CA2371604A1 - Integrin receptor antagonists - Google Patents

Integrin receptor antagonists Download PDF

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CA2371604A1
CA2371604A1 CA002371604A CA2371604A CA2371604A1 CA 2371604 A1 CA2371604 A1 CA 2371604A1 CA 002371604 A CA002371604 A CA 002371604A CA 2371604 A CA2371604 A CA 2371604A CA 2371604 A1 CA2371604 A1 CA 2371604A1
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gly
bala
bhs
phhs
tolhs
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French (fr)
Inventor
Andreas Kling
Udo Lange
Arnulf Lauterbach
Herve Geneste
Thomas Subkowski
Johann-Christian Zechel
Claudia Isabella Graef
Wilfried Hornberger
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Abbott GmbH and Co KG
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Priority claimed from DE1999119218 external-priority patent/DE19919218A1/en
Priority claimed from DE1999148269 external-priority patent/DE19948269A1/en
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Publication of CA2371604A1 publication Critical patent/CA2371604A1/en
Abandoned legal-status Critical Current

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Abstract

The invention relates to new compounds which bind to integrin receptors, as well as to their production, their use as integrin receptor antagonists and for the treatment of diseases, pharmaceutical preparations containing said compounds and pharmaceutical preparations containing at least one other acti ve compound.

Description

DEMANDES OU BREVETS VOLUMINEUX
LA PRESENTE PARTIE I)E CETTE DEMANDE OU CE BREVETS
COMPRI~:ND PLUS D'UN TOME.
CECI EST ~.E TOME 1 DE 2 NOTE: Pour les tomes additionels, veillez contacter 1e Bureau Canadien des Brevets.
JUMBO APPLICATIONS / PATENTS
THIS SECTION OF THE APPLICATION / PATENT CONTAINS MORE
THAN ONE VOLUME.

NOTE: For additional vohxmes please contact the Canadian Patent Oi~ice.

Integrin receptor antagonists The invention relates to novel compounds which bind to integrin receptors, their preparation and use.
Integrins are cell surface glycoprotein receptors which mediate interactions between cells of the same type and different cells, and between cells and extracellular matrix proteins. They are involved in physiological processes such as, for example, embryogenesis, hemostasis, wound healing, immune response and formation) maintenance of the tissue architecture.
Disturbances of the expression of cell adhesion molecule genes, and disturbances of receptor function may contribute to the pathogenesis of a large number of disorders such as, for example, tumors, thromboembolic events, cardiovascular disorders, pulmonary diseases, disorders of the CNS, of the kidney, of the gastrointestinal tract or inflammations.
Integrins are heterodimers each consisting of an a and a (3 transmembrane subunit which are connected noncovalently. To date, 16 different a and 8 different (3 subunits and 22 different combinations have been identified.
Integrin a~(33, also called vitronectin receptor, mediates adhesion to a large number of ligands - plasma proteins, extracellular matrix proteins, cell surface proteins - most of which contain the aminoacid sequence RGD (Cell, 1986, 44, 517-518; Science 1987, 238, 491-497), such as, for example, vitronectin, fibrinogen, fibronectin, von Willebrand factor, thrombospondin, osteopontin, laminin, collagen, thrombin, tenascin, MMP-2, bone sialoprotein II, various viral, parasitic and bacterial proteins, natural integrin antagonists such as disintegrins, neurotoxins - mambin - and leech proteins - decorsin, ornatin - and same non-RGD ligands such as, for example, Cyr-61, PECAM (L. Piali, J. Cell Biol. 1995, 130, 451-460; Buckley, J. Cell Science 1996, 109, 437-445, J. Biol. Chem. 1998, 273, 3090-3096).
Several integrin receptors show cross-reactivity with ligands which contain the RGD motif.
Thus, integrin anb(33, also called platelet fibrinogen receptor, recognizes fibronectin, vitronectin, thrombospondin, von Willebrand factor and fibrinogen.
Integrin aV(33 is expressed inter alia on endothelial cells, blood platelets, monocyteslmacrophages, smooth muscle cells, some B cells, fibroblasts, osteoclasts and various tumor cells such as, for example, melanomas, glioblastomas, carcinomas of the lung, breast, prostate and bladder, osteosarcomas or neuroblastomas.

_2_ Increased expression is observed under various pathological conditions, such as, for example, in the prothrombotic state, in cases of vessel injury, tumor growth or metastasis or reperfusion and on activated cells, in particular on endothelial cells, smooth muscle cells or macrophages.
Involvement of integrin a"~i3 has been detected inter alia in the following pathological states:
cardiovascular disorders such as atherosclerosis, restenosis after vessel injury, and angioplasty (neointima formation, smooth muscle cell migration and proliferation) (J. Vasc.
Surg. 1994, 19, 125-134; Circulation 1994, 90, 2203-2206), acute kidney failure (Kidney Int. 1994, 46, 1050-1058; Proc. Natl. Acad. Sci.
1993, 90, 5700-5704; Kidney Int. 1995, 48, 1375-1385), angiogenesis-associated microangiopathies such as, for example, diabetic retinopathy or rheumatoid arthritis (Ann. Rev. Physiol 1987, 49, 453-464; Int. Ophthalmol.
1987, 11, 41-50;
Cell 1994, 79, 1157-1164; J. Biol. Chem. 1992, 267, 10931-10934), arterial thrombosis, stroke (phase II studies with ReoPro, Centocor Inc., 8'" annual European Stroke Meeting), cancers such as, for example, in tumor metastasis or tumor growth (tumor-induced angiogenesis) (Cell 1991, 64, 327-336; Nature 1989, 339, 58-61; Science 1995, 270, 1500 1502), osteoporosis (bone resorption after proliferation, chemotaxis and adhesion of osteoclasts to bone matrix) (FASEB J. 1993, 7, 1475-1482; Exp. Cell Res. 1991, 195, 368-375, Cell 1991, 64, 327-336), high blood pressure, psoriasis, hyperparathyroidism, Paget's disease, malignant hypercalcemia, metastatic osteolytic lesions, inflammation, heart failure, CHF, and for antiviral, antiparasitic or antibacterial therapy and prophylaxis (adhesion and internalization).
Because of its key role, pharmaceutical preparations which contain low molecular weight WO 00!66618 PCTIEP00103469 integrin a~,a3 antagonists are of great therapeutic and diagnostic use inter alia for the said indications.
Advantageous a"~i3 integrin receptor antagonists bind to the integrin a~(33 receptor with increased affinity.
Particularly advantageous a"(33 integrin receptor antagonists additionally have increased selectivity for integrin av(33 and have less effect on integrin am(33 by a factor of at least 10, preferably by a factor of at least 100.
An integrin a"~i3 antagonist effect has been shown, and a beneficial in vivo effect has been demonstrated, for a large number of compounds such as anti-a"(33 monoclonal antibodies, peptides containing the RGD binding sequence, natural RGD-containing proteins (for example disintegrins) and low molecular weight compounds (FEBS Letts 1991, 291, 50-54;
J. Biol. Chem. 1990, 265, 12267-12271; J. Biol. Chem. 1994, 269, 20233-20238;
J. Cell Biol 1993, 51, 206-218; J. Biol. Chem. 1987, 262, 17703-17711; Bioorg. Med. Chem.
1998, 6, 1185-1208).
WO 9708145 describes meta-guanidine, urea, thiourea or azacyclic aminobenzoic acid derivatives and their use as av(33 integrin receptor antagonists.
It is an object of the present invention to provide novel integrin receptor antagonists with advantageous properties.
We have found that this object is achieved by compounds of the formula I
A-E-G-L
where A, E, G and L have the following meanings:
L a structural element of the formula I~
~a R2 ~~T zL
Rj where a is0or1, T is a COOH group or a radical which can be hydrolyzed to COOH, RZ is hydrogen, NHS02Rz', NHCORz' orNHCO0R22, where Rz' is a branched or unbranched, optionally substituted C~-Cs-alkyl, C3-C6-cycloalkyl, C~-C4-alkyl-C3-C6-cycloalkyl radical, CS-C,2-bicycloalkyl or C6-C~e-tricycloalkyl radical, an up to trisubstituted, with identical or different radicals, aryl, alkylaryl, hetarylalkyl radical or 3- to 6-membered, saturated, unsaturated or aromatic heterocycle which may contain up to three different or identical heteroatoms O, N, S, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and this ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, RZZ is a branched or unbranched, optionally substituted C~-Cg-alkyl radical or an optionally substituted aryl or alkylaryl radical, R3 is hydrogen or -(CH2)b-(X)~-R3', where b is 0, 1, 2 or 3, c is0or1, X is -SOZ-, -S-, -O-, -CO-, -NH-SOZ-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R3')-, -N(Rs,)-CO-, -SOZ-NH-, -SOZ-N(Rs,)- or-N(R3')-S02-, R3' is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted C~_C~-alkyl, C~-C4-alkoxy, -O-alkylaryl or -O-aryl radical, an amino radical with primary or optionally secondary or tertiary substitution, an optionally C~_C4-alkyl- or aryl-substituted CZ-C6-alkynyl or C2-C6-alkenyl radical, a C5-C~2-bicycloalkyl, C6-C~$-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3-C8-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, and R4 is hydrogen, or a branched or unbranched, optionally substituted C~-4-alkyl, C3-C6-alkenyl, C3-C6-alkynyl or C3-C6-cycloalkyl radical, G a structural element of the formula I~
where Rb JN IG
)d R
d is 0, 1 or 2, R5 is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted C,-Cs-alkyl, C~-C4-alkoxy, -O-alkylaryl or -O-aryl radical, an amino radical with primary or optionally secondary or tertiary substitution, an optionally C~-C4-alkyl- or aryl-substituted CZ-C6-alkynyl or C2-C6-alkenyl radical, a C5-C~2-bicycloalkyl, C6-C~8-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3-CS-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, or the side chain of a natural amino acid, R6 is hydrogen or a branched or unbranched, optionally substituted C,-C4-alkyl, C3-C6-alkenyl, C3-C6-alkynyl or C3-C6-cycloalkyl radical, E a structural element of the formula IE
-(NH)s (CHZ)~Q-(CH2)e-CO- I
where a is 0, 1 or 2, f is0or1, g is0orl, Q is a doubly linked, optionally substituted hetaryl radical, it being possible for finro substituents together to be a saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and this ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, A one of the structural elements of the formulae IAi to IAZo _7_ Rls Rls R16 R17 'N TA2 R17 N _ ~~~3 ''' \~/
N N
W
Rl ~. ~ IAa 10 ~ IA5 la Q IA( 1 R ~N IA7 R ~N~
Rll Rll ~N IA9 Z= Z~~ N
CN' ' N~ I
R15 R15 Z2' Z1 A15 N~.-- ~N
~ is Ris R Rls N IA~.a ~~C IA15 ~ IAis H' C~N
p N
~ls H
w ZAm N IAie N ~A19 I~2a I
I I
H
where R'°, R" are, independently of one another, hydrogen, -(CH2),,-(Y);-R'°', or the two radicals together are a 3- to 8-membered, optionally substituted, saturated, unsaturated or aromatic N-heterocycle which may additionally contain two other, identical or different heteroatoms O, N or S, where h is 0, 1, 2 or 3, WO 00!66618 PCTlEP00103469 _g_ is0or1, Y is -SOZ-, -S-, -O-, -CO-, -NH-S02-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R~°~)-, -N(R'°')-CO-, -SOZ-NH-, -N(R'°')-SOZ- or -SOZ-N(R'°')- and R'°' is a hydroxyl group, a branched or unbranched, optionally substituted C1-C6-alkyl, C~-C4-alkoxy, -O-alkylaryl or -O-aryl radical, an amino radical with primary or optionally secondary or tertiary substitution, an optionally C~-C4-alkyl- or aryl-substituted Cz-C6-alkynyl or CZ-Cs-alkenyl radical, a C5-C~2-bicycloalkyl, C6-C18-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3~-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms 0, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, R'2 is a branched or unbranched, optionally substituted C1-C4-alkyl, alkylaryl, C3-C6-cycloalkyl or C~-C4-alkyl-C3-C6-cycloalkyl radical or an optionally substituted aryl radical, R'3 is hydrogen, -OH, -CN, -CONH2, a branched or unbranched, optionally substituted Ci-C4-alkyl, C~-C4-alkoxy or -OCO-C,-C4-alkyl radical, or an optionally substituted alkylaryl, -O-alkylaryl, -OCO-aryl, -OCO-alkylaryl or -OCO-ally!
radical, R'4 is hydrogen, a branched or unbranched, optionally substituted C~-C4-alkyl, alkyl aryl, -COZ-C~-C4-alkyl, -C02-alkylaryl, -COZ-ally!, -CO-C,-Cø-alkyl, -CO-alkylaryl or -CO-ally! radical, R'S is hydrogen, a branched or unbranched, optionally substituted C~-C4-alkyl radical or an optionally substituted aryl or alkylaryl radical.
R'6, R" are, independently of one another, -NH2, halogen or a branched or unbranched, optionally substituted C1-C4-alkyl or C,-C4-alkoxy radical or an optionally substituted aryl radical, WO 00!66618 PCTIEP00I03469 -g_ Z', Z2, Z3, Z4 are, independently of one another, CH, C-CH3, C-OCH3, C-CI or N
and the physiologically tolerated salts, prodrugs and the enantiomerically pure or diastereomerically pure and tautomeric forms.
T in the structural element L means a COOH group or a radical which can be hydrolyzed to COOH. A radical which can be hydrolyzed to COOH means a radical which is converted into a COOH group after hydrolysis.
A group which may be mentioned as an example of a radical T which can be hydrolyzed to COOH is O
_~C_R1 in which R' has the following meaning:
a) OM, where M can be a metal ration such as an alkali metal ration such as lithium, sodium, potassium, the equivalent of an alkaline earth metal ration such as calcium, magnesium and barium, or an environmentally compatible organic ammonium ion such as tertiary C~-C4-alkylammonium or an ammonium ion, such as, for example, ONa, OK or OLi, b) a branched or unbranched, optionally halogen-substituted C~-Ce-alkoxy radical such as, for example, methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy, 1,1-dimethylethoxy, in particular methoxy, ethoxy, 1-methylethoxy, pentoxy, hexoxy, heptoxy, octoxy, difluoromethoxy, trifluoromethoxy, chlorodifluoro-methoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 1,1,2,2-tetrafluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-1,1,2-trifluoroethoxy or pentafluoroethoxy c) a branched or unbranched, optionally halogen-substituted C~-C4-alkylthio radical such as methylthio, ethylthio, propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio or 1,1-dimethylethylthio radical d) an optionally substituted -O-alkylaryl radical such as, for example, -O-benzyl e) R' also a radical of the formula -(O)m-N(R'e)(R'9), in which m is 0 or 1, and R'e and R'9, which may be identical or different, have the following meaning:
hydrogen, C,-C8-alkyl, such as, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methyl-propyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 1,2-dimethylpropyl, 1,1-dimethylpropyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, methylpentyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,3-dimethylbutyl, 1,1-dimethylbutyl, 2,2-dimethylbutyl, 3,3-dimethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethylbutyl, 2-ethylbutyl, heptyl or octyl, C3-C6-alkenyl such as, for example, 2-propenyl, 2-butenyl, 3-butenyl, 1-methyl-propenyl, 2-methyl-2-propenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1,1-dimethyl-2-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-2-propenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3 butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3 dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 1-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl 2-butenyl, 2-ethyl-3-butenyl, 1,1,2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl and 1-ethyl-2-methyl-2-propenyl, in particular 2-propenyl, 2-butenyl, 3-methyl-2-butenyl and 3-methyl-2-pentenyl, C3-C6-alkynyl such as, for example, 2-propynyl, 2-butynyl, 3-butynyl, 1-methyl-propynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 1-methyl-2-butynyl, 1,1-dimethyl-2-propynyl, 1-ethyl-2-propynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, 1-methyl-2-pentynyl, 1-methyl-3-pentynyl, 1 methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-4-pentynyl, 4 methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1,1-dimethyl-3-butynyl, 1,2-dimethyl-3 butynyl, 2,2-dimethyl-3-butynyl, 1-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl and 1-ethyl-1-methyl-2-propynyl, preferably 2-propynyl, 2-butynyl, 1-methyl-2-propynyl and 1-methyl-2-butynyl, in particular 2-propynyl, C3-C8-cycfoalkyl, such as, for example, cyclopropyl, cyclobutyl, cyclopenfyl, cyclohexyl -11 _ and cycloheptyl, cyclooctyl, it being possible for these alkyl, cycloalkyl, alkenyl and alkynyl groups each to be substituted, phenyl, optionally substituted one or more times, for example one to three times, by halogen, nitro, cyano, C~-C4-alkyl, C1-C4-haloalkyl, C~-C4-alkoxy, C~-C4-haloalkoxy or C~-C4-alkylthio, such as, for example, 2-fluorophenyl, 3-chlorophenyl, 4-bromophenyl, 2-methylphenyl, 3-nitrophenyl, 4-cyanophenyl, 2-trifluoromethylphenyl, 3-methoxy-phenyl, 4-trifluoroethoxyphenyl, 2-methylthiophenyl, 2,4-dichlorophenyl, 2-methoxy-3-methylphenyl, 2,4-dimethoxyphenyl, 2-vitro-5-cyanophenyl, 2,6-difluorophenyl or R'$ and R'9 together form a C4-C~-alkylene chain which is closed to a ring, is optionally substituted, for example by C~-C4-alkyl and may contain a heteroatom selected from the group of oxygen, sulfur or nitrogen, such as, for example, -(CHZ)a-, -(CHz)s-~ -(CH2)s-, -(CHz)r~ -(CHZ)2-O-(CHz)2-, -CH2-S-(CH2)3-. -(CHz)z-O-(CHZ)3-~ -NH-(CH2)3-, -CHz-NH-(CHZ)2-, -CH2-CH=CH-CH2-, -CH=CH-(CH2)3-, -CO-(CHZ)2-CO- or -CO-(CHz)3-CO-.
Preferred T radicals are -COOH, -CO-O-C~-Cs-alkyl or -CO-O-benryl.
A branched or unbranched C~-Cs-alkyl radical for R2' in the structural element L means, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 1,2-dimethylpropyl, 1,1-dimethylpropyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1-methylpentyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,3-dimethylbutyl, 1,1-dimethylbutyl, 2,2-dimethylbutyl, 3,3-dimethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethylbutyl, 2-ethylbutyl or 1-ethyl-2-methylpropyl, preferably methyl, ethyl, propyl, butyl or i-butyl.
A branched or unbranched C3-Cs-cycloalkyl radical for RZ' in the structural element L means, for example, cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl.
A branched or unbranched C~-C4-alkyl-C3-Cs-cycloalkyl radical for R2' in structural element L
means an abovementioned C3-Cs-cycloalkyl radical which is a substituent on a C~-C4-alkyl radical.
The C~-Cs-alkyl radicals, C3-Cs-cycloalkyl radicals or C~-C4-alkyl-C3-Cs-cycloalkyl radical may be substituted by up to 5 identical or different radicals selected from the group of halogen, aryl or hetaryl.

WO 00166618 PCTlEP00103469 A C5-C,Z-bicycloalkyl radical for Rz' means, for example, indanyl, norbornyl or camphyl, and a C6-C,$-tricycloalkyl radical means, for example, adamantyl.
An up to trisubstituted, with identical or different radicals, aryl, alkylaryl, alkylhetaryl radical or 3- to 6-membered, saturated, unsaturated or aromatic heterocycle which may contain up to three different or identical heteroatoms O, N, S, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms 0, N, S, and for the ring to optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring to be fused to this ring for R2' in structural element L means, for example, aryl radicals such as, for example, phenyl, 1-naphthyl or 2-naphthyl, alkylaryl radicals such as, for example, benzyl or phenethyl, alkylhetaryl radicals such as, for example, -CHZ-2-pyridyl, -CHz-3-pyridyl, -CH2-4-pyridyl, -CH2-2-thienyl, -CHr3-thienyl, -CHZ-2-thiazolyl, -CH2-4-thiazolyl, CH2-5-thiazolyl, -CHZ-CHZ-2-pyridyl, -CH2-CH2-3-pyridyl, -CH2-CHZ-4-pyridyl, -CHz-CHZ-2-thienyl, -CH2-CH2-3-thienyl, -CHZ-CHZ-2-thiazolyl, -CHz-CHZ-4.-thiazolyl, or -CH2-CH2-5-thiazolyl, preferably -CHZ-2-pyridyl, -CH2-2-thienyl, or-CHz-2-thiazolyl or hetaryl radicals such as, for example, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl, 3-furyl, 2-pyrrolyl, 3-pyrrolyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl, 5-thiazofyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 2-pyrimidyl, 4-pyrimidyl, 5-pyrimidyl, 6-pyrimidyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 2-imidazolyl, 4-imidazolyl, 5-imidazolyl, 3-pyridazinyl, 4-pyridazinyl, 5-pyridazinyl or 6-pyridazinyl, preferably 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl or 5-thiazolyl, it being possible for the aryl radicals, alkylaryl radicals, alkylhetaryl radicals and hetaryl radicals to be substituted by up to three identical or different radicals, for example selected from the following group:
-N02, -NHZ, -OH, -CN, -COOH, -COO-C,-C4-alkyl, halogen, a branched or unbranched, optionally substituted C,-C4-alkyl, C3-C6-cycloalkyl, C,-C4-alkoxy, C,-C4-alkylthio, -O-CH2-COO-C,-C4-alkyl, -NH-CO-C,-C4-alkyl, -CO-NH-C~-C4-alkyl, -NH-SOz-C,-C4-alkyl, -SOz-NH-C,-C4-alkyl, -N(C,-C4-alkyl)2, -NH-C,-C4-alkyl, or -SOZ-C,-C4-alkyl radical, an optionally WO 00/66618 PCTIEP00l03469 substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-S02-phenyl, -S02-NH-phenyl, -NH-CO-benzyl, -CO-NH-benryl, -NH-SOZ-benryl, -S02-NH-benryl, an optionally substituted radical -S02-NT'Tz or -CO-NT'Tz where the two radicals T' and Tz may form a cyclic amine, or a 3-to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, or two radicals together are a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms 0, N, S, and the ring can optionally be substituted or another, optionally substituted ring can be fused to this ring.
Preferred substituents on the aryl radicals, alkylaryl radicals, alkylhetaryl radicals and hetaryl radicals for RZ' are C~-C4-alkyl, C3-C6-cycloalkyl, -COOH, -COOMe, -CF3, -CN, C~-C4-alkoxy, -SCH3, -O-CHz-COOH, phenyl, -SOZCH3, -NO2, -OH, -NHz, -N-pyrrolidinyl, -N-piperidinyl, -N-morpholinyl, -N-piperazinyl, -NH-C~-C4-alkyl, -N(C~-C4-alkyl)z, F, CI, Br or I.
Preferred substituents on the aryl radicals, alkylaryl radicals, alkylhetaryl radicals and hetaryl radicals for RZ' in which two radicals together are a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms 0, N, S, and the ring can optionally be substituted or another optionally substituted ring can be fused to this ring, are the following doubly linked structural elements:
.>; O . /
>:
. O ,:'~o ~ ' H
.~~~S ~-N
,'~...~NS ~/ ~/ '/
A branched or unbranched C~-C~-alkyl radical for R22 in structural element L
means, for example, the C~-C6-alkyl radicals mentioned above for Rz', preferably 1,1-dimethylethyl.
Examples of aryl radicals for R~ in structural element L are phenyl, 1-naphthyl or 2-naphthyl, preferably phenyl; alkylaryl radicals for R22 in structural element L are preferably benzyl or phenethyl.
Suitable substituents on the C~-C6-alkyl radical, aryl radicals or alkylaryl radicals for R2z in structural element L are the substituents mentioned above for the aryl radicals, the alkylaryl radicals, alkylhetaryl radicals and hetaryl radicals of RZ'.

In the radical R3 in structural element L, the index b can be 0, 1, 2 or 3, preferably 0, 1 or 2, and the index c can be 0 or 1. The radical X is a doubly linked radical selected from the group of -S02-, -S-, -O-, -CO-, -NH-S02-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R3')-, -N(R3')-CO-, -SOZ-NH-, -SOZ-N(R3')- or -N(R3')-SOZ-. In the case of radicals which are disubstituted by R3', the two R3' radicals can be identical or different.
A branched or unbranched C~-C6-alkyl radical for R3' in structural element L
means, for example, methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-di-methylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 1,2~limethylpropyl, 1,1-dimethylpropyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1-methylpentyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,3-dimethylbutyl, 1,1-dimethylbutyl, 2,2-dimethylbutyl, 3,3-dimethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethylbutyl, 2-ethylbutyl or 1-ethyl-2-methylpropyl, preferably methyl, ethyl, propyl, butyl, iso-propyl, sec-butyl and tert-butyl.
A branched or unbranched C~-C4-alkoxy radical for R3' in structural element L
means, for example, methoxy, ethoxy, propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy or 1,1-dimethylethoxy, in particular methoxy, ethoxy or 1-methylethoxy.
Examples of -O-alkylaryl or -O-aryl radicals are -O-phenyl, -O-1-naphthyl, -O-2-naphthyl or -O-benzyl.
The C,-C6-alkyl, C,-C4-alkoxy radicals of R3' in structural element L can be substituted by up to five identical or different radicals selected from the group of halogen, aryl or hetaryl.
Substituted -O-alkylaryl or -O-aryl radicals mean, for example, the abovementioned -O-alkyl-aryl or -O-aryl radicals, it being possible for the aryl moiety to be substituted by up to three identical or different radicals selected from the following group:
-NO2, -NHz, -OH, -CN, -COOH, -C00-C~-C4-alkyl, halogen, a branched or unbranched, optionally substituted C,-C4-alkyl, C3-C6-cycloalkyl, C~-C4-alkoxy, C,-C4-alkylthio, -0-CHz-COO-C~-C4-alkyl, -NH-CO-C~-C4-alkyl, -CO-NH-C~-C4-alkyl, -NH-SOz-C~-C4-alkyl, -SOZ-NH-C,-C4-alkyl, -N(Ci-C4-alkyl)2, -NH-C~-C4-alkyl, or -SOZ-C~-C4-alkyl radical, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-SOZ-phenyl, -SOZ-NH-phenyl, -NH-CO-benzyl, -CO-NH-benzyl, -NH-S02-benzyl, -SOz-NH-benzyl, an optionally substituted radical -SOz-NT'T2 or -CO-NT'TZ where the two radicals T' and T2 may form a cyclic amine, or a 3-to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms 0, N, S, or two radicals together are a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted or another, optionally substituted ring can be fused to this ring.
An amino radical with primary or optionally secondary or tertiary substitution for R3' in structural element L means a primary amino radical -NH2, a secondary amino radical -NH(R3") or a tertiary amino radical -N(R3")(Ral2), where R3" and R3'2 can be, independently of one another, C~-C4-alkyl or C3-C6-cycloalkyl as mentioned above, optionally substituted aryl, preferably phenyl, alkylaryl, preferably benzyl, -CO-C~-C4-alkyl, preferably -CO-CH3 or -CO-aryl, preferably -CO-phenyl.
In the case where c = 1 and X = CO, the corresponding amide residues result.
Cyclic tertiary amide residues or amino radicals result in the case where R3' is one of the heterocyclic systems described below, which is linked via the ring nitrogen to X = CO or directly. Examples of preferred amide residues -X-R3' are 0 0 _ N N ~ VO
A C2-Cs-alkynyl or C2-C6-alkenyl radical which is optionally substituted by C,-C4-alkyl or aryl for R3' in the structural element L means, for example, CZ-Cs-alkynyl radicals such as, for example, ethynyl, 2-propynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 1-methyl-2-butynyl, 1,1-dimethyl-2-propynyl, 1~thyl-2-propynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, 1-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-4-pentynyl, 4-methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1,1-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 1-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl or 1-ethyl-1-methyl-2-propynyl, preferably 2-propynyl or ethynyl or C2-Cs-alkenyl radical such as, for example, vinyl, 2-propenyl, 2-butenyl, 3-butenyl, 1-methyl-2-propenyl, 2-methyl-2-propenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-Methyl-3-butenyl, 3-methyl-3-butenyl, 1,1-dimethyl-2-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-2-propenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 1-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1,1,2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl or 1-ethyl-2-methyl-2-propenyl, in particular 2-propenyl or vinyl which can be substituted by optionally substituted Ci-C4-alkyl radicals, or aryl radicals as mentioned above, preferably phenyl, such as, preferably, phenylethynyl or phenylethenyl.
A C~-C~2-bicycloalkyl radical for R3' means, for example, indanyl, norbornyl or camphyl, and a C6-C,B-tricycloalkyl radical means, for example, adamantyl.
A 3-to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3-C8-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and for the ring to optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring to be fused to this ring, for R3' in structural element L means, for example 3- to 6-membered, saturated or unsaturated heterocycles which may contain up to three different or identical heteroatoms O, N, S, such as N-pyrrolidinyl, N-piperidinyl, N-hexahydroazepinyl, N-morpholinyl or N-piperazinyl, it being possible for free amine protons in heterocycles with free amine protons, such as, for example, N-piperazinyl, to be replaced by conventional amine protective groups such as, for example, methyl, benzyl, Boc (tert-butoxycarbonyl), Z (benzyloxycarbonyl), tosyl, -S02-C~-C4-alkyl, -SOZ-phenyl or -S02-benzyl, C3-C8-cycloalkyl radicals as described above for Rz', aryl radicals such as, for example, phenyl, 1-naphthyl or 2-naphthyl or hetaryl radicals such as, for example, 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl, 3-furyl, 2-pyrrolyl, 3-pyrrolyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl, 5-thiazolyl, 2-oxazolyl, 4-oxazolyl, 5-oxazofyl, 2-pyrimidyl, 4-pyrimidyl, 5-pyrimidyl, 6-pyrimidyl, 3-pyrazolyl, 4-pyrazolyl, 5-pyrazolyl, 3-isothiazolyl, 4-isothiazolyl, 5-isothiazolyl, 2-imidazolyl, 4-imidazolyl, 5-imidazolyl, 3-pyridazinyl, 4-pyridazinyl, 5-pyridazinyl or 6-pyridazinyl, preferably 2-pyridyl, 3-pyridyl, 4-pyridyl, 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-thiazolyl, 4-thiazolyl or 5-thiazolyl, it being possible for the heterocyclic, C3-C8-cycloalkyl, aryl and hetaryl radicals optionally to be substituted by up to three identical or different radicals, for example selected from the following group:
-NOz, -NH2, -OH, -CN, -COOH, -COO-C~-C4-alkyl, halogen, a branched or unbranched, optionally substituted C~-C4-alkyl, C3-C6-cycloalkyl, G~-C4-alkoxy, C~-C4-alkylthio, -O-CHZ-COO-C~-C4-alkyl, -NH-CO-Ci-C4-alkyl, -CO-NH-C~-C4-alkyl, -NH-S02-C,-C4-alkyl, -SOZ-NH-C~-C4-alkyl, -N(C~-C4-alkyl)2, -NH-C~-C4-alkyl, or -SOZ-C~-C4-alkyl radical, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-SOrphenyl, -SOZ-NH-phenyl, -NH-CO-benzyl, -CO-NH-benzyl, -NH-S02-benzyl, -S02-NH-benzyl, an optionally substituted radical -SOz-NT'Tz or -CO-NT'TZ where the two radicals T' and T2 may form a cyclic amine, or a 3-to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, or two radicals together are a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted or another, optionally substituted ring can be fused to this ring.
Preferred substituents of the heterocyclic, C3-C$-cycloalkyl, aryl and hetaryl radicals for R3' are C~-C4-alkyl, -COOH, -COOMe, -CF3, -CN, Ci-C4-alkoxy, -SCH3, -O-CH2-COOH, -phenyl, -SOzCH3, -N02, -OH, -NHz, -N-pyrrolidinyl-, -N-piperidinyl, -N-morpholinyl, -N-piperazinyl, -NH-C~-C4-alkyl, -N(C~-C4-alkyl)Z, F, CI, Br or I.
Preferred substituents of the heterocyclic, C3-C8-cycloalkyl, aryl and hetaryl radicals for R3' in which two radicals together are a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted ring can be fused to this ring, are the following, doubly linked structural elements:
, . r ~ , , ° %'o ; ~.
H
~S .YN
. S ,r ;~ ;..
.~~'" N

WO 00!66618 PCTJEPOOJ03469 Examples of the resulting condensed ring systems for R3' are, for example, the corresponding dioxolanyls, benzopyrrolyls, benzofuryls, benzothienyls or fluorenyls, A branched or unbranched, optionally substituted C~-C4-alkyl radical for R4 in structural element L means, for example, methyl, ethyl, propyl, i-propyl, butyl, t-butyl or i-butyl, preferably methyl.
A branched or unbranched, optionally substituted C3-C6-cycloalkyl radical for R4 in structural element L means the radicals mentioned above for Rz', which are optionally substituted by up to 5 radicals such as halogen or aryl, preferably cyclohexyl, cyclopentyl or cyclopropyl.
C3-C~-alkenyl or C3-C6-alkynyl radicals for R4 in structural element L are the radicals mentioned above for R'8 or R'9, preferably ally! or propargyl.
Particularly preferred radicals for R4 are hydrogen, methyl, cyclopropyl, ally! or propargyl, and hydrogen is very particularly preferred.
Preferred structural elements L have a = 1, so that a (3-amino acid represents the preferred basic structure of the structural element L. In particularly preferred structural elements L, either the radical R2 = hydrogen and the radical R3 may vary widely as described above, or the radical R3 = hydrogen and the radical RZ may vary widely as described above. Very particularly preferred structural elements L have R2 = H and R3 may vary widely as described above, or R3 = H and RZ = -NHZ, -NH-SOZ-phenyl or -NH-SOZ-benzyl, where Z is the benzyloxycarbonyl protective group.
In structural element G of the formula I~, RS means hydrogen and, independently of R3' in structural element L, the same radicals as described above for R3' or another side chain of a natural amino acid. Preferred R5 radicals are hydrogen, methyl, ethynyl or methyl-substituted ethynyl, and hydrogen is particularly preferred.
Rs means, independently of R4, the same radicals as described above for R4.
Preferred Rs radicals are hydrogen, methyl, ally!, propargyl or cyclopropyl, and hydrogen is particularly preferred.
In structural element E of the formula IE, Q means a doubly linked hetaryl radical which is optionally substituted by up to three other radicals, it being possible where appropriate for two radicals together to be a saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring.
A hetaryl radical preferably means a 5- or 6-membered aromatic heterocyclic system which may contain up to three different or identical heteroatoms O, N, S, it being possible for the free amine protons in heterocycles with free amine protons, such as, for example, imidazolyl, triazolyl, pyrazolyl or pyrrolyl, to be replaced by conventional amine protective groups such as, for example, methyl, benryl, Boc (tent-butoxycarbonyl), Z
(benzyloxycarbonyl), tosyl, -S02-C~-Ca-alkyl, -SOz-phenyl or -S02-benzyl.
Preferred hetaryl radicals Q which may be listed are the following structures where the points of linkage are indicated by a bond line:
N.
S
N-N ~ ~
N 11 ~~ %r '1 S ~N ~O. ~'~ /C,N,.
H H
~~- ~~~
N N N S
Particularly preferred hetaryl radicals Q which may be listed are the following structures where the fixed positions of the points of linkage are indicated by a bond line, and the structures can be incorporated in both orientations:

WO 00!66618 PCTIEP00l03469 I ! /
0 N~ 0 H
N_~ ~N N I~ l~ N N
O ~S~ ~S, ~Q
H
'W. ~ N ~ N
( i ( i ~ ~ ~ l1~ f' N N N N
H H
Very particularly preferred hetaryl radicals Q which may be listed are the following structures where the fixed positions of the points of linkage are indicated by a bond line, and the structures can be incorporated in both orientations:
S S O O H N
~,~~
~ 'E'S'N x As mentioned above, the free amine protons of imidazolyl, pyrazolyl, triazolyl or pyrrolyl in these preferred and particularly preferred structures can also be replaced by conventional amine protective groups such as, for example, methyl, benzyl, Boc (tert-butoxycarbonyl), Z
(benzyloxycarbonyl), tosyl, -S02-C,-Ca-alkyl, -S02-phenyl or -SOZ-benzyl, Preferred substitutents of the hetaryl radicals are, independently of one another, one or two radicals selected from the group of -CN, halogen, preferably CI or F, C~-C4-alkyl, preferably methyl, C~-C4-haloalkyl, preferably trifluoromethyl, C,-Ca-alkoxy, preferably methoxy, -NH-C,-C4-alkyl or aryl, preferably phenyl.
The structural element A is one of the structural elements of the formula IA'to IA2o Rls Rie Ris R17 / IA1 Rl7 ~ n2 R17 " \ IA3 N N
0 Ri ' S
R1 ~, ~ IA4 R'- \N I, ZA5 R1 ~ p Rii ~N IAs ~N IA9 Z/~a N IAlo rt-~ N
Rls Ris ZZ\Zi Nls R
N~ /All ( ~~A12 ~A13 N
N N
Ri s Ri 5 N
Ris O
N xAl4 H3C N IA15 ~ ~ zAl6 O' _N
Rls H
N jAl7 N IA18 _N Inl9 In20 O~N
x where the structural elements of the formula IA', IA2, IA3, IA~, IAS, IAe, IA'°, or ~,q'3 are preferred, and the structural element of the formula IA4 A

is particularly preferred, for the structural element A.

The radicals R'° and R" are, independently of one another and independently of R3, the radicals described above for R3 in structural element L, preferably C~-C4-alkyl, C3-C8-cyclo-alkyl, C,-Ca-alkyl-C3-Ce-cycloalkyl, aryl, alkylaryl, hetaryl or alkylhetaryl, it being possible for the aryl, alkylaryl, hetaryl and alkylhetaryl radicals to carry up to three identical or different radicals of the group F, CI, Br or I, C~-C4-alkyl, C3-C6-cycloalkyl, -COOH, -COOMe, -CF3, -CN, Ci-C4-alkoxy, -SCH3, -O-CHZ-COOH, phenyl, -S02CH3, -N02, -OH, -NH2, -N-pyrrolidinyl, -N-piperidinyl, -N-morpholinyl, -N-piperazinyl, -NH-C~-C4-alkyl, -N(C~-C4-alkyl)z, -NH-CO-C~-C4-alkyl, -CO-NH-C,-C4-alkyl, -NH-SOZ-C~-C4-alkyl, -SOZ-NH-C~-C4-alkyl, or -S02-C~-C4-alkyl, optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-SOZ-phenyl, -SOz-NH-phenyl, -NH-CO-benzyl, -CO-NH-benzyl, -NH-SO2-benzyl, -SOZ-NH-benzyl, optionally substituted -SOz-NT'T2 or -CO-NT'T2, where the two radicals T' and T~ may form a cyclic amine, or the two radicals R'° and R" together a 3- to 8-membered, optionally substituted, saturated, unsaturated or aromatic N-heterocyclic system which may additionally contain two other identical or different heteroatoms O, N, or S, such as, for example, pyrrolidinyl, piperidinyl, hexahydroazepinyl, piperazinyl or morpholinyl.
R'2 is a branched or unbranched, optionally substituted C~-C4-alkyl, alkylaryl, C3-C6-cycloalkyl or C~-C4-alkyl-C3-C6-cycloalkyl radical or an optionally substituted aryl radical as described above for Rz'.
A branched or unbranched, optionally substituted C~-C4-alkoxy or -O-alkylaryl radical for R'3 means the corresponding radicals as described above for R3', preferably methoxy or benzyloxy. The radicals -OCO-C,-C4-alkyl-, -OCO-aryl-, -OCO-alkylaryl- or -OCO-allyl- are comprised of the group -OCO- and the C~-C4-alkyl, aryl or alkylaryl radicals described above under R3', or the allyl radical.
Preferred R'3 radicals are hydrogen, -OH, -O-benzyl, -OCO-phenyl, -OCO-benzyl, -OCO-allyl, -CN or-CO-NH2.
Analogously, the radicals -C02-C~~-alkyl-, -COz-alkylaryl-, -COz-allyl-, -CO-C,-C4-alkyl-, -CO
alkylaryl- or -CO-allyl for the radical R'4 are composed of the group -C02- or -CO- and the C~-C4-alkyl, aryl radical described above under R3' or the allyl radical.
Preferred radicals for R'4 are hydrogen, methyl, benzyl, -COO-benzyl, -COO-allyl, -CO-benzyl or -CO-allyl.
R'S is hydrogen, a branched or unbranched, optionally substituted C~-C4-alkyl radical or an WO 00!66618 PCTIEP00103469 optionally substituted aryl or alkylaryl radical as described above for R~' or R4. Preferred R'S
radicals are hydrogen, methyl, benzyl or phenyl.
R's, R" are, independently of one another, -NH2, halogen, such as CI, Br, I or F or a branched or unbranched, optionally substituted C~-C4-alkyl or C,-C4-alkoxy or optionally substituted aryl radical as described above for R3', preferably NH2, CI, F, methyl, methoxy or phenyl.
Z', Z2, Z3, Z4 are, independently of one another, CH, C-CH3, C-OCH3, C-CI or N, it being preferred that Z' and Z2 or ZZ and Z3 or Z3 and Z4 are not simultaneously N.
Unless specified in detail, substituted aryl, alkylaryl, hetaryl or alkylhetaryl radicals in the description mean aryl, alkylaryl, hetaryl or alkylhetaryl radicals which may be substituted by up to three identical or different radicals selected from the following group:
-NO2, -NHz, -OH, -CN, -COOH, -O-CH2-COOH, -COO-C1-C4-alkyl, halogen, a branched or unbranched, optionally substituted C~-C4-alkyl, C3-Cs-cycloalkyl, C~-C4-alkoxy, C~-C4-alkyl-thio, -O-CH2-COO-C~-C4-alkyl, -NH-CO-Ci-C4-alkyl, -CO-NH-C~-C4-alkyl, -NH-SOZ-C,-C4-alkyl, -S02-NH-C~-Ca-alkyl, -N(Ci-C4-alkyl)z, -NH-C~-C4-alkyl, or -SOz-Ci-C4-alkyl radical, an optionally substituted -NH-CO-phenyl, -CO-NH-phenyl, -NH-SOZ-phenyl, -S02-NH-phenyl, -NH-CO-benzyl, -CO-NH-benzyl, -NH-S02-benzyl, -S02-NH-benzyl, an optionally substituted radical -S02-NT'T2 or -CO-NT'TZ where the two radicals T' and T2 may form a cyclic amine, or a 3- to 6-membered, optionally substituted, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, or two radicals together are a fused, saturated, unsaturated or aromatic carbocycle or hetero-cycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted or another, optionally substituted ring can be fused to this ring.
The compounds of the formula I and also the intermediates for their preparation may have one or more asymmetric substituted carbon atoms. The compounds may be in the form of pure enantiomers or pure diastereomers or mixture thereof. It is preferred to use an enantiomerically pure compound as active ingredient.
The compounds of the formula I may also be in the form of physiologically tolerated salts.
The compounds of the formula I may also be in a prodrug form in which the compounds of the formula I are liberated under physiological conditions. Reference may be made herd for example to the group T in structural element L, which in some cases contains groups which can be hydrolyzed under physiological conditions to the free carboxyl group.
Derivatized structural elements A which liberate the structural element A under physiological conditions are also suitable.
In a preferred embodiment of the compounds of the formula I, the indices a, e, f and g and the heterocycle Q are chosen so that the distance between the group T and the structural element A is from 10 to 14 atomic linkages, preferably 11 to 13 atomic linkages, along the shortest possible route along the molecule backbone.
Further preferred compounds of the formula I have the preferred structural elements A of the formula IA', IqZ, Ip3, Iq°, IgS, IqB, IA'° or IA'3 whsle the structural elements E, G and L may vary widely as described above.
Further preferred compounds of the formula I have the particularly preferred structural element A of the formula Iq4, while the structural elements E, G and L may vary widely as described above.
Particularly preferred compounds of the formula I have the preferred structural elements A of the formula Iq', Iq~, Iq3, Iq°, IqS, IAe, IA'° or Iq'3 and the preferred region of the structural element L, while the structural elements E and G may vary widely as described above.
Further particularly preferred compounds of the formula I have the particularly preferred structural element A of the formula Iq4 and the preferred region of the structural element L, while the structural elements E and G may vary widely as described above.
Further particularly preferred compounds of the formula I have the preferred structural element A of the formula Iq4 and the preferred region of the structural element E, while the structural elements L and G may vary widely as described above.
Very particularly preferred compounds of the formula I have the preferred structural element A of the formula Iq4, the preferred region of the structural element E and the preferred region of the structural element L, while the structural element G may vary widely as described above.
Further very particularly preferred compounds of the formula I have the preferred region of the structural element A, the preferred region of the structural element E and the preferred, region of the structural element G, while the structural element L may vary widely as described above.
Extremely preferred compounds of the formula I have the preferred structural element A of the formula IA" and the preferred regions of the structural elements E, G and L.
Very preferred compounds of the formula I are listed in the following table, where "compound number" stands for the number of an individualized compound A-E-G-L of the formula I, the compound number and the respective compound are separated by a colon, and the meaning of the abbreviations of the structural elements A-E-G-L is explained after the table.

Compound number: A-E-G-L
1: bhs-25thiaz-nmgly-betaoxaz 2: phhs-24thiaz-bala-betabph 3: bhs-25thiaz-ser-betapy 4: thazep-24thiaz~ly-beta13bendi 5: bim-24thiaz-gly-betatrif 6: bhs-24thioph-gly-betapyee 7: bhs-me25thioph-ala-beta34meoph 8: tolhs-24thioph-gly-betafbph 9: tolhs-24thioph-gly-betameph 10: bim-me24thiaz-bala-betaph 11: bhs-me25thioph-leu-beta34meoph 12: ibhs-24thioph-gly-betathiome 13: bhs-nme35pyr-gly-betabthioph 14: tolhs-nme35pyr-gly-betafu2 15: bhs-ithiadiaz-gly-betahmofu 16: phhs-nme35pyr-bala-betacph 17: impy-24thiaz-bala-betafu3 18: tolhs-25methiaz-bala-psdaptb 19: sabhs-25thiaz-gly-psdap 20. bhs-24thioph-gly-betadcphtb 21: 2py-nme35pyr-leu-psdap 22: bhs-nme35pyr-gly-aspbzla 23: phhs-me24thiaz-gly-zdap 24: bhs-25thiaz-bala-betameph 25: phhs-me24thiaz-ala-beta34meoph 26: tolhs-25methiaz-gly-beta34meoph 27: ibhs-ithiadiaz-gly-betafbph 28: tolhs-ithiadiaz-bala-asppha 29: phhs-ithiadiaz-baia-betaamibe 30: tolhs-24thioph-bala-betabmph 31: phhs-25methiaz-bala-betaol 32: bhs-25oxaz-bala-betamethi 33: ibhs-24thiaz-bala-betahni 34: gua-24thiaz-gly-betaftrif 35: bhs-24thiaz-gly-betafphe WO 00166618 PCTlEP00103469 _27_ 36: tolhs-oxadiaz-gly-psdaptb 37: phhs-25methiaz-bala-betatbuph 38: bhs-24thiaz-nmgly-betathio3 39: phhs-24thioph-gly-betatos 40: 2py-thiadiaz-leu-psdap 41: dhim-35py-gly-betameph 42: bhs-ithiadiaz-gly-aspaba 43: phhs-oxadiaz-gly-beta4bph 44: bhs-25thiaz-gly-csdap 45: ibhs-25thiaz-gly-betahph 46: phhs-25methiaz~ly-betahdbph 47: bim-me25thioph-gly-betaph 48: ibhs-ithiadiaz-bala-beta3quin 49: tolhs-oxadiaz-gly-betadhbfu 50: bhs-oxadiaz-leu-psdap 51: impy-24thioph-bala-betainyl 52: bhs-25methiaz-ala-beta23meoph 53: phhs-24thiaz-gly-betabnaphth 54: impy-42nmeim-bala-betathiome 55: bim-35thioph-ala-betadcph 56: 2py-me24thiaz-gly-betapy 57: phhs-24thioph-bala-betaimid 58: phhs-24thioph-gly-betadhbfu 59: phhs-nme35pyr-bala-betaibph 60: bhs-25thiaz-ser-betameph 61: tolhs-25thiaz-bala-zdap 62: bim-25thiaz-gly-betadcph 63: 2pmhs-42nmeim-gly-betaamibe 64: 2py-24thioph-gly-beta3quin 65: bhs-25methiaz-gly-betamethioph 66: tolhs-ithiadiaz-gly-betafbph 67: phhs-25methiaz-gly-betamethi 68: ibhs-24thiaz-gly-betadtrif 69: bhs-24thioph-gly-betabthioph 70: tolhs-25oxaz-gly-betabmph 71: ibhs-ithiadiaz-bala-suabu 72: bhs-42oxaz-gly-betapy WO 00!66618 PCTIEP00103469 73: tolhs-ithiadiaz-g1y-betapyr 74: 2py-24im-g ly-psdap 75: thpy-24thiaz-gly-betadcph 76: phhs-24thiaz-gly-betampy 77: bhs-25methiaz-bala-betadito 78: phhs-25methiaz-bala-suabu 79: bhs-25thiaz-bala-beta23meoph 80: bhs-oxadiaz-leu-betapy 81: tolhs-25oxaz-gly-betabnaphth 82: dhim-25thiaz-ala-zdap 83: tolhs-ithiadiaz-gly-betaimid 84: bhs-ithiadiaz-bala-betaoxaz 85: bim-25thioph-ala-betameph 86: phhs-25oxaz-bala-beta4bph 87: bhs-nme35pyr-nmgly-betainyl 88: phhs-24thiaz-bala-betacbph 89: bhs-25oxaz-bala-betaet 90: bhs-24thioph-bala-betabmph 91: bhs-25oxaz-ala-betaanaphth 92: ibhs-ithiadiaz-gly-betathiobe 93: bhs-25thiaz-bala-betadito 94: 2py-nme35pyr-bala-betapy 95: tolhs-25oxaz-bala-beta3quin 96: bhs-25thiaz-gly-beta23meoph 97: 2py-25methiaz-gly-betadito 98: ibhs-nme35pyr-bala-betahni 99: tolhs-nme35pyr-gly-betadmph 100:ibhs-ithiadiaz-bala-betabdimo 101:2py-24thiaz-gly-aspibua 102:ibhs-nme35pyr-bala-betacbph 103;bhs-24thiazme-gly-zdap 104:bhs-24thioph-bala-betaol 105:2py-24im-gly-zdap 106:tolhs-25methiaz-gly-betapytb 107:tolhs-ithiadiaz-gly-psdap 108:phhs-25thiaz-bala-betabthioph 109:bhs-nme35pyr-gly-betafph WO 00!66618 PCTIEP00103469 110:bhs-25methiaz-ala-betadhbfu 111:bim-25fur-ala-psdap 112:2pmhs-24thiaz-gly-betapy 113:bhs-24thiaz-bala-betaphethio 114:bhs-25methiaz-bala-betapytb 115:bhs-25methiaz-bala-betambiph 116:ibhs-25thiaz-gly-betainyl 117:phhs-nme35pyr-bala-betabthioph 118:bhs-25thiaz-bala-betacph 119:bim-26py-ala-betadcph 120:phhs-24thioph-gly-betaphethio 121:gua-24thiaz-gly-betabthioph 122:phhs-24thioph-bala-betaph 123:bhs-25thiaz-gly-betaibph 124:ibhs-nme35pyr-bala-betathio3 125:tolhs-oxadiaz-gly-betapy 126:tolhs-nme35pyr-bala-beta4bph 127:2py-me24oxaz-gly-betadcph 128:tolhs-25methiaz-bala-psdapee 129:bhs-ithiadiaz-gly-suabu 130:ibhs-25methiaz-bala-beta3quin 131:phhs-25oxaz-gly-betaipr 132:bim-53pyrazo-ala-betadcph 133:tolhs-25oxaz-gly-betapym 134:phhs-25oxaz-gly-betathiobe 135:phhs-me24thioph-ala-betaph 136:tolhs-me25thiaz-leu-betapy 137:hs-25thiaz-bala-betapy 138:bim-42nmeim-leu-betapy 139:tolhs-nme35pyr-bala-betampy 140:bhs-24thioph-gly-betahdcph 141:ibhs-25oxaz-gly-betaimid 142:bhs-oxadiaz-gly-csdap 143:ibhs-25oxaz-gly-betadtrif 144:2py-53pyrazo-ala-betapy 145:phhs-nme35pyr-gly-betahdbph 146:tolhs-oxadiaz-bala-zdapch 147:phhs-oxadiaz-bala-betapych 148:bim-24thioph-gly-betatrif 149:tolhs-25methiaz-bala-betapyr 150:2py-24thiaz-ala-betapy 151:bhs-25thiaz-gly-betapytb 152:tolhs-25oxaz-gly-zdapch 153:bhs-25methiaz-ala-betadcph 154:ibhs-25methiaz-gly-betatos 155:tolhs-25thiaz-gly-beta35dbph 156:bim-me24thioph-leu-betadcph 157:bim-nme35pyr-gly-aspbzla 158:ibhs-24thioph-bala-ibsdap 159:gua-24thiaz-gly-betal3bendi 160:2py-25meth iaz-g ly-psda p 161:2py-24thiaz-bala-asppha 162:ibhs-ithiadiaz-bala-betaanaphth 163:bhs-nme35pyr-ala-betameph 164:tolhs-oxadiaz-gly-betapym 165:phhs-ithiadiaz-gly-betaph 166:phhs-25methiaz-bala-betadcphtb 167:2pmhs-24thiaz-gly-betaph 168:gua-24oxaz-gly-betafbph 169:bhs-25oxaz-phg-betapy 170:bhs-25methiaz-bala-betahdbph 171:2py-me24thiaz-baia-beta34meoph 172:bhs-25thiaz-bala-betambiph 173:phhs-25methiaz-bala-betadmph 174:bhs-oxadiaz-gly-zdapch 175:dhim-25thioph-gly-betadcph 176:bhs-me25oxaz-gly-zdap 177:ibhs-oxadiaz-gly-betahmo 178:ibhs-25thiaz-gly-betadcph 179:2py-35fur-gly-zdap 180:bhs-24thiaz-ala-beta13bendi 181:bhs-oxadiaz-gly-betadcph 182:phhs-oxadiaz-bala-betah35dc 183:ibhs-oxadiaz-bala-betaet WO 00166618 PCTIEP00l03469 184:phhs-nme35pyr-gly-betadmph 185:phhs-me24thioph-bala-betapy 186:tolhs-25oxaz-gly-beta34dcph 187:bim-26py-gly-betameph 188:ibhs-24thiaz-gly-betadcphee 189:phhs-25thiaz-gly-betacbph 190:tolhs-ithiadiaz-gly-betaphethioa 191:bhs-25methiaz-gly-betafu2 192:2pmhs-42nmeim-gly-betabenfu 193:bhs-25methiaz-gly-beta3quin 194:tolhs-25thiaz-bala-betahdcph 195:2py-24thioph-bala-betadcph 196:2py-42nmeim-ala-zdap 197:bim-35thioph-gly-betapy 198:bim-me25thioph-leu-zdap 199:bim-25methiaz-bala-betapy 200:tolhs-25thiaz-bala-betaoxaz 201:phhs-25oxaz-gly-betapbiph 202:tolhs-24thioph-bala-ibsdap 203:bhs-oxadiaz-gly-zdaptb 204:bim-42oxaz-leu-betapy 205.ibhs-25methiaz-gly-zdaptb 206:ibhs-25methiaz-gly-betaol 207:tolhs-ithiadiaz-gly-beta34dcph 208:phhs-ithiadiaz-gly-betacthioph 209:phhs-24thiaz-bala-betahmofu 210:phhs-ithiadiaz~ly-aspibua 211:phhs-24thiaz-gly-betathioph 212:bhs-25methiaz-gly-betaimid 213:gua-25thiaz-gly-betahdcph 214:bhs-25thiaz-ala-betacph 215:gua-24thiaz-gly-betaet 216:tolhs-25methiaz-bala-betahcbph 217:tolhs-ithiadiaz-gly-beta35dbph 218:ibhs-oxadiaz-gly-betadbph 219:tolhs-24thioph-gly-betathioph 220:bim-53pyrazo-bala-zdap 221: bim-me24oxaz-gly-betadcph 222: bim-triaz-gly-psdap 223: phhs-25thiaz-bala-betampy 224: bhs-oxadiaz-gly-betadcphee 225: bim-ithiadiaz-leu-zdap 226: 2pmhs-24thiaz-gly-betafph 227: bhs-25thiaz-gly-betathioph 228: gua-24thiaz-bala-betadcph 229: impy-42nmeim-bala-betafph 10230: tolhs-24thioph-gly-betadmoph 231: ibhs-oxadiaz-bala-betapbiph 232: ibhs-25methiaz-bala-zdapee 233: tolhs-oxadiaz-gly-betafph 234: bhs-me24oxaz-bala-beta34meoph 15235: tolhs-25methiaz-bala-betahbcph 236: bim-42oxaz-leu-betadcph 237: tolhs-oxadiaz-gly-busu2be 238: tolhs-me25thiaz-ala-betapy 239: phhs-oxadiaz-bala-betainyl 20240: bhs-oxadiaz-gly-psdaptb 241: phhs-24thiaz-gly-busu2be 242: tolhs-25methiaz-bala-zdapee 243: bhs-25thiaz-nmgly-betahmph 244: bhs-oxadiaz-gly-betapy 25245: phhs-25oxaz-gly-betadcphee 246: phhs-24thiaz-gly-betapy 247: tolhs-ithiadiaz-bala-betamesu 248: bhs-25oxaz-nmgly-beta13bendi 249: phhs-24thiaz-gly-psdapch 30250: phhs-25oxaz-bala-asppha 251: phhs-25oxaz-bala-beta3quin 252: phhs-25methiaz-gly-beta3quin 253: phhs-me25oxaz-bala-betadcph 254: phhs-me24thiaz-ala-psdap 35255: ibhs-24thioph-gly-betapych 256: phhs-ithiadiaz-bala-betaibph 257: bhs-25oxaz-bala-betaftrif WO 00166618 PCTlEP00103469 258:bhs-24thiaz-bala-betahc 259:2py-me24thioph-leu-psdap 260:phhs-24thioph-gly-betahc 261:dhim-26py-gly-betaheph 262:phhs-oxadiaz-bala-betaphethio 263:bhs-42nmeim-gly-betahni 264:tolhs-nme35pyr-bala-betahb 265:ibhs-nme35pyr-gly-betathiobe 266:tolhs-25oxaz-gly-betapytb 267:2py-me24oxaz-ala-beta34meoph 268:ibhs-ithiadiaz-gly-betahph 269:bhs-25methiaz-ala-beta13bendi 270:gua-26py-gly-beta3quin 271:phhs-ithiadiaz-gly-betathiobe 272:bhs-oxadiaz-gly-betabpy 273:ibhs-25thiaz-bala-psdapch 274:phhs-ithiadiaz-gly-betacph 275:phhs-24thioph-gly-betabthioph 276:gua-24thiaz-gly-betamesu 277:tolhs-24thiaz-gly-betambiph 278:bhs-me24oxaz-leu-betaph 279:2pmhs-25methiaz-gly-betabpy 280:bhs-ithiadiaz-bala-betathiobe 281:tolhs-25methiaz-bala-betafphe 282:tolhs-24thiaz-bala-betahni 283:ibhs-25thiaz-gly-zdap 284:bhs-25thiaz-ala-betaanaphth 285:ibhs-ithiadiaz-bala-betaphethio 286:ibhs-25oxaz-gly-betaheph 287:2py-me25thioph-leu-zdap 288:phhs-me24thiaz-bala-betaph 289:bim-me25thioph-bala-betapy 290:2py-25thiaz-bala-betapy 291:phhs-25thiaz-bala-betatbuph 292:bhs-24thioph-ala-beta13bendi 293:tolhs-25methiaz-bala-betathiobe 294:phhs-25thiaz-bala-beta13bendi 295:bim-nme35pyr-leu-psdap 296:phhs-25methiaz-gly-betatos 297:tolhs-nme35pyr-bala-betaibph 298:phhs-25oxaz-bala-betadcphee 299:hs-24thioph-bala-betapy 300:bim-42nmeim-gly-psdap 301:ibhs-nme35pyr-bala-betambiph 302:bhs-nme35pyr-bala-betahdcph 303:tolhs-ithiadiaz-bala-beta34meoph 304:bhs-25methiaz-ala-betahph 305:bim-53pyrazo-bala-psdap 306:2pmhs-25thiaz-gly-betahb 307:2py-me24thiaz-leu-betadcph 308:gua-24thiaz-gly-betahmph 309:ibhs-nme35pyr-gly-betaimid 310:phhs-24thiaz-bala-zdaptb 311:tolhs-24thiaz-gly-betaph 312:gua-24thiaz-gly-betahdcph 313:bhs-25methiaz-bala-betapyee 314:2py-42nmeim-gly-csdap 315:bhs-25oxaz-ala-betadito 316:bhs-nme35pyr-gly-betafu3 317:ibhs-25oxaz-bala-betahdbph 318:phhs-nme35pyr-gly-betabmph 319:phhs-ithiadiaz-bala-betapych 320:bim-24thiaz-leu-psdap 321:bhs-oxadiaz-bala-betadcphee 322:tolhs-ithiadiaz-bala-betaol 323:gua-42pym-gly-betabediox 324:bim-24thiaz-gly-asppha 325:tolhs-24thiaz-gly-betahmofu 326:ibhs-oxadiaz-gly-beta23meoph 327:phhs-me24thioph-ala-zdap 328:phhs-me24oxaz-gly-betaph 329:bhs-25oxaz-nmgly-beta23meoph 330:tolhs-ithiadiaz-bala-betadbph 331:bhs-24im-bala-zdap WO 00/66618 PCTlEP00103469 332:phhs-oxadiaz-gly-busu2be 333:ibhs-25methiaz-bala-betathio3 334:tolhs-24thiaz-bala-betabdimo 335:bhs-25oxaz-bala-betaipr 336:2py-me25thiaz-ala-betaph 337:bhs-25methiaz-gly-betapyr 338:tolhs-25oxaz-bala-betainyl 339:ibhs-25oxaz-gly-betaoxaz 340:tolhs-25thiaz-gly-betapyr 341:phhs-25methiaz-bala-betacbph 342:bhs-24thioph-gly-betadmoph 343:tolhs-oxadiaz-bala-aspbzla 344:dhim-25thioph-gly-zdap 345:phhs-25oxaz-bala-betafph 346:tolhs-25methiaz-bala-betaoxaz 347:ibhs-nme35pyr-bala-aspbzla 348:bhs-oxadiaz-bala-betahcbph 349:phhs-oxadiaz-gly-betameph 350:phhs-me24thioph-leu-betadcph 351:ibhs-nme35pyr-gly-busu2be 352:dhim-24oxaz-ala-zdap 353:2py-me24oxaz-ala-betaph 354:phhs-ithiadiaz-gly-betampy 355:bhs-ithiadiaz-gly-psdap 356:ibhs-24thioph-gly-aspbzla 357:bim-ithiadiaz-leu-psdap 358:dhim-24thiaz-gly-betahdcph 359:bim-me25oxaz-ala-betadcph 360:gua-24thiaz-gly-betaoxope 361:bim-nme35pyr-ala-betadcph 362:phhs-24thioph-bala-betabthioph 363:2py-25methiaz-bala-aspbzla 364:tolhs-nme35pyr-gly-betaet 365:bhs-52thiaz-gly-zdap 366:ibhs-oxadiaz-gly-betafbph 367:bhs-24thiaz-gly-betafu3 368:bim-25thiaz-gly-betapy 369: bhs-24thiaz-gly-betah35dc 370: tolhs-24thiaz-bala-aspibua 371: tolhs-24thioph-bala-betadhbfu 372: tolhs-24thioph-gly-psdapee 373: ibhs-25thiaz-bala-betapym 374: bhs-52thiaz-ala-betainyl 375: ibhs-25oxaz-bala-betadtrif 376: ibhs-ithiadiaz-gly-betamethioph 377: tolhs-25methiaz-gly-betabpy 10378: ibhs-25methiaz-bala-beta35dbph 379: ibhs-25oxaz-bala-beta35dbph 380: bhs-me25thiaz-bala-zdap 381: bhs-25oxaz-gly-asppha 382: bhs-25methiaz-bala-betaphethio 15383: bim-42oxaz-bala-betadcph 384: ibhs-24thiaz-bala-beta3quin 385: bhs-25methiaz-gly-betadcphtb 386: bhs-ithiadiaz-gly-betadcphtb 387: ibhs-25oxaz-bala-betafph 20388: tolhs-24thioph-gly-betahmo 389: bhs-24thioph-bala-betafbph 390: phhs-24thiaz-bala-beta13bendi 391: 2py-24oxaz-bala-zdap 392: phhs-nme35pyr-gly-betadbph 25393: bhs-25methiaz-bala-betacph 394: tolhs-25oxaz-gly-betamethioph 395: ibhs-24thiaz-bala-betambiph 396: bhs-24thioph-nmgly-ibsdap 397: phhs-nme35pyr-bala-betahmph 30398: dhim-52thiaz-ala-betameph 399: tolhs-oxadiaz-gly-beta3quin 400: bhs-25methiaz-nmgly-betaoxaz 401: bhs-oxadiaz-ala-betafphe 402: phhs-25methiaz-gly-betafluo 35403: bhs-25oxaz-leu-betadcph 404: tolhs-25methiaz-gly-betaipr 405: dhim-26py-gly-betahcbph 406:bhs-25methiaz-gly-zdapee 407:2pmhs-24thioph-gly-betahbcph 408:phhs-ithiadiaz-bala-betahc 409:tolhs-24thiaz-gly-betaipr 410:ibhs-nme35pyr-bala-betainyl 411:bhs-42pym-ala-zdap 412:bhs-25oxaz-bala-betaphethio 413:impy-25thiaz-gly-betahmofu 414:bhs-25thiaz-bala-betadmph 415:tolhs-me25thioph-ala-betaph 416:bim-24thioph-gly-aspbzla 417:tolhs-nme35pyr-gly-betaheph 418:phhs-25oxaz-bala-betatrif 419:tolhs-24thioph-gly-betathiome 420:ibhs-nme35pyr-gly-betathioph 421:ibhs-25methiaz-gly-betambiph 422:bhs-25oxaz-bala-betacthioph 423:ibhs-24thiaz-gly-csdap 424:2py-ithiadiaz-gly-asppha 425:tolhs-25thiaz-gly-betabdimo 426:tolhs-25thiaz-gly-zdap 427:tolhs-25methiaz-bala-betadmoph 428:tolhs-25thiaz-gly-betabediox 429:phhs-25methiaz-gly-betadbph 430:ibhs-oxadiaz-gly-betahni 431:tolhs-24thiaz-bala-betahdbph 432:phhs-25oxaz-gly-betadmoph 433:phhs-24thiaz-gly-betaomebendi 434:tolhs-ithiadiaz-bala-zdapee 435:tolhs-25oxaz-gly-betathiobe 436:phhs-25oxaz-bala-betaibph 437:2py-25oxaz-leu-zdap 438:bhs-24oxaz-leu-betadcph 439:bhs-nme35pyr-ala-psdap 440:phhs-oxadiaz-bala-betabediox 441:tolhs-oxadiaz-bala-betapbiph 442:2py-ithiadiaz-bala-aspaba WO 00166618 PCTlEP00103469 443:tolhs-24thiaz-bala-psdaptb 444:bhs-24thiaz-gly-busu2be 445:ibhs-25thiaz-gly-betaoxaz 446:bhs-24thioph-gly-betaphethio 447:bim-35thioph-bala-betapy 448:dimethpym-25methiaz-gly-betameph 449:2py-ithiadiaz-bala-zdap 450:bhs-25thiaz-nmgly-betabpy 451:2py-35fur-ala-betapy 452:phhs-25oxaz-gly-betamethioph 453:tolhs-me24thioph-bala-betapy 454:tolhs-ithiadiaz-gly-betafu3 455:gua-26py-gly-betaimid 456:phhs-nme35pyr-bala-betaphethio 457:bhs-25oxaz-gly-aspibua 458:ibhs-oxadiaz-gly-betafph 459:ibhs-oxadiaz-gly-betafu3 460:ibhs-24thiaz-bala-betahcbph 461:tolhs-24thioph-gly-betafluo 462:2py-24thioph-leu-betapy 463:impy-25oxaz-gly-ibsdap 464:phhs-nme35pyr-gly-aspbzla 465:4pmhs-42nmeim-bala-betadcph 466:tolhs-me25thioph-leu-beta34meoph 467:phhs-oxadiaz-gly-betaoxaz 468:tolhs-nme35pyr-gly-betamethioph 469:bhs-25thiaz-gly-betaheph 470:phhs-nme35pyr-bala-betaoxaz 471:bhs-24thioph-nmgly-betacph 472:bim-me25oxaz-ala-beta34meoph 473:bhs-25methiaz-gly-betacbph 474:impy-25methiaz-gly-betahmofu 475:dhim-35pyrazo-gly-betameph 476:bim-35fur-ala-zdap 477:phhs-25oxaz-gly-betahc 478:bhs-24thioph-bala-aspibua 479:2py-24thiaz-gly-betacthioph 480: bhs-oxadiaz-bala-suabu 481: bhs-25methiaz-gly-aspaba 482: tolhs-nme35pyr-gly-betaipr 483: 2py-ithiadiaz-ala-psdap 484: ibhs-ithiadiaz-bala-betathiobe 485: bhs-nme35pyr-bala-betapyee 486: tolhs-25methiaz-bala-betahc 487: tolhs-25oxaz-gly-zdaptb 488: bhs-24thioph-gly-beta23meoph 10489: tolhs-24thioph-bala-betaphethioa 490: bhs-nme35pyr-bala-betahbcph 491: phhs-25oxaz-gly-betadbph 492: bhs-25methiaz-bala-asppha 493: ibhs-nme35pyr-gly-psdapch 15494: bhs-oxadiaz-bala-ibsdap 495: bhs-25methiaz-bala-betapy 496: ibhs-24thiaz-gly-betabdimo 497: ibhs-24thiaz-bala-beta34dcph 498: phhs-oxadiaz-gly-betadcphch 20499: bim-nme35pyr-gly-betadcph 500: bhs-ithiadiaz-gly-betahc 501: ibhs-ithiadiaz-bala-betathiome 502: bim-me24oxaz-leu-zdap 503: bhs-25oxaz-gly-betadcphee 25504: bim-25fur-leu-psdap 505: tolhs-oxadiaz-bala-betatbuph 506: gua-42pym-gly-betadbph 507: ibhs-24thioph-gly-aspaba 508: ibhs-25methiaz-gly-beta34dcph 30509: tolhs-ithiadiaz-bala-betahbcph 510: bhs-oxadiaz-nmgly-betaoxaz 511: tolhs-25thiaz-bala-betadbph 512: bhs-oxadiaz-bala-betaomebendi 513: thpym-24thiaz-gly-betameph 35514: bhs-ithiadiaz-bala-beta35dbph 515: 2pmhs-25thiaz-gly-betadtrif 516: ibhs-ithiadiaz-bala-psdapch WO 00!6661$ PCTlEP00l03469 517: phhs-24thioph-bala-betaanaphth 518: bhs-25thiaz-bala-betaet 519: ibhs-ithiadiaz-bala-betahdcph 520: bhs-42oxaz-ala-zdap 521: tolhs-24thioph-gly-busu2be 522: bhs-ithiadiaz-gly-betaftrif 523: tolhs-nme35pyr-gly-betadhbfu 524: bhs-24thiaz-gly-aspibua 525: bhs-24thioph-gly-betapy 10526: ibhs-25oxaz-gly-aspbzla 527: tolhs-24thioph-bala-betadbph 528: phhs-25methiaz-gly-betabenfu 529: bhs-nme35pyr-ala-betadito 530: phhs-me25thiaz-ala-beta34meoph 15531: ibhs-25methiaz-bala-betamethi 532: ibhs-25oxaz-gly-betahmofu 533: bhs-24thioph-gly-zdapch 534: phhs-24thioph-bala-betah35dc 535: ibhs-24thioph-bala-betahcbph 20536: ibhs-ithiadiaz-bala-betahph 537: bhs-ithiadiaz-bala-asppha 538: dhim-25thioph-gly-betameph 539: tolhs-ithiadiaz-gly-betadcphee 540: phhs-oxadiaz-bala-betatbuph 25541: bhs-25thiaz-gly-betamethi 542: bhs-ithiadiaz-gly-betahbcph 543: tolhs-25oxaz-bala-betadcphtb 544: phhs-24thiaz-gly-betadhbfu 545: ibhs-25oxaz-gly-psdap 30546: ibhs-25methiaz-bala-betatrif 547: bhs-ithiadiaz-bala-beta23meoph 548: phhs-25thiaz-gly-betahmofu 549: bhs-24thioph-gly-betamethi 550: ibhs-25oxaz-gly-betadito 35551: bhs-25methiaz-gly-betadcph 552: bhs-me24thioph-ala-psdap 553: tolhs-25thiaz-gly-betahni 554:ibhs-24thioph-gly-betafu3 555:phhs-24thiaz-gly-betahni 556:2py-24thioph-gly-aspbzla 557:ibhs-nme35pyr-gly-betaibph 558:tolhs-25methiaz-gly-psdapch 559:bhs-ithiadiaz-gly-betaet 560:bhs-nme35pyr-ala-beta34meoph 561:phhs-oxadiaz-gly-betapyr 562:ibhs-25oxaz-gly-zdapch 563:bhs-24oxaz-ala-betainyl 564:ibhs-nme35pyr-gty-betahmo 565:bhs-25thiaz-nmgly-beta34dcph 566:bhs-nme35pyr-bala-betaomebendi 567:tolhs-25oxaz-gly-betaph 568:bhs-24thiaz-nmgly-betahph 569:bhs-nme35pyr-leu-psdap 570:ibhs-24thioph-gly-betahni 571:ibhs-25oxaz-gly-betaftrif 572:phhs-me24thiaz-leu-zdap 573:ibhs-24thiaz-gly-betathiobe 574:phhs-25oxaz-bala-betabediox 575:phhs-ithiadiaz-gly-betameph 576:tolhs-ithiadiaz-gly-psdaptb 577:2py-me25oxaz-leu-zdap 578:dhim-24oxaz-gly-zdap 579:tolhs-oxadiaz-gly-betapbiph 580:tolhs-24thioph-gly-betadcphch 581:bhs-ithiadiaz-bala-psdapee 582:imhs-25methiaz-gly-zdap 583:bhs-25oxaz-gly-betabnaphth 584:bhs-24thiaz-gly-betaftrif 585:phhs-25methiaz-gly-betahmofu 586:phhs-ithiadiaz-bala-betamethi 587:bhs-ithiadiaz-gly-betabdimo 588:dhim-42pym-gly-betainyl 589:bhs-25thioph-bala-betadcph 590:2py-thiadiaz-leu-betapy 591:tolhs-25oxaz-bala-betabmph 592:phhs-25oxaz-gly-betadito 593:bim-ithiadiaz-gly-psdap 594:phhs-24thioph-gly-betaibph 595:tolhs-25oxaz-gly-psdapee 596:ibhs-25methiaz-gly-betamesu 597:bhs-oxadiaz-bala-aspaba 598:bhs-oxadiaz-bala-betapym 599:phhs-24thioph-gly-betafu3 600:tolhs-24thioph-gly-betaphethioa 601:ibhs-25oxaz-bala-betafphe 602:tolhs-25oxaz-gly-betacbph 603:ibhs-25methiaz-bala-betaipro 604:bhs-nme35pyr-gly-betaipro 605:tolhs-24thioph-bala-betahmph 606:tolhs-25methiaz-bala-betadbph 607:bhs-25methiaz-gly-betaamibe 608:impy-24thiaz-gly-betabediox 609:ibhs-oxadiaz-gly-betapym 610:2py-25methiaz-ala-betapy 611:tolhs-nme35pyr-bala-betabnaphth 612:phhs-24thioph-gly-beta4bph 613:ibhs-ithiadiaz-bala-betah35dc 614:bhs-oxadiaz-gly-betaomebendi 615:tolhs-25methiaz-gly-betafph 616:phhs-25oxaz-bala-betadcphtb 617:ibhs-ithiadiaz-gly-beta35dbph 618:2py-25oxaz-bala-betadhbfu 619:bhs-25oxaz-gly-betatrif 620:ibhs-25thiaz-gly-zdapch 621:bhs-oxadiaz-gly-betadmoph 622:phhs-nme35pyr-bala-betacthioph 623:phhs-25thiaz-bala-betavxaz 624:bim-me25oxaz-gly-psdap 625:bhs-25methiaz-ala-betapy 626:ibhs-24thioph-bala-betathioph 627:phhs-25methiaz-gly-suabu WO 00/66618 PCTIEP00I034fi9 628:phhs-ithiadiaz-bala-betacph 629:phhs-25methiaz-gly-betadmoph 630:phhs-ithiadiaz-bala-zdapch 631:phhs-24thiaz-gly-betabediox 632:bhs-nme35pyr-bala-betatos 633:tolhs-25oxaz-bala-betaipr 634;bhs-24thioph-gly-betapytb 635:bhs-25methiaz-leu-betapy 636:4pmhs-24thiaz-gly-betapy 637:tolhs-oxadiaz-bala-betapytb 638:tolhs-oxadiaz-gly-beta34meoph 639:bhs-25oxaz-bala-betatbuph 640:ibhs-25oxaz-gly-suabu 641:phhs-25methiaz-gly-psdaptb 642:tolhs-25oxaz-bala-betahph 643:ibhs-nnme35pyr-gly-betabmph 644:bhs-25oxaz-gly-betadmph 645:ibhs-25oxaz-bala-betabpy 646:phhs-me24thioph-gly-betadcph 647:tolhs-24thioph-bala-betathio3 648:ibhs-25methiaz-bala-psdap 649:bim-25thiaz-gly-psdap 650:ibhs-25methiaz-gly-betahbcph 651:ibhs-ithiadiaz-gly-betacbph 652:ibhs-25methiaz-gly-betabthioph 653:bim-me24thioph-gly-betadcph 654:bhs-oxadiaz-bala-betatos 655:phhs-nme35pyr-gly-betabdimo 656:gua-26py-gly-betahmofu 657:ibhs-24thioph-gly-psdaptb 658:phhs-25oxaz-bala-betainyl 659:phhs-24thiaz-bala-betameph 660:bim-25thioph-bala-zdap 661:tolhs-25oxaz-bala-betahmo 662:tolhs-ithiadiaz-gly-betacbph 663:tolhs-25methiaz-bala-beta34meoph 664:bhs-24im-gly-betameph 665:tolhs-oxadiaz-gly-betadcphee 666:phhs-25thiaz-gly-betadmph 667:bhs-nme35pyr-ala-betadmoph 668:ibhs-24thiaz-gly-betafphe 669:circa-25oxaz-gly-betameph 670:phhs-25oxaz-gly-betatos 671:phhs-25methiaz-bala-beta3quin 672:bim-24oxaz-ala-zdap 673:ibhs-25methiaz-gly-csdap 674:phhs-ithiadiaz-bala-betafph 675:dhim-52thiaz-gly-psdap 676:bhs-24thiaz-ala-zdap 677;ibhs-ithiadiaz-bala-aspibua 678:ibhs-oxadiaz-bala-betahmofu 679:phhs-24thioph-bala-betaoxaz 680:phhs-25oxaz-bala-busu2be 681:tolhs-25oxaz-bala-ibsdap 682:ibhs-24thioph-gly-betacph 683:bhs-35thioph-ala-betameph 684:2py-25thioph-gly-betainyl 685:bim-nme35pyr-ala-betapy 686:2py-25thiaz-bala-aspaba 687:bhs-24thioph-gly-betabenfu 688:phhs-nme35pyr-bala-betabph 689:ibhs-oxadiaz-gly-betatos 690:phhs-ithiadiaz-gly-betamesu 691:2pmhs-25oxaz-bala-betabnaphth 692:tolhs-25methiaz-bala-busu2be 693:tolhs-25oxaz-gly-betapyr 694:bhs-ithiadiaz-gly-beta34meoph 695:phhs-24thioph-bala-betampy 696:tolhs-nme35pyr-gly-busu2be 697:bhs-25oxaz-gly-psdap 698:phhs-25oxaz-gly-betaph 699:phhs-me25oxaz-gly-zdap 700:bhs-24thioph-gly-betahc 701:ibhs-25thiaz-gly-beta23meoph WO 00166618 PCTIEP00l03469 702:phhs-25methiaz-gly-betabnaphth 703:phhs-24thioph-gly-betabpy 704:tolhs-25oxaz-bala-betatbuph 705:bhs-24thiaz-gly-zdaptb 706:gua-26py-gly-betaph 707:tolhs-me25thiaz-bala-betadcph 708:phhs-24thiaz-bala-betabediox 709:ibhs-25methiaz-gly-betathiobe 710:phhs-24thiaz-gly-beta3quin 711:tolhs-25oxaz-gly-betadmph 712:dhpyrr-25thioph-gly-betadcph 713:phhs-ithiadiaz-gly-betahb 714:hts-42nmeim-gly-zdap 715:dhim-24thiaz-gly-zdap 716:bhs-24thioph-ser-betapy 717:2py-25fur-bala-betadcph 718:bhs-4.2nmeim-bala-betaol 719:bhs-25methiaz-bala-betafphe 720:ibhs-25thiaz-bala-betaipr 721:2py-24thiaz-bala-aspaba 722:phhs-me25thiaz-ala-betadcph 723:phhs-oxadiaz-bala-betadmph 724:tolhs-ithiadiaz-bala-betapych 725:phhs-25oxaz-bala-betapych 726:tolhs-24thiaz-bala-betadbph 727:ibhs-25methiaz-gly-betabenfu 728:bhs-25methiaz-gly-beta4bph 729:bhs-ithiadiaz-gly-betameph 730:phhs-24thioph-bala-betabenfu 731:bhs-25methiaz-nmgly-ibsdap 732:bhs-oxadiaz-gly-betacbph 733:bhs-nme35pyr-gly-betaftrif 734:phhs-25oxaz-gly-suabu 735:bhs-25methiaz-nmgly-betaanaphth 736:bhs-ithiadiaz-bala-betadbph 737:bim-me25oxaz-gly-betaph 738:phhs-24thioph-gly-betaoxaz 739: bhs-42oxaz-gly-zdap 740: bhs-24thiaz-nmgly-betahmph 741: ibhs-ithiadiaz-bala-betapytb 742: bhs-25methiaz-nmgly-betafphe 743: bhs-oxadiaz-ala-beta34meoph 744: bim-53pyrazo-ala-zdap 745: phhs-25methiaz-gly-betadcph 746: phhs-24thioph-gly-zdaptb 747: hts-25oxaz-bala-betadcph 10748: 2py-ithiadiaz-ala-betadcph 749: bim-nme35pyr-gly-betapy 750: phhs-oxadiaz-gly-betatrif 751: ibhs-24thiaz-bala-betabnaphth 752: 2py-25methiaz-gly-beta3quin 15753: phhs-oxadiaz-bala-betapbiph 754: tolhs-25thiaz-gly-betatrif 755: bim-53pyrazo-gly-betapy 756: bhs-ithiadiaz-nmgly-betabnaphth 757: phhs-25thiaz-gly-betadtrif 20758: phhs-nme35pyr-gly-psdapch 759: tolhs-25thiaz-bala-betaomebendi 760: phhs-24thiaz-gly-betaoxope 761: ibhs-oxadiaz-gly-betathio3 762: phhs-oxadiaz-gly-betaph 25763: phhs-oxadiaz-bala-betabph 764: bim-me25thiaz-bala-betaph 765: ibhs-oxadiaz-bala-beta4bph 766: bim-me25thiaz-leu-zdap 767: 2py-25methiaz-ala-psdap 30768: bhs-42oxaz-ala-betadcph 769: bhs-25methiaz-gly-betainyl 770: bim-triaz-gly-betadcph 771: tolhs-24thiaz-bala-betabthioph 772: bhs-nme35pyr-bala-busu2be 35773: bhs-25oxaz-nmgly-betainyl 774: phhs-me25thiaz-gly-betapy 775: bhs-ithiadiaz-gly-beta4bph 776: phhs-me25thiaz-bala-betadcph 777: bhs-25thiaz-gly-zdap 778: phhs-24thiaz-bala-betah35dc 779: tolhs-nme35pyr-bala-betahmofu 780: bhs-24thiaz-bala-betabdimo 781: bim-ithiadiaz-gly-zdap 782: ibhs-24thioph-gly-betadbph 783: bhs-me25oxaz-g1y-betapy 784: bhs-24thiaz-ala-beta23meoph 10785: ibhs-nme35pyr-bala-betapytb 786: bhs-25oxaz-gly-betaamibe 787: bhs-ithiadiaz-gly-betaoxope 788: gua-25thioph-gly-betacthioph 789: bhs-oxadiaz-gly-betapyr 15790: phhs-me25oxaz-ala-beta34meoph 791: bhs-ithiadiaz-gly-betadrnph 792: bim-25methiaz-bala-betaimid 793: ibhs-oxadiaz-bala-betameph 794: ibhs-oxadiaz-bala-betahph 20795: phhs-24thioph-gly-betathio3 796: tolhs-nme35pyr-bala-betapyr 797: ibhs-ithiadiaz-gly-betamethi 798: phhs-24thiaz-bala-beta3quin 799: ibhs-nme35pyr-gly-betaipro 25800: ibhs-oxadiaz-gly-aspbzla 801: bhs-25thiaz-bala-betamesu 802: bim-35fur-bala-zdap 803: tolhs-nme35pyr-gly-betabph 804: phhs-ithiadiaz-bala-betaphethioa 30805: ibhs-nme35pyr-gly-ibsdap 806: bim-24thiaz-feu-betapy 807: thpy-25methiaz-gly-betadcph 808: phhs-24thioph-gly-betabenfu 809: ibhs-25methiaz-gly-betapych 35810: ibhs-oxadiaz-gly-betaph 811: bhs-25thiaz-gly-betaftrif 812: phhs-nme35pyr-bala-betapym WO 00166618 PCTlEP00103469 813:tolhs-25thiaz-gly-betameph 814:2py-25methiaz-bala-betaheph 815:2py-25methiaz-gly-aspaba 816:phhs-24thiaz-bala-betapych 817:bhs-35fur-bala-betadcph 818:phhs-ithiadiaz~ly-suabu 819:2py-42pym-gly-zdap 820:ibhs-ithiadiaz-gly-betaimid 821:tolhs-25oxaz-gly-betahdbph 822:ibhs-25oxaz-bala-betahbcph 823:ibhs-ithiadiaz-bala-betaoxope 824:tolhs-oxadiaz-gly-ibsdap 825:tolhs-nme35pyr-bala-betabenfu 826:bhs-24thioph-gly-betaphethioa 827:bhs-me25thiaz-bala-betadcph 828:tolhs-me24oxaz-bala-betaph 829:phhs-ithiadiaz-bala-betafbph 830:ibhs-24thioph-gly-betabediox 831:tolhs-me25thioph-bala-zdap 832:tolhs-oxadiaz-bala-betapym 833:bhs-25oxaz-gly-zdaptb 834:ibhs-ithiadiaz-bala-beta13bendi 835:bhs-nme35pyr-bala-betatbuph 836:phhs-oxadiaz-gly-betaphethioa 837:dhim-thiadiaz-gly-betameph 838:bhs-24thioph-nmgly-betacthioph 839:phhs-25methiaz-bala-betaoxaz 840:ibhs-24thiaz-gly-betaimid 841:phhs-24thioph-bala-betabnaphth 842:bhs-24im-bala-betapy 843:toihs-24thiaz-gly-betabph 844:2py-25meth iaz-g ly-aspbzla 845:2pmhs-25thiaz-phe-zdap 846:2pm hs-24th iaz-g ly-betahb 847:bhs-24thiaz-gly-betambiph 848:phhs-25oxaz-gly-psdapch 849:ibhs-24thiaz-gly-beta4bph 850: bim-ithiadiaz-bala-betadcph 851: tolhs-25thiaz-gly-betahdcph 852: bhs-ithiadiaz-bala-betamethioph 853: ibhs-25oxaz-gly-ibsdap 854: ibhs-25oxaz-gly-betabthioph 855: bhs-25methiaz-leu-psdap 856: bhs-25thiaz-bala-betabph 857: tolhs-nme35pyr-bala-betaanaphth 858: bim-me24thioph-leu-betaph 859: thpy-42pym-gly-betadcph 860: thpy-25oxaz-bala-zdap 861: ibhs-ithiadiaz-bala-betahmofu 862: ibhs-oxadiaz-gly-betabph 863: bhs-24thiaz-bala-beta13bendi 864: dhim-24oxaz-ala-betainyl 865: tolhs-nme35pyr-gly-betaoxaz 866: tolhs-oxadiaz-gly-betathio3 867: bhs-25fur-gly-zdap 868: bim-24im-ala-psdap 869: ibhs-nme35pyr-bala-betabmph 870: bhs-ithiadiaz-ala-betathio3 871: tolhs-25thiaz-gly-beta34meoph 872: tolhs-24thioph-gly-betahmofu 873: phhs-25oxaz-gly-zdap 874: 2pmhs-42nmeim-bala-betabph 875: tolhs-25oxaz-bala-busu2be 876: phhs-ithiadiaz-gly-betathioph 877: bhs-25fur-ala-psdap 878: tolhs-25methiaz-bala-betaphethio 879: phhs-oxadiaz-bala-betathiobe 880: ibhs-24thioph-gly-betaibph 881: tolhs-25thiaz-gly-betadito 882: tolhs-25thiaz-gly-betahc 883: tolhs-24thiaz-bala-betabenfu 884: 2py-25thiaz-bala-aspibua 885: impy-25thiaz-gly-betaipr 886: phhs-ithiadiaz-bala-beta35dbph 887: phhs-25thiaz-bala-suabu 888: phhs-24thiaz-bala-betapym 889: dhim-52thiaz-gly-zdap 890: ibhs-24thioph-bala-betathiome 891: bim-42nmeim-bala-betadcph 892: tolhs-ithiadiaz-gly-betaoxaz 893: phhs-25thiaz-bala-betamethi 894: phhs-24thiaz-gly-betaphethioa 895: bhs-ithiadiaz-ala-betacthioph 896: phhs-nme35pyr-bala-betahbcph 897: phhs-me24thiaz-bala-betadcph 898: hs-25oxaz-gly-betadcph 899: ibhs-25oxaz-gly-beta3quin 900: tolhs-24thioph-bala-betaibph 901: tolhs-24thioph-bala-betahb 902: thazep-24thiaz-gly-betapy 903: ibhs-nme35pyr-bala-beta3quin 904: tolhs-25oxaz-bala-betaamibe 905: bhs-oxadiaz-ala-zdap 906: tolhs-24thioph-bala-beta4bph 907: phhs-ithiadiaz-bala-betapbiph 908: gua-42pym-gly-betafph 909: phhs-nme35pyr-gly-betatbuph 910: tolhs-nme35pyr-bala-beta34dcph 911: phhs-24thiaz-bala-aspibua 912: 2py-25thioph-ala-betameph 913: bim-me25thioph-leu-beta34meoph 914: 2py-me25oxaz-leu-betapy 915: 2py-24thioph-gly-aspibua 916: ibhs-25oxaz-gly-betadcphtb 917: gua-42pym-gly-betadcph 918: bhs-24thiaz-bala-betadcphee 919: tolhs-25oxaz-bala-psdapee 920: tolhs-oxadiaz-bala-betaftrif 921: ibhs-oxadiaz-gly-betatbuph 922: bhs-me24oxaz-ala-betadcph 923: tolhs-ithiadiaz-bala-betafu3 WO 00!66618 PCTlEP00103469 924:ibhs-24thioph-bala-zdaptb 925:phhs-25thiaz-bala-betadbph 926:2py-42oxaz-leu-zdap 927:bhs-oxadiaz-bala-betahmofu 928:ibhs-25methiaz-gly-betathiome 929:phhs-nme35pyr-bala-betadito 930:phhs-24thioph-gly-beta34meoph 931:tolhs-nme35pyr-bala-betainyl 932:phhs-me24thioph-gly-beta34meoph 933:bim-me25thiaz-gly-betadcph 934:bhs-24thiaz-ala-csdap 935:phhs-24thioph-gly-aspbzla 936:bim-25thiaz-gly-betatrif 937:impy-24thioph-gly-betacbph 938:dhpyrr-25methiaz-gly-betapy 939:bhs-24thiaz-bala-betadmoph 94~:bhs-42pym-gly-psdap 941:phhs-ithiadiaz-bala-betapyee 942:phhs-24thioph-bala-betathiobe 943:bim-35thioph-leu-psdap 944:phhs-me24oxaz-leu-betapy 945:phhs-24thioph-bala-betacph 946:ibhs-25methiaz-bala-betatos 947:tolhs-25oxaz-bala-betaoxope 948:gua-24oxaz-gly-betamethioph 949:tolhs-25methiaz-gly-suabu 95Q:phhs-24thiaz-bala-betamethi 951:phhs-ithiadiaz-gly-betadhbfu 952:gua-24thiaz-gly-betadbph 953:bhs-25methiaz-nmgly-betabnaphth 954:bhs-24thioph-leu-betapy 955:phhs-25thiaz-gly-betacthioph 956:bim-25oxaz-bala-aspaba 957:phhs-ithiadiaz-bala-psdapee 958:tolhs-oxadiaz-bala-busu2be 959:phhs-me24thiaz-bala-betapy 960:phhs-me24thioph-leu-beta34meoph 961:phhs-24thioph-gly-betapbiph 962:bhs-ithiadiaz-bala-beta34dcph 963:bim-me24thiaz-ala-betaph 964:bhs-nme35pyr-bala-psdapch 965:phhs-24thiaz-bala-betabmph 966:phhs-24thiaz-gly-betadmph 967:bim-triaz-ala-zdap 968:thpym-25oxaz-gly-betameph 969:bim-24thiaz-gly-betaibph 970:tolhs-24thiaz-gly-betaheph 971:tolhs-ithiadiaz-gly-zdaptb ' 972:bim-26pyrazi-gly-zdap 973:ibhs-24thioph-gly-betaol 974:bim-me25thiaz-gly-betaph 975:ibhs-25methiaz-bala-betadcphch 976:phhs-24thioph-gly-psdapch 977:phhs-24thioph-gly-betahdbph 978:phhs-me25oxaz-gly-betapy 979:dhim-24thiaz-gly-betadcph 980:bim-me24thiaz-ala-betadcph 981:bhs-nme35pyr-gly-betaomebendi 982:phhs-oxadiaz-bala-psdapee 983:bhs-24thioph-bala-betahc 984:ibhs-24thiaz-bala-betathiobe 985:bhs-25methiaz-gly-beta13bendi 986:phhs-oxadiaz-bala-busu2be 987:phhs-ithiadiaz-gly-betafu3 988:phhs-24thioph-gly-betaimid 989:tolhs-25thiaz-bala-beta35dbph 990:bhs-oxadiaz-gly-betacthioph 991:bhs-ithiadiaz-gly-betapych 992:bim-24oxaz-gly-psdap 993:tolhs-me24thiaz-bala-betapy 994:bhs-25oxaz-gly-betathio3 995:bim-oxadiaz-bala-betadcph 996:phhs-nme35pyr-gly-betafu3 997:dhim-25thiaz-ala-betapy 998: agua-25methiaz-gly-psdap 999: bim-nme35pyr-leu-zdap 1000:tolhs-24thiaz-bala-betahmo 1001:bim-35fur-bala-psdap 1002:bhs-24thiaz-gly-betadmoph 1003:dhim-25methiaz-gly-betapy 1004:phhs-25methiaz-gly-betapytb 1005:2py-me25oxaz-leu-beta34meoph 1006:gua-24thiaz-gly-betapym 101007:bim-35fur-leu-zdap 1008:bhs-25thioph-leu-betadcph 1009:ibhs-25thiaz-bala-betameph 1010:bhs-24thioph-gly-psdap 1011:2py-35fur-gly-psdap 151012:ibhs-oxadiaz-bala-busu2be 1013:ibhs-oxadiaz-bala-zdap 1014:bhs-25methiaz-gly-betahb 1015:tolhs-25oxaz-bala-beta4bph 1016:phhs-me24oxaz-bala-beta34meoph 201017:tolhs-25oxaz-gly-beta4bph 1018:bim-35thioph-gly-betadcph 1019:bhs-25oxaz-bala-beta3quin 1020:impy-25thiaz-gly-betabediox 1021:bhs-nme35pyr bala-betabmph 251022:phhs-me24oxaz-gly-beta34meoph 1023:tolhs-24thioph-bala-betaipr 1024:2py-me25thioph-leu-betadcph 1025:ibhs-24thiaz-bala-betaol 1026:ibhs-24thioph-gly-betatos 301027:phhs-25thiaz-gly-betahni 1028:tolhs-24thioph-bala-betamethi 1029:tolhs-24thiaz-gly-betafu2 1030:ibhs-ithiadiaz-gly-betathioph 1031:2py-42nmeim-ala-betadcph 351032:phhs-24thioph-bala-aspibua 1033:2py-25thiaz-gly-zdap 1034:bhs-25thiaz-gly-psdapch WO 00166618 PCTlEP00l03469 1035:gua-42pym-gly-betadito 1036:ibhs-25oxaz-gly-betahdcph 1037:tolhs-oxadiaz-bala-betathiome 1038:phhs-25thiaz-bala-betaftrif 1039:phhs-ithiadiaz-bala-betabdimo 1040:bhs-nme35pyr-ala-beta13bendi 1041:ibhs-25methiaz-gly-betadtrif 1042:dhim-25thiaz-gly-betainyl 1043:bim-24thiaz-bala-betapy 1044:bhs-25thiaz-nmgly-betathioph 1045:bhs-25thiaz-gly-betatbuph 1046:tolhs-ithiadiaz-gly-aspibua 1047:phhs-ithiadiaz-bala-ibsdap 1048:bhs-24thiaz-bala-zdaptb 1049:ibhs-25methiaz-gly-busu2be 1050:tolhs-oxadiaz-bala-betahmph 1051:phhs-ithiadiaz-gly-csdap 1052:impy-24thioph-bala-psdap 1053:bim-me25thiaz-leu-psdap 1054:phhs-ithiadiaz-gly-ibsdap 1055:bhs-25methiaz-gly-betah35dc 1056:bhs-25thiaz-met-betameph 1057:tolhs-25methiaz-bala-betainyl 1058:phhs-25thiaz-gly-beta23meoph 1059:phhs-24thioph-gly-betafu2 1060:phhs-me24oxaz-gly-betadcph 1061:tolhs-25thiaz-bala-betah35dc 1062:bhs-24thioph-bala-psdapch 1063:bhs-me24thioph-gly-beta34meoph 1064:tolhs-me24thiaz-ala-betaph 1065:phhs-25methiaz-bala-betaibph 1066:ibhs-ithiadiaz-gly-betadcph 1067:phhs-24thiaz-gly-aspbzla 1068:tolhs-25methiaz-bala-betabdimo 1069:bhs-24thioph-ala-betadmph 1070:gua-42pym-gly-betahcbph 1071:ibhs-25oxaz-bala-betamesu 1072:ibhs-25thiaz-bala-betahcbph 1073:bhs-24thiaz-gly-betabediox 1074:bhs-24thiaz-ala-betamesu 1075:gua-42pym-gly-betaet 1076:bhs-oxadiaz-bala-betathiome 1077:ibhs-25thiaz-gly-betahb 1078:tolhs-ithiadiaz-bala-betadcphtb 1079:bhs-24thiaz-bala-betaoxaz 1080:bhs-24thioph-gly-zdap 1081:bim-nme35pyr-bala-betapy 1082:ibhs-ithiadiaz-gly-beta23meoph 1083:bhs-25thiaz-ala-beta34meoph 1084:tolhs-me25thioph-bala-betadcph 1085:bhs-ithiadiaz-bafa-betaol 1086:phhs-24thiaz-gly-betacbph 1087:phhs-25methiaz-bala-betabenfu 1088:bim-nme35pyr-leu-betapy 1089:2py-35fur-leu-zdap 1090:ibhs-24thioph-gly-betabpy 1091:tolhs-25thiaz-bala-betathiome 1092:phhs-24thioph-bala-busu2be 1093:tolhs-oxadiaz-gly-betaphethio 1094:dhim-26py-ala-betathioph 1095:phhs-nme35pyr-gly-beta34dcph 1096:ibhs-25oxaz-bala-beta23meoph 1097:bhs-25thiaz-ala-zdap 1098:dhthi-24thiaz-bala-betadcph 1099:bhs-nme35pyr-bala-betaoxaz 1100:ibhs-25methiaz-bala-betapytb 1101:ibhs-nme35pyr-gly-betapytb 1102:tolhs-24thiaz-bala-betamesu 1103:bhs-24thioph-gly-betafu3 1104:tolhs-oxadiaz-gly-betabenfu 1105:tolhs-nme35pyr-gly-betafbph 1106:bim-ithiadiaz-bala-zdap 1107:gua-25thioph-gly-suabu 1108:bhs-oxadiaz-gly-betathiobe 1109:phhs-25oxaz-gly-betafluo 1110:2py-me25oxaz-leu-psdap 1111:ibhs-25oxaz-bala-betahni 1112:ibhs-oxadiaz-gly-betaol 1113:tolhs-25thiaz-gly-betaftrif 1114:tolhs-25oxaz-bala-betabdimo 1115:tolhs-25oxaz-gly-asppha 1116:bhs-me24thiaz-ala-betaph 1117:tolhs-24thiaz-gly-betafbph 1118:2py-oxad iaz-g ly-psdap 1119:bhs-25thiaz-bala-betahb 1120:bim-35fur-leu-psdap 1121:bhs-ithiadiaz-nmgiy-ibsdap 1122:bhs-24oxaz-ala-betameph 1123:bhs-nme35pyr-bala-betapyr 1124:bhs-nme35pyr-ala-betapy 1125:tolhs-24thioph-gly-betaftrif 1126:phhs-25oxaz-gly-betaphethioa 1127:tolhs-nme35pyr-gly-csdap 1128:2py-25fur-bala-zdap 1129:2py-24oxaz-leu-psdap 1130:tolhs-24thiaz-bala-zdapch 1131:phhs-oxadiaz-gly-betaoxope 1132:ibhs-24thiaz-bala-betapym 1133:thpym-24thiaz-gly-beta35dbph 1134:phhs-ithiadiaz-bala-betadmph 1135:phhs-me25thiaz-leu-betaph 1136:phhs-nme35pyr-bala-betadcphch 1137:2py-me24thiaz-bala-betaph 1138:phhs-me24thioph-ala-betapy 1139:ibhs-25thiaz-bala-csdap 1140:tolhs-oxadiaz-bala-betaamibe 1141:ibhs-nme35pyr-gly-betabenfu 1142:bhs-25thiaz-gly-betainyl 1143:bhs-25thiaz-gly-betahdcph 1144:phhs-25thiaz-gly-betacph 1145:phhs-oxadiaz-gly-betafph 1146:phhs-25oxaz-gly-betapym 1147:tolhs-24thiaz-bala-betacph 1148:2py-me24thioph-ala-betaph 1149:ibhs-24thiaz-bala-betaipro 1150:hyd-25thiaz-bala-betameph 1151:bim-52thiaz-ala-betapy 1152:bim-me25thiaz-ala-beta34meoph 1153:bhs-oxadiaz-bala-betabmph 1154:dhim-24thiaz-ala-psdap 1155:ibhs-24thioph-bala-zdapee 1156:gua-25thiaz-gly-betahbcph 1157:bhs-ithiadiaz-bala-betabthioph 1158:tolhs-24thiaz-bala-beta13bendi 1159:bim-me24oxaz-ala-beta34meoph 1160:bim-me25oxaz-gly-betapy 1161:2py-25methiaz-gly-aspibua 1162:bim-25thiaz-leu-betapy 1163:bhs-25thiaz-gly-betah35dc 1164:tolhs-25thiaz-bala-betafbph 1165:bhs-24thioph-bala-csdap 1166:dhim-25thiaz-gly-betahdcph 1167:bhs-25oxaz-nmgly-betacthioph 1168:tolhs-24thiaz-gly-betadcphtb 1169:2py-25methiaz-bala-psdap 1170:bim-ithiadiaz-gly-betadcph 1171:bim-25fur-gly-psdap 1172:tolhs-ithiadiaz-gly-psdapch 1173:bhs-53pyrazo-gly-betadcph 1174:ibhs-oxadiaz-bala-betahb 1175:bhs-nme35pyr-gly-betaanaphth 1176.phhs-25thiaz-bala-psdapch 1177:tolhs-oxadiaz-bala-betahmo 1178:tolhs-25methiaz-bala-betathio3 1179:bim-25oxaz-ala-psdap 1180:bim-42nmeim-gly-betapy 1181:ibhs-nme35pyr-bala-betah35dc 1182:tolhs-24thioph-gly-betabthioph WO 00166618 PCTlEP00103469 1183: tolhs-25methiaz-bala-betadito 1184: thpym-25thiaz-bala-psdap 1185: bhs-25oxaz-gly-zdap 1186: bhs-25thiaz-phe-betameph 1187: bhs-25methiaz~ly-betathiobe 1188: bhs-nme35pyr-bala-betameph 1189: phhs-ithiadiaz-gly-betaoxope 1190: tolhs-24thiaz-gly-betabpy 1191: phhs-ithiadiaz-bala-psdap 1192:bgua-42nmeim-gly-betadcph 1193: dhim-24oxaz-gly-betamyl 1194: impy-25oxaz-gly-betampy 1195: bhs-25methiaz-bala-betadmoph 1196: gua-24thiaz-gly-betadito 1197:ibhs-ithiadiaz-gly-busu2be 1198: bhs-oxadiaz-bala-betadito 1199: ibhs-24thiaz-bala-betaphethioa 1200: ibhs-ithiadiaz-bala-betatrif 1201: bhs-24thioph-ala-psdap 1202:ibhs-nme35pyr-bala-betahdbph 1203: bhs-24thioph-bala-psdap 1204: 2py-25thiaz-gly-betatbuph 1205: ibhs-24thioph-bala-beta3quin 1206: ibhs-ithiadiaz-bala-betaoxaz 1207:bhs-me24oxaz-gly-zdap 1208: gua-24thiaz-gly-betah35dc 1209: ibhs-24thioph-gly-betatrif 1210: tolhs-25methiaz-gly-betambiph 1211: thpym-26py-gly-betadcph 1212:phhs-24thioph-bala-betahmph 1213: ibhs-25methiaz-bala-betadmph 1214: tolhs-24thioph-gly-betafphe 1215; tolhs-25oxaz-bala-betabnaphth 1216: bhs-24thioph-gly-betaoxope 1217:pahs-26py-gly-betapy 1218: 2py-24im-gly-betadcph 1219: tolhs-nme35pyr-bala-betapytb 1220: phhs-nme35pyr-gly-betapyee 1221: bhs-25thiaz-bala-betabmph 1222: gua-42pym-gly-betadmoph 1223: ibhs-nme35pyr-bala-betathiome 1224: ibhs-25methiaz-gly-betainyl 1225: bhs-24thiaz-gly-betahcbph 1226: ibhs-24thiaz-bala-psdap 1227: bhs-triaz-ala-zdap 1228. dhim-24thiaz-ala-betameph 1229:ibhs-24thiaz-bala-betapych 1230: ibhs-25methiaz-gly-betaoxope 1231: tolhs-24thiaz-bala-betahbcph 1232: tolhs-24thioph-giy-betathio3 1233: tolhs-oxadiaz-gly-betapych 1234:tolhs-24thiaz-bala-betatbuph 1235: 2py-25oxaz-leu-betadcph 1236: ibhs-24thiaz-gly-betadito 1237: tolhs-25thiaz-bala-betacthioph 1238: phhs-24thiaz-bala-betaimid 1239:ibhs-25methiaz-gly-betabnaphth 1240: dhim-24oxaz-ala-betameph 1241: phhs-oxadiaz-gly-beta34meoph 1242: 2py-oxadiaz-bala-asppha 1243: phhs-nme35pyr-gly-aspibua 1244:ibhs-nme35pyr-gly-beta13bendi 1245: bhs-oxadiaz-gly-betahb 1246: tolhs-24thioph-gly-beta4bph 1247: ibhs-25oxaz-bala-betah35dc 1248: ibhs-25thiaz-gly-betaoxope 1249:thpym-25thioph-gly-betahcbph 1250: tolhs-25oxaz-bala-betahmofu 1251: bhs-42pym-ala-psdap 1252: bhs-24thiaz-nmgly-betaipro 1253: ibhs-nme35pyr-gly-betahmofu 1254:phhs-ithiadiaz-gly-betapym 1255: ibhs-24thioph-bala-betahbcph 1256: tolhs-oxadiaz-bala-betadcphch WO 00166618 PCTlEP00103469 1257:phhs-24thioph-bala-betabmph 1258:phhs-25oxaz-bala-betaftrif 1259:2py-thiadiaz-ala-betadcph 1260:phhs-me25thiaz-leu-psdap 1261:phhs-nme35pyr-gly-betapych 1262:bhs-oxadiaz-bala-betafu3 1263:2pmhs-42nmeim-bala-betameph 1264:ibhs-oxadiaz-bala-betabmph 1265:ibhs-25thiaz-bala-beta23meoph 1266:gua-25thiaz-giy-betaph 1267:bhs-24thiaz-ser-betapy 1268:bhs-24thiaz-met-betadcph 1269:bhs-ithiadiaz-gly-betacthioph 1270:bhs-42pym-gly-betainyl 1271:2py-triaz-bala-zdap 1272:2py-me24oxaz-ala-zdap 1273:phhs-24thioph-bala-betahc 1274:tolhs-24thioph-bala-psdapch 1275:phhs-oxadiaz-gly-betainyl 1276:bhs-25thiaz-nmgly-betamesu 1277:ibhs-24thioph-bala-beta34dcph 1278:phhs-nme35pyr-bala-betameph 1279:phhs-24thioph-bala-betaamibe 1280:2py-oxadiaz-leu-psdap 1281;bim-25thiaz-ala-betadcph 1282:bim-35thioph-gly-zdap 1283:bim-35py-gly-zdap 1284:ibhs-25oxaz-bala-betapyee 1285:tolhs-me24thiaz-bala-zdap 1286:tolhs-25thiaz-bala-betadito 1287:phhs-oxadiaz-gly-betadtrif 1288:bhs-24thioph-gly-betathiobe 1289:bhs-25thiaz-gly-betaphethioa 1290:tolhs-25oxaz-gly-betahc 1291:bhs-25oxaz-gly-betaimid 1292:tolhs-oxadiaz-bala-betaipr 1293:phhs-24thiaz-gly-betapyr WO 00/66618 PCTIEPOOl03469 1294:bhs-me25thioph-gly-betadcph 1295:phhs-nme35pyr-bala-betadmoph 1296:phhs-24thioph-bala-betabpy 1297:phhs-24thioph-bala-beta23meoph 1298:phhs-24thiaz-bala-zdapch 1299:bhs-42oxaz-bala-zdap 1300:ibhs-ithiadiaz-bala-betadcphee 1301;phhs-nme35pyr-bala-betambiph 1302:bim-42nmeim-bala-betacbph 1303:tolhs-25thiaz-bala-beta34dcph 1304:hs-25methiaz-bala-betapy 1305:dhim-4.2pym-gly-betapy 1306:bhs-42oxaz-leu-betapy 1307:bhs-24thiaz-nmgly-betadmph 1308:dhim-25thiaz-ala-psdap 1309:phhs-25oxaz-bala-betamethi 1310:phhs-me24thiaz-ala-betaph 1311:ibhs-24thioph-gly-betameph 1312:gua-24oxaz-gly-betaheph 1313:bhs-ithiadiaz-gly-betal3bendi 1314:bhs-ithiadiaz-bala-betahcbph 1315:bhs-nme35pyr-gly-betaheph 1316:bhs-25thiaz-1eu-psdap 1317:tolhs-25oxaz-bala-betadmoph 1318:bim-25thiophme-gly-zdap 1319:bhs-nme35pyr-nmgly-betabnaphth 1320:2py-24thioph-bala-betahni 1321:phhs-oxadiaz-bala-psdapch 1322:ibhs-25thiaz-bala-betabediox 1323:tolhs-25oxaz-gly-betafphe 1324:ibhs-25methiaz-bala-beta4bph 1325:tolhs-25thiaz-gly-betadbph 1326:dhim-26py-gly-zdap 1327:ibhs-24thioph-gly-betacthioph 1328:2py-ithiadiaz-gly-psdap 1329:tolhs-me25oxaz-ala-betaph 1330:ibhs-nme35pyr-gly-betamethioph 1331:bhs-ithiadiaz-bala-betabpy 1332:bhs-oxadiaz-bala-betabph 1333:ibhs-oxadiaz-gly-betampy 1334:dhthi-26py-gly-betapy 1335:bhs-25thiaz-gly-betadmph 1336:bim-25methiaz-gly-betaomebendi 1337:tolhs-25thiaz-bala-betadhbfu 1338:bhs-oxadiaz-nmgly-beta34meoph 1339:bim-nme35pyr-bala-asppha 1340:2py-42nmeim-gly-betafphe 1341:bhs-35thioph-gly-psdap 1342:2py-42nmeim-bala-betaanaphth 1343:phhs-25thiaz-gly-psdapch 1344:bhs-25methiaz-bala-betabdimo 1345:tolhs-me24oxaz-gly-betaph 1346:ibhs-24thioph-bala-betadito 1347:bhs-24thioph-nmgly-betabnaphth 1348:bhs-oxadiaz-bala-betadcphtb 1349:bhs-26py-ala-psdap 1350:bhs-24thioph-nmgly-betamesu 1351:tolhs-oxadiaz-bala-betaimid 1352:bhs-ithiadiaz-nmgly-betadito 1353:phhs-25methiaz-bala-zdapee 1354:bhs-ithiadiaz-bala-betaphethioa 1355:impy-24thioph-gly-betambiph 1356:bhs-ithiadiaz-gly-betafu2 1357:bhs-ithiadiaz-nmgly-betathioph 1358:phhs-25oxaz-bala-suabu 1359:bhs-25methiaz-bala-betacbph 1360:phhs-me24oxaz-bala-betadcph 1361:dhim-25thiaz-gly-betadtrif 1362:bhs-24thioph-bala-betathiome 1363:phhs-25oxaz-gly-beta34dcph 1364:tolhs-me25oxaz-bala-betadcph 1365:ibhs-25thiaz-gly-betaamibe 1366:bhs-nme35pyr-nmgly-beta23meoph 1367:2py-24thiaz-gly-aspaba WO 00166fi18 PCTIEP00103469 1368:gua-24thioph-bala-betadcph 1369:tolhs-24thioph-gly-betamethioph 1370:gua-24thiaz-gly-betaph 1371:2py-25methiaz-bala-aspibua 1372:ibhs-25oxaz-gly-zdaptb 1373:phhs-me25thiaz-leu-betadcph 1374:bhs-nme35pyr-bala-psdaptb 1375:bhs-25methiaz-gly-betahcbph 1376:ibhs-25methiaz-gly-betah35dc 1377:bhs-24thiaz-bala-aspaba 1378:tolhs-ithiadiaz-bala-beta13bendi 1379:bhs-ithiadiaz-bala-betaph 1380:tolhs-oxadiaz-gly-betaoxope 1381:2py-thiadiaz-gly-betapy 1382:phhs-24thiaz-bala-betaphethioa 1383:gua-24thiaz-gly-beta35dbph 1384:bim-26py-gly-betainyl 1385:pahs-25thiaz-bala-betameph 1386:bim-thiadiaz-ala-psdap 1387:bhs-me24thiaz-leu-beta34meoph 1388:phhs-25oxaz-gly-betambiph 1389:phhs-oxadiaz-gly-betaomebendi 1390:phhs-25oxaz-bala-betamethioph 1391:dhim-24thiaz-gly-betapy 1392:bim-24thioph-nmala-betadcph 1393:bhs-nme35pyr-gly-betampy 1394:2py-me24oxaz-ba la-betapy 1395:2py-25thioph-gly-zdap 1396:ibhs-24thioph-bala-betah35dc 1397:phhs-me25thioph-gly-betadcph 1398:bhs-24thioph-bala-betapym 1399:tolhs-24thioph-gly-aspbzla 1400:ibhs-25thiaz-bala-betapyee 1401:tolhs-nme35pyr-gly-betapyee 1402:bhs-25oxaz-gly-betahdcph 1403:bhs-25oxaz-gly-beta4bph 1404:ibhs-24thiaz-bala-beta4bph WO 00166fi18 PCTlEP001034fi9 1405:bim-ithiadiaz-bala-betapy 1406:ibhs-nme35pyr-bala-betabdimo 1407:2py-25thiaz-gly-aspibua 1408:bhs-25oxaz-ala-betabpy 1409:bhs-oxadiaz-gly-betahbcph 1410:bim-me25thioph-leu-betaph 1411:bhs-24thiaz-bala-betadito 1412:dhim-24oxaz-gly-betadcph 1413:tolhs-ithiadiaz-gly-betahcbph 1414:bhs-nme35pyr-leu-betapy 1415:tolhs-nme35pyr-bala-betaol 1416:ibhs-oxadiaz-gly-betapych 1417:tolhs-nme35pyr-gly-betacthioph 1418:tolhs-nme35pyr-bala-aspbzla 1419:2py-me24thioph-gly-beta34meoph 1420:dhpyrr-24thiaz-gly-betadcph 1421:bhs-24thiaz-gly-betaet 1422:bim-24thiaz-nmala-betadcph 1423:ibhs-nme35pyr-gly-betambiph 1424:tolhs-ithiadiaz-gly-ibsdap 1425:tolhs-25oxaz-gly-betacthioph 1426:tolhs-24thioph-gly-betadhbfu 1427:bhs-me25thiaz-ala-betaph 1428:phhs-25thiaz-bala-betameph 1429:bhs-24thiaz-ala-beta34dcph 1430:ibhs-nme35pyr-bala-betapyr 1431:2py-me24thioph-leu-betapy 1432:bhs-24thiaz-bala-betafu2 1433:bhs-ithiadiaz-bala-betaamibe 1434:bhs-25methiaz-ala-betadmoph 1435:bim-me24thiaz-gly-zdap 1436:bim-25methiaz-bala-csdap 1437:2py-me25oxaz-ala-beta34meoph 1438;phhs-oxadiaz-gly-ibsdap 1439:phhs-25thiaz-bala-betabph 1440:bhs-25methiaz-ala-beta34dcph 1441:tolhs-oxadiaz-bala-betapyee WO 00166618 PCTlEP00103469 1442:ibhs-oxadiaz-bala-betaanaphth 1443:tolhs-25oxaz-bala-betathiobe 1444:2pmhs-24thiaz-bala-beta4bph 1445:ibhs-ithiadiaz-gly-ibsdap 1446:phhs-24thioph-bala-aspaba 1447:tolhs-24thiaz-bala-betaamibe 1448:bhs-25methiaz-gly-betaanaphth 1449:bhs-24thioph-gly-betaph 1450:bhs-oxadiaz-bala-betahb 1451:bhs-52thiaz-gly-betapy 1452:ibhs-oxadiaz-bala-betafluo 1453:phhs-nrne35pyr-bala-betadtrif 1454:phhs-25oxaz-bala-betapyr 1455:bhs-25methiaz-bala-betaipr 1456:ibhs-24thiaz-gly-beta35dbph 1457:ibhs-25thiaz-gly-psdapch 1458:bhs-24thiaz-bala-betatbuph 1459:tolhs-ithiadiaz-bala-betadmoph 1460:ibhs-25thiaz-gly-betaftrif 1461:bhs-25methiaz-ala-betafphe 1462:sabhs-42pym-gly-betapy 1463:phhs-me25thiaz-bala-zdap 1464:phhs-24thiaz-gly-betaibph 1465:2py-25methiaz-gly-betacthioph 1466:dhim-25thioph-gly-betapy 1467:bim-me24thiaz-bala-psdap 1468:ibhs-24thioph-gly-betabnaphth 1469:tolhs-25methiaz-bala-betaoxope 1470:sabhs-25oxaz-bala-betameph 1471:tolhs-25methiaz-gly-beta34dcph 1472:ibhs-oxadiaz-bala-betathiome 1473:dhim-42pym-gly-betahdcph 1474:2py-25thiaz-leu-betapy 1475:ibhs-25thiaz-gly-betah35dc 1476:bhs-25oxaz-bala-betathiobe 1477:bhs-oxadiaz-nmgly-betamesu 1478:bhs-oxadiaz-bala-betaol WO 00!66618 PCTlEP00103469 1479:phhs-oxadiaz-gly-aspbzla 1480:hs-25thiaz-gly-betapy 1481:tolhs-ithiadiaz-bala-betaomebendi 1482:tolhs-25methiaz-bala-beta4bph 1483:phhs-ithiadiaz-bala-csdap 1484:bim-25py-gly-zdap 1485:ibhs-24thioph-gly-betafbph 1486:impy-25methiaz-gly-betambiph 1487:2pmhs-25thiaz-bala-betamethioph 1488:tolhs-24thioph-bala-betafluo 1489:ibhs-ithiadiaz-gly-aspaba 1490;phhs-25methiaz-bala-betacph 1491:bhs-nme35pyr-gly-betatos 1492:dimethpym-25thiaz-gly-betadcph 1493:ibhs-oxadiaz-bala-betaimid 1494:tolhs-24thioph-bala-betaoxope 1495:bhs-nme35pyr-bala-betamethioph 1496:2py-me24thiaz-leu-betaph 1497:tolhs-nme35pyr-bala-betahni 1498:phhs~xadiaz-gly-betacthioph 1499:bhs-25thiaz-gly-busu2be 1500:ibhs-oxadiaz-bala-betaipro 1501:tolhs-25thiaz-bala-betadmoph 1502:bhs-25methiaz-ala-betainyl 1503:bhs-25oxaz-bala-betahcbph 1504:ibhs-ithiadiaz-gly-betacthioph 1505:tolhs-nme35pyr-bala-betaomebendi 1506:phhs-24thioph-bala-betaipr 1507;tolhs-25methiaz-gly-betaoxaz 1508:tolhs-nme35pyr-bala-betaamibe 1509:bhs-25thiaz-bala-betaheph 1510:ibhs-24thioph-gly-asppha 1511:phhs-oxadiaz-bala-betadmoph 1512:2py-25thiaz-ala-betameph 1513:bhs-thiadiaz-ala-zdap 1514:bhs-24thiaz-bala-betafph 1515:2pmhs-25thiaz-bala-betabmph WO 00166618 PCTlEPOOI03469 1516:bhs-24thioph-bala-betafu2 1517:bim-me25thioph-bala-zdap 1518:bhs-25methiaz-gly-aspibua 1519:bhs-nme35pyr-nmgly-beta34dcph 1520:gua-24thiaz-gly-betafu2 1521:phhs-oxadiaz-gly-betambiph 1522:bhs-24thioph-bala-aspaba 1523:phhs-24thiaz-gly-beta35dbph 1524:ibhs-24thioph-gly-betaipro 1525:bhs-ithiadiaz-bala-psdapch 1526:bhs-25oxaz-gly-betamethioph 1527:bhs-25thiaz-ala-beta34dcph 1528:bhs-ithiadiaz-bala-betaipro 1529:bhs-25oxaz-gly-betah35dc 1530:gua-25thioph-gly-betah35dc 1531:bhs-25oxaz-gly-betabph 1532:bhs-oxadiaz-bala-betaphethio 1533:impy-24thiaz-bala-psdap 1534:bhs-25methiaz-gly-betaol 1535:phhs-25oxaz-bala-betapytb 1536:tolhs-25oxaz-bala-zdaptb 1537:tolhs-nme35pyr-bala-betadcphee 1538:bgua-25thioph-gly-betameph 1539:bhs-oxadiaz-gly-betathio3 1540:ibhs-25thiaz-gly-betahc 1541:gua-24thiaz-gly-betathioph 1542:2py-53pyrazo-bala-betapy 1543:phhs-ithiadiaz-gly-beta34dcph 1544:dhim-25thioph-ala-betadcph 1545:phhs-25thiaz-gly-betapy 1546:ibhs-25thiaz-bala-betah35dc 1547:phhs-25methiaz-gly-psdap 1548:bhs-oxadiaz-gly-betafluo 1549:impy-25thiaz-gly-betacbph 1550:2py-24im-bala-zdap 1551:tolhs-oxadiaz-bala-betahb 1552:phhs-25oxaz-bala-betaoxope WO OOI66618 PCTlEP00103469 1553:tolhs-25thiaz-gly-betaipr 1554:ibhs-oxadiaz-bala-csdap 1555:ibhs-24thiaz-gly-betampy 1556:bim-thiadiaz-gly-betadcph 1557:2py-me24thioph-bala-betadcph 1558:bhs-ithiadiaz-nmgly-betadhbfu 1559:phhs-25oxaz-bala-betathioph 1560:ibhs-25oxaz-bala-betaol 1561:bhs-nme35pyr-gly-betaoxope 101562:phhs-ithiadiaz-bala-betathiobe 1563:2py-25methiaz-leu-zdap 1564:tolhs-25thiaz-gly-betafu2 1565:phhs-24thioph-bala-betahni 1566;ibhs-nme35pyr-gly-betatbuph 151567:ibhs-ithiadiaz-gly-betapbiph 1568:tolhs-oxadiaz-gly-betatos 1569:bim-triaz-bala-betapy 1570:tolhs-25oxaz-bala-betafphe 1571:bhs-ithiadiaz-nmgly-betathio3 201572:2py-me25thioph-gly-zdap 1573:tolhs-25oxaz-gly-csdap 1574:2py-thiadiaz-gly-psdap 1575:bhs-52thiaz-gly-betainyl 1576:phhs-ithiadiaz-gly-betahmo 251577:ibhs-25thiaz-gly-betathiome 1578:2py-oxadiaz-bala-betapy 1579:2pmhs-24thiaz-bala-betathioph 1580:bim-25thiaz-bala-betahc 1581;bim-triaz-leu-psdap 301582:phhs-25methiaz-bala-aspibua 1583:bhs-me24thioph-bala-beta34meoph 1584:phhs-25oxaz-gly-betadcphtb 1585:tolhs-ithiadiaz-gly-beta4bph 1586:ibhs-25oxaz-bala-betamethioph 351587:phhs-ithiadiaz-gly-betah35dc 1588;bhs-25methiaz-gly-betahdbph 1589:gua-25thiaz-gly-betahdbph 1590:4pmhs-24thiaz-bala-betameph 1591:bhs-ithiadiaz-gly-betainyl 1592:tolhs-25oxaz-bala-betah35dc 1593:2py-25fur-bala-psdap 1594:nmhs-24thiaz-gly-psdap 1595:phhs-25methiaz-bala-betadcphee 1596:ibhs-25methiaz-bala-betabph 1597:ibhs-oxadiaz-bala-betabph 1598:ibhs-ithiadiaz-bala-betahbcph 1599:2py-triaz-ala-zdap 1600:bhs-nme35pyr-nmgly-beta3quin 1601:dhim-25thioph-ala-zdap 1602:bhs-me24oxaz-leu-beta34meoph 1603:phhs-25methiaz-gly-aspaba 1604:bhs-nme35pyr-bala-betadtrif 1605:tolhs-24thioph-bala-betadtrif 1606:bhs-25methiaz-bala-betahb 1607:2py-24thiaz-ala-betainyl 1608:bhs-25thiaz-gly-betaph 1609:tolhs-oxadiaz-bala-betabediox 1610:bhs-oxadiaz-bala-betaoxope 1611:bhs-25thiaz-nmgly-betaanaphth 1612:phhs-24thioph-gly-betadmph 1613:phhs-25methiaz-gly-betainyl 1614:gua-24thiaz-gly-betadcph 1615:bhs-24thioph-bala-betadcphee 1616:phhs-ithiadiaz-gly-betabph 1617:bhs-thiadiaz-ala-betapy 1618:bim-me25oxaz-leu-psdap 1619:2py-me24thioph-bala-betaph 1620:tolhs-nme35pyr-bala-betabediox 1621:bhs-25methiaz-ala-beta34meoph 1622:tolhs-ithiadiaz-gly-betadmoph 1623:bhs-24thiaz-nmala-betapy 1624:2py-triaz-leu-betadcph 1625:ibhs-24thioph-bala-betaibph 1626:phhs-me25oxaz-ala-betaph 1627:gua-24oxaz-gly-betaph 1628:phhs-ithiadiaz-gly-betapych 1629:bhs-me24oxaz-leu-zdap 1630:ibhs-25thiaz-bala-betamethi 1631:bim-42oxaz-leu-psdap 1632:bhs-25thiaz-hphe-betameph 1633:bhs-nme35pyr-nmgly-betabpy 1634:2pmhs-25thiaz-bala-beta13bendi 1635:ibhs-ithiadiaz-gly-zdapch 1636:tolhs-oxadiaz~ly-psdapee 1637:bhs-25oxaz-ala-betainyl 1638:tolhs-25thiaz-bala-suabu 1639:bim-24thiaz-leu-betadcph 1640:bhs-24thioph-gly-beta34dcph 1641:tolhs-oxadiaz-gly-aspaba 1642:phhs-25thiaz-gly-betathiome 1643:phhs-24thioph-bala-psdaptb 1644:phhs-nme35pyr-bala-betabediox 1645:tolhs-oxadiaz-gly-betahcbph 1646:bhs-ithiadiaz-bala-betaomebendi 1647:phhs-24thioph-bala-betahph 1648:2py-me25thioph-ala-psdap 1649:2py-24thiaz-leu-betapy 1650:2py-25oxaz-gly-aspibua 1651:sabhs-24thiaz-gly-betapy 1652:phhs-25oxaz-gly-betahbcph 1653:tolhs-25methiaz-bala-betabph 1654:bhs-ithiadiaz-bala-aspibua 1655:dhim-26py-gly-betaoxaz 1656:ibhs-oxadiaz-gly-beta4bph 1657:bhs-24thiaz-nmgly-beta3quin 1658:phhs-25methiaz-gly-betabph 1659:tolhs-25methiaz-gly-betathiobe 1660:bhs-25thiaz-bala-zdapee 1661:bim-24thiaz-bala-zdap 1662:2pmhs-42nmeim-ser-psdap 1663:phhs-24thiaz-gly-betathio3 WO 00!66618 PCTIEP00103469 1664:bhs-24thioph-nmgly-beta13bendi 1665:phhs-25methiaz-gly-betaheph 1666:tolhs-25thiaz-gly-betaet 1667:tolhs-me24thioph-ala-betadcph 1668:ibhs-25oxaz-bala-betaipr 1669:phhs-me25thioph-ala-zdap 1670:ibhs-25thiaz-bala-betambiph 1671:tolhs-me25thioph-ala-beta34meoph 1672:ibhs-25thiaz-gly-betaphethio 1673:phhs-24thiaz-bala-betaomebendi 1674:ibhs-24thiaz-gly-beta34meoph 1675:bim-35fu~-bala-betapy 1676:tolhs-25thiaz-gly-zdapee 1677:ibhs-25oxaz-gly-betatrif 1678:phhs-oxadiaz-gly-betamethioph 1679:2py-thiadiaz-bafa-zdap 1680:bhs-24thioph-bala-zdapch 1681:bhs-25methiaz-bala-betafu2 1682:ibhs-oxadiaz-gly-psdap 1683:bhs-oxadiaz-gly-betapyee 1684:bhs-me24thioph-gly-zdap 1685:bim-me25oxaz-ala-zdap 1686:bhs-25methiaz-gly-betaomebendi 1687:tolhs-25thiaz-bala-betahb 1688:2py-24thioph-bala-beta34dcph 1689:ibhs-oxadiaz-bala-betapych 1690:ibhs-24thioph-gly-betafu2 1691:bhs-25oxaz-ala-beta3quin 1692:bhs-24thioph-bala-betabediox 1693:phhs-nme35pyr-gly-betapy 1694:ibhs-ithiadiaz-gly-betamesu 1695:bhs-25methiaz-gly-betabediox 1696:phhs-25thiaz-gly-betafu2 1697:2py-24thiaz-bala-betaheph 1698:phhs-oxadiaz-gly-asppha 1699:ibhs-ithiadiaz-bala-psdap 1700:thpym-25methiaz-bala-psdap WO 00166618 PCTlEP00103469 1701:tolhs-25oxaz-bala-betabenfu 1702:ibhs-ithiadiaz-gly-betathio3 1703:bhs-25methiaz-gly-betampy 1704:bim-52thiaz-gly-betameph 1705:tolhs-nme35pyr-gly-beta23meoph 1706:bhs-ithiadiaz-bala-betaftrif 1707:bhs-25oxaz-gly-betadmoph 1708:phhs-24thiaz-gly-betainyl 1709:ibhs-25thiaz-gly-betaanaphth 1710:phhs-ithiadiaz-bala-betaphethio 1711:phhs-25thiaz-bala-betahdcph 1712:4pmhs-25oxaz-gly-betapy 1713:bhs-53pyrazo-ala-betapy 1714:phhs-nme35pyr-bala-betathioph 1715:bhs-nme35pyr-nmgly-betamesu 1716:phhs-25oxaz~ly-betampy 1717:2py-25oxaz-ba la-betapheth ioa 1718:bhs-25methiaz-bala-betafu3 1719:phhs-me24oxaz-leu-betadcph 1720:bhs-25thiaz-ala-ibsdap 1721:bhs-ithiadiaz-gly-betabmph 1722:bhs-ithiadiaz-bala-betadmoph 1723:phhs-25thiaz-gly-betatbuph 1724:2py-42pym-ala-psdap 1725:ibhs-nme35pyr-gly-betaoxaz 1726:phhs-24thioph-bala-betafu3 1727:phhs-25oxaz-bala-betapbiph 1728:2py-me25oxaz-ala-betapy 1729:phhs-me24thiaz-gly-betaph 1730:bhs-25methiaz-nmgly-betaipro 1731:phhs-me24thiaz-leu-psdap 1732:gua-42pym-gly-betaphethio 1733:bhs-24thioph-gly-betaoxaz 1734:bhs-oxadiaz-bala-betahc 1735:ibhs-nme35pyr-gly-betainyl 1736:tolhs-nme35pyr-bala-psdaptb 1737:bhs-oxadiaz-bala-betadmph WO 00!66618 PCTIEP00103469 1738:phhs-ithiadiaz-gly-betafbph 1739:phhs-25thiaz-gly-betahcbph 1740:tolhs-25oxaz-bala-betaibph 1741:tolhs-25oxaz-gly-betapych 1742:bhs-24thiaz-nmgly-betabnaphth 1743:phhs-25methiaz-gly-zdap 1744:2py-42nmeim-gly-betaipro 1745:bhs-24thioph-bala-betafph 1746:ibhs-24thioph-bala-betambiph 1747:2pmhs-42nmeim-gly-betahdcph 1748:2py-24thiaz-gly-zdap 1749:phhs-oxadiaz-bala-betamethi 1750:bhs-me25thiaz-bala-betaph 1751:bhs-triaz-ala-betadcph 1752:bhs-25methiaz-bala-betahmofu 1753:bhs-25thiaz-ala-betafphe 1754:phhs-oxadiaz-bala-betafluo 1755:phhs-24thiaz-bala-betabenfu 1756:2py-24thiaz-bala-aspbzla 1757:bhs-24thiaz-ala-psdap 1758:phhs-oxadiaz-gly-betapyee 1759:tolhs-25thiaz-bala-betaph 1760:ibhs-24thioph-bala-betaheph 1761:tolhs-24thioph-bala-zdaptb 1762:tolhs-24thiaz-gly-zdapee 1763:ibhs-ithiadiaz-bala-betaomebendi 1764:phhs-ithiadiaz-bala-betamethioph 1765:phhs-nme35pyr-bala-betathiobe 1766:phhs-25thiaz-bala-betafphe 1767:ibhs-25thiaz-bala-beta34dcph 1768:phhs-24thiaz-gly-psdaptb 1769:tolhs-24thioph-gly-betatos 1770:gua-26py-gly-betamethi 1771:bhs-oxadiaz-gly-betahmofu 1772:impy-4.2nmeim-gly-betahph 1773:bhs-24thiaz-bala-betadcphtb 1774:tolhs-ithiadiaz-gly-busu2be 1775:bim-me24oxaz-bala-beta34meoph 1776.tolhs-25methiaz-gly-betafu3 1777:tolhs-25oxaz-bala-aspbzla 1778:bhs-oxadiaz-ala-betacph 1779:phhs-ithiadiaz-bala-aspbzla 1780:ibhs-25thiaz-bala-betaph 1781:tolhs-oxadiaz-bala-csdap 1782:ibhs-oxadiaz-gly-betadtrif 1783:ibhs-25thiaz-gly-betadito 1784:tolhs-25oxaz-bala-suabu 1785:bhs-ithiadiaz-bala-zdap 1786:bhs-25thioph-gly-psdap 1787:2py-24im-ala-zdap 1788:2pmhs-25methiaz-gly-betaph 1789:phhs-25oxaz-gly-psdap 1790:bhs-24thioph-bala-betabenfu 1791:bim-me25oxaz-gly-betadcph 1792:bhs-oxadiaz-bala-betahmph 1793:ibhs-ithiadiaz-bala-betafph 1794:ibhs-25oxaz-bala-betacph 1795:ibhs-25methiaz-gly-betaipro 1796:ibhs-24thiaz-gly-betabph 1797:2py-triaz-leu-betapy 1798:tolhs-nme35pyr-gly-zdapch 1799:bhs-thiadiaz-leu-betadcph 1800:tolhs-ithiadiaz-bala-beta34dcph 1801:phhs-25oxaz-bala-betampy 1802:tolhs-nme35pyr-gly-betabediox 1803:phhs-24thiaz-gly-betabenfu 1804:ibhs-24thioph-gly-betaanaphth 1805:ibhs-24thiaz-bala-betabthioph 1806:bhs-24thiaz-gly-betameph 1807:bhs-24thioph-bala-betaph 1808:ur-25oxaz-bala-zdap 1809:phhs-25thiaz-gly-betadcph 1810:ibhs-24thiaz-gly-betaphethio 1811:agua-24thioph-gly-psdap 1812: tolhs-24thiaz-bala-betadmoph 1813: phhs-nme35pyr-gly-betaheph 1814: bhs-ithiadiaz-gly-aspbzla 1815: cima-25methiaz-bala-psdap 1816: bim-25thiaz-bala-aspaba 1817: phhs-oxadiaz-bala-betahcbph 1818: phhs-me24thiaz-ala-betadcph 1819: bim-25oxaz-gly-betafph 1820: bhs-25methiaz-gly-betabenfu 1821:gua-42pym-gly-betabph 1822: bim-24thioph-bala-asppha 1823: ibhs-oxadiaz-bala-betamethi 1824: tolhs-24thiaz-bala-betabediox 1825: tolhs-25oxaz-bala-psdap 1826:ibhs-25thiaz-bala-beta35dbph 1827: ibhs-25oxaz-gly-betamesu 1828: ibhs-24thioph-gly-betambiph 1829: bhs-25oxaz-gly-betahcbph 1830: ibhs-24thioph-gly-betahc 1831:2py-25methiaz-gly-asppha 1832: phhs-oxadiaz-gly-betacbph 1833: ibhs-ithiadiaz-bala-betaipro 1834: bhs-25thiaz-ala-betacthioph 1835: phhs-25thiaz-gly-aspibua 1836:ibhs-25methiaz-bala-betamesu 1837: bim-42nmeim-bala-betabediox 1838: tolhs-me25thioph-gly-betadcph 1839: ibhs-25methiaz-bala-betafbph 1840: phhs-25oxaz-gly-beta35dbph 1841:phhs-24thioph-bala-betaet 1842: ibhs-25oxaz-gly-betadcphee 1843: phhs-25oxaz-gly-betadtrif 1844: hs-42nmeim-bala-zdap 1845: bim-25methiaz-gly-betaibph 1846:bim-thiadiaz-ala-betapy 1847: 2py-me24im-ala-betapy 1848: bhs-24thiaz-gly-betamethioph 1849:tolhs-24thiaz-gly-beta23meoph 1850:tolhs-nme35pyr-bala-zdaptb 1851:ibhs-nme35pyr-gly-betah35dc 1852:bhs-25thiaz-gly-betahph 1853:bhs-25thiaz-bala-betatbuph 1854:ur-24thioph-gly-betadcph 1855:tolhs-me25thiaz-gly-psdap 1856:ibhs-24thiaz-gly-betafu2 1857:bhs-ithiadiaz-gly-betathiobe 1858:bim-25fur-bala-betapy 1859:phhs-25thiaz-gly-betahmph 1860:tolhs-nme35pyr-bala-betadbph 1861:ibhs-oxadiaz-bala-betamesu 1862:ibhs-25oxaz-bala-betabediox 1863:tolhs-oxadiaz-bala-betabnaphth 1864:bhs-oxadiaz-bala-zdapee 1865:ibhs-24thiaz-bala-betafph 1866:tolhs-25methiaz-bala-betaibph 1867:bhs-24thioph-gly-betatrif 1868:3pmhs-42nmeim-bala-zdap 1869:phhs-nme35pyr-gly-betathioph 1870:tolhs-nme35pyr-bala-busu2be 1871:bhs-24thiaz-gly-betaoxope 1872:tolhs-24thiaz-gly-betatrif 1873:bhs-25methiaz-gly-betahmo 1874:tolhs-oxadiaz-gly-betahph 1875:phhs-ithiadiaz-gly-zdaptb 1876:bim-42nmeim-bala-betahmofu 1877:2py-thiadiaz-gly-zdap 1878:bhs-ithiadiaz-gly-betahmo 1879:bim-25thiaz-gly-aspibua 1880:bhs-nme35pyr-gly-betapy 1881:bhs-ithiadiaz-ala-betapy 1882:ibhs-nme35pyr-bala-betafphe 1883:bhs-53pyrazo-bala-betadcph 1884:ibhs-25methiaz-gly-betahcbph 1885:tolhs-25methiaz-gly-betaphethio WO 00166618 PCTI~P00103469 1886:bhs-24thiaz-bala-beta23meoph 1887:ibhs-nme35pyr-gly-zdap 1888:bhs-25thiaz-gly-betadcphtb 1889:gua-26py-gly-betacbph 1890:2py-25th iaz-g ly-betath io3 1891:tolhs-24thioph-bala-betapyee 1892:bhs-oxadiaz-gly-betaoxaz 1893:ibhs-25thiaz-bala-betahdbph 1894:ibhs-ithiadiaz-bala-betaheph 1895:ibhs-24thiaz-gly-betahmofu 1896:tolhs-24thioph-bala-betaoxaz 1897:phhs-25methiaz-gly-betapbiph 1898:tolhs-24thiaz-gly-betamethi 1899:tolhs-24thiaz-bala-betamethioph 1900:bhs-ithiadiaz-bala-betapyee 1901:bhs-25thiaz-bala-zdaptb 1902:ibhs-nme35pyr-bala-beta34meoph 1903:tolhs-me25thioph-ala-zdap 1904:ibhs-25methiaz-gly-betaamibe 1905:phhs-25oxaz-bala-betabdimo 1906:2py-triaz-gly-betapy 1907:ibhs-25oxaz-bala-betadcphch 1908:bhs-oxadiaz-nmgly-betadmph 1909:bhs-24thiaz-bala-beta35dbph 1910:tolhs-24thioph-gly-betapy 1911:gua-26py-gly-betacthioph 1912:bhs-25oxaz-bala-betapy 1913:dhpyrr-25thiaz-gly-betapy 1914:tolhs-24thioph-bala-betapym 1915:ibhs-24thioph-bala-betapbiph 1916:gua-26py-gly-betaipro 1917:bim-oxadiaz-bala-aspibua 1918:tolhs-nme35pyr-bala-betadtrif 1919:tolhs-25thiaz-gly-betafluo 1920:phhs-oxadiaz-bala-beta23meoph 1921:tolhs-25oxaz-bala-beta34dcph 1922:2py-me24oxaz-ala-betapy 1923:tolhs-25methiaz-gly-betapym 1924:phhs-nme35pyr-gly-betahdcph 1925:tolhs-oxadiaz-gly-betafbph 1926:tolhs-25methiaz-bala-csdap 1927:bhs-24im-gly-psdap 1928:2py-me25oxaz-bala-beta34meoph 1929:ibhs-25oxaz-gly-betahdbph 1930:ibhs-oxadiaz-bala-betahcbph 1931:phhs-24thioph-bala-csdap 1932:tolhs-24thiaz-gly-betameph 1933:bhs-24thioph-gly-betacbph 1934:ibhs-24thiaz-gly-psdapee 1935:phhs-24thiaz-gly-betafluo 1936:gua-42pym-gly-betacthioph 1937:bhs-25thiaz-bala-betadhbfu 1938:bhs-oxadiaz-bala-betadhbfu 1939:phhs-25methiaz-gly-busu2be 1940:phhs-24thiaz-gly-psdap 1941:ibhs-24thioph-bala-betathiobe 1942;phhs-ithiadiaz-gly-betatbuph 1943:tolhs-25methiaz-bala-betahmofu 1944:sabhs-24thioph-gly-psdap 1945;ibhs-25oxaz-gly-betaoxope 1946:tolhs-25thiaz-gly-beta34dcph 1947:phhs-nme35pyr-gly-betabph 1948:phhs-25thiaz-gly-betatrif 1949:bhs-ithiadiaz-ala-betadito 1950:bim-25thiaz-ala-betameph 1951:2py-35fur-gly-betadcph 1952:ibhs-25methiaz-gly-betabdimo 1953:cima-24thioph-bala-psdap 1954:phhs-24thioph-gly-betafph 1955:ibhs-ithiadiaz-bala-betafphe 1956:bim-24im-leu-betapy 1957:bhs-25thioph-gly-betacph 1958:impy-24thiaz-bala-betainyl 1959:bim-25methiaz-bala-asppha WO 00166618 PCTlEP00l03469 1960:bhs-24thioph-bala-betadcphtb 1961:ibhs-oxadiaz-bala-psdaptb 1962:2py-me24thioph-gly-psdap 1963:2pmhs-24thiaz-bala-betamethioph 1964:ibhs-25methiaz-bala-betampy 1965:bhs-24thiophme-gly-betameph 1966:bhs-ithiadiaz-gly-betatrif 1967:dhim-26py-ala-betatbuph 1968:thpym-25thiaz-gly-betadcph 1969:2py-thiadiaz-ala-betapy 1970:~2py-25methiaz-bala-betaoxope 1971:tolhs-25methiaz-gly-ibsdap 1972:ibhs-ithiadiaz-gly-betaoxaz 1973:phhs-25thiaz-bala-asppha 1974:2py-42nmeim-gly-betampy 1975:2py-26py-ala-betapy 1976:phhs-24thiaz-gly-betadcphtb 1977:3pmhs-24thioph-bala-betapy 1978:2py-25thiaz-bala-aspbzla 1979:gua-42pym-gly-betahmo 1980:gua-26py-gly-betaamibe 1981:tolhs-25methiaz-gly-zdapee 1982:ibhs-25oxaz-gly-psdapch 1983:bhs-25thiaz-nmgly-betadmph 1984:bhs-nme35pyr-bala-betadmoph 1985:agua-25thiaz-gly-betadcph 1986:phhs-25methiaz-gly-betameph 1987:bhs-24thiaz-gly-beta35dbph 1988:ibhs-ithiadiaz-gly-betafphe 1989:bim-25oxaz-leu-betapy 1990:phhs-ithiadiaz-bala-betahmph 1991:2py-24thioph-bala-betaet 1992:2py-me24thiaz-gly-betaph 1993:2py-24im-ala-betadcph 1994:bhs-25thiaz-gly-betadmoph 1995:phhs-ithiadiaz-bala-betaet 1996:ibhs-25thiaz-bala-betaphethio W~ 00166618 PCTIEP00103469 1997:phhs-oxadiaz-bala-betahbcph 1998:ibhs-25methiaz-bala-betafphe 1999:ibhs-25thiaz-gly-suabu 2000:bim-24thiaz-ala-betameph 2001:phhs-me25thiaz-bala-betaph 2002:ibhs-25thiaz-gly-betapyr 2003:bhs-me25thioph-bala-betaph 2004:bhs-25oxaz-bala-aspaba 2005:2pmhs-25thiaz-bala-betathioph 2006:tolhs-oxadiaz-bala-psdap 2007:bhs-nme35pyr-gly-betaoxaz 2008:tolhs-25thiaz-gly-beta23meoph 2009:phhs-25methiaz-gly-betaamibe 2010:gua-25thioph-gly-betapy 2011:2py-nme35pyr-gly-psdap 2012:ibhs-ithiadiaz-gly-betahdbph 2013:2py-25oxaz-gly-betacbph 2014:bim-me24thioph-leu-zdap 2015:bhs-25thiaz-ala-beta13bendi 2016:phhs-24thioph-gly-betatrif 2017:2py-ith iad iaz-gly-betapy 2018:phhs-nme35pyr-gly-betapytb 2019:ibhs-ithiadiaz-gly-betaanaphth 2020:bhs-nme35pyr-ala-betaanaphth 2021:tolhs-nme35pyr-gly-betapych 2022:2py-me25thioph-bala-psdap 2023:ibhs-24thiaz-gly-betaet 2024.tolhs-24thioph-gly-beta3quin 2025:tolhs-24thiaz-bala-betaoxope 2026:ibhs-25methiaz-gly-beta34meoph 2027.ibhs-25oxaz-bala-betambiph 2028:phhs-25oxaz-gly-betafbph 2029:tolhs-24thiaz-gly-betathio3 2030:phhs-ithiadiaz-gly-betaipro 2031:phhs-25oxaz-gly-betacthioph 2032:bhs-25thiaz-bala-betaibph 2033:impy-24thioph-nmgly-psdap WO 00166618 PCTIEP00l03469 2034:bhs-24im-gly-zdap 2035:bhs-thiadiaz-leu-betapy 2036:gua-25thiophme-gly-betapy 2037:bhs-24thiaz-gly-betafluo 2038:toihs-oxadiaz-bala-betathioph 2039:bhs-24im-ala-betapy 2040:bhs-24thiaz-bala-betabph 2041:bim-25oxaz-bala-betathioph 2042:bhs-nme35pyr-gly-betaamibe 2043:phhs-25oxaz-gly-beta23meoph 2044:ibhs-ithiadiaz-gly-betabdimo 2045:phhs-25methiaz-gly-betaipro 2046:phhs-24thiaz-gly-beta34meoph 2047:phhs-25thiaz-gly-betafluo 2048:bhs-25methiaz-bala-betaanaphth 2049:tolhs-25thiaz-bala-psdapee 2050:tolhs-24thiaz-gly-betafphe 2051:bhs-24thioph-gly-betafluo 2052:phhs-nme35pyr-gly-betahni 2053:2py-me24thioph-bala-betapy 2054:ibhs-25methiaz-gly-betafbph 2055:2py-nme35pyr-bala-aspaba 2056:bhs-24thiaz-gly-betatbuph 2057:2py-42pym-gly-betapy 2058:tolhs-24thiaz-bala-betahmofu 2059:ibhs-25thiaz-gly-betatos 2060:ibhs-nme35pyr-bala-suabu 2061:ibhs-25methiaz-gly-betamethioph 2062:ibhs-25thiaz-bala-betadito 2063:hyd-24thiaz-bala-betameph 2064:tolhs-nme35pyr-gly-betacph 2065:bhs-25oxaz-ala-betafphe 2066:bhs-oxadiaz-gly-aspbzla 2067:tolhs-24thiaz-bala-ibsdap 2068:bim-ithiadiaz-leu-betadcph 2069:2py-24thioph-gly-betaol 2070:tolhs-24thiaz-gly-betamesu WO 00166618 PCTlEP00103469 2071:ibhs-24thiaz-gly-betahdcph 2072:bhs-25methiaz-nmgly-beta3quin 2073:ibhs-24thioph-gly-betaphethio 2074:bhs-24thioph-bala-betathiobe 2075:bhs-25thiaz-gly-asppha 2076:phhs-nme35pyr-bala-betaphethioa 2077:2py-25methiaz-leu-betadcph 2078:tolhs-ithiadiaz-bala-betafphe 2079:bhs-25oxaz-bala-betadmph 2080:bhs-nme35pyr-bala-betaftrif 2081:tolhs-25methiaz-gly-betapyee 2082:bim-oxadiaz-leu-psdap 2083:tolhs-ithiadiaz-gly-betahc 2084:gua-25thiaz-gly-betahc 2085:2py-53pyrazo-gly-zdap 2086:nmhs-42pym-gly-betainyl 2087:tolhs-24thiaz-gly-betainyl 2088:phhs-25oxaz-bala-psdapch 2089:bhs-24thiaz-gly-betathiome 2090:bhs-nme35pyr-gly-betabediox 2091:phhs-25thiaz-gly-betahph 2092:bhs-24thiaz-nmgly-betabpy 2093:ibhs-25methiaz-bala-betafu3 2094:phhs-24thioph-gly-betaoxope 2095:bhs-25methiaz-gly-busu2be 2096:dhim-24thiaz-ala-zdap 2097:bhs-ithiadiaz-bala-betainyl 2098:phhs-25methiaz-gly-betaomebendi 2099:bim-52thiaz-ala-betameph 2100:bim-35thioph-bala-zdap 2101:ibhs-25thiaz-bala-aspbzla 2102:ibhs-25thiaz-gly-busu2be 2103:tolhs-nme35pyr-gly-betaomebendi 2104;phhs-25methiaz-gly-betaet 2105:bhs-24thiaz-gly-betahdcph 2106:bim-42nmeim-gly-betah35dc 2107:bhs-me24thioph-gly-betapy WO OOI66618 . PCTIEP00103469 2108:phhs-25thiaz-gly-zdapee 2109:ibhs-nme35pyr-bala-betadbph 2110:tolhs-me25thiaz-giy-betaph 2111:bhs-me25thioph-bala-zdap 2112:impy-25oxaz-bala-betadmoph 2113:tolhs-25thiaz-bala-betal3bendi 2114:bhs-35fur-gly-psdap 2115:gua-25thioph-gly-betaph 2116:ibhs-25oxaz-bala-betaamibe 2117:2py-24oxaz-leu-betadcph 2118:ibhs-ithiadiaz-gly-betahmofu 2119:bim-25thioph-ala-betapy 2120:ibhs-ithiadiaz-gly-betadcphee 2121:tolhs-me25oxaz-gly-betadcph 2122:tolhs-25methiaz-bala-betaheph 2123:ibhs-ithiadiaz-gly-betapy 2124:bhs-35py-ala-betapy 2125:bhs-35thioph-bala-psdap 2126:tolhs-me24thioph-bala-zdap 2127:phhs-25methiaz-gly-betahdcph 2128:bhs-25thiaz-bala-psdapee 2129:bhs-me25thioph-gly-beta34meoph 2130:phhs-oxadiaz-gly-betahdcph 2131:tolhs-25oxaz-gly-betaanaphth 2132:tolhs-25thiaz-bala-csdap 2133:2py-ithiadiaz-leu-zdap 2134:ibhs-25oxaz-bala-betamethi 2135:bhs-25oxaz-bala-aspbzla 2136:phhs-nme35pyr-bala-betah35dc 2137:ibhs-24thioph-bala-betadcphch 2138:phhs-25methiaz-bala-betathiome 2139:2py-52thiaz-ala-betapy 2140:ibhs-24thioph-gly-betabdimo 2141:dimethpym-25thiaz-gly-betameph 2142:bhs-25methiaz-gly-betaftrif 2143:tolhs-24thiaz-gly-betacph 2144:bhs-oxadiaz-bala-betapytb WO OO1G6618 PCTlEP00103469 _84_ 2145:ibhs-oxadiaz-bala-betafbph 2146:ibhs-25thiaz-gly-betacbph 2147:phhs-24thioph-bala-betafluo 2148:phhs-me24thiaz-bala-beta34meoph 2149:tolhs-25thiaz-bala-betapyr 2150:phhs-25oxaz-bala-betadhbfu 2151:ibhs-25oxaz-bala-betadito 2152:bhs-24thioph-gly-betameph 2153:bhs-24thioph-bala-betacbph 2154:bim-25oxaz-gly-aspbzla 2155:impy-24thioph-gly-beta34meoph 2156:bhs-ithiadiaz-nmgly-betadmoph 2157:bim-35thioph-ala-betapy 2158:tolhs-25thiaz-bala-betadmph 2159:phhs-24thioph-bala-betaphethioa 2160:ibhs-25oxaz-bala-betafu2 2161:ibhs-nme35pyr-gly-betatrif 2162:2py-24thiaz-gly-beta3quin 2163:2pmhs-25thiaz-gly-psdap 2164:bhs-25oxaz-gly-betatos 2165:tolhs-25methiaz-gly-beta3quin 2166:tolhs-24thioph-bala-betabthioph 2167:impy-25methiaz-bala-betamesu 2168:phhs-25oxaz-bala-psdapee 2169:tolhs-25thiaz-gly-betah35dc 2170:tolhs-24thioph-bala-betafu3 2171:bhs-25methiaz-gly-betabdimo 2172:bhs-25fur-gly-betadcph 2173:phhs-ithiadiaz-bala-psdapch 2174:tolhs-25oxaz-gly-betadito 2175:tolhs-oxadiaz-gly-betamesu 2176:bhs-25oxaz-bala-betabenfu 2177:ibhs-25methiaz-gly-betadcph 2178:bhs-24thioph-gly-betadito 2179:ibhs-24thiaz-bala-betaoxope .

2180:tolhs-25methiaz-bala-betampy 2181:ibhs-ithiadiaz-bala-aspaba 2182: 2py-me25oxaz-ala-betadcph 2183: ibhs-24thioph-gly-betapytb 2184: ibhs-ithiadiaz-bala-betainyl 2185: phhs-me25thiaz-gly-psdap 2186: phhs-oxadiaz-g1y-betahb 2187: bhs-nme35pyr-ala-beta34dcph 2188: phhs-me24thiaz-ala-zdap 2189: bhs-42nmeim-leu-betapy 2190: tolhs-24thiaz-gly-betaftrif 2191:ibhs-oxadiaz-gly-betahmph 2192: tolhs-ithiadiaz-bala-betahb 2193: bhs-35thioph-leu-betadcph 2194: bhs-25thiaz-bala-betadcph 2195: phhs-nme35pyr-gly-betapyr 2196:ibhs-ithiadiaz-gly-zdap 2197: phhs-25oxaz-bala-betahdcph 2198: bhs-oxadiaz-gly-betaibph 2199: 2py-me24thioph-leu-betaph 2200: tolhs-24thioph-gly-beta34dcph 2201:bhs-24thiaz-nmgly-betacph 2202: bhs-25oxaz-bala-betapyr 2203: bhs-25fur-leu-zdap 2204: impy-24oxaz-gly-betameph 2205: bhs-nme35pyr-gly-betahb 2206:tolhs-me24thiaz-bala-psdap 2207: ibhs-24thioph-gly-beta35dbph 2208: ibhs-24thioph-bala-betathio3 2209: bhs-24thiaz-bala-asppha 2210: bhs-24thioph-ala-betaanaphth 2211:ibhs-24thioph-bala-betahph 2212: tolhs-nme35pyr-bala-asppha 2213: bim-thiadiaz-leu-zdap 2214: 2py-35fu r-bala-betapy 2215: phhs-24thioph-bala-betathioph 2216:phhs-ithiadiaz-bala-betadhbfu 2217: bhs-25thiaz-nmgly-betameph 2218: tolhs-ithiadiaz-gly-betahb 2219:2py-ithiadiaz-gly-aspibua 2220:ibhs-25methiaz-bala-betamethioph 2221:bhs-oxadiaz-gly-betaet 2222:ibhs-nme35pyr-gly-betatos 2223:bhs-me25oxaz-gly-psdap 2224:bhs-25oxaz-bafa-zdapee 2225:bhs-26py-gly-beta13bendi 2226:bhs-25fur-ala-betadcph 2227:ibhs-24thioph-gly-zdapch 2228:tolhs-25thiaz-bala-betadcphtb 2229:phhs-24thioph-bala-betadbph 2230:2py-25oxaz-bala-aspbzla 2231:2py-me25thioph-ala-beta34meoph 2232:ibhs-25thiaz-bala-beta34meoph 2233:ibhs-24thioph-bala-zdap 2234:phhs-24thiaz-bala-betathio3 2235:bhs-24thioph-bala-betatrif 2236:bhs-nme35pyr-bala-betadito 2237:phhs-nme35pyr-gly-betacbph 2238:bhs-24thioph-ala-betaoxaz 2239:impy-25thiaz-bala-betaphethioa 2240:2py-25oxaz-bala-betafu3 2241:2py-oxadiaz-ala-betapy 2242:ibhs-25methiaz-bala-betaet 2243:ibhs-ithiadiaz-gly-betatbuph 2244:phhs-24thioph-bala-betaol 2245:phhs-25thiaz-bala-beta23meoph 2246:phhs-25oxaz-bala-betabthioph 2247:bim-24im-bala-psdap 2248:bim-nme35pyr-gly-aspaba 2249:ibhs-25oxaz-bala-betaimid 2250:impy-24thiaz-gly-betaipr 2251:tolhs-25thiaz-bala-betapbiph 2252:phhs-25oxaz-bala-betadcph 2253:ibhs-ithiadiazgly-beta-4bph 2254:bhs-oxadiaz-gly-betah35dc 2255:phhs-oxadiaz-gly-betaipro WO 00!66618 PCTIEP00103469 _87_ 2256:bhs-25methiaz-nmgly-betathio3 2257:bim-35thioph-leu-zdap 2258:phhs-25oxaz-bala-betaipr 2259:ibhs-25methiaz-gly-zdapch 2260:bim-me25thiaz-bala-zdap 2261:phhs-nme35pyr-bala-betaamibe 2262:bhs-25thiaz-bala-aspaba 2263:bhs-24thiaz-gly-betathioph 2264:bhs-25oxaz-gly-betaphethio 2265:bhs-ithiadiaz-bala-betabediox 2266:phhs-nme35pyr-gly-betabnaphth 2267:bhs-nme35pyr-gly-betadtrif 2268:tolhs-25thiaz-bala-betainyl 2269:bhs-24thioph-gly-betabnaphth 2270:phhs-ithiadiaz-bala-betacbph 2271:bhs-25methiaz-bala-betatbuph 2272:bhs-25methiaz-ala-betathio3 2273:bim-25methiaz-gly-zdap 2274:tolhs-oxadiaz-gly-betafu2 2275:ibhs-24thiaz-bala-beta35dbph 2276:bhs-nme35pyr-gly-betadito 2277:bhs-oxadiaz-ala-ibsdap 2278:ibhs-25methiaz-gly-beta13bendi 2279:phhs-24thioph-bala-psdap 2280:ibhs-ithiadiaz-bala-betatos 2281:tolhs-25thiaz-gly-psdapch 2282:bhs-25methiaz-gly-betadhbfu 2283:phhs-24thiaz-gly-betaipro 2284:ibhs-oxadiaz-gly-zdap 2285:tolhs-nme35pyr-bala-betafphe 2286:bhs-25thiaz-ala-betaoxaz 2287:ibhs-24thioph-bala-betaet 2288:ibhs-24thiaz-bala-betafu3 2289:bhs-25oxaz-ala-ibsdap 2290:bhs-25methiaz-nmgly-betadito 2291:bim-24thioph-gly-betapbiph 2292:ibhs-25thiaz-bala-betadtrif _88_ 2293:tolhs-25methiaz-bala-betah35dc 2294:phhs-25methiaz-gly-betabdimo 2295:2py-25oxaz-bala-aspibua 2296:ibhs-25thiaz-bala-betahmofu 2297:phhs-oxadiaz-gly-betathiome 2298:tolhs-oxadiaz-gly-betaomebendi 2299:tolhs-25thiaz-gly-betabmph 2300:ibhs-oxadiaz-bala-betahdcph 2301:2py-me24thioph-leu-beta34meoph 2302:phhs-nme35pyr-gly-betabediox 2303:ibhs-nme35pyr-bala-betaibph 2304:2py-me25thioph-bala-beta34meoph 2305:bhs-24thiaz-bala-betatos 2306:bhs-25thiaz-gly-betaol 2307:phhs-25oxaz-gly-betahb 2308:ibhs-oxadiaz-bala-betaphethioa 2309:tolhs-25thiaz-bala-betahmofu 2310:bhs-nme35pyr-ala-betahph 2311:ibhs-25oxaz-bala-betaibph 2312:tolhs-25oxaz-bala-betadmph 2313:2py-me25oxaz-bala-zdap 2314:bhs-24thiaz-gly-betacph 2315:bim-oxadiaz-ala-zdap 2316:tolhs-25oxaz-bala-betamethi 2317:2py-25thioph-ala-betadcph 2318:bhs-24thiaz-nmgly-ibsdap 2319:bim-42nmeim-gly-busu2be 2320:phhs-me24thioph-ala-betadcph 2321:bhs-24thiaz-nmgly-betadhbfu 2322:2py-me25thiaz-bala-betapy 2323:bim-25thioph-gly-zdap 2324:tolhs-25oxaz-gly-betahmofu 2325:bhs-25methiaz-gly-betahmofu 2326:phhs-ithiadiaz-bala-suabu 2327:ibhs-25oxaz-gly-betamethi 2328:gua-26py-gly-betapy 2329:tolhs-25oxaz-gly-betapy _ 89 2330:bhs-me25oxaz-ala-betaph 2331:tolhs-nme35pyr-gly-betambiph 2332:bhs-24thioph-gly-betathiome 2333:phhs-25thiaz-gly-betaet 2334:tolhs-ithiadiaz-bala-betapyr 2335:phhs-24thioph-bala-zdapch 2336:tolhs-25methiaz-gly-zdap 2337:ibhs-24thiaz-gly-betacbph 2338:bhs-oxadiaz-bala-betahph 2339:tolhs-24thiaz-bala-betafu2 2340:ibhs-24thiaz-gly-psdap 2341:ibhs-ithiadiaz-bala-betabenfu 2342:bim-25oxaz-bala-psdap 2343:phhs-me25oxaz-leu-betapy 2344:ibhs-nme35pyr-bala-betabph 2345:bim-me25thioph-leu-betadcph 2346:bhs-ithiadiaz-bala-betabenfu 2347:phhs-25methiaz-bala-betabithioph 2348:bhs-nme35pyr-bala-psdapee 2349:ibhs-24thioph-bala-betabdimo 2350:ibhs-24thioph-gly-betaoxope 2351:bim-42pym-ala-zdap 2352:gua-26py-gly-suabu 2353:ibhs-25thiaz-bala-betaipro 2354:phhs-ithiadiaz-gly-betapytb 2355:2pmhs-25thiaz-gly-betameph 2356.bim-me24thioph-bala-psdap 2357:phhs-25thiaz-bala-betaphethio 2358:tolhs-oxadiaz-bala-betahbcph 2359:bhs-26py-gly-psdap 2360:bhs-24thiaz-gly-betaanaphth 2361:dhim-2thioph-gly-betameph 2362:2py-me24thioph-leu-betadcph 2363:tolhs-24thiaz-bala-betabmph 2364:bhs-25oxaz-bala-beta35dbph 2365:tolhs-25methiaz-gly-betadhbfu 2366:bhs-24thioph-bala-betafluo 2367:tolhs-24thiaz-bala-betaol 2368:bim-24thioph-gly-betadbph 2369:phhs-24thioph-bala-betabph 2370:phhs-nme35pyr-bala-betacbph 2371:tolhs-ithiadiaz-bala-betadhbfu 2372:2py-24oxaz-gly-betainyl 2373:ibhs-24thioph-gly-zdaptb 2374:2py-25fur-leu-betadcph 2375:bhs-24thiaz-gly-betaimid 2376:ibhs-25methiaz-bala-beta13bendi 2377:bhs-24thiaz-bala-betapyr 2378:ibhs-24thiaz-bala-suabu 2379:tolhs-oxadia~-gly-betambiph 2380:bhs-oxadiaz-nmgly-betathioph 2381:phhs-25methiaz-gly-betabediox 2382:ibhs-25thiaz-gly-betameph 2383:phhs-24thioph-bala-betaipro 2384:bhs-24chin-ala-betameph 2385:tolhs-25oxaz-gly-betainyl 2386:2py-25oxaz-bala-betapy 2387:tolhs-25methiaz-gly-betacph 2388:ibhs-25oxaz-bala-beta 13bendi 2389:tolhs-25oxaz-gly-beta3quin 2390:ibhs-25oxaz-bala-zdap 2391:tolhs-24thioph-bala-beta13bendi 2392:phhs-me24oxaz-bala-psdap 2393:bim-24thioph-bala-betatos 2394:tolhs-me25oxaz-ala-zdap 2395:bhs-me24oxaz-bala-zdap 2396:bhs-25thiaz-bala-betadbph 2397:phhs-ithiadiaz-gly-betainyl 2398:ibhs-ithiadiaz-gly-betapytb 2399:ibhs-24thiaz-gly-betah35dc 2400:tolhs-24thiaz-gly-betatbuph 2401:phhs-24thiaz-bala-betampy 2402:bhs-53pyrazo-bala-betapy 2403:2py-25oxaz-bala-betadcph PCTlEP00103469 _91_ 2404: phhs-me24thioph-ieu-betapy 2405: tolhs-ithiadiaz-bala-betaanaphth 2406: ibhs-oxadiaz-bala-betaph 2407: phhs-25methiaz-gly-betafu2 2408: phhs-24thioph-gly-betadbph 2409: phhs-24thioph-bala-psdapee 2410: ibhs-24thiaz-bala-betacph 2411: bhs-me25thiaz-giy-betadcph 2412: phhs-oxadiaz-bala-betabpy 2413: ibhs-24thioph-gly-beta34dcph 2414: ibhs-25thiaz-gly-betapbiph 2415: tolhs-24thiaz-bala-beta34meoph 2416: tolhs-ithiadiaz-bala-betapbiph 2417: phhs-nme35pyr-bala-betadcph 2418: 2pmhs-25methiaz-giy-betathiome 2419: bhs-me25thiaz-bala-psdap 2420: phhs-ithiadiaz-gly-betabenfu 2421: 2py-nme35pyr-leu-betadcph 2422: phhs-24thioph-bala-betadmph 2423: bhs-24thioph-bala-betahcbph 2424: 2py-25methiaz-bala-asppha 2425: 2py-2gpy_giy-betampy 2426: ibhs-nme35pyr-gly-zdapch 2427: tolhs-me24thiaz-ala-betapy 2428: toihs-nme35pyr-gly-betapbiph 2429: phhs-ithiadiaz-gly-betapyee 2430: bhs-25oxaz-gly-beta34meoph 2431: 2py-35thioph-leu-betadcph 2432: ibhs-nme35pyr-gly-betabph 2433: bhs-ithiadiaz-gly-betaphethio 2434: tolhs-25thiaz-gly-zdapch 2435: 2py-24thioph-ala-zdap 2436: toihs-ithiadiaz-gly-betahph 2437: phhs-25methiaz-bala-betaphethioa 2438: ibhs-25oxaz-gly-betah35dc 2439: gua-25thioph-gly-betaphethio 2440: bim-35fur-gly-psdap 2441: ibhs-ithiadiaz-bala-betaftrif 2442: tolhs-24thiaz-gly-beta34meoph 2443: bhs-25methiaz-bala-betacthioph 2444: bhs-nme35pyr ala-betaoxaz 2445: 2py-me24thioph-gly-zdap 2446: 2py-25oxaz-gly-betambiph 2447: bhs-42nmeim-gly-psdap 2448: bhs-oxadiaz-gly-psdapee 2449: phhs-ithiadiaz-gly-betafph 2450: thazep-42pym-gay-beta13bendi 2451: phhs-25methiaz-bala-betabmph 2452: bhs-25methiaz-bala-betapbiph 2453: phhs-nme35pyr-gly-suabu 2454: ibhs-ithiadiaz-bala-betamethioph 2455: 2pmhs-24thioph-gly-betafph 2456: tolhs-24thiaz-gly-betacbph 2457: phhs-25thiaz-bala-betathio3 2458: ibhs-oxadiaz-bala-betamethioph 2459: ibhs-25thiaz-gly-aspibua 2460: bhs-42nmeim-bala-betadcph 2461: phhs-25oxaz-bala-betaomebendi 2462: phhs-nme35pyr-gly-asppha 2463: ibhs-24thiaz-baia-betainyl 2464: bim-25oxaz-gly-aspibua 2465: bhs-ithiadiaz-ala-betafphe 2466: bhs-25oxaz-bala-betafphe 2467: ibhs-ithiadiaz-gly-betaibph 2468: gua-26py-gly-betabnaphth 2469: ibhs-25oxaz-gly-betathioph 2470: phhs-25methiaz-gly-betathiobe 2471: ibhs-24thiaz-gly-betadbph 2472: tolhs-ithiadiaz-gly-betabthioph 2473: bhs-oxadiaz-gly-busu2be 2474: phhs-24thioph-gly-betaphethioa 2475: bhs-24thiaz-ala-betameph 2476: tolhs-25thiaz-bala-betaol 2477: bhs-ithiadiaz-bala-betahmofu 2478: phhs-ithiadiaz-bala-betaph 2479: bhs-35fur-gly-betapy 2480: ibhs-24thioph-bala-betapych 2481: phhs-25oxaz-gly-beta13bendi 2482: bhs-25thiaz-ala-betadito 2483: bhs-ithiadiaz-bala-psdap 2484: bim-24thioph-bala-betaipro 2485: phhs-24thioph-bala-beta34dcph 2486: tolhs-me24thioph-leu-betapy 2487:phhs-25methiaz-gly-betahmph 2488: tolhs-oxadiaz-gly-betatbuph 2489: bhs-me24thioph-bala-zdap 2490: phhs-24thioph-gly-betahmo 2491: bhs-nme35pyr-gly-betabmph 2492:bim-24thioph-gly-zdap 2493: ibhs-25thiaz-bala-betahc 2494: ibhs-ithiadiaz-bala-zdaptb 2495: bhs-24thiaz-gly-betadcphee 2496: ibhs-24thioph-bala-betacbph 2497:ibhs-ithiadiaz-bala-betaph 2498: ibhs-25methiaz-gly-betahdcph 2499: phhs-24thiaz-bala-betafbph 2500: phhs-25oxaz-gly-betadhbfu 2501: bhs-42oxaz-leu-zdap 2502:phhs-ithiadiaz-gly-betaomebendi 2503: phhs-24thiaz-bala-beta4bph 2504: bhs-24thioph-bala-betaipro 2505: phhs-oxadiaz-bala-betahc 2506: tolhs-25oxaz-bala-betadito 2507:bhs-nme35pyr-gly-betapbiph 2508: bhs-25methiaz-gly-betameph 2509: ibhs-25oxaz-bala-beta4bph 2510: ibhs-ithiadiaz-bala-betadtrif 2511: bhs-ithiadiaz-gly-betabph 2512:bhs-25oxaz-bala-beta13bendi 2513: tolhs-25oxaz-bala-betafluo 2514: tolhs-25thiaz-bala-aspibua 2515: ibhs-24thiaz-gly-betapytb 2516: tolhs-me25oxaz-leu-psdap 2517: phhs-25methiaz-bala-betahph 2518: bhs-24thioph-ala-betadhbfu 2519: bim-24thiaz-phg-zdap 2520: bhs-me25thiaz-bala-betapy 2521: 2py-35fur-bala-psdap 2522: phhs-me25thioph-ala-betadcph 2523: bhs-me25thiaz-gly-betaph 102524: phhs-25thiaz-gly-asppha 2525: phhs-25methiaz-gly-betadcphtb 2526: ibhs-nme35pyr-bala-betapbiph 2527: phhs-ithiadiaz-gly-betadtrif 2528: bhs-24thiaz-gly-betabdimo 152529: bhs-25methiaz-ala-betabnaphth 2530: 2py-me25thiaz-leu-zdap 2531: ibhs-24thiaz-gly-betaipr 2532: dhim-25thioph-gly-betahcbph 2533: tolhs-me24thiaz-leu-beta34imeoph 202534: bhs-25thiaz-bala-betaipro 2535: bim-me24thiaz-ala-psdap 2536: gua-25thioph-gly-betapbiph 2537: 2pmhs-24thioph-gly-betaph 2538: bhs-24thioph-bala-betaibph 252539. tolhs-24thioph-bala-betabnaphth 2540: bhs-nme35pyr-bala-betampy 2541: bim-ithiadiaz-bala-aspbzla 2542: ur-25thioph-gly-zdap 2543: bhs-24thioph-gly-betatos 302544: bhs-nme35pyr-gly-aspaba 2545: tolhs-ithiadiaz-gly-zdapch 2546: ibhs-24thioph-gly-betapyr 2547: bhs-ithiadiaz-bala-betaibph 2548: bhs-25methiaz-bala-betathiobe 352549: ibhs-25thiaz-bala-beta13bendi 2550: bhs-24thioph-ala-betainyl 2551: 2pmhs-25oxaz-gly-betadito 2552:tolhs-oxadiaz-bala-ibsdap 2553:bim-me24oxaz-leu-betadcph 2554:phhs-25thiaz-bala-betainyl 2555:phhs-me24oxaz-bala-betaph 2556:bhs-23thioph-gly-betapy 2557:tolhs-25methiaz-bala-betafbph 2558:bhs-oxadiaz-bala-betabenfu 2559:phhs-24thiaz-gly-betadcph 2560:phhs-25oxaz-gly-betaomebendi 2561:tolhs-nme35pyr-gly-betadcph 2562:ibhs-24thioph-bala-zdapch 2563:tolhs-nme35pyr-gly-betah35dc 2564:ibhs-25thiaz-gly-betabthioph 2565:tolhs-24thioph-gly-betabediox 2566:bhs-25thiaz-gly-betathiobe 2567:phhs-oxadiaz-bala-beta3quin 2568:ibhs-25thiaz-gly-betaph 2569:phhs-25thiaz-gly-betampy 2570:ibhs-nme35pyr-gly-betabdimo 2571:2py-25methiaz-hphe-psdap 2572:phhs-ithiadiaz-gly-betahni 2573:bhs-nme35pyr-ala-betafphe 2574:2py-52thiaz-ala-betameph 2575:gua-24thiaz-gly-betafph 2576:ibhs-24thioph-bala-beta4bph 2577:bhs-24thiaz-bala-betaheph 2578:ibhs-25methiaz-giy-betaph 2579:phhs-nme35pyr-gly-betahcbph 2580:phhs-ithiadiaz-bala-betah35dc 2581:bhs-oxadiaz-bala-beta23meoph 2582:bim-25thiaz-gly-betaibph 2583:tolhs-25methiaz-bala-beta34dcph 2584:tolhs-24thioph-gly-zdapee 2585:tolhs-oxadiaz-gly-betahmo 2586:4pmhs-24oxaz-gly-betameph 2587:ibhs-ithiadiaz-bala-betafbph 2588:bhs-oxadiaz-bala-betaftrif WO 00/66618 PCTlEP00103469 2589: gua-24oxaz-gly-betafu2 2590: tolhs-me24thiaz-gly-betadcph 2591: bhs-25thiaz-bala-betathiome 2592: impy-25oxaz-gly-betameph 2593:ibhs-25thiaz-bala-betafbph 2594: tolhs-24thiaz-bala-betaipro 2595: tolhs-25oxaz-bala-betapytb 2596: bim-me24thioph-leu-betapy 2597: tolhs-24thioph-gly-betaphethio 2598:Zpy-25thioph-gly-psdap 2599: bhs-25thiaz-gly-betahmo 2600: tolhs-oxadiaz-bala-aspaba 2601: bhs-oxadiaz-leu-zdap 2602: hs-24thiaz-bafa-betapy 2603:bhs-25thiaz-gly-betaoxope 2604: bhs-24thioph-bala-betathioph 2605: tolhs-ithiadiaz-bala-betabpy 2606: phhs-ithiadiaz-gly-betamethi 2607: phhs-24thiaz-gly-betatrif 2608:ibhs-nme35pyr-gly-betahmph 2609: phhs-25oxaz-bala-betacbph 2610: tolhs-25thiaz-gly-asppha 2611: bhs-25thiaz-bala-betahc 2612: tolhs-25thiaz-gly-betaph 2613:bhs-ithiadiaz-gly-zdapee 2614: bhs-25oxaz-bala-betamesu 2615: bhs-nme35pyr-gly-betahc 2616: tolhs-me25thiaz-gly-betapy 2617: bhs-oxadiaz-bala-betafph 2618:bim-nme35pyr-leu-betadcph 2619: tolhs-nme35pyr-bala-betamesu 2620: dhim-25thiaz-gly-betameph 2621: tolhs-me25thioph-ala-betapy 2622: ibhs-oxadiaz-bala-betaamibe 2623:impy-24thiaz-gly-betabthioph 2624: ibhs-25oxaz-bala-betaph 2625: bhs-25methiaz-gly-betapych WO 0016661$ PCTIEP00103469 _97_ 2626:bhs-25methiaz-gly-betambiph 2627:tolhs-25oxaz-gly-betadtrif 2628:bhs-25methiaz-nmgly-betadmph 2629:bhs-25thiaz-ala-betabpy 2630:ibhs-25oxaz-gly-betacthioph 2631:2py-24thioph-gly-betacthioph 2632:bhs-24thioph-gly-betadcphee 2633:ibhs-25oxaz-gly-betadbph 2634:phhs-24thiaz-gly-betapym 2635:tolhs-nme35pyr-bala-betathiome 2636:bhs-ithiadiaz-ala-betadmph 2637:bhs-25thiaz-bala-betahmo 2638:bhs-25methiaz-nmgly-betahph 2639:tolhs-nme35pyr-gly-betameph 2640:ibhs-25methiaz-gly-betaomebendi 2641:bim-25oxaz-bala-beta4bph 2642:2py-24thiaz-gly-betainyl 2643:bhs-ithiadiaz-bala-betaipr 2644:bhs-25thiaz-bala-betahdbph 2645:ibhs-25oxaz-gly-betahcbph 2646:tolhs-24thiaz-bala-betaibph 2647:2py-25fur-gly-psdap 2648:phhs-25thiaz-bala-betaph 2649:bhs-24thiaz-gly-betapy 2650:ibhs-nme35pyr-bala-betabthioph 2651:tolhs-ithiadiaz-gly-betainyl 2652:dhpyrr-42nmeim-gly-zdap 2653:bhs-nme35pyr-gly-csdap 2654:gua-25thiaz-gly-betatos 2655:bhs-24thioph-gly-betatbuph 2656:ibhs-25oxaz-bala-betatbuph 2657:bhs-25thiaz-bala-betabenfu 2658:ibhs-nme35pyr-gly-betapy 2659:2py-26py-gly-ibsdap 2660:2py-24thiaz-bala-aspibua 2661:bhs-oxadiaz-gly-betabediox 2662:phhs-nme35pyr-bala-betafu2 _98_ 2663:bhs-thiadiaz-ala-betadcph 2664;bhs-oxadiaz-bala-betaheph 2665;bhs-25thiaz-gly-beta34meoph 2666:bhs-25methiaz-bala-betadmph 2667:bhs-25thiaz-bala-betaftrif 2668:ibhs-24oxaz-gly-zdap 2669:tolhs-ithiadiaz-bala-betah35dc 2670:2py-24thiaz-bala-betafluo 2671:agua-24thiaz-gly-betainyl 2672:bim-25methiaz-bala-aspaba 2673:bhs-25thiaz-gly-betahmph 2674:phhs-25thiaz-bala-betaet 2675:bhs-25thiaz-bala-psdapch 2676:phhs-oxadiaz-gly-betadcph 2677:2py-42nmeim-nmala-betapy 2678:ibhs-26py-gly-betainyl 2679:phhs-25methiaz-gly-ibsdap 2680:bim-42pym-ala-psdap 2681:phhs-24thiaz-bala-betahph 2682:tolhs-24thioph-gly-betabdimo 2683:ibhs-25oxaz-bala-betatrif 2684:bhs-nme35pyr-ala-zdap 2685:bhs-25fur-bala-betapy 2686:phhs-24thioph-gly-betabnaphth 2687:tolhs-nme35pyr-bala-betathioph 2688:phhs-25methiaz-bala-betaamibe 2689:tolhs-24thiaz-bala-betafbph 2690:ibhs-oxadiaz-gly-psdaptb 2691:tolhs-nme35pyr-gly-suabu 2692:tolhs-25methiaz-gly-betabnaphth 2693:bhs-25oxaz-mngly-betabnaphth 2694:ibhs-25thiaz-bala-betapytb 2695:tolhs-nme35pyr-bala-psdapee 2696:2py-24thioph-gly-betadcph 2697:sabhs-25thiaz-ala-betameph 2698:bhs-25methiaz-gly-betathio3 2699:ibhs-25methiaz-gly-psdaptb _99_ 2700:bhs-nme35pyr-gly-betapym 2701:ibhs-25thiaz-gly-ibsdap 2702:impy-25methiaz-bala-betaftrif 2703:tolhs-25methiaz-gly-betafluo 2704:ibhs-25oxaz-bala-betaoxope 2705:gua-26py-gly-betafbph 2706:bhs-nme35pyr-bala-betahb 2707:ibhs-nme35pyr-bala-betapyee 2708:bhs-24oxaz-bala-psdap 2709:bhs-25oxaz-bala-betahdbph 2710:phhs-25oxaz-bala-zdap 2711:phhs-25methiaz-gly-betah35dc 2712:ibhs-25thiaz-bala-betacph 2713:tolhs-25thiaz-gly-betaamibe 2714:bhs-ithiadiaz-bala-betahmo 2715:tolhs-24thiaz-gly-suabu 2716:phhs-nme35pyr-gly-betaol 2717:phhs-24thiaz-bala-betapbiph 2718:bhs-oxadiaz-nmgly-betadito 2719:tolhs-ithiadiaz-gly-betaanaphth 2720:tolhs-25thiaz-gly-busu2be 2721:bim-24im-ala-betadcph 2722:ibhs-25thiaz-gly-betahmofu 2723:tolhs-oxadiaz-bala-betaomebendi 2724:bhs-ithiadiaz-gly-betadtrif 2725:ibhs-25methiaz-gly-betathioph 2726:phhs-25methiaz-bala-betahdbph 2727:bhs-nme35pyr-bala-betaol 2728:gua-26py-gly-betahc 2729:ibhs-25oxaz-bala-beta34meoph 2730:bim-25methiaz-bala-betahcbph 2731:phhs-nme35pyr-bala-betafph 2732:tolhs-25oxaz-bala-betaet 2733:2py-nme35pyr-gly-betadcph 2734:tolhs-oxadiaz-gly-betaol 2735:bhs-24im-ala-zdap 2736:2py-35thioph-gly-betadcph 2737:tolhs-25methiaz-gly-psdapee 2738:impy-25methiaz-bala-psdap 2739:ibhs-25methiaz-bala-betabediox 2740:tolhs-nme35pyr-bala-betaphethioa 2741:tolhs-ithiadiaz-gly-betahbcph 2742:thazep-24thioph-bala-zdap 2743:dhim-25py-gly-betameph 2744:2py-25fur-gly-betapy 2745:impy-42nmeim-gly-betabmph 2746:tolhs-24thioph-gly-betacbph 2747:phhs-oxadiaz-bala-betaftrif 2748:tolhs-25thiaz-bala-betacph 2749:phhs-24thiaz-bala-betadito 2750:bhs-25fur-ala-betapy 2751:ibhs=25oxaz-gly-betahb 2752:tolhs-24thiaz-bala-zdapee 2753:bhs-25oxaz-gly-betahmo 2754:gua-24thiaz-gly-betamethioph 2755:nmhs-24thiaz-gly-betapy 2756:phhs-25thiaz-gly-betafph 2757:tolhs-25oxaz-gly-betadmoph 2758:phhs-oxadiaz-bala-betaet 2759:bhs-24thiaz-gly-psdapee 2760:ibhs-24thiaz-bala-betabediox 2761:gua-24thiaz-gly-betafu3 2762:tolhs-nme35pyr-bala-betaphethio 2763:ibhs-24thioph-gly-psdap 2764:tolhs-me24oxaz-leu-beta34meoph 2765:2py-24thioph-bala-aspaba 2766:bim-me24oxaz-leu-psdap 2767:bhs-nme35pyr-bala-betamesu 2768:bhs-thiadiaz-gly-zdap 2769:2py-oxadiaz-ala-zdap 2770:bim-25methiaz-gly-betapbiph 2771:ibhs-24thioph-gly-betadcphee 2772:tolhs-nme35pyr-bala-betahdcph 2773:bhs-me24thioph-gly-betadcph 2774:phhs-25thiaz-bala-zdapch 2775:bhs-25thiaz-gly-betapych 2776:bhs-ithiadiaz-bala-betahdbph 2777:impy-24thiaz-nmgly-psdap 2778:bim-25oxaz-bala-beta13bendi 2779:bim-oxadiaz-bala-betapy 2780:tolhs-24thiaz-bala-betahdcph 2781:2py-nme35pyr-ala-psdap 2782:ibhs-25thiaz-gly-betadtrif 2783:phhs-25thiaz-gly-betahbcph 2784:ibhs-oxadiaz-bala-zdapch 2785:dhim-26py-hphe-zdap 2786:phhs-nme35pyr-gly-betahbcph 2787:bhs-25thiaz-bala-betafluo 2788:ibhs-oxadiaz-gly-beta3quin 2789:2py-35fur-bala-betadcph 2790:2py-me25oxaz-gly-betadcph 2791:bhs-24thiaz-gly-betaipr 2792:bhs-25methiaz-bala-betabediox 2793:ibhs-ithiadiaz-gly-betaph 2794:phhs-25thiaz-bala-aspibua 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2827:bhs-oxadiaz-gly-beta13bendi 2828:ibhs-oxadiaz-gly-zdapee 2829:2py-me24thioph-bala-psdap 2830:bhs-25thiaz-bala-betacbph 2831:2py-me25oxaz-leu-betadcph 2832:tolhs-25thiaz-bala-betahcbph 2833:ibhs-25oxaz-bala-betabdimo 2834:2py-25thioph-ala-betainyl 2835:bhs-oxadiaz-bala-betathioph 2836:bhs-25methiaz-gly-betaipro 2837:bhs-24thioph-ala-betapy 2838:ibhs-25thiaz-gly-betafluo 2839:2py-24oxaz-gly-zdap 2840:phhs-oxadiaz-bala-betadcphee 2841:2py-24thiaz-ala-betadcph 2842:ibhs-24thiaz-gly-betaheph 2843:bhs-me25oxaz-ala-betapy 2844:ibhs-nme35pyr-bala-betaomebendi 2845:bhs-thiadiaz-gly-betapy 2846:bhs-25thiaz-gly-betadhbfu 2847:dhim-24oxaz-gly-betapy WO 00!66618 PCTIEP00103469 2848:gua-24thiaz-gly-betafluo 2849:bhs-thiadiaz-bala-zdap 2850:ibhs-25oxaz-gly-betahni 2851:tolhs-25thiaz-bala-betahc 2852:bhs-nme35pyr-ala-ibsdap 2853:bhs-oxadiaz-gly-betabdimo 2854:phhs-me24thiaz-leu-betaph 2855;tolhs-25thiaz-bala-betathioph 2856:bhs-25oxaz-bala-betatrif 2857:ibhs-24thiaz-gly-betamesu 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2890:2py-me24thiaz-bala-zdap 2891:bhs-me25thioph-gly-betaph 2892:phhs-nme35pyr-bala-betaet 2893:bim-24thiaz-gly-betaanaphth 2894:bhs-24thiaz-ala-betathioph 2895:bhs-53pyrazo-leu-zdap 2896:2py-42nmeim-bala-betahmph 2897:2py-me25oxaz-gly-betapy 2898:tolhs-24thioph-gly-betamethi 2899:bhs-24thioph-bala-betadbph 2900:ibhs-25thiaz-gly-beta35dbph 2901:phhs-24thioph-bala-aspbzla 2902:tolhs-24thioph-bala-beta35dbph 2903:bhs-nme35pyr-baia-betaipr 2904:bim-me24thiaz-bala-beta34meoph 2905:ibhs-24thioph-gly-betamesu 2906:2py-me25thioph-gly-betaph 2907:dhim-25thioph-ala-psdap 2908:impy-24thiaz-ala-betapy 2909:tolhs-nme35pyr-gly-betahbcph 2910:tolhs-oxadiaz-gly-betacthioph 2911:bhs-nme35pyr-gly-betahph 2912:tolhs-25oxaz-gly-betaipro 2913:phhs-25vxaz-bala-betahni 2914:ibhs-25methiaz-bala-csdap 2915:2py-25thiaz-ala-psdap 2916:tolhs-me24oxaz-gly-psdap 2917:ibhs-ithiadiaz-gly-betaftrif 2918:phhs-nme35pyr-gly-betadtrif 2919:2pmhs-25methiaz-bala-beta13bendi 2920:bhs-oxadiaz-nmgly-beta34dcph 2921:bim-25thiaz-bala-betaipro 2922:phhs-oxadiaz-gly-betabthioph 2923:bhs-24thioph-gly-betahmo 2924:phhs-24thioph-bala-betahmofu 2925:tolhs-me24thiaz-leu-betaph 2926:tolhs-25thiaz-bala-betahbcph 2927:ibhs-ithiadiaz-gly-beta13bendi 2928:tolhs-ithiadiaz-gly-suabu 2929:bim-26py-ala-betapy 2930:ibhs-24thioph-bala-betacthioph 102931:ibhs-25thiaz-gly-betaet 2932:phhs-nme35pyr-gly-betaoxope 2933:bim-35fur-gly-betapy 2934:phhs-oxadiaz-gly-betafu2 2935:bhs-52thiaz-ala-betadcph 152936:tolhs-25methiaz-bala-betahmph 2937:ibhs-25thiaz-bala-betaftrif 2938:tolhs-oxadiaz-bala-zdap 2939:bim-me25thioph-ala-beta34meoph 2940:gua-42pym-gly-beta35dbph 202941:gua-26py-gly-betabpy 2942:4pmhs-25thiaz-gly-zdap 2943:tolhs-oxadiaz-gly-betaphethioa 2944:tolhs-nme35pyr-gly-betatbuph 2945:gua-26py-gly-betahbcph 25294fi:bhs-25thiaz-bala-betacthioph 2947:ibhs-24thioph-bala-suabu 2948:ibhs-24thiaz-gly-betacph 2949:ibhs-nme35pyr-gly-betaftrif 2950:2py-me25thiaz-gly-betadcph 302951:2py-24oxaz-ala-zdap 2952:agua-24thiaz-gly-betadcph 2953:impy-42nmeim-bala-betahb 2954:bhs-25oxaz-bala-betabdimo 2955:phhs-nme35pyr-bala-zdap 352956:bhs-me24thiaz-leu-zdap 2957:tolhs-24thiaz-bala-beta23meoph 2958:bhs-triaz-gly-betameph 2959:bhs-ithiadiaz-gly-betathio3 2960:ibhs-nme35pyr-bala-betafph 2961:gua-24thiaz-gly-betahni 2962:bhs-25thiaz-nmgly-betacthioph 2963:tolhs-25oxaz-bala-betadcphch 2964:phhs-25thiaz-bala-betafu3 2965:tolhs-ithiadiaz-bala-zdaptb 2966:ibhs-ithiadiaz-gly-betaipro 2967:bhs-25oxaz-ala-betaoxaz ' 2968:phhs-ithiadiaz-gly-betaipr 2969:bhs-nme35pyr-bafa-betabenfu 2970:2py-52thiaz-ala-psdap 2971:bhs-24thioph-gly-betabpy 2972:dhthi-25methiaz-bala-betadcph 2973:ibhs-24thioph-gly-betaomebendi 2974:tolhs-nme35pyr-gly-betadcphch 2975:bhs-25thiaz-bala-betaanaphth 2976:bhs-25methiaz-ala-betaoxaz 2977:tolhs-25methiaz-bala-betadmph 2978:2py-42nmeim-gly-betadcph 2979:bhs-35thioph-gly-betadcph 2980:phhs-nme35pyr-bala-betahmofu 2981:ibhs-25methiaz-gly-betahmph 2982:tolhs-ithiadiaz-gly-betapym 2983:bhs-ithiadiaz-gly-betadcphee 2984:bim-53pyrazo-bala-betadcph 2985:tolhs-25oxaz-bala-betabph 2986:ibhs-25oxaz-giy-betahph 2987:tolhs-25oxaz-gly-betampy 2988:ibhs-oxadiaz-bala-zdaptb 2989:bhs-oxadiaz-bala-betafbph 2990:tolhs-25oxaz-gly-betaipr 2991:bim-me24thioph-bala-beta34meoph 2992:bhs-42pym-gly-betadcph 2993:phhs-25methiaz-bala-betadtrif 2994:2py-25oxaz-gly-betaipr 2995:phhs-oxadiaz-bala-betacbph 2996:ibhs-24thioph-gly-betaoxaz 2997:tolhs-ithiadiaz-gly-betaftrif 2998:bhs-nme35pyr-nmgly-betaoxaz 2999:bhs-25thiaz-ala-betabnapbth 3000:phhs-24thioph-gly-betacbph 3001:bhs-me25thioph-leu-betapy 3002:bhs-me24thiaz-ala-betadcph 3003:ibhs-25thiaz-bala-betaol 3004:ibhs-25methiaz-gly-betabediox 103005:phhs-25thiaz-gly-betaipr 3006:bim-24oxaz-bala-zdap 3007:bhs-25oxaz-bala-zdapch 3008:3pmhs-25thiaz-bala-betapy 3009:tolhs-25methiaz-bala-betafluo 153010:bhs-ithiadiaz-gly-betapbiph 3011:phhs-24thiaz-gly-beta23meoph 3012:bhs-nme35pyr-gly-betadhbfu 3013:ibhs-25oxaz-bala-aspaba 3014:thpym-24thiaz-gly-betadcph 203015:bhs-oxadiaz-gly-betafbph 3016:2py-25thiaz-leu-psdap 3017:2py-53pyrazo-ala-psdap 3018:ibhs-nme35pyr-bala-beta23meoph 3019:tolhs-24thioph-gly-betahni 253020:ibhs-24thioph-gly-betamethioph 3021:bhs-25methiaz-bala-betahc 3022:phhs-oxadiaz-bala-betamethioph 3023:ibhs-25methiaz-bala-aspaba 3024:bim-24thioph-gly-betaomebendi 303025:tolhs-ithiadiaz-gly-betapytb 3026:bim-25methiaz-gly-betatrif 3027:2py-me25thiaz-gly-betaph 3028:phhs-25oxaz-bala-betabpy 3029:phhs-nme35pyr-gly-betahph 353030:tolhs-ithiadiaz-gly-betabmph 3031:tolhs-25methiaz-gly-betahni 3032:phhs-25methiaz-bala-betaomebendi 3033:tolhs-oxadiaz-gly-betamethi 3034:ibhs-24thiaz-bala-csdap 3035:ibhs-ithiadiaz-gly-betaomebendi 3036:tolhs-oxadiaz-bala-betamesu 3037:bhs-24thioph-gly-psdapch 3038:phhs-24thioph-gly-zdap 3039:2py-25oxaz-bala-psdap 3040:bhs-me24thiaz-ala-betapy 3041:tolhs-24thioph-bala-beta34dcph 3042:2py-25thioph-leu-betadcph 3043:bhs-25methiaz-gly-betafluo 3044:tolhs-25oxaz-gly-betahmph 3045:tolhs-nme35pyr-bala-betacbph 3046:ibhs-25thiaz-bala-betahni 3047:sabhs-25methiaz-gly-psdap 3048:ibhs-ithiadiaz-gly-zdapee 3049:ibhs-nme35pyr-gly-betafph 3050:bim-25thioph-bala-betadcph 3051:phhs-25oxaz-bala-betahph 3052:phhs-nme35pyr-bala-aspaba 3053:ibhs-24thioph-gly-beta4bph 3054:bhs-25thiaz-gly-betatrif 3055:bhs-25thiaz-bala-betathio3 3056:tolhs-ithiadiaz-gly-betathio3 3057:tolhs-ithiadiaz-bala-zdap 3058:bim-24thiaz-bala-betatos 3059:tolhs-25oxaz-gly-suabu 3060:bhs-24thioph-bala-betapbiph 3061:ibhs-oxadiaz-bala-betabnaphth 3062:bim-42nmeim-gly-zdap 3063:phhs-me25thiaz-leu-betapy 3064:bhs-25methiaz-gly-betamesu 3065:bhs-me25thiaz-gly-psdap 3066:tolhs-me25oxaz-bala-zdap 3067:bim-53pyrazo-ala-betapy 3068:phhs-ithiadiaz-bala-beta34dcph 3069:ibhs-25thiaz-gly-betapyee WO 00166618 PCTIEP00l03469 3070: tolhs-25thiaz-bala-betaoxope 3071: ibhs-25methiaz-gly-betampy 3072: tolhs-24thiaz-gly-betaoxope 3073: bhs-oxadiaz-gly-beta34meoph 3074: tolhs-ithiadiaz-bala-betaoxaz 3075: phhs-24thioph-gly-betadcphch 3076: 2py-me24thiaz-bala-psdap 3077: bhs-25thiaz-ala-betainyl 3078: phhs-25thiaz-gly-betahdcph 3079:phhs-25thiaz-gly-betah35dc 3080: tolhs-25methiaz-gly-betathio3 3081: 2py-me24thioph-gly-betaph 3082: bhs-24thioph-bala-betaoxope 3083: bhs-24thiaz-bala-aspbzla 3084:phhs-25thiaz-bala-betamethioph 3085: tolhs-25thiaz-bala-betadcphee 3086: bhs-24thioph-feu-betadcph 3087: ibhs-24thioph-gly-ibsdap 3088: phhs-nme35pyr-gly-betaibph 3089:phhs-25thiaz-bala-betahdbph 3090: bgua-24thiaz-gly-psdap 3091: bhs-25oxaz-gly-betadcph 3092: phhs-nme35pyr-bala-betaol 3093: tolhs-ithiadiaz-bala-betaibph 3094:phhs-25thiaz-bala-betacph 3095: ibhs-nme35pyr-bala-betabediox 3096: tolhs-ithiadiaz-gly-betapych 3097: bhs-nme35pyr-gly-psdap 3098: phhs-25thiaz-gly-betahb 3099:phhs-24thiaz-gly-betafu2 3100: tolhs-ithiadiaz-bala-betadcph 3101: ibhs-25oxaz-gly-betabph 3102: gua-24oxaz-gly-betapym 3103: tolhs-25thiaz-bala-betabediox 3104:bim-thiadiaz-bala-psdap 3105: tolhs-24thiaz-bala-betamethi 3106: bhs-24thioph-gly-betaol 3107: bim-25thioph-bala-psdap 3108: tolhs-25oxaz-gly-aspbzla 3109: tolhs-24thioph-bala-betaamibe 3110: bhs-me24thiaz-gly-betapy 3111: ibhs-oxadiaz-bala-betadmoph 3112: tolhs-25thiaz-bala-betabmph 3113: phhs-25thiaz-bala-betabmph 3114: phhs-25oxaz-bala-beta34meoph 3115: phhs-25methiaz-gly-asppha 103116: bhs-25methiaz-bala-betatrif 3117: bim-me24thiaz-leu-psdap 3118: ibhs-25thiaz-gly-betabdimo 3119: gua-25oxaz-gly-zdap 3120: bhs-25oxaz-gly-betahmph 153121: bim-42pym-gly-betapy 3122: ibhs-25thiaz-gly-psdaptb 3123: bhs-25oxaz-bala-beta4bph 3124: bhs-ithiadiaz-gly-betahcbph 3125: ibhs-25thiaz-bala-zdapch 203126: ibhs-nme35pyr-bala-busu2be 3127: bhs-24oxaz-ala-betadcph 3128: bhs-25methiaz-gly-betapyee 3129: ibhs-24thiaz-bala-betabph 3130: phhs-ithiadiaz-bala-betabnaphth 253131: ibhs-ithiadiaz-bala-zdapch 3132: bhs-nme35pyr-nmgly-betaipro 3133: bhs-25thiaz-bala-csdap 3134: tolhs-ithiadiaz-bala-betathiobe 3135: bhs-24thiaz-gly-betadcph 303136: dhim-25thiaz-gly-betadcph 3137: tolhs-25oxaz-bala-betatrif 3138: impy-24thioph-ala-betapy 3139: phhs-25methiaz-gly-betathio3 3140: gua-24thiaz-gly-betapyr 353141: impy-24thiaz-bala-betaftrif 3142: phhs-nme35pyr-bala-betahni 3143: 2py-42nmeim-bala-psdap WO 00!66618 PCTIEP00103469 3144: ibhs-25thiaz-bala-asppha 3145: phhs-24thioph-bala-psdapch 3146: tolhs-24thiaz-gly-betadmph 3147: bim-24thiaz-gly-betadbph 3148: bhs-42pym-gly-betapy 3149: phhs-25methiaz-bala-betafluo 3150: 2py-35thioph-ala-zdap 3151: tolhs-24thiaz-bala-betaoxaz 3152: phhs-24thioph-bala-betatos 3153:tolhs-oxadiaz-bala-beta23meoph 3154: bhs-ithiadiaz-nmgly-betabpy 3155: tolhs-nme35pyr-bala-betameph 3156: tolhs-ithiadiaz-gly-betacph 3157: bhs-24oxaz-ala-betapy 3158:2py-24thioph-bala-zdap 3159: bim-25thiaz-bala-betahcbph 3160: phhs-25thiaz-gly-betathiobe 3161: bhs-24thioph-bala-busu2be 3162: phhs-me25oxaz-bala-psdap 3163:phhs-25thiaz-gly-betatos 3164: bhs-25thiaz-nmgly-betabnaphth 3165: tolhs-24thioph-gly-betadcphtb 3166: ibhs-ithiadiaz-gly-betacph 3167: phhs-ithiadiaz-bala-betahph 3168:ibhs-ithiadiaz-bala-betaet 3169: phhs-25methiaz-bala-ibsdap 3170: tolhs-25methiaz-gly-betahdcph 3171: ibhs-25oxaz-bala-betahmofu 3172: bhs-24thioph-gly-betahmofu 3173:2py-me25oxaz-bala-betadcph 3174: bhs-nme35pyr-bala-betacthioph 3175: ibhs-24thioph-bala-betaipro 3176: bim-25methiaz-gly-betahmph 3177: sabhs-26py-gly-betainyl 3178:phhs-ithiadiaz-gly-psdapch 3179: bim-me25oxaz-bala-betaph 3180: phhs-oxadiaz-bala-betaphethioa 3181:tolhs-ithiadiaz-bala-betainyl 3182:bhs-24thioph-nmgly-betadhbfu 3183:phhs-25methiaz-gly-betaol 3184:phhs-ithiadiaz-bala-betabph 3185:2py-me25thioph-ala-zdap 3186:bim-ithiadiaz-bala-aspaba 3187:dhim-26py-nmgly-zdap 3188:2py-24thioph-ala-betapy 3189:tolhs-25oxaz-gly-betafu3 3190:tolhs-25oxaz-bala-betahdcph 3191:bhs-ithiadiaz-gly-betatbuph 3192:2py-25methiaz-bala-betahni 3193:bhs-24thiaz-ala-betaipro 3194:bhs-24thiaz-gly-aspaba 3195:ibhs-nme35pyr-bala-aspibua 3196:bhs-25methiaz-bala-betabmph 3197:bhs-25methiaz-ala-betamesu 3198:bhs-nme35pyr-bala-betadcph 3199:impy-42nmeim-bala-betapy 3200:ibhs-25methiaz-bala-betadbph 3201:ibhs-ithiadiaz-bala-asppha 3202:tolhs-25methiaz-bala-betatrif 3203:ibhs-ithiadiaz-bala-betapym 3204:bhs-nme35pyr-nmgly-betathioph 3205:tolhs-me25oxaz-bala-psdap 3206:tolhs-24thioph-bala-betatbuph 3207:bhs-ithiadiaz-bala-busu2be 3208:tolhs-oxadiaz-bala-aspibua 3209:phhs-ithiadiaz-gly-betafphe 3210:ibhs-25methiaz-gly-betahdbph 3211:bhs-me24oxaz-gly-psdap 3212:bhs-46pym-a1a-zdap 3213:bim-25thioph-ala-betainyl 3214:phhs-24thioph-gly-betampy 3215:gua-26py-gly-betaftrif 3216:ibhs-25thiaz-bala-betabmph 3217:ibhs-oxadiaz-gly-betadcph 3218:2pmhs-25methiaz-bala-betabmph 3219:bim-ithiadiaz-gly-asppha 3220:phhs-25methiaz-gly-beta34dcph 3221:tolhs-24thioph-gly-betahcbph 3222:bhs-ithiadiaz-nmgly-betafphe 3223:ibhs-ithiadiaz-gly-betaphethio 3224:phhs-25oxaz-bala-zdapch 3225:ibhs-oxadiaz-gly-betamesu 3226:tolhs-oxadiaz-bala-betadcphee 3227:tolhs-ithiadiaz-gly-aspaba 3228:impy-24thioph-bala-busu2be 3229:bhs-24thioph-leu-zdap 3230:ibhs-oxadiaz-bala-betaftrif 3231:gua-26py-gly-betapbiph 3232:ibhs-oxadiaz-gly-betapytb 3233:bim-25fur-gly-betadcph 3234:bhs-24thiaz-gly-psdaptb 3235:ibhs-ithadiaz-gly-beta34meoph 3236:tolhs-25thiaz-bala-betadcphch 3237:phhs-24thioph-bala-betahb 3238:2py-25thiaz-gly-psdap 3239:tolhs-24thiaz-gly-betahdbph 3240:ibhs-nme35pyr-gly-psdap 3241:bhs-25thiaz-leu-betameph 3242:bhs-25thiaz-bala-betafphe 3243:ibhs-oxadiaz-gly-beta34meoph 3244:phhs-me24oxaz-ala-zdap 3245:ibhs-ithiadiaz-gly-betabpy 3246:bhs-ithiadiaz-gly-betamethi 3247:phhs-25thiaz-bala-csdap 3248:bhs-25thiaz-met-betadcph 3249:2py-nme35pyr-bala-psdap 3250:bhs-25thiaz-gly-betatos 3251:bhs-25oxaz-gly-betaomebendi 3252:bhs-24thiaz-gly-betapyee 3253:ibhs-oxadiaz-bala-betafphe 3254:gua-24thiaz-nmgly-betapy WO 00!66618 PCTIEPOOl03469 3255:ibhs-24thiaz-bala-psdapee 3256:2py-25methiaz-bala-aspaba 3257:ibhs-25thiaz-gly-betabediox 3258:phhs-me24thiaz-leu-beta34meoph 3259:ibhs-25methiaz-bala-betabthioph 3260:ibhs-25oxaz-gly-betapych 3261:2py-52thiaz-ala-betainyl 3262:tolhs-me24thioph-ala-zdap 3263:ibhs-24thioph-gly-betabmph 3264:bhs-25thiaz-gly-zdaptb 3265:phhs-24thioph-bala-ibsdap 3266:bhs-nme35pyr-gly-betahni 3267:bhs-25oxaz-gly-zdapch 3268:phhs-25oxaz-gly-betafu3 3269:phhs-25thiaz-bala-betadmoph 3270:bhs-oxadiaz-nmgly-betadmoph 3271:bhs-25methiaz-gly-betahbcph 3272:tolhs-25methiaz-bala-betabthioph 3273:bhs-oxadiaz-bala-zdapch 3274:gua-24oxaz-gly-betaamibe 3275:phhs-25thiaz-gly-betabpy 3276:bhs-24im-bala-psdap 3277:phhs-24thiaz-bala-asppha 3278:ibhs-ithiadiaz-gly-betadmoph 3279:tolhs-24thioph-bala-suabu 3280:bim-me24oxaz-bala-betadcph 3281:tolhs-oxadiaz-bala-betabph 3282:phhs-24thiaz-bala-betaipro 3283:bhs-oxadiaz-bala-betaipro 3284:phhs-25oxaz-bala-betadtrif 3285:ibhs-25oxaz-gly-betambiph 3286:bhs-nme35pyr-gly-aspibua 3287;bim-oxadiaz-leu-betapy 3288:bhs-oxadiaz-ala-betaanaphth 3289:2py-25thiaz-ala-betainyl 3290:2py-24thiaz-bala-suabu 3291:bhs-24thiaz-bala-betahni 3292:bhs-25methiaz-ser-betapy 3293:phhs-oxadiaz-gly-betaheph 3294.gua-24thiaz-gly-suabu 3295:tolhs-25methiaz-bala-betacph 3296:ibhs-25thiaz-gly-betapy 3297:ibhs-24thioph-bala-betatos 3298:thpym-24thiaz-gly-betahdcph 3299:tolhs-25methiaz-bala-aspibua 3300:thazep-25oxaz-gly-psdap 3301:tolhs-nme35pyr-bala-zdapch 3302:bhs-oxadiaz-gly-betaphethioa 3303:phhs-me24thioph-leu-betaph 3304:phhs-me25oxaz-gly-psdap 3305:tolhs-25methiaz-gly-betamethi 3306:ibhs-25oxaz-bala-betacbph 3307:bhs-25thiaz-leu-betapy 3308:ibhs-ithiadiaz-gly-betahdcph 3309:they-24oxaz-gly-betadcph 3310:phhs-25thiaz-bala-betathioph 3311:bim-ithiadiaz-gly-aspaba 3312:tolhs-ithiadiaz-bala-aspbzla 3313:bim-24thioph-ala-zdap 3314:ibhs-25oxaz-gly-betapyr 3315:bhs-24thioph-gly-betaipro 3316:bhs-24thiaz-bala-betaoxope 3317:bhs-nme35pyr-gly-betah35dc 3318:phhs-oxadiaz-bala-betapym 3319:tolhs-24thiaz-bala-betaheph 3320:ibhs-ithiadiaz-gly-betaheph 3321:phhs-24thioph-gly-betaomebendi 3322:ibhs-ithiadiaz-bala-betacthioph 3323:bhs-ithiadiaz-gly-betamesu 3324:nmhs-24thioph-gly-betadcph 3325:ibhs-24thiaz-bala-betatrif 3326:bhs-oxadiaz-bala-betambiph 3327:bhs-oxadiaz-nmgly-betaipro 3328:bim-me24thioph-leu-beta34meoph WO 00!66618 PCTlEP00/03469 3329:2pmhs-24thiaz-gly-betahbcph 3330:tolhs-24thiaz-gly-betapy 3331:ibhs-25oxaz-bala-betathiobe 3332:2pmhs-42pym-gly-betapy 3333:phhs-25methiaz-bala-betaph 3334:phhs-oxadiaz-gly-betafphe 3335:tolhs-ithiadiaz-gly-betahmo 3336:bhs-25oxaz-nmgly-betathioph 3337;bhs-42nmeim-gly-suabu 3338:ibhs-24thiaz-bala-betah35dc 3339;bgua-24thioph-gly-betameph 3340:phhs-ithiadiaz-gly-betatos 3341:tolhs-oxadiaz-giy-beta34dcph 3342:ibhs-25methiaz-bala-betaheph 3343:bim-25fur-ala-zdap 3344:bim-24thioph-bala-betadcph 3345:ibhs-25oxaz-bala-betaftrif 3346:ibhs-oxadiaz-gly-beta34dcph 3347:tolhs-25thiaz-gly-betamesu 3348:bhs-oxadiaz-bala-betapy 3349:impy-24thioph-bala-betaphethioa 3350:ibhs-24thioph-giy-betadcph 3351:bhs-ithiadiaz-gly-aspibua 3352:bhs-24oxaz-bala-zdap 3353:tolhs-25thiaz-gly-betapytb 3354:phhs-oxadiaz-bala-betabenfu 3355:tolhs-24thiaz-bala-betahcbph 3356:bim-25thiaz-bala-betacph 3357:ibhs-25methiaz-bala-betatbuph 3358:tolhs-25thiaz-bala-betabthioph 3359:phhs-ithiadiaz-bala-betathio3 3360:ibhs-24thioph-bala-busu2be 3361:2py-53pyrazo-ala-betadcph 3362:tolhs-oxadiaz-gly-beta35dbph 3363:ibhs-ithiadiaz-bala-betahc 3364:phhs-oxadiaz-bala-betapytb 3365:phhs-oxadiaz-gly-betafbph 3366: tolhs-me24oxaz-gly-betadcph 3367: bhs-25oxaz-bala-betapytb 3368: phhs-24thiaz-gly-betahdbph 3369: bim-26py-ala-betainyl 3370: phhs-24thioph-gly-betambiph 3371: bhs-nme35pyr-gly-betambiph 3372: bhs-ithiadiaz-bala-betamesu 3373: tolhs-nme35pyr-giy-psdapch 3374: bhs-25oxaz-nmgly-betabpy 3375: tolhs-me24thioph-ala-betapy 3376: phhs-24thiaz-gly-betameph 3377: phhs-25oxaz-giy-betaol 3378: bim-24thioph-bala-betahc 3379: bhs-nme35pyr-ala-betabpy 3380: ibhs-24thiaz-gly-betadhbfu 3381: bhs-25oxaz-gly-betahbcph 3382: tolhs-me24oxaz-leu-betaph 3383: 4pmhs-26py-gly-betapy 3384: ibhs-25thiaz-bala-betahbcph 3385: tolhs-24thiaz-bala-betadcph 3386: tolhs-oxadiaz-bala-betainyl 3387: tolhs-25methiaz-bala-psdap 3388: phhs-me24thioph-bala-betadcph 3389: phhs-oxadiaz-bala-betathio3 3390: phhs-24thioph-bala-asppha 3391: bhs-24thioph-bala-betainyl 3392: bhs-25oxaz-gly-betatluo 3393: ibhs-nme35pyr-bala-psdapee 3394: bim-me25oxaz-leu-betadcph 3395: tolhs-ithiadiaz-bala-betafu2 3396: phhs-25methiaz-gly-betabthioph 3397: bhs-24thiaz-bala-betafbph 3398: ibhs-nme35pyr-bala-betafluo 3399: bhs-ithiadiaz-nmgly-betal3bendi 3400: bhs-24thiaz-gly-betaol 3401: ibhs-oxadiaz-gly-suabu 3402: nmhs-42nmeim-gly-psdap 3403:phhs-25methiaz-bala-asppha 3404:gua-26py-gly-beta34dcph 3405:phhs-ithiadiaz-bala-betadbph 3406:phhs-me25thioph-gly-psdap 3407:bhs-24thiaz-bala-betabediox 3408:bim-25thioph-ala-betadcph 3409:bhs-ithiadiaz-ala-ibsdap 3410:ibhs-25thiaz-bala-aspibua 3411:bhs-24thioph-bala-beta4bph 3412:ibhs-ithiadiaz-bala-betabnaphth 3413:2py-25methiaz-gly-betathio3 3414:bhs-ithiadiaz-gly-betampy 3415:phhs-nme35pyr-gly-betamethi 3416:ibhs-24thioph-bala-beta34meoph 3417:ibhs-25oxaz-bala-betafu3 3418:phhs-ithiadiaz-gly-betaimid 3419:tolhs-25oxaz-gly-betadcphch 3420:tolhs-24thioph-bala-betafbph 3421:ibhs-25thiaz-bala-betatbuph 3422:bhs-25oxaz-gly-psdaptb 3423:bim-me24thioph-bala-betaph 3424:bhs-24thiaz-gly-beta3quin 3425:bim-me24thiaz-leu-betadcph 3426:phhs-ithiadiaz-gly-beta13bendi 3427:tolhs-25methiaz-giy-aspibua 3428:tolhs-24thiaz-gly-betadhbfu 3429:bhs-42pym-ala-betadcph 3430:ibhs-nme35pyr-bala-betacthoph 3431:bhs-25oxaz-gly-betaanaphth 3432:ibhs-ithiadiaz-gly-betatos 3433:ibhs-nme35pyr-bala-betadcph 3434:ibhs-nme35pyr-bala-betatos 3435:tolhs-nme35pyr-bala-betahbcph 3436:2py-me25thioph-ala-betaph 3437:ibhs-oxadiaz-gly-busu2be 3438:bim-triaz-bala-zdap 3439:bhs-24thioph-gly-betampy WO 00166618 PCTlEP00103469 3440:bhs-35fur-bala-betapy 3441:bhs-me24thioph-leu-beta34meoph 3442:ibhs-25oxaz-bala-betaanaphth 3443:bhs-25oxaz-leu-zdap 3444:gua-24thiaz-gly-betadmoph 3445:bhs-ithiadiaz-bala-betacthioph 3446:bhs-25thiaz-gly-betapyr 3447:ibhs-ithiadiaz-gly-beta34dcph 3448:tolhs-oxadiaz-bala-betaheph 3449:tolhs-oxadiaz-gly-betapyee 3450:gua-24oxaz-gly-betambiph 3451:tolhs-24thioph-gly-betafu3 3452:tolhs-24thiaz-bala-zdaptb 3453:tolhs-ithiadiaz-gly-betaoxope 3454:phhs-nme35pyr-gly-betaftrif 3455:bhs-ithiadiaz-bala-betadcphtb 3456:bim-triaz-bala-psdap 3457:bhs-nme35pyr-gly-betapyr 3458:bhs-25oxaz-bala-betaipro 3459:tolhs-nme35pyr-gly-betabmph 3460:ibhs-24thiaz-bala-betadmph 3461:tolhs-24thiaz-gly-betaphethio 3462:agua-26py-gly-betadcph 3463:2py-triaz-gly-psdap 3464:2py-24thiaz-bala-betabnaphth 3465;tolhs-oxadiaz-bala-betaph 3466:ibhs-25methiaz-gly-aspaba 3467:bim-me24thiaz-gly-betaph 3468:bim-me24thioph-ala-betapy 3469:ibhs-24thiaz-bala-betaanaphth 3470:bim-42nmeim-ala-betapy 3471:ibhs-24thioph-bala-betahni 3472:bhs-24thioph-bala-asppha 3473:ibhs-24thiaz-bala-betahph 3474:bhs-25oxaz-bala-betahc 3475:tolhs-24thioph-gly-betah35dc 3476:bim-me24thioph-ala-beta34meoph 3477:bim-me25oxaz-bala-beta34meoph 3478:tolhs-25thiaz-bala-aspaba 3479:ibhs-oxadiaz-bala-betampy 3480:bhs-35thioph-ala-betapy 3481:tolhs-24thioph-bala-betafph 3482:bhs-nme35pyr-bala-ibsdap 3483:2pmhs-24thioph-bala-betapyr 3484:phhs-24thiaz-gly-betafphe 3485:bhs-25oxaz-bala-betacbph 3486:tolhs-24thioph-gly-zdaptb 3487:bim-me24thiaz-leu-betapy 3488:bim-ithiadiaz-leu-betapy 3489:ibhs-ithiadiaz-bala-beta34dcph 3490:bhs-oxadiaz-bala-csdap 3491:phhs-25methiaz-bala-aspbzla 3492:2py-me24oxaz-gly-psdap 3493:bhs-24thioph-gly-csdap 3494:phhs-ithiadiaz-bala-betadcphch 3495:ibhs-nme35pyr-gly-asppha 3496:bhs-oxadiaz-gly-betaftrif 3497:bhs-25methiaz-bala-betabenfu 3498:gua-24thiaz-gly-betaomebendi 3499:bhs-me25thiaz-gly-beta34meoph 3500:bim-25methiaz-bala-betampy 3501:phhs-25oxaz-gly-betaphethio 3502:tolhs-24thiaz-gly-zdap 3503:bhs-nme35pyr-bala-betacph 3504:tolhs-nme35pyr-gly-betabdimo 3505:bhs-nme35pyr-bala-betadcphch 3506:bhs-25thiaz-bala-betabnaphth 3507:bhs-25thiaz-bala-betaph 3508:tolhs-oxadiaz-gly-betatrif 3509:2py-me24oxaz-leu-beta34meoph 3510:tolhs-ithiadiaz-bala-betathiome 3511:tolhs-25thiaz-bala-betapych 3512:tolhs-25oxaz-gly-betabediox 3513:tolhs-25methiaz-bala-betapym WO 00!66618 PCTIEP00103469 3514:bhs-25thiaz-gly-betambiph 3515:phhs-ithiodiaz-bala-betaoxaz 3516:2py-42oxaz-bala-betadcph 3517:bhs-nme35pyr-gly-psdapee 3518:gua-24oxaz-gly-betafph 3519:phhs-24thioph-bala-betafphe 3520:bhs-25thiaz-bala-betapytb 3521:phhs-24thiaz-bala-betadcphch 3522:phhs-25thiaz-bala-betapyr 103523:tolhs-nme35pyr-gly-psdaptb 3524:tolhs-nme35pyr-bala-suabu 3525:bhs-42oxaz-bala-betadcph 3526:phhs-25methiaz-gly-betapych 3527:impy-25methiaz-bala-betainyl 153528:phhs-25thiaz-gly-ibsdap 3529:phhs-25oxaz-gly-betabnaphth 3530:bhs-oxadiaz-gly-betatos 3531:tolhs-25thiaz-gly-betambiph 3532:bhs-25methiaz-bala-psdaptb 203533:impy-24thiaz-gly-betathiobe 3534:bhs-25methiaz-bala-betamethioph 3535:bhs-25thiaz-nmgly-betainyl 3536:bhs-ithiadiaz-bala-betadito 3537:gua-24thiaz-gly-betabenfu 253538:ibhs-24thiaz-bala-betadtrif 3539:phhs-me25thioph-leu-betapy 3540:phhs-me25thiaz-gly-betaph 3541:ibhs-ithiadiaz-gly-betabnaphth 3542:ibhs-25oxaz-gly-betahbcph 303543:bhs-25thiaz-nmgly-beta3quin 3544:impy-24thioph-gly-betahmofu 3545:bhs-24thioph-gly-betapym 3546:2py-52thiaz-gly-zdap 3547:phhs-oxadiaz-bala-betaibph 353548:2pmhs-25methiaz-bala-beta4bph 3549:tolhs-25methiaz-gly-betaet 3550:bhs-25thiaz-ala-betahmph 3551: bhs-25thioph-leu-betapy 3552: bhs-25methiaz-gly-suabu 3553: phhs-oxadiaz-bala-suabu 3554: phhs-25thiaz-bala-psdap 3555: phhs-me24thioph-leu-psdap 3556: bim-24thioph-gly-betaibph 3557: ibhs-oxadiaz-gly-betapy 3558: tolhs-24thiaz-bala-betaanaphth 3559: phhs-oxadiaz-bala-betaoxope 103560: bhs-24thiaz-bala-betapyee 3561: ibhs-24thiaz-gly-betahb 3562: tolhs-oxadiaz-bala-betahdbph 3563: bhs-24thiaz-gly-betabph 3564: bhs-ithiadiaz-ala-beta34dcph 153565: ibhs-24thiaz-bala-betatbuph 3566: ibhs-24thiaz-gly-betaipro 3567: bhs-ithiadiaz-ala-betadcph 3568: bhs-25thiaz-bala-betafbph 3569: phhs-25oxaz-gly-zdapch 203570: ibhs-24thiaz-gly-betabediox 3571: ibhs-25methiaz-gly-betadmoph 3572: phhs-24thioph-gly-betaipr 3573: bhs-ithiadiaz-bala-betabph 3574: tolhs-nme35pyr-gly-psdapee 253575: bim-42oxaz-bala-psdap 3576: ibhs-25oxaz-bala-betafluo 3577: tolhs-nme35pyr-gly-betahmo 3578: bhs-25methiaz-bala-aspaba 3579: bhs-25thioph-gly-zdap 303580: phhs-25oxaz-gly-betadmph 3581: bhs-oxadiaz-bala-betapyr 3582: gua-26py-gly-betamethioph 3583: 2py-25thioph-bala-betapy 3584: bhs-oxadiaz-ala-betathioph 353585: bim-thiadiaz-bala-zdap 3586: bim-25oxaz-bala-betamethioph 3587: bhs-25methiaz-nmgly-betamesu 3588:dhpyrr-26py-gly-betadcph 3589:2py-me25thiaz-gly-beta34rneoph 3590:phhs-oxadiaz-giy-betahcbph 3591:2py-me25thioph-gly-beta34meoph 3592:phhs-25methiaz-gly-betaibph 3593:ibhs-nme35pyr-bala-betamesu 3594:ibhs-24thioph-bala-betabpy 3595:ibhs-24thioph-bala-betadcphee 3596:ibhs-oxadiaz-gly-betacthioph 3597:gua-24oxaz-gly-betathiome 3598:gua-42pym-gly-betaoxope 3599:2py-25oxaz-gly-aspbzla 3600:bhs-oxadiaz-gly-betadhbfu 3601:phhs-25methiaz-bala-betacthioph 3602:bim-25methiaz-bala-betaipro 3603:jbhs-ithiadiaz-gly-betadito 3604:tolhs-nme35pyr-bala-betahdbph 3605:bim-me24thioph-gly-beta34meoph 3606:phhs-me24thioph-gly-betapy 3607:bhs-35fur-leu-psdap 3608:ibhs-24thiaz-gly-betadmph 3609:dhim-24thiaz-gly-betainyl 3610:bhs-42oxaz-gly-betadcph 3611:ibhs-24thiaz-bala-betaet 3612:phhs-nme35pyr-gly-betahb 3613:gua-24thiaz-gly-betabpy 3614:2py-52thiaz-gly-psdap 3615:tolhs-25methiaz-bala-suabu 3616:phhs-25oxaz-gly-betabdimo 3617:bhs-nme35pyr-nmgly-betadmph 3618:ibhs-oxadiaz-gly-betadmoph 3619:phhs-nme35pyr-gly-aspaba 3620:phhs-nme35pyr-bala-betamesu 3621:bhs-25thiaz-bala-betathiobe 3622:bhs-24thiaz-leu-psdap 3623:bhs-25thiaz-gly-betadtrif 3624:ibhs-25methiaz-gly-betapyee 3625: bim-35thioph-gly-psdap 3626: bhs-25oxaz-gly-betadtrif 3627: bhs-oxadiaz-bala-betadcph 3628: bim-25thiaz-ala-betapy 3629: 2py-24thiaz-gly-asppha 3630: bhs-oxadiaz-gly-betaamibe 3631: bhs-ithiadiaz-nmgly-beta34dcpth 3632: bim-24thiaz-gly-betameph 3633: phhs-me24oxaz-gly-psdap 3634:bim-me24thiaz-gly-psdap 3635: bhs-oxadiaz-gly-betaheph 3636: thpy-24thioph-gly-betadcph 3637: gua-25thioph-gly-betaoxope 3638: bhs-42pym-gly-betameph 3639:bhs-24thiaz-gly-betafu2 3640: tolhs-25oxaz-gly-betaheph 3641: bhs-25oxaz-nmgly-betahmph 3642: impy-25oxaz-gly-betapym 3643: gua-25thiaz-gly-betamethi 3644:phhs-oxadiaz-bala-betacthioph 3645: bhs-24thioph-gly-betaibph 3646: phhs-25methiaz-bala-betahmofu 3647: bhs-25oxaz-gly-betacthioph 3648: bhs-oxadiaz-bala-betaipr 3649:phhs-24thioph-gly-betaamibe 3650: phhs-nme35pyr-gly-betaamibe 3651: phhs-25methiaz-gly-betaphethio 3652: phhs-25thiaz-gly-betapbiph 3653: ibhs-25oxaz-gly-betapy 3654:tolhs-nme35pyr-gly-aspibua 3655: ibhs-24thiaz-gly-psdapch 3656: 2py-35fur-ala-psdap 3657: tolhs-24thiaz-bala-betaomebendi 3658: ibhs-25methiaz-bala-betadhbfu 3659:ibhs-25methiaz-bala-betaoxaz 3660: bim-25methiaz-gly-asppha 3661: phhs-ithiadiaz-bala-betadmoph WO 0016661$ PCTIEP00103469 3662:bhs-35fur-ala-betadcph 3663:phhs-25thiaz-bala-betatos 3664:bim-42nmeim-gly-betafu3 3665:bhs-24thioph-gly-beta35dbph 3666:ibhs-nme35pyr-bala-betadhbfu 3667:cima-24thiaz-bala-psdap 3668:tolhs-25methiaz-bala-betaol 3669:gua-26py-gly-betaipr 3670:tolhs-ithiadiaz-bala-betaipr 103671:ibhs-nme35pyr-gly-csdap 3672:tolhs-24thiaz-gly-betafph 3673:phhs-25methiaz-bala-betaphethio 3674:phhs-ithiadiaz-bala-betafphe 3675:tolhs-24thioph-bala-beta23meoph 153676:phhs-25thiaz-bala-aspbzla 3677:tolhs-oxadiaz-gly-betacbph 3678:bhs-24thiaz-ala-betabnaphth 3679:phhs-25methiaz-bala-betapbiph 3680:2py-24im-ala-psdap 203681:tolhs-24thiaz-bala-betathiobe 3682:pbhs-oxadiaz-giy-betaphethio 3683:tolhs-25oxaz-gly-betahbcph 3684:tolhs-oxadiaz-bala-betacbph 3685:tolhs-25oxaz-gly-beta34meoph 253686:bhs-25oxaz-gly-betathiome 3687:dhim-42nmeim-gly-zdap 3688:ibhs-ithiadiaz-gly-betabthioph 3689:ibhs-oxadiaz-gly-betaet 3690:bhs-25methiaz-nmgly-beta34dcph 303691:ibhs-25oxaz-gly-beta23meoph 3692:phhs-25methiaz-gly-betacph 3693:ibhs-nme35pyr-gly-betathio3 3694:bim-me24thiaz-gly-betadcph 3695:phhs-24thioph-gly-csdap 353696:ibhs-nme35pyr-bala-asppha 3697:2py-me24thioph-ala-psdap 3698:tolhs-25oxaz-gly-zdapee WO 00166618 PCTlEP00103469 3699: dhim-26py-gly-psdap 3700: 2py-25thioph-bala-zdap 3701: tolhs-25oxaz-bala-psdapch 3702: phhs-24thioph-gly-zdapch 3703: bim-thiadiaz-bala-betadcph 3704: bim-24oxaz-bala-betadcph 3705: tolhs-25oxaz-gly-psdap 3706: bim-52thiaz-gly-zdap 3707: ibhs-oxadiaz-baia-betadito 103708: bhs-me24thiaz-bala-zdap 3709: 2py-ithiadiaz-bala-asppha 3710: gua-42pym-gly-betafu2 3711: phhs-25methiaz-bala-betaanaphth 3712: bhs-26py-ala-zdap 153713: ibhs-24thiaz-gly-betaoxope 3714: phhs-24thioph-bala-betadcphee 3715: dhim-52thiaz-ala-betainyl 3716: phhs-ithiadiaz-bala-betaanaphth 3717: bhs-24thioph-gly-betafph 203718: gua-24thiaz-gly-betahb 3719: bhs-oxadiaz-gly-betaipro 3720: phhs-25methiaz-gly-betatrif 3721: bim-me24thioph-gly-zdap 3722: ibhs-oxadiaz-bala-betaoxaz 253723: gua-24thiaz-gly-betacbph 3724: ibhs-ithiadiaz-gly-betahni 3725: bim-ithiadiaz-bala-aspibua 3726: 2py-42oxaz-gly-betadcph 3727: tolhs-ithiadiaz-gly-betaet 303728: ibhs-25methiaz-bala-betahdcph 3729: 2py-42nmeim-gly-betacph 3730: tolhs-oxadiaz-bala-betaanaphth 3731: phhs-ithiadiaz-gly-betaanaphth 3732: phhs-ithiadiaz-gly-betafluo 353733: tolhs-ithiadiaz-bala-betaftrif 3734: phhs-oxadiaz-gly-betaet 3735: phhs-24thiaz-bala-csdap 3736: ibhs-25oxaz-bala-psdap 3737: 2pmhs-25oxaz-gly-betaol 3738: tolhs-oxadiaz-gly-betadcph 3739: phhs-24thioph-bala-betamesu 3740: bhs-25thiaz-gly-betadito 3741: 2py-42pym-ala-betainyl 3742: tolhs-me25oxaz-gly-zdap 3743: 2pmhs-25oxaz-gly-beta3quin 3744: phhs-24thiaz-bala-betahmo 103745: tolhs-24thiaz-bala-csdap 3746: bhs-26py-gly-betapy 3747: bim-53pyrazo-leu-betapy 3748: 2py-25methiaz-gly-zdap 3749: ibhs-nme35pyr-gly-betadtrif 153750: dhim-42pym-ala-betadcph 3751: ibhs-nme35pyr-bala-zdaptb 3752: bim-25thiaz-gly-betadbph 3753: tolhs-25oxaz-bala-betahrnph 3754: tolhs-25methiaz-bala-betahph 203755: ibhs-ithiadiaz-gly-betapyr 3756: bhs-ithiadiaz-ala-betaipro 3757: ibhs-25methiaz-bala-psdapch 3758: phhs-nme35pyr-bala-zdapee 3759: bim-me25thiaz-bala-beta34meoph 253760: tolhs-oxadiaz-bala-betahdcph 3761: phhs-oxadiaz-gly-betampy 3762: ibhs-oxadiaz-gly-betathiome 3763: impy-2thioph-gly-betapy 3764: bhs-25oxaz-gly-betainyl 303765: ibhs-25thiaz-bala-betafph 3766: tolhs-ithiadiaz-gly-betafphe 3767: hts-42pym-gfy-betapy 3768: ibhs-24thiaz-gly-betahmph 3769: phhs-nme35pyr-bala-betapyee 353770: tolhs-nme35pyr-gly-beta34meoph 3771: bim-me25thioph-bala-betaph 3772: tolhs-24thiaz-bala-betadmph 3773:bhs-ithiadiaz-gly-betaamibe 3774:bhs-25thioph-leu-psdap 3775:bhs-me25thiaz-leu-betaph 3776:bhs-25methiaz-bala-csdap 3777:tolhs-25thiaz-gly-beta4bph 3778:bhs-24thioph-nmgly-betainyl 3779:phhs-oxadiaz-gly-betabenfu 3780:phhs-nme35pyr-gly-psdaptb 3781:gua-24thiaz-gly-betatos 3782:tolhs-oxadiaz-gly-betabdimo 3783:bhs-25thiaz-gly-betafluo 3784:bhs-triaz-ala-psdap 3785:bhs-35pyrazo-gly-betapy 3786:2pmhs-24thiaz-bala-betapyr 3787:tolhs-25methiaz-bala-betaphethioa 3788:bhs-24thiaz-bala-betahdbph 3789:ibhs-25thiaz-gly-betadcphee 3790:phhs-24thioph-bala-betadito 3791:phhs-oxadiaz-gly-betabdimo 3792:2py-24thiazme-gly-betapy 3793:ibhs-nme35pyr-gly-beta34meoph 3794:phhs-ithiadiaz-gly-betahbcph 3795:ibhs-oxadiaz-gly-betaibph 3796:2py-24thioph-bala-psdap 3797:2pmhs-25oxaz-bala-suabu 3798:bhs-24thioph-nmgly-betabpy 3799:ibhs-oxadiaz-bala-asppha 3800:gua-25thiaz-gly-betaomebendi 3801:3pmhs-42pym-gfy-betapy 3802:tolhs-25thiaz-gly-suabu 3803:ibhs-24thioph-bala-betafu2 3804:tolhs-oxadiaz-bala-psdapch 3805:ibhs-oxadiaz-bala-betadcphtb 3806:phhs-ithiadiaz-bala-betaftrif 3807:ibhs-oxadiaz-gly-betaoxope 3808:2py-oxadiaz-bala-psdap 3809:tolhs-me25oxaz-gly-psdap WO 00!66618 PCTlEP00103469 3810:bhs-25methiaz-nmgly-beta13bendi 3811:tolhs-24thiaz-bala-betabpy 3812:hs-42pym-gly-betapy 3813:tolhs-25oxaz-bala-betapbiph 3814:ibhs-oxadiaz-bala-beta34meoph 3815:bhs-ithiadiaz-ala-betameph 3816:phhs-me24oxaz-leu-beta34meoph 3817:bhs-25thiaz-nmgly-betafphe 3818:tolhs-ithiadiaz-gly-betafluo 103819:tolhs-25thiaz-bala-betamethi 3820:bhs-24thioph-nmgly-betathio3 3821:bhs-24thiaz-hphe-betapy 3822:tolhs-25methiaz-bala-aspbzla 3823:bim-me25thiaz-ala-betadcph 153824:bhs-25thiaz-bala-asppha 3825:bhs-nme35pyr-gly-betamesu 3826:ibhs-ithiadiaz-gly-betapyee 3827:phhs-25oxaz-bala-betabnaphth 3828:ibhs-24thioph-gly-betadmoph 203829:phhs-ithiadiaz-gly-betabnaphth 3830:tolhs-nme35pyr-gly-beta3quin 3831:bhs-me25thioph-bala-betapy 3832:tolhs-nme35pyr-bala-betapym 3833:bhs-nme35pyr-ala-beta3quin 253834:ibhs-25oxaz-gly-betamethioph 3835:tolhs-25thiaz-gly-betaoxaz 3836:phhs-ithiadiaz-bala-betadcphee 3837:tolhs-24thiaz-bala-betaphethioa 3838:2py-25oxaz-gly-betadcph 303839:tolhs-oxadiaz-bala-betampy 3840:2py-42oxaz-leu-betapy 3841:ibhs-24thiaz-gly-zdaptb 3842:phhs-ithiadiaz-bala-psdaptb 3843:phhs-nme35pyr-gly-betafluo 353844:bhs-nme35pyr-gly-zdapee 3845:ibhs-24thioph-bala-betaoxaz 3846:ibhs-24thiaz-bala-betaoxaz WO 00!66618 PCTIEP00103469 3847: thazep-25thiaz-gly-beta13bendi 3848: bhs-24thioph-ala-betabnaphth 3849: bhs-ithiadiaz-nmgly-betamesu 3850: phhs-oxadiaz-giy-betacph 3851: ibhs-25methiaz-bala-betapyr 3852: 2py-25methiaz-gly-betaol 3853: tolhs-25methiaz-gly-betahbcph 3854: ibhs-25thiaz-bala-betadmph 3855: phhs-25thiaz-gly-beta35dbph 3856:ibhs-25thiaz-gly-csdap 3857: phhs-25thiaz-gly-betamethioph 3858: 2py-24thiaz-gly-betathio3 3859; ibhs-ithiadiaz-bala-betahni 3860: gua-25thioph-gly-betathio3 3861:bhs-oxadiaz-gly-beta34dcph 3862: dhim-25thiophme-ala-betameph 3863: ibhs-nme35pyr-bala-betahdcph 3864: tolhs-nme35pyr-bala-betathio3 3865: bhs-24thioph-gly-betacthioph 3866:phhs-25thiaz-bala-betaol 3867: ibhs-24thiaz-gly-ibsdap 3868: bhs-me24im-gly-betameph 3869: tolhs-24thiaz-giy-betabnaphth 3870: tolhs-me25thiaz-bala-zdap 3871:2py-35fur-bala-zdap 3872; tolhs-oxadiaz-bala-betabthioph 3873: bhs-ithiadiaz-gly-betahph 3874: bgua-25methiaz-gly-betameph 3875: phhs-ithiadiaz-bala-betabediox 3876:phhs-25methiaz-bala-betadcph 3877: ibhs-nme35pyr-gly-betapbiph 3878: tolhs-25methiaz-gly-betabenfu 3879: bim-25thiaz-bala-psdap 3880: bhs-25methiaz-gly-betaet 3881:phhs-me25thioph-bala-psdap 3882: tolhs-25thiaz-gly-betaoxope 3883: toihs-ithiadiaz-gly-betafu2 3884:ibhs-oxadiaz-bala-betabpy 3885:bim-25methiaz-gly-aspaba 3886:ibhs-nme35pyr-bala-betaamibe 3887:bhs-25methiaz-bala-betainyl 3888:bhs-ithiadiaz-gly-psdapee 3889:bgua-25oxaz-bala-betapy 3890:phhs-25methiaz-gly-betamesu 3891:phhs-25methiaz-bala-betaftrif 3892:ibhs-25thiaz-bala-betaanaphth 3893:ibhs-oxadiaz-bala-beta3quin 3894:phhs-25methiaz-bala-zdapch 3895:phhs-nme35pyr-bala-ibsdap 3896:2pmhs-25methiaz-bala-betathioph 3897:bhs-me24thiaz-leu-betapy 3898:phhs-25thiaz-bala-betathiome 3899:tolhs-25thiaz-gly-betapbiph 3900:gua-25thioph-gly-betahmo 3901:bim-25thioph-bala-betapy 3902:tolhs-oxadiaz-bala-beta35dbph 3903:tolhs-ithiadiaz-gly-aspbzla 3904:tolhs-nme35pyr-bala-betacthioph 3905:bhs-triaz-gly-psdap 3906:ibhs-oxadiaz-bala-betadhbfu 3907:phhs-me25oxaz-leu-zdap 3908:tolhs-oxadiaz-gly-betamethioph 3909:bhs-25oxaz-bala-betadbph 3910:bhs-oxadiaz-bala-betameph 3911:phhs-24thiaz-gly-aspaba 3912:bim-25thiaz-bala-betaimid 3913:2py-24thioph-leu-betadcph 3914:ibhs-25oxaz-gly-betaanaphth 3915:ibhs-nme35pyr-gly-betapyr 3916:tolhs-24thioph-gly-beta35dbph 3917:2pmhs-25methiaz-bala-betapyr 3918:tolhs-25thiaz-gly-betadmph 3919:2py-25methiaz-leu-betapy 3920:bhs-oxadiaz-bala-asppha 3921:bhs-25oxaz-gly-betahb 3922:tolhs-24thioph-bala-betameph 3923:phhs-me25oxaz-leu-beta34meoph 3924:2py-42nmeim-bala-betapy 3925:phhs-me25thiaz-ala-betapy 3926:phhs-25methiaz-bala-betampy 3927:ibhs-25oxaz-bala-suabu 3928:bhs-oxadiaz-gly-betabmph 3929:bhs-25oxaz-bala-betambiph 3930:tolhs-nme35pyr-gly-aspbzla 3931:ibhs-nme35pyr-gly-betapych 3932:ibhs-24thiaz-gly-betaph 3933:bhs-24thiaz-bala-betacthioph 3934:bhs-me25oxaz-leu-beta34meoph 3935:bhs-25oxaz-bala-betahbcph 3936:tolhs-25oxaz-bala-betafbph 3937:tolhs-25methiaz-bala-betabmph 3938:bhs-nme35pyr-nmgly-betadhbfu 3939:phhs-25methiaz-bala-betahni 3940:bhs-24thioph-bala-beta34meoph 3941:2py-24thioph-gly-betadito 3942:bhs-25oxaz-gly-betahph 3943:bhs-25methiaz-gly-psdaptb 3944:ibhs-nme35pyr-gly-betapym 3945:ibhs-ithiadiaz-gly-betadmph 3946:bim-24im-leu-zdap 3947:impy-25thiaz-gly-beta34meoph 3948:ur-42pym-ala-psdap 3949:bhs-ithiadiaz-bala-betafbph 3950:bhs-24thiaz-gly-betatos 3951:ibhs-24thioph-gly-zdapee 3952:tolhs-25methiaz-bala-betadcphtb 3953:ibhs-ithiadiaz-bala-betahmo 3954:ibhs-nme35pyr-bala-betahb 3955:phhs-25oxaz-gly-betaet 3956:ibhs-24thiaz-gly-betathio3 3957:bhs-25methiaz-gly-betahmph WO 00166618 PCTlEP00103469 3958:bhs-42oxaz-ala-psdap 3959:gua-25thiaz-gly-betapy 3960:ibhs-nme35pyr-bala-betahbcph 3961:phhs-nme35pyr-bala-betathiome 3962:bim-25methiaz-bala-psdap 3963:bhs-24thiaz-ala-betadmph 3964:phhs-25methiaz-gly-betathiome 3965:phhs-me25thioph-bala-betadcph 3966:bhs-ithiadiaz-bala-betathiome 3967:bhs-nme35pyr-bala-betathioph 3968:bim-24thioph-bala-betaimid 3969:phhs-24thioph-gly-betaftrif 3970:bhs-25thiaz-gly-betadcph 3971:phhs-me25thioph-gly-betaph 3972:bim-25methiaz-ala-betapy 3973:bhs-24thioph-ala-betathio3 3974:ibhs-24thiaz-bala-aspbzla 3975:phhs-oxadiaz-bala-betahmph 3976:bhs-ithiadiaz-ala-betaanaphth 3977:bhs-25oxaz-gly-aspaba 3978:bhs-ithiadiaz-gly-betaol 3979:2py-thiadiaz-leu-betadcph 3980:phhs-me25oxaz-bala-betapy 3981:ibhs-25oxaz-gly-beta34dcph 3982:ibhs-oxadiaz-gly-betabmph 3983:bhs-oxadiaz-bala-beta4bph 3984:tolhs-24thiaz-bala-betafu3 3985:bhs-25oxaz-bala-betafu2 3986:tolhs-me25thiaz-ala-psdap 3987:tolhs-25oxaz-bala-betamesu 3988:2py-26py-gly-betahdcph 3989:bhs-25methiaz-met-betadcph 3990:bhs-me25oxaz-bala-beta34meoph 3991:bim-me24thioph-gly-betaph 3992:bhs-25oxaz-gly-betaibph 3993:phhs-oxadiaz-gly-betahdbph 3994:tolhs-me25oxaz-ala-betadcph 3995: 2py-25fur-gly-zdap 3996: bim-thiadiaz-leu-betapy 3997: tolhs-24thiaz-bala-betathioph 3998: 2py-24thioph-gly-betathio3 3999: bhs-24thiaz-gly-betahmo 4000: phhs-nme35pyr-gly-betabenfu 4001: ibhs-25thiaz-bala-betapych 4002: bhs-24oxaz-ala-zdap 4003: impy-24thiaz-bala-betamethi 104004: ibhs-oxadiaz-gly-betaphethio 4005: tolhs-25thiaz-bala-betaet 4006: phhs-25methiaz-bala-betahmph 4007: phhs-oxadiaz-bala-betadito 4008: bim-25fur-ala-betadcph 154009: tolhs-oxadiaz-bala-beta34meoph 4010: bhs-24thioph-ala-betamesu 4011: phhs-25thiaz-gly-betadmoph 4012: bhs-nme35pyr-ala-betaipro 4013: tolhs-25thiaz-gly-betabpy 204014: ibhs-nme35pyr-gly-betaipr 4015: bhs-25methiaz-gly-betabmph 4016: tolhs-25oxaz-bala-betapych 4017: tolhs-oxadiaz-gly-csdap 4018: tolhs-nme35pyr-bala-beta35dbph 254019: 2py-me25thioph-leu-beta34meoph 4020: phhs-oxadiaz-bala-betahni 4021: ibhs-24thioph-bala-betadmph 4022: bhs-25methiaz-gly-betadito 4023: bhs-42nmeim-ala-betadcph 304024: ibhs-25oxaz-bala-betaphethioa 4025: bim-me24thiaz-bala-zdap 4026: bhs-42py-gly-betameph 4027: tolhs-24thioph-gly-betahmph 4028: bim-me24thioph-ala-zdap 354029: bim-me25thiaz-gly-beta34meoph 4030: bhs-25thiaz-bala-betabthioph 4031: bim-25thiaz-gly-aspaba WO 00166618 PCTIEP0010346g 4032: gua-24thiaz-gly-betafbph 4033: thpym-42pym-gly-betahcbph 4034: bhs-nme35pyr-bala-betaamibe 4035: bhs-25oxaz-gly-betapbiph 4036: phhs-25thiaz-gly-betahc 4037: 2py-nme35pyr-bala-aspibua 4038: bim-24oxaz-gly-betadcph 4039: phhs-24thioph-gly-betahbcph 4040: 2py-me25thioph-leu-betapy 104041: bhs-me25thioph-ala-psdap 4042: bhs-me25oxaz-leu-betapy 4043: tolhs-ithiadiaz-bala-betahmofu 4044: 2py-25th iaz-bala-betabn aphth 4045: bim-24thiaz-gly-betadmph 154046: ibhs-24thiaz-gly-betaol 4047: tolhs-25thiaz-gly-betafbph 4048: bhs-42nmeim-bala-betapy 4049: phhs-25methiaz-gly-betahb 4050: phhs-25thiaz-bala-betacbph 204051: tolhs-nme35pyr-gly-zdapee 4052: phhs-ithiadiaz-bala-zdaptb 4053: thazep-25thiaz-bala-zdap 4054: 2py-24chin-gly-betapy 4055: ibhs-25methiaz-gly-betapytb 254056: bhs-25thiaz-bala-betadcphtb 4057: phhs-25methiaz-bala-beta13bendi 4058: tolhs-24thiaz-gly-betapbiph 4059: bhs-ithiadiaz-gly-betaipr 4060: 2py-35thioph-gly-zdap 304061: phhs-me25thiaz-gly-zdap 4062: ibhs-24thioph-bala-betadcph 4063: tolhs-25oxaz-gly-betambiph 4064: bhs-nme35pyr-gly-betahmph 4065: bhs-25methiaz-ala-psdap 354066: tolhs-25thiaz-bala-betafph 4067: tolhs-ithiadiaz-gly-betabph 4068: tolhs-nme35pyr-bala-aspaba WO 00166618 PCTIEP00l03469 4069:2py-42oxaz-ala-zdap 4070:ibhs-nme35pyr-bala-betadcphch 4071:2py-24thiaz-ala-betameph 4072:2py-24thiaz-gly-betaol 4073:ibhs-25methiaz-bala-betapych 4074:2pmhs-24thiaz-gly-betadtrif 4075:dhim-26pyrazi-gly-betameph 4076:tolhs-24thiaz-gly-betadcph 4077:ibhs-nme35pyr-bala-betapym 4078:ibhs-25methiaz-bala-betahb 4079:bhs-24thioph-bala-betadcph 4080:ibhs-oxadiaz-gly-betapyee 4081:bhs-25thiaz-gly-aspibua 4082:bim-me25thiaz-leu-betadcph 4083:phhs-25methiaz-bala-betatos 4084:phhs-me25thiaz-ala-psdap 4085:bhs-25methiaz-ala-ibsdap 4086:bim-52thiaz-ala-betadcph 4087:phhs-24thiaz-bala-betambiph 4088:phhs-ithiadiaz-gly-beta3quin 4089:bhs-24thioph-gly-betapbiph 4090:2py-25oxaz-bala-betaftrif 4091:bhs-oxadiaz-ala-betameph 4092:tolhs-oxadiaz-bala-betaoxaz 4093:ibhs-oxadiaz-bala-betaibph 4094:bhs-24thiaz-gly-betaph 4095:ibhs-nme35pyr-gly-betafbph 4096:tolhs-nme35pyr-gly-betaanaphth 4097:phhs-24thiaz-gly-betamesu 4098:bhs-25oxaz-ala-betadcph 4099:tolhs-ithiadiaz-bala-betaimid 4100:impy-25oxaz-gly-betabph 4101:dhim-42pym-gly-betadtrif 4102:2py-me25thioph-bala-betapy 4103:ibhs-24thioph-gly-betadtrif 4104:2py-me24thioph-bala-beta34meoph 4105:bhs-25thiaz-nmgly-ibsdap WO 00166618 PCTlEP00103469 4106: phhs-nme35pyr-bafa-betahmo 4107: phhs-25oxaz-gly-betaheph 4108: gua-42pym-gly-betainyl 4109: gua-42pym-gly-betaomebendi 4110: bhs-25thiaz-bala-betahbcph 4111: tolhs-25oxaz-bala-betabthioph 4112: bhs-nme35pyr-nmgly-betahrnph 4113: ibhs-25oxaz-gly-betadmoph 4114: tolhs-nme35pyr-bala-betabmph 104115: tolhs-nme35pyr-bala-betapbiph 4116: bhs-25oxaz-bafa-betahdcph 4117: impy-24thioph-bala-betamethi 4118: bim-me24oxaz-gly-beta34meoph 4119: phhs-me25oxaz-ala-betapy 154120: bim-me24thioph-gly-psdap 4121: bhs-24thioph-gly-betahph 4122: phhs-24thioph-gly-betaol 4123: ibhs-25thiaz-bala-zdaptb 4124: tolhs-nme35pyr-gly-betaamibe 204125: bhs-24thiaz-bala-betahb 4126: bhs-24thiaz-gly-zdapch 4127: gua-42pym-gly-betapyr 4128: phhs-oxadiaz-gly-zdapee 4129: bim-25thiaz-ala-psdap 254130: bhs-ithiadiaz-gly-betapy 4131: bhs-25methiaz-gly-betacph 4132: ibhs-25oxaz-gly-betaet 4133: 2py-42py-gly-betapy 4134: 2py-25oxaz-gly-betapy 304135: bhs-oxadiaz-gly-betafph 4136: ibhs-24thioph-gly-beta3quin 4137: tolhs-25oxaz-bala-betadcphee 4138: 2py-me25oxaz-ala-psdap 4139: bhs-24thioph-nmgly-betadito 354140: bhs-nme35pyr-gly-betahdcph 4141: bhs-oxadiaz-bala-betamethi 4142: bhs-nme35pyr-gly-betadcphee 4143:bhs-25methiaz-bala-betaibph 4144:bhs-24thioph-bala-beta23meoph 4145:ibhs-oxadiaz-bala-betatos 4146:tolhs-ithiadiaz-bala-betadtrif 4147:bhs-oxadiaz-gly-betapych 4148:tolhs-ithiadiaz-bala-betaamibe 4149:bhs-24thiaz-bala-betadbph 4150:bhs-24thioph-bala-betaphethioa 4151:phhs-25oxaz-bala-betadcphch 1D4152:tolhs-24thiaz-gly-betafluo 4153:phhs-25methiaz-gly-betaimid 4154:tolhs-oxadiaz-gly-betadtrif 4155:bhs-nme35pyr-ala-betadmph 4156:bim-25thiaz-bala-betampy 154157:phhs-25methiaz-bala-betathioph 4158:phhs-nme35pyr-gly-zdapch 4159:bhs-25methiaz-gly-betatos 4160:tolhs-25oxaz-bala-betahc 4161:2py-me24thiaz-ala-beta34meoph 204162:tolhs-me24thioph-gly-beta34meoph 4163:bim-oxadiaz-gly-betadcph 4164:ibhs-25thiaz-bala-betapbiph 4165:bhs-25thiaz-bala-betatos 4166:2py-25methiaz-bala-betapy 254167:tolhs-25methiaz-bala-zdapch 4168:gua-42pym-gly-betafluo 4169:bhs-nme35pyr-bala-betaphethioa 4170:tolhs-24thioph-bala-psdapee 4171:phhs-25oxaz-gly-ibsdap 304172:ibhs-25thiaz-gly-betabnaphth 4173:2py-25thiaz-gly-beta35dbph 4174:ibhs-oxadiaz-gly-betaimid 4175:bhs-me25thioph-ala-betapy 4176:phhs-24thioph-gly-betathioph 354177:ibhs-24thiaz-gly-betaomebendi 4178:bim-25fhiaz-ala-zdap 4179:ibhs-25methiaz-bala-betahmph 4180: ibhs-24thioph-gly-betahbcph 4181: bim-25oxaz-gly-betahbcph 4182: bhs-ithiadiaz-g1y-betadito 4183: bhs-24thioph-nmgly-betaipro 4184: bim-35thioph-ala-zdap 4185: ibhs-25oxaz-gly-betadcphch 4186: phhs-24thiaz-bala-zdapee 4187: bhs-me24thiaz-bala-betaph 4188: bim-nme35pyr-ala-zdap 4189:tolhs-25thiaz-gly-betaomebendi 4190: bhs-24thioph-gly-psdapee 4191: tolhs-nme35pyr-bala-zdap 4192: tolhs-nme35pyr-gly-aspaba 4193: ibhs-oxadiaz-bala-betatbuph 4194:tolhs-25oxaz-gly-betameph 4195: 2py-thiadiaz-bala-betadcph 4196: bim-24im-gly-betapy 4197: phhs-24thioph-gly-betadtrif 4198: bhs-nme35pyr-bala-betabph 4199:2py-24thioph-bala-aspibua 4200: bhs-25methiaz-bala-betafbph 4201: bhs-24thiaz-bala-betaibph 4202: impy-25thiaz-nmgly-psdap 4203: phhs-oxadiaz-gly-betatos 4204:phhs-24thioph-gly-betal3bendi 4205: bim-triaz-leu-betadcph 4206: phhs-25methiaz-bala-csdap 4207: phhs-nme35pyr-gly-betainyl 4208: ibhs-nme35pyr-bala-beta4bph 4209:phhs-ithiadiaz-bala-betahni 4210: 2py-24th iaz-ala-psdap 4211: tolhs-25thiaz-bala-beta4bph 4212: bhs-25thiaz-gly-beta34dcph 4213: bhs-25thiaz-bala-betafu3 4214:phhs-24thioph-gly-beta35dbph 4215: phhs-24thiaz-gly-betadmoph 4216: bhs-oxadiaz-ala-beta13bendi 4217: 2pmhs-25oxaz-bala-betafluo 4218: phhs-25oxaz-gly-zdaptb 4219: phhs-24thiaz-bala-betamesu 4220: ibhs-24thioph-gly-betaph 4221: tolhs-nme35pyr-gly-betafphe 4222: bhs-25methiaz-gly-betabthioph 4223: bhs-25thiaz-bala-psdap 4224: tolhs-25methiaz-gly-betaibph 4225: bhs-me25oxaz-leu-betadcph 4226:2pmhs-25oxaz-bata-beta34dcph 4227: 2pmhs-24thiaz-bala-betabmph 4228: bim-24im-ala-betapy 4229: phhs-25thiaz-gly-betathio3 4230: ibhs-nme35pyr-gly-betahbcph 4231:tolhs-25oxaz-bala-betaol 4232: phhs-nme35pyr-bala-zdapch 4233: phhs-24thiaz-gly-betacph 4234: ibhs-24thioph-gly-betamethi 4235: 2pmhs-25thiaz-gly-betabpy 4236:phhs-24thioph-bala-zdapee 4237: phhs-oxadiaz-bala-betapyee 4238: ibhs-24thioph-gly-csdap 4239: tolhs-oxadiaz-bala-betapyr 4240: bim-25thiaz-bala-aspibua 4241:bhs-oxadiaz-gly-ibsdap 4242: bim-53pyrazo-leu-betadcph 4243: bhs-ithiadiaz-bala-betafu3 4244: tolhs-ithiadiaz-bala-betambiph 4245: ibhs-25methiaz-bala-betabdimo 4246:impy-25thiaz-gly-betathiobe 4247: bhs-oxadiaz-gly-betaanaphth 4248: tolhs-25thiaz-bala-betahdbph 4249: bhs-oxadiaz-bala-betathio3 4250: bhs-25fur-leu-betadcph 4251:2py-me25thioph-ala-betadcph 4252: phhs-24thioph-bala-betamethi 4253: 2pmhs-25oxaz-gly-psdap 4254: bhs-oxadiaz-gly-betahmo 4255: phhs-nme35pyr-bala-aspbzla 4256: nmhs-25thiaz-gly-betadcph 4257: bhs-24thiaz-ala-betadmoph 4258: impy-25thiaz-bala-psdap 4259: bim-24oxaz-gly-betapy 4260: bhs-25oxaz-gly-suabu 4261: bim-25thioph-gly-betapy 4262: bim-25methiaz-bala-aspibua 104263: bhs-oxadiaz-gly-betahdcph 4264: ibhs-24thiaz-bala-betacthioph 4265: tolhs-24thiaz-gly-betaamibe 4266: tolhs-24thioph-bala-beta3quin 4267: ibhs-25thiaz-bala-betamesu 154268: phhs-oxadiaz-bala-zdapee 4269: ibhs-24thiaz-bala-betahmofu 4270: bhs-25methiaz-bala-betaet 4271: ibhs-25thiaz-gly-betaheph 4272: ibhs-24thiaz-bala-beta34meoph 204273: ibhs-nme35pyr-bala-betathioph 4274: bhs-25methiaz-bala-betafluo 4275: bim-25oxaz-ala-betapy 4276: phhs-24thioph-bala-betapbiph 4277: tolhs-24thiaz-gly-betadito 254278: bim-42oxaz-ala-psdap 4279: bhs-24thiophme-gly-zdap 4280: tolhs-24thiaz-bala-betadcphtb 4281: bhs-25thiaz-bala-betabpy 4282: phhs-me25oxaz-leu-betaph 304283: phhs-nme35pyr-gly-beta3quin 4284: bhs-oxadiaz-bala-betabthioph 4285: bim-nme35pyr-bala-aspibua 4286: bhs-25thiaz-bala-betaphethio 4287: ibhs-25thiaz-bala-betaoxaz 354288: bhs-nme35pyr-gly-zdaptb 4289: ibhs-25oxaz-bala-busu2be 4290: bhs-25methiaz-nmgly-betadmoph 4291: tolhs-oxadiaz-bala-betameph 4292: bhs-24thiaz-gly-betabiph 4293: ibhs-25rnethiaz-bala-betapym 4294: tolhs-nme35pyr-gly-betathioph 4295:tolhs-25methiaz-bala-psdapch 4296: 2py-25thiaz-gly-asppha 4297: tolhs-24thiaz-bala-betahc 4298: 2pmhs-25thioph-gly-betapy 4299: ibhs-24thiaz-bala-betaph 4300:impy-25methiaz-bala-betamethi 4301: phhs-oxadiaz-gly-betathiobe 4302: ibhs-25thiaz-gly-betathioph 4303: gua-25thiaz-gly-betacthioph 4304: phhs-24thioph-gly-beta3quin 4305:phhs-oxadiaz-bala-betafph 4306: phhs-ithiadiaz-bala-betaoxope 4307; tolhs-25methiaz-bala-betahdcph 4308: bhs-24oxaz-leu-psdap 4309: ibhs-24thiaz-bala-betahdcph 4310:gua-24thiaz-gly-betahc 4311: phhs-24thiaz-bala-betadbph 4312: 2pmhs-25oxaz-gly-betatbuph 4313: ibhs-24thioph-bala-psdap 4314: bim-24thioph-bala-betapy 4315:tolhs-24thiaz-gly-beta13bendi 4316: pahs-25thiaz-gly-betapy 4317: thazep-24thiaz-bala-zdap 4318: phhs-24thioph-gly-betameph 4319; impy-24thioph-gly-betaipr 4320;2py-42nmeim-bala-betatrif 4321: phhs-24thiaz-gly-psdapee 4322: phhs-oxadiaz-gly-beta35dbph 4323: thpym-24thiaz-gly-betacbph 4324: phhs-24thiaz-bala-zdap 4325:ibhs-24thioph-bala-betapyee 4326: tolhs-ithiadiaz-gly-betaipro 4327: bhs-26py-gly-zdap WO 00166618 f~CTIEP00103469 4328:phhs-ithiadiaz-bala-beta13bendi 4329:ibhs-25methiaz-gly-betaheph 4330:bhs-nme35pyr-gly-betacph 4331:bhs-thiadiaz-leu-zdap 4332:tolhs-24thiaz-gly-betafu3 4333:2py-ithiadiaz-leu-psdap 4334:thpym-42pym-gly-beta35dbph 4335:bhs-35fur-leu-zdap 4336:bim-me25thiaz-ala-psdap 4337:bim-thiadiaz-bala-betapy 4338:bhs-25thiaz-bala-betadcphee 4339:ibhs-ithiadiaz-bala-betadhbfu 4340:phhs-24thiaz-bala-betafu2 4341:bhs-oxadiaz-bala-aspibua 4342:tolhs-25thiaz-gly-betamethioph 4343:bhs-25oxaz-nmgly-betadhbfu 4344:3pmhs-24thiaz-bala-betapy 4345:2py-42pym-ala-zdap 4346:tolhs-24thioph-gly-betaoxaz 4347:phhs-25oxaz-bala-betaimid 4348:bim-25oxaz-bala-aspibua 4349:phhs-nme35pyr-gly-betathiobe 4350:ibhs-24thioph-bala-betahc 4351:bhs-nme35pyr-bala-zdapee 4352:2py-24thiaz-bala-betaoxope 4353:bhs-25thiaz-ala-betamesu 4354:phhs-25methiaz-bala-betah35dc 4355:bhs-25oxaz-gly-betacbph 4356:tolhs-25thiaz-gly-beta3quin 4357:bhs-oxadiaz-gly-betadbph 4358:tolhs-25oxaz-bala-betameph 4359:phhs-24thiaz-gly-beta4bph 4360:2py-me25thiaz-leu-betadcph 4361:2py-nme35pyr-gly-betapy 4362:bhs-25oxaz-bala-betacph 4363:bhs-25methiaz-bala-betal3bendi 4364:dhim-25thiaz-gly-psdap 4365:2py-42nmeim-bala-betadbph 4366:bhs-ithiadiaz-gly-betapytb 4367:phhs-ithiadiaz-bala-betatos 4368:tolhs-oxadiaz-bala-betafu3 4369:2py-24thiaz-gly-aspbzla 4370:bhs-25oxaz-bala-betaibph 4371:ibhs-ithiadiaz-gly-betahb 4372:ibhs-25thiaz-bala-betadcph 4373:ibhs-24thiaz-gly-beta23meoph 104374:tolhs-nme35pyr-bala-betatbuph 4375:bhs-24thioph-bala-betapyr 4376:ibhs-nme35pyr-gly-betahcbph 4377:bhs-53pyrazo-gly-psdap 4378:pahs-24thiaz-bala-betameph 154379:ibhs-oxadiaz-gly-betabpy 4380:tolhs-nme35pyr-gly-betatrif 4381:phhs-25thiaz-bala-betabdimo 4382:ibhs-25oxaz-bala-betaheph 4383:tolhs-24thiaz-gly-betaibph 204384:2py-triaz-ala-betapy 4385:bhs-25methiaz-gly-betadmph 4386:phhs-25thiaz-bala-betaibph 4387:ibhs-25thiaz-giy-betahcbph 4388:phhs-oxadiaz-bala-beta35dbph 254389:bim-nme35pyr-ala-psdap 4390:phhs-25oxaz-bala-betahmofu 4391:bim-25thiaz-bala-betatos 4392:ibhs-25oxaz-bala-psdapee 4393:hts-24thioph-gly-betapy 304394:bhs-25methiaz-bala-beta4bph 4395:bhs-me25thiaz-gly-betapy 4396:bhs-25methiaz-gly-betaibph 4397:bhs-25oxaz-bala-betaanaphth 4398:bhs-25thiaz-gly-betaphethio 354399:phhs-24thiaz-bala-beta23meoph 4400:tolhs-24thiaz-gly-csdap -4401:phhs-oxadiaz-gly-betaol WO 00!66618 PCTIEP00103469 4402:ibhs-nme35pyr-gly-aspibua 4403:pahs-25oxaz-gly-betapy 4404:bhs-oxadiaz-bala-beta13bendi 4405:phhs-24thioph-gly-betatbph 4406:ibhs-25thiaz-gly-betaimid 4407:bhs-oxadiaz-nmgly-betabnaphth 4408:phhs-25oxaz-gly-betainyl 4409:bim-ithiadiaz-gly-aspbzla 4410:tolhs-24thioph-gly-betacph 104411:bhs-nme35pyr-gly-betaphethio 4412:2py-42oxaz-gly-betapy 4413:ibhs-24thiaz-bala-betamesu 4414:bhs-24thioph-bala-betahb 4415:tolhs-oxadiaz-bala-betahph 154416:bhs-nme35pyr-bala-betapytb 4417:tolhs-24thiaz-gly-betahc 4418:bim-35thioph-leu-betadcph 4419:bhs-25methiaz-bala-betahmo 4420:bim-me25thioph-gly-beta34meoph 204421:4pmhs-25thiaz-gly-betapy 4422:phhs-25thiaz-bala-betahmph 4423:phhs-25methiaz-gly-aspbzla 4424:gua-24thiaz-gly-betacthioph 4425:thpym-25thioph-gly-betacbph 254426:dhim-25thiaz-gly-betapy 4427:ibhs-25methiaz-bala-zdap 4428:bhs-25methiaz-bala-busu2be 4429:bim-24thioph-gly-betahmph 4430:phhs-nme35pyr-gly-betaipro 304431:bhs-me24oxaz-ala-beta34meoph 4432:bhs-nme35pyr-ala-betacthioph 4433:bim-42oxaz-afa-betapy 4434:bhs-24thioph-gly-betadmph 4435:phhs-25methiaz-gly-betahbcph 354436:tolhs-24thioph-gly-betathiobe 4437:ibhs-25oxaz-bala-betaoxaz 4438:ibhs-nme35pyr-bala-betameph 4439: tolhs-ithiadiaz-gly-betapbiph 4440: bim-24thioph-bala-aspbzla 4441: 2py-nme35pyr-leu-betapy 4442: dhthi-24oxaz-gly-betapy 4443: tolhs-24thioph-gly-betadmph 4444: phhs-25thiaz-bala-psdaptb 4445: 2py-me25oxaz-gly-beta34meoph 4446: tolhs-oxadiaz-gly-betapyr 4447: bhs-24thiaz-gly-betamethi 104448: bhs-24thiaz-bala-betaph 4449: bhs-oxadiaz-bala-betahdcph 4450: gua-25thioph-gly-betahcbph 4451: 2py-52thiaz-gly-betainyl 4452: tolhs-oxadiaz-bala-betacthioph 154453: 2py-25methiaz-gly-betadcph 4454: bhs-oxadiaz-gly-betatrif 4455: tolhs-24thioph-gly-betabmh 4456: tolhs-25methiaz-bala-betadcph 4457: bim-triaz-ala-betadcph 204458: bhs-nme35pyr-gly-beta3quin 4459: phhs-24thioph-gly-betahb 4460: phhs-25thiaz-gly-betafbph 4461: impy-42nmeim-bala-betadtrif 4462: phhs-24thiaz-bala-suabu 254463: tolhs-24thioph-bala-betapyr 4464: bhs-25thiaz-ala-betadmoph 4465: bhs-25thiaz-bala-betah35dc 4466: hts-24thiaz-gly-betapy 4467: phhs-ithiadiaz-bala-betahdcph 304468: ibhs-24thiaz-bala-betamethioph 4469: bim-oxadiaz-gly-psdap 4470: bim-oxadiaz-leu-zdap 4471: ibhs-oxadiaz-gly-ibsdap 4472: tolhs-me24thioph-leu-beta34meoph 354473: phhs-ithiadiaz-bala-aspaba 4474: ibhs-oxadiaz-bala-betah35dc 4475: phhs-25methiaz-bala-betapych 4476:phhs-24thioph-gly-betabph 4477:impy-25thiaz-gly-betambiph 4478:bhs-25thiaz-gly-betafu2 4479:ibhs-oxadiaz-gly-psdapee 4480:bhs-24thioph-bala-betaimid 4481:tolhs-24thioph-gly-psdap 4482:ibhs-oxadiaz-bala-psdapch 4483.phhs-24thiaz-gly-betabthioph 4484:bim-26py-gly-betadcph 4485:bhs-24thioph-bala-betahmph 4486:ibhs-25oxaz-gly-betafphe 4487:bhs-25oxaz-gly-betaipr 4488:tolhs-24thiaz-gly-betahdcph 4489:gua-24oxaz-gly-betahmofu 4490:tolhs-24thioph-bala-betacph 4491:tolhs-24thioph-gly-beta34meoph 4492:bhs-oxadiaz-bala-beta35dbph 4493:phhs-ithiadiaz-gly-betaet 4494:bim-24thioph-bala-csdap 4495:bhs-25methiaz-gly-zdaptb 4496:bhs-nme35pyr-bala-betaphethio 4497:ibhs-24thiaz-gly-betathioph 4498:tolhs-24thiaz-bala-betapych 4499:tolhs-oxadiaz-gly-betadcphch 4500:bhs-ithiadiaz-leu-betadcph 4501:phhs-nme35pyr-gly-betaimid 4502:tolhs-24thiaz-gly-betahni 4503:2py-26py-gly-csdap 4504:bhs-triaz-bala-zdap 4505:tolhs-25oxaz-bala-betapyee 4506:phhs-oxadiaz-gly-betabediox 4507:bhs-25thiaz-gly-betapy 4508:tolhs-ithiadiaz-bala-beta23meoph 4509:gua-26py-gly-betambiph 4510:2pmhs-24thioph-gly-betameph 4511:phhs-oxadiaz-bala-betaipro 4512:tolhs-nme35pyr-gly-betaimid 4513.tolhs-nme35pyr-gly-beta34dcph 4514:phhs-25thiaz-bala-betabpy 4515:2py-24thioph-gly-psdap 4516:ibhs-24thioph-gly-betadcphch 4517:phhs-25methiaz-gly-betafphe 4518:tolhs-25methiaz-bala-betambiph 4519:tolhs-24thiaz-bala-betatrif 4520:phhs-oxadiaz-gly-betahc 4521:bim-oxadiaz-bala-zdap 4522:phhs-25methiaz-bala-betahb 4523:phhs-25methiaz-gly-zdapee 4524:bim-25thiaz-gly-betadmph 4525:phhs-25oxaz-gly-betatbuph 4526:phhs-25oxaz-gly-zdapee 4527:bhs-nme35pyr-ala-betahmph 4528:2py-me24thiaz-ala-zdap 4529:tolhs-ithiadiaz-bala-betahdbph 4530:ibhs-24thiaz-gly-zdapee 4531:tolhs-25methiaz-bala-betadcphee 4532:phhs-nme35pyr-bala-betaanaphth 4533:bhs-nme35pyr-bala-betaanaphth 4534:tolhs-nme35pyr-gly-betathiome 4535:ibhs-25methiaz-gly-betacthioph 4536:bhs-24thioph-gly-betah35dc 4537:bim-24oxaz-ala-psdap 4538:ibhs-oxadiaz-gly-betadcphee 4539:tolhs-oxadiaz-bala-betaol 4540:ibhs-ithiadiaz-bala-aspbzla 4541:2 py-26 py-ala-zd a p 4542:tolhs-oxadiaz-gly-betafu3 4543:bhs-me24thioph-leu-zdap 4544:dhpyrr-24oxaz-gly-betameph 4545:bhs-24thiaz-gly-psdap 4546:tolhs-oxadiaz-bala-betambiph 4547:phhs-24thioph-gly-betafphe 4548:tolhs-ithiadiaz-bala-betacbph 4549:phhs-24thiaz-bala-betadcphee WU 00/66618 PCTlEP00103469 4550:ibhs-25oxaz-gly-betampy 4551:phhs-oxadiaz-bala-aspaba 4552:bim-25oxaz-bala-betapyr 4553:phhs-25oxaz-bala-beta35dbph 4554:ibhs-25thiaz-bala-ibsdap 4555:ibhs-nme35pyr-gly-betaoxope 4556:tolhs-oxadiaz-gly-betabpy 4557:phhs-nme35pyr-bala-beta3quin 4558:tolhs-nme35pyr-gly-betamesu 104559:bhs-24thiaz-bala-betacph 4560:ibhs-nme35pyr-bala-betaheph 4561:2pmhs-24thioph-bala-beta4bph 4562:bhs-thiadiaz-bala-betapy 4563:phhs-nme35pyr-bala-betadbph 154564:2py-26py-gly-betapy 4565:bim-me24thioph-ala-psdap 4566:tolhs-me24thioph-ala-betaph 4567:phhs-24thioph-bala-betacthioph 4568:phhs-ithiadiaz-bala-betapym 204569:bhs-24thiaz-bala-betatrif 4570:phhs-25thiaz-bala-betaimid 4571:bhs-24thiaz-bala-betaet 4572:2pmhs-24thioph-bala-beta13bendi 4573:2py-me24thiaz-leu-psdap 254574:tolhs-24thioph-bala-betaph 4575:ibhs-25oxaz-gly-betahmo 4576:phhs-nme35pyr-bala-betapytb 4577:tolhs-ithiadiaz-gly-betadmph 4578:tolhs-ithiadiaz-gly-betahmofu 304579:phhs-24thioph-bala-betahcbph 4580:phhs-25rnethiaz-gly-beta4bph 4581:phhs-nme35pyr-bala-betafluo 4582:tolhs-24thiaz-gly-betah35dc 4583:ibhs-25methiaz-gly-betaet 354584:ibhs-25methiaz-bala-betabmph 4585:tolhs-25oxaz-gly-betahph 4586:bhs-ithiadiaz-nmgly-betameph 4587: ibhs-ithiadiaz-bala-ibsdap 4588: 2pmhs-25thiaz-bala-zdap 4589: bhs-25oxaz-gly-beta3quin 4590: ibhs-ithiadiaz-gly-psdap 4591: tolhs-ithiadiaz-bala-betathio3 4592: phhs-24thiaz-bala-betahdbph 4593: phhs-25methiaz-bala-betafu2 4594: bhs-nme35pyr-bala-betafphe 4595: ibhs-24thioph-gly-betapym 104596: toihs-25thiaz-gly-csdap 4597: ibhs-nme35pyr-gly-betafphe 4598: gua-24thiaz-gly-betabediox 4599: bim-25thioph-gly-betameph 4600: 2py-25oxaz-gly-zdap 154601: ibhs-ithiadiaz-gly-betabediox 4602: bhs-25oxaz-gly-betabediox 4603: ibhs-25methiaz-bala-betah35dc 4604: bhs-24thiazme-ala-betameph 4605: gua-24thiaz-gly-betaimid 204606: bhs-25thiaz-gly-betaipro 4607: ibhs-25methiaz-bala-betafu2 4608: bhs-24thioph-bala-psdapee 4609: phhs-24thiaz-gly-betah35dc 4610: bhs-52thiaz-ala-psdap 254611: ibhs-25oxaz-gly-betapyee 4612: ibhs-25thiaz-gly-psdap 4613: nmhs-25oxaz-bala-zdap 4614: tolhs-24thiaz-gly-betabdimo 4615: bhs-25thiaz-afa-beta23meoph 304616: gua-24thiaz-gly-betampy 4617: tolhs-ithiadiaz-gly-betatrif 4618: bhs-42pym-ala-betameph 4619: bhs-25methiaz-ala-betacthioph 4620: phhs-oxadiaz-bala-betadcphtb 354621: bhs-24thioph-bala-betafu3 4622: tolhs-25oxaz-bafa-betafu2 4623: bhs-25oxaz-bala-betaamibe WO 00!66618 PCTIEP00103469 4624: bim-25methiaz-gly-betadcph 4625: gua-24thiaz-gly-betacph 4626: bhs-24thiaz-nmgly-beta34meoph 4627: tolhs-me25thioph-bala-betaph 4628: bhs-nme35pyr-gly-betafluo 4629: ibhs-25thiaz-bala-betahmph 4630: phhs-25oxaz-bala-betaph 4631: tolhs-me24thioph-ala-beta34meoph 4632: bhs-nme35pyr-gly-beta35dbph 104633: dimethpym-24thiaz-gly-betadcph 4634: ibhs-25methiaz-bala-betaimid 4635: ibhs-24thioph-bala-betabthioph 4636: tolhs-nme35pyr-bala-betapyee 4637: hyd-25thiaz-gly-betainyl 154638: tolhs-25oxaz-bala-betapyr 4639: bhs-ithiadiaz-gly-betahdcph 4640: bhs-oxadiaz-bala-betadmoph 4641: phhs-me25oxaz-ala-betadcph 4642: phhs-25methiaz-bala-betameph 204643: bhs-24thiaz-gly-betahc 4644: bhs-me24thioph-leu-betapy 4645: ibhs-25methiaz-bala-betahc 4646: phhs-me24oxaz-ala-betaph 4647: phhs-24thiaz-gly-betahmofu 254648: bhs-ithiadiaz-ala-betadmoph 4649: dimethpym-25thioph-gly-betahdcph 4650: bim-25methiaz-bala-betadcph 4651: bhs-24thioph-nmgly-betadmoph 4652: tolhs-25methiaz-bala-betatbuph 304653: phhs-24thiaz-gly-betathiome 4654: phhs-25oxaz-gly-psdaptb 4655: ibhs-ithiadiaz-bala-betapbiph 4656: ibhs-nme35pyr-bala-betaet 4657: tolhs-25thiaz-bala-zdaptb 354658: bhs-25thiaz-gly-beta3quin 4659: bim-52thiaz-ala-betainyl 4660: bhs-24thioph-ala-betadito 4661: 2py-42nmeim-ala-psdap 4662: phhs-25thiaz-gly-beta3quin 4663: tolhs-oxadiaz-bala-beta13bendi 4664: ibhs-25methiaz-gly-betabmph 4665: ibhs-25methiaz-bala-beta23meoph 4666: bhs-24thioph-gly-betahb 4667: tolhs-oxadiaz-gly-betafluo 4668: gua-24thiaz-gly-betabph 4669: ibhs-25oxaz-gly-aspaba 104670: bhs-25oxaz-ala-zdap 4671: tolhs-25thiaz-bala-betahni 4672: bim-42nmeim-gly-betamesu 4673: dhthi-24thiaz-gly-betapy 4674: phhs-nme35pyr-bala-psdap 154675: ibhs-25oxaz-gly-betatos 4676: bhs-nme35pyr-gly-betapyee 4677: 2py-24thiaz-bala-psdap 4678: tolhs-oxadiaz-gly-betah35dc 4679: tolhs-24thioph-bala-betapytb 204680: gua-24thiaz-gly-beta34dcph 4681: phhs-24thioph-bala-zdap 4682: bhs-ithiadiaz-bala-betahni 4683: gua-25thiaz-gly-betampy 4684: phhs-nme35pyr-bala-beta34dcph 254685: tolhs-nme35pyr-bala-betahph 4686: bhs-24thioph-ala-betameph 4687: phhs-25thiaz-bala-betabediox 4688: ibhs-24thioph-gly-betahmph 4689: tolhs-nme35pyr-bala-betahmph 304690: bhs-25oxaz-gly-betampy 4691: bhs-ithiadiaz-bala-beta4bph 4692: phhs-25methiaz-gly-betadtrif 4693: bhs-me25thiaz-gly-zdap 4694: phhs-25oxaz-gly-busu2be 354695: bhs-nme35pyr-bala-betafu2 4696: ibhs-25methiaz-bala-betathiobe 4697: ibhs-25oxaz-gly-betabdimo 4698: bim-ithiadiaz-ala-psdap 4699: tolhs-oxadiaz-gly-betaimid 4700: ibhs-24thioph-gly-betaftrif 4701: 2py-me25thiaz-ala-betadcph 4702: ibhs-25methiaz-bala-suabu 4703: bhs-24thiaz-bala-betafu3 4704: ibhs-25thiaz-gly-beta13bendi 4705: bim-53pyrazo-gly-zdap 4706: bhs-nme35pyr-bala-betapych 4707:bhs-25methiaz-bala-betahdcph 4708: phhs-24thiaz-gly-betaphethio 4709: ibhs-25methiaz-gly-betahmofu 4710: bhs-25oxaz-bala-betahmofu 4711: phhs-25methiaz-gly-betafbph 4712:ibhs-24thiaz-gly-betamethi 4713: ibhs-25methiaz-gly-psdap 4714: phhs-nme35pyr-bala-betadmph 4715: phhs-oxadiaz-gly-betal3bendi 4716: tolhs-24thiaz-bala-betadcphee 4717:bhs-ithiadiaz-gly-betatos 4718: ibhs-25oxaz-gly-betaphethioa 4719: ibhs-nme35pyr-gly-beta4bph 4720: bhs-oxadiaz-nmgly-betahph 4721: tolhs-ithiadiaz-bala-betahcbph 4722:bhs-25thiaz-gly-betabdimo 4723: bhs-24thiaz-ala-ibsdap 4724: phhs-25methiaz-bala-betafph 4725: bhs-ithiadiaz-gly-betambiph 4726: gua-25methiaz-bala-betadcph 4727:bhs-nme35pyr-ala-betathioph 4728: ibhs-25thiaz-gly-betadcphtb 4729: bhs-nme35pyr-bala-betahni 4730: ibhs-24thiaz-bala-betaamibe 4731: bhs-me24thiaz-ala-zdap 4732:phhs-24thiaz-gly-betaph 4733: ibhs-25methiaz-gly-betahb 4734: bhs-24thiaz-gly-betatrif 4735; bhs-25oxaz-gly-aspbzla 4736: phhs-nme35pyr-gly-betadmoph 4737: bim-25oxaz-ala-zdap 4738: gua-24thiaz-gly-betaibph 4739: ibhs-nme35pyr-gly-betapyee 4740: dhim-25thiaz-gly-zdap 4741: tolhs-25methiaz-bala-beta3quin 4742: tolhs-me24thioph-bala-betadcph 4743: ibhs-oxadiaz-bala-betaomebendi 104744: tolhs-25thiaz-gly-betaheph 4745: bhs-53pyrazo-leu-betapy 4746: bim-25fur-bala-psdap 4747: bim-25thiaz-leu-psdap 4748: bim-42nmeim-bala-zdap 154749: gua-26py-gly-betabmph 4750: bim-me25thiaz-leu-beta34meoph 4751: bim-oxadiaz-bala-asppha 4752: bhs-24im-gly-betapy 4753: tolhs-25thiaz-bala-betadtrif 204754: phhs-25methiaz-bala-betapyr 4755: 2py-24th iaz-gly-betadito 4756: ibhs-24thioph-gly-betadmph 4757: phhs-oxadiaz-bala-psdaptb 4758: bhs-me24thioph-ala-betapy 254759: tolhs-me25thiaz-leu-psdap 4760: tolhs-24thiaz-bala-beta35dbph 4761: pahs-24thiaz-gly-betapy 4762: dhim-25thioph-ala-betapy 4763: bhs-24thioph-bala-betahmo 304764: bhs-me24oxaz-ala-betaph 4765: ibhs-25oxaz-gly-betatbuph 4766: thpym-26py-gly-betainyl 4767: bhs-25methiaz-bala-beta23meoph 4768: phhs-24thiaz-bala-betabpy 354769: 2py-53pyrazo-ala-zdap 4770: tolhs-25methiaz-bala-betabpy 4771: phhs-oxadiaz-bala-betahdcph WO 00!66618 PCTIEP00103469 4772; bhs-24thioph-gly-betamethioph 4773: phhs-ithiadiaz-gly-betahdbph 4774: phhs-25thiaz-gly-zdaptb 4775: bhs-ithiadiaz-gly-betabthioph 4776: bhs-24thioph-bala-beta34dcph 4777: bhs-24thiaz-gly-betahmofu 4778: bhs-25thiaz-bala-betadcphch 4779: tolhs-25methiaz-gly-betatbuph 4780: ibhs-24thiaz-bafa-aspaba 4781: thpym-25thiaz-gly-beta35dbph 4782: gua-26py-gly-betacph 4783: ibhs-oxadiaz-bala-betadcph 4784: ibhs-24thiaz-gly-betainyl 4785: bim-24py-gly-zdap 4786: 2py-52thiaz-ala-zdap 4787: phhs-24thiaz-gly-beta13bendi 4788: ibhs-ithiadiaz-bala-busu2be 4789: bhs-35thioph-ala-betadcph 4790: phhs-25oxaz-bala-beta34dcph 4791: bhs-24thiaz-gly-betabthioph 4792: phhs-24thiaz-bala-betaamibe 4793: bhs-24thioph-gly-betadcph 4794: tolhs-ithiadiaz-gly-betatbuph 4795: ibhs-nme35pyr-bala-betaol 4796: tolhs-25methiaz-gly-betacbph 4797: phhs-24thiaz-bala-betadmph 4798: tolhs-24thioph-bala-betaipro 4799: bhs-25thiaz-ala-betaipro 4800: bhs-25thiaz-bala-betaamibe 4801: tolhs-24thiaz-bala-betambiph 4802: bhs-triaz-gly-betapy 4803: bhs-25oxaz-gly-betathioph 4804: bhs-25oxaz-bala-betafu3 4805: ibhs-25oxaz-bala-zdapch 4806: bhs-35thioph-bala-betadcph 4807: phhs-oxadiaz-bala-betadcphch 4808: phhs-ithiadiaz-bala-asppha 4809: bim-me24thiaz-gly-beta34meoph 4810: ibhs-25methiaz-gly-betaftrif 4811: 3pmhs-25methiaz-bala-betapy 4812: ibhs-25thiaz-gly-betadhbfu 4813: tolhs-24thioph-gly-betaipr 4814: ibhs-25thiaz-gly-betabmph 4815: bhs-25methiaz-bala-zdaptb 4816: bhs-25thiaz-ala-betaheph 4817: bhs-ithiadiaz-bala-betahmph 104818: bim-42pym-gly-betadcph 4819: bhs-25methiaz-gly-psdap 4820: phhs-25oxaz-gly-betacph 4821: bhs-nme35pyr-gly-zdap 4822: bhs-oxadiaz-bala-beta34meoph 154823: tolhs-me24thiaz-leu-betapy 4824: ibhs-25oxaz-bala-betahc 4825; bhs-25methiaz-bala-betahmph 4826: ibhs-24thiaz-bala-zdapch 4827: tolhs-25methiaz-gly-betadmph 204828: 2py-26py-gly-betadcph 4829: dhim-24thiaz-ala-betadcph 4830: bhs-24thiaz-ala-betacph 4831: phhs-ithiadiaz-bala-aspibua 4832: bhs-25thiaz-ala-betahph 254833: phhs-24thioph-bala-betahdcph 4834: bhs-24thiaz-nmgly-betathioph 4835: tolhs-ithiadiaz-gly-asppha 4836: ibhs-24thioph-gly-betaphethioa 4837: phhs-24thiaz-bala-psdap 304838: phhs-25oxaz-bala-betathio3 4839: ibhs-24thioph-gly-betatbuph 4840: ibhs-nme35pyr-gly-betadcphee 4841: phhs-me24thiaz-bala-zdap 4842: ibhs-24thioph-bala-betahdbph 354843: tolhs-25thiaz-bala-betaipr 4844: gua-26py-gly-betabenfu 4845: ibhs-oxadiaz-bala-betadtrif W000166618 PCTlEP00103469 4846: dhim-24thiaz-gly-betahcbph 4847: dhim-25thiaz-ala-betadcph 4848: tolhs-24thioph-gly-betabnaphth 4849: bhs-24thiaz-bala-betahmo 4850: ibhs-oxadiaz-bala-betadbph 4851: phhs-25methiaz-bala-betahmo 4852: ibhs-25methiaz-gly-betapy 4853: tolhs-25methiaz-gly-zdapch 4854: phhs-25oxaz-bala-betahcbph 104855: tolhs-nme35pyr-bala-betaet 4856: tolhs-ithiadiaz-bala-betapytb 4857: nmhs-24thiaz-gly-betadcph 4858: phhs-25thiaz-gly-betaibph 4859: tolhs-24thiaz-bala-betabph 154860: tolhs-25oxaz-bala-betaanaphth 4861: bhs-24thioph-bala-betabthioph 4862: phhs-oxadiaz-gly-betadmoph 4863: bim-me25oxaz-ala-psdap 4864: ibhs-25methiaz-bala-betahdbph 204865: bhs-24thioph-ala-betacph 4866: ibhs-24thioph-bala-betadhbfu 4867: ibhs-nme35pyr-bala-betaipr 4868: bim-25oxaz-bala-zdap 4869: bim-42nmeim-leu-zdap 254870: ibhs-oxadiaz-gly-betahdbph 4871: phhs-me24oxaz-ala-beta34meoph 4872: bhs-oxadiaz-bala-betahmo 4873: phhs-24thiaz-bala-betadhbfu 4874: bhs-25fur-bala-zdap 304875: tolhs-me25thioph-gly-betapy 4876: ibhs-25thiaz-gly-betafph 4877: 2py-me24thiaz-bala-betapy 4878: phhs-ithiadiaz-bala-beta4bph 4879: phhs-me25thioph-gly-zdap 354880: ibhs-24thioph-bala-betapytb 4881: dhim-26py-gly-betadcph 4882: phhs-25methiaz-gly-betaoxope 4883: bhs-25thiaz-bala-betapy 4884: bim-25thiaz-gly-betapbiph 4885: phhs-25thiaz-bala-betahb 4886: bhs-ithiadiaz-gly-beta3quin 4887: ibhs-25thiaz-gly-betacthioph 4888: bhs-25methiaz-bala-ibsdap 4889: bim-42pym-ala-betainyl 4890: bhs-24thiaz-bala-betapym 4891: bim-25thiaz-bala-csdap 104892: bhs-25oxaz-gly-betamesu 4893: bhs-24thioph-ala-betahmph 4894: ibhs-25methiaz-bala-betahcbph 4895: tolhs-ithiadiaz-bala-psdapch 4896: tolhs-24thiaz-gly-betampy 154897: bhs-triaz-bala-psdap 4898: bhs-nme35pyr-gly-betabnaphth 4899: phhs-oxadiaz-bala-betabnaphth 4900: tolhs-25thiaz-bala-betamethioph 4901: tolhs-oxadiaz-gly-betadbph 204902: tolhs-nme35pyr-bala-betadhbfu 4903: bhs-24thiaz-ala-betaanaphth 4904: ibhs-25thiaz-gly-betadcphch 4905: bhs-oxadiaz-gly-betapbiph 4906: ibhs-ithiadiaz-gly-betampy 254907: tolhs-25thiaz-gly-aspaba 4908: bhs-nme35pyr-bala-betabdimo 4909: tolhs-oxadiaz-gly-betadcphtb 4910: tolhs-oxadiaz-bala-beta3quin 4911: bim-oxadiaz-bala-psdap 304912: phhs-25methiaz-bala-beta34meoph 4913: phhs-24thiaz-gly-betaftrif 4914: bhs-nme35pyr-gly-betacbph 4915: ibhs-oxadiaz-bala-suabu 4916: bhs-triaz-bala-betadcph 354917: 2py-24oxaz-leu-betapy 4918: dhim-42pym-ala-betainyl 4919: phhs-25oxaz-gly-betaftrif W000166618 PCTlEP00/03469 4920: tolhs-25thiaz-bala-betaanaphth 4921: bhs-thiadiaz-bala-psdap 4922: tolhs-24thioph-bala-betainyl 4923: tolhs-25oxaz-gly-betathioph 4924: bhs-42pym-ala-betapy 4925: 2py-26py-gly-beta23meoph 4926: phhs-ithiadiaz-gly-betahph 4927: phhs-25methiaz-gly-betapym 4928: ibhs-25methiaz-bala-betacthioph 104929: bhs-24thiaz-gly-betabenfu 4930: tolhs-25thiaz-bala-betaphethioa 4931: bhs-25thiaz-gly-ibsdap 4932: ibhs-25thiaz-bala-betainyl 4933: tolhs-24thioph-bala-psdaptb 154934: ibhs-24thiaz-bala-betadhbfu 4935: bhs-nme35pyr-bala-betaoxope 4936: tolhs-25methiaz-gly-beta13bendi 4937: ibhs-24thiaz-gly-beta34dcph 4938: bim-me24oxaz-ala-zdap 204939: phhs-nme35pyr-bala-betapbiph 4940: dhim-26py-ala-betadcph 4941: phhs-25methiaz-gly-betacthioph 4942: 2py-42nmeim-bala-zdap 4943: ibhs-25thiaz-gly-betahbcph 254944: ibhs-25thiaz-gly-betacph 4945: ibhs-25oxaz-gly-betacbph 4946: tolhs-25thiaz-bala-betadcph 4947: dhim-24oxaz-gly-betameph 4948: bhs-nme35pyr-gly-betatrif 304949: bhs-24thioph-bala-betahph 4950: bhs-nme35pyr-bala-aspibua 4951: bhs-25thiaz-gly-betamesu 4952: bim-me24oxaz-bala-betaph 4953: bhs-25oxaz-bala-betahb 354954: bim-ithiadiaz-ala-zdap 4955: phhs-oxadiaz-bala-betabmph 4956: bhs-oxadiaz-ala-betadito 4957:phhs-ithiadiaz-bala-betatbuph 4958:bhs-25oxaz-nmgly-betaipro 4959:2py-25fur-leu-psdap 4960:bhs-ithiadiaz-gly-asppha 4961:ibhs-25methiaz-gly-psdapch 4962:tolhs-25thiaz-gly-psdap 4963:bhs-oxadiaz-bala-betaet 4964:bhs-24thioph-bala-betamethioph 4965:bim-24thioph-gly-aspibua 4966:phhs-me25thioph-ala-betaph 4967:tolhs-nme35pyr-gly-ibsdap 4968:ibhs-24thioph-bala-beta23meoph 4969:tolhs-oxadiaz-bala-betadhbfu 4970:2py-25thiaz-gly-betadito 4971:phhs-ithiadiaz-gly-betahc 4972:phhs-24thioph-bala-betahbcph 4973:bhs-25methiaz-bala-betah35dc 4974:gua-25thioph-gly-betacph 4975:phhs-oxadiaz-gly-beta23meoph 4976:ibhs-24thioph-gly-betah35dc 4977:phhs-24thioph-gly-betaanaphth 4978:bim-24thiaz-bala-csdap 4979:2py-24thiaz-gly-betameph 4980:tolhs-24thioph-bala-betambiph 4981:2py-24im-leu-betadcph 4982:tolhs-nme35pyr-bala-betah35dc 4983:bhs-25oxaz-gly-ibsdap 4984:ibhs-25methiaz-gly-ibsdap 4985:tolhs-ithiadiaz-gly-betameph 4986:bhs-24thiaz-bala-betainyl 4987:bim-me25thiaz-bala-betadcph 4988:tolhs-25methiaz-bala-beta35dbph 4989:bhs-me25oxaz-gly-betaph 4990:phhs-25thiaz-gly-betadhbfu 4991:cima-42nmeim-bala-betapy 4992:phhs-24thiaz-bala-betabthioph 4993:bim-24thioph-leu-psdap W000166618 PCTlEP00103469 4994:tolhs-me25oxaz-bala-beta34meoph 4995:ibhs-oxadiaz-bala-betainyl 4996:ibhs-ithiadiaz-bala-betaipr 4997:tolhs-nme35pyr-bala-betatos 4998:3pmhs-25thioph-gly-betapy 4999:2py-25thiaz-gly-aspaba 5000:bim-25methiaz-leu-betapy 5001:bim-24thiaz-bala-betadcph 5002:bhs-24thioph-gly-ibsdap 5003:2py-53pyrazo-gly-psdap 5004:ibhs-24thioph-gly-betaamibe 5005:tolhs-me24thiaz-gly-betapy 5006:bhs-52thiaz-gly-betameph 5007:ibhs-ithiadiaz-bala-betathioph 5008:ibhs-25thiaz-gly-betadmph 5009:bim-24im-gly-zdap 5010:ibhs-24thioph-bala-psdaptb 5011:bim-24thioph-bala-aspibua 5012:bhs-ithiadiaz-nmgly-betahmph 5013:bhs-25thiaz-bala-betainyl 5014:phhs-25methiaz-gly-betacbph 5015:bim-25thiaz-gly-betainyl 5016:phhs-24thioph-gly-betabediox 5017:phhs-oxadiaz-gly-betabnaphth 5018:ibhs-nme35pyr-gly-betabediox 5019:phhs-25thiaz-bala-betah35dc 5020:tolhs-nme35pyr-bala-beta34meoph 5021:phhs-me24thiaz-gly-psdap 5022:phhs-24thioph-bala-betabdimo 5023:tolhs-nme35pyr-gly-betaipro 5024:ibhs-25thiaz-gly-betaomebendi 5025:phhs-25oxaz-gly-betabmph 5026:dhim-26py-ala-betainyl 5027:thpym-26py-gly-betacbph 5028:ibhs-24thiaz-bala-betapytb 5029;ibhs-25thiaz-bala-betaimid 5030:ibhs-ithiadiaz-gly-betaol 5031:ibhs-oxadiaz-bala-beta34dcph 5032:phhs-me25oxaz-gly-betaph 5033:tolhs-24thioph-bala-betafphe 5034:ibhs-24thioph-bala-betaftrif 5035:bim-42pym-ala-betapy 5036:bhs-nme35pyr-ala-betacph 5037:tolhs-nme35pyr-gly-betabenfu 5038:bim-42oxaz-ala-zdap 5039:ibhs-25oxaz-bala-betampy 5040:phhs-25thiaz-gly-betafphe 5041:dhim-26py-gly-beta34meoph 5042:ibhs-24thiaz-gly-betathiome 5043:bim-me24thioph-bala-betapy 5044:bim-24im-bala-zdap 5045:bhs-ithiadiaz-bala-betahbcph 5046:2py-25thiaz-gly-betadcph 5047:bim-me25oxaz-bala-betadcph 5048:phhs-25methiaz-bala-betathiobe 5049:ibhs-25oxaz-bala-beta3quin 5050:phhs-oxadiaz-bala-beta34meoph 5051:gua-42pym-gly-betabthioph 5052:bhs-35thioph-bala-betapy 5053:2py-42pym-gly-betainyl 5054:phhs-ithiadiaz-gly-beta4bph 5055:bhs-24thioph-bala-betahdcph 5056:ibhs-25methiaz-bala-betahni 5057:bim-25methiaz-leu-psdap 5058:tolhs-me25oxaz-ala-beta34meoph 5059:ibhs-25thiaz-bala-betampy 5060:phhs-25methiaz-gly-betaoxaz 5061:2pmhs-42pym-gly-betainyl 5062:tolhs-nme35pyr-gly-betapyr 5063:tolhs-25methiaz-bala-betapych 5064:tolhs-oxadiaz-gly-betadito 5065:tolhs-me25oxaz-ala-psdap 5066:bhs-ithiadiaz-bala-beta3quin 5067:2py-25oxaz-ala-psdap W000166618 PCTlEP00103469 5068:bim-24thioph-leu-betapy 5069:tolhs-25methiaz-bala-betahmo 5070:bhs-25methiaz-bala-zdapch 5071:bhs-24thiaz-bala-betamethi 5072:2pmhs-24thioph-bala-betamethioph 5073:bim-24thioph-gly-aspaba 5074:ibhs-25methihz-gly-betatrif 5075:bhs-24thioph-gly-beta3quin 5076:ibhs-oxadiaz-gly-betatrif 105077:2py-triaz-bala-betapy 5078:phhs-24thioph-bala-betameph 5079:bim-25oxaz-gly-psdap 5080:tolhs-nme35pyr-bala-betabthioph 5081:tolhs-25thiaz-gly-betahmph 155082:bhs-42nmeim-ala-betapy 5083:tolhs-25oxaz-bala-beta34meoph 5084:ibhs-24thiaz-gly-betameph 5085:bim-me24thioph-bala-betadcph 5086:2py-26py-gly-betabiph 205087:ibhs-25thiaz-bala-betaheph 5088:bhs-25thiaz-nmgly-betadhbfu 5089:tolhs-oxadiaz-gly-betameph 5090:bhs-nme35pyr-nmgly-beta34meoph 5091:dhpyrr-24thiaz-gly-betapy 255092:tolhs-25oxaz-bala-betathioph 5093:bhs-24thiaz-bala-betaipro 5094:bhs-25oxaz-ala-betamesu 5095:ibhs-24thioph-gly-betathiobe 5096:nmhs-25methiaz-gly-betadcph 305097:phhs-24thiaz-gly-aspibua 5098:bhs-oxadiaz-gly-betapytb 5099:bim-24thiaz-bala-psdap 5100:ibhs-nme35pyr-bala-betabenfu 5101:ibhs-24thiaz-bala-betaomebendi 355102:ibhs-25thiaz-bala-betabnaphth 5103:2py-25oxaz-leu-betapy 5104:phhs-ithiadiaz-gly-aspbzla 5105:ibhs-25thiaz-bala-betabdimo 5106:2py-me24thioph-gly-betadcph 5107:tolhs-oxadiaz-bala-betaipro 5108:ibhs-24thiaz-bala-betahmph 5109:bhs-25thiaz-gly-aspaba 5110:2py-35thioph-ala-betapy 5111:bhs-24thioph-gly-zdaptb 5112:phhs-nme35pyr-gly-betatrif 5113:tolhs-25oxaz-gly-betaphethioa 5114:thazep-24thiaz-gly-betadcph 5115:tolhs-ithiadiaz-gly-betadcphch 5116:phhs-25oxaz-bala-betafbph 5117:tolhs-25methiaz-gly-betamethioph 5118:impy-24thiaz-gly-betambiph 5119:phhs-oxadiaz-bala-betafu3 5120:tolhs-me24thiaz-leu-zdap 5121:ibhs-ithiadiaz-bala-betabediox 5122:bhs-oxadiaz-gly-betahc 5123:tolhs-24thiaz-gly-betahmph 5124:bhs-oxadiaz-bala-zdap 5125:bhs-oxadiaz-bala-betahbcph 5126:bim-24thiaz-gly-psdap 5127:bhs-24thiaz-ala-betampy 5128:2pmhs-25oxaz-gly-beta35dbph 5129:bhs-26py-gly-betainyl 5130:bhs-nme35pyr-bala-betapym 5131:2py-26py-met-zdap 5132:ibhs-25oxaz-bala-betacthioph 5133:impy-24thioph-gly-betabthioph 5134:tolhs-oxadiaz-gly-betahdcph 5135:bhs-24thiaz-gly-betapych 5136:bhs-oxadiaz-ala-psdap 5137:phhs-24thiaz-gly-betadcphee 5138:phhs-oxadiaz-gly-betaibph 5139:ibhs-25oxaz-bala-betadhbfu 5140:ibhs-25thiaz-bala-betathiobe 5141:bhs-nme35pyr-ala-betadcph W000166618 PCTlEP00103469 5142:bhs-25oxaz-bala-betampy 5143:2py-26py-ala-betainyl 5144:tolhs-25oxaz-bala-beta13bendi 5145:tolhs-nme35pyr-bala-betahmo 5146:bhs-nme35pyr-gly-betadbph 5147:bim-me25thioph-bala-psdap 5148:bhs-25oxaz-ala-beta34dcph 5149:ibhs-nme35pyr-gly-zdaptb 5150:tolhs-25methiaz-bala-betamethi 5151:bhs-nme35pyr-gly-beta13bendi 5152:2py-me25thioph-leu-psdap 5153:ibhs-24thioph-bala-betatbuph 5154:sabhs-24thiaz-gly-psdap 5155:bhs-25thiaz-bala-betahmph 5156:bim-triaz-gly-betapy 5157:phhs-24thioph-bala-betamethioph 5158:phhs-nme35pyr-bala-psdaptb 5159:dhim-24py-gly-betameph 5160:cima-25thiaz-bala-psdap 5161:bhs-24thiaz-gly-betampy 5162:tolhs-25methiaz-bala-beta23meoph 5163:2py-ithiadiaz-ala-betapy 5164:impy-25methiaz-gly-betabthioph 5165:ibhs-24thioph-bala-betaoxope 5166:tolhs-me25thiaz-gly-beta34meoph 5167:ibhs-nme35pyr-gly-betamethi 5168:ibhs-nme35pyr-gly-betabpy 5169:tolhs-25methiaz-bala-betaph 5170:tolhs-24thioph-gly-betapyr 5171:ibhs-25oxaz-bala-betahph 5172:bim-24thiaz-bala-betafphe 5173:tolhs-me24thioph-gly-betadcph 5174:bhs-ithiadiaz-gly-psdapch 5175:2py-24thiaz-bala-betapy 5176:tolhs-nme35pyr-bala-betaipro 5177:bhs-24thioph-nmgly-beta23meoph 5178:bim-52thiaz-gly-betadcph 5179: gua-24oxaz-gly-betathioph 5180: bhs-triaz-gly-betadcph 5181: bim-42nmeim-bala-betaipr 5182: tolhs-25thiaz-gly-betapym 5183: phhs-25thiaz-bala-betadcphch 5184: phhs-ithiadiaz-gly-betafu2 5185: phhs-ithiadiaz-bala-betampy 5186: phhs-ithiadiaz-gly-betadcphtb 5187: dhim-26py-ala-betapy 5188:phhs-oxadiaz-gly-betamesu 5189: ibhs-25methiaz-bala-psdapee 5190: phhs-me24thioph-gly-zdap 5191: ibhs-25oxaz-gly-betadmph 5192: bhs-25methiaz-gly-betadcphee 5193:bim-oxadiaz-ala-psdap 5194: phhs-ithiadiaz-gly-betaamibe 5195: 2py-rne25oxaz-gly-betaph 5196: phhs-25oxaz-bala-aspaba 5197: bim-me25oxaz-leu-zdap 5198:2py-25thiaz-bala-betafluo 5199: ibhs-24thioph-gly-betafphe 5200: bim-25thiaz-bala-betapy 5201: bhs-24thioph-bala-betatos 5202: gua-25thiaz-gly-betabdimo 5203:2py-42oxaz-ala-betadcph 5204: bhs-ithiadiaz-gly-betamethioph 5205: tolhs-me25thioph-leu-betapy 5206: bhs-25thiaz-ala-psdap 5207: ibhs-25thiaz-bala-betaoxope 5208:bhs-25oxaz-bala-betahmph 5209: bhs-25thiaz-gly-betabthioph 5210: tolhs-24thioph-gly-betabenfu 5211: phhs-me25thioph-leu-betaph 5212: tolhs-25thiaz-gly-ibsdap 5213:phhs-24thioph-gly-betahni 5214: bhs-24thioph-gfy-betaipr 5215: tolhs-me25oxaz-ala-betapy W000166618 ~ PCTIEP00103469 5216:phhs-me24thioph-bala-zdap 5217:bhs-25oxaz-bala-betathioph 5218:ibhs-ithiadiaz-gly-zdaptb 5219:ibhs-24thioph-bala-betahmo 5220:tolhs-25methiaz-gly-betabthioph 5221:tolhs-nme35pyr-gly-betaibph 5222:tolhs-me24thioph-gly-zdap 5223:phhs-24thiaz-gly-ibsdap 5224:tolhs-25thiaz-gly-betahbcph 5225:ibhs-oxadiaz-bala-betafph 5226:bhs-oxadiaz-nmgly-betahmph 5227:impy-42nmeim-bala-betameph 5228:gua-25thiaz-gly-betadcph 5229:phhs-oxadiaz-gly-betapym 5230:bhs-24thioph-gly-betabmph 5231:phhs-24thioph-gly-aspibua 5232:bhs-25oxaz-ala-betahph 5233:ibhs-24thiaz-gly-asppha 5234:2py-42oxaz-gly-zdap 5235:phhs-me24thiaz-gly-beta34meoph 5236:bhs-nme35pyr-bala-betamethi 5237:bhs-25oxaz-bala-betaheph 5238:dhim-25thiaz-ala-betameph 5239:bhs-ithiadiaz-gly-beta35dbph 5240:bim-oxadiaz-ala-betapy 5241:ibhs-nme35pyr-bala-betafu3 5242:phhs-ithiadiaz-gly-betabpy 5243:tolhs-ithiadiaz-gly-betah35dc 5244:2py-me25thiaz-ala-psdap 5245:bim-24im-ala-zdap 5246:bim-me25oxaz-gly-beta34meoph 5247:bhs-oxadiaz-bala-betapbiph 5248:bhs-24thioph-gly-beta4bph 5249:ibhs-25methiaz-bala-betaibph 5250:ibhs-24thiaz-gly-betatbuph 5251:bhs-oxadiaz-nmgly-betaanaphth 5252:phhs-25thiaz-gly-betamethi 5253:ibhs-ithiadiaz-gly-betadcphtb 5254:tolhs-24thioph-bala-betaet 5255:bhs-25methiaz-bala-beta34meoph 5256:ibhs-25thiaz-bala-suabu 5257:2py-42nmeim-gly-betapy 5258:tolhs-25thiaz-bala-betahmph 5259:bhs-25thiaz-gly-betahni 5260:2pmhs-42nmeim-bala-betaphethio 5261:tolhs-25methiaz-gly-betadbph 5262:ibhs-25thiaz-gly-betamethioph 5263:bhs-25thiaz-nmala-betameph 5264:2py-25methiaz-ala-betadcph 5265:bim-35fur-gly-betadcph 5266:bhs-oxadiaz-gly-betabenfu 5267:2py-oxadiaz-gly-betadcph 5268:bhs-25oxaz-bala-betaph 5269:phhs-24thioph-gly-betamethioph 5270:phhs-oxadiaz-bala-betafu2 5271:bhs-25methiaz-gly-betaoxaz 5272:tolhs-25thiaz-bala-betacbph 5273:tolhs-25oxaz-gly-betah35dc 5274:ibhs-24thiaz-gly-aspaba 5275:bim-25oxaz-bala-aspbzla 5276:tolhs-oxadiaz-bala-betahmofu 5277:bhs-25oxaz-bala-csdap 5278:tolhs-oxadiaz-gly-zdaptb 5279:phhs-25thiaz-bala-beta34dcph 5280:phhs-24thioph-bala-betambiph 5281:tolhs-24thiaz-gly-betabthioph 5282:bhs-24thiaz-bala-betaomebendi 5283:phhs-25thiaz-bala-beta35dbph 5284:ibhs-25methiaz-bala-aspbzla 5285:bhs-24thioph-ala-beta23meoph 5286:bhs-nme35pyr-bala-csdap 5287:phhs-24thiaz-bala-betafu3 5288:ibhs-25methiaz-gly-betaimid 5289:ibhs-24thiaz-gly-betafph W000166618 PCTlEP00103469 5290:impy-25oxaz-bala-betabenfu 5291;bhs-25thiaz-bala-suabu 5292:phhs-24thioph-gly-betabdimo 5293:tolhs-me24thioph-bala-psdap 5294:ibhs-24thioph-gly-betabenfu 5295:bim-35fur-ala-betapy 5296:bhs-25oxaz-bala-suabu 5297:bhs-25thiaz-bala-betamethi 5298:bhs-oxadiaz-bala-betabpy 5299:gua-24thiaz-gly-betaamibe 5300:bhs-25methiaz-bala-betathioph 5301:phhs-me25thiaz-gly-betadcph 5302:bhs-24thiaz-bala-ibsdap 5303:ibhs-25thiaz-bala-aspaba 5304:tolhs-ithiadiaz-bala-betaheph 5305:bhs-25oxaz-nmgly-betahph 5306:tolhs-24thioph-gly-betaol 5307:bhs-25methiaz-bala-betapych 5308:2py-42nmeim-bala-betaomebendi 5309:bhs-25methiaz-bala-betabthioph 5310:bhs-25thiaz-bala-betaimid 5311:tolhs-24thiaz-gly-betahb 5312:ibhs-ithiadiaz-bala-betacph 5313:ibhs-25oxaz-gly-asppha 5314:phhs-25thiaz-gly-betahdbph 5315;tolhs-ithiadiaz-g1y-betacthioph 5316:bhs-ithiadiaz-ala-beta13bendi 5317:tolhs-25oxaz-gly-betabph 5318:ibhs-25thiaz-bala-betaomebendi 5319:bhs-ithiadiaz-gly-ibsdap 5320:ibhs-24thiaz-gly-betapyee 5321:tolhs-24thioph-bala-betathiobe 5322:bhs-ithiadiaz-gly-betapyee 5323:ibhs-24thioph-gly-betadito 5324:bim-me24oxaz-leu-beta34meoph 5325:tolhs-24thiaz-bala-busu2be 5326:bhs-25thiaz-gly-betaoxaz 5327: ibhs-nme35pyr-gly-aspaba 5328: ibhs-nme35pyr-bala-betatrif 5329: bhs-25oxaz-bala-betafph 5330: tolhs-25oxaz-bala-betacbph 5331; 2py-oxadiaz-ala-betadcph 5332: phhs-24thiaz-bala-busu2be 5333: tolhs-25methiaz-gly-betainyl 5334: phhs-nme35pyr-bala-betafu3 5335: bhs-24thiaz-gly-betaphethioa 5336: ibhs-25oxaz-gly-aspibua 5337: tolhs-24thiaz-gly-betaphethioa 5338: 2py-25methiaz-gly-beta35dbph 5339: ibhs-nme35pyr-gly-betahb 5340: 2py-25thiaz-bala-betadcph 5341; 2py-me24thioph-leu-zdap 5342: phhs-nme35pyr-gly-betaipr 5343: bhs-25oxaz-nmgiy-betacph 5344: tolhs-oxadiaz-bala-beta4bph 5345: bhs-24thioph-ala-betadcph 5346. phhs-25thiaz-gly-beta13bendi 5347: tolhs-oxadiaz-gly-suabu 5348: bhs-25oxaz-bala-betapyee 5349: tolhs-25thiaz-bala-aspbzla 5350: tolhs-24thiaz-gly-betahcbph 5351: ibhs-oxadiaz-bala-betatrif 5352: bhs-24thiaz-bala-zdap 5353: ibhs-ithiadiaz-bala-betapyee 5354: 2py-42nmeim-leu-betadcph 5355: bim-42pym-gly-betameph 5356: tolhs-25oxaz-gly-betafph 5357: phhs-25oxaz-bala-betahmo 5358: bhs-25thioph-ala-betainyl 5359: phhs-25methiaz-gly-betaftrif 5360: bim-25oxaz-bala-betapy 5361: ibhs-nme35pyr-gly-betaol 5362: 2py-25methiaz-gly-betatbuph 5363: bhs-25thiaz-bala-betadmoph 5364: tolhs-24thioph-bala-csdap 5365: ibhs-oxadiaz-gly-beta13bendi 5366: tolhs-nme35pyr-gly-betampy 5367: bhs-25oxaz-bala-betaoxaz 5368: bhs-nme35pyr-nmgly-betafphe 5369: tolhs-nme35pyr-bala-betadcph 5370: tolhs-nme35pyr-bala-betadmoph 5371: 2py-25thiaz-gly-betapy 5372: dhim-42pym-ala-betameph 5373:bhs-24thiaz-bala-betapy 5374: phhs-oxadiaz-bala-betaimid 5375: ibhs-ithiadiaz-gly-betahmph 5376: tolhs-24thioph-bala-zdapch 5377: 2py-24oxaz-ala-psdap 5378:ibhs-ithiadiaz-gly-betambiph 5379: bim-nme35pyr-bala-psdap 5380: bim-25fur-leu-betadcph 5381: bhs-oxadiaz-bala-psdap 5382: phhs-25methiaz-bala-betaipr 5383:bhs-me25thiaz-ala-zdap 5384: ibhs-ithiadiaz-bala-betameph 5385: bhs-25oxaz-gly-beta13bendi 5386: tolhs-nme35pyr-bala-betabdimo 5387: ibhs-oxadiaz-bala-betahc 5388:bhs-25oxaz-bala-beta34dcph 5389: ibhs-25thiaz-bala-betadhbfu 5390: bhs-25methiaz-gly-betatrif 5391: ibhs-24thiaz-bala-betafu2 5392: phhs-ithiadiaz-gly-betabediox 5393:bhs-me25thioph-gly-betapy 5394: bhs-me25oxaz-ala-betadcph 5395: bhs-24thiaz-gly-betaphethio 5396: tolhs-24thiaz-bala-betadtrif 5397: bhs-ithiadiaz-nmgly-betaanaphth 5398:phhs-24thiaz-bala-betadcphtb 5399: bhs-ithiadiaz-ala-betacph 5400: thpym-24thioph-bala-psdap 5401:bhs-25oxaz-ala-betathioph 5402:bim-25methiaz-nmala-betadcph 5403:tolhs-25methiaz-gly-betahc 5404:bhs-25py-gly-betapy 5405:bim-me24thiaz-leu-zdap 5406:ibhs-oxadiaz-bala-betapyee 5407:phhs-me25oxaz-bala-betaph 5408:phhs-ithiadiaz-bala-betahmofu 5409:ibhs-25oxaz-bala-betafbph 105410:phhs-ithiadiaz-gly-betabmph 5411:phhs-25thiaz-gly-betabthioph 5412:ibhs-25methiaz-gly-aspibua 5413:tolhs-25thiaz-gly-psdapee 5414:bim-25thioph-ala-psdap 155415:bhs-ithiadiaz-nmgly-beta23meoph 5416:bhs-24thiaz-gly-betahb 5417:tolhs-25thiaz-gly-betamethi 5418:tolhs-oxadiaz-bala-betapych 5419:bim-25methiaz-ala-psdap 205420:bhs-me24oxaz-leu-betapy 5421:tolhs-25methiaz-gly-beta4bph 5422:dhim-26py-gly-betapy 5423:ibhs-oxadiaz-gly-asppha 5424:2py-24thiaz-leu-betadcph 255425:tolhs-oxadiaz-bala-betabmph 5426:bhs-oxadiaz-bala-betafu2 5427:bhs-25methiaz-bala-betaipro 5428:tolhs-25methiaz-gly-betapych 5429:phhs-25thiaz-bala-beta4bph 305430:bim-thiadiaz-leu-betadcph 5431:tolhs-24thiaz-gly-betabmph 5432:gua-42pym-gly-betaheph 5433:phhs-ithiadiaz-bala-betaipr 5434:2pmhs-25thiaz-bala-betapyr 355435:tolhs-me24thioph-leu-betadcph 543fi:bhs-oxadiaz-gly-betamethi 5437:phhs-24thiaz-bala-betathiome 5438:ibhs-nme35pyr-bala-betamethioph 5439:tolhs-me24thiaz-ala-psdap 5440:tolhs-24thioph-gly-betadito 5441:bhs-24thiaz-bala-betahdcph 5442:phhs-24thiaz-gly-betathiobe 5443:bim-42pym-ala-betameph 5444:phhs-24thiaz-gly-zdaptb 5445:bhs-24thiaz-gly-csdap 5446:bhs-oxadiaz-bala-betadtrif 5447:2py-42oxaz-a(a-psdap 5448:phhs-oxadiaz-bala-beta4bph 5449:bhs-oxadiaz-gly-betahdbph 5450:gua-26py-gly-beta4bph 5451:bhs-26pyrazi-ala-betapy 5452:tolhs-24thiaz-gly-psdaptb 5453:bhs-42nmeim-gly-betaheph 5454:ibhs-ithiadiaz-bala-betatbuph 5455:ibhs-24thioph-bala-betatrif 5456:phhs-25methiaz-gly-betaph 5457:bim-me24thioph-bala-zdap 5458:ibhs-oxadiaz-bala-betabthioph 5459:bhs-me24oxaz-leu-psdap 5460:tolhs-24thiaz-gly-betapych 5461:phhs-25thiaz-gly-betaol 5462:bhs-me24im-gly-zdap 5463:bim-25oxaz-gly-betathiome 5464:impy-25oxaz-bala-betaamibe 5465:tolhs-25methiaz-bala-asppha 5466:ibhs-24thioph-bala-betahdcph 5467:ibhs-25methiaz-bala-busu2be 5468:bhs-24thiaz-bala-betabmph 5469:bhs-me25thioph-gly-psdap 5470:ibhs-24thiaz-bala-betafluo 5471:dhim-24thiaz-ala-betapy 5472:bim-25thioph-leu-betadcph 5473:thpym-24thiaz-bala-psdap 5474:bhs-25oxaz-bala-betameph 5475: bhs-24thiaz-gly-betaoxaz 5476: bim-24thiaz-ala-psdap 5477: phhs-24thiaz-bala-betaoxaz 5478: bhs-ithiadiaz-bala-betahb 5479:bhs-ithiadiaz-bala-zdapee 5480; bhs-25oxaz-nmgly-betaoxaz 5481: bhs-25thiaz-nmgly-betadito 5482: bhs-nme35pyr-gly-psdapch 5483: ibhs-nme35pyr-gly-betadbph 5484:phhs-me24oxaz-leu-zdap 5485: bhs-oxadiaz-bala-betaoxaz 5486: bhs-oxadiaz-gly-betadito 5487: gua-42pym-gly-betathiobe 5488: bim-42nmeim-ala-betadcph 5489:bhs-42nmeim-gly-betabnaphth 5490: phhs-ithiadiaz-bala-betapytb 5491: 2py-ithiadiaz-bala-aspbzla 5492: bhs-24thioph-gly-betafbph 5493: bhs-oxadiaz-bala-betaanaphth 5494:bhs-me24oxaz-bala-betaph 5495: phhs-25thiaz-bala-betacthioph 5496: tolhs-25methiaz-bala-betapyee 5497: bhs-25methiaz-gly-beta35dbph 5498: phhs-me24oxaz-gly-betapy 5499:ibhs-25methiaz-bala-betaph 5500: 2py-24oxaz-bala-betapy 5501: ibhs-ithiadiaz-gly-aspibua 5502: phhs-25thiaz-gly-betadcphee 5503: bhs-24pym-gly-zdap 5504:tolhs-24thiaz-gly-betathioph 5505: tolhs-ithiadiaz-bala-betadcphch 5506: 2py-ithiadiaz-leu-betadcph 5507: phhs-24thiaz-bala-betapyee 5508: phhs-ithiadiaz-bala-betadcph 5509:bhs-25oxaz-bafa-betamethioph 5510: 2py-53pyrazo-leu-betapy 5511: ibhs-25oxaz-gly-betadcph 5512:ibhs-oxadiaz-gly-csdap 5513:bim-25methiaz-ala-betadcph 5514:phhs-25methiaz-bala-betamethioph 5515:bhs-oxadiaz-bala-psdaptb 5516:2py-me25thiaz-gly-betapy 5517:tolhs-25thiaz-gly-betacph 5518:impy-42nmeim-gly-betapyr 5519:bim-25methiaz-bala-betafphe 5520:phhs-25oxaz-gly-betapytb 5521:ibhs-25oxaz-gly-betapbiph 5522:2py-me25oxaz-bala-psdap 5523:bhs-ithiadiaz-bala-zdaptb 5524:2py-25methiaz-bafa-betafluo 5525:bhs-25thiaz-gly-betacthioph 5526:bhs-nme35pyr-bala-beta35dbph 5527:bhs-25oxaz-bala-betadcph 5528:tolhs-25thiaz-gly-betahdbph 5529:phhs-25thiaz-bala-betafph 5530:bhs-25thiaz-bala-betahdcph 5531:bhs-ithiadiaz-gly-betafu3 5532:bhs-25thiaz-bala-betapym 5533:bhs-ithiadiaz-ala-beta23meoph 5534:ibhs-nme35pyr-bala-betapych 5535:bhs-me25oxaz-bala-betapy 5536:2py-nme35pyr-bala-asppha 5537:2py-35thioph-bala-betapy 5538:phhs-nme35pyr-bala-betadcphee 5539:tolhs-25oxaz-bala-betabpy 5540:bhs-24thioph-bala-betacthioph 5541:bhs-24thioph-ala-betabpy 5542:bim-24im-leu-betadcph 5543:bhs-oxadiaz-gly-betamesu 5544:bhs-thiadiaz-gly-betadcph 5545:tolhs-25thiaz-bala-betameph 5546:bhs-thiadiaz-ala-psdap 5547:bhs-24thioph-bala-betadcphch 5548:bhs-ithiadiaz-gly-betabenfu 5549:ibhs-nme35pyr-bala-betadcphee 5550:bhs-me25oxaz-leu-betaph 5551:bhs-me24thiaz-leu-betadcph 5552:tolhs-25thiaz-gly-betatbuph 5553:gua-25thioph-gly-betacbph 5554:phhs-25methiaz-gly-betahph 5555:2py-me25thiaz-bala-psdap 5556:bhs-25methiaz-nmgly-betabpy 5557:bhs-oxadiaz-nmgly-betameph 5558:tolhs-24thiaz-gly-betacthioph 5559:dimethpyin-24thioph-gly-betameph 5560:ibhs-25oxaz-bala-betameph 5561:bhs-24thioph-bala-aspbzla 5562:ibhs-24thioph-bala-betabediox 5563:tolhs-25oxaz-bala-betaphethioa 5564:ibhs-24thiaz-gly-betabpy 5565:tolhs-25oxaz-bala-betacthioph 5566:tolhs-24thioph-bala-betapbiph 5567:ibhs-oxadiaz-bala-betahbcph 5568:phhs-oxadiaz-bala-betatrif 5569:bhs-25oxaz-bala-betabmph 5570:ibhs-oxadiaz-gly-betameph 5571:phhs-ithiadiaz-bala-betathiome 5572:tolhs-ithiadiaz-bala-betacthioph 5573:phhs-24thiaz-bala-betaftrif 5574:ibhs-ithiadiaz-bala-betamethi 5575:ibhs-ithiadiaz-gly-betabenfu 5576:ibhs-24thioph-gly-betahdcph 5577:phhs-me25thioph-bala-betaph 5578:2py-oxadiaz-gly-aspbzla 5579:bhs-24thiaz-nmgly-betameph 5580:tolhs-oxadiaz-bala-betadtrif 5581:bhs-oxadiaz-bala-beta3quin 5582:hs-25thioph-gly-betapy 5583:2py-53pyrazo-gly-betapy 5584:bhs-me25thiaz-leu-beta34meoph 5585:bgua-25thiaz-gly-betapy W000166618 PCTlEP00103469 5586:tolhs-nme35pyr-gly-betahni 5587:tolhs-25thiaz-gly-betafphe 5588:bhs-ithiadiaz-bala-csdap 5589:dhim-24thiaz-gly-betadtrif 5590:bim-24thiaz-bala-aspaba 5591:phhs-25thiaz-bala-betaheph 5592:bhs-24thiaz-gly-beta13bendi 5593:ibhs-25oxaz-bala-betathioph 5594:phhs-25methiaz-gly-betafu3 5595:tolhs-ithiadiaz-gly-betamethioph 5596:2py-42nmeim-gly-betatos 5597:ibhs-25oxaz-bala-betapyr 5598:ibhs-nme35pyr-bala-betamethi 5599:bhs-24thioph-bala-betaheph 5600:ibhs-24thiaz-bala-betadcphtb 5601:phhs-25thiaz-gly-betaheph 5602:ibhs-nme35pyr-bala-betaphethio 5603:ibhs-25methiaz-gly-betathio3 5604:tolhs-nme35pyr-gly-betaol 5605:tolhs-24thioph-gly-suabu 5606:bhs-25oxaz-gly-beta35dbph 5607:tolhs-24thiaz-giy-aspbzla 5608:bhs-24thioph-nmgly-betameph 5609:tolhs-ithiadiaz-bala-betahni 5610:bhs-25oxaz-gly-busu2be 5611:phhs-me25thioph-gly-beta34meoph 5612:bhs-24thiaz-gly-betadcphtb 5613:bim-26py-gly-betapy 5614:2py-me24thiaz-ala-betaph 5615:2py-me24oxaz-bala-betadcph 5616:bhs-25methiaz-gly-betahni 5617:bhs-25methiaz-gly-betabph 5618:bhs-24thiaz-bala-betafphe 5619:tolhs-ithiadiaz-bala-betafbph 5620:ibhs-oxadiaz-gly-betahc 5621:phhs-nme35pyr-baia-betabmph 5622:bhs-25methiaz-bala-betaimid 5623: tolhs-oxadiaz-bala-betadbph 5624: bhs-25methiaz-gly-beta34dcph 5625: bhs-ithiadiaz-nmgly-betainyl 5626: bhs-25methiaz-gly-zdap 5627: gua-25thioph-gly-beta13bendi 5628: phhs-24thiaz-bala-betaibph 5629: bhs-24thioph-bala-betamethi 5630: bim-me24oxaz-ala-betapy 5631: phhs-24thioph-bala-betahmo 5632:ibhs-24thioph-gly-betahmo 5633: tolhs-oxadiaz-bala-betafph 5634: ibhs-25oxaz-gly-betafluo 5635: phhs-25thiaz-gly-betaipro 5636: 2py-thiadiaz-ala-zdap 5637:tolhs-ithiadiaz-gly-betadcphtb 5638: ibhs-25thiaz-bala-betahb 5639: phhs-me24thioph-gly-betaph 5640: phhs-oxadiaz-gly-betapy 5641: tolhs-nme35pyr-gly-betathio3 5642:bhs-25methiaz-gly-betafphe 5643: bhs-nme35pyr-bala-betatrif 5644: phhs-nme35pyr-bala-betaheph 5645: bim-25thiaz-bala-asppha 5646: 2py-25thiaz-bala-beta34dcph 5647:bhs-24thiaz-gly-suabu 5648: ibhs-24thioph-bala-betafbph 5649: tolhs-25thiaz-bala-zdapee 5650: tolhs-ithiadiaz-bala-ibsdap 5651: bhs-25methiaz-gly-betaphethio 5652:ibhs-25oxaz-gly-betapym 5653: phhs-25oxaz-bala-betahb 5654: ibhs-ithiadiaz-gly-betainyl 5655: tolhs-me24thiaz-leu-psdap 5656; ibhs-25oxaz-bala-betathio3 5657:2py-53pyrazo-leu-psdap 5658: tolhs-nme35pyr-bala-betacph 5659: ibhs-25thiaz-bala-betafu2 WOOOIfi6618 PCTIEP00103469 5660: ibhs-25methiaz-gly-betadcphch 5661: bhs-me24oxaz-ala-zdap 5662: phhs-24thiaz-bala-beta34meoph 5663: tolhs-nme35pyr-bala-betathiobe 5664: phhs-me24thioph-gly-psdap 5665: tolhs-25oxaz-gly-betabpy 5666: 2py-25oxaz-gly-asppha 5667: ibhs-25methiaz-gly-betacbph 5668: bhs-25methiaz-bala-beta3quin 5669:tolhs-24thioph-gly-beta23meoph 5670: tolhs-nme35pyr-gly-betahcbph 5671: ibhs-25thiaz-bala-betaphethioa 5672: phhs-nme35pyr-gly-betafphe 5673: bhs-ithiadiaz-gly-betabediox 5674:ibhs-24thiaz-gly-betahdbph 5675: tolhs-25methiaz-bala-betathioph 5676: tolhs-nme35pyr-bala-betamethi 5677: tolhs-25thiaz-gly-betabenfu 5678: gua-24thiaz-gly-betabdimo 5679:phhs-24thiaz-bala-psdapee 5680: phhs-oxadiaz-gly-psdapch 5681: phhs-25oxaz-gly-betahdcph 5682: ibhs-24thioph-bala-betapym 5683: tolhs-25thiaz-gly-betahb 5684:bhs-42nmeim-gly-betaet 5685: bim-me25thioph-ala-betapy 5686: bim-25thiaz-leu-betadcph 5687: bhs-25thiaz-bala-betapyee 5688: ibhs-25methiaz-bala-betahmo 5689:phhs-25oxaz-gly-betacbph 5690: dhim-42pym-ala-zdap 5691: bhs-oxadiaz-gly-betathioph 5692: tolhs-25oxaz-gly-betahmo 5693: phhs-24thiaz-gly-betaipr 5694:tolhs-me24oxaz-leu-betapy 5695: phhs-oxadiaz-gly-betapytb 5696: ibhs-25methiaz-gly-beta35dbph W000166618 PCTlEP00103469 5697:bhs-ithiadiaz-gly-betadhbfu 5698:phhs-25thiaz-gly-busu2be 5699:bhs-nme35pyr-bala-betambiph 5700:bim-24thioph-gly-betapy 5701:ibhs-nme35pyr-gly-betadcphtb 5702:bim-25methiaz-gly-psdap 5703:phhs-nme35pyr-bala-betaipr 5704:gua-25thiaz-gly-betainyl 5705:bhs-25oxaz-bala-betafluo 105706:gua-25thioph-gly-betahmph 5707:tolhs-24thioph-gly-betainyl 5708:bhs-24thioph-bala-betaet 5709:tolhs-25oxaz-bala-betafu3 5710:2py-24thiaz-bala-beta34dcph 155711:gua-42pym-gly-betaph 5712:tolhs-ithiadiaz-gly-betahni 5713:2py-42nmeim-leu-psdap 5714:2py-24thiaz-hphe-psdap 5715:phhs-nme35pyr-gly-zdapee 205716:bhs-26py-ala-betapy 5717:ibhs-25methiaz-gly-betabph 5718:bhs-25methiaz-bala-betaphethioa 5719:tolhs-me25thiaz-aia-zdap 5720:bhs-24thioph-bala-beta3quin 255721:dhim-25thioph-ala-betainyl 5722:phhs-oxadiaz-gly-betahph 5723:tolhs-25oxaz-gly-betatbuph 5724:bhs-oxadiaz-gly-betaphethio 5725:bim-me24oxaz-ala-betaph 305726:tolhs-me25thiaz-leu-beta34meoph 5727:bim-24im-bala-betapy 5728:phhs-ithiadiaz-bala-betahb 5729:tolhs-25methiaz-gly-beta35dbph 5730:ibhs-25thiaz-bala-betadcphee 355731:ibhs-oxadiaz-bala-beta23meoph 5732:gua-24oxaz-gly-betatrif 5733:2py-25thioph-ala-zdap WOOOI6661 g PCTIEPOOI03469 5734: bhs-42oxaz-leu-betadcph 5735: bhs-triaz-bala-betapy 5736: phhs-25methiaz-bala-beta34dcph 5737: tolhs-ithiadiaz-gly-betabediox 5738: phhs-oxadiaz-bala-beta13bendi 5739: ibhs-25thiaz-bala-betahmo 5740: tolhs-25methiaz-bala-betadhbfu 5741: 2py-me24oxaz-leu-betapy 5742: phhs-ithiadiaz-bala-betafluo 105743: tolhs-24thioph-bala-betathiome 5744: bhs-52thiaz-gly-psdap 5745: tolhs-oxadiaz-gly-betabediox 5746: bhs-ithiadiaz-ala-betabnaphth 5747: phhs-oxadiaz-bala-betaamibe 155748: ibhs-oxadiaz-bala-betadcphch 5749: phhs-24thioph-bala-betafu2 5750: bhs-itbiadiaz-bala-betaoxope 5751: phhs-25oxaz-gly-betaoxaz 5752: ibhs-oxadiaz-bala-betaphethio 205753: bhs-25methiaz-nmgly-beta34meoph 5754: bhs-nme35pyr-gly-betadcph 5755: 2py-24oxaz-gly-betapy 5756: tolhs-25thiaz-bala-psdapch 5757: bhs-25thiaz-bala-betaoxaz 255758: bhs-24oxaz-gly-betameph 5759: bhs-24thioph-ala-betathioph 5760: ibhs-25oxaz-bala-betaipro 5761: phhs-ithiadiaz-bala-betambiph 5762: phhs-24thioph-bala-betaibph 305763: ibhs-ithiadiaz-bala-betadito 5764: tolhs-ithiadiaz-bala-betadcphee 5765: tolhs-oxadiaz-gly-aspbzla 5766: phhs-nme35pyr-gly-betaoxaz 57F7: bhs-42nmeim-gly-beta34dcph 355768: ibhs-oxadiaz-gly-betadito 5769: bhs-nme35pyr-gly-betahbcph 5770: tolhs-24thioph-bala-betamethioph W000166618 PCTlEP00J03469 5771:bhs-25methiaz-gly-beta23meoph 5772:bhs-25methiaz-ala-betahmph 5773:ibhs-25methiaz-bala-betadcphtb 5774:tolhs-24thioph-gly-betadbph 5775:tolhs-ithiadiaz-bala-betaet 5776:ibhs-ithiadiaz-gly-beta3quin 5777:2pm hs-42n meim-met-betapy 5778:ibhs-24thioph-gly-betafph 5779:ibhs-ithiadiaz-gly-betadbph 5780:phhs-25thiaz-bala-beta34meoph 5781:phhs-25oxaz-bala-betamesu 5782:bim-24thiaz-bala-betampy 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5815:phhs-ithiadiaz-gly-betaoxaz 5816:bhs-nme35pyr-bala-asppha 5817:tolhs-24thioph-gly-betahb 5818:bim-me25thioph-ala-psdap 5819:gua-24oxaz-gly-zdap 5820:phhs-25thiaz-gly-betabdimo 5821:phhs-25thiaz-gly-aspaba 5822:bhs-53pyrazo-bala-psdap 5823:2py-42nmeim-leu-zdap 5824:phhs-oxadiaz-gly-betadcphee 5825:imhs-25thiaz-gly-zdap 5826:phhs-25thiaz-bala-aspaba 5827:phhs-25methiaz-gly-betadhbfu 5828:bhs-24thiaz-bala-beta34meoph 5829:bhs-24thiaz-gly-betahmph 5830:2py-me25oxaz-bala-betaph 5831:hyd-42nmeim-bala-betadcph 5832:bhs-25thiaz-bala-beta3quin 5833:ibhs-ithiadiaz-bala-betabph 5834:ibhs-24thiaz-gly-betapbiph 5835:2py-25methiaz-bala-betadcph 5836:2py-25oxaz-leu-psdap 5837:tolhs-oxadiaz-gly-psdapch 5838:bhs-24thioph-ala-zdap 5839:bhs-24thioph-bala-betapych 5840:phhs-25thiaz-bala-betadcph 5841:bgua-42pym-gly-betapy 5842:bhs-25methiaz-nmgly-betacph 5843:impy-25oxaz-bala-betafbph 5844:phhs-24thiaz-gly-betadcphch 5845:phhs-25methiaz-bala-betaimid 5846:ibhs-25methiaz-bala-betahmofu 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5970:bhs-nme35pyr-nmgly-betacthioph 5971:bhs-35fur-bala-psdap 5972:bhs-24thiaz-bala-betaftrif 5973:bhs-25oxaz-gly-betafbph 5974:tolhs-25thiaz-gly-betaibph 5975:2py-me24thiaz-gly-betadcph 5976:2py-me24oxaz-bala-psdap 5977:bim-ithiadiaz-ala-betadcph 5978:2py-25thiaz-gly-betaol 5979:phhs-25oxaz-bala-zdapee 5980:tolhs-25thiaz-bala-beta23meoph 5981:bhs-25thiaz-gly-betahbcph 5982:ibhs-oxadiaz-gly-betahmofu 5983:ibhs-ithiadiaz-gly-betahbcph 5984:2py-25thiaz-bala-betahni 5985:tolhs-24thiaz-bala-betaipr 5986:2py-25thioph-ala-betapy 5987:ibhs-oxadiaz-gly-betabthioph 5988:ibhs-25methiaz-gly-betapym 5989:2py-24thiaz-bala-betadcph 5990:phhs-me25thioph-leu-betadcph 5991:ibhs-24thioph-gly-betainyl 5992:phhs-24thiaz-bala-betatbuph 5993: tolhs-oxadiaz-bala-psdaptb 5994: dhim-24oxaz-ala-betapy 5995: ibhs-25methiaz-bala-betafluo 5996: gua-26py-gly-betahph 5997:phhs-25thiaz-bala-psdapee 5998: phhs-24thiaz-gly-betaol 5999: bhs-25methiaz-bala-betaol 6000: 2py-nme35pyr-gly-aspibua 6001: ibhs-25oxaz-gly-beta35dbph 6002:tolhs-nme35pyr-gly-betahb 6003: ibhs-nme35pyr-gly-betaheph 6004: bhs-25oxaz-nmgly-betamesu 6005: 2py-24oxaz-ala-betadcph 6006: ibhs-ithiadiaz-gly-betaamibe 6007:tolhs-24thioph-gly-betadcphee 6008: tolhs-25thiaz-bala-asppha 6009: bhs-24thioph-bala-betadhbfu 6010: ibhs-ithiadiaz-bala-betadbph 6011: phhs-oxadiaz-gly-betathio3 6012:bhs-nme35pyr-nmgly-ibsdap 6013: ibhs-24thiaz-gly-betamethioph 6014: ibhs-oxadiaz-bala-betathio3 6015: 2py-25oxaz-nmgly-betadcph 6016: 2py-42n meim-gly-betahcbph 6017:toihs-24thioph-gly-betahdbph 6018: ibhs-nme35pyr-gly-betahdbph 6019: ibhs-24thiaz-gly-betabthioph 6020: bhs-25oxaz-bala-betapym 6021: ibhs-25methiaz-bala-betadito 6022:bhs-25thiaz-gly-betapbiph 6023: bhs-ithiadiaz-gly-betaibph 6024: ibhs-24thiaz-gly-betahni 6025: phhs-25oxaz-bala-betameph 6026: 2py-ith iadiaz-gly-aspbzla 6027:bhs-25methiaz-gly-betathiome 6028: phhs-ithiadiaz-gly-betahdcph 6029: tolhs-nme35pyr-bala-betaheph 6030:tolhs-25thiaz-bala-betabph 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6062:tolhs-me25thioph-leu-psdap 6063:thazep-42pym-gly-betapy 6064:ibhs-oxadiaz-bala-beta13bendi 6065:tolhs-25thiaz-gly-betafu3 6066:ibhs-oxadiaz-gly-betacbph 6067:gua-25thiaz-gly-betabpy 6068:phhs-nme35pyr-bala-csdap 6069:bim-53py~azo-gly-psdap 6070:ibhs-ithiadiaz-bala-betaimid 6071:bhs-52thiaz-ala-zdap 6072:ibhs-24thiaz-bala-betaheph 6073:tolhs-25oxaz-gly-betatos 6074:2py-24oxaz-bala-betadcph 6075:bhs-35thioph-leu-zdap 6076:bhs-ithiadiaz-bala-zdapch 6077:bhs-24thioph-nmgly-betaanaphth 6078:tolhs-25methiaz-gly-psdap 6079.bhs-me24oxaz-ala-betapy 6080:ibhs-25methiaz-gly-betadhbfu 6081:bhs-25thiaz-bala-ibsdap 6082:tolhs-nme35pyr-gly-betahdbph 6083:2py-42nmeim-bala-betaibph 6084:phhs-24thiaz-gly-betadbph 6085:phhs-25oxaz-bala-betafphe 6086:2py-26py-gly-zdap 6087:tolhs-oxadiaz-gly-betabthioph 6088:tolhs-25oxaz-bala-betadtrif 6089:bim-me25oxaz-leu-betaph 6090:ibhs-ithiadiaz-bala-beta34meoph 6091:phhs-nme35pyr-gly-zdaptb 6092:ibhs-24thiaz-bala-aspibua 6093:tolhs-24thioph-gly-betabpy 6094:bhs-ithiadiaz-gly-betadmoph 6095:gua-24thiaz-gly-betaphethio 6096:phhs-oxadiaz-bala-betadtrif 6097:ibhs-24thioph-bala-asppha 6098:phhs-nme35pyr-gly-betacthioph 6099:tolhs-25methiaz-bala-betaanaphth 6100:bhs-ithiadiaz-gly-betadcphch 6101:bhs-25methiaz-bala-betahni 6102:bhs-24thiaz-gly-psdapch 6103:bim-42nmeim-leu-betadcph W000166618 PCTIEPOOl03469 6104:tolhs-24thioph-bala-beta34meoph 6105:tolhs-24thiaz-bala-betafph 6106:tolhs-oxadiaz-gly-betaph 6107:phhs-ithiadiaz-gly-aspaba 6108:phhs-25oxaz-bala-ibsdap 6109.ibhs-25thiaz-gly-betabpy 6110:bhs-25methiaz-bala-betabnaphth 6111;tolhs-25oxaz-bala-betambiph 6112:tolhs-me25thioph-gly-beta34meoph 106113:tolhs-25oxaz-bala-betathiome 6114:dhim-25thioph-gly-betainyl 6115:ibhs-25oxaz-bala-aspibua 6116:phhs-oxadiaz-gly-suabu 6117:ibhs-nme35pyr-bala-beta35dbph 156118:2py-25methiaz-leu-psdap 6119:bim-thiadiaz-gly-psdap 6120:ibhs-ithiadiaz-gly-betadcphch 6121:tolhs-oxadiaz-bala-betaibph 6122:bhs-ithiadiaz-bala-betafph 206123:ibhs-oxadiaz-bala-betahdbph 6124:bhs-25thiaz-bala-betafph 6125:phhs-nme35pyr-gly-betapym 6126:ibhs-25oxaz-bala-betadcph 6127:phhs-25oxaz-bala-betahdbph 256128:tolhs-oxadiaz-bala-betadmoph 6129:tolhs-24thioph-gly-betahdcph 6130:bhs-25methiaz-bala-betaph 6131:bhs-25thiaz-gly-betapyee 6132:tolhs-25methiaz-bala-betaimid 306133:gua-42pym-gly-betathio3 6134:bhs-25methiaz-nmgly-beta23meoph 6135:sabhs-42nmeim-gly-betapy 6136:bhs-24thiaz-bala-betathioph 6137:impy-25methiaz-bala-betaphethioa 356138:bhs-nme35pyr-gly-suabu 6139:tolhs-ithiadiaz-gly-betapy 6140:phhs-oxadiaz-gly-zdaptb 6141: phhs-ithiadiaz-gly-betahcbph 6142: tolhs-me24oxaz-ala-psdap 6143: bhs-oxadiaz-gly-betahmph 6144: ibhs-ithiadiaz-bala-betamesu 6145: bim-52thiaz-ala-zdap 6146: bhs-24thioph-ala-beta34dcph 6147: ibhs-24thiaz-bala-ibsdap 6148: tolhs-ithiadiaz-bala-betabnaphth 6149: ibhs-oxadiaz-gly-betadcphtb 106150: tolhs-oxadiaz-bala-betafphe 6151: tolhs-nme35pyr-gly-betapytb 6152: bhs-53pyrazo-ala-betadcph 6153: 2py-26py-nmala-zdap 6154: bhs-25oxaz-gly-betaheph 156155: bhs-25thiaz-gly-betapym 6156: bhs-24thiaz-leu-betapy 6157: phhs-oxadiaz-bala-betadhbfu 6158: phhs-oxadiaz-bala-asppha 6159: bhs-25thioph-gly-betainyl 206160: tolhs-oxadiaz-gly-zdap 6161: irnpy-25thiaz-ala-betapy 6162: tolhs-25methiaz-gly-busu2be 6163: 2py-35thioph-leu-psdap 6164: phhs-25methiaz-bala-betabpy 256165: 2py-26py-gly-betabnaphth 6166: bhs-25methiaz-bala-betahbcph 6167: ibhs-24thioph-gly-betaipr 6168: bhs-oxadiaz-bala-betaimid 6169: impy-25oxaz-bala-betabdimo 306170: gua-24thiaz-gly-betapbiph 6171: tolhs-24thioph-gly-beta13bendi 6172: bhs-24thioph-bala-betabph 6173: bhs-24thiaz-bala-betaimid 6174: ibhs-24thioph-gly-betadhbfu 356175: tolhs-24thiaz-gly-betabediox 6176: phhs-25oxaz-gly-betatrif 6177: bhs-triaz-gly-zdap 6178:bhs-25thiaz-gly-beta4bph 6179:tolhs-25thiaz-bala-betabenfu 6180:bhs-24thiaz-gly-betaheph 6181:bhs-nme35pyr-leu-zdap 6182:impy-42nmeim-bala-betabpy 6183:bhs-25methiaz-bala-aspibua 6184:tolhs-25thiaz-gly-betainyl 6185:toihs-me24thioph-leu-betaph 6186:2py-ithiad iaz-g ly-zdap 6187:impy-25oxaz-gly-betafu2 6188:tolhs-me25oxaz-gly-beta34meoph 6189:thpy-24thiaz-gly-betadcph 6190:2py-25oxaz-gly-aspaba 6191:tolhs-24thiaz-bala-zdap 6192:thpym-2thioph-gly-zdap 6193:phhs-25thiaz-bala-betahcbph 6194:ibhs-25methiaz-gly-betapyr 6195:bhs-ithiadiaz-bala-betaimid 6196:2py-me25thiaz-bala-betadcph 6197:bhs-25thiaz-gly-betafbph 6198:phhs-24thiaz-gly-betahcbph 6199:phhs-25thiaz-gly-betabmph 6200:bhs-25oxaz-gly-betabenfu 6201:bhs-ithiadiaz-bala-betaanaphth 6202:bim-me24thioph-gly-betapy 6203:bhs-24thioph-ala-beta3quin 6204:tolhs-25oxaz-bala-betahdbph 6205:bhs-oxadiaz-gly-psdap 6206:bhs-25oxaz-bala-betatos 6207:ibhs-oxadiaz-bala-betapyr 6208:tolhs-me24thiaz-bala-beta34meoph 6209:2pmhs-25methiaz-gly-betameph 6210:phhs-25oxaz-gly-betah35dc 6211:hyd-42pym-gly-psdap 6212:ibhs-ithiadiaz-gly-betaet 6213:2py-me24thioph-gly-betapy 6214:phhs-24thiaz-gly-betahbcph 6215: phhs-oxadiaz-bala-zdap 6216: phhs-ithiadiaz-bala-betapyr 6217: phhs-24thioph-gly-asppha 6218: bhs-24thioph-bala-betaanaphth 6219: bhs-24thiaz-bala-betahbcph 6220: 2py-25methiaz-bala-zdap 6221: bhs-ithiadiaz-gly-betadbph 6222: 2pmhs-25methiaz-gly-betahbcph 6223: bhs-ithiadiaz-gly-betabpy 106224: bim-25thiaz-bala-betafphe 6225: phhs-24thiaz-bala-betahbcph 6226: ibhs-24thiaz-bala-betaimid 6227: bhs-25thiaz-bala-betadtrif 6228: bhs-35fur-ala-zdap 156229: bhs-ithiadiaz-bala-aspaba 6230: bhs-24thiaz-bala-betapytb 6231: tolhs-25oxaz-bala-beta23meoph 6232: bim-24thioph-bala-betafphe 6233: ibhs-24thioph-bala-betadcphtb 206234: bim-triaz-leu-zdap 6235: tolhs-25methiaz-bala-aspaba 6236: bhs-25oxaz-gly-zdapee 6237: bhs-nme35pyr-bala-betadhbfu 6238: ibhs-25oxaz-gly-betainyl 256239: phhs-me24thiaz-leu-betapy 6240: phhs-nme35pyr-bala-betatrif 6241: bhs-nme35pyr-gly-betapych 6242: bim-nme35pyr-gly-psdap 6243: phhs-ithiadiaz-gly-zdapch 306244: bhs-42oxaz-gly-psdap 6245: bhs-me24thiaz-ala-psdap 6246: tolhs-25methiaz-bala-betaet 6247: bhs-me24oxaz-bala-betadcph 6248: phhs-25methiaz-bala-betaoxope 356249: bhs-oxadiaz-gly-betabthioph 6250: tolhs-25methiaz-gly-betahdbph 6251: phhs-oxadiaz-gly-betabph WOOO166618 PCTlEP00103469 6252:ibhs-ithiadiaz-gly-betaphethioa 6253:tolhs-25oxaz-bala-beta35dbph 6254:tolhs-24thiaz-gly-betadbph 6255:ibhs-25oxaz-gly-betafbph 6256:impy-25thiaz-bala-betainyl 6257:2py-24thioph-gly-zdap 6258:phhs-oxadiaz-gly-psdaptb 6259:dhthi-25thiaz-bala-betadcph 6260:ibhs-24thiaz-gly-betafu3 106261:phhs-me24oxaz-ala-betadcph 6262:bhs-ithiadiaz-bala-betadtrif 6263:bhs-ithiadiaz-nmgly-beta34meoph 6264:bhs-24thiaz-gly-betapytb 6265:2py-24thioph-ala-psdap 156266:nmhs-26py-gly-betapy 6267:bim-26py-ala-psdap 6268:gua-26py-gly-betamesu 6269:2py-oxadiaz-bala-aspbzla 6270:phhs-24thioph-bala-betadcphch 206271:gua-42pym-gly-betacbph 6272:bhs-24thiaz-bala-betabpy 6273:phhs-ithiadiaz-bala-betainyl 6274:phhs-ithiadiaz-gly-betadcphch 6275:phhs-25thiaz-bala-betahph 256276:ibhs-25methiaz-bala-betapyee 6277:ibhs-24thiaz-gly-aspbzla 6278:phhs-24thiaz-bala-betaoxope 6279:ibhs-24thioph-bala-betaphethioa 6280:tolhs-ithiadiaz-gly-betamethi 306281:bim-24thiaz-gly-betainyl 6282:phhs-25oxaz-bala-betapym 6283:tolhs-me24oxaz-bala-zdap 6284:bhs-25thioph-bala-betapy 6285:tolhs-24thioph-bala-betaimid 356286:bim-25thiaz-gly-aspbzla 6287:tolhs-ithiadiaz-gly-betadtrif 6288:ibhs-24thiaz-bala-betaftrif 6289:2py-thiadiaz-bala-psdap 6290:phhs-25oxaz-bala-betabmph 6291:phhs-nme35pyr-gly-betahmph 6292:2py-53pyrazo-gly-betadcph 6293:bhs-me24thiaz-leu-psdap 6294:bim-24im-gly-betadcph 6295:2py-24oxaz-ala-betameph 6296:tolhs-24thiaz-gly-betahbcph 6297:phhs-25methiaz-bala-beta35dbph 6298:phhs-25thiaz-gly-betapyr 6299:ibhs-25thiaz-bala-betadbph 6300:bhs-nme35pyr-bala-betaet 6301:bim-me25thiaz-gly-zdap 6302:phhs-25thiaz-bala-betaanaphth 6303:bhs-nme35pyr-gly-betaol 6304:phhs-24thioph-bala-betadtrif 6305:phhs-me25thiaz-leu-beta34meoph 6306:ibhs-25thiaz-gly-betamethi 6307:bim-24thioph-leu-zdap 6308:bhs-ithiadiaz-bala-betathio3 6309:2pmhs-24thiaz-gly-betabpy 6310:bhs-24thiaz-gly-betapym 6311:phhs-25methiaz-gly-betampy 6312:bim-25oxaz-bala-asppha 6313:impy-42nmeim-gly-betamethioph 6314:tolhs-nme35pyr-bala-betahcbph 6315:bhs-oxadiaz-bala-betabnaphth 6316:bhs-nme35pyr-gly-betaipr 6317:ibhs-24thiaz-bala-betahc 6318:tolhs-25methiaz-gly-betaanaphth 6319:2py-me25thioph-bala-betaph 6320:tolhs-24thioph-gly-betapych 6321:ibhs-oxadiaz-gly-betabenfu 6322:phhs-25thiaz-gly-betamesu 6323:tolhs-me24thioph-bala-betaph 6324:dimethpym-26py-gly-betahdcph 6325:ibhs-25thiaz-gly-beta34meoph 6326: bim-me25thiaz-gly-betapy 6327: phhs-24thioph-gly-betapym 6328: 2py-me25thiaz-ala-beta34meoph 6329: phhs-oxadiaz-bala-betadbph 6330: ibhs-nme35pyr-bala-betafbph 6331: ibhs-25thiaz-bala-betatrif 6332: tolhs-oxadiaz-gly-betaipr 6333: bim-me25thiaz-bala-betapy 6334: bhs-25oxaz-gly-betahc 106335: ibhs-24thioph-bala-betadtrif 6336: bhs-nme35pyr-gly-betahmo 6337: 2py-52thiaz-gly-betadcph 6338: bhs-35fur-leu-betadcph 6339: dhim-26py-gly-betainyl 156340: bim-me24thiaz-ala-zdap 6341: ibhs-nme35pyr-gly-betamesu 6342: ibhs-oxadiaz-bala-aspibua 6343: tolhs-24thiaz-bala-psdapee 6344: bim-me24oxaz-bala-psdap 206345: bhs-me24thioph-gly-psdap 6346: bhs-24thioph-gly-betaet 6347: ibhs-ithiadiaz-bala-beta23meoph 6348: 2py-25thiaz-bala-suabu 6349: bhs-me24thiaz-bala-betadcph 256350: 2py-25thiaz-bala-betaet 6351: bhs-oxadiaz-gly-asppha 6352: ibhs-24thioph-bala-beta13bendi 6353: phhs-25methiaz-bala-betabnaphth 6354: 2py-25thiaz-gly-betacthioph 306355; dhim-25oxaz-bala-betadcph 6356: phhs-me24thioph-bala-psdap 6357: 2py-ithiadiaz-bala-aspibua 6358: phhs-24thioph-gly-betadmoph 6359: bhs-ithiadiaz-bala-betadcphch 356360: ibhs-24thiaz-bala-betadmoph 6361: phhs-24thioph-bala-beta4bph 6362: ibhs-25oxaz-bala-betapych 6363: ibhs-24thioph-bala-betabph 6364: bhs-25oxaz-ala-betapy 6365: bim-25fur-leu-betapy 6366: ibhs-24thioph-bala-beta35dbph 6367: bhs-24thioph-bala-betaftrif 6368: bhs-25fur-ala-zdap 6369: bhs-25thiaz-baia-beta34meoph 6370: thazep-26py-gly-betapy 6371: bhs-nme35pyr-gly-betathio3 6372:2pmhs-25oxaz-bala-betaoxope 6373: tolhs-oxadiaz-gly-betacph 6374: phhs-25methiaz-bala-psdaptb 6375: bim-25thiaz-nmala-betadcph 6376: bim-25thiaz-bala-aspbzla 6377:bhs-24thiaz-nmgly-betafphe 6378: tolhs-ithiadiaz-gly-betaph 6379: ibhs-ithiadiaz-bala-betaol 6380: impy-24thioph-gly-betathiobe 6381: tolhs-25methiaz=gly-betacthioph 6382:ibhs-24thiaz-bala-betameph 6383: 2py-25methiaz-bala-betaet 6384: bhs-25oxaz-nmgly-beta34meoph 6385: gua-24thiaz-gly-betapy 6386: tolhs-25oxaz-bala-betahcbph 6387:bhs-42nmeim-bala-betacthioph 6388; tolhs-25methiaz-gly-betameph 6389: ibhs-25thiaz-bala-betathiome 6390: bhs-nme35pyr-bala-betathio3 6391: phhs-oxadiaz-bala-betahmofu 6392:ibhs-ithiadiaz-bala-betadmoph 6393: tolhs-24thiaz-gly-aspaba 6394: impy-25thiaz-bala-betamesu 6395: ibhs-24thiaz-gly-betaibph 6396; bhs-25oxaz-bala-betainyl 6397:bhs-25methiaz-bala-betahph 6398: gua-25thiaz-nmgly-betapy 6399: bhs-24thioph-gly-aspbzla 6400: bhs-25oxaz-nmgly-ibsdap 6401: 2py-24im-leu-zdap 6402: phhs-nme35pyr-bala-betafbph 6403: tolhs-25oxaz-bala-zdap 6404: phhs-oxadiaz-gly-betahmofu 6405: bim-42nmeim-bala-betathiobe 6406: bhs-25oxaz-bala-zdaptb 6407: ibhs-25thiaz-gly-aspbzla 6408: bim-24oxaz-bala-betapy 106409: ibhs-25oxaz-gly-beta13bendi 6410: bhs-24thiaz-gly-betahbcph 6411: ibhs-25methiaz-bala-betapbiph 6412: tolhs-ithiadiaz-bala-betadito 6413: phhs-ithiadiaz-bala-betatrif 156414: tolhs-24thiaz-gly-betadcphch 6415: bim-25methiaz-bala-betacph 6416: phhs-25methiaz-gly-betamethioph 6417: tolhs-25methiaz-gly-betapyr 6418: bhs-ithiadiaz-gly-psdaptb 206419: ibhs-ithiadiaz-bala-betapyr 6420: phhs-24thioph-bala-betahdbph 6421: dlhim-42pym-ala-betapy 6422: bhs-25thiaz-ala-betambiph 6423: 2py-24thioph-gly-asppha 256424: phhs-24thiaz-bala-betafph 6425: 2py-24thiaz-bala-betaet 6426: tolhs-ithiadiaz-bala-betahph 6427: 2py-nme35pyr-ala-betadcph 6428: phhs-me24thioph-bala-betaph 306429: bhs-25oxaz-gly-betaoxope 6430: phhs-24thiaz-gly-betaimid 6431: tolhs-25methiaz-gly-betafphe 6432: bhs-35thioph-leu-betapy 6433: ibhs-25thiaz-bala-betadcphch 356434: toihs-25thiaz-bala-betatbuph 6435: bhs-24im-gly-betadcph 6436: 2py-26py-gly-betameph W000166618 PCTIEPOOl03469 6437: hs-25thioph-gly-zdap 6438: phhs-me24oxaz-gly-zdap 6439. tolhs-25oxaz-bala-betadhbfu 6440: bhs-24thioph-bala-betabdimo 6441: ibhs-ithiadiaz-bala-betahdbph 6442: phhs-24thioph-bala-betapym 6443: phhs-25methiaz-g1y-betadcphee 6444: bhs-25methiaz-gly-betahph 6445: phhs-24thiaz-bala-betaheph 6446: bhs-25oxaz-gly-betaoxaz 6447: bhs-24thiaz-bala-aspibua 6448: phhs-ithiadiaz-gly-betabthioph 6449: agua-26py-gly-betainyl 6450: phhs-24thioph-gly-betahmofu 6451: bhs-oxadiaz-bala-betatrif 6452: bhs-me24thioph-ala-betaph 6453: tolhs-25methiaz-gly-betabediox 6454: tolhs-24thioph-bala-betabediox 6455: bhs-24thioph-gly-betambiph 6456: bim-35fur-leu-betapy 6457: phhs-24thiaz-gly-csdap 6458: agua-42nmeim-gly-betapy 6459: tolhs-me24thioph-ala-psdap 6460: tolhs-ithiadiaz-bala-betabdimo 6461: tolhs-me25oxaz-gly-betaph 6462: 2py-oxadiaz-gly-asppha 6463: tolhs-25thiaz-gly-betahph 6464: bhs-nme35pyr-gly-betahdbph 6465: bhs-24thiaz-gly-ibsdap 6466: phhs-nme35pyr-gly-beta4bph 6467: bhs-25oxaz-bala-betathiome 6468: tolhs-25thiaz-bala-betaamibe 6469: tolhs-25oxaz-bala-zdapee 6470: impy-25thiaz-bala-betaftrif 6471: tolhs-25oxaz-gly-betadcphtb 6472: bhs-me24thioph-bala-psdap 6473: bhs-nme35pyr-nmgly-betathio3 6474: bhs-oxadiaz-gly-betapym 6475: phhs-24thioph-gly-betadito 6476: ibhs-25oxaz-bala-betapbiph 6477: tolhs-nme35pyr-bala-betatrif 6478: bhs-25methiaz-bala-beta34dcph 6479: bim-25methiaz-gly-betadmph 6480: phhs-25methiaz-gly-betahc 6481: tolhs-24thiaz-bala-betah35dc 6482: bhs-me25thioph-ala-betaph 6483:tolhs-oxadiaz-gly-betahmph 6484: tolhs-25thiaz-bala-betatos 6485: tolhs-ithiadiaz-gly-betaol 6486: tolhs-24thioph-bala-betadmoph 6487: tolhs-oxadiaz-gly-betainyl 6488:phhs-25methiaz-bala-beta4bph 6489: bim-thiadiaz-ala-betadcph 6490: ur-25methiaz-gly-betadcph 6491: bim-42nmeim-nmgly-zdap 6492: tolhs-24thiaz-bala-betaph 6493:ibhs-24thioph-gly-betapyee 6494: thazep-24oxaz-gly-betainyl 6495: 4pmhs-25thiaz-bala-betameph 6496: ibhs-25methiaz-gly-suabu 6497: tolhs-25thiaz-bala-betapym 6498:bhs-oxadiaz-gly-beta23meoph 6499: tolhs-nme35pyr-gly-psdap 6500: 2pmhs-42nmeim-gly-betahmo 6501: phhs-ithiadiaz-bala-betaomebendi 6502: bhs-me24thiaz-ala-beta34meoph 6503:bhs-24thiaz-bala-beta3quin 6504: phhs-25methiaz-gly-betathioph 6505: tolhs-me25oxaz-gly-betapy 6506: phhs-24thioph-gly-betapyr 6507: tolhs-25oxaz-bala-betapym 6508:bhs-ithiadiaz-gly-betaph 6509: bim-25oxaz-leu-psdap 6510: impy-24thioph-bala-betaftrif 6511: phhs-24thioph-gly-betah35dc 6512; ibhs-24thiaz-gly-betadmoph 6513: bhs-42oxaz-ala-betapy 6514: thazep-42nmeim-bala-betameph 6515: bhs-24thiaz-bala-busu2be 6516: gua-25thiaz-gly-betahph 6517: gua-24thiaz-gly-betainyl 6518: bhs-25thiaz-gly-betahmofu 6519: phhs-nme35pyr-gly-betahmo 6520:bhs-25thiaz-gly-betaamibe 6521: phhs-24thioph-gly-betapy 6522: bhs-oxadiaz-gly-betadmph 6523: tolhs-me24oxaz-ala-betadcph 6524: thazep-25methiaz-bala-zdap 6525:tolhs-ithiadiaz-bala-aspibua 6526: phhs-me25oxaz-bala-zdap 6527: phhs-nme35pyr-gly-betadito 6528: 2py-24oxaz-bala-psdap 6529: bhs-25methiaz-bala-beta35dbph 6530:phhs-24thioph-bala-zdaptb 6531: bhs-35fur-gly-betadcph 6532: phhs-25thiaz-gly-beta34meoph 6533: phhs-25thiaz-gly-betaphethio 6534: agua-24oxaz-gly-betainyl 6535:phhs-25oxaz-bala-betahc 6536: 2py-53pyrazo-leu-zdap 6537: ibhs-25methiaz-bala-aspibua 6538: 2py-24thiaz-gly-betapy 6539: tolhs-ithiadiaz-gly-betaphethio 6540:ibhs-oxadiaz-bala-betaipr 6541: bhs-25thiaz-gly-betathio3 6542: gua-24oxaz-gly-betacbph 6543: bhs-24oxaz-gly-betapy 6544: tolhs-24thioph-bala-betafu2 6545:phhs-24thioph-gly-betamethi 6546: bhs-nme35pyr-bala-beta34dcph 6547: phhs-oxadiaz-bala-betaheph 6548:2py-oxadiaz-gly-betapy 6549:bhs-25methiaz-nmgly-betameph 6550:2py-me24oxaz-ala-betadcph 6551:bim-triaz-ala-psdap 6552:ibhs-25thiaz-gly-betabenfu 6553:bim-42nmeim-bala-betapy 6554:bhs-25thiaz-gly-betabnaphth 6555:bhs-ithiadiaz-bala-betadhbfu 6556:tolhs-25thiaz-gly-betaipro 6557:dhpyrr-26py-gly-psdap 6558:bhs-24thiaz-ala-betadcph 6559:hs-25thiaz-gly-betainyl 6560:bhs-25oxaz-gly-betamethi 6561:bhs-nme35pyr-bala-beta34meoph 6562:ibhs-25methiaz-bala-betaomebendi 6563:phhs-24thioph-gly-betadcphtb 6564:ibhs-25thiaz-gly-betatbuph 6565:ibhs-oxadiaz-gly-betafluo 6566:2pmhs-24thiaz-phe-zdap 6567:ibhs-24thioph-gly-betabph 6568:2py-42nmeim-gly-betaimid 6569:ibhs-25methiaz-gly-betahni 6570:phhs-25methiaz-bala-psdapch 6571:phhs-25oxaz-gly-betabpy 6572:bhs-24thiaz-nmgly-beta13bendi 6573:ibhs-oxadiaz-gly-betabediox 6574:ibhs-nme35pyr-gly-betacph 6575:bim-24im-leu-psdap 6576:bim-25thiaz-gly-betaomebendi 6577:tolhs-oxadiaz-gly-zdapee 6578:ibhs-24thioph-gly-betahcbph 6579:ibhs-25methiaz-bala-betainyl 6580:ibhs-ithiadiaz-bala-zdapee 6581:tolhs-ithiadiaz-bala-betahc 6582:tolhs-24thioph-gly-betamesu 6583:tolhs-24thiaz-bala-suabu 6584:bhs-24im-ala-betadcph 6585:gua-24thiaz-gly-beta4bph 6586:bhs-25thiaz-bala-betaipr 6587:ibhs-25oxaz-gly-betabnaphth 6588:ibhs-nme35pyr-gly-betadito 6589:bim-me25thiaz-ala-zdap 6590:bhs-24thioph-bala-zdapee 6591:ibhs-oxadiaz-giy-betafu2 6592:2py-me25thiaz-leu-betapy 6593:phhs-24thiaz-bala-betaipr 6594:tolhs-ithiadiaz-bala-betafluo 6595:ibhs-24thioph-bala-betaamibe 6596:2py-25thioph-gly-betapy 6597:bhs-25oxaz-leu-betapy 6598:tolhs-ithiadiaz-gly-betaamibe 6599:bhs-me24oxaz-leu-betadcph 6600:bhs-nme35pyr-bala-betafluo 6601:bhs-24thiaz-ala-betabpy 6602:ibhs-25methiaz-bala-betaipr 6603:bhs-24thiaz-bala-betadhbfu 6604:tolhs-25thiaz-gly-beta13bendi 6605:phhs-nme35pyr-gly-betadcphee 6606:bhs-25oxaz-gly-betabmph 6607:phhs-25methiaz-gly-betaipr 6608:tolhs-25oxaz-gly-betaftrif 6609:bhs-25oxaz-bala-betaphethioa 6610:ibhs-24thioph-gly-betaheph 6611:bhs-24thioph-gly-suabu 6612:tolhs-25methiaz-bala-betamethioph 6613:tolhs-24thioph-gly-asppha 6614:ibhs-25methiaz-bala-betaol 6615:phhs-24thiaz-bala-betapytb 6616:2pmhs-42nmeim-bala-betafu2 6617:tolhs-oxadiaz-gly-aspibua 6618:bhs-oxadiaz-nmgly-ibsdap 6619:tolhs-24thioph-gly-betapym 6620:ibhs-nme35pyr-bala-betahmofu 6621:bhs-35thioph-bala-zdap 6622: 2pmhs-25methiaz-gly-betahb 6623: gua-26py-gly-betah35dc 6624: phhs-24thiaz-gly-betapytb 6625: bim-42nmeim-gly-betaphethioa 6626: 2py-triaz-gly-zdap 6627: bhs-24thiaz-gly-zdap 6628: bhs-24thiaz-bala-betampy 6629: bim-25oxaz-gly-asppha 6630: tolhs-ithiadiaz-bala-beta35dbph 106631: phhs-nme35pyr-bala-asppha 6632: ibhs-oxadiaz-gly-betadhbfu 6633: ibhs-ithiadiaz-bala-betadcphch 6634: 2py-ithiadiaz-gly-aspaba 6635: bhs-25oxaz-nmgly-beta3quin 156636: ibhs-25oxaz-bala-zdapee 6637: bhs-25oxaz-gly-betabthioph 6638: bhs-oxadiaz-gly-betabph 6639: phhs-oxadiaz-bala-betameph 6640: tolhs-me25thioph-bala-betapy 206641: tolhs-ithiadiaz-gly-betahdbph 6642: bim-24thiaz-gly-betadcph 6643: ibhs-nme35pyr-gly-betaphethioa 6644: tolhs-25thiaz-gly-betathio3 6645: phhs-24thioph-bala-betapych 256646: 2py-35fur-leu-betapy 6647: bhs-24chin-gly-zdap 6648: tolhs-oxadiaz-gly-betaamibe 6649: bhs-24thioph-nmgly-betahph 6650: ibhs-oxadiaz-gly-betabdimo 306651: 2py-me24oxaz-gly-beta34meoph 6652: bhs-25thiaz-gly-betaimid 6653: bim-24thiaz-ala-betadcph 6654: tolhs-25oxaz-gly-zdap 6655: bhs-ithiadiaz-gly-betacbph 356656: tolhs-nme35pyr-gly-beta13bendi 6657: 2py-thiadiaz-bala-betapy 6658: dhim-24oxaz-gly-psdap 6659: bhs-nme35pyr-bala-psdap 6660: tolhs-oxadiaz-bala-psdapee 6661: gua-25thiaz-gly-betadmoph 6662: bhs-me24thioph-ala-betadcph 6663: bhs-25methiaz-gly-betapbiph 6664: bhs-25oxaz-bala-betadcphch 6665: ibhs-ithiadiaz-bala-betadmph 6666: bim-23thioph-gly-zdap 6667: phhs-24thiaz-bala-betahb 6668: tolhs-25methiaz-gly-betapy 6669: bhs-24thioph-met-betadcph 6670: tolhs-24thioph-bala-betapych 6671: 2py-25thioph-leu-betapy 6672: ibhs-25oxaz-bala-asppha 6673: phhs-me24oxaz-bala-zdap 6674: ibhs-25oxaz-bala-betabnaphth 6675: tolhs-24thioph-gly-betapbiph 6676: bhs-ithiadiaz-leu-betapy 6677: bhs-25oxaz-bala-zdap 6678: phhs-25methiaz-gly-betahcbph 6679: tolhs-24thiaz-bala-betahmph 6680: tolhs-nme35pyr-gly-betabpy 6681: ibhs-25methiaz-gly-betaphethio 6682: tolhs-oxadiaz-bala-betahc 6683: phhs-25oxaz-bala-zdaptb 6684: ibhs-nme35pyr-bala-betabnaphth 6685: ibhs-25methiaz-gly-aspbzla 6686. tolhs-24thiaz-bala-betafluo 6687: bhs-ithiadiaz-nmgly-betacph 6688: tolhs-25oxaz-bala-betaipro 6689: bim-25thioph-leu-betapy 6690: ibhs-oxadiaz-bala-betathiobe 6691: gua-24thiaz-gly-betathiome 6692: bhs-25thioph-ala-betadcph 6693: 2py-24oxaz-ala-betapy 6694: phhs-25methiaz-bala-betahcbph 6695: ibhs-25thiaz-bala-betathioph W000166618 PCTlEP0010346g 6696:ibhs-25oxaz-bala-betapytb 6697:phhs-25thiaz-gly-suabu 6698:phhs-me25thioph-bala-zdap 6699:phhs-oxadiaz-gly-betahmo 6700:bhs-25thiaz-gly-betabpy 6701:phhs-24thiaz-bala-betainyl 6702:phhs-24thiaz-bala-betaph 6703:bhs-25methiaz-nmgly-betainyl 6704:bhs-nme35pyr-gly-betabpy 6705:bhs-25methiaz-bala-betadtrif 6706:phhs-24thiaz-bala-betafluo 6707:2py-25thiaz-bala-zdap 6708;2py-25oxaz-bala-asppha 6709:tolhs-25methiaz-bala-betafu2 6710:bhs-25thiaz-bala-beta34dcph 6711:2py-25oxaz-ala-betadcph 6712:bhs-25methiaz-bala-zdap 6713:phhs-oxadiaz-gly-betamethi 6714:phhs-ithiadiaz-bala-betamesu 6715:bhs-24thiaz-bala-betamethioph 6716:bhs-25oxaz-gly-betapym 6717:bhs-ithiadiaz-ala-betainyl 6718:phhs-24thioph-gly-betabmph 6719:ibhs-25methiaz-gly-betadmph 6720;ibhs-24thiaz-bala-betahmo 6721:tolhs-24thiaz-gly-beta34dcph 6722:phhs-25methiaz-gly-betaphethioa 6723:2py-me25oxaz-leu-betaph 6724:phhs-ithiadiaz-bala-betathioph 6725:bhs-me25thiaz-leu-betadcph 6726:bhs-25oxaz-bala-betaol 6727:bhs-24thiaz-nmgly-betaanaphth 6728:ibhs-24thioph-bala-betamethioph 6729:phhs-25methiaz-bala-betamethi 6730:ibhs-nme35pyr-gly-zdapee 6731:bhs-24thioph-bala-beta13bendi 6732:ibhs-25oxaz-bala-psdapch 6733: ibhs-ithiadiaz-gly-betaoxope 6734: tolhs-25thiaz-gly-betaol 6735: tolhs-nme35pyr-gly-betadtrif 6736: bhs-26py-ala-betadcph 6737: tolhs-25thiaz-gly-betadcphtb 6738: impy-25methiaz-gly-betabediox 6739: bhs-25thioph-ala-betapy 6740: phhs-25thiaz-gly-betadito 6741: phhs-oxadiaz-gly-beta34dcph 6742: bim-25oxaz-gly-betabpy 6743: ibhs-25methiaz-bala-betadcph 6744: tolhs-25methiaz-bala-ibsdap 6745: phhs-oxadiaz-gly-betaftrif 6746: tolhs-oxadiaz-gly-betaoxaz 6747: 2py-thiadiaz-leu-zdap 6748: tolhs-me24thioph-leu-zdap 6749: ibhs-oxadiaz-bala-betaoxope 6750: bhs-ithiadiaz-gly-betaanaphth 6751: thazep-24thiaz-gly-betainyl 6752: tolhs-ithiadiaz-gly-betaipr 6753: bhs-35thioph-ala-psdap 6754: bhs-24thioph-bala-betapytb 6755: bhs-me25thiaz-ala-betapy 6756: bhs-25oxaz-gly-betaipro 6757: ibhs-25methiaz-bala-betahbcph 6758: bim-52thiaz-gly-betainyl 6759: ibhs-24thioph-bala-betafph 6760: 2py-25thioph-leu-zdap 6761: ibhs-25oxaz-bala-betaet 6762: bhs-me25thiaz-leu-betapy 6763: ibhs-25oxaz-gly-betabediox 6764: ibhs-nme35pyr-bala-betabpy 6765: phhs-24thioph-bala-betafph 6766: tolhs-25methiaz-gly-betah35dc 6767: tolhs-25oxaz-bala-aspibua 6768: 2py-oxadiaz-gly-zdap 6769: bhs-ithiadiaz-leu-psdap 6770:2 py-24oxaz-g ly-psd a p 6771:bhs-46pym-gly-betameph 6772:tolhs-ithiadiaz-bala-zdapch 6773:ibhs-25oxaz-gly-betathiome 6774:bhs-25oxaz-nmgly-betadmoph 6775:tolhs-25oxaz-bala-betahbcph 6776:ibhs-25oxaz-bala-betaphethio 6777:phhs-nme35pyr-bala-betadhbfu 6778:bhs-me24thioph-ala-zdap 6779:bhs-triaz-leu-psdap 6780:ibhs-24thioph-bala-aspibua 6781:bhs-24py-gly-betapy 6782:gua-25thiaz-gly-beta4bph 6783:ibhs-oxadiaz-bala-betabdimo 6784:gua-24thiaz-gly-betambiph 6785:bhs-nme35pyr-ala-beta23meoph 6786:bhs-24thioph-bala-betatbuph 6787:bhs-nme35pyr-bala-zdap 6788:ibhs-24thioph-bala-betafphe 6789:phhs-24thiaz-bala-aspbzla 6790;ibhs-ithiadiaz-gly-aspbzla 6791:bhs-24thiaz-bala-betaol 6792:bhs-25methiaz-gly-betadtrif 6793:ibhs-25methiaz-bala-betaanaphth 6794:tolhs-25oxaz-gly-betamethi 6795:phhs-oxadiaz-bala-betahb 6796:2py-me25thiaz-bala-zdap 6797:bhs-24thiaz-gly-betainyl 6798:impy-25thiaz-bala-busu2be 6799:bhs-24thioph-gly-betadbph 6800:ibhs-oxadiaz-gly-aspibua 6801:2py-25fur-leu-zdap 6802:ibhs-25thiaz-gly-betafbph 6803:tolhs-ithiadiaz-bala-betabediox 6804:impy-24thioph-bala-betafu3 6805:phhs-25methiaz-gly-beta35dbph 6806:tolhs-me24thioph-bala-beta34meoph 6807: bhs-oxadiaz-bala-betafphe 6808: tolhs-oxadiaz-bala-betafu2 6809: cima-25thiaz-gly-betainyl 6810: bhs-25oxaz-bala-betahph 6811:ibhs-25oxaz-bala-betatos 6812: ibhs-25thiaz-bala-betacbph 6813: gua-42pym-gly-betaol 6814: tolhs-ithiadiaz-bala-psdap 6815: 2py-26py-gly-betainyl 6816:bhs-24thioph-gly-betadhbfu 6817: tolhs-ithiadiaz-bala-betabph 6818: tolhs-24thioph-bala-betaheph 6819: phhs-25thiaz-gly-betabnaphth 6820: tolhs-25thiaz-bala-betathiobe 6821:bhs-oxadiaz-ala-beta34dcph 6822: phhs-me24oxaz-leu-betaph 6823: bhs-24thiaz-nmgly-betadito 6824: phhs-oxadiaz-gly-betahni 6825: 2py-25oxaz-bala-betamesu 6826:ibhs-nme35pyr-bala-betathiobe 6827: bhs-24thioph-gly-betaheph 6828: phhs-24thiaz-gly-zdapee 6829: ibhs-nme35pyr-gly-betadcphch 6830: tolhs-24thiaz-gly-betatos 6831:tolhs-ithiadiaz-bala-betahmo 6832: bhs-me24thiaz-gly-betameph 6833: dhim-me25thiaz-ala-betameph 6834: ibhs-24thiaz-bala-betampy 6835: ibhs-25oxaz-bala-psdaptb 6836:tolhs-25thiaz-bala-betampy 6837: ibhs-nme35pyr-g!y-betampy 6838: tolhs-me25thiaz-gly-zdap 6839: tolhs-25thiaz-bala-betaftrif 6840: ibhs-24thiaz-gly-betafbph 6841:bhs-oxadiaz-ala-betadmph 6842: tolhs-oxadiaz-bala-betadito 6843: tolhs-25thiaz-bala-betamesu 6844:tolhs-25oxaz-gly-betadcphee 6845:gua-25thiaz-gly-beta35dbph 6846:tolhs-nme35pyr-gly-betaphethio 6847:gua-24oxaz-gly-beta34dcph 6848:2py-24thiaz-ala-zdap 6849:tolhs-oxadiaz-gly-betafphe 6850:tolhs-25oxaz-gly-beta23meoph 6851:ibhs-24thiaz-bala-beta23meoph 6852:phhs-nme35pyr-gly-betahc 6853:gua-24oxaz-gly-betadmph 6854:bhs-25fur-gly-psdap 6855:bhs-24thiaz-gly-betadbph 6856:ibhs-25thiaz-gly-betabph 6857:2py-triaz-ala-psdap 6858:tolhs-ithiadiaz-bala-csdap 6859:tolhs-ithiadiaz-gly-betadito 6860:tolhs-24thiaz-gly-betapyr 6861:bhs-ithiadiaz-gly-betafluo 6862:tolhs-24thioph-gly-betafu2 6863:ibhs-24thioph-gly-betathioph 6864:2py-53pyrazo-bala-betadcph 6865:tolhs-oxadiaz-bala-betabenfu 6866.tolhs-25thiaz-bala-betahmo 6867:ibhs-oxadiaz-gly-betahb 6868:bhs-25thiaz-ala-betameph 6869:phhs-ithiadiaz-gly-betathiome 6870:phhs-oxadiaz-g1y-betadbph 6871:tolhs-25oxaz-gly-betaoxope 6872:bhs-oxadiaz-bala-betadbph 6873:bhs-ithiadiaz-bala-betadcphee 6874:bhs-me24oxaz-gly-betadcph 6875:tolhs-25thiaz-gly-betaphethioa 6876:dhim-26py-ala-betameph 6877:tolhs-oxadiaz-gly-psdap 6878:tolhs-oxadiaz-bala-betahcbph 6879:bim-24thiaz-bala-aspbzla 6880:phhs-24thioph-gly-beta34dcph W000166618 PCTlEP00103469 6881:bim-42oxaz-leu-zdap 6882:phhs-25oxaz-bala-betathiobe 6883:tolhs-24thiaz-bala-betathio3 6884:2py-35thioph-bala-zdap 6885:bim-25fur-bala-zdap 6886:bim-me25thioph-leu-psdap 6887:ibhs-25thiaz-gly-betafu2 6888:bhs-24thiaz-gly-betaamibe 6889:2pmhs-24thiaz-gly-betameph 6890:ibhs-24thioph-gly-psdapee 6891:phhs-25methiaz-gly-psdapch 6892:ibhs-24thiaz-gly-suabu 6893:bhs-25thiaz-ala-betapy 6894:dhim-52thiaz-ala-psdap 6895:tolhs-25thiaz-gly-zdaptb 6896:ibhs-24thiaz-gly-aspibua 6897:2pmhs-42nmeim-bala-beta23meoph 6898:2py-52thiaz-gly-betapy 6899:bhs-ithiadiaz-gly-betathiome 6900:bhs-ithiadiaz-bala-betabnaphth 6901:2py-24oxaz-leu-zdap 6902:tolhs-24thioph-bala-betaphethio 6903:bhs-35fur-gly-zdap 6904:hts-25thiaz-gly-betapy 6905:2py-oxadiaz-bala-aspibua 6906:tolhs-nme35pyr-gly-betabdcph 6907:ibhs-ithiadiaz-bala-psdaptb 6908:ibhs-25methiaz-bala-betacbph 6909:2py-25oxaz-bala-busu2be 6910:bim-me25thiaz-leu-betaph 6911:phhs-25thiaz-bala-betaphethioa 6912:ibhs-ithiadiaz-bala-betafluo 6913:gua-25thioph-gly-betadcph 6914:bhs-25thiaz-bala-betaomebendi 6915:phhs-25methiaz-bala-betaet 6916:2pmhs-42nmeim-bala-betahdbph 6917:bhs-35thioph-gly-zdap 6918:ibhs-oxadiaz-bala-ibsdap 6919:tolhs-24thiaz-gly-betaanaphth 6920:2py-me24oxaz-leu-betadcph 6921:phhs-25methiaz-bala-psdapee 6922:pahs-42nmeim-bala-betadcph 6923:ibhs-oxadiaz-bala-betaol 6924:ibhs-25thiaz-gly-betapych 6925:bhs-42nmeim-leu-psdap 6926:tolhs-nme35pyr-gly-betadmoph 106927:phhs-24thioph-gly-ibsdap 6928:tolhs-me25thioph-gly-psdap 6929:phhs-25oxaz-gly-betaoxope 6930:bhs-oxadiaz-gly-aspaba 6931:tolhs-25thiaz-bala-betafluo 156932:tolhs-25methiaz-gly-betahb 6933:tolhs-ithiadiaz-gly-psdapee 6934:2py-42nmeim-gly-betahc 6935:tolhs-25thiaz-gly-betaphethio 6936:bhs-ithiadiaz-bala-betamethi 206937:tolhs-25methiaz-gly-betabph 6938:bhs-24thioph-gly-betaanaphth 6939:phhs-25methiaz-gly-beta34meoph 6940:tolhs-25methiaz-gly-betadmoph 6941:bhs-24thiaz-gly-betadmph 256942:2py-24thioph-gly-beta35dbph 6943:ibhs-25oxaz-gly-betabmph 6944:bhs-ithiadiaz-bala-beta34meoph 6945:bim-42oxaz-ala-betadcph 6946:tolhs-25methiaz-gly-betathiome 306947:ibhs-nme35pyr-bala-csdap 6948:bhs-ithiadiaz-ala-betamesu 6949:thpym-26py-gly-betahdcph 6950:2py-ithiadiaz-bala-betapy 6951;tolhs-oxadiaz-gly-asppha 356952:bhs-nme35pyr-nmgly-betaanaphth 6953:phhs-25thiaz-bala-betahmo 6954:bhs-25oxaz-gly-betadhbfu 6955:bhs-24thiaz-nmgly-betacthioph 6956:tolhs-25thiaz-bala-ibsdap 6957:tolhs-nme35pyr-bala-beta23meoph 6958:bim-24thioph-gly-betadcph 6959:tolhs-24thioph-bala-betahc 6960:bhs-25thiaz-bala-betahcbph 6961:tolhs-24thiaz-bala-betadhbfu 6962:ibhs-25methiaz-bala-betadtrif 6963:phhs-25methiaz-bala-beta23meoph 6964:phhs-nme35pyr-bala-betampy 6965:bhs-25thiaz-gly-betahcbph 6966:bhs-ithiadiaz-ala-zdap 6967:tolhs-25thiaz-bala-betaimid 6968:phhs-25thiaz-gly-betaamibe 6969:bim-ithiadiaz-ala-betapy 6970:bhs-42pym-ala-betainyl 6971:tolhs-25thiaz-bala-betafu2 6972:2pmhs-24thioph-gly-betathiome 6973:imhs-24thiaz-giy-zdap 6974:dhim-52thiaz-gly-betapy 6975:tolhs-24thioph-bala-betamesu 6976:phhs-ithiadiaz-bala-betahmo 6977:gua-25thiaz-gly-betaibph 6978:ibhs-24thiaz-bala-betadito 6979:phhs-nme35pyr-gly-betambiph 6980:dhpyrr-25thioph-gly-betapy 6981:bhs-25thiaz-nmgly-beta13bendi 6982:bhs-42nmeim-gly-betaoxope 6983:bim-42pym-ala-betadcph 6984:tolhs-me24thioph-leu-psdap 6985:2py-42nmeim-leu-betapy 6986:phhs-oxadiaz-bala-betamesu 6987:tolhs-24thioph-bala-aspaba 6988:dhim-26py-ala-zdap 6989:bhs-oxadiaz-bala-betampy 6990:ibhs-25thiaz-bala-betamethioph 6991:2py-42pym-gly-betameph 6992:tolhs-ithiadiaz-bala-betadmph 6993:gua-24thiaz-gly-betahmo 6994:bhs-ithiadiaz-bala-betapym 6995:bhs-24thioph-ala-betacthioph 6996:bhs-24thiaz-bala-beta.hph 6997:phhs-ithiadiaz-gly-betadito 6998:phhs-me24oxaz-ala-betapy 6999:bhs-52thiaz-ala-betapy 7000:bhs-me25oxaz-ala-zdap 107001:ibhs-25oxaz-bala-betabenfu 7002:phhis-24thiaz-bala-beta34dcph 7003:ibhs-24thiaz-bala-betadcphch 7004:ibhs-25thiaz-gly-betatrif 7005:ibhs-oxadiaz-gly-betahbcph 157006:bhs-nme35pyr-bala-betaimid 7007:bhs-oxadiaz-bala-betaamibe 7008:phhs-25oxaz-bala-betafu2 7009:tolhs-24thioph-gly-betahbcph 7010:2py-25fur-bala-betapy 207011:2py-25oxaz-bala-betainy) 7012:tolhs-me25thiaz-leu-betaph 7013:bhs-ithiadiaz-bala-betadmph 7014:bhs-nme35pyr-gly-busu2be 7015:bhs-me24thiaz-gly-betadcph 257016:tolhs-oxadiaz-bala-suabu 7017:bhs-24thioph-ala-beta34meoph 7018:tolhs-24thiaz-bala-betabnaphth 7019:ibhs-25methiaz-gly-zdapee 7020:tolhs-24thiaz-bala-betacbph 307021:bhs-25thiaz-bala-betahni 7022:ibhs-oxadiaz-bala-betaheph 7023:phhs-25thiaz-bala-betapbiph 7024:ibhs-25oxaz-gly-betafu3 7025;tolhs-24thioph-bala-betadcph 357026:2py-me25thiaz-bala-beta34meoph 7027:tolhs-ithiadiaz-gly-betaomebendi 7028:tolhs-24thiaz-bala-psdapch 7029; phhs-nme35pyr-bala-beta23meoph 7030: bhs-24thioph-gly-betadcphch 7031: phhs-nme35pyr-gly-betafph 7032: tolhs-24thioph-bala-betadcphtb 7033: bhs-nme35pyr-bala-betadmph 7034: bhs-oxadiaz-gly-betadcphtb 7035: phhs-ithiadiaz-gly-betapyr 7036: dhim-24thiaz-gly-betameph 7037: bgua-24thiaz-gly-betameph 107038: bhs-24thiaz-ala-betapy 7039: tolhs-24thiaz-bala-betaet 7040: ibhs-25thiaz-gly-betadbph 7041: 2py-26py-gly-betaanaphth 7042: bhs-25oxaz-bala-betadhbfu 157043: phhs-25oxaz-gly-betamethi 7044: bim-24im-gly-psdap 7045: tolhs-25oxaz-gly-betadhbfu 7046: gua-24oxaz-gly-betahb 7047: phhs-oxadiaz-bala-betaph 207048: ibhs-24thioph-bala-betaomebendi 7049: bhs-24thiaz-ala-beta3quin 7050: bhs-25oxaz-bala-beta34meoph 7051: ibhs-25methiaz-gly-beta4bph 7052: bhs-nme35pyr-bala-betapbiph 257053: phhs-25methiaz-bala-psdap 7054: bhs-25methiaz-bala-betahcbph 7055: bhs-oxadiaz-gly-betafu3 7056: phhs-oxadiaz-bala-betaanaphth 7057: 2py-42nmeim-gly-zdap 307058: bhs-53pyrazo-leu-betadcph 7059: ibhs-25oxaz-bala-betahcbph 7060: gua-24thiaz-gly-betaol 7061: ibhs-nme35pyr-bala-aspaba 7062: impy-42nmeim-gly-betathioph 357063: tolhs-24thioph-bala-betahph 7064: bhs-24thiaz-bala-betamesu 7065: phhs-nme35pyr-giy-betathio3 7066: 2py-24thioph-bala-betapy 7067: phhs-25thiaz-gly-betadcphch 7068: phhs-ithiadiaz-gly-betabdimo 7069: bim-me24thioph-ala-betadcph 7070: phhs-25methiaz-bala-zdaptb 7071: tolhs-25oxaz-gly-betafbph 7072: bgua-25thiaz-gly-betameph 7073: thazep-25thioph-gly-betadcph 7074: 2py-me24oxaz-gly-zdap 7075: tolhs-24thioph-gly-betadtrif 7076: tolhs-ithiadiaz-gly-betal3bendi 7077: bhs-me25thioph-bala-psdap 7078: ibhs-nme35pyr-bala-betampy 7079: phhs-25oxaz-gly-betahni 7080: tolhs-24thioph-gly-betambiph 7081: 2py-25thiaz-hphe-psdap 7082: tolhs-25oxaz-bala-zdapch 7083: tolhs-nme35pyr-bala-beta3quin 7084: ibhs-25oxaz-bala-betahmph 7085: phhs-nme35pyr-gly-betadcphtb 7086: bhs-nme35pyr-gly-betadmph 7087: phhs-25methiaz-gly-betadmph 7088: ibhs-nme35pyr-gly-beta3quin 7089: ibhs-24thiaz-bala-betaibph 7090: bhs-25oxaz-bala-busu2be 7091: dhim-42pym-gly-zdap 7092: tolhs-25methiaz-bala-betatos 7093: phhs-nme35pyr-gly-beta13bendi 7094: bhs-24thioph-gly-betabph 7095: tolhs-oxadiaz-Bata-betaphethioa 7096: ibhs-nme35pyr-gly-betathiome 7097: bhs-oxadiaz-bala-betamesu 7098: bhs-oxadiaz-gly-zdapee 7099: phhs-oxadiaz-gly-beta3quin 7100: ibhs-25methiaz-gly-betaipr 7101: ibhs-nme35pyr-bala-betaphethioa 7102: gua-24oxaz-gly-betaol 7103: tolhs-24thiaz-bala-betapyee 7104: bhs-ithiadiaz-nmgly-betacthioph 7105: phhs-oxadiaz-gly-betadcphtb 7106: tolhs-ithiadiaz-gly-betabnaphth 7107: ibhs-25oxaz-bala-betabmph 7108: bim-52thiaz-ala-psdap 7109: tolhs-25methiaz-gly-betamesu 7110: hyd-25oxaz-gly-betapy 7111: bhs-24thioph-bala-betapyee 7112:2py-26py-ala-betameph 7113: bim-25methiaz-gly-aspbzla 7114: ibhs-nme35pyr-gly-betadmph 7115: bim-25thiaz-bala-betadcph 7116: tolhs-24thioph-gly-betatrif 7117:phhs-24thiaz-giy-betamethioph 7118: tolhs-me24thiaz-ala-betadcph 7119: phhs-oxadiaz-gly-betadito 7120: tolhs-ithiadiaz-gly-beta34meoph 7121: bhs-ithiadiaz-gly-zdaptb 7122:impy-24thioph-bala-betah35dc 7123: ibhs-25oxaz-bala-betadbph 7124: 2py-25thioph-gly-betameph 7125: bim-25methiaz-bala-betahc 7126: tolhs-me24thioph-gly-betaph 7127:tolhs-oxadiaz-gly-betaftrif 7128: ibhs-oxadiaz-gly-betathiobe 7129: tolhs-nme35pyr-gly-beta35dbph 7130: ibhs-nme35pyr-bala-ibsdap 7131: phhs-25oxaz-gly-betahmph 7132:bhs-oxadiaz-ala-betadhbfu 7133: impy-25thiaz-bala-betamethi 7134: ibhs-nme35pyr-bala-psdapch 7135: bhs-me25oxaz-ala-psdap 7136: bhs-ithiadiaz-nmgly-betahph 7137:bhs-oxadiaz-ala-betacthioph 7138: dhim-26py-phe-zdap 7139: bhs-24thioph-bala-betah35dc WOOOlfififi18 PCTIEP001034fi9 7140:bhs-oxadiaz-bala-busu2be 7141:ibhs-25thiaz-gly-betaol 7142:bhs-oxadiaz-bala-betatbuph 7143:ibhs-nme35pyr-bala-betaipro 7144:bhs-me24thioph-leu-betaph 7145:ibhs-24thioph-gly-betampy 7146:phhs-oxadiaz-gly-psdap 7147:bhs-nme35pyr-gly-betamethioph 7148:bhs-25methiaz-baia-betathio3 7149:tolhs-24thiaz-bala-betainyl 7150:phhs-me25thioph-leu-beta34meoph 7151:2py-me25thiaz-leu-psdap 7152:bhs-ithiadiaz-bala-aspbzla 7153:thpy-42nmeim-gly-psdap 7154:phhs-24thioph-gly-betainyl 7155:phhs-25methiaz-gly-betambiph 7156:ibhs-nme35pyr-gly-suabu 7157:bhs-oxadiaz-gly-betameph 7158:impy-24thiaz-gly-beta34meoph 7159:ibhs-nme35pyr-bala-betatbuph 7160:ibhs-24thioph-gly-busu2be 7161:bhs-24thioph-gly-betamesu 7162:tolhs-ithiadiaz-gly-zdap 7163:gua-25thiaz-gly-betameph 7164:ibhs-nme35pyr-gly-betacthioph 7165:bhs-24im-leu-psdap 7166:ibhs-24thiaz-bala-betacbph 7167:bhs-oxadiaz-bala-betahni 7168:tolhs-24thiaz-gly-betapyee 7169:ibhs-24thioph-bala-betapyr 7170:phhs-nme35pyr-gly-beta34meoph 7171:bhs-24thiaz-ala-betadito 7172:bim-42nmeim-bala-betabthioph 7173:bhs-24thiaz-bala-betacbph 7174:ibhs-nme35pyr-bala-betabph 7175:phhs-ithiadiaz-gly-betahmph 7176:tolhs-ithiadiaz-bala-psdaptb 7177: ibhs-25oxaz-bala-betadmoph 7178: tolhs-me24oxaz-ala-zdap 7179: ibhs-ithiadiaz-bala-betahcbph 7180:, ibhs-25methiaz-bala-betathioph 7181: tolhs-25methiaz-gly-psdaptb 7182: tolhs-25oxaz-bala-betaph 7183: bhs-25thiaz-ala-betadmph 7184: bhs-24oxaz-bala-betadcph 7185: ibhs-24thioph-bala-psdapee 7186:bhs-ithiadiaz-gly-betapyr 7187: bhs-42nmeim-bala-betadito 7188: bim-24thiaz-bala-asppha 7189: bhs-24thiaz-gly-beta23meoph 7190: bhs-nme35pyr-nmgly-betacph 7191:bhs-24oxaz-leu-betapy 7192: impy-24thiaz-bala-betaphethioa 7193: phhs-ithiadiaz-gly-asppha 7194: phhs-25methiaz-gly-betapyr 7195: phhs-24thioph-gly-betaph 7196:dhim-26py-ala-psdap 7197: ibhs-24thioph-bala-betafu3 7198: ibhs-ithiadiaz-bala-betahb 7199: bhs-ithiadiaz-gly-betaomebendi 7200: phhs-25oxaz-bala-betabenfu 7201:tolhs-25thiaz-bala-betaipro 7202: phhs-25oxaz-bala-beta13bendi 7203: tolhs-oxadiaz-gly-betahc 7204: ibhs-25thiaz-bala-betadcphtb 7205: bhs-me24oxaz-bala-psdap 7206:ibhs-nme35pyr-bala-zdapee 7207: phhs-24thioph-bala-betainyl 7208: ibhs-24thioph-gly-zdap 7209: bhs-25methiaz-ala-betaanaphth 7210: tolhs-24thioph-gly-betapyee 7211:phhs-25thiaz-bala-ibsdap 7212: tolhs-24thiaz-gly-betabenfu 7213: bhs-oxadiaz-ala-beta23meoph W000166618 PCTlEP00103469 7214.bhs-25methiaz-ala-beta3quin 7215:phhs-25thiaz-gly-betaimid 7216:ibhs-nme35pyr-bala-beta34dcph 7217:ibhs-oxadiaz-gly-betahcbph 7218:ibhs-nme35pyr-gly-aspbzla 7219:2py-25oxaz-a.la-betapy 7220:gua-24thiaz-gly-betahdbph 7221:phhs-nme35pyr-bala-betaph 7222:bhs-nme35pyr-bala-betahdbph 107223:bhs-24thiaz-gly-betafph 7224:tolhs-25thiaz-bala-zdapch 7225:ibhs-24thiaz-gly-betapy 7226:tolhs-nme35pyr-bala-betadito 7227:phhs-25thiaz-bala-betafluo 157228:tolhs-24thiaz-gly-betaimid 7229:bhs-oxadiaz-gly-betafphe 7230:tolhs-me24thiaz-giy-betaph 7231:bim-53pyrazo-leu-psdap 7232:thazep-26py-gly-betainyl 207233:tolhs-nme35pyr-bala-betafluo 7234:tolhs-25methiaz-bala-betal3bendi 7235:bhs-25thioph-bala-psdap 7236:2pmhs-24thiaz-gly-betathiome 7237:2py-25oxaz-gly-betabthioph 257238:bhs-25thiaz-bala-betaoxope 7239:bhs-25oxaz-gly-betapych 7240:ibhs-25oxaz-gly-betahmph 7241:bhs-25oxaz-gly-betaet 7242:gua-26py-gly-betainyl 307243:bim-53pyrazo-gly-betadcph 7244:2py-25oxaz-bala-aspaba 7245:bhs-me25thioph-bala-betadcph 7246:ibhs-25methiaz-bala-betabpy 7247:bhs-24oxaz-gly-psdap 357248:bhs-25thiaz-bala-zdapch 7249:tolhs-24thiaz-bala-betaimid 7250:ibhs-24thioph-gly-beta34meoph W000166618 PCTlEP00103469 7251:tolhs-25methiaz-bala-betaipr 7252:bhs-nme35pyr-bala-betadcphee 7253:tolhs-oxadiaz-gly-betabph 7254:gua-24thiaz-gly-betaheph 7255:tolhs-nme35pyr-gly-zdaptb 7256:ibhs-25oxaz-bala-betahmo 7257:bim-me25oxaz-leu-beta34meoph 7258:2 py-24 i m-al a-beta py 7259:bhs-24thiaz-nmgly-betainyl 107260:phhs-25thiaz-bala-betaipr 7261:bhs-24thiaz-gly-asppha 7262:2py-53pyrazo-leu-betadcph 7263:bhs-me24thioph-bala-betadcph 7264:dhim-26py-gly-betameph 157265:bhs-nme35pyr-ala-betamesu 7266:ibhs-25oxaz-gly-betabpy 7267:bhs-thiadiaz-gly-psdap 7268:bim-25methiaz-leu-zdap 7269:phhs-24thiaz-bala-betabnaphth 207270:ibhs-nme35pyr-gly-betadmoph 7271:2py-25th iaz-bala-betaheph 7272:dhpyrr-24thioph-gly-betapy 7273:phhs-me24thiaz-gly-betadcph 7274:tolhs-24thioph-gly-betahc 257275:bhs-24thiaz-gly-betahdbph 7276:bim-25oxaz-gly-betaph 7277:bim-nme35pyr-bala-aspbzla 7278:tolhs-nme35pyr-gly-zdap 7279:bhs-25methiaz-bala-psdapee 307280:2py-me24thiaz-leu-betapy 7281:bhs-oxadiaz-nmgly-beta3quin 7282:tolhs-24thiaz-gly-betahph 7283:bhs-25thiaz-phg-betameph 7284:tolhs-me25oxaz-leu-betapy 357285:2py-24thioph-bala-betafluo 7286:tolhs-25oxaz-bala-betaheph 7287:ibhs-25thiaz-bala-betabenfu 7288:phhs-nme35pyr-gly-ibsdap 7289:ibhs-24thioph-bala-betamethi 7290:ibhs-24thioph-bala-betaphethio 7291:ibhs-24thioph-gly-suabu 7292:bhs-25methiaz-bala-betabph 7293:2py-25methiaz-bala-betabnaphth 7294:tolhs-24thioph-bala-betahni 7295:bhs-nme35pyr-gly-betainyl 7296:ibhs-25methiaz-gly-betadito 7297:impy-25methiaz-gly-betacbph 7298:ibhs-oxadiaz-giy-betafphe 7299:bhs-oxadiaz-gly-betambiph 7300:bhs-nme35pyr-ala-betathio3 7301:bhs-25methiaz-gly-betapytb 7302:2py-25oxaz-bala-zdap 7303:phhs-24thiaz-gly-betahmo 7304:bim-24thioph-ala-psdap 7305:bim-me24oxaz-ala-betadcph 7306:bhs-24thioph-gly-betafu2 7307:ibhs-25thiaz-gly-betapytb 7308:ibhs-24thioph-bala-betameph 7309:phhs-oxadiaz-gly-betafu3 7310:ibhs-25thiaz-gly-betambiph 7311:ibhs-oxadiaz-gly-betathioph 7312:phhs-25methiaz-bala-betahbcph 7313:bim-24thiaz-gly-zdap 7314:bhs-25fur-baia-betadcph 7315:tolhs-oxadiaz-bala-betatrif 7316:bhs-24im-bala-betadcph 7317:tolhs-25methiaz-bala-zdap 7318:phhs-ithiadiaz-gly-betadcphee 7319:ibhs-25methiaz-bala-betaftrif 7320:tolhs-nme35pyr-gly-betapy 7321:phhs-25methiaz-gly-betabmph 7322:dhthi-42nmeim-baia-psdap 7323:tolhs-24thiaz-bala-beta34dcph 7324:tolhs-me25thiaz-leu-zdap WOOOI66618 PCTlEP00103469 7325:2py-me25thiaz-bala-betaph 7326:bhs-25methiaz-ala-zdap 7327:bhs-24thioph-nmgly-betadmph 7328:bhs-24thiaz-leu-zdap 7329:ibhs-24thiaz-bala-betabdimo 7330:tolhs-25oxaz-gly-psdaptb 7331:phhs-me24thioph-ala-beta34meoph 7332:bim-25thiaz-phg-zdap 7333:ibhs-24thiaz-gly-betapym 7334:bim-me25thiaz-ala-betapy 7335:2py-42oxaz-bala-betapy 7336:bim-42oxaz-gly-betapy 7337:bhs-25oxaz-gly-betapytb 7338:bhs-25oxaz-gly-betapyee 7339:gua-42pym-gly-betabdimo 7340:bhs-26py-gly-betameph 7341:impy-26py-gly-psdap 7342:bhs-25oxaz-bala-betabediox 7343:tolhs-oxadiaz-bala-zdapee 7344:bhs-nme35pyr-gly-betathiobe 7345:tolhs-25methiaz-gly-betaomebendi 7346:ibhs-24thioph-bala-betampy 7347:ibhs-24thiaz-bala-betapbiph 7348:ibhs-24thioph-bala-psdapch 7349:phhs-24thiaz-bala-betaet 7350:bhs-25methiaz-bala-betaoxaz 7351:bhs-me24thioph-leu-betadcph 7352:2py-25thioph-bala-betadcph 7353:tolhs-ithiadiaz-gly-betathiobe 7354:bhs-25methiaz-bala-betathiome 7355:bhs-oxadiaz-gly-betaoxope 7356:bhs-24thiaz-bala-betabnaphth 7357:phhs-nme35pyr-bala-betahph 7358:ibhs-25thiaz-gly-zdaptb 7359:bhs-oxadiaz-ala-betahph 7360:ibhs-42nmeim-gIy-betameph 7361:ibhs-24thioph-bala-betaol 7362:tolhs-24thioph-bala-betah35dc 7363:ibhs-24thiaz-gly-betadcphtb 7364:bhs-25thiaz-gly-betabenfu 7365:tolhs-ithiadiaz-bala-betaoxope 7366:ibhs-oxadiaz-gly-betaheph 7367:bhs-24thiaz-ala-betacthioph 7368:ibhs-24thioph-gly-betapbiph 7369:bhs-oxadiaz-nmgly-betathio3 7370:bim-me25thiaz-ala-betaph 7371:ibhs-oxadiaz-gly-betahph 7372:gua-42pym-gly-betampy 7373:tolhs-25oxaz-gly-betafu2 7374:phhs-nme35pyr-bala-betaoxope 7375:ibhs-nme35pyr-bala-betaimid 7376:bhs-25oxaz-gly-psdapee 7377:bhs-25thiaz-nmgly-betacph 7378:tolhs-24thioph-bala-aspbzla 7379:ibhs-25methiaz-gly-psdapee 7380:tolhs-25thiaz-gly-betafph 7381:phhs-ithiadiaz-gly-betaphethio 7382:ibhs-ithiadiaz-bala-betafu3 7383:ibhs-25oxaz-bala-betadcphee 7384:phhs-25methiaz-gly-betaanaphth 7385:phhs-ithiadiaz-gly-zdapee 7386:bim-ithiadiaz-gly-aspibua 7387:phhs-25oxaz-bala-betaheph 7388:tolhs-25methiaz-gly-zdaptb 7389:bhs-oxadiaz-ala-betainyl 7390:tolhs-24thioph-gly-ibsdap 7391:2py-nme35pyr-gly-zdap 7392:bim-24thiaz-bala-betahc 7393:2py-me25thioph-bala-zdap 7394:imhs-25oxaz-bala-psdap 7395:bhs-24thioph-bala-betahni 7396:tolhs-24thioph-gly-betaet 7397:ibhs-25thiaz-gly-betahdbph 7398:phhs-nme35pyr-gly-psdapee W0001666'18 PCTIEP00103469 7399:phhs-oxadiaz-gly-betahbcph 7400;hyd-24thioph-bala-betameph 7401:phhs-25thiaz-bala-busu2be 7402:tolhs-24thioph-gly-betahph 7403:2py-24thioph-bala-betaheph 7404:tolhs-nme35pyr-bala-beta13bendi 7405:bhs-ithiadiaz-gly-betahb 7406:bhs-oxadiaz-bala-betaibph 7407:ibhs-25methiaz-gly-betafphe 7408:phhs-24thiaz-gly-betahph 7409:2py-24thioph-leu-psdap 7410:phhs-nme35pyr-bala-betadcphtb 7411:ibhs-24thiaz-gly-betadcphch 7412:2py-24thiophme-ala-betapy 7413:bhs-24thioph-bala-psdaptb 7414:ibhs-25methiaz-bala-betabenfu 7415:2py-ithiadiaz-leu-betapy 7416:bim-42nmeim-leu-psdap 7417:gua-42pym-gly-betahmph 7418:phhs-25methiaz-gly-betabpy 7419:tolhs-24thioph-gly-betaamibe 7420:bhs-25oxaz-bala-psdapee 7421:2pmhs-25methiaz-bala-betamethioph 7422:dimethpym-24thiaz-gly-betahdcph 7423:bhs-24thiaz-bala-betah35dc 7424:tolhs-24thioph-bala-betabenfu 7425:bim-24thioph-ala-betadcph 7426:phhs-25methiaz-bala-betamesu 7427:bhs-nme35pyr-bala-betathiobe 7428:phhs-ithiadiaz-gly-zdap 7429:phhs-ithiadiaz-bala-betameph 7430:tolhs-nme35pyr-bala-betambiph 7431:bhs-35fur-leu-betapy 7432:phhs-25thiaz-gly-betaanaphth 7433:bhs-me24thiaz-gly-betaph 7434:bhs-25methiaz-bala-betameph 7435:ibhs-nme35pyr-bala-psdaptb 7436:phhs-me24thioph-bala-beta34meoph 7437:bhs-25thiaz-gly-betaomebendi 7438:bhs-25thiaz-gly-betadbph 7439:bhs-25methiaz-gly-betamethi 7440:gua-24oxaz-gly-betaet 7441:phhs-24thioph-gly-suabu 7442:bhs-42nmeim-bala-beta35dbph 7443:ibhs-25thiaz-gly-betahmo 7444:bhs-24thiaz-gly-zdapee 107445:ibhs-24thiaz-bala-betahdbph 7446:ibhs-24thioph-gly-betahb 7447:bim-25oxaz-gly-betadtrif 7448:bhs-24thioph-ala-betahph 7449:bhs-25oxaz-leu-psdap 157450:bhs-nme35pyr-bala-betainyl 7451:bhs-ithiadiaz-ala-beta3quin 7452:phhs-24thiaz-bala-betahdcph 7453:bim-me25thiaz-leu-betapy 7454:2py-25thiaz-gly-betainyl 207455:tolhs-25oxaz-gly-beta13bendi 7456:tolhs-24thiaz-bala-beta4bph 7457:tolhs-ithiadiaz-bala-betampy 7458:bhs-25oxaz-gly-betafphe 7459:tolhs-ithiadiaz-bala-betahmph 257460:ibhs-25thiaz-gly-betaphethioa 7461:ibhs-24thioph-bala-betacph 7462:bhs-25methiaz-bala-betaamibe 7463:phhs-me25thioph-leu-psdap 7464:2py-me25thiaz-leu-beta34meoph 307465:ibhs-ithiadiaz-bala-betaamibe 7466:phhs-oxadiaz-bala-betaoxaz 7467:phhs-nme35pyr-gly-betaphethioa 7468:bhs-24thiaz-gly-betabpy 7469:tolhs-ithiadiaz-bala-betamethioph 357470.bim-24oxaz-leu-psdap 7471:bhs-thiadiaz-leu-psdap 7472:2py-oxadiaz-gly-aspaba W~00166618 PCTlEP00I03469 7473:2py-42nmeim-gly-psdap 7474:impy-25methiaz-gly-betathiobe 7475:tolhs-25oxaz-bala-betampy 7476:ibhs-25oxaz-bala-aspbzla 7477:ibhs-25thiaz-bala-betaamibe 7478:phhs-24thioph-gly-betabmph 7479:ibhs-25thiaz-bala-betaet 7480:ibhs-25methiaz-bala-betaoxope 7481:bhs-nme35pyr-bala-betaibph 107482:tolhs-25oxaz-gly-betapbiph 7483:2py-25methiaz-bala-suabu 7484:tolhs-ithiadiaz-gly-betadcph 7485:2pmhs-42nmeim-gly-betaoxaz 7486:ibhs-25methiaz-bala-psdaptb 157487:bhs-25methiaz-bala-betaomebendi 7488:impy-25oxaz-gly-beta23meoph 7489:bhs-nme35pyr-gly-psdaptb 7490:bhs-24thioph-gly-betacph 7491:bhs-25oxaz-bala-aspibua 207492:tolhs-nme35pyr-bala-zdapee 7493:bhs-25methiaz-bala-betamesu 7494:2py-42oxaz-leu-betadcph 7495:ibhs-25thiaz-gly-betadmoph 7496:bhs-nme35pyr-bala-betaipro 257497:bim-42nmeim-gly-betainyl 7498:phhs-nme35pyr-gly-betaph 7499:tolhs-25methiaz-bala-betafph 7500:tolhs-24thioph-bala-psdap 7501:bhs-25thioph-ala-betameph 307502:tolhs-25oxaz-bala-betaoxaz 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7781:2py-24thiaz-gly-psdap 7782:tolhs-24thiaz-gly-betathiome 157783:bhs-ithiadiaz-nmgly-betaoxaz 7784:thazep-24oxaz-gly-betapy 7785:phhs-oxadiaz-bala-psdap 7786:ibhs-25oxaz-gly-beta4bph 7787:phhs-25thiaz-gly-betapyee 207788:bhs-35thioph-gly-betapy 7789:2py-35fur-1 eu-psdap 7790:tolhs-24thioph-gly-aspibua 7791:tolhs-24thioph-bala-betaftrif 7792:bhs-25methiaz-gly-betahc 257793:tolhs-24thiaz-gly-psdapee 7794:bim-24thiaz-gly-betapy 7795:tolhs-25thiaz-bala-betaibph 7796:tolhs-me24thiaz-leu-betadcph 7797:2py-me24oxaz-bala-beta34meoph 307798:bhs-nme35pyr-nmgly-beta13bendi 7799:phhs-25oxaz-gly-betafphe 7800:bhs-nme35pyr-bala-betahph 7801.impy-25thiaz-gly-zdap 7802:gua-24oxaz-giy-betafluo 357803:phhs-ithiadiaz-gly-betaheph 7804.bhs-42nmeim-leu-betadcph 7805:phhs-nme35pyr-bala-busu2be 7806: bim-thiadiaz-leu-psdap 7807: dhim-52thiaz-ala-zdap 7808: bhs-24thioph-gly-betahdbph 7809: nmhs-24oxaz-gly-betapy 7810: gua-42pym-gly-betahb 7811: tolhs-ithiadiaz-gly-betathiome 7812: 2py-24thioph-bala-aspbzla 7813: bhs-25oxaz-gly-betathiobe 7814: tolhs-me24oxaz-bala-psdap 7815:bhs-24thioph-gly-betahmph 7816: tolhs-nme35pyr-bala-csdap 7817: ibhs-25thiaz-giy-betamesu 7818: phhs-24thiaz-bala-ibsdap 7819: 2py-thiadiaz-gly-betadcph 7820:2py-42oxaz-ala-betapy 7821: bhs-25thiaz-gly-psdapee 7822: bim-oxadiaz-ala-betadcph 7823: phhs-24thioph-bala-betadcphtb 7824: tolhs-25thiaz-gly-betampy 7825:ibhs-24thiaz-gly-betapych 7826: phhs-24thioph-gly-betamesu 7827: tolhs-me25thiaz-bala-psdap 7828: bim-25oxaz-bala-betadcph 7829: bhs-nme35pyr-gly-zdapch 7830:ibhs-25methiaz-gly-betaphethioa 7831: phhs-24thiaz-bala-aspaba 7832: tolhs-24thioph-bala-betahdbph 7833: bhs-me24thioph-leu-psdap 7834: phhs-25oxaz-gly-betathio3 7835:bhs-24thiaz-bala-beta4bph 7836: phhs-nme35pyr-gly-betatos 7837: ibhs-nme35pyr-bala-betaoxaz 7838: tolhs-24thioph-bala-betahbcph 7839: bhs-oxadiaz-gly-betahni 7840:phhs-25oxaz-bala-betaphethioa 7841: 2py-24thioph-bala-asppha 7842: tolhs-24thioph-gly-betaomebendi W000166698 PCTlEP00103469 7843: tolhs-25oxaz-bala-betabediox 7844: impy-24thioph-bala-betamesu 7845: ibhs-24thiaz-bala-betathiome 7846: 2py-4.2nmeim-ala-betapy 7847: ibhs-24thiaz-bala-betaphethio 7848: phhs-24thioph-bala-betafbph 7849: phhs-me25thioph-ala-psdap 7850: bhs-nme35pyr-gly-betamethi 7851: bim-me25thivph-bala-beta34meoph 107852: bhs-24thioph-gly-betapyr 7853: ibhs-oxadiaz-gly-betaoxaz 7854: bhs-me24thioph-gly-betaph 7855: bhs-53pyrazo-ala-psdap 7856: phhs-oxadiaz-bala-betabdimo 157857: bhs-24thiaz-gly-betadtrif 7858: bim-25oxaz-leu-betadcph 7859: ibhs-ithiadiaz-gly-betapym 7860: bhs-nme35pyr-bala-beta3quin 7861: bhs-ithiadiaz-bala-betabdimo 207862: ibhs-oxadiaz-bala-betahmph 7863: tolhs-25methiaz-gly-betahmo 7864: ibhs-25methiaz-gly-betamethi 7865: ibhs-25thiaz-gly-aspaba 7866: bhs-oxadiaz-bala-betadcphch 257867: ibhs-ithiadiaz-bala-betapych 7868: bhs-24thiaz-gly-betabmph 7869: ibhs-ithiadiaz-gly-csdap 7870: bhs-25oxaz-ala-betameph 7871: bhs-25oxaz-gly-psdapch 307872: bhs-25thiaz-bala-beta35dbph 7873: bim-nme35pyr-bala-betadcph 7874: phhs-oxadiaz-bala-betadcph 7875: bim-24oxaz-leu-zdap 7876: bhs-ithiadiaz-gly-betaphethioa 357877: bhs-24thiaz-gly-betatho3 7878: tolhs-24thiaz-bala-betampy 7879: bhs-24thiaz-gly-betadito W000166618 PCTlEP00/03469 7880: bhs-me24thioph-bala-betaph 7881: 2py-24oxaz-ala-betainyl 7882: bhs-nme35pyr-bala-betabthioph 7883: phhs-25methiaz-bala-betathio3 7884: bhs-25thiaz-gly-betabph 7885: tolhs-25thiaz-gly-betadcph 7886: ibhs-24thioph-gly-betaimid 7887: ibhs-24thiaz-gly-betadcph 7888: ibhs-ithiadiaz-gly-psdapch 7889:tolhs-me25thiaz-ala-betaph 7890: thazep-42pym-gly-betadcph 7891: bhs-25thiaz-bala-betaol 7892: phhs-ithiadiaz-gly-psdapee 7893: bhs-24thioph-ala-betaipro 7894:bhs-24thioph-gly-betaftrif 7895: bhs-ithiadiaz-bala-betapych 7896: phhs-24thiaz-gly-betaamibe 7897: bhs-nme35pyr-giy-betaphethioa 7898: bim-25methiaz-gly-betaanaphth 7899:bim-thiadiaz-gly-zdap 7900: ibhs-25methiaz-gly-asppha 7901: tolhs-24thiaz-bala-betaphethio 7902: ibhs-24thiaz-bala-psdapch 7903: tolhs-25thiaz-gly-betaanaphth 7904:bhs-25methiaz-bala-betadcphee 7905: tolhs-me24oxaz-bala-betadcph 7906: bhs-25methiaz-bala-psdap 7907: tolhs-nme35pyr-bala-betafph 7908: ibhs-oxadiaz-gly-zdaptb 7909:bhs-oxadiaz-ala-betabpy 7910: bhs-nme35pyr-gly-betathiome 7911: 2py-42oxaz-gly-psdap 7912: bim-me24oxaz-gly-betapy 7913: tolhs-25oxaz-bala-betahb 7914:ibhs-ithiadiaz-gly-betah35dc 7915: phhs-25methiaz-bala-betapym 7916: bhs-ithiadiaz-gly-busu2be 7917:tolhs-ithiadiaz-bala-betacph 7918:tolhs-24thioph-bala-zdapee 7919:bhs-me25thiaz-leu-psdap 7920:gua-24thiaz-gly-betabnaphth 7921:bhs-oxadiaz-gly-betaipr 7922:bhs-me25thiaz-bala-beta34meoph 7923:bhs-25thiaz-bala-betamethioph 7924:tolhs-24thiaz-bala-betadito 7925:ibhs-ithiadiaz-bala-betacbph 7926:phhs-24thiaz-gly-betafbph 7927:phhs-24thioph-gly-betacph 7928:phhs-25methiaz-bala-betainyl 7929:ibhs-nme35pyr-gly-betabthioph 7930:tolhs-24thiaz-bala-betahph 7931:tolhs-25oxaz-gly-betahcbph 7932:tolhs-me24oxaz-bala-beta34meoph 7933:tolhs-me25oxaz-leu-betaph 7934:bhs-nme35pyr-gly-betafu2 7935:bhs-me25oxaz-gly-beta34meoph 7936:tolhs-25thiaz-bala-betapyee 7937:ibhs-nme35pyr-bala-betaanaphth 7938:bhs-oxadiaz-ala-betathio3 7939:2py-25fur-ala-betapy 7940:tolhs-25oxaz-bala-csdap 7941:tolhs-nme35pyr-bala-aspibua 7942:4pmhs-25methiaz-bala-betameph 7943:bhs-nme35pyr-ala-betabnaphth 7944:phhs-24thiaz-gly-betabmph 7945:tolhs-24thiaz-gly-betaoxaz 7946:ibhs-ithiadiaz-bala-betambiph 7947:impy-25methiaz-bala-betah35dc 7948:tolhs-25oxaz-gly-betaet 7949:phhs-oxadiaz-bafa-betampy 7950:phhs-ithiadiaz-gly-betambiph 7951:bhs-nme35pyr-gly-betapytb 7952:phhs-ithiadiaz-bala-betabpy 7953:bim-25thioph-leu-zdap 7954:bhs-24thiaz-ala-betafphe 7955:ibhs-nme35pyr-bala-betafu2 7956:bhs-24thiaz-bala-zdapee 7957:phhs-24thiaz-bala-betacthioph 7958:bim-53pyrazo-leu-zdap 7959:ibhs-24thiaz-bala-zdapee 7960:bim-me25thioph-gly-zdap 7961:ibhs-oxadiaz-bala-betacthioph 7962:tolhs-me25thioph-bala-psdap 7963:phhs-25thiaz-gly-betafu3 7964:ibhs-24thiaz-bala-betabenfu 7965:tolhs-25thiaz-gly-betacbph 7966:bhs-24thiaz-gly-betafbph 7967:bim-35fur-leu-betadcph 7968:bim-25oxaz-bala-betahph 7969:phhs-24thiaz-gly-beta34dcph 7970:ibhs-nme35pyr-gly-beta23meoph 7971:phhs-24thiaz-bala-betamethioph 7972:ibhs-25thiaz-gly-beta3quin 7973:bim-25thioph-leu-psdap 7974:bhs-25thiaz-gly-psdaptb 7975:bhs-ithiadiaz-bala-betambiph 7976:bhs-24thiaz-bala-betabthioph 7977:bhs-24thiaz-gly-beta34meoph 7978:bhs-24thioph-bala-betambiph 7979:bhs-ithiadiaz-ala-psdap 7980:phhs-25thiaz-gly-betapych .7981:bhs-oxadiaz-bala-betaph 7982:2py-42oxaz-bala-zdap 7983:bhs-oxadiaz-gly-betadcphch 7984:bhs-25thiaz-gly-betabmph 7985:bhs-25methiaz-gly-betafu3 7986:bhs-nme35pyr-gly-betahmofu 7987:ibhs-oxadiaz-bala-psdap 7988:2py-me24thioph-ala-beta34meoph 7989:2py-nme35pyr-bala-betadcph 7990:phhs-24thioph-bala-betathio3 VIIOOOl66618 PCTIEP00103469 7991: 2py-35th ioph-ala-betadcph 7992: phhs-24thioph-gly-betahcbph 7993: 2py-35fur-leu-betadcph 7994: ibhs-oxadiaz-bala-betadmph 7995. bhs-nme35pyr-gly-betaph 7996: ibhs-oxadiaz-bala-betapytb 7997: phhs-25thiaz-gly-zdap 7998: impy-25oxaz-gly-betahdbph 7999: bhs-me25oxaz-bala-betadcph 8000:bim-25fur-gly-zdap 8001: bhs-25oxaz-ala-betaipro 8002: bhs-24thioph-nmgly-betahmph 8003: tolhs-nme35pyr-gly-betamethi 8004: bhs-me25thiaz-ala-psdap 8005:gua-24thiaz-gly-betaphethioa 8006: bim-25methiaz-leu-betadcph 8007: ibhs-ithiadiaz-bala-csdap 8008: phhs-25oxaz-gly-aspaba 8009: tolhs-oxadiaz-gly-betathiome 8010:phhs-24thioph-gly-psdapee 8011: phhs-nme35pyr-gly-psdap 8012; bhs-25oxaz-nmgly-betameph 8013: tolhs-oxadiaz-gly-beta23meoph 8014: ibhs-24thiaz-bala-betathioph 8015:tolhs-24thiaz-gly-betaet 8016: bhs-25oxaz-ala-betacthioph 8017: tolhs-oxadiaz-gly-betahmofu 8018: phhs-24thioph-gly-betaet 8019: ibhs-25thiaz-bala-betabph 8020:tolhs-24thioph-bala-betampy 8021: bhs-25oxaz-gly-betahni 8022: bhs-25oxaz-gly-betahmofu 8023: bhs-me25thiaz-ala-betadcph 8024: pbhs-24thioph-bala-beta35dbph 8025:dhim-42pym-ala-psdap 8026: 2py-24thioph-gly-betatbuph 8027: bhs-oxadiaz-ala-betadcph 8028: 2py-35thioph-leu-zdap 8029: phhs-oxadiaz-gly-betaimid 8030: phhs-nme35pyr-gly-betacph 8031: ibhs-nme35pyr-bala-zdap 8032: gua-26py-gly-betadmph 8033: phhs-25thiaz-gly-betaoxope 8034: ibhs-oxadiaz-gly-betaamibe 8035: phhs-24thioph-gly-betapyee 8036: 2py-35thioph-gly-betapy 8037:bhs-35fur-ala-betapy 8038: bhs-24thiaz-nmgly-betamesu 8039: phhs-nme35pyr-gly-betaanaphth 8040: bgua-42pym-gly-betainyl 8041: ibhs-24thiaz-bala-betafphe 8042:bhs-25thiaz-ala-betathio3 8043: tolhs-24thiaz-bala-betacthioph 8044: bhs-25fur-leu-betapy 8045: phhs-24thiaz-gly-betafu3 8046: phhs-24thiaz-gly-betahdcph 8047:tolhs-25thiaz-gly-aspibua 8048: phhs-25oxaz-bala-betapyee 8049: ibhs-oxadiaz-gly-aspaba 8050: phhs-25methiaz-bala-betafbph 8051: bhs-25oxaz-nmgly-betadito 8052:bhs-oxadiaz-bala-betapyee 8053: agua-25oxaz-bala-betameph 8054: bim-me25thioph-bala-betadcph 8055: tolhs-24thiaz-bala-betahb 8056: tolhs-me24thiaz-gly-psdap 8057:bhs-24thiaz-bala-betaphethioa 8058: 2py-25thiaz-leu-zdap 8059: ibhs-oxadiaz-gly-betah35dc 8060: tolhs-24thiaz-gly-beta4bph 8061: bhs-25methiaz-gly-betaipr 8062:tolhs-ithiadiaz-gly-betaibph 8063: dhim-23thioph-gly-betameph 8064: bhs-24thioph-bala-zdaptb 8065:ibhs-25oxaz-gly-betaibph 8066:bhs-oxadiaz-nmgly-betacthioph 8067:bim-me25thioph-gly-betapy 8068:bhs-24thioph-gly-betahbcph 8069:bim-me24oxaz-gly-betaph 8070:impy-25oxaz-bala-betahmo 8071:ibhs-25methiaz-gly-beta23meoph 8072:2py-ithiadiaz-bala-psdap 8073:phhs-24thiaz-gly-betatos 8074:bim-me24oxaz-leu-betaph 8075:2py-26py-gly-psdap 8076:bhs-24thiaz-ala-betathio3 8077:bhs-25thiaz-bala-betatrif 8078:bim-24thiaz-gly-aspibua 8079:phhs-oxadiaz-bala-betathiome 8080:tolhs-24thioph-gly-betaibph 8081:phhs-24thiaz-bala-betaphethio 8082:tolhs-ithiadiaz-bala-betaph 8083:bhs-24thiaz-bala-betathiome 8084:bhs-me25thioph-gly-zdap 8085:phhs-nme35pyr-gly-betathiome 8086:tolhs-ithiadiaz-gly-zdapee 8087:phhs-25oxaz-bala-betaamibe 8088:bim-24oxaz-bala-psdap 8089:phhs-25oxaz-bala-aspbzla 8090:bim-42oxaz-gly-zdap 8092:ibhs-25thiaz-bala-betatos 8092:ibhs-oxadiaz-bala-aspaba 8093:phhs-nme35pyr-gly-betadcph 8094:gua-24thiaz-gly-beta3quin 8095:2py-25oxaz-gly-betathiobe 8096:tolhs-25methiaz-bala-betabnaphth 8097:bhs-25oxaz-ala-betacph 8098:bhs-nme35pyr-bala-betahcbph 8099:bim-me24thioph-ala-betaph 8100:ibhs-25methiaz-bala-ibsdap 8101:bhs-25methiaz-leu-zdap 8102:bhs-25thiaz-ala-betadhbfu 8103:bim-42oxaz-gly-psdap 8104:bhs-25thiaz-gly-betabiph 8105:gua-25thioph-gly-betaipr 8106:phhs-24thioph-gly-betapych 8107:bhs-25oxaz-gly-beta23meoph 8108:tolhs-24thioph-bala-asppha 8109:bhs-24thiaz-gly-betaipro 8110:tolhs-ithiadiaz-bala-betahdcph 8111:bim-24thiaz-ala-zdap 8112:tolhs-25thiaz-bala-beta34meoph 8113:bhs-ithiadiaz-gly-betaipro 8114:tolhs-25thiaz-gly-betapych 8115:tolhs-24thioph-bala-aspibua 8116:bhs-nme35pyr-gly-betafbph 8117:dhim-52thiaz-ala-betadcph 8118:2py-35fur-ala-betadcph 8119:phhs-25thiaz-bala-zdap 8120:2pmhs-25thiaz-gly-betahbcph 8121:bhs-25thiaz-bala-betahph 8122:bhs-oxadiaz-bala-betathiobe 8123:bhs-25methiaz-ala-betathioph 8124:tolhs-25oxaz-gly-aspaba 8125:2py-24thiaz-g ly-beta35d bph 8126:ibhs-ithiadiaz-gly-betahc 8127:bhs-oxadiaz-bala-betabdimo 8128.phhs-25oxaz-bala-betaphethio 8129:bhs-25oxaz-ala-beta13bendi 8130:phhs-ithiadiaz-bala-beta23meoph 8131:bhs-25methiaz-gly-betafph 8132:tolhs-24thiaz-gly-betaol 8133:tolhs-oxadiaz-gly-betaipro 8134:tolhs-25methiaz-gly-aspbzla 8135:ibhs-oxadiaz-gly-betaanaphth 8136:tolhs-oxadiaz-bala-betaoxope 8137:bhs-25methiaz-nmgly-betacthioph 8138:2pmhs-25thiaz-gly-betaph W000166618 PCTlEP00l03469 8139:bhs-25oxaz-gly-betadcphch 8140:bim-25oxaz-bala-betabmph 8141:bhs-nme35pyr-gly-betafphe 8142:bhs-ithiadiaz-bala-betatos 8143:phhs-24thiaz-gly-betamethi 8144:thpym-24oxaz-gly-zdap 8145:tolhs-me25thiaz-bala-beta34meoph 8146:tolhs-nme35pyr-bala-betaimid 8147:bhs-nme35pyr-ala-betainyl 8148:bhs-25oxaz-gly-betatbuph 8149:2py-42pym-ala-betadcph 8150:tolhs-24thioph-gly-betafph 8151:bim-me25oxaz-bala-betapy 8152:bim-25methiaz-bala-aspbzla 8153:2py-me25thiaz-ala-zdap 8154:tolhs-25thiaz-gly-psdaptb 8155:2py-52thiaz-ala-betadcph 8156:bhs-25oxaz-bala-betah35dc 8157:gua-24oxaz-gly-betaipro 8158:tolhs-me25thioph-ala-psdap 8159:gua-24thiaz-gly-betamethi 8160:bhs-nme35pyr-leu-betadcph 8161:bim-oxadiaz-gly-betapy 8162:bhs-35fur-ala-psdap 8163:bhs-25methiaz-gly-betapy 8164:ibhs-24thiaz-bala-beta13bendi 8165:tolhs-24thiaz-bala-beta3quin 8166:bhs-ithiadiaz-bala-betatrif 8167:bhs-ithiadiaz-gly-betahmph 8168:tolhs-ithiadiaz-gly-betaheph 8169:tolhs-24thioph-gly-betampy 8170:tolhs-25oxaz-gly-betathiome 8171:ibhs-nme35pyr-gly-betahdcph 8172:ibhs-oxadiaz-bala-betabediox 8173:phhs-25methiaz-bala-betadhbfu 8174:bhs-25methiaz-gly-betabnaphth 8175:bhs-ithiadiaz-bala-betacph 8176:bhs-24thioph-bala-betadmph 8177:tolhs-nme35pyr-bala-betafu3 8178:phhs-25methiaz-gly-betahni 8179:ibhs-25methiaz-bala-betaphethioa 8180:tolhs-nme35pyr-bala-betamethioph 8181:tolhs-ithiadiaz-bala-betaphethio 8182:tolhs-25methiaz-gly-betaipro 8183:ibhs-24thiaz-gly-betaanaphth 8184:bhs-nme35pyr-bala-betabediox 8185:2pmhs-42nmeim-bala-betapym 8186:ibhs-25oxaz-gly-betaipro 8187:phhs-24thioph-gly-psdap 8188:bhs-25oxaz-nmgly-betathio3 8189:bhs-24thioph-bala-betadtrif 8190:tolhs-ithiadiaz-bala-betamethi 8191:tolhs-25methiaz-bala-betabenfu 8192:ibhs-24thioph-bala-betadmoph 8193:tolhs-25oxaz-gly-betahb 8194:tolhs-me24thiaz-gly-zdap 8195:phhs-oxadiaz-gly-betathioph 8196:bhs-25thiaz-gly-betafphe 8197:ibhs-24thioph-bala-betaipr 8198:gua-25thioph-gly-betapyr 8199:phhs-nme35pyr-gly-betameph 8200:ibhs-25oxaz-gly-zdap 8201:ibhs-25methiaz-gly-zdap 8202:bhs-24thiaz-ala-betainyl 8203:bhs-nme35pyr-bala-betathiome 8204:bhs-24thiaz-bala-betathiobe 8205:tolhs-24thiaz-bala-betapym 8206:tolhs-25methiaz-gly-betathioph 8207:tolhs-ithiadiaz-bala-betapym 8208:tolhs-25oxaz-bala-betaimid 8209:tolhs-ithiadiaz-bala-betaipro 8210:bhs-25thiaz-bala-beta13bendi 8211:2pmhs-24thioph-gly-betabpy 8212:ibhs-ithiadiaz-bala-betadcph 8213: bhs-24thiaz-gly-betabnaphth 8214: bhs-25oxaz-bala-betahmno 8215: 2py-me24oxaz-leu-betaph 8216: tolhs-25methiaz-gly-betahph 8217: phhs-25oxaz-gly-betapyr 8218: bhs-25oxaz-nmgly-betafphe 8219: bim-25thiaz-gly-betameph 8220: bhs-oxadiaz-bala-aspbzla 8221: bim-25oxaz-gly-betahb 108222: phhs-me25thiaz-ala-zdap 8223: tolhs-me24oxaz-bala-betapy 8224: gua-24thiaz-gly-betahbcph 8225: bim-24oxaz-ala-betainyl 8226: 2pmhs-25oxaz-gly-betathio3 158227: bhs-25oxaz-bala-betadcphtb 8228: 2py-me24oxaz-gly-betaph 8229: bhs-24thiaz-nmgly-beta34dcph 8230: ibhs-nme35pyr-bala-beta13bendi 8231: bhs-me24thiaz-gly-psdap 208232: ibhs-nme35pyr-bala-betadtrif 8233: tolhs-nme35pyr-bala-betaoxope 8234: 2py-25fur-leu-betapy 8235: tolhs-nme35pyr-bala-betahc 8236: 2py-me24thiaz-ala-psdap 258237: bim-me24thiaz-ala-betapy 8238: tolhs-25thiaz-gly-betabthioph 8239: 2py-25thioph-bala-psdap 8240: ibhs-25thiaz-gly-betahdcph 8241: bim-26py-gly-psdap 308242: 2py-35fur-gly-betapy 8243: phhs-25methiaz-bala-betabph 8244: phhs-25thiaz-bala-betahbcph 8245: ibhs-24thioph-gly-betadcphtb 8246: 2py-me25thiaz-leu-betaph 358247: ibhs-25thiaz-gly-betaipr 8248: ibhs-24thioph-gly-betacbph 8249: ibhs-25methiaz-bala-betaamibe DEMANDES OU BREVETS VOLUMINEUX
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Claims (28)

We claim:
1. A compound of the formula I
A-E-G-L I
where A, E, G and L have the following meanings:
L a structural element of the formula I L, where a is 0 or 1, T is a COOH group or a radical which can be hydrolyzed to COOH, R2 is hydrogen, NHSO2R21, NHCOR21 or NHCOOR22, where R21 is a branched or unbranched, optionally substituted C1-C6-alkyl, C3-C6-cycloalkyl, C1-C4-alkyl-C3-C6-cycloalkyl radical, C5-C12-bicycloalkyl or C6-C18-tricycloalkyl radical, an up to trisubstituted, with identical or different radicals, aryl, alkylaryl, hetarylalkyl radical or 3- to 6-membered, saturated, unsaturated or aromatic heterocycle which may contain up to three different or identical heteroatoms O, N, S, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and this ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, R22 is a branched or unbranched, optionally substituted C1-C6-alkyl radical or an optionally substituted aryl or alkylaryl radical, R3 is hydrogen or -(CH2)b-(X)c -R31, where b is 0, 1, 2 or 3, c is 0 or 1, X is -SO2-, -S-, -O-, -CO-, -NH-SO2-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-,-CO-N(R31)-, -N(R31)-CO-, -SO2-NH-, -SO2-N(R31)- or -N(R31)-SO2-R31 is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted C1-C6-alkyl, C1-C4-alkoxy, -O-alkylaryl or -O-aryl radical, an amino radical with primary or optionally secondary or tertiary substitution, an optionally C1-C4-alkyl- or aryl-substituted C2-C6-alkynyl or C2-C6-alkenyl radical, a C5-C12-bicycloalkyl, C6-C18-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3-C8-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, and~
R4 is hydrogen, or a branched or unbranched, optionally substituted C~-a-alkyl, C3-C6-alkenyl, C3-C6-alkynyl or C3-C6-cycloalkyl radical, G a structural element of the formula I G, where d is 0, 1 or 2, R5 is hydrogen, a hydroxyl group, a branched or unbranched, optionally substituted C1-C6-alkyl, C1-C4-alkoxy, -O-alkylaryl or -O-aryl radical, an amino radical with primary or optionally secondary or tertiary substitution, an optionally C1-C4-alkyl- or aryl-substituted C2-C6-alkynyl or C2-C6-alkenyl radical, a C5-C12-bicycloalkyl, C6-C18-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3-8-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, or the side chain of a natural amino acid, R6 is hydrogen or a branched or unbranched, optionally substituted C1-4-alkyl, C3-C6-alkenyl, C3-C6-alkynyl or C3-C6-cycloalkyl radical, E a structural element of the formula I E
-(NH)g-(CH2)f-Q-(CH2)e-CO- I E
where a is 0, 1 or 2, f is 0 or 1, g is 0 or 1, Q is a doubly linked, optionally substituted hetaryl radical, it being possible for two substituents together to be a saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and this ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, A one of the structural elements of the formulae I A1 to I A20, where R10, R11 are, independently of one another, hydrogen, -(CH2)h-(Y)i-R101, or the two radicals together are a 3- to 8-membered, optionally substituted, saturated, unsaturated or aromatic N-heterocycle which may additionally contain two other, identical or different heteroatoms O, N or S, where h is 0, 1, 2 or 3, i is 0 or 1, Y is -SO2-, -S-, -O-, -CO-, -NH-SO2-, -O-CO-, -CO-O-, -NH-CO-, -CO-NH-, -CO-N(R101)-, -N(R101)-CO-, -SO2-NH-, -N(R101)-SO2- or -SO2-N(R101)- and R101 is a hydroxyl group, a branched or unbranched, optionally substituted C1-C6-alkyl, C1-C4-alkoxy, -O-alkylaryl or -O-aryl radical, an amino radical with primary or optionally secondary or tertiary substitution, an optionally C1-C4-alkyl- or aryl-substituted C2-C6-alkynyl or C2-C6-alkenyl radical, a C5-C12-bicycloalkyl, C6-C18-tricycloalkyl radical or a 3- to 6-membered, saturated or unsaturated heterocycle which is substituted by up to three identical or different radicals and which may contain up to three different or identical heteroatoms O, N, S, C3-8-cycloalkyl, aryl or hetaryl radical, it being possible for two radicals together to be a fused, saturated, unsaturated or aromatic carbocycle or heterocycle which may contain up to three different or identical heteroatoms O, N, S, and the ring can optionally be substituted, or another, optionally substituted, saturated, unsaturated or aromatic ring can be fused to this ring, R12 is a branched or unbranched, optionally substituted C1-C4-alkyl, alkylaryl, C3-C6-cycloalkyl or C1-C4-alkyl-C3-C6-cycloalkyl radical or an optionally substituted aryl radical, R13 is hydrogen, -OH, -CN, -CONH2, a branched or unbranched, optionally substituted C1-C4-alkyl, C1-C4-alkoxy or -O-CO-C1-C4-alkyl radical, or an optionally substituted alkylaryl, -O-alkylaryl, -O-CO-aryl, -O-CO-alkylaryl or -O-CO-allyl radical, R14 is hydrogen, a branched or unbranched, optionally substituted C1-C4-alkyl, -CO-O-C1-C4-alkyl, alkylaryl, -CO-O-alkylaryl, -CO-O-allyl, -CO-C,-C4-alkyl, -CO-alkylaryl or -CO-allyl radical, R15 is hydrogen, a branched or unbranched, optionally substituted C1-C4-alkyl radical or an optionally substituted aryl or alkylaryl radical, R16, R17 are, independently of one another, -NH2, halogen or a branched or unbranched, optionally substituted C1-C4-alkyl or C1-C4-alkoxy radical or an optionally substituted aryl radical, Z1, Z2, Z3, Z4 are, independently of one another, CH, C-CH3, C-OCH3, C-CI or N, and the physiologically tolerated salts, prodrugs and the enantiomerically pure or diastereomerically pure and tautomeric forms.
2. A pharmaceutical preparation for oral or parenteral administration, comprising at least one compound as claimed in claim 1 besides conventional pharmaceutical excipients.
3. The use of a compound as claimed in claim 1 for producing drugs for treating diseases.
4. The use as claimed in claim 3 of a compound as claimed in claim 1 as integrin receptor antagonist.
5. The use as claimed in claim 4 of a compound as claimed in claim 1 as antagonist of the .alpha.v.beta.3 integrin receptor.
6. The use of a compound as claimed in claim 1 for producing drugs for treating diseases in which an integrin receptor is involved.
7. The use as claimed in claim 6 of a compound as claimed in claim 1 for treating diseases in which the .alpha.v.beta.3 integrin receptor is involved.
8. The use as claimed in claim 7 of a compound as claimed in claim 1 for treating atherosclerosis, rheumatoid arthritis, restenosis after vessel injury, angioplasty, acute kidney failure, angiogenesis-associated microangiopathies, diabetic angiopathies, blood platelet-mediated vascular occlusion, arterial thrombosis, congestive heart failure, myocardial infarct, stroke, cancer, osteoporosis, high blood pressure, psoriasis or viral, parasitic or bacterial diseases, inflammations, wound healing, hyperparathyroidism, Paget's disease, malignant hypercalcemia or metastatic osteolytic lesions.
9. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of inhibitors of blood platelet adhesion, activation or aggregation, anticoagulants which prevent thrombin activity or formation, antagonists of blood platelet-activating compounds or selectin antagonists.
10. The use of the pharmaceutical preparation as claimed in claim 9 for producing a drug for treating blood platelet-mediated vascular occlusion or thrombosis.
11. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of inhibitors of blood platelet activation or aggregation, serine protease inhibitors, fibrinogen-reducing compounds, selectin antagonists, antagonists of ICAM-1 or VCAM-1 inhibitors of leukocyte adhesion inhibitors of vessel wall transmigration, fibrinolysis-modulating compounds, inhibitors of complement factors, endothelin receptor antagonists, tyrosine kinase inhibitors, antioxidants or interleukin 8 antagonists.
12. The use of the pharmaceutical preparation as claimed in claim 11 for producing a drug for treating myocardial infarct or stroke.
13. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of endothelia antagonists, ACE inhibitors, angiotensin receptor antagonists, endopeptidase inhibitors, beta blockers, calcium channel blockers, phosphodiesterase inhibitors or caspase inhibitors.
14. The use of the pharmaceutical preparation as claimed in claim 13 for producing a drug for treating congestive heart failure.
15. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of thrombin inhibitors, inhibitors of factor Xa, inhibitors of the coagulation pathway which leads to thrombin formation, inhibitors of blood platelet adhesion, activation or aggregation, endothelia receptor antagonists, nitric oxide synthase inhibitors, CD44 antagonists, selectin antagonists, MCP-1 antagonists, inhibitors of signal transduction in proliferating cells, antagonists of the cellular response mediated by EGF, PDGF, VEGF or bFGF, or antioxidants.
16. The use of the pharmaceutical preparation as claimed in claim 15 for producing a drug for treating restenosis after vessel injury or stent implantation.
17. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of antagonists of the cellular response mediated by EGF, PDGF, VEGF or bFGF, heparin or low molecular weight heparins or other GAGs, inhibitors of MMPs, selectin antagonists, endothelia antagonists, ACE inhibitors, angiotensin receptor antagonists, glycosylation inhibitors or AGE formation inhibitors or antagonists of their receptors.
18. The use of the pharmaceutical preparation as claimed in claim 17 for producing a drug for treating diabetic angiopathies.
19. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of lipid-lowering compounds, selectin antagonists, antagonists of ICAM-1 or VCAM-1 heparin or low molecular weight heparin or other GAGs, inhibitors of MMPs, endothelia antagonists, apolipoprotein A1 antagonists, cholesterol antagonists, HMG-CoA reductase inhibitors, ACAT inhibitors, ACE inhibitors, angiotensin receptor antagonists, tyrosine kinase inhibitors, protein kinase C inhibitors, calcium channel blockers, LDL receptor function stimulants, antioxidants or free radical scavengers.
20. The use of the pharmaceutical preparation as claimed in claim 19 for producing a drug for treating atherosclerosis.
21. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of cytostatic or antineoplastic compounds, compounds which inhibit proliferation or heparin or low molecular weight heparins or other GAGs.
22. The use of the pharmaceutical preparation as claimed in claim 21 for producing a drug for treating cancer.
23. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of compounds for antiresorptive therapy, compounds for hormone replacement therapy, recombinant human growth hormone, bisphosphonates, compounds for calcitonin therapy, calcitonin stimulants, calcium channel blockers, bone formation stimulants, interleukin-6 antagonists or Src tyrosine kinase inhibitors.
24. The use of the pharmaceutical preparation as claimed in claim 23 for producing a drug for treating osteoporosis.
25. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, where appropriate pharmaceutical excipients and at least one other compound selected from the group of TNF antagonists, antagonists of VLA-4 or VCAM-1, antagonists of LFA-1, Mac-1 or ICAMs, complement inhibitors, immunosuppressants, interleukin-1, -5 or -8 antagonists or dihydrofolate reductase inhibitors.
26. The use of the pharmaceutical preparation as claimed in claim 25 for producing a drug for treating rheumatoid arthritis.
27. A pharmaceutical preparation comprising at least one compound as claimed in claim 1, with appropriate pharmaceutical excipients and at least one other compound selected from the group of collagenase, PDGF antagonists or MMPs.
28. The use of the pharmaceutical preparation as claimed in claim 27 for producing a drug for improving wound healing.
CA002371604A 1999-04-28 2000-04-17 Integrin receptor antagonists Abandoned CA2371604A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DE1999119218 DE19919218A1 (en) 1999-04-28 1999-04-28 New peptide compounds, e.g. aza-heterocyclic substituted beta-alanine derivatives, are integrin receptor antagonists useful e.g. for treating atherosclerosis, cancer, osteoporosis, hypertension or inflammation
DE19919218.9 1999-04-28
DE19948269.1 1999-10-06
DE1999148269 DE19948269A1 (en) 1999-10-06 1999-10-06 New compounds as integrin antagonists useful for treating e.g. cardiovascular disorders, rheumatoid arthritis, kidney failure, stroke, cancer, osteoporosis, psoriasis or infection
PCT/EP2000/003469 WO2000066618A1 (en) 1999-04-28 2000-04-17 Integrin receptor antagonists

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DE10204789A1 (en) * 2002-02-06 2003-08-14 Merck Patent Gmbh Inhibitors of the integrin alpha¶v¶beta6
KR100759130B1 (en) * 2005-02-12 2007-09-19 휴메드 주식회사 Stent Coated with Anti-integrin Antibody and Process for Preparing the Same
US8716320B2 (en) * 2006-07-21 2014-05-06 Replidyne, Inc. Antibacteriall heterocyclic ureas
US8293919B2 (en) 2007-07-23 2012-10-23 Crestone, Inc. Antibacterial sulfone and sulfoxide substituted heterocyclic urea compounds
US8148380B2 (en) 2007-07-23 2012-04-03 Crestone, Inc. Antibacterial amide and sulfonamide substituted heterocyclic urea compounds
MX2011012717A (en) * 2009-06-02 2011-12-14 Boehringer Ingelheim Int DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLI C ACID AMIDES.
BR112014016736A8 (en) * 2012-01-27 2017-07-04 Hoffmann La Roche compound, pharmaceutical composition, method for treatment, use of a compound and invention
RU2731807C1 (en) * 2020-05-05 2020-09-08 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт ревматологии имени В.А.Насоновой» (ФГБНУ НИИР им. В.А. Насоновой) Method for determining indications to beginning of reception of genetic engineering biological preparations with ineffectiveness of basic anti-inflammatory preparations in early forms of psoriatic arthritis

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