CA2223596A1 - Biocompatible hydroxyapatite formulations and uses therefor - Google Patents
Biocompatible hydroxyapatite formulations and uses therefor Download PDFInfo
- Publication number
- CA2223596A1 CA2223596A1 CA002223596A CA2223596A CA2223596A1 CA 2223596 A1 CA2223596 A1 CA 2223596A1 CA 002223596 A CA002223596 A CA 002223596A CA 2223596 A CA2223596 A CA 2223596A CA 2223596 A1 CA2223596 A1 CA 2223596A1
- Authority
- CA
- Canada
- Prior art keywords
- liquid phase
- biocompatible
- calcium phosphate
- phosphate salts
- formulation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 229910052588 hydroxylapatite Inorganic materials 0.000 title claims abstract description 107
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- 239000007791 liquid phase Substances 0.000 claims abstract description 161
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims abstract description 110
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- YIGWVOWKHUSYER-UHFFFAOYSA-F tetracalcium;hydrogen phosphate;diphosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[Ca+2].OP([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O YIGWVOWKHUSYER-UHFFFAOYSA-F 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/02—Surgical adhesives or cements; Adhesives for colostomy devices containing inorganic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/12—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/32—Phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00179—Ceramics or ceramic-like structures
- A61F2310/00293—Ceramics or ceramic-like structures containing a phosphorus-containing compound, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00389—The prosthesis being coated or covered with a particular material
- A61F2310/00592—Coating or prosthesis-covering structure made of ceramics or of ceramic-like compounds
- A61F2310/00796—Coating or prosthesis-covering structure made of a phosphorus-containing compound, e.g. hydroxy(l)apatite
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Transplantation (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47121695A | 1995-06-06 | 1995-06-06 | |
| US46990995A | 1995-06-06 | 1995-06-06 | |
| US46808495A | 1995-06-06 | 1995-06-06 | |
| US08/471,216 | 1995-06-06 | ||
| US08/469,909 | 1995-06-06 | ||
| US08/468,084 | 1995-06-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2223596A1 true CA2223596A1 (en) | 1996-12-12 |
Family
ID=27413043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002223596A Abandoned CA2223596A1 (en) | 1995-06-06 | 1996-06-03 | Biocompatible hydroxyapatite formulations and uses therefor |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0830149A1 (ja) |
| JP (1) | JPH11506659A (ja) |
| AU (1) | AU723740B2 (ja) |
| BR (1) | BR9608344A (ja) |
| CA (1) | CA2223596A1 (ja) |
| WO (1) | WO1996039202A1 (ja) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5891558A (en) * | 1994-11-22 | 1999-04-06 | Tissue Engineering, Inc. | Biopolymer foams for use in tissue repair and reconstruction |
| US6143948A (en) * | 1996-05-10 | 2000-11-07 | Isotis B.V. | Device for incorporation and release of biologically active agents |
| CA2205104A1 (en) * | 1996-05-10 | 1997-11-10 | Eugenia Ribeiro De Sousa Fidalgo Leitao | Device for incorporation and release of biologically active agents |
| CA2287228A1 (en) * | 1997-04-24 | 1998-10-29 | Tetsuo Hoshino | Apatite-coated solid composition |
| WO1999020319A1 (de) * | 1997-10-21 | 1999-04-29 | Augmentec Aktiengesellschaft Implantologie-Epithetik | Implantat aus resorbierbarem, keramischem material |
| NL1008582C2 (nl) * | 1998-01-05 | 1999-07-06 | Vrije Universiteit | Botmateriaal. |
| AR019025A1 (es) * | 1998-04-09 | 2001-12-26 | Roche Diagnostics Gmbh | Uso de eritropoyetina en bajas dosis para producir un preparado farmaceutico para el tratamiento de hemocromatosis, preparado farmaceutico combinadoutilizado segun dicho uso y envase farmaceutico unitario que contiene al referido preparado farmaceutico combinado |
| ATE226836T1 (de) * | 1998-07-02 | 2002-11-15 | Stichting Skeletal Tissue Engi | Knochenzement mit antimikrobiellen peptiden |
| US6123925A (en) * | 1998-07-27 | 2000-09-26 | Healthshield Technologies L.L.C. | Antibiotic toothpaste |
| JP4778143B2 (ja) * | 1998-07-28 | 2011-09-21 | アルツケム トロストベルク ゲゼルシャフト ミット ベシュレンクテル ハフツング | 骨または軟骨細胞および組織の治療用クレアチン化合物の使用 |
| EP1226232A2 (en) * | 1999-10-15 | 2002-07-31 | Mount Sinai Hospital | Synthetic substrate for tissue formation |
| DK1229940T3 (da) | 1999-11-15 | 2014-08-18 | Piramal Healthcare Canada Ltd | Temperaturstyret og ph-afhængig selvgelerende, vandig biopolymeropløsning |
| AU1848601A (en) * | 1999-12-09 | 2001-06-18 | Bio Syntech Canada Inc | Mineral-polymer hybrid composition |
| SE520688C2 (sv) * | 2000-04-11 | 2003-08-12 | Bone Support Ab | Ett injicerbart ersättningsmaterial för benmineral |
| SE517168C2 (sv) | 2000-07-17 | 2002-04-23 | Bone Support Ab | En komposition för ett injicerbart ersättningsmaterial för benmineral |
| EP1228772A1 (en) * | 2001-02-01 | 2002-08-07 | AM-Pharma B.V. | Novel bone cement containing bioactive agents |
| AU2003279570A1 (en) * | 2002-11-12 | 2004-06-03 | The Circle For The Promotion Of Science And Engineering | Delivery agent, method of delivering a target substance to cells, method for producing delivery agent, composition for producing delivery agent, and kit for producing delivery agent |
| JP4654427B2 (ja) * | 2002-11-22 | 2011-03-23 | 独立行政法人産業技術総合研究所 | 骨形成を促進する水溶性タンパク質−リン酸カルシウム複合体およびその製造方法 |
| CN1732023A (zh) * | 2002-12-27 | 2006-02-08 | 血管技术国际股份公司 | 组合物和使用collajolie的方法 |
| FR2849436B1 (fr) * | 2002-12-27 | 2007-01-05 | Patrick Frayssinet | Particules et ceramiques de phosphates de calcium pour transfection in vivo et in vitro |
| US7067169B2 (en) | 2003-06-04 | 2006-06-27 | Chemat Technology Inc. | Coated implants and methods of coating |
| WO2005025605A1 (ja) * | 2003-09-09 | 2005-03-24 | Two Cells Co. Ltd. | 歯周病と歯髄疾患の治療剤と治療方法 |
| JP4604238B2 (ja) * | 2003-09-19 | 2011-01-05 | 独立行政法人産業技術総合研究所 | 燐酸カルシウムと生理活性物質を含有する高分子複合体、その製造方法及びそれを用いた医療用材料 |
| JP4569946B2 (ja) * | 2003-10-21 | 2010-10-27 | セルメディシン株式会社 | リン酸カルシウム微粒子 |
| SE0302983D0 (sv) | 2003-11-11 | 2003-11-11 | Bone Support Ab | Anordning för att förse spongiöst ben med benersättnings- och/eller benförstärkningsmaterial och förfarande i samband därmed |
| JP4199653B2 (ja) * | 2003-12-09 | 2008-12-17 | 松崎 浩巳 | 骨補填材 |
| US20050136764A1 (en) | 2003-12-18 | 2005-06-23 | Sherman Michael C. | Designed composite degradation for spinal implants |
| SE527528C2 (sv) | 2004-06-22 | 2006-04-04 | Bone Support Ab | Anordning för framställning av härdbar massa samt användning av anordningen |
| FR2885525B1 (fr) * | 2005-05-13 | 2009-09-18 | Urodelia Sa | Medicament notamment anti-cancereux, destine a des traitements par immunotherapie, en particulier autologue |
| US7799268B2 (en) | 2005-07-19 | 2010-09-21 | University Of Limerick | Implants |
| CA2629600C (en) | 2005-11-14 | 2011-11-01 | Biomet 3I, Inc. | Deposition of discrete nanoparticles on an implant surface |
| US9764057B2 (en) | 2007-06-06 | 2017-09-19 | Innotere Gmbh | Hydraulic cement-based implant material and use thereof |
| EP2077126A1 (en) * | 2008-01-07 | 2009-07-08 | Graftys | Analgesic apatitic calcium-phosphate cement |
| JP5806466B2 (ja) | 2008-01-28 | 2015-11-10 | バイオメット・３アイ・エルエルシー | 親水性を向上させたインプラント表面 |
| KR100973470B1 (ko) * | 2008-06-16 | 2010-08-02 | 인제대학교 산학협력단 | 칼시토닌-폴리포스페이트의 복합체 및 그의 제조방법 |
| US9180137B2 (en) | 2010-02-09 | 2015-11-10 | Bone Support Ab | Preparation of bone cement compositions |
| US8641418B2 (en) | 2010-03-29 | 2014-02-04 | Biomet 3I, Llc | Titanium nano-scale etching on an implant surface |
| EP2529764A1 (de) | 2011-05-31 | 2012-12-05 | Curasan AG | Biologisch degradierbares kompositmaterial |
| ES2671740T3 (es) | 2012-03-20 | 2018-06-08 | Biomet 3I, Llc | Superficie de tratamiento para una superficie de implante |
| US20140081422A1 (en) | 2012-09-10 | 2014-03-20 | Ortho Transmission, Llc | Transcutaneous Implant for Skeletal Attachment of External Prosthetic Devices |
| PL2958603T3 (pl) | 2013-02-20 | 2018-10-31 | Bone Support Ab | Ulepszone zestalanie utwardzalnego materiału zastępczego kości |
| CN112891639B (zh) * | 2021-01-21 | 2022-07-26 | 西北工业大学 | 一种超薄碳质皮肤修复材料及制备方法 |
| CN113913805B (zh) * | 2021-10-20 | 2023-08-22 | 中南大学湘雅医院 | 一种冷喷涂改性层及其应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USRE33221E (en) * | 1982-04-29 | 1990-05-22 | American Dental Association Health Foundation | Dental restorative cement pastes |
| EP0323632B1 (en) * | 1987-12-28 | 1992-07-15 | Asahi Kogaku Kogyo Kabushiki Kaisha | Composition for forming calcium phosphate type setting material and process for producing setting material |
| DE68915265T2 (de) * | 1988-08-10 | 1995-01-05 | Nitta Gelatin Kk | Ärztliches und zahnärztliches vernetzbares material. |
| JP2621622B2 (ja) * | 1990-09-27 | 1997-06-18 | 三菱マテリアル株式会社 | 水硬性リン酸カルシウムセメント |
| US5149368A (en) * | 1991-01-10 | 1992-09-22 | Liu Sung Tsuen | Resorbable bioactive calcium phosphate cement |
| US5522893A (en) * | 1993-03-12 | 1996-06-04 | American Dental Association Health Foundation | Calcium phosphate hydroxyapatite precursor and methods for making and using the same |
| JPH0731673A (ja) * | 1993-07-19 | 1995-02-03 | Asahi Optical Co Ltd | 生体吸収性高分子含有硬化型骨補填材 |
-
1996
- 1996-06-03 BR BR9608344A patent/BR9608344A/pt not_active Application Discontinuation
- 1996-06-03 WO PCT/US1996/008652 patent/WO1996039202A1/en not_active Application Discontinuation
- 1996-06-03 JP JP9501179A patent/JPH11506659A/ja active Pending
- 1996-06-03 CA CA002223596A patent/CA2223596A1/en not_active Abandoned
- 1996-06-03 EP EP96919055A patent/EP0830149A1/en not_active Withdrawn
- 1996-06-03 AU AU61496/96A patent/AU723740B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU723740B2 (en) | 2000-09-07 |
| MX9709904A (es) | 1998-08-30 |
| JPH11506659A (ja) | 1999-06-15 |
| BR9608344A (pt) | 1999-01-05 |
| AU6149696A (en) | 1996-12-24 |
| EP0830149A1 (en) | 1998-03-25 |
| WO1996039202A1 (en) | 1996-12-12 |
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Legal Events
| Date | Code | Title | Description |
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| FZDE | Dead |