CA1156648A - Process for preparing ergoline derivatives - Google Patents

Process for preparing ergoline derivatives

Info

Publication number
CA1156648A
CA1156648A CA000374134A CA374134A CA1156648A CA 1156648 A CA1156648 A CA 1156648A CA 000374134 A CA000374134 A CA 000374134A CA 374134 A CA374134 A CA 374134A CA 1156648 A CA1156648 A CA 1156648A
Authority
CA
Canada
Prior art keywords
beta
carbonyl
urea
ergoline
carboxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000374134A
Other languages
English (en)
French (fr)
Inventor
Patricia Salvati
Enrico Di Salle
Germano Bosisio
Anna M. Caravaggi
Aldemio Temperilli
Osvaldo Sapini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Application granted granted Critical
Publication of CA1156648A publication Critical patent/CA1156648A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000374134A 1980-04-03 1981-03-30 Process for preparing ergoline derivatives Expired CA1156648A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8011234 1980-04-03
GB8011234 1980-04-03
GB8040575 1980-12-18
GB8040575 1980-12-18

Publications (1)

Publication Number Publication Date
CA1156648A true CA1156648A (en) 1983-11-08

Family

ID=26275073

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000374134A Expired CA1156648A (en) 1980-04-03 1981-03-30 Process for preparing ergoline derivatives

Country Status (20)

Country Link
AT (1) AT375076B (es)
AU (1) AU540621B2 (es)
CA (1) CA1156648A (es)
CH (1) CH645896A5 (es)
CS (1) CS415291A3 (es)
DE (1) DE3112861A1 (es)
DK (1) DK148686C (es)
ES (1) ES8202003A1 (es)
FI (1) FI70412C (es)
FR (1) FR2479829B1 (es)
GR (1) GR74806B (es)
HK (1) HK67287A (es)
IE (1) IE51130B1 (es)
IL (1) IL62519A (es)
IT (2) IT1210473B (es)
NL (3) NL189462C (es)
NZ (1) NZ196670A (es)
PT (1) PT72785B (es)
SE (1) SE442637B (es)
YU (1) YU43011B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939665B2 (en) 2007-05-04 2011-05-10 Apotex Pharmachem Inc. Efficient process for the preparation of cabergoline and its intermediates

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2173189B (en) * 1985-02-21 1988-04-27 Maruko Pharmaceutical Co Ergoline derivatives and salts thereof and pharmaceutical compositions thereof
GB0409785D0 (en) 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
GB0505965D0 (en) 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
EP2067780A1 (en) * 2007-12-07 2009-06-10 Axxonis Pharma AG Ergoline derivatives as selective radical scavengers for neurons

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE396753B (sv) * 1970-05-18 1977-10-03 Richter Gedeon Vegyeszet Analogiforfarande for framstellning av en forening tillhorande dihydrolysergsyraserien

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7939665B2 (en) 2007-05-04 2011-05-10 Apotex Pharmachem Inc. Efficient process for the preparation of cabergoline and its intermediates

Also Published As

Publication number Publication date
SE442637B (sv) 1986-01-20
PT72785B (en) 1982-07-26
FI811025L (fi) 1981-10-04
IE51130B1 (en) 1986-10-15
SE8102131L (sv) 1981-10-04
DE3112861C2 (es) 1989-06-01
IT1205241B (it) 1989-03-15
YU43011B (en) 1989-02-28
GR74806B (es) 1984-07-12
DK148686B (da) 1985-09-02
FR2479829A1 (fr) 1981-10-09
ES500911A0 (es) 1982-01-16
DK148686C (da) 1986-03-10
NL189462B (nl) 1992-11-16
NL930091I2 (nl) 1995-01-02
NL189462C (nl) 1993-04-16
IL62519A0 (en) 1981-05-20
ES8202003A1 (es) 1982-01-16
DK150781A (da) 1981-10-04
FI70412B (fi) 1986-03-27
AT375076B (de) 1984-06-25
IT8120865A0 (it) 1981-04-01
PT72785A (en) 1981-05-01
IL62519A (en) 1984-01-31
AU540621B2 (en) 1984-11-29
NL8101509A (nl) 1981-11-02
HK67287A (en) 1987-09-25
IT8120866A0 (it) 1981-04-01
NZ196670A (en) 1982-12-07
ATA148481A (de) 1983-11-15
FI70412C (fi) 1986-09-19
FR2479829B1 (fr) 1987-07-24
IE810754L (en) 1981-10-03
DE3112861A1 (de) 1982-01-07
CS415291A3 (en) 1992-06-17
YU85181A (en) 1984-02-29
NL930091I1 (nl) 1993-10-01
IT1210473B (it) 1989-09-14
NL930092I1 (nl) 1993-10-01
CH645896A5 (de) 1984-10-31
AU6893781A (en) 1981-10-08

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Legal Events

Date Code Title Description
MKEX Expiry