CH316628A - Process for the preparation of a hydrazone of a heterocyclic aldehyde - Google Patents

Process for the preparation of a hydrazone of a heterocyclic aldehyde

Info

Publication number
CH316628A
CH316628A CH316628DA CH316628A CH 316628 A CH316628 A CH 316628A CH 316628D A CH316628D A CH 316628DA CH 316628 A CH316628 A CH 316628A
Authority
CH
Switzerland
Prior art keywords
hydrazone
preparation
heterocyclic aldehyde
piperonal
aldehyde
Prior art date
Application number
Other languages
German (de)
Inventor
Hans-Albert Dr Offe
Werner Dr Siefken
Domagk Gerhard Prof Dr Dr H C
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of CH316628A publication Critical patent/CH316628A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)

Description

  

  <B>Verfahren</B>     zur   <B>Herstellung eines</B>     Hydrazons   <B>eines</B>     heterocyclischen   <B>Aldehyds</B>    Gegenstand des vorliegenden Patentes ist.  ein Verfahren zur Herstellung eines neuen       Hydrazons    eines     heterocyclischen    Aldehyds,  das dadurch     gekennzeichnet    ist, dass man       Piperonal    mit     Isonikotinsäurehydrazid    um  setzt. Das so erhaltene     Piperonal-isonikotin-          säurehydrazon        schmilzt    bei 236  C. Es soll als  Arzneimittel Verwendung finden.  



  <I>Beispiel</I>  69 Gewichtsteile     Isonikotinsäurehydrazid     werden in 1000     Volumteilen    siedenden Alko  hols gelöst und mit einer Lösung von 75 Ge  wichtsteilen     Piperonal    in 1000     Volumteilen     Alkohol versetzt. Nach kurzem     Erwärmen    kri-         stallisiert    das     Piperonal-isonikotinsäurehydra-          zon,    das nach dem Abkühlen abgesaugt wird.  Ausbeute 120 Gewichtsteile. Nach     Umlösen     aus Methanol zeigt es den F. 236  C.



  <B> Process </B> for <B> producing </B> a </B> hydrazone <B> a </B> heterocyclic <B> aldehyde </B> is the subject of the present patent. a process for the preparation of a new hydrazone of a heterocyclic aldehyde, which is characterized in that piperonal is reacted with isonicotinic acid hydrazide. The piperonal-isonicotinic acid hydrazone thus obtained melts at 236 ° C. It is said to be used as a pharmaceutical.



  <I> Example </I> 69 parts by weight of isonicotinic acid hydrazide are dissolved in 1000 parts by volume of boiling alcohol and a solution of 75 parts by weight of piperonal in 1000 parts by volume of alcohol is added. After a short period of warming, the piperonal-isonicotinic acid hydrazone crystallizes and is filtered off with suction after cooling. Yield 120 parts by weight. After dissolving from methanol it shows the F. 236 C.

Claims (1)

PATENTANSPRUCH Verfahren zur Herstellung eines Hy- drazons eines heterocyclischen Aldehyds, da durch gekennzeichnet, dass man Piperonal mit Isonikotinsäurehydrazid umsetzt. Das so erhaltene Piperonal-isonikotinsäure- hydrazon schmilzt bei 236 C. PATENT CLAIM Process for the production of a hydrazone of a heterocyclic aldehyde, characterized in that piperonal is reacted with isonicotinic acid hydrazide. The piperonal-isonicotinic acid hydrazone thus obtained melts at 236 C.
CH316628D 1951-12-22 1952-11-12 Process for the preparation of a hydrazone of a heterocyclic aldehyde CH316628A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE316628X 1951-12-22
CH313876T 1952-11-12

Publications (1)

Publication Number Publication Date
CH316628A true CH316628A (en) 1956-10-15

Family

ID=25735980

Family Applications (1)

Application Number Title Priority Date Filing Date
CH316628D CH316628A (en) 1951-12-22 1952-11-12 Process for the preparation of a hydrazone of a heterocyclic aldehyde

Country Status (1)

Country Link
CH (1) CH316628A (en)

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