CH541560A - Préparation de dérivés de la pyridine trisubstituée - Google Patents
Préparation de dérivés de la pyridine trisubstituéeInfo
- Publication number
- CH541560A CH541560A CH164872A CH541560DA CH541560A CH 541560 A CH541560 A CH 541560A CH 164872 A CH164872 A CH 164872A CH 541560D A CH541560D A CH 541560DA CH 541560 A CH541560 A CH 541560A
- Authority
- CH
- Switzerland
- Prior art keywords
- derivatives
- preparation
- trisubstituted pyridine
- trisubstituted
- pyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11587871A | 1971-02-16 | 1971-02-16 | |
US25664172A | 1972-05-25 | 1972-05-25 |
Publications (1)
Publication Number | Publication Date |
---|---|
CH541560A true CH541560A (fr) | 1973-10-31 |
Family
ID=26813670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CH164872A CH541560A (fr) | 1971-02-16 | 1972-02-04 | Préparation de dérivés de la pyridine trisubstituée |
Country Status (9)
Country | Link |
---|---|
US (2) | US3700681A (fr) |
AT (1) | AT315842B (fr) |
BE (1) | BE778771A (fr) |
CA (1) | CA978962A (fr) |
CH (1) | CH541560A (fr) |
DE (2) | DE2204195C2 (fr) |
FR (1) | FR2125309B1 (fr) |
GB (2) | GB1367669A (fr) |
NL (1) | NL174349C (fr) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR207639A1 (es) * | 1973-12-26 | 1976-10-22 | Pfizer | Un procedimiento para preparar pirido (3,2-d)1,3-dioxin-6-epoxietanos y compuestos intermediarios desprovistos de actividad terapeutica |
US3952101A (en) * | 1975-04-14 | 1976-04-20 | Smithkline Corporation | α-Amino methyl-5-hydroxy-2-pyridinemethanols |
US4011231A (en) * | 1975-10-03 | 1977-03-08 | Pfizer Inc. | 2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate |
SE7708307L (sv) * | 1976-08-26 | 1978-02-27 | Pfizer | Forfarande for framstellning av farmaceutiska kompositioner anvendbara sasom bronkodilatorer |
US4175128A (en) * | 1979-01-03 | 1979-11-20 | Pfizer Inc. | Method for treating congestive heart failure |
US4632992A (en) * | 1981-02-09 | 1986-12-30 | Pfizer Inc. | Intermediates for preparing pirbuterol and analogs |
SU1194273A3 (ru) * | 1981-02-09 | 1985-11-23 | Пфайзер Инк (Фирма) | Способ получени пирбутерола или его аналогов |
GB8414559D0 (en) * | 1984-06-07 | 1984-07-11 | Scras | Pyridine derivatives |
EP0220054A3 (fr) * | 1985-10-16 | 1987-12-02 | Glaxo Group Limited | Dérivés d'éthanolamine |
US4601897A (en) * | 1985-11-06 | 1986-07-22 | Pfizer Inc. | Prazosin-pirbuterol combination for bronchodilation |
AU2270092A (en) * | 1991-06-26 | 1993-01-25 | Sepracor, Inc. | Methods and compositions for treating pulmonary and cardiac disorders using optically pure (-)pirbuterol |
WO1993000090A1 (fr) * | 1991-06-26 | 1993-01-07 | Sepracor, Inc. | Methodes et compositions pour le traitement des troubles pulmonaires et cardiaques avec du pirbuterol optiquement pur (+) |
US7105152B1 (en) | 1991-12-18 | 2006-09-12 | 3M Innovative Properties Company | Suspension aerosol formulations |
US7101534B1 (en) | 1991-12-18 | 2006-09-05 | 3M Innovative Properties Company | Suspension aerosol formulations |
NZ545748A (en) * | 2003-08-29 | 2010-03-26 | Ranbaxy Lab Ltd | Isoxazoline derivatives as inhibitors of phosphodiesterase type-IV |
US20070259874A1 (en) * | 2003-11-26 | 2007-11-08 | Palle Venkata P | Phosphodiesterase Inhibitors |
WO2005092860A1 (fr) * | 2004-03-23 | 2005-10-06 | Pfizer Limited | Composes servant au traitement de maladies |
EP1934219A1 (fr) | 2005-09-16 | 2008-06-25 | Ranbaxy Laboratories Limited | Pyrazolo[3,4-b]pyridines substituees en tant qu'inhibiteurs de la phosphodiesterase |
BRPI0617674A2 (pt) | 2005-10-19 | 2011-08-02 | Ranbaxy Lab Ltd | composições farmacêuticas e seus usos |
WO2007045980A1 (fr) * | 2005-10-19 | 2007-04-26 | Ranbaxy Laboratories Limited | Compositions d'inhibiteurs de la phosphodiesterase de type iv |
CL2007002427A1 (es) * | 2006-08-22 | 2008-03-14 | Ranbaxy Lab Ltd | Compuestos derivados heterociclicos, inhibidores de metaloproteinasa de matriz; proceso de preparacion; composicion farmaceutica, util para el tratamiento o profilaxis de enfermedades inflamatorias o desordenes autoinmunes. |
WO2008035316A2 (fr) * | 2006-09-22 | 2008-03-27 | Ranbaxy Laboratories Limited | Inhibiteurs de phosphodiestérase |
CN101616901A (zh) * | 2006-09-22 | 2009-12-30 | 兰贝克赛实验室有限公司 | Iv型磷酸二酯酶的抑制剂 |
US20080207659A1 (en) * | 2007-02-15 | 2008-08-28 | Asit Kumar Chakraborti | Inhibitors of phosphodiesterase type 4 |
CN101801376A (zh) * | 2007-03-14 | 2010-08-11 | 兰贝克赛实验室有限公司 | 用作磷酸二酯酶抑制剂的吡唑并(3,4-b)吡啶衍生物 |
WO2008111009A1 (fr) * | 2007-03-14 | 2008-09-18 | Ranbaxy Laboratories Limited | Dérivés de pyrazolo[3,4-b]pyridine comme inhibiteurs de phosphodiestérases |
EP2111861A1 (fr) | 2008-04-21 | 2009-10-28 | Ranbaxy Laboratories Limited | Compositions d'inhibiteurs de type IV de la phosphodiestérase |
CA2807097A1 (fr) | 2010-07-30 | 2012-02-02 | Ranbaxy Laboratories Limited | Inhibiteurs de metalloproteinase de matrice |
KR20130140688A (ko) | 2010-09-24 | 2013-12-24 | 랜박시 래보러터리스 리미티드 | 기질 메탈로프로테나제 저해제 |
CN103848781B (zh) * | 2012-11-30 | 2017-06-30 | 重庆华邦制药有限公司 | 高选择性氧化二羟甲基吡啶中一个羟甲基的方法 |
PE20151158A1 (es) | 2012-12-03 | 2015-08-14 | Pfizer | Moduladores selectivos del receptor de androgenos novedosos |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1089189A (en) * | 1964-09-23 | 1967-11-01 | Koninklijke Pharma Fab Nv | Ethers of -(2-pyridyl)benzyl alcohols |
-
1971
- 1971-02-16 US US115878A patent/US3700681A/en not_active Expired - Lifetime
- 1971-11-04 GB GB3749773A patent/GB1367669A/en not_active Expired
- 1971-11-04 GB GB5141671A patent/GB1367668A/en not_active Expired
-
1972
- 1972-01-27 AT AT63972A patent/AT315842B/de not_active IP Right Cessation
- 1972-01-29 DE DE2204195A patent/DE2204195C2/de not_active Expired
- 1972-01-29 DE DE2265581A patent/DE2265581C2/de not_active Expired
- 1972-02-01 BE BE778771A patent/BE778771A/fr not_active IP Right Cessation
- 1972-02-02 FR FR7203470A patent/FR2125309B1/fr not_active Expired
- 1972-02-03 CA CA133,875A patent/CA978962A/en not_active Expired
- 1972-02-04 NL NLAANVRAGE7201471,A patent/NL174349C/xx not_active IP Right Cessation
- 1972-02-04 CH CH164872A patent/CH541560A/fr not_active IP Right Cessation
- 1972-05-25 US US00256641A patent/US3763173A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA978962A (en) | 1975-12-02 |
GB1367668A (en) | 1974-09-18 |
DE2265581C2 (de) | 1982-07-01 |
NL7201471A (fr) | 1972-08-18 |
DE2204195A1 (de) | 1972-08-17 |
NL174349C (nl) | 1984-06-01 |
US3763173A (en) | 1973-10-02 |
FR2125309B1 (fr) | 1976-05-14 |
GB1367669A (en) | 1974-09-18 |
DE2204195C2 (de) | 1981-11-19 |
BE778771A (fr) | 1972-08-01 |
AT315842B (de) | 1974-06-10 |
FR2125309A1 (fr) | 1972-09-29 |
NL174349B (nl) | 1984-01-02 |
US3700681A (en) | 1972-10-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PL | Patent ceased |