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
US20070155824A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for disease modification / epileptogenesis |
US8492431B2 (en) | 2005-12-19 | 2013-07-23 | Janssen Pharmaceutica, N.V. | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of obesity |
US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
US20070155827A1 (en) | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
US8716231B2 (en) | 2005-12-19 | 2014-05-06 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
US20070191474A1 (en) | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of migraine |
US20070191452A1 (en) | 2006-02-15 | 2007-08-16 | Smith-Swintosky Virginia L | Use of benzo-heteroaryl sulfamide derivatives for the treatment of pain |
TW200738669A (en) | 2006-02-22 | 2007-10-16 | Janssen Pharmaceutica Nv | Crystalline forms of N-(benzo[b]thien-3-ylmethyl)-sulfamide |
WO2007137164A2 (en) * | 2006-05-19 | 2007-11-29 | Janssen Pharmaceutica N.V. | Co-therapy for the treatment of epilepsy and related disorders |
US8853263B2 (en) | 2006-05-19 | 2014-10-07 | Janssen Pharmaceutica Nv | Co-therapy for the treatment of epilepsy and related disorders |
WO2008061903A1 (en) * | 2006-11-22 | 2008-05-29 | Agfa Healthcate Inc. | Method and system for client / server distributed image processing |
US20090182141A1 (en) * | 2008-01-07 | 2009-07-16 | Ahmed Abdel-Magid | Process for the preparation of sulfamide derivatives |
CN101981023A (zh) | 2008-03-26 | 2011-02-23 | 詹森药业有限公司 | 用于制备苯并稠合二噁英衍生物的方法 |
US20090247618A1 (en) * | 2008-03-26 | 2009-10-01 | Ballentine Scott A | Process for preparation of benzo-fused heteroaryl derivatives |
AU2008353491A1 (en) | 2008-03-26 | 2009-10-01 | Janssen Pharmaceutica N.V. | Process for the preparation of benzo-fused heteroaryl sulfamates and crystalline form of N- ( ( (2S) -6-chloro-2,3-dihydro-l,4-benzodioxin-2-yl) methyl-sulfamide |
US20090247617A1 (en) | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
EA018567B1 (ru) * | 2008-06-23 | 2013-08-30 | Янссен Фармацевтика Нв | Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида |
US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
-
2007
- 2007-05-18 US US11/750,600 patent/US8853263B2/en not_active Expired - Fee Related
- 2007-05-18 EA EA200870556A patent/EA200870556A1/ru unknown
- 2007-05-18 JP JP2009512233A patent/JP2009537635A/ja not_active Withdrawn
- 2007-05-18 AU AU2007253814A patent/AU2007253814A1/en not_active Abandoned
- 2007-05-18 EP EP07783932A patent/EP2026790A2/en not_active Withdrawn
- 2007-05-18 TW TW096117856A patent/TW200812573A/zh unknown
- 2007-05-18 WO PCT/US2007/069254 patent/WO2007137167A2/en active Application Filing
- 2007-05-21 PE PE2007000618A patent/PE20080716A1/es not_active Application Discontinuation
- 2007-05-21 AR ARP070102202A patent/AR061067A1/es not_active Application Discontinuation
- 2007-05-22 UY UY30359A patent/UY30359A1/es unknown
- 2007-05-22 CL CL200701467A patent/CL2007001467A1/es unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11660275B2 (en) | 2018-03-20 | 2023-05-30 | Eisai R&D Management Co., Ltd. | Epilepsy treatment agent |
Also Published As
Publication number | Publication date |
---|---|
WO2007137167A2 (en) | 2007-11-29 |
PE20080716A1 (es) | 2008-07-19 |
US8853263B2 (en) | 2014-10-07 |
AR061067A1 (es) | 2008-07-30 |
EP2026790A2 (en) | 2009-02-25 |
AU2007253814A1 (en) | 2007-11-29 |
WO2007137167A3 (en) | 2008-02-28 |
US20070293440A1 (en) | 2007-12-20 |
JP2009537635A (ja) | 2009-10-29 |
TW200812573A (en) | 2008-03-16 |
EA200870556A1 (ru) | 2009-06-30 |
UY30359A1 (es) | 2007-08-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CL2007001467A1 (es) | Uso de agentes antiepilepticos o anticonvulsivantes y un compuesto derivado de heterociclil-alquil-sulfamida para tratar la epilepsia o un trastorno relacionado. | |
CL2007001468A1 (es) | Uso de uno o varios agentes antiepilepticos o anticonvulsivantes y de un compuesto derivado de benzoheteroaril-sulfamida para tratar epilepsia o un trastorno relacionado. | |
CL2007002455A1 (es) | Compuestos derivados de 2-fenil-3,4-dihidro-1h-isoquinolina, moduladores de canales de potasio; compuesto intermediario; composicion farmaceutica; y uso para prevenir o tratar un trastorno provocado por hiperexcitabilidad del sistema nervioso, tal co | |
CL2008000691A1 (es) | Compuestos derivados de dihidro y tetrahidro oxazolopirimidinonas sustituidas; composicion farmaceutica que comprende a dichos compuestos; y su uso para el tratamiento de la esquizofrenia, epilepsia, entre otras enfermedades. | |
BRPI0924425A2 (pt) | "combinações de substâncias ativas sinergéticas". | |
BRPI1007990A2 (pt) | Compostos específicos de diaril-hidantoína e diariltioidantoína. | |
BRPI0818244A2 (pt) | Composto, composição farmacêutica, uso de um composto, e, método para tratamento de um distúrbio ou doença | |
DK2134201T3 (da) | Flerkomponentfilter som tilvejebringer forbedret smagsforstærkning | |
BRPI0610514A2 (pt) | composto, composição farmacêutica, e, método de tratamento de um distúrbio | |
CL2014000366A1 (es) | Composicion resistente a la contaminacion que comprende un elastomero y un componente seleccionado de lanolina acilada, lanolina alcoxilada o aceite de lanolina; metodo; uso de la composicion; y sustrato. | |
BRPI0922597A2 (pt) | "ftalazinona e análogos relacionados como moduladores de sirtuína". | |
BRPI0719960A2 (pt) | Bocal efervescente para injenção de catalisador | |
DE602007001191D1 (de) | Öl-in-öl-emulsionen | |
CL2007002837A1 (es) | Uso de fenitoina para tratar mucositis oral. | |
CR10075A (es) | Bifenilcarboxamidas para combatir microorganismos. | |
BRPI0815994A2 (pt) | conjunto de retém do ferrolho-ejetor para armas de fogo | |
BRPI0811470A2 (pt) | Paralelização de estruturas sequenciais usando transações. | |
FR2938767B1 (fr) | Composition photoprotectrice contenant un amidon gelifiant et des particules de polyamide | |
BRPI0921546A2 (pt) | Compostos de arilazol-2-il cianoetilamina enriquecidos enantiomericamente, método para fabricação e método de uso dos mesmos | |
BRPI0719275A2 (pt) | Composições de carbamatos de fenil-alquil-amino | |
BRPI0607748A2 (pt) | composto, composição farmacêutica, e, método de tratamento de um distúrbio | |
FR2939728B1 (fr) | Agencement d'un composant et d'un element d'actionnement associe a ce composant. | |
BRPI0715728A2 (pt) | tratamento de distérbio cartilaginosos | |
IL212403A0 (en) | Carbamate compound or salt thereof | |
CL2007003162A1 (es) | Uso de compuestos derivados de vitamina d para prevenir, tratar o aminorar un desorden hiperproliferativo. |