CA2416456A1 - Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides - Google Patents
Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides Download PDFInfo
- Publication number
- CA2416456A1 CA2416456A1 CA002416456A CA2416456A CA2416456A1 CA 2416456 A1 CA2416456 A1 CA 2416456A1 CA 002416456 A CA002416456 A CA 002416456A CA 2416456 A CA2416456 A CA 2416456A CA 2416456 A1 CA2416456 A1 CA 2416456A1
- Authority
- CA
- Canada
- Prior art keywords
- seq
- acid sequence
- amino acid
- pro
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Cette invention se rapporte à de nouveaux polypeptides et à des molécules d'acide nucléique codant ces polypeptides. Cette invention concerne également des vecteurs et des cellules hôtes comprenant ces séquences d'acide nucléique, des molécules de polypeptide chimérique comprenant ces polypeptides fusionnés à des séquences de polypeptides hétérologues, des anticorps qui se fixent à ces polypeptides et des procédés destinés à produire ces polypeptides.
Applications Claiming Priority (52)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21955600P | 2000-07-20 | 2000-07-20 | |
US60/219,556 | 2000-07-20 | ||
US22066400P | 2000-07-25 | 2000-07-25 | |
US22063800P | 2000-07-25 | 2000-07-25 | |
US22066600P | 2000-07-25 | 2000-07-25 | |
US22060700P | 2000-07-25 | 2000-07-25 | |
US22062400P | 2000-07-25 | 2000-07-25 | |
US22058500P | 2000-07-25 | 2000-07-25 | |
US22060500P | 2000-07-25 | 2000-07-25 | |
US60/220,666 | 2000-07-25 | ||
US60/220,585 | 2000-07-25 | ||
US60/220,664 | 2000-07-25 | ||
US60/220,638 | 2000-07-25 | ||
US60/220,607 | 2000-07-25 | ||
US60/220,605 | 2000-07-25 | ||
US60/220,624 | 2000-07-25 | ||
US22089300P | 2000-07-26 | 2000-07-26 | |
US60/220,893 | 2000-07-26 | ||
PCT/US2000/020710 WO2001009327A2 (fr) | 1999-07-28 | 2000-07-28 | Procede de prevention de la deterioration ou de la mort des cellules de la retine et de traitement des troubles oculaires |
USPCT/US00/20710 | 2000-07-28 | ||
US22242500P | 2000-08-01 | 2000-08-01 | |
US60/222,425 | 2000-08-01 | ||
US22713300P | 2000-08-22 | 2000-08-22 | |
US60/227,133 | 2000-08-22 | ||
USPCT/US00/23522 | 2000-08-23 | ||
PCT/US2000/023522 WO2001016319A2 (fr) | 1999-08-31 | 2000-08-23 | Compositions et procedes pour le traitement de maladies d'ordre immunologique |
PCT/US2000/023328 WO2001016318A2 (fr) | 1999-09-01 | 2000-08-24 | Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci |
USPCT/US00/23328 | 2000-08-24 | ||
US60/000,000 | 2000-09-15 | ||
PCT/US2000/030873 WO2001040465A2 (fr) | 1999-11-30 | 2000-11-10 | Compositions et procedes de traitement de maladies d'ordre immunologique |
USPCT/US00/30873 | 2000-11-10 | ||
US25364600P | 2000-11-28 | 2000-11-28 | |
US60/253,646 | 2000-11-28 | ||
USPCT/US00/32678 | 2000-12-01 | ||
PCT/US2000/032678 WO2001040466A2 (fr) | 1999-12-01 | 2000-12-01 | Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides |
US09/747,259 | 2000-12-20 | ||
US09/747,259 US6569645B2 (en) | 1999-05-14 | 2000-12-20 | IL-17 homologous polypeptides and therapeutic uses thereof |
PCT/US2000/034956 WO2001046420A2 (fr) | 1999-12-23 | 2000-12-20 | Polypeptides homologues de l'il-17 et leurs utilisations therapeutiques |
USPCT/US00/34956 | 2000-12-20 | ||
PCT/US2001/006520 WO2001068848A2 (fr) | 2000-03-01 | 2001-02-28 | Polypeptides secretes et transmembranaires et acides nucleiques codant pour ces polypeptides |
USPCT/US01/06520 | 2001-02-28 | ||
USPCT/US01/06666 | 2001-03-01 | ||
PCT/US2001/006666 WO2001066740A2 (fr) | 2000-03-03 | 2001-03-01 | Compositions et methodes de traitement de maladies d'origine immune |
US09/816,744 US6579520B2 (en) | 1998-05-15 | 2001-03-22 | IL-17 related mammalian cytokine polypeptides (IL-17E) |
US09/816,744 | 2001-03-22 | ||
US09/854,208 US7217412B2 (en) | 1998-05-15 | 2001-05-10 | IL-17C related mammalian cytokine polypeptides |
US09/854,280 | 2001-05-10 | ||
US09/854,208 | 2001-05-10 | ||
US09/854,280 US7115398B2 (en) | 1998-05-15 | 2001-05-10 | IL-17 homologous polypeptides and therapeutic uses thereof |
USPCT/US01/17092 | 2001-05-25 | ||
PCT/US2001/017092 WO2001092331A2 (fr) | 2000-05-30 | 2001-05-25 | Compositions et methodes de traitement de maladies d'origine immune |
PCT/US2001/021066 WO2002008288A2 (fr) | 2000-07-20 | 2001-06-29 | Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2416456A1 true CA2416456A1 (fr) | 2002-01-31 |
Family
ID=56290161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002416456A Abandoned CA2416456A1 (fr) | 2000-07-20 | 2001-06-29 | Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1354040A2 (fr) |
JP (1) | JP2004514420A (fr) |
AU (2) | AU2001273150A1 (fr) |
CA (1) | CA2416456A1 (fr) |
WO (1) | WO2002008288A2 (fr) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU738688B2 (en) | 1997-09-12 | 2001-09-27 | Apoxis Sa | Cysteine rich receptors-train |
US7771719B1 (en) | 2000-01-11 | 2010-08-10 | Genentech, Inc. | Pharmaceutical compositions, kits, and therapeutic uses of antagonist antibodies to IL-17E |
US20020106728A1 (en) * | 2000-06-20 | 2002-08-08 | Genentech, Inc. | NS4 nucleic acids and polypeptides and methods of use for the treatment of body weight disorders |
US20030232056A1 (en) | 1999-09-10 | 2003-12-18 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
EP1897945B1 (fr) * | 1999-12-23 | 2012-01-18 | Genentech, Inc. | Polypeptides allogéniques IL-17 et utilisations thérapeutiques |
AU6531101A (en) * | 2000-06-02 | 2001-12-17 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US20030096969A1 (en) | 2000-06-02 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP1700867A3 (fr) * | 2000-06-02 | 2006-09-20 | Genentech, Inc. | Polypeptide secrétée et transmembranaire, ainsi que les acides nucléiques qui les codent |
US20030096339A1 (en) | 2000-06-26 | 2003-05-22 | Sprecher Cindy A. | Cytokine receptor zcytor17 |
US20030017572A1 (en) * | 2000-09-25 | 2003-01-23 | Rajasekhar Bandaru | 56294 and 56629, novel human metalloproteases and uses thereof |
EP1325029A2 (fr) * | 2000-09-28 | 2003-07-09 | Eli Lilly And Company | Nouvelles proteines secretees et utilisations de ces dernieres |
AU2002230778A1 (en) | 2000-11-03 | 2002-05-15 | The Regents Of The University Of California | Prokineticin polypeptides, related compositions and methods |
AU2002226079A1 (en) | 2000-12-08 | 2002-06-18 | Curagen Corporation | Method of detecting and treating tuberous sclerosis complex associated disorders |
DE10106835A1 (de) * | 2001-02-14 | 2002-09-05 | Basf Lynx Bioscience Ag | Signaltransduktionsproteine 15B3, 15B3-1 und 15B3-2 und zugrundeliegende DNA-Sequenzen |
GB2378183A (en) * | 2001-04-25 | 2003-02-05 | Smithkline Beecham Corp | Assays of the interaction between AXOR8 or AXOR52 and BV-8 ligand |
CA2446610A1 (fr) * | 2001-06-06 | 2002-12-12 | Human Genome Sciences, Inc. | 20 proteines humaines secretees |
US20030120040A1 (en) | 2001-06-29 | 2003-06-26 | Genentech, Inc. | Secreted and Transmembrane polypeptides and nucleic acids encoding the same |
SI2230299T1 (sl) | 2002-01-18 | 2012-07-31 | Zymogenetics Inc | Nov citokinski zcytor ligand |
MXPA04010092A (es) * | 2002-04-16 | 2004-12-13 | Genentech Inc | Composiciones y metodos para el diagnostico y tratamiento de tumores. |
US7141381B2 (en) | 2002-04-25 | 2006-11-28 | Bristol-Myers Squibb Company | Human leucine-rich repeat-containing proteins specifically expressed in the nervous system |
EP1416279B1 (fr) * | 2002-10-31 | 2008-12-31 | F. Hoffmann-La Roche Ag | Methodes et compositions pour le diagnostic du cancer du pancreas |
DE10254601A1 (de) * | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
EP1573048A4 (fr) * | 2002-12-20 | 2007-02-14 | Avalon Pharmaceuticals | Proteine specifique du sein exprimee dans le cancer, et ses methodes d'utilisation |
EP2526960A1 (fr) | 2003-03-12 | 2012-11-28 | Genentech, Inc. | Utilisation de BV8 et/ou de EG-VEGF pour promouvoir l'hématopoièse |
EP1617802A4 (fr) * | 2003-04-30 | 2007-08-01 | Centocor Inc | Polynucleotides specifiques de cngh0010, polypeptides, anticorps, compositions, methodes et utilisations |
US7479479B2 (en) | 2003-04-30 | 2009-01-20 | Centocor, Inc. | CNGH0010 specific polynucleotides, polypeptides, antibodies, compositions, methods and uses |
EP1503212B1 (fr) * | 2003-07-28 | 2007-05-23 | F. Hoffmann-La Roche Ag | Méthode de diagnostic de métastases, thérapie et composition utile à cela |
US20100031378A1 (en) | 2008-08-04 | 2010-02-04 | Edwards Joel A | Novel gene disruptions, compositions and methods relating thereto |
US20070259383A1 (en) * | 2004-03-02 | 2007-11-08 | Eisal R&D Management Co., Ltd | Novel Genes involved in Epidermal differentiation, and uses thereof |
CA2572239C (fr) | 2004-06-24 | 2019-07-09 | Mayo Foundation For Medical Education And Research | Polypeptide costimulant b7-h5 |
JP2008505182A (ja) | 2004-07-02 | 2008-02-21 | ジェネンテック・インコーポレーテッド | 非ホジキンリンパ腫の治療のための組成物と方法 |
US7846438B2 (en) | 2004-08-03 | 2010-12-07 | Biogen Idec Ma Inc. | Methods of promoting neurite outgrowth with soluble TAJ polypeptides |
US8101183B2 (en) | 2005-05-06 | 2012-01-24 | Zymogentics, Inc. | Variable region sequences of IL-31 monoclonal antibodies |
JP5065253B2 (ja) | 2005-05-06 | 2012-10-31 | ザイモジェネティクス, インコーポレイテッド | Il−31モノクローナル抗体とその使用法 |
AU2007254715B2 (en) | 2005-05-06 | 2013-08-29 | Zymogenetics, Inc. | Methods of treating pain and inflammation in neuronal tissue using IL-31 antagonists |
US20130216542A1 (en) | 2005-05-06 | 2013-08-22 | Zymogenetics, Inc. | Variable region sequences of il-31 monoclonal antibodies and methods of use |
JP2007063225A (ja) | 2005-09-01 | 2007-03-15 | Takeda Chem Ind Ltd | イミダゾピリジン化合物 |
US8034822B2 (en) | 2006-03-08 | 2011-10-11 | Takeda San Diego, Inc. | Glucokinase activators |
EP2049518B1 (fr) | 2006-05-31 | 2011-08-31 | Takeda San Diego, Inc. | Derives de l'indazole et de l'isoindazole comme agents de l'activation de glucokinase |
EP2091947A2 (fr) | 2006-12-20 | 2009-08-26 | Takeda San Diego, Inc. | Activateurs de glucokinase |
US8173645B2 (en) | 2007-03-21 | 2012-05-08 | Takeda San Diego, Inc. | Glucokinase activators |
ME03057B (fr) | 2007-12-07 | 2019-01-20 | Zymogenetics Inc | Molécules d'anticorps humanisés spécifiques pour l'IL-31 |
KR20110025649A (ko) | 2008-05-05 | 2011-03-10 | 노비뮨 에스 에이 | 항-il-17a/il-17f 교차-반응성 항체 및 그의 사용 방법 |
US9809815B2 (en) | 2009-02-20 | 2017-11-07 | Ganymed Pharmaceuticals Ag | Methods and compositions for diagnosis and treatment of cancer |
RU2605318C2 (ru) | 2009-05-05 | 2016-12-20 | Новиммун С.А. | Анти-il-17f антитела и способы их применения |
CA2775373C (fr) | 2009-11-11 | 2019-10-29 | Ganymed Pharmaceuticals Ag | Anticorps specifiques pour la claudine 6 (cldn6) |
EP2404936A1 (fr) | 2010-07-06 | 2012-01-11 | Ganymed Pharmaceuticals AG | Thérapie du cancer utilisant des anticorps in vivo dirigés sur la cible CLDN6 |
CN107090043B (zh) | 2011-05-13 | 2021-12-07 | 加尼梅德药物公司 | 用于治疗表达密蛋白6之癌症的抗体 |
US9848543B2 (en) | 2013-07-09 | 2017-12-26 | E I Du Pont De Nemours And Company | System and method for irrigation |
WO2015014376A1 (fr) | 2013-07-31 | 2015-02-05 | Biontech Ag | Diagnostic et thérapie du cancer impliquant des cellules souches cancéreuses |
GB201810301D0 (en) * | 2018-06-22 | 2018-08-08 | Evox Therapeutics Ltd | Combinatorial gene therapy |
CN111848792B (zh) * | 2020-07-16 | 2023-02-24 | 浙江省食品药品检验研究院 | 疫苗中牛血清白蛋白等杂质的抗体制备方法及检测方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5536637A (en) * | 1993-04-07 | 1996-07-16 | Genetics Institute, Inc. | Method of screening for cDNA encoding novel secreted mammalian proteins in yeast |
US6060249A (en) * | 1997-02-27 | 2000-05-09 | Genentech, Inc. | Method of selection for genes encoding secreted and transmembrane proteins |
AU3753499A (en) * | 1998-04-20 | 1999-11-08 | Paul B. Fisher | Colon cancer-associated antigens and their diagnostic and therapeutic uses |
EP1263948A2 (fr) * | 1999-03-08 | 2002-12-11 | Genentech, Inc. | Polypeptides secretes et transmembranaires et acides nucleiques codant pour ces polypeptides |
CA2361277A1 (fr) * | 1999-03-12 | 2000-09-21 | Craig A. Rosen | Proteines humaines secretees (49) |
EP1208195A2 (fr) * | 1999-06-15 | 2002-05-29 | Genentech Inc. | Polypeptides secretes et transmembranaires et acides nucleiques codant pour ceux-ci |
WO2001055355A1 (fr) * | 2000-01-31 | 2001-08-02 | Human Genome Sciences, Inc. | Acides nucleiques, proteines et anticorps |
AU6531101A (en) * | 2000-06-02 | 2001-12-17 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
-
2001
- 2001-06-29 WO PCT/US2001/021066 patent/WO2002008288A2/fr active Search and Examination
- 2001-06-29 JP JP2002514192A patent/JP2004514420A/ja active Pending
- 2001-06-29 EP EP01952391A patent/EP1354040A2/fr not_active Withdrawn
- 2001-06-29 CA CA002416456A patent/CA2416456A1/fr not_active Abandoned
- 2001-06-29 AU AU2001273150A patent/AU2001273150A1/en not_active Abandoned
- 2001-07-02 AU AU7315001A patent/AU7315001A/xx active Pending
Also Published As
Publication number | Publication date |
---|---|
EP1354040A2 (fr) | 2003-10-22 |
AU7315001A (en) | 2002-01-30 |
WO2002008288A3 (fr) | 2003-08-14 |
AU2001273150A1 (en) | 2002-02-05 |
WO2002008288A2 (fr) | 2002-01-31 |
JP2004514420A (ja) | 2004-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
FZDE | Discontinued |