CA2268849A1 - End-sampling thief probe - Google Patents

End-sampling thief probe Download PDF

Info

Publication number: CA2268849A1
Authority: CA; Canada
Prior art keywords: hollow; hollow rod; conical tip; rod; thief
Prior art date: 1996-10-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

CA002268849A

Other languages

English (en)

French (fr)

Inventor

Priscilla A. Robinson

Erinn K. Gleason

Dean Brone

Fernando J. Muzzio

Carolyn Wightman

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Rutgers State University of New Jersey

Original Assignee

Individual

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-10-25

Filing date

1997-10-21

Publication date

1998-05-07

1997-05-12 Priority claimed from GBGB9709586.3A external-priority patent/GB9709586D0/en

1997-10-21 Application filed by Individual filed Critical Individual

1998-05-07 Publication of CA2268849A1 publication Critical patent/CA2268849A1/en

Status Abandoned legal-status Critical Current

Links

239000000523 sample Substances 0.000 title claims abstract description 101
238000005070 sampling Methods 0.000 title claims abstract description 49
238000000034 method Methods 0.000 claims abstract description 14
239000000463 material Substances 0.000 claims description 12
239000008247 solid mixture Substances 0.000 claims description 10
239000007787 solid Substances 0.000 claims description 8
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 6
229910052782 aluminium Inorganic materials 0.000 claims description 6
229910000906 Bronze Inorganic materials 0.000 claims description 3
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 3
229910000831 Steel Inorganic materials 0.000 claims description 3
239000010974 bronze Substances 0.000 claims description 3
229910052802 copper Inorganic materials 0.000 claims description 3
239000010949 copper Substances 0.000 claims description 3
KUNSUQLRTQLHQQ-UHFFFAOYSA-N copper tin Chemical compound [Cu].[Sn] KUNSUQLRTQLHQQ-UHFFFAOYSA-N 0.000 claims description 3
239000010959 steel Substances 0.000 claims description 3
239000000843 powder Substances 0.000 description 32
239000000203 mixture Substances 0.000 description 26
239000002245 particle Substances 0.000 description 25
239000011324 bead Substances 0.000 description 10
238000003780 insertion Methods 0.000 description 10
230000037431 insertion Effects 0.000 description 10
238000002156 mixing Methods 0.000 description 9
238000002474 experimental method Methods 0.000 description 7
238000013461 design Methods 0.000 description 3
239000008187 granular material Substances 0.000 description 3
238000004519 manufacturing process Methods 0.000 description 3
238000005259 measurement Methods 0.000 description 3
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 2
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 2
239000004411 aluminium Substances 0.000 description 2
239000003610 charcoal Substances 0.000 description 2
239000008101 lactose Substances 0.000 description 2
239000008188 pellet Substances 0.000 description 2
239000004576 sand Substances 0.000 description 2
238000005204 segregation Methods 0.000 description 2
244000144619 Abrus precatorius Species 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
238000004458 analytical method Methods 0.000 description 1
238000013459 approach Methods 0.000 description 1
229910000019 calcium carbonate Inorganic materials 0.000 description 1
239000002775 capsule Substances 0.000 description 1
238000012512 characterization method Methods 0.000 description 1
239000003086 colorant Substances 0.000 description 1
239000002131 composite material Substances 0.000 description 1
238000011109 contamination Methods 0.000 description 1
239000013068 control sample Substances 0.000 description 1
230000003247 decreasing effect Effects 0.000 description 1
239000002552 dosage form Substances 0.000 description 1
239000003814 drug Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
238000009472 formulation Methods 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
239000011521 glass Substances 0.000 description 1
230000008595 infiltration Effects 0.000 description 1
238000001764 infiltration Methods 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
230000035515 penetration Effects 0.000 description 1
230000003389 potentiating effect Effects 0.000 description 1
238000004445 quantitative analysis Methods 0.000 description 1
238000012360 testing method Methods 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G01N1/08—Devices for withdrawing samples in the solid state, e.g. by cutting involving an extracting tool, e.g. core bit
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/0091—Powders
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N2001/1006—Dispersed solids

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Physics & Mathematics (AREA)
General Physics & Mathematics (AREA)
Immunology (AREA)
Pathology (AREA)
Engineering & Computer Science (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Sampling And Sample Adjustment (AREA)

CA002268849A 1996-10-25 1997-10-21 End-sampling thief probe Abandoned CA2268849A1 (en)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US2963196P	1996-10-25	1996-10-25
US60/029,631		1996-10-25
GBGB9709586.3A GB9709586D0 (en)	1997-05-12	1997-05-12	End-sampling thief probe
GB9709586.3		1997-05-12
PCT/US1997/019062 WO1998018558A1 (en)	1996-10-25	1997-10-21	End-sampling thief probe

Publications (1)

Publication Number	Publication Date
CA2268849A1 true CA2268849A1 (en)	1998-05-07

Family

ID=26311519

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CA002268849A Abandoned CA2268849A1 (en)	1996-10-25	1997-10-21	End-sampling thief probe

Country Status (4)

Country	Link
EP (1)	EP0934117A1 (ja)
JP (1)	JP2001503147A (ja)
CA (1)	CA2268849A1 (ja)
WO (1)	WO1998018558A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH10263421A (ja) *	1997-03-21	1998-10-06	Fukae Kasei Kk	粉体分与用ディスポーザブルピペットチップと装置
JP5321408B2 (ja) *	2008-10-24	2013-10-23	大正製薬株式会社	棒状サンプラー
JP2012026758A (ja) *	2010-07-20	2012-02-09	Chubu Electric Power Co Inc	非常用ガス処理装置保守方法
WO2019195895A1 (en)	2018-04-12	2019-10-17	Pharma and Nutraceutical PD Pty Ltd	Sampling device

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4528161A (en) *	1981-08-31	1985-07-09	American Hospital Supply Corp.	Probe for automated liquid dispenser
US4750373A (en) *	1987-01-22	1988-06-14	Shapiro Justin J	Adjustable volume, pressure-generating pipette sampler
US5045286A (en) *	1988-02-25	1991-09-03	Olympus Optical Co., Ltd.	Device for aspirating a fixed quantity of liquid
EP0443227A1 (en) *	1990-02-19	1991-08-28	Ito Corporation	Analytical microsyringe
JP3152727B2 (ja) *	1992-03-31	2001-04-03	株式会社東芝	ノズル型分析装置
US5512248A (en) *	1993-11-23	1996-04-30	Van; Jack F. J.	Twin-probe blood sample diluting device

1997
- 1997-10-21 WO PCT/US1997/019062 patent/WO1998018558A1/en not_active Application Discontinuation
- 1997-10-21 JP JP10520569A patent/JP2001503147A/ja active Pending
- 1997-10-21 EP EP97913724A patent/EP0934117A1/en not_active Withdrawn
- 1997-10-21 CA CA002268849A patent/CA2268849A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2001503147A (ja)	2001-03-06
EP0934117A1 (en)	1999-08-11
WO1998018558A1 (en)	1998-05-07

Legal Events

Date	Code	Title	Description
2002-05-15	EEER	Examination request
2004-10-21	FZDE	Discontinued

Publication	Publication Date	Title
US5996426A (en)	1999-12-07	End-sampling thief probe
US6339966B1 (en)	2002-01-22	Bulk powder sampler with removable partitions and method of using
US6910393B2 (en)	2005-06-28	Powder sampling method and apparatus
Berman et al.	1995	Blend uniformity and unit dose sampling
WO2004079338A2 (en)	2004-09-16	Methods and systems for dissolution testing
US5476017A (en)	1995-12-19	Unit dose bulk material sampling apparatus
Germani et al.	1991	Automated scanning electron microscopy for atmospheric particle analysis
CA2268849A1 (en)	1998-05-07	End-sampling thief probe
Brettell et al.	2018	Analysis of drugs of abuse by gas chromatography–mass spectrometry (GC-MS)
US6631650B1 (en)	2003-10-14	Thief sampling probe
Dreassi et al.	1995	Near-infrared reflectance spectrometry in the determination of the physical state of primary materials in pharmaceutical production
DE4101429C2 (de)	1994-07-28	Verbrennungsvorrichtung
US5703301A (en)	1997-12-30	Unit dose bulk material sampling apparatus with controlled pressure applicator
CN110376291A (zh)	2019-10-25	一种黄连对照提取物及其制备方法和应用
Lovelady et al.	1975	Quantitative determination of epinephrine and norepinephrine in the picogram range by flame ionization gas-liquid chromatography
Chang et al.	1996	An evaluation of a unit-dose compacting sample thief and a discussion of content uniformity testing and blending validation issues
De Forest	1974	The Potential of Pyrolysis-Gas Chromatography for the Pattern Individualization of Macromolecular Materials
US3879181A (en)	1975-04-22	Gas chromatograph, specimen capsule for use therein and process for gas chromatography
Prager et al.	1979	Gas-liquid chromatographic determination of morphine, heroin, and ***e
JP2004309253A (ja)	2004-11-04	サンプラー
DE19720687C1 (de)	1998-07-30	Pyrolyseröhrchen für die Gaschromatographie, Pyrolysatorvorrichtung, gaschromatographisches Verfahren sowie Gaschromatograph
US20210302281A1 (en)	2021-09-30	Powder Sampling Thief
Maynard	2015	Five fundamentals for effective blend sampling
DE69900902T2 (de)	2002-09-26	Kryostat-düse und methode zur anwendung eines kryostaten
Li et al.	2023	Advances in the application of chromatographic techniques in forensic toxicology fund