CA2066779A1 - Compositions a base de radionucleides therapeutiques stables, et leurs methodes de preparation - Google Patents

Compositions a base de radionucleides therapeutiques stables, et leurs methodes de preparation

Info

Publication number
CA2066779A1
CA2066779A1 CA 2066779 CA2066779A CA2066779A1 CA 2066779 A1 CA2066779 A1 CA 2066779A1 CA 2066779 CA2066779 CA 2066779 CA 2066779 A CA2066779 A CA 2066779A CA 2066779 A1 CA2066779 A1 CA 2066779A1
Authority
CA
Canada
Prior art keywords
therapeutic radionuclide
radionuclide
therapeutic
stabilizing agent
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA 2066779
Other languages
English (en)
Inventor
Jean-Luc Vanderheyden
Alan R. Fritzberg
Joseph E. Bugaj
Fu-Min Su
Prasanna Venkatesan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Poniard Pharmaceuticals Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2066779A1 publication Critical patent/CA2066779A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1093—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody conjugates with carriers being antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
CA 2066779 1989-09-22 1990-09-18 Compositions a base de radionucleides therapeutiques stables, et leurs methodes de preparation Abandoned CA2066779A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41137289A 1989-09-22 1989-09-22
US411,372 1989-09-22

Publications (1)

Publication Number Publication Date
CA2066779A1 true CA2066779A1 (fr) 1991-03-23

Family

ID=23628672

Family Applications (1)

Application Number Title Priority Date Filing Date
CA 2066779 Abandoned CA2066779A1 (fr) 1989-09-22 1990-09-18 Compositions a base de radionucleides therapeutiques stables, et leurs methodes de preparation

Country Status (4)

Country Link
EP (1) EP0493526A4 (fr)
JP (1) JPH05502219A (fr)
CA (1) CA2066779A1 (fr)
WO (1) WO1991004057A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993002652A2 (fr) * 1991-08-01 1993-02-18 Hybritech Incorporated Haptenes modifies efficaces en tant qu'agents therapeutiques et agents d'imagerie
ATE195322T1 (de) * 1994-03-16 2000-08-15 Mallinckrodt Inc Verwendung von oberflächenaktiven substanzen zur stabilisierung von peptiden und proteinen zur radiopharmazeutischen verwendung
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
EP2080526A4 (fr) * 2006-11-09 2012-11-07 Nihon Mediphysics Co Ltd Agent d'imagerie de diagnostic radioactif
WO2015017815A1 (fr) * 2013-08-01 2015-02-05 Rochester Institute Of Technology Agents modulaires d'imagerie contenant des acides aminés et des peptides

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1417003A (en) * 1972-06-22 1975-12-10 Radiochemical Centre Ltd Stabilisation of fibrinogen
US4364920A (en) * 1975-04-30 1982-12-21 Medi-Physics, Inc. Stable diagnostic reagents
US4232000A (en) * 1978-06-28 1980-11-04 The Procter & Gamble Company Radioactive scanning agents with stabilizer
CA1225930A (fr) * 1982-06-07 1987-08-25 Otto A. Gansow Anticorps monoclonaux conjugues avec des chelates metalliques
US4837003A (en) * 1984-09-13 1989-06-06 Mallinckrodt, Inc. Radiolabeled antibody fragments
US4897255A (en) * 1985-01-14 1990-01-30 Neorx Corporation Metal radionuclide labeled proteins for diagnosis and therapy
GB8510726D0 (en) * 1985-04-26 1985-06-26 Amersham Int Plc Stabilised radio-labelled compounds
US4935222A (en) * 1986-06-13 1990-06-19 University Of Cincinnati Procedure for isolating and purifying radioactive ligated rhenium pharmaceuticals and use thereof and kit
US4849509A (en) * 1987-02-20 1989-07-18 The Wistar Institute Monoclonal antibodies against melanoma-associated antigens and hybrid cell lines producing these antibodies
ATE106898T1 (de) * 1987-03-26 1994-06-15 Neorx Corp Metall-radionuklid-markierte proteine und glykoproteine zur diagnose und therapie.
AU2068588A (en) * 1987-08-12 1989-02-16 Immunomedics Inc. Preparation of radiolabeled conjugates
AU619218B2 (en) * 1987-11-06 1992-01-23 Abbott Laboratories Methods and materials for the preparation of metal labelled antibody solutions
US4880615A (en) * 1988-11-25 1989-11-14 Merck & Co., Inc. Stabilized radiopharmaceutical compositions

Also Published As

Publication number Publication date
EP0493526A4 (en) 1992-08-26
EP0493526A1 (fr) 1992-07-08
JPH05502219A (ja) 1993-04-22
WO1991004057A1 (fr) 1991-04-04

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Dead