CH520671A - Procédé de préparation des 4-Ar3-1(4-Ar-4-Ar2-butyl)-4-hydroxy-pipéridines et produits ainsi obtenus - Google Patents

Procédé de préparation des 4-Ar3-1(4-Ar-4-Ar2-butyl)-4-hydroxy-pipéridines et produits ainsi obtenus

Info

Publication number
CH520671A
CH520671A CH1293670A CH1293670A CH520671A CH 520671 A CH520671 A CH 520671A CH 1293670 A CH1293670 A CH 1293670A CH 1293670 A CH1293670 A CH 1293670A CH 520671 A CH520671 A CH 520671A
Authority
CH
Switzerland
Prior art keywords
piperidines
hydroxy
butyl
products
preparation
Prior art date
Application number
CH1293670A
Other languages
English (en)
Inventor
Frans Hermans Hubert Karel
Josef Niemegeers Carlos Ernest
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of CH520671A publication Critical patent/CH520671A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/35Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction
    • C07C17/354Preparation of halogenated hydrocarbons by reactions not affecting the number of carbon or of halogen atoms in the reaction by hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02Preparation by ring-closure or hydrogenation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40Oxygen atoms
    • C07D211/44Oxygen atoms attached in position 4
    • C07D211/52Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CH1293670A 1969-09-03 1970-08-28 Procédé de préparation des 4-Ar3-1(4-Ar-4-Ar2-butyl)-4-hydroxy-pipéridines et produits ainsi obtenus CH520671A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85501669A 1969-09-03 1969-09-03

Publications (1)

Publication Number Publication Date
CH520671A true CH520671A (fr) 1972-03-31

Family

ID=25320131

Family Applications (1)

Application Number Title Priority Date Filing Date
CH1293670A CH520671A (fr) 1969-09-03 1970-08-28 Procédé de préparation des 4-Ar3-1(4-Ar-4-Ar2-butyl)-4-hydroxy-pipéridines et produits ainsi obtenus

Country Status (22)

Country Link
US (1) US3575990A (fr)
JP (1) JPS4932543B1 (fr)
AT (1) AT299201B (fr)
BE (1) BE755589A (fr)
BR (1) BR6915392D0 (fr)
CH (1) CH520671A (fr)
CS (1) CS159779B2 (fr)
DE (1) DE2040231C3 (fr)
DK (1) DK127424B (fr)
ES (1) ES383006A1 (fr)
FI (1) FI51176C (fr)
FR (1) FR2068536B1 (fr)
GB (1) GB1294733A (fr)
IL (1) IL35211A (fr)
IT (1) IT1040516B (fr)
NL (1) NL172446C (fr)
NO (1) NO131173C (fr)
PL (1) PL71070B1 (fr)
RO (1) RO57021A (fr)
SE (1) SE354066B (fr)
YU (1) YU34354B (fr)
ZA (1) ZA706024B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4129655A (en) * 1976-04-26 1978-12-12 Ciba-Geigy Corporation Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans
US4039676A (en) * 1975-06-23 1977-08-02 Ciba-Geigy Corporation 2-piperidinoalkyl-1,4-benzodioxans
US4383999A (en) * 1981-05-26 1983-05-17 Smithkline Beckman Corporation Inhibition of GABA uptake by N-substituted azaheterocyclic carboxylic acids and their esters
US4514414A (en) * 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
IL90858A (en) * 1988-07-07 1994-08-26 Rhone Poulenc Sante History (Aza) Naftalensultam, their preparation and preparations containing them
DE102004036349A1 (de) * 2004-07-27 2006-03-23 Grünenthal GmbH Substituierte 3-Phenylpiperidin-Derivate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB931788A (en) * 1960-01-14 1963-07-17 Sandoz Ltd Improvements in or relating to benzhydryl esters

Also Published As

Publication number Publication date
IL35211A (en) 1973-11-28
DE2040231B2 (de) 1978-08-10
DE2040231A1 (de) 1971-03-18
YU34354B (en) 1979-07-10
IL35211A0 (en) 1970-11-30
PL71070B1 (fr) 1974-04-30
RO57021A (fr) 1974-12-11
NO131173C (fr) 1975-04-16
AT299201B (de) 1972-06-12
DE2040231C3 (de) 1979-04-12
CS159779B2 (fr) 1975-01-31
ES383006A1 (es) 1973-07-01
GB1294733A (en) 1972-11-01
DK127424B (da) 1973-11-05
NL172446B (nl) 1983-04-05
US3575990A (en) 1971-04-20
FI51176B (fr) 1976-08-02
NL172446C (nl) 1983-09-01
BR6915392D0 (pt) 1973-01-16
FR2068536B1 (fr) 1973-07-13
SE354066B (fr) 1973-02-26
NO131173B (fr) 1975-01-06
JPS4932543B1 (fr) 1974-08-31
BE755589A (fr) 1971-03-02
FR2068536A1 (fr) 1971-08-27
FI51176C (fi) 1976-11-10
ZA706024B (en) 1972-04-26
NL7012199A (fr) 1971-03-05
YU218870A (en) 1978-12-31
IT1040516B (it) 1979-12-20

Similar Documents

Publication Publication Date Title
BE748799A (fr) Procede de preparation de pyrimidinenucleosides et produits obtenus
FR2027367A1 (fr) Procede de preparation de(3-aminopyrazinoyl)-sulfamides et produits obtenus
FR1463438A (fr) Procédé de préparation de nouvelles picolylamines et produits obtenus
CH520671A (fr) Procédé de préparation des 4-Ar3-1(4-Ar-4-Ar2-butyl)-4-hydroxy-pipéridines et produits ainsi obtenus
FR1452911A (fr) Procédé de préparation de dinitrophénols substitués et produits obtenus
FR1202662A (fr) Procédé de préparation des amino-di-thio-thiazoles et produits obtenus
FR1433629A (fr) Procédé de préparation de nu-formyl-alpha-haloacétanilides et nouveaux produits ainsi obtenus
FR1472619A (fr) Procédé de préparation de dérivés de pyridine et nouveaux produits ainsi obtenus
FR1462645A (fr) Procédé de préparation de superpolyesters et nouveaux produits ainsi obtenus
BE746211A (fr) Procede de preparation de 11alpha-hydroxy-3-oxo-delta 1,4- steroides, et produits obtenus
BE726816A (fr) Procédé de préparation de monohydroperoxydes aralcoyliques et produits obtenus
FR1517604A (fr) Procédé de préparation de produits alimentaires contenant de la fécule et produits ainsi obtenus
BE760739A (fr) Procede de preparation de 7-hydroxyalcanals et produits obtenus
BE749487A (fr) Procede de preparation de 2-carbamyl-delta2-imidazolines et produits obtenus
FR1512331A (fr) Procédé de préparation de gamma-lactones substituées et produits en résultant
FR1519520A (fr) Procédé de préparation de dérivés stéroïdes nouveaux et produits ainsi obtenus
FR1477040A (fr) Procédé de préparation d'aminocétones et produits obtenus
FR1489519A (fr) Procédé de préparation de nouveaux 19-nor-stéroïdes et produits obtenus
FR1445034A (fr) Procédé de préparation d'aminoalcanenitriles et nouveaux produits ainsi obtenus
FR1450494A (fr) Procédé de préparation de n-halo-alpha-haloacétanilides et nouveaux produits ainsi obtenus
FR1493989A (fr) Procédé de préparation de dérivés de 7-oxobenzonorbornène et nouvèaux produits ainsi obtenus
FR1518382A (fr) Procédé de préparation de nouvelles benzodiazapines et produits obtenus
FR1447528A (fr) Procédé de préparation de pyridylurées substituées et produits obtenus
FR1540313A (fr) Procédé de préparation de copolymères et produits obtenus
BE755611A (fr) Procede de preparation d'alpha-hydroxylaminolactames et nouveaux produits ainsi obtenus

Legal Events

Date Code Title Description
PL Patent ceased