CA2170285A1 - Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid esters as medicaments - Google Patents

Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid esters as medicaments

Info

Publication number
CA2170285A1
CA2170285A1 CA002170285A CA2170285A CA2170285A1 CA 2170285 A1 CA2170285 A1 CA 2170285A1 CA 002170285 A CA002170285 A CA 002170285A CA 2170285 A CA2170285 A CA 2170285A CA 2170285 A1 CA2170285 A1 CA 2170285A1
Authority
CA
Canada
Prior art keywords
general formula
carbon atoms
compounds
methyl
atherosclerotic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002170285A
Other languages
English (en)
French (fr)
Inventor
Siegfried Zaiss
Dieter Neuser
Johannes-Peter Stasch
Siegfried Goldmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2170285A1 publication Critical patent/CA2170285A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002170285A 1993-08-27 1994-08-16 Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid esters as medicaments Abandoned CA2170285A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4328884A DE4328884A1 (de) 1993-08-27 1993-08-27 Verwendung von N-alkylierten 1,4-Dihydropyridincarbonsäureestern als Arzneimittel
DEP4328884.7 1993-08-27

Publications (1)

Publication Number Publication Date
CA2170285A1 true CA2170285A1 (en) 1995-03-02

Family

ID=6496196

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002170285A Abandoned CA2170285A1 (en) 1993-08-27 1994-08-16 Use of n-alkylated 1,4-dihydropyridine dicarboxylic acid esters as medicaments

Country Status (13)

Country Link
EP (1) EP0714301A1 (de)
JP (1) JPH09501923A (de)
KR (1) KR960703594A (de)
CN (1) CN1129906A (de)
AU (1) AU7613594A (de)
BG (1) BG100367A (de)
CA (1) CA2170285A1 (de)
CZ (1) CZ43896A3 (de)
DE (1) DE4328884A1 (de)
HU (1) HUT75302A (de)
NO (1) NO960777L (de)
PL (1) PL313116A1 (de)
WO (1) WO1995005823A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19741694C2 (de) * 1997-09-18 2002-10-31 Schering Ag Verwendung von Komplexen, deren Ligand ein Bis-Amin-Oxim-Derivat oder ein N¶2¶S¶2¶-Derivat und deren Zentralatom ein Radionuklid ist
EP1458682B1 (de) * 2001-12-20 2006-08-30 Bayer HealthCare AG 1, 4-dihydro-1, 4-diphenylpyridin-derivate
CA2854252C (en) * 2011-11-24 2016-11-29 Lipidart Kutato Fejleszto Es Tanacsado Kft. 1,4-dihydropyridine derivatives with hsp modulating activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3222367A1 (de) * 1982-06-15 1983-12-15 Bayer Ag, 5090 Leverkusen Verwendung von 1,4-dihydropyridinen in antiarteriosklerotika und deren herstellung
EP0169009A3 (de) * 1984-07-17 1988-08-31 FISONS plc Dihydropyridinderivate und ihre Herstellung, Formulierung und Verwendung als Pharmazeutika
DE4011695A1 (de) * 1990-04-11 1991-10-17 Bayer Ag Verwendung von n-alkylierten 1,4-dihydropyridindicarbonsaeureestern als arzneimittel, neue verbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DE4328884A1 (de) 1995-03-02
CN1129906A (zh) 1996-08-28
AU7613594A (en) 1995-03-21
PL313116A1 (en) 1996-06-10
HUT75302A (en) 1997-05-28
JPH09501923A (ja) 1997-02-25
EP0714301A1 (de) 1996-06-05
WO1995005823A1 (de) 1995-03-02
HU9600472D0 (en) 1996-04-29
CZ43896A3 (en) 1996-05-15
BG100367A (en) 1996-07-31
NO960777D0 (no) 1996-02-26
KR960703594A (ko) 1996-08-31
NO960777L (no) 1996-04-10

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Legal Events

Date Code Title Description
FZDE Discontinued