CA2551038C - Derives de triazole utiles comme antagonistes de la vasopressine - Google Patents
Derives de triazole utiles comme antagonistes de la vasopressine Download PDFInfo
- Publication number
- CA2551038C CA2551038C CA2551038A CA2551038A CA2551038C CA 2551038 C CA2551038 C CA 2551038C CA 2551038 A CA2551038 A CA 2551038A CA 2551038 A CA2551038 A CA 2551038A CA 2551038 C CA2551038 C CA 2551038C
- Authority
- CA
- Canada
- Prior art keywords
- phenyl
- compound
- triazol
- mmol
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P15/06—Antiabortive agents; Labour repressants
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- A—HUMAN NECESSITIES
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- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Gynecology & Obstetrics (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Psychology (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0329693.6 | 2003-12-22 | ||
GB0329693A GB0329693D0 (en) | 2003-12-22 | 2003-12-22 | Compounds useful in therapy |
GB0408789.6 | 2004-04-20 | ||
GB0408789A GB0408789D0 (en) | 2004-04-20 | 2004-04-20 | Triazole derivatives |
PCT/IB2004/004059 WO2005063754A1 (fr) | 2003-12-22 | 2004-12-09 | Derives de triazole utiles comme antagonistes de la vasopressine |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2551038A1 CA2551038A1 (fr) | 2005-07-14 |
CA2551038C true CA2551038C (fr) | 2010-04-27 |
Family
ID=34740750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2551038A Expired - Fee Related CA2551038C (fr) | 2003-12-22 | 2004-12-09 | Derives de triazole utiles comme antagonistes de la vasopressine |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1701959A1 (fr) |
JP (1) | JP4698604B2 (fr) |
KR (1) | KR100854872B1 (fr) |
AP (1) | AP2331A (fr) |
AR (1) | AR047340A1 (fr) |
AU (1) | AU2004309164B2 (fr) |
BR (1) | BRPI0417267A (fr) |
CA (1) | CA2551038C (fr) |
CR (1) | CR8481A (fr) |
DO (1) | DOP2004001062A (fr) |
EA (1) | EA010132B1 (fr) |
EC (1) | ECSP066647A (fr) |
GE (1) | GEP20084571B (fr) |
HK (1) | HK1095822A1 (fr) |
IL (1) | IL176349A (fr) |
IS (1) | IS8472A (fr) |
MA (1) | MA28393B1 (fr) |
NL (1) | NL1027833C2 (fr) |
NO (1) | NO20063380L (fr) |
OA (1) | OA13347A (fr) |
PA (1) | PA8620501A1 (fr) |
PE (1) | PE20051051A1 (fr) |
TW (1) | TWI287541B (fr) |
UY (1) | UY28693A1 (fr) |
WO (1) | WO2005063754A1 (fr) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0511504A (pt) | 2004-05-26 | 2008-01-22 | Eisai R&D Man Co Ltd | composto ou um sal farmaceuticamente aceitável do mesmo, e, agente preventivo ou terapêutico para uma doença resultante de beta-amilóides |
CN101083982A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物 |
BRPI0515500A (pt) | 2004-09-20 | 2008-07-29 | Xenon Pharmaceuticals Inc | derivados piridazina para inibição de estearoil-coa-desaturase |
EP1799664A1 (fr) | 2004-09-20 | 2007-06-27 | Xenon Pharmaceuticals Inc. | Derives heterocycliques et leur utilisation en tant qu'inhibiteurs de la stearoyl-coa desaturase |
US7592343B2 (en) | 2004-09-20 | 2009-09-22 | Xenon Pharmaceuticals Inc. | Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors |
BRPI0515488A (pt) | 2004-09-20 | 2008-07-29 | Xenon Pharmaceuticals Inc | derivados de heterocìclicos e seu uso como agentes terapêuticos |
EP2266569A3 (fr) * | 2004-09-20 | 2011-03-09 | Xenon Pharmaceuticals Inc. | Dérivés hétérocycliques et leur utilisation en tant qu'inhibiteurs de la stearoyl-coa desaturase |
AR051091A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
KR20070083781A (ko) | 2004-10-26 | 2007-08-24 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신나미드 화합물의 비정질체 |
AP2007004047A0 (en) | 2005-01-20 | 2007-06-30 | Pfizer Ltd | Substituted triazole derivatives as oxtocin antagonists |
MX2007015216A (es) | 2005-06-03 | 2008-02-22 | Xenon Pharmaceuticals Inc | Derivados de aminotiazol y sus usos como agentes terapeuticos. |
BRPI0614692A2 (pt) * | 2005-07-29 | 2009-05-19 | Hoffmann La Roche | derivados de indol-3-il-carbonil-piperidina e piperazina |
TWI370130B (en) | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
WO2008013622A2 (fr) * | 2006-07-27 | 2008-01-31 | E. I. Du Pont De Nemours And Company | Amides azocycliques fongicides |
US9090604B2 (en) | 2006-07-27 | 2015-07-28 | E I Du Pont De Nemours And Company | Fungicidal azocyclic amides |
AR062095A1 (es) | 2006-07-28 | 2008-10-15 | Eisai R&D Man Co Ltd | Profarmaco de compuesto cinamida |
CA2670671A1 (fr) * | 2006-12-07 | 2008-06-12 | F. Hoffmann-La Roche Ag | Derives de spiro-piperidine |
EP2102207B1 (fr) * | 2006-12-07 | 2010-06-02 | F.Hoffmann-La Roche Ag | Dérivés de spiro-pipéridine |
US7501432B2 (en) * | 2006-12-22 | 2009-03-10 | Hoffman-La Roche Inc. | Spiro-piperidine derivatives |
AU2007341379B2 (en) * | 2006-12-29 | 2012-05-24 | F. Hoffmann-La Roche Ag | Azaspiro derivatives |
CL2008000582A1 (es) | 2007-02-28 | 2008-06-27 | Eisai R&D Man Co Ltd | Compuestos ciclicos derivados de oximorfolina condensados; farmacos que comprenden a dichos compuestos; y su uso para tratar enfermedad de alzheimer, demencia senil, sindrome de down o amiloidosis. |
CA2694401C (fr) | 2007-08-31 | 2012-12-04 | Eisai R&D Management Co., Ltd. | Compose polycyclique |
US7935815B2 (en) | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
EP2358202B1 (fr) * | 2008-11-03 | 2016-06-15 | Merck Sharp & Dohme Corp. | Benzimidazole et aza-benzimidazole carboxamides |
SI2623499T1 (sl) | 2010-10-01 | 2015-10-30 | Taisho Pharmaceutical Co., Ltd. | Derivat 1,2,4-triazolona |
KR102243637B1 (ko) | 2013-03-14 | 2021-04-26 | 리커리엄 아이피 홀딩스, 엘엘씨 | 바이사이클릭 진통 화합물 |
CA2932039A1 (fr) | 2013-12-12 | 2015-06-18 | Kalyra Pharmaceuticals, Inc. | Composes d'alkyle bicyclique et synthese |
CA2942144C (fr) | 2014-03-07 | 2023-08-22 | Kalyra Pharmaceuticals, Inc. | Derives de propellane et synthese |
US10308609B2 (en) | 2014-09-17 | 2019-06-04 | Zeno Royalties & Milestones, LLC | Bicyclic compounds |
EP3197891B1 (fr) | 2014-09-24 | 2018-11-21 | Bayer Pharma Aktiengesellschaft | Dérivés de pyridobenzazépine et de pyridobenzazocine inhibant le facteur xia |
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RU2637101C2 (ru) * | 2016-01-11 | 2017-11-29 | Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр вирусологии и микробиологии" (ФГБНУ ФИЦВиМ) | Устройство для определения аспирированной дозы аэрозолей |
JP2019509338A (ja) * | 2016-02-23 | 2019-04-04 | セルビシオ アンダルーサ デ サルー | 治療活性が増加した抗ウイルス剤としてのピペラジン誘導体 |
WO2017191105A1 (fr) | 2016-05-03 | 2017-11-09 | Bayer Pharma Aktiengesellschaft | Dérivés d'aryltriazole à substitution amide et leurs utilisations |
WO2017191114A1 (fr) | 2016-05-03 | 2017-11-09 | Bayer Aktiengesellschaft | Dérivés d'hétéroaryltriazole substitués par hydroxyalkyle et utilisations associées |
US10525041B2 (en) | 2016-05-03 | 2020-01-07 | Bayer Pharma Aktiengesellschaft | Fluoroalkyl-substituted aryltriazole derivatives and uses thereof |
US9988367B2 (en) * | 2016-05-03 | 2018-06-05 | Bayer Pharma Aktiengesellschaft | Amide-substituted pyridinyltriazole derivatives and uses thereof |
US10800746B2 (en) | 2016-05-03 | 2020-10-13 | Bayer Pharma Aktiengesellschaft | Oxoalkyl-substituted phenyltriazole derivatives and uses thereof |
AR108265A1 (es) | 2016-05-03 | 2018-08-01 | Bayer Pharma AG | Derivados de feniltriazol sustituidos con amida y usos de estos |
JP6710273B2 (ja) * | 2016-05-09 | 2020-06-17 | 日本曹達株式会社 | 環状アミン化合物および有害生物防除剤 |
US10927098B2 (en) | 2016-10-20 | 2021-02-23 | Bayer Pharma Aktiengesellschaft | Hydroxyalkyl-substituted triazole derivatives and uses thereof |
KR20200018440A (ko) | 2017-05-15 | 2020-02-19 | 리커리엄 아이피 홀딩스, 엘엘씨 | 진통제 화합물 |
CA3084421A1 (fr) | 2017-10-24 | 2019-05-02 | Bayer Pharma Aktiengesellschaft | Derives de triazole substitues et utilisations associees |
EP3700897A1 (fr) | 2017-10-24 | 2020-09-02 | Bayer Pharma Aktiengesellschaft | Dérivés de triazole substitués et utilisations associées |
US11331314B2 (en) | 2017-10-24 | 2022-05-17 | Bayer Pharma Aktiengesellschaft | Amine substituted triazole derivatives and uses thereof |
JP2021500365A (ja) | 2017-10-24 | 2021-01-07 | バイエル・アクチエンゲゼルシヤフト | 置換トリアゾール誘導体のプロドラッグ及びその使用 |
WO2019081306A1 (fr) | 2017-10-24 | 2019-05-02 | Bayer Pharma Aktiengesellschaft | Dérivés de triazole substitués et utilisations associées |
EP3700900A1 (fr) | 2017-10-24 | 2020-09-02 | Bayer Aktiengesellschaft | Dérivés de triazole substitués et utilisations associées |
WO2019081291A1 (fr) | 2017-10-24 | 2019-05-02 | Bayer Aktiengesellschaft | Promédicaments de dérivés de triazole substitués, et utilisations de ceux-ci |
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US4481360A (en) * | 1983-08-26 | 1984-11-06 | The Upjohn Company | 4H-1,2,4-Triazol-3-yl compounds |
WO2001058880A1 (fr) * | 2000-02-08 | 2001-08-16 | Yamanouchi Pharmaceutical Co., Ltd. | Derives de triazole |
EP1293503A4 (fr) * | 2000-05-19 | 2008-04-02 | Astellas Pharma Inc | Derives de triazole |
-
2004
- 2004-12-09 EP EP04801354A patent/EP1701959A1/fr not_active Withdrawn
- 2004-12-09 OA OA1200600206A patent/OA13347A/en unknown
- 2004-12-09 KR KR1020067012328A patent/KR100854872B1/ko not_active IP Right Cessation
- 2004-12-09 AU AU2004309164A patent/AU2004309164B2/en not_active Ceased
- 2004-12-09 GE GEAP20049469A patent/GEP20084571B/en unknown
- 2004-12-09 WO PCT/IB2004/004059 patent/WO2005063754A1/fr active Application Filing
- 2004-12-09 AP AP2006003631A patent/AP2331A/xx active
- 2004-12-09 BR BRPI0417267-1A patent/BRPI0417267A/pt active Search and Examination
- 2004-12-09 JP JP2006546356A patent/JP4698604B2/ja not_active Expired - Fee Related
- 2004-12-09 CA CA2551038A patent/CA2551038C/fr not_active Expired - Fee Related
- 2004-12-09 EA EA200600925A patent/EA010132B1/ru not_active IP Right Cessation
- 2004-12-17 TW TW093139507A patent/TWI287541B/zh active
- 2004-12-21 NL NL1027833A patent/NL1027833C2/nl not_active IP Right Cessation
- 2004-12-21 AR ARP040104826A patent/AR047340A1/es not_active Application Discontinuation
- 2004-12-21 UY UY28693A patent/UY28693A1/es unknown
- 2004-12-22 PA PA20048620501A patent/PA8620501A1/es unknown
- 2004-12-22 DO DO2004001062A patent/DOP2004001062A/es unknown
-
2005
- 2005-01-03 PE PE2005000032A patent/PE20051051A1/es not_active Application Discontinuation
-
2006
- 2006-05-18 IS IS8472A patent/IS8472A/is unknown
- 2006-06-15 EC EC2006006647A patent/ECSP066647A/es unknown
- 2006-06-15 IL IL176349A patent/IL176349A/en not_active IP Right Cessation
- 2006-06-22 CR CR8481A patent/CR8481A/es not_active Application Discontinuation
- 2006-06-22 MA MA29125A patent/MA28393B1/fr unknown
- 2006-07-21 NO NO20063380A patent/NO20063380L/no not_active Application Discontinuation
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2007
- 2007-03-20 HK HK07102965.0A patent/HK1095822A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
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EA010132B1 (ru) | 2008-06-30 |
AU2004309164B2 (en) | 2007-11-15 |
NL1027833C2 (nl) | 2006-03-06 |
IL176349A0 (en) | 2006-10-05 |
WO2005063754A1 (fr) | 2005-07-14 |
EA200600925A1 (ru) | 2006-12-29 |
HK1095822A1 (en) | 2007-07-06 |
AR047340A1 (es) | 2006-01-18 |
MA28393B1 (fr) | 2007-01-02 |
CR8481A (es) | 2007-12-04 |
IS8472A (is) | 2006-05-18 |
ECSP066647A (es) | 2006-10-25 |
TWI287541B (en) | 2007-10-01 |
DOP2004001062A (es) | 2005-06-30 |
AP2331A (en) | 2011-12-05 |
NL1027833A1 (nl) | 2005-06-23 |
UY28693A1 (es) | 2005-07-29 |
NO20063380L (no) | 2006-09-22 |
KR20060101546A (ko) | 2006-09-25 |
JP4698604B2 (ja) | 2011-06-08 |
OA13347A (en) | 2007-04-13 |
IL176349A (en) | 2011-11-30 |
BRPI0417267A (pt) | 2007-04-17 |
AU2004309164A1 (en) | 2005-07-14 |
KR100854872B1 (ko) | 2008-08-28 |
AP2006003631A0 (en) | 2006-06-30 |
EP1701959A1 (fr) | 2006-09-20 |
PA8620501A1 (es) | 2005-08-04 |
TW200528099A (en) | 2005-09-01 |
JP2007515468A (ja) | 2007-06-14 |
CA2551038A1 (fr) | 2005-07-14 |
GEP20084571B (en) | 2008-12-25 |
PE20051051A1 (es) | 2005-12-17 |
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