CA3158318A1 - Virtual fiducials - Google Patents

Virtual fiducials

Info

Publication number
CA3158318A1
CA3158318A1 CA3158318A CA3158318A CA3158318A1 CA 3158318 A1 CA3158318 A1 CA 3158318A1 CA 3158318 A CA3158318 A CA 3158318A CA 3158318 A CA3158318 A CA 3158318A CA 3158318 A1 CA3158318 A1 CA 3158318A1
Authority
CA
Canada
Prior art keywords
detector
fiducial
lens
objective lens
microscope
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3158318A
Other languages
English (en)
French (fr)
Inventor
Diping Che
James CHE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequlite Genomics Us Inc
Original Assignee
Che James
Sequlite Genomics Us Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US16/658,052 external-priority patent/US10895727B1/en
Application filed by Che James, Sequlite Genomics Us Inc filed Critical Che James
Publication of CA3158318A1 publication Critical patent/CA3158318A1/en
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/24Base structure
    • G02B21/241Devices for focusing
    • G02B21/245Devices for focusing using auxiliary sources, detectors
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/006Optical details of the image generation focusing arrangements; selection of the plane to be imaged
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0076Optical details of the image generation arrangements using fluorescence or luminescence
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B27/00Optical systems or apparatus not provided for by any of the groups G02B1/00 - G02B26/00, G02B30/00
    • G02B27/32Fiducial marks and measuring scales within the optical system
    • G02B27/34Fiducial marks and measuring scales within the optical system illuminated
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458Fluorescence microscopy

Landscapes

  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
CA3158318A 2019-10-19 2020-10-19 Virtual fiducials Pending CA3158318A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US16/658,052 2019-10-19
US16/658,052 US10895727B1 (en) 2019-10-19 2019-10-19 Microscope for locating structures on the inner surface of a fluidic channel
US202016824632A 2020-03-19 2020-03-19
US16/824,632 2020-03-19
PCT/US2020/056302 WO2021077075A1 (en) 2019-10-19 2020-10-19 Virtual fiducials

Publications (1)

Publication Number Publication Date
CA3158318A1 true CA3158318A1 (en) 2021-04-20

Family

ID=75538690

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3158318A Pending CA3158318A1 (en) 2019-10-19 2020-10-19 Virtual fiducials

Country Status (7)

Country Link
EP (1) EP4031922A4 (zh)
JP (1) JP2022552743A (zh)
KR (1) KR20220084147A (zh)
CN (1) CN114585958B (zh)
AU (1) AU2020366521B2 (zh)
CA (1) CA3158318A1 (zh)
WO (1) WO2021077075A1 (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114280806A (zh) * 2022-02-10 2022-04-05 中国人民解放军陆军装甲兵学院 一种基于相息图的光线准直方法

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JPH09133856A (ja) * 1995-11-07 1997-05-20 Nikon Corp 顕微鏡用自動焦点検出装置
US6025905A (en) * 1996-12-31 2000-02-15 Cognex Corporation System for obtaining a uniform illumination reflectance image during periodic structured illumination
US6181474B1 (en) * 1999-03-22 2001-01-30 Kovex Corporation Scanning confocal microscope with objective lens position tracking
US6974938B1 (en) * 2000-03-08 2005-12-13 Tibotec Bvba Microscope having a stable autofocusing apparatus
JP2002277736A (ja) * 2001-03-21 2002-09-25 Olympus Optical Co Ltd 撮像装置
JP3867143B2 (ja) * 2003-06-25 2007-01-10 独立行政法人産業技術総合研究所 三次元顕微鏡システムおよび画像表示方法
JP2005134834A (ja) * 2003-10-31 2005-05-26 Olympus Corp 撮像装置および電子的撮像機器
US7057826B2 (en) * 2004-03-22 2006-06-06 Angstrom Inc. Small and fast zoom system
US7295303B1 (en) * 2004-03-25 2007-11-13 Kla-Tencor Technologies Corporation Methods and apparatus for inspecting a sample
JP2006047922A (ja) * 2004-08-09 2006-02-16 Nikon Corp 結像装置
JP2006084794A (ja) * 2004-09-16 2006-03-30 Olympus Corp 焦点位置制御機構付き観察装置
US7518726B2 (en) * 2005-04-12 2009-04-14 Caliper Lifesciences, Inc. Compact optical detection system for a microfluidic device
JP5058483B2 (ja) * 2005-09-14 2012-10-24 オリンパス株式会社 生体試料の長期間ないし連続的検出方法
JP2009116271A (ja) * 2007-11-09 2009-05-28 Nikon Corp 焦点調節装置及び顕微鏡装置
US7723657B2 (en) * 2007-11-16 2010-05-25 Mitutoyo Corporation Focus detection apparatus having extended detection range
US9213176B2 (en) * 2008-12-02 2015-12-15 The Regents Of The University Of California Imaging arrangement and microscope
ES2617664T3 (es) * 2009-03-11 2017-06-19 Sakura Finetek U.S.A., Inc. Procedimiento de enfoque automático y dispositivo de enfoque automático
TWI456254B (zh) * 2010-05-19 2014-10-11 Ind Tech Res Inst 螢光顯微影像系統
EP2749941B1 (en) * 2011-08-24 2018-10-10 Olympus Corporation Image capture device and image capture device system
DE102011082756A1 (de) * 2011-09-15 2013-03-21 Leica Microsystems (Schweiz) Ag Autofokussierverfahren und -einrichtung für ein Mikroskop
DE102012009836A1 (de) * 2012-05-16 2013-11-21 Carl Zeiss Microscopy Gmbh Lichtmikroskop und Verfahren zur Bildaufnahme mit einem Lichtmikroskop
CA2878957A1 (en) * 2012-07-25 2014-01-30 Theranos, Inc. Image analysis and measurement of biological samples
CA2905999A1 (en) * 2013-03-15 2014-09-25 The Regents Of The University Of California High-throughput cargo delivery into live cells using photothermal platforms
JP6286183B2 (ja) * 2013-11-07 2018-02-28 株式会社日立ハイテクノロジーズ 分析装置
JP6197880B2 (ja) * 2013-12-12 2017-09-20 株式会社ニコン 構造化照明顕微鏡、構造化照明方法、及びプログラム
US9897791B2 (en) * 2014-10-16 2018-02-20 Illumina, Inc. Optical scanning systems for in situ genetic analysis
US10429628B2 (en) * 2015-04-23 2019-10-01 The University Of British Columbia Multifocal method and apparatus for stabilization of optical systems
DE102015209402A1 (de) * 2015-05-22 2016-11-24 Sirona Dental Systems Gmbh Vorrichtung zur optischen 3D-Vermessung eines Objekts
US10558029B2 (en) * 2016-10-27 2020-02-11 Scopio Labs Ltd. System for image reconstruction using a known pattern
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US10895727B1 (en) * 2019-10-19 2021-01-19 SequLITE Genomics US, Inc. Microscope for locating structures on the inner surface of a fluidic channel

Also Published As

Publication number Publication date
JP2022552743A (ja) 2022-12-19
CN114585958B (zh) 2024-05-28
EP4031922A4 (en) 2022-12-07
EP4031922A1 (en) 2022-07-27
KR20220084147A (ko) 2022-06-21
AU2020366521B2 (en) 2024-03-07
CN114585958A (zh) 2022-06-03
AU2020366521A1 (en) 2022-05-19
WO2021077075A1 (en) 2021-04-22

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